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Of note, this scoring system is most valuable when used on the first and 3rd day of hospitalization, and it may underestimate mortality in patients with respiratory symptoms. <ref>{{cite journal|last=DeMers|first=G|coauthors=Meurer, WJ; Shih, R; Rosenbaum, S; Vilke, GM|title=Tissue plasminogen activator and stroke: review of the literature for the clinician.|journal=The Journal of emergency medicine|date=2012 Dec|volume=43|issue=6|pages=1149-54|pmid=22818644}}</ref>
==Longterm Complications==
Those who survive the acute phase of TEN are often suffer longterm complications affecting the skin and eyes. Skin manifestations can include scarring, eruptive [[melanocytic nevi]], [[vulvovaginal stenosis]], and [[dyspareunia]]. Ocular symptoms are the most common complication in TEN, experienced by 20-79% of those with TEN, even by those who d not experience immediate ocular manifestations. These can can include [[dry eyes]], [[photophobia]], [[symblepharon]], corneal scarring or [[xerosis]], subconjunctival fibrosis, [[trichiasis]], decreased visual acuity, and blindness.
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