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Trimetazidine: Difference between revisions

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==Use as a performance-enhancing drug==
Although trimetazidine was already developed for medical use in the 1970s, it only became listed in the [[World Anti-Doping Agency]] (WADA) prohibited substances list under the category of "hormone and metabolic modulators" beginning in 2014,<ref>{{cite news |last1=Ritchie |first1=Hannah |last2=Ramsay |first2=George |title=Trimetazidine: Drug banned by WADA makes 'your heart work more efficiently' |url=https://www.cnn.com/2022/02/10/sport/trimetazidine-banned-drug-explainer-spt-intl/index.html |access-date=10 February 2022 |work=CNN |agency=CNN |publisher=CNN |date=10 February 2022}}</ref><ref>{{Cite web|url=https://cen.acs.org/analytical-chemistry/forensic-science/trimetazidine-banned-Olympic-competition/100/web/2022/02|access-date=2022-02-19|website=cen.acs.org|title=What is trimetazidine and why is it banned in Olympic competition?|date=17 February 2022|author=Howes, Laura|quote=Trimetazidine (TMZ) is the generic name for the chemical that acts as a vasodilator and was discovered over 50 years ago (1970s). TMZ is commonly prescribed in Europe and Russia where it is taken as a pill or in delayed-release tablets to treat angina as well as vertigo, tinnitus, and certain visual disturbances. Since 2014, WADA has classed TMZ as a prohibited substance.}}</ref> and its use is prohibited at all times "in- and out-of-competition."<ref>{{cite web |title=World Anti-Doping Code International Standard Prohibited List |url=https://www.wada-ama.org/sites/default/files/2022-01/2022list_final_en_0.pdf |publisher=World Anti-Doping Agency |date=1 January 2022}}</ref>
 
In 2014, Chinese Olympic champion swimmer [[Sun Yang]] tested positive for trimetazidine, which had been newly banned four months earlier and classified as a prohibited stimulant by WADA; Sun Yang and his doctor were not made aware of the changes to the use of the drug of which he was prescribed, and was consequently banned by the [[Chinese Swimming Association]] for three months.<ref>{{Cite web|date=2020-03-19|title=Chinese swimmer Sun Yang is being falsely punished|url=https://www.sportsintegrityinitiative.com/chinese-swimmer-sun-yang-is-being-falsely-punished/|access-date=2022-02-19|website=Sports Integrity Initiative|language=en-GB}}</ref>