Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model (Q47115693)

http://europepmc.org/abstract/PMC/5728394

8 January 2018

title

Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model (English)

1 reference

http://europepmc.org/abstract/PMC/5728394

8 January 2018

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1

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7 June 2020

Greg Elgar

10

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Martin S. Taylor

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7 June 2020

Ian Holt

13

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Martin A.M. Reijns

14

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Antonella Spinazzola

15

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author name string

Lilian E Hunt

3

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7 June 2020

Takehiro Yasukawa

4

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Robert Young

5

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7 June 2020

Aleck W E Jones

6

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7 June 2020

Kaalak Reddy

7

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7 June 2020

Radha Desai

8

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Sam Virtue

9

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7 June 2020

Peter Voshol

11

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Ilaria Dalla Rosa

2

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7 June 2020

language of work or name

English

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publication date

2 November 2017

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http://europepmc.org/abstract/PMC/5728394

8 January 2018

published in

Nucleic Acids Research

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7 June 2020

volume

45

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7 June 2020

issue

22

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7 June 2020

page(s)

12808-12815

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Creative Commons Attribution 4.0 International

7 June 2020

copyright license

start time

1 November 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA.

1 reference

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Structural Impact of Single Ribonucleotide Residues in DNA

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MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria

23 May 2018

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Genome-wide mapping of embedded ribonucleotides and other noncanonical nucleotides using emRiboSeq and EndoSeq.

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Deoxyribonucleotide metabolism, mutagenesis and cancer

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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

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transparent, a gene affecting stripe formation in Zebrafish, encodes the mitochondrial protein Mpv17 that is required for iridophore survival

23 May 2018

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MPV17 Mutations Causing Adult-Onset Multisystemic Disorder With Multiple Mitochondrial DNA Deletions

23 May 2018

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Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

23 May 2018

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MPV17 mutation causes neuropathy and leukoencephalopathy with multiple mtDNA deletions in muscle.

23 May 2018

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Ribonucleotide discrimination and reverse transcription by the human mitochondrial DNA polymerase.

23 May 2018

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Nucleoside triphosphate pool asymmetry in mammalian mitochondria

23 May 2018

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23 May 2018

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Early-onset liver mtDNA depletion and late-onset proteinuric nephropathy in Mpv17 knockout mice

23 May 2018

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Analyzing real-time PCR data by the comparative C(T) method

23 May 2018

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Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

23 May 2018

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MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion

23 May 2018

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23 May 2018

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The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA

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23 May 2018

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23 May 2018

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23 May 2018

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15 August 2018

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Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication.

15 August 2018

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15 August 2018

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Mechanism of mitochondrial DNA replication in mouse L-cells: Kinetics of synthesis and turnover of the initiation sequence

3 November 2018

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12 December 2020

Nucleotide assignment of alkali-sensitive sites in mouse mitochondrial DNA

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12 December 2020

Ribonucleotides in closed circular mitochondrial DNA from HeLa cells

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12 December 2020

Mitochondrial diseases

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKX1009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29106596%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29106596%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

29106596

1 reference