Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse (Q24290693)

regulation of transcription, DNA-templated

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

M E Brunkow

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E W Jeffery

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K A Hjerrild

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B Paeper

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L B Clark

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S A Yasayko

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J E Wilkinson

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D Galas

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S F Ziegler

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F Ramsdell

The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome

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language of work or name

English

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publication date

January 2001

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published in

Nature Genetics

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volume

27

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issue

1

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page(s)

68-73

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cites work

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7 January 2021

Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes

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7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

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7 January 2021

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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7 January 2021

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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7 January 2021

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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7 January 2021

The mouse scurfy (sf) mutation is tightly linked to Gata1 and Tfe3 on the proximal X chromosome

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7 January 2021

A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation

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7 January 2021

A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1.

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7 January 2021

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7 January 2021

Long-range map of a 3.5-Mb region in Xp11.23-22 with a sequence-ready map from a 1.1-Mb gene-rich interval

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7 January 2021

DNA-binding properties and secondary structural model of the hepatocyte nuclear factor 3/fork head domain

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7 January 2021

Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

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7 January 2021

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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7 January 2021

Analysis of hepatocyte nuclear factor-3 beta protein domains required for transcriptional activation and nuclear targeting

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7 January 2021

Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins

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7 January 2021

Transcriptional regulation of T lymphocyte development and function

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7 January 2021

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

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7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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7 January 2021

A novel transcription factor, T-bet, directs Th1 lineage commitment

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7 January 2021

LKLF: A transcriptional regulator of single-positive T cell quiescence and survival

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7 January 2021

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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7 January 2021

The molecular basis of the sparse fur mouse mutation

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7 January 2021

Basic local alignment search tool

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7 January 2021

Prediction of complete gene structures in human genomic DNA

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7 January 2021

Loss-of-function mutations in a calcium-channel alpha1-subunit gene in Xp11.23 cause incomplete X-linked congenital stationary night blindness

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7 January 2021

An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness

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7 January 2021