A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB (Q24321775)

GOA release 2020-03-11

I-kappaB phosphorylation

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GOA release 2020-03-11

author name string

J A DiDonato

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M Hayakawa

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D M Rothwarf

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E Zandi

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M Karin

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

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language of work or name

English

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publication date

7 August 1997

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published in

Nature

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volume

388

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issue

6642

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page(s)

548-54

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cites work

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7 January 2021

The I kappa B proteins: members of a multifunctional family

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7 January 2021

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

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7 January 2021

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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7 January 2021

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

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7 January 2021

N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

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7 January 2021

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

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7 January 2021

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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7 January 2021

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

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7 January 2021

The ubiquitin system for protein degradation

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7 January 2021

In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

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7 January 2021

Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B

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7 January 2021

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

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7 January 2021

Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites

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7 January 2021

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

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7 January 2021

Gamma-phosphate-linked ATP-sepharose for the affinity purification of protein kinases. Rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase

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7 January 2021

Function and activation of NF-kappa B in the immune system

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7 January 2021

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

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7 January 2021

NF-kappa B: ten years after

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7 January 2021

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

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7 January 2021

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

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7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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7 January 2021

IRAK: a kinase associated with the interleukin-1 receptor

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7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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7 January 2021

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

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7 January 2021

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

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7 January 2021

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

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7 January 2021

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

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7 January 2021