The chemical repertoire of natural ribozymes (Q30309627)

16 June 2017

1 reference

title

The chemical repertoire of natural ribozymes (English)

1 reference

16 June 2017

0 references

1

Jennifer A Doudna

1 reference

16 June 2017

2

Thomas R Cech

1 reference

16 June 2017

language of work or name

English

0 references

publication date

1 July 2002

1 reference

16 June 2017

1 reference

16 June 2017

volume

418

1 reference

16 June 2017

issue

6894

1 reference

16 June 2017

page(s)

222-228

1 reference

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

16 June 2017

cites work

1 reference

7 January 2021

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

1 reference

7 January 2021

RNA-catalysed nucleotide synthesis

1 reference

7 January 2021

Ribozyme-catalysed amino-acid transfer reactions

1 reference

7 January 2021

Selection of RNA amide synthases

1 reference

7 January 2021

Novel RNA catalysts for the Michael reaction

1 reference

7 January 2021

Acyl-CoAs from coenzyme ribozymes

1 reference

7 January 2021

In vitro selection of functional nucleic acids

1 reference

7 January 2021

Imidazole rescue of a cytosine mutation in a self-cleaving ribozyme

1 reference

7 January 2021

RNA cleavage by a DNA enzyme with extended chemical functionality

1 reference

7 January 2021

Rational design of allosteric ribozymes

1 reference

7 January 2021

In vitro evolution suggests multiple origins for the hammerhead ribozyme

1 reference

7 January 2021

The hammerhead, hairpin and VS ribozymes are catalytically proficient in monovalent cations alone

1 reference

7 January 2021

Three-dimensional structure of a hammerhead ribozyme

1 reference

7 January 2021

The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage

1 reference

7 January 2021

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

1 reference

7 January 2021

The structural basis of hammerhead ribozyme self-cleavage

1 reference

7 January 2021

Capture and visualization of a catalytic RNA enzyme-product complex using crystal lattice trapping and X-ray holographic reconstruction

1 reference

7 January 2021

A pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reaction

1 reference

7 January 2021

A re-investigation of the thio effect at the hammerhead cleavage site

1 reference

7 January 2021

Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation.

1 reference

7 January 2021

Identification of the hammerhead ribozyme metal ion binding site responsible for rescue of the deleterious effect of a cleavage site phosphorothioate

1 reference

7 January 2021

Does a single metal ion bridge the A-9 and scissile phosphate groups in the catalytically active hammerhead ribozyme structure?

1 reference

7 January 2021

Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations.

1 reference

7 January 2021

The hammerhead cleavage reaction in monovalent cations

1 reference

7 January 2021

Crystal structure of a hepatitis delta virus ribozyme

1 reference

7 January 2021

Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis

1 reference

7 January 2021

Triple-strand formation in the homopurine:homopyrimidine DNA oligonucleotides d(G-A)4 and d(T-C)4

1 reference

7 January 2021

Formation of a stable triplex from a single DNA strand

1 reference

7 January 2021

RNAs with dual specificity and dual RNAs with similar specificity

1 reference

7 January 2021

Adenine protonation in domain B of the hairpin ribozyme

1 reference

7 January 2021

Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavage

1 reference

7 January 2021

General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme

1 reference

7 January 2021

Proton inventory of the genomic HDV ribozyme in Mg(2+)-containing solutions.

1 reference

7 January 2021

Direct pK(a) measurement of the active-site cytosine in a genomic hepatitis delta virus ribozyme

1 reference

7 January 2021

Mechanistic characterization of the HDV genomic ribozyme: assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanism

1 reference

7 January 2021

A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavage

1 reference

7 January 2021

An unusual pH-independent and metal-ion-independent mechanism for hairpin ribozyme catalysis

1 reference

7 January 2021

The hairpin ribozyme: structure, assembly and catalysis

1 reference

7 January 2021

Mechanistic aspects of enzymatic catalysis: lessons from comparison of RNA and protein enzymes

1 reference

7 January 2021

Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction

1 reference

7 January 2021

Crystal structure of a group I ribozyme domain: principles of RNA packing

1 reference

7 January 2021

Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions

1 reference

7 January 2021

A preorganized active site in the crystal structure of the Tetrahymena ribozyme

1 reference

7 January 2021

Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis

1 reference

7 January 2021

An important base triple anchors the substrate helix recognition surface within the Tetrahymena ribozyme active site

1 reference

7 January 2021

Kinetic characterization of the second step of group II intron splicing: role of metal ions and the cleavage site 2'-OH in catalysis

1 reference

7 January 2021

Metal ion binding sites in a group II intron core

1 reference

7 January 2021

Metal ion coordination by the AGC triad in domain 5 contributes to group II intron catalysis

1 reference

7 January 2021

Identification of structural elements critical for inter-domain interactions in a group II self-splicing intron

1 reference

7 January 2021

A tertiary interaction that links active-site domains to the 5' splice site of a group II intron

1 reference

7 January 2021

Control of branch-site choice by a group II intron

1 reference

7 January 2021

Structural insights into group II intron catalysis and branch-site selection

1 reference

7 January 2021

A three-dimensional perspective on exon binding by a group II self-splicing intron

1 reference

7 January 2021

Visualizing the solvent-inaccessible core of a group II intron ribozyme

1 reference

7 January 2021

Efficient integration of an intron RNA into double-stranded DNA by reverse splicing

1 reference

7 January 2021

Ribonuclease P: unity and diversity in a tRNA processing ribozyme

1 reference

7 January 2021

The final cut. The importance of tRNA 3'-processing.

1 reference

7 January 2021

Role of metal ions in the hydrolysis reaction catalyzed by RNase P RNA from Bacillus subtilis

1 reference

7 January 2021

Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage

1 reference

7 January 2021

Three-dimensional working model of M1 RNA, the catalytic RNA subunit of ribonuclease P from Escherichia coli

1 reference

7 January 2021

Phylogenetic-comparative analysis of the eukaryal ribonuclease P RNA.

1 reference

7 January 2021

Eukaryotic ribonuclease P: increased complexity to cope with the nuclear pre-tRNA pathway

1 reference

7 January 2021

Two-metal-Ion catalysis in adenylyl cyclase

1 reference

7 January 2021

Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin

1 reference

7 January 2021

Exposing the kinetic traps in RNA folding

1 reference

7 January 2021

Maximizing RNA folding rates: a balancing act.

1 reference

7 January 2021

Early events in RNA folding

1 reference

7 January 2021

Beyond kinetic traps in RNA folding

1 reference

7 January 2021

A Single-Molecule Study of RNA Catalysis and Folding

1 reference

7 January 2021

Reversible unfolding of single RNA molecules by mechanical force

1 reference

7 January 2021

Exploring the folding landscape of a structured RNA

1 reference

7 January 2021

A tyrosyl-tRNA synthetase protein induces tertiary folding of the group I intron catalytic core

1 reference

7 January 2021

Assembly of a ribonucleoprotein catalyst by tertiary structure capture

1 reference

7 January 2021

An RNA conformational change between the two chemical steps of group II self-splicing.

1 reference

7 January 2021

Guanosine binds to the Tetrahymena ribozyme in more than one step, and its 2'-OH and the nonbridging pro-Sp phosphoryl oxygen at the cleavage site are required for productive docking

1 reference

7 January 2021

Folding of the hairpin ribozyme in its natural conformation achieves close physical proximity of the loops

1 reference

7 January 2021

Rearrangement of a stable RNA secondary structure during VS ribozyme catalysis

1 reference

7 January 2021

Unusual resistance of peptidyl transferase to protein extraction procedures

1 reference

7 January 2021

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

1 reference

7 January 2021

An inhibitor of ribosomal peptidyl transferase using transition-state analogy

1 reference

7 January 2021

The structural basis of ribosome activity in peptide bond synthesis

1 reference

7 January 2021

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide

1 reference

7 January 2021

Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit

1 reference

7 January 2021

RNA-catalyzed amino acid activation

1 reference

7 January 2021

Specific, rapid synthesis of Phe-RNA by RNA.

1 reference

7 January 2021

A tiny RNA that catalyzes both aminoacyl-RNA and peptidyl-RNA synthesis

1 reference

7 January 2021

The question remains: is the spliceosome a ribozyme?

1 reference

7 January 2021

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

1 reference

7 January 2021

1 reference

7 January 2021

Identifiers

DOI

10.1038/418222A

1 reference

16 June 2017

1 reference