Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts (Q39610954)

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scientific article published on February 1999

Language	Label	Description	Also known as
English	Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts	scientific article published on February 1999

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

author name string

N Takuwa

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Y Fukui

2

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Europe PubMed Central

PMC publication ID

13 September 2017

Y Takuwa

3

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Europe PubMed Central

PMC publication ID

13 September 2017

language of work or name

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publication date

1 February 1999

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Europe PubMed Central

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13 September 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

13 September 2017

19

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Europe PubMed Central

PMC publication ID

13 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

1346-1358

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=116063

14 September 2017

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

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Phosphorylation and activation of p70s6k by PDK1

1 reference

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The insulin-induced signalling pathway leading to S6 and initiation factor 4E binding protein 1 phosphorylation bifurcates at a rapamycin-sensitive point immediately upstream of p70s6k

1 reference

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Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

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Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

1 reference

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Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

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Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

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Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways

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Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

1 reference

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

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Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo

1 reference

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Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

1 reference

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Direct association of p110 beta phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110 beta

1 reference

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

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The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

1 reference

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1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

1 reference

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

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Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression

1 reference

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Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

1 reference

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

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Multiple independent inputs are required for activation of the p70 S6 kinase

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

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Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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Rho Family GTPases Bind to Phosphoinositide Kinases

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Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

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Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

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Role of phosphatidylinositol kinase in PDGF receptor signal transduction

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells

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Protein kinase C-mediated bidirectional regulation of DNA synthesis, RB protein phosphorylation, and cyclin-dependent kinases in human vascular endothelial cells

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p70s6k function is essential for G1 progression

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https://pubmed.ncbi.nlm.nih.gov/9891068

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Dominant negative effect of the truncated p110 subunit of phosphatidylinositol-3 kinase

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Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system

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Lipid-Regulated Kinases: Some Common Themes at Last

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10.1128/MCB.19.2.1346

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Europe PubMed Central

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13 September 2017

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Europe PubMed Central

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13 September 2017

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Europe PubMed Central

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13 September 2017

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