Expression of the Drosophila segment polarity genes is initiated by a pre-pattern of pair-rule
gene products and maintained by a network of regulatory interactions throughout several
stages of embryonic development. Analysis of a model of gene interactions based on
differential equations showed that wild-type expression patterns of these genes can be
obtained for a wide range of kinetic parameters, which suggests that the steady states are
determined by the topology of the network and the type of regulatory interactions between …