The University of Illinois at Springfield (UIS) is a public university in Springfield, Illinois, United States. The university was established in 1969 as Sangamon State University by the Illinois General Assembly and became a part of the University of Illinois system on July 1, 1995. As a public liberal arts college, and the newest campus in the University of Illinois system, UIS is a member of the Council of Public Liberal Arts Colleges. UIS is also part of the American Association of State Colleges and Universities (AASCU) and the American Council on Education. The campus' main repository, Brookens Library, holds a collection of nearly 800,000 books and serials- in addition to accessible resources at the University of Illinois at Chicago and University of Illinois at Urbana-Champaign campuses.

The University of Illinois at Springfield serves roughly 5,700 students in 23 undergraduate programs, 20 master's programs, and a doctorate in Public Administration. The university was once one of the two upper-division and graduate universities in Illinois, but now accepts freshmen, transfer and graduate students.