Jonathan Dinman to Direct the Institute for Bioscience and Biotechnology Research
Jonathan Dinman, a professor in the Department of Cell Biology and Molecular Genetics at the University of Maryland, College Park (UMCP), has been named director of the Institute for Bioscience and Biotechnology Research (IBBR), effective November 1, 2024. Located in the heart of Maryland’s biotechnology corridor in Montgomery County, IBBR...
AD-X2 Controversy Screening at IBBR - November 20th
On Wednesday, November 20th at 3:00pm, IBBR will host a screening of the documentary "The AD-X2 Controversy." Set in the 1950s, during a time of booming economy and rapid scientific advancement, this 23-minute film tells the captivating story of a charismatic salesman who sought to profit from a chemical additive...
Saif Hasan Named UMB School of Medicine Graduate Program in Life Sciences (GPILS) Teacher of the Year
The University of Maryland School of Medicine proudly announced Dr. Saif Hasan as the recipient of this year’s Graduate Program in Life Sciences (GPILS) Teacher of the Year Award. This annual award honors a GPILS faculty member with an outstanding record of teaching graduate students. Receiving this award speaks to...
About IBBR
IBBR is a joint research enterprise of the University of Maryland, College Park, the University of Maryland, Baltimore, and the National Institute of Standards and Technology.
IBBR leverages state-of-art integrative methods for bioanalytical, biophysical and structural characterization of biomolecules: cryo-electron microscopy, nuclear magnetic resonance, x-ray crystallography, small angle neutron and x-ray scattering and mass spectrometry.
IBBR researchers seek to advance therapeutic development, biomanufacturing, and state-of-the-art measurement technologies, to support accelerated delivery of safe and effective medicines to the public.
IBBR is a major initiative and supported in part by the University of Maryland Strategic Partnership: MPowering the State (MPower) , an initiative designed to achieve innovation and impact through collaboration.
Connecting
IBBR Commons
Sophisticated state-of-the-art instrumentation and facilities, and in-house expertise located in shared space and dedicated to advance research, support collaboration and foster innovation of methods. Instrumentation and facilities include tools for high-resolution structural biology, bioanalytical and biophysical measurement, protein engineering and cell culture, advanced computation including artificial intelligence and deep learning methods, and general laboratory services. These capabilities and advanced training are available to IBBR scientists and collaborators.
IBBR Postdoc Program
The IBBR Postdoc Program (IPP) focuses on collaborative research involving basic science and technology development that advances therapeutic development, vaccine development, and biomanufacturing. IPP Fellow project teams are designed with a combination of the IPP Fellow career goals and priorities of project mentors who can be from academic, government, and/or industrial laboratories throughout the University of Maryland, NIST and the I-270 corridor.
NMRPipe
IBBR is home to NMRPipe, a popular collection of programs and scripts for manipulating multidimensional Nuclear Magnetic Resonance (NMR) data. The use of NMRPipe is noted in roughly 40% of all NMR structures accepted into the Protein Data Bank.
Upcoming Events
NIST Group Meeting; Jake Rostkowski
Wednesday, November 6, 2024 - 11:00am
BMD Staff Seminar R. Brinson/ Y. Zheng, .03/.04
R. Brinson/ Y. Zheng, .03/.04
Tuesday, November 19, 2024 - 11:00am
NIST Group Meeting; Kinjal Mondal
Wednesday, November 20, 2024 - 11:00am
Recent Publications
Biomimetic Redox Capacitor To Control the Flow of Electrons.
In biological systems, electrons, energy, and information "flow" through the redox modality, and we ask, does biology have redox capacitor capabilities for storing electrons? We describe emerging...
modXNA: A Modular Approach to Parametrization of Modified Nucleic Acids for Use with Amber Force Fields.
Modified nucleic acids have surged as a popular therapeutic route, emphasizing the importance of nucleic acid research in drug discovery and development. Beyond well-known RNA vaccines, antisense...
A fitness distribution law for amino-acid replacements.
The effect of replacing the amino acid at a given site in a protein is difficult to predict. Yet, evolutionary comparisons have revealed highly regular patterns of interchangeability between pairs...
A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV.
Anti-HIV envelope broadly neutralizing antibodies (bnAbs) are alternatives to conventional antiretrovirals with the potential to prevent and treat infection, reduce latent reservoirs, and/or...
Engineering GID4 for use as an N-terminal proline binder via directed evolution.
Nucleic acid sequencing technologies have gone through extraordinary advancements in the past several decades, significantly increasing throughput while reducing cost. To create similar...