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Polystyrene sulfonate is usually supplied in either the sodium or calcium form. It is used as a [[potassium binder]] in acute and [[chronic kidney disease]] for people with [[hyperkalemia]] (abnormal high blood serum potassium levels).<ref>{{MedlinePlusEncyclopedia|001179|High potassium level}}</ref> However, it is unclear if it is beneficial and there is concern about possible side effects when it is combined with [[sorbitol]].<ref>{{cite journal | vauthors = Sterns RH, Rojas M, Bernstein P, Chennupati S | title = Ion-exchange resins for the treatment of hyperkalemia: are they safe and effective? | journal = Journal of the American Society of Nephrology | volume = 21 | issue = 5 | pages = 733–735 | date = May 2010 | pmid = 20167700 | doi = 10.1681/ASN.2010010079 | doi-access = free }}</ref>
Polystyrene sulfonates are given by mouth with a meal or [[rectal administration|rectally]]
==Side effects==
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