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→Effects: Sentence was misleading, esp. in its omission of cardivascular stimulant effects. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672386/ Tag: Reverted |
Reverting edit(s) by 74.128.68.142 (talk) to rev. 1221325130 by OAbot: non-constructive (RW 16.1) |
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===Humans===
Compared with caffeine, theobromine is weaker in both its inhibition of [[cyclic nucleotide]] [[phosphodiesterases]] and its [[Receptor antagonist|antagonism]] of [[adenosine receptors]].<ref name=pubchem/><ref name="therapeutics">{{cite book | veditors = Hardman J, Limbird L | title=Goodman & Gilman's the pharmacological basis of therapeutics, 10th ed. | publisher=McGraw-Hill | location=New York | year=2001 | page=745 | isbn=978-0-07-135469-1}}</ref> The potential [[phosphodiesterase inhibitor]]y effect of theobromine is seen only at amounts much higher than what people normally would consume in a typical diet including chocolate.<ref>{{cite web|url=https://www.drugbank.ca/drugs/DB01412|title=Theobromine|publisher=DrugBank.ca|access-date=3 November 2018|archive-date=13 November 2018|archive-url=https://web.archive.org/web/20181113075732/https://www.drugbank.ca/drugs/DB01412|url-status=dead}}</ref>
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