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Adding bed file support #10

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bilgehannevruz opened this issue May 29, 2020 · 4 comments
Closed

Adding bed file support #10

bilgehannevruz opened this issue May 29, 2020 · 4 comments
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enhancement New feature or request

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@bilgehannevruz
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Hello,

It can be good if we can provide a bed file, to get a covered and not covered list of genes or regions.
For now, I am doing this via python however it is making the process very slow.

Best regards,

@telatin
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telatin commented May 29, 2020

Hi @bilgehannevruz, thanks for the feedback!
The ancestor of covtobed (called 'coverage'), did this, but it's old and the source is not available for licensing issues. The binary ships with the docker image and can be used like

coverage -i panel_02.bam -t target_regions.bed --bed > output.bed

Having this said, it's in our wish list to provide this functionality, but it won't happen in the immediate future, unfortunately.

@telatin telatin added the enhancement New feature or request label May 29, 2020
@telatin
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telatin commented Sep 8, 2020

We are testing a new version with bed support, but release is not imminent.

For the records I drafted a Python script to merge a GTF (or BED) and a covtobed-output (BED) here:
https://gist.github.com/telatin/82b4c51b7085dd0597659de0cf632d2a

@telatin telatin closed this as completed Sep 8, 2020
@bilgehannevruz
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@telatin

Thank you for the information and provided gist.

@telatin telatin reopened this Sep 23, 2020
@telatin
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telatin commented Sep 23, 2020

Quick update:
there is a "covtotarget" tool that can be applied downstream.

Info:
https://github.com/telatin/covtools/blob/master/README.md#covtotarget

Linux binary:
https://github.com/telatin/covtools/tree/master/release

@telatin telatin closed this as completed Dec 10, 2020
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