[go: nahoru, domu]

Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Mutect misses some long indels #3298

Open
davidbenjamin opened this issue Jul 18, 2017 · 0 comments
Open

Mutect misses some long indels #3298

davidbenjamin opened this issue Jul 18, 2017 · 0 comments
Milestone

Comments

@davidbenjamin
Copy link
Contributor

Sometimes the signature of a long indel in a bam (before reassembly, that is) is long soft clips at the end of reads. If these soft clips are long and high quality we need to recognize them as compelling evidence of variation in Mutect's active region determination. Currently all soft clips are weighted about as heavily as SNVs, which is too little in the case of long soft clips.

@davidbenjamin davidbenjamin added this to the Mutect 3 milestone Jul 18, 2017
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant