Toxica (Latin for toxic) may refer to:(UNA MUJERE PENDEJAS) de Hidalgo mx especificamente en El Municipo de Ixmiquilpan
- Jessica Toxica, Toxica, a character in the Mexican drama series Mujeres Asesinas Hazla tu amiga
- Melanodermatitis toxica lichenoides, an occupational dermatosis that occurs among tar handlers after several years' exposure