Dothan /ˈdoʊθən/ is a city in the southeastern corner of the U.S. state of Alabama, situated approximately 20 miles (32 km) west of the Georgia state line and 16 miles (26 km) north of Florida. It is the seat of Houston County, with portions extending into nearby Dale County and Henry County. Its name derives from Genesis 37:17: "let us go to Dothan." According to the 2010 census the city's population was 65,496.

Dothan is the principal city of the Dothan, Alabama metropolitan area, which encompasses all of Geneva, Henry, and Houston counties; the small portion that lies in Dale County is part of the Ozark Micropolitan Statistical Area. The combined population for the entire Dothan metropolitan area in 2010 was 145,639. The city serves as the main transportation and commercial hub for a significant part of southeastern Alabama, southwest Georgia, and nearby portions of the Florida Panhandle. Since approximately one-fourth of the U.S. peanut crop is produced nearby, with much of it being processed in the city, Dothan is sometimes referred to as "The Peanut Capital of the World". Dothan also hosts the annual National Peanut Festival at the dedicated "Peanut Festival Fairgrounds".