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Neutralizing antibody: Difference between revisions

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A '''neutralizing antibody''' ('''NAb''') is an [[antibody]] that defends a [[cell (biology)|cell]] from a [[pathogen]] or infectious particle by neutralizing any effect it has biologically. Neutralization renders the particle no longer infectious or pathogenic.<ref name="Def">{{cite web|url=http://www.biology-online.org/dictionary/Neutralizing_antibody|title=Neutralizing antibody|year=2008|publisher=Biology-Online|access-date=2009-07-04}}</ref><ref>{{Cite journal|last=Klasse|first=P. J.|date=2014-09-09|title=Neutralization of Virus Infectivity by Antibodies: Old Problems in New Perspectives|journal=Advances in Biology|volume=2014 |pages=1–24 |doi=10.1155/2014/157895 |pmid=27099867 |pmc=4835181 |language=en|doi-access=free }}</ref>
Neutralizing antibodies are part of the [[Humoral immunity|humoral]] response of the [[adaptive immune system]] against [[virus]]es, [[Pathogenic bacteria#Intracellular|intracellular bacteria]] and [[microbial toxin]]. By binding specifically to surface structures ([[antigen]]) on an infectious particle, neutralizing antibodies prevent the particle from interacting with its [[Host (biology)|host cells]] it might infect and destroy.
 
==Mechanism==