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Line 1: {{Short description\|1999 popular science book by Matt Ridley}} {{Infobox book \| name = Genome: The Autobiography of a Species in 23 Chapters Line 17 ⟶ 18: '''''Genome: The Autobiography of a Species in 23 Chapters''''' is a 1999 [[popular science]] [[book]] by the science writer [[Matt Ridley]], published by Fourth Estate. The chapters are numbered for the pairs of human [[chromosomes]], one pair being the X and Y [[sex chromosome]]s, so the numbering goes up to 22 with Chapter X and Y couched between Chapters 7 and 8. The book was welcomed by critics in journals such as ''[[Nature (journal)\|Nature]]'' and newspapers including ''[[The New York Times]]''.<ref name=Kealey/><ref name=Silver/> The ''[[London Review of Books]]'' however found the book "at once instructive and infuriating", as "his right-wing politics lead him to slant the implications of the research".<ref name=Coyne/> ==Context== Line 31 ⟶ 32: ;Chapter 2, Species Ridley discusses the history of human kind as a genetically distinct species. He compares the human genome to [[Common chimpanzee\|chimpanzee]]s, and ancestral [[primates]]. He also points out that until the 19th ~~Century~~century, most scholars believed that there were 24 sets of genes, not 23 as known today. ;Chapter 3, History Line 39 ⟶ 40: ;Chapter 4, Fate [[Huntington's ~~Corea~~chorea]] is used to discuss the use of a particular sequence on [[Chromosome Four]] to cause traumatic health consequences. The search for the chromosomal source of this and other related diseases is discussed through the work of [[Nancy Wexler]], someone who may have inherited the gene but who turns to scientific work to study it in others. ;Chapter 5, Environment Line 72 ⟶ 73: ;Chapter 11, Personality Ridley chooses the gene [[D4DR]] which codes for the manufacture of [[dopamine]] and is located on the short arm of [[chromosome 11]]. Interactions between dopamine, [[serotonin]] and other [[Serotonin\|serotonin neurochemistry]] are lightly covered. ;Chapter 12, Self-Assembly Line 104 ⟶ 105: ;Chapter 19, Prevention It might be possible to prevent or cure [[Alzheimer's disease]] and [[coronary heart disease]]. APO genes like APOE influence fat and cholesterol metabolism. The E4 allele of EPOE contributes to the plaque buildup of Alzheimer's. [[Genetic testing]] may help patients take early preventative action. ;Chapter 20, Politics