The Battle of Tippecanoe (/ˌtɪpikəˈnuː/ TIP-ee-kə-NOO) was fought on November 7, 1811, near present-day Lafayette, Indiana between United States forces led by Governor William Henry Harrison of the Indiana Territory and Native American warriors associated with the Shawnee leader Tecumseh. Tecumseh and his brother Tenskwatawa (commonly known as "The Prophet") were leaders of a confederacy of Native Americans from various tribes that opposed US expansion into Native territory. As tensions and violence increased, Governor Harrison marched with an army of about 1,000 men to disperse the confederacy's headquarters at Prophetstown, near the confluence of the Tippecanoe and Wabash Rivers.

Tecumseh, not yet ready to oppose the United States by force, was away recruiting allies when Harrison's army arrived. Tenskwatawa, a spiritual leader but not a military man, was in charge. Harrison camped near Prophetstown on November 6 and arranged to meet with Tenskwatawa the following day. Early the next morning, warriors from Prophetstown attacked Harrison's army. Although the outnumbered attackers took Harrison's army by surprise, Harrison and his men stood their ground for more than two hours. The Natives were ultimately repulsed when their ammunition ran low. After the battle, the Natives abandoned Prophetstown and Harrison's men burned it to the ground, destroyed the food supplies stored up for the winter, and returned home.