PNPLA3: Difference between revisions

An association between alcoholic liver disease in [[Caucasian race|caucasian]]s and variations in this gene has been confirmed. <ref name="stickel">{{cite web | title = Stickel Genetic determinants of alcoholic liver disease| url = https://www.ncbi.nlm.nih.gov/pubmed/22110053| accessdate = }}</ref> A mutation of isoleucine to methionine (I[ATC]>M[ATG]) SNP rs738409 has been confirmed to increase susceptibility to alcoholic liver disease and also to have effects in diabetes.<ref name="Romeo">{{cite web | title = Romeo The role of PNPLA3 in health and disease.| url = https://www.ncbi.nlm.nih.gov/pubmed/29935383| accessdate = }}</ref>