MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expression (Q24633930)

5

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Annelies de Klein

4

object named as

Annelies de Klein

0 references

Ellen C. Zwarthoff

7

object named as

Ellen C Zwarthoff

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author name string

Magda A Meester-Smoor

1

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Marjolein J F W Janssen

2

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Gerard C Grosveld

3

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Hannie Douben

RTPrimerDB: the real-time PCR primer and probe database, major update 2006.

6

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language of work or name

English

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publication date

October 2008

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published in

Carcinogenesis

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volume

29

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issue

10

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page(s)

2025-34

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cites work

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MN1 overexpression is an important step in the development of inv(16) AML.

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High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics

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MN1-TEL, the product of the t(12;22) in human myeloid leukemia, immortalizes murine myeloid cells and causes myeloid malignancy in mice.

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BMI-1 is highly expressed in M0-subtype acute myeloid leukemia.

21 January 2018

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Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells

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Suppression of ARG kinase activity by STI571 induces cell cycle arrest through up-regulation of CDK inhibitor p18/INK4c.

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The MN1-TEL myeloid leukemia-associated fusion protein has a dominant-negative effect on RAR-RXR-mediated transcription

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12 December 2020

Expression of MAC-1 (CD11b) in acute myeloid leukemia (AML) is associated with an unfavorable prognosis

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12 December 2020

Trans-activation of heparanase promoter by ETS transcription factors

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Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality

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Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation

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12 December 2020