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==== Native American (Mexico) uses ====
[[File:Nixtamalized Corn maize.jpg|thumb
In chewing [[coca leaves]], calcium hydroxide is usually chewed alongside to keep the [[alkaloid]] [[stimulant]]s chemically available for [[absorption (small intestine)|absorption]] by the body. Similarly, Native Americans traditionally chewed tobacco leaves with calcium hydroxide derived from burnt mollusc shells to enhance the effects. It has also been used by some indigenous American tribes as an ingredient in ''[[yopo]]'', a psychedelic snuff prepared from the beans of some ''[[Anadenanthera]]'' species.<ref>{{cite journal |author=de Smet, Peter A. G. M. |title=A multidisciplinary overview of intoxicating snuff rituals in the Western Hemisphere |doi=10.1016/0378-8741(85)90060-1 |pmid=3887041 |journal=Journal of Ethnopharmacology |volume=3 |issue=1 |year=1985 |pages=3–49}}</ref>
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