Production of the antimalarial drug precursor artemisinic acid in engineered yeast (Q22061873)

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19 January 2020

title

Production of the antimalarial drug precursor artemisinic acid in engineered yeast (English)

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19 January 2020

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amorpha-4,11-diene 12-monooxygenase activity

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Gene Ontology release 2020-05-02

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ChEBI release 2020-05-28

1

Dae-Kyun Ro

Dae-Kyun

Ro

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19 January 2020

14

Richmond

Sarpong

Richmond Sarpong

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19 January 2020

15

Jay D

Keasling

Jay D Keasling

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19 January 2020

Mario Ouellet

3

Mario

Ouellet

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19 January 2020

James Kirby

10

James

Kirby

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19 January 2020

Yoichiro Shiba

13

Yoichiro

Shiba

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19 January 2020

Eric M Paradise

2

Eric M

Paradise

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19 January 2020

Karl J Fisher

4

Karl J

Fisher

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19 January 2020

Karyn L Newman

5

Karyn L

Newman

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19 January 2020

John M Ndungu

6

John M

Ndungu

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19 January 2020

Kimberly A Ho

7

Kimberly A

Ho

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19 January 2020

Rachel A Eachus

8

Rachel A

Eachus

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Timothy S Ham

9

Timothy S

Ham

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Michelle C Y Chang

11

Michelle C Y

Chang

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Sydnor T Withers

12

Sydnor T

Withers

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19 January 2020

language of work or name

English

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publication date

1 April 2006

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19 January 2020

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19 January 2020

volume

440

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19 January 2020

issue

7086

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19 January 2020

page(s)

940-943

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Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward targets based on verbal autopsy

19 January 2020

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Malaria disaster in Africa

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Identification of an antimalarial synthetic trioxolane drug development candidate

21 January 2018

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Infectious diseases. Source of new hope against malaria is in short supply

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Total synthesis of qinghaosu

21 January 2018

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Molecular cloning, expression, and characterization of amorpha-4,11-diene synthase, a key enzyme of artemisinin biosynthesis in Artemisia annua L

21 January 2018

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Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

21 January 2018

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A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes

21 January 2018

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Dual activators of the sterol biosynthetic pathway of Saccharomyces cerevisiae: similar activation/regulatory domains but different response mechanisms.

21 January 2018

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Sesquiterpene lactones as taxonomic characters in the asteraceae

21 January 2018

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Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua

21 January 2018

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Basic local alignment search tool

21 January 2018

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Regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha) species: cDNA isolation, characterization, and functional expression of (-)-4S-limonene-3-hydroxylase and (-)-4S-limonene-6-hydroxylase

21 January 2018

1 reference

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Cloning, heterologous expression, and functional characterization of 5-epi-aristolochene-1,3-dihydroxylase from tobacco (Nicotiana tabacum).

21 January 2018

1 reference

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Suppression of a P450 hydroxylase gene in plant trichome glands enhances natural-product-based aphid resistance.

21 January 2018

1 reference

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Arabidopsis ent-kaurene oxidase catalyzes three steps of gibberellin biosynthesis

21 January 2018

1 reference

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The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway

21 January 2018

1 reference

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Yeast expression of animal and plant P450s in optimized redox environments

21 January 2018

1 reference

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21 January 2018

1 reference

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7 January 2021

Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04640

7 January 2021

Metabolic engineering to produce sesquiterpenes in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04640

7 January 2021

Revised assignment of 1H-NMR signals of artemisinic acid

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04640

7 January 2021

Identifiers

DOI

10.1038/NATURE04640

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16612385%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

19 January 2020

1006120611

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017