BRT Laboratories: Difference between revisions
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{{Short description|DNA sequencing laboratories}} |
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| ⚫ | '''BRT Laboratories, Inc.''' is a [[Baltimore]], Maryland-based [[biotechnology]] company that performs [[DNA profiling|DNA testing]]. The company has three divisions: Relationship Testing, [[Forensic science|Forensics]], and Clinical Services. It is a privately held, wholly owned [[subsidiary]] of Baltimore RH Typing Laboratory, Inc. |
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slogan = BRT Labs | |
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| ⚫ | '''BRT Laboratories, Inc.''' is a [[Baltimore]], Maryland |
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==History== |
==History== |
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BRT Laboratories, Inc, with its parent company Baltimore RH Typing Laboratory, has been a provider of products and services to the medical, research, and commercial communities since 1945. |
BRT Laboratories, Inc., with its parent company Baltimore RH Typing Laboratory, has been a provider of products and services to the medical, research, and commercial communities since 1945. In April 2000, BRT Laboratories, Inc. was established as an independent and wholly owned subsidiary of Baltimore Rh Typing Laboratory, Inc., for the purpose of continuing commercial testing and service activities. {{citation needed|date=October 2017}} |
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==Services== |
==Services== |
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===Relationship Testing=== |
===Relationship Testing=== |
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BRT's Relationship Testing division offers services in [[DNA paternity testing|Paternity Testing]] and [[Family reunification]] Immigration Testing. DNA testing can identify relationships between parent and child, full or half siblings, grandparent and grandchild, uncles or aunts and nieces or nephews, as well as identical and non-identical twins. The Laboratory is accredited by the [[AABB]] (formerly, American Association of Blood Banks).<ref>AABB Accredited Relationship Testing Facilities "http://www.aabb.org/Content/Accreditation/Parentage_Testing_Accreditation_Program/AABB_Accredited_Parentage_Testing_Laboratories/aboutptlabs.htm {{Webarchive|url=https://web.archive.org/web/20100131182905/http://www.aabb.org/Content/Accreditation/Parentage_Testing_Accreditation_Program/AABB_Accredited_Parentage_Testing_Laboratories/aboutptlabs.htm |date=2010-01-31 }}"</ref> Testing can be performed for submission in legal proceedings (court admissible) or for personal knowledge. |
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Application for immigration to the United States and Canada often requires documentation of biological relationship between a petitioner and his or her beneficiary. DNA testing can be used to prove a relationship if documents are absent or challenged. The US Immigration and Naturalization Service (INS) and United States Citizenship and Immigration Services (USCIS) offices accept DNA testing results from AABB accredited laboratories only.<ref>INS Memorandum on DNA Testing to Establish Family Relationships “http://www.immigrationlinks.com/news/news413.htm”</ref> |
Application for immigration to the United States and Canada often requires documentation of biological relationship between a petitioner and his or her beneficiary. DNA testing can be used to prove a relationship if documents are absent or challenged. The US Immigration and Naturalization Service (INS) and United States Citizenship and Immigration Services (USCIS) offices accept DNA testing results from AABB accredited laboratories only.<ref>INS Memorandum on DNA Testing to Establish Family Relationships “http://www.immigrationlinks.com/news/news413.htm”{{Dead link|date=June 2020 |bot=InternetArchiveBot |fix-attempted=yes }}</ref> |
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===Forensics=== |
===Forensics=== |
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BRT's Forensics division offers services in serology screening, DNA profiling, and case review. These services are contracted by government agencies, defense counsel, and private citizens or organizations for several applications. |
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Government agencies contract BRT’s Forensic division for criminal and “no-suspect” casework. The Laboratory offers [[STR analysis]] and [[Y-STR]] analysis with each of the commercial kits commonly used in the US. The Forensic division is accredited by ASCLD/Lab – International <ref>ASCLD/Lab |
Government agencies contract BRT’s Forensic division for criminal and “no-suspect” casework. The Laboratory offers [[STR analysis]] and [[Y-STR]] analysis with each of the commercial kits commonly used in the US. The Forensic division is accredited by ASCLD/Lab – International <ref>ASCLD/Lab "http://www.ascld-lab.org/international/indexinternational.html"</ref> and meets the requirements of ISO/IEC 17025. BRT has also received accreditation from the Texas Department of Public Safety and has been approved by the Maryland State Police Forensic Science Division for analysis of casework that can be uploaded to CODIS. The Laboratory adheres to current [https://web.archive.org/web/20091111045023/http://www.nfstc.org/pdi/Subject10/pdi_s10_m03_01_d.htm Scientific Working Group on DNA Analysis Methods] (SWGDAM) and [http://www.cstl.nist.gov/strbase/dabqas.htm FBI DNA Advisory Board (DAB)] guidelines. |
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Defense counsel contract BRT Laboratories to perform case reviews, which may include assistance with the interpretation of subpoena documents, sample retesting, and/or expert witness testimony. |
Defense counsel contract BRT Laboratories to perform case reviews, which may include assistance with the interpretation of subpoena documents, sample retesting, and/or expert witness testimony. |
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===Clinical Services=== |
===Clinical Services=== |
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BRT's Clinical Services division is licensed by the [http://www.dhmh.state.md.us/ State of Maryland Department of Health and Mental Hygiene] for Molecular Biology and Molecular Genetics and is registered under the US Department of Health and Human Services' [http://www.cms.hhs.gov/clia/ Clinical Laboratory Improvement Amendments.] Test offerings include [[Tuberculosis]] testing and Bone Marrow Engraftment [[chimera (genetics)|(chimerism)]] monitoring. |
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BRT’s tuberculosis (TB) testing is performed using the [[Interferon-gamma]] release assay [[T-SPOT.TB]]. This assay is recognized by the [[ |
BRT’s tuberculosis (TB) testing is performed using the [[Interferon-gamma]] release assay [[T-SPOT.TB]]. This assay is recognized by the [[Centers for Disease Control and Prevention]] as a special TB blood test <ref>CDC Tuberculosis Testing and Diagnosis https://www.cdc.gov/tb/topic/testing/default.htm</ref> with an accuracy of diagnosing active TB >80%.<ref>{{cite journal |vauthors=Wang JY, Chou CH, Lee LN, Hsu HL, Jan IS, Hsueh PR |title =Diagnosis of tuberculosis by an enzyme-linked immunospot assay for interferon-γ |journal=Emerg Infect Dis |volume=13 |issue=4 |date=April 2007|display-authors=etal |doi=10.3201/eid1304.051195|pmc=2725949 }} https://www.cdc.gov/EID/content/13/4/553.htm</ref> |
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Bone Marrow Engraftment monitoring assesses the relative ratio of donor and recipient cell populations in the post-transplant peripheral blood or bone marrow of the patient. BRT performs this test using STR analysis, the current "gold standard,"<ref>{{cite journal |author=Vnencak‐Jones C L |title=Bone Marrow Engraftment Studies |journal=Curr. Protoc. Hum. Genet. |issue=UNIT 9.17 |date=July 2009 |doi=10.1002/0471142905.hg0917s62}} http://www.currentprotocols.com/protocol/hg0917</ref> yielding a sensitivity of |
Bone Marrow Engraftment monitoring assesses the relative ratio of donor and recipient cell populations in the post-transplant peripheral blood or bone marrow of the patient. BRT performs this test using STR analysis, the current "gold standard,"<ref>{{cite journal |author=Vnencak‐Jones C L |title=Bone Marrow Engraftment Studies |journal=Curr. Protoc. Hum. Genet. |issue=UNIT 9.17 |date=July 2009 |doi=10.1002/0471142905.hg0917s62}} http://www.currentprotocols.com/protocol/hg0917 {{Webarchive|url=https://web.archive.org/web/20090620234642/http://www.currentprotocols.com/protocol/hg0917 |date=2009-06-20 }}</ref> yielding a sensitivity of 95–98%. |
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==Accreditations== |
==Accreditations== |
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==Locations== |
==Locations== |
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BRT is headquartered in Baltimore, |
BRT is headquartered in Baltimore, Maryland, with an extensive network of sample collection centers located across the United States and throughout the world. |
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==References== |
==References== |
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[[Category:Biotechnology companies established in 1945]] |
[[Category:Biotechnology companies established in 1945]] |
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[[Category:1945 establishments in Maryland]] |
[[Category:1945 establishments in Maryland]] |
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[[Category:Companies based in Baltimore]] |
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Latest revision as of 12:46, 16 March 2023
| Company type | Privately owned |
|---|---|
| Industry | Biotechnology |
| Founded | 1945 |
| Headquarters | Baltimore, MD , United States |
Key people | Robert E. Wenk, MD |
| Website | brtlabs.com |
BRT Laboratories, Inc. is a Baltimore, Maryland-based biotechnology company that performs DNA testing. The company has three divisions: Relationship Testing, Forensics, and Clinical Services. It is a privately held, wholly owned subsidiary of Baltimore RH Typing Laboratory, Inc.
History[edit]
BRT Laboratories, Inc., with its parent company Baltimore RH Typing Laboratory, has been a provider of products and services to the medical, research, and commercial communities since 1945. In April 2000, BRT Laboratories, Inc. was established as an independent and wholly owned subsidiary of Baltimore Rh Typing Laboratory, Inc., for the purpose of continuing commercial testing and service activities. [citation needed]
Services[edit]
Relationship Testing[edit]
BRT's Relationship Testing division offers services in Paternity Testing and Family reunification Immigration Testing. DNA testing can identify relationships between parent and child, full or half siblings, grandparent and grandchild, uncles or aunts and nieces or nephews, as well as identical and non-identical twins. The Laboratory is accredited by the AABB (formerly, American Association of Blood Banks).[1] Testing can be performed for submission in legal proceedings (court admissible) or for personal knowledge.
Application for immigration to the United States and Canada often requires documentation of biological relationship between a petitioner and his or her beneficiary. DNA testing can be used to prove a relationship if documents are absent or challenged. The US Immigration and Naturalization Service (INS) and United States Citizenship and Immigration Services (USCIS) offices accept DNA testing results from AABB accredited laboratories only.[2]
Forensics[edit]
BRT's Forensics division offers services in serology screening, DNA profiling, and case review. These services are contracted by government agencies, defense counsel, and private citizens or organizations for several applications.
Government agencies contract BRT’s Forensic division for criminal and “no-suspect” casework. The Laboratory offers STR analysis and Y-STR analysis with each of the commercial kits commonly used in the US. The Forensic division is accredited by ASCLD/Lab – International [3] and meets the requirements of ISO/IEC 17025. BRT has also received accreditation from the Texas Department of Public Safety and has been approved by the Maryland State Police Forensic Science Division for analysis of casework that can be uploaded to CODIS. The Laboratory adheres to current Scientific Working Group on DNA Analysis Methods (SWGDAM) and FBI DNA Advisory Board (DAB) guidelines.
Defense counsel contract BRT Laboratories to perform case reviews, which may include assistance with the interpretation of subpoena documents, sample retesting, and/or expert witness testimony.
The Forensic division also provides serology and DNA profiling services to private citizens for infidelity testing and to private organizations or medical professionals for sample identity verification.
Clinical Services[edit]
BRT's Clinical Services division is licensed by the State of Maryland Department of Health and Mental Hygiene for Molecular Biology and Molecular Genetics and is registered under the US Department of Health and Human Services' Clinical Laboratory Improvement Amendments. Test offerings include Tuberculosis testing and Bone Marrow Engraftment (chimerism) monitoring.
BRT’s tuberculosis (TB) testing is performed using the Interferon-gamma release assay T-SPOT.TB. This assay is recognized by the Centers for Disease Control and Prevention as a special TB blood test [4] with an accuracy of diagnosing active TB >80%.[5]
Bone Marrow Engraftment monitoring assesses the relative ratio of donor and recipient cell populations in the post-transplant peripheral blood or bone marrow of the patient. BRT performs this test using STR analysis, the current "gold standard,"[6] yielding a sensitivity of 95–98%.
Accreditations[edit]
- Member of and accredited by the American Association of Blood Banks (AABB)
- Registered by the Clinical Laboratory Improvement Amendments (CLIA)
- Licensed by the State of Maryland Department of Health & Mental Hygiene
- Licensed by the State of New York Department of Health
- 17025 and Forensic Requirements for Accreditation (FRA 1 and FRA 2)
- College of American Pathologists (CAP) Proficiency Participant
- American Society of Crime Laboratory Directors (ASCLD/LAB-International)
Locations[edit]
BRT is headquartered in Baltimore, Maryland, with an extensive network of sample collection centers located across the United States and throughout the world.
References[edit]
- ^ AABB Accredited Relationship Testing Facilities "http://www.aabb.org/Content/Accreditation/Parentage_Testing_Accreditation_Program/AABB_Accredited_Parentage_Testing_Laboratories/aboutptlabs.htm Archived 2010-01-31 at the Wayback Machine"
- ^ INS Memorandum on DNA Testing to Establish Family Relationships “http://www.immigrationlinks.com/news/news413.htm”[permanent dead link]
- ^ ASCLD/Lab "http://www.ascld-lab.org/international/indexinternational.html"
- ^ CDC Tuberculosis Testing and Diagnosis https://www.cdc.gov/tb/topic/testing/default.htm
- ^ Wang JY, Chou CH, Lee LN, Hsu HL, Jan IS, Hsueh PR, et al. (April 2007). "Diagnosis of tuberculosis by an enzyme-linked immunospot assay for interferon-γ". Emerg Infect Dis. 13 (4). doi:10.3201/eid1304.051195. PMC 2725949. https://www.cdc.gov/EID/content/13/4/553.htm
- ^ Vnencak‐Jones C L (July 2009). "Bone Marrow Engraftment Studies". Curr. Protoc. Hum. Genet. (UNIT 9.17). doi:10.1002/0471142905.hg0917s62. http://www.currentprotocols.com/protocol/hg0917 Archived 2009-06-20 at the Wayback Machine