Ruth (or its variants) may refer to:

Places

In geography

In space

People

Surname

One Big Happy is a daily comic strip written and illustrated by Rick Detorie, detailing the daily adventures of a six-year-old girl named Ruthie. The strip also features her eight-year-old brother Joe, their parents Frank and Ellen, and their grandparents Nick and Rose, who live next door. The strip's title is a takeoff on the phrase, "One big happy family." It debuted on September 11, 1988. The strip takes place on Buena Vista Avenue and in an unspecified city based on Baltimore, Maryland, where the creator grew up. It is syndicated by Creators Syndicate.

The strip focuses on the daily lives of the children and their interactions with their family, friends and neighbors. Grandparents Nick and Rose are featured often, as they live next door and have a close relationship with the kids. Together they watch television, play cards, bake, and participate in imaginative games. Ruthie often visits the local public library for story hour with the Library Lady, and annoys her with ceaseless questions and variations on her own tales. At school Ruthie dodges the affections of occasionally seen classmate Buggy Crispino (who thinks of himself a ladies man and has even complimented Ruthie's mom on her appearance), argues with her snotty rich friend Cylene, and she and Joe play with their ditzy friend James, a poor (and usually dirty) kid who lives down the street.