10x Genomics’ Post

Ants may feel like unwanted housemates, but they’re actually pretty cool when you give them a chance. This #singlecell RNA-seq study revealed the specific cell type and gene expression programs driving the divergent physiology and behavior of foragers and soldiers in one ant species. Learn more in our blog!

🚀 Exciting research alert from APAC! 🧬 Using #Xenium, researchers in South Korea have validated single cell RNA sequencing datasets, shedding light on the embryonic development stages in mouse skin. By mapping the spatial distribution of key marker genes, they discovered unique molecular distinctions between upper and lower embryonic fibroblasts, confirmed the diversity in embryonic dermal fibroblasts, and identified major differentiation pathways in the perinatal dermis. This study even pinpointed potential key driver genes for each trajectory. 🔬 Why it matters: This comprehensive cellular transcriptomic atlas is a vital reference for future skin development and regeneration research. 📄 Read the full publication here: https://lnkd.in/gKaKmdXs

Welcome to Club Xenium! 🎉

Amazing discoveries happen when new technologies allow talented researchers to tackle the questions whose answers were previously inaccessible. For example, the D’Souza lab took advantage of the single cell spatial resolution of Xenium In Situ to understand the complex spatial regulation of cleft palate formation. Their findings could fuel the discovery of potential in utero and early postnatal therapeutic targets for correcting cleft palate anomalies, which affects ~1 in every 700 live births annually. Read our news release to learn more about the insights they uncovered: https://lnkd.in/gAJnQAAY

Every problem is unique, so every solution should be too. At 10x, we operate on first principles, so when we’re faced with a challenge, we don’t just ask, “How did we do it before?” We go deeper. We get to the root of the problem, and while we draw on our past knowledge and experiences, we always look for new and better ways to apply what we’ve learned. Watch our latest video to learn more about our company culture and see how we problem-solve. And if you’re finding that “We’ve always done it this way…” just isn’t cutting it, explore jobs here: https://bit.ly/3RJ2eV8 #WeAre10x

Technology impacts the reliability of your #singlecell data. An independently conducted study reported that our Chromium Flex and 3' assays outperformed other technologies. See how the others stacked up: https://lnkd.in/ejWXYpAd

Looks like the perfect box for hide and seq 👀

“To treat or not to treat” is a question that patients with precancerous #multiplemyeloma conditions and their physicians must tackle. Unfortunately, assessing risk of progression requires invasive methods with limited accuracy. A new project headed by the Foundation for the National Institutes of Health Biomarkers Consortium will use Chromium #singlecell assays to discover blood-based #biomarkers associated with #multiplemyeloma, offering hope for less invasive, more accurate risk assessment. Learn more: https://lnkd.in/gcg_kq35

A recent Nature Neuroscience publication from the Brain Mind Institute in Switzerland uses Single Cell ATAC + Gene Expression to explore cell fate progression in organoid models.

From the beginning, our co-founders have been driven to make a long-lasting impact far beyond providing innovative research tools. They continually strive to make sure these tools will help researchers make meaningful discoveries that have the potential to truly change lives. As our co-founder and Chief Scientific Officer, Ben Hindson, often reminds us, it is this mission of “Accelerating the mastery of biology to advance human health” that pushes 10xers to take on the hardest challenges. Read more about our co-founders’ commitment to innovation and advancing human health: https://lnkd.in/gRBdmWRj #TogetherWeInnovate