Cafedrine (INN , BAN ), sold under the brand name Akrinor among others, is a chemical linkage of norephedrine and theophylline and is a cardiac stimulant and antihypotensive agent used to increase blood pressure in people with hypotension.[1][2][3][4] It has been marketed in Europe, South Africa, and Indonesia.[4][5]
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Trade names | Akrinor, Bifort, Praxinor |
Other names | Caphedrine; Cafedrin; Caphedrin; Kafedrin; Norephedrinoethyltheophylline; 7-(2-(β-Hydroxy-α-methylphenethylamino)ethyl)theophylline |
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Formula | C18H23N5O3 |
Molar mass | 357.414 g·mol−1 |
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There has been concern about cafedrine as a potential performance-enhancing drug and doping agent in sports.[6]
See also
editReferences
edit- ^ Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 205. ISBN 978-1-4757-2085-3. Retrieved 29 August 2024.
- ^ Pharmaceutical Manufacturing Encyclopedia. Volumes 1-4. Elsevier Science. 2013. p. 785. ISBN 978-0-8155-1856-3. Retrieved 29 August 2024.
- ^ Morton IK, Hall JM (1999). "Calcitonin gene-related peptide receptor antagonist". Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Dordrecht: Springer Netherlands. p. 59. ISBN 9789401144391.
- ^ a b Schweizerischer Apotheker-Verein (2000). Index Nominum 2000: International Drug Directory. Index nominum. Medpharm Scientific Publishers. p. 157. ISBN 978-3-88763-075-1. Retrieved 29 August 2024.
- ^ "Cafedrine". Drugs.com. Retrieved 29 August 2024.
- ^ Wilson W, Derse E (2001). Doping in Elite Sport: The Politics of Drugs in the Olympic Movement. Human Kinetics. p. 15. ISBN 978-0-7360-0329-2. Retrieved 29 August 2024.