TWINKLE Has 5' -> 3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein (Q24323366)

GOA release 2020-03-11

Twinkle mtDNA helicase

1 reference

5'-3' DNA helicase activity

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

1 reference

3

Maria Falkenberg

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author name string

Jenny A Korhonen

series ordinal

1

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Martina Gaspari

series ordinal

2

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language of work or name

English

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publication date

5 December 2003

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published in

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volume

278

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issue

49

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page(s)

48627-32

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cites work

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Does human mtDNA recombine?

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Identification of initiation sites for heavy-strand and light-strand transcription in human mitochondrial DNA

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Priming of human mitochondrial DNA replication occurs at the light-strand promoter

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A Novel Closed-Circular Mitochondrial DNA with Properties of a Replicating Intermediate

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The accessory subunit of Xenopus laevis mitochondrial DNA polymerase gamma increases processivity of the catalytic subunit of human DNA polymerase gamma and is related to class II aminoacyl-tRNA synthetases

21 January 2018

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The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance

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Human mitochondrial DNA polymerase holoenzyme: reconstitution and characterization

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Functional interactions of mitochondrial DNA polymerase and single-stranded DNA-binding protein. Template-primer DNA binding and initiation and elongation of DNA strand synthesis

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Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

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Diseases caused by nuclear genes affecting mtDNA stability

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Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis

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Asymmetric interactions of hexameric bacteriophage T7 DNA helicase with the 5'- and 3'-tails of the forked DNA substrate.

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Replication of animal mitochondrial DNA.

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Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA.

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Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication.

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The UL8 subunit of the herpes simplex virus type-1 DNA helicase-primase optimizes utilization of DNA templates covered by the homologous single-strand DNA-binding protein ICP8.

21 January 2018

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The UL8 Subunit of the Heterotrimeric Herpes Simplex Virus Type 1 Helicase-Primase Is Required for the Unwinding of Single Strand DNA-binding Protein (ICP8)-coated DNA Substrates

21 January 2018

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Replisome-mediated DNA replication.

21 January 2018

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In vitro replication of human mitochondrial DNA: accurate initiation at the origin of light-strand synthesis

21 January 2018

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Effects of the Xenopus laevis mitochondrial single-stranded DNA-binding protein on the activity of DNA polymerase gamma

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M306981200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12975372

1 reference

Consolidated OpenCitations Corpus – April 2017