Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid (Q33802661)

29 July 2017

title

Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid (English)

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29 July 2017

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Rachel E Rigby

11

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Johannes N Spelbrink

Johannes N Spelbrink

13

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Ian Holt

Ian J Holt

17

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Howard Jacobs

Howard T Jacobs

16

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Andrew Jackson

Andrew P Jackson

12

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Smaranda Willcox

10

Smaranda Willcox

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29 July 2017

8

Tricia J Cluett

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29 July 2017

9

Steffi Goffart

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29 July 2017

author name string

Jaakko L O Pohjoismäki

1

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29 July 2017

J Bradley Holmes

2

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29 July 2017

Stuart R Wood

3

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29 July 2017

Ming-Yao Yang

4

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29 July 2017

Takehiro Yasukawa

5

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29 July 2017

Aurelio Reyes

6

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29 July 2017

Laura J Bailey

7

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29 July 2017

Jack D Griffith

14

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29 July 2017

Robert J Crouch

15

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29 July 2017

language of work or name

English

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publication date

23 February 2010

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Journal of Molecular Biology

29 July 2017

published in

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29 July 2017

volume

397

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29 July 2017

issue

5

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29 July 2017

page(s)

1144-1155

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Native R-loops persist throughout the mouse mitochondrial DNA genome

29 July 2017

cites work

1 reference

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RNase H activity: structure, specificity, and function in reverse transcription

4 July 2018

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Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes.

4 July 2018

1 reference

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Replication fork regression in repetitive DNAs

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

A bidirectional origin of replication maps to the major noncoding region of human mitochondrial DNA.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Revisiting the mouse mitochondrial DNA sequence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Structure of a T7 RNA polymerase elongation complex at 2.9 A resolution

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Eukaryotic ribonucleases HI and HII generate characteristic hydrolytic patterns on DNA-RNA hybrids: further evidence that mitochondrial RNase H is an RNase HII.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Two-dimensional gel analysis of rolling circle replication in the presence and absence of bacteriophage T4 primase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Analysis of replication intermediates by two-dimensional agarose gel electrophoresis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Autonomous replication in human cells of multimers of specific human and bacterial DNA sequences

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Replication of animal mitochondrial DNA.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

The presence of RNA in a double helix inhibits its interaction with histone protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Replicating molecules of circular mitochondrial DNA

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Electron-microscopic visualization of deletion mutations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Replication of Mitochondrial DNA in Mouse L Cells and Their Thymidine Kinase - Derivatives: Displacement Replication on a Covalently-Closed Circular Template

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Replication of mitochondrial DNA. Circular replicative intermediates in mouse L cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Single strand-containing replicating molecules of circular mitochondrial DNA.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Ultracentrifuge and electron microscope studies on the structure of mitochondrial DNA.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

The presence of ribonucleotides in mature closed-circular mitochondrial DNA.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

The complete nucleotide sequence of the Rattus norvegicus mitochondrial genome: cryptic signals revealed by comparative analysis between vertebrates

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Characterization of monoclonal antibody to DNA.RNA and its application to immunodetection of hybrids

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Electron microscopic visualization of DNA and DNA-protein complexes as adjunct to biochemical studies

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Studies on the product binding sites of the Azotobacter vinelandii ribonucleic acid polymerase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Nucleotide sequence of a region of human mitochondrial DNA containing the precisely identified origin of replication

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Mammalian mitochondrial DNA replicates bidirectionally from an initiation zone

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857715

40 Isolation of mammalian mitochondrial DNA and RNA and cloning of the mitochondrial genome

30 October 2018

1 reference

12 December 2020

Multiple mechanisms for initiation of ColE1 DNA replication: DNA synthesis in the presence and absence of ribonuclease H

1 reference

12 December 2020

Bidirectional replication initiates at sites throughout the mitochondrial genome of birds

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12 December 2020

The mitochondrial DNA replication bubble has not burst

1 reference

12 December 2020

10.1016/J.JMB.2010.02.029

Identifiers

DOI

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29 July 2017

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29 July 2017

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