Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating (Q41992885)

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scientific article published on November 1995

Language	Label	Description	Also known as
English	Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating	scientific article published on November 1995

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

author name string

M P Scheid

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

R W Lauener

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

V Duronio

3

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

language of work or name

0 references

publication date

1 November 1995

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

312 ( Pt 1)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

159-162

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

An evolutionary perspective on apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

1 reference

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5 June 2018

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

1 reference

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5 June 2018

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

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Mechanisms and genes of cellular suicide

1 reference

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5 June 2018

Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors

1 reference

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

1 reference

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5 June 2018

Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

The Fas death factor

1 reference

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5 June 2018

Product of the steel locus suppresses apoptosis in hemopoietic cells. Comparison with pathways activated by granulocyte macrophage colony-stimulating factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Tyrosine phosphorylation of receptor beta subunits and common substrates in response to interleukin-3 and granulocyte-macrophage colony-stimulating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Multiple hemopoietic growth factors stimulate activation of mitogen-activated protein kinase family members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Granulocyte-macrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

Membrane Ig cross-linking regulates phosphatidylinositol 3-kinase in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

5 June 2018

p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein

1 reference

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5 June 2018

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136239

18 August 2018

Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/7492306

12 December 2020

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Interleukin-4-dependent proliferation dissociates p44erk-1, p42erk-2, and p21ras activation from cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/7492306

12 December 2020

based on heuristic

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Multiple hemopoietins, with the exception of interleukin-4, induce modification of Shc and mSos1, but not their translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7492306

12 December 2020

based on heuristic

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Checkpoints of dueling dimers foil death wishes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7492306

12 December 2020

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inferred from PubMed ID database lookup

Wortmannin inhibits mitogen-activated protein kinase activation induced by platelet-activating factor in guinea pig neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/7492306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of protein kinase C and the Na+/H+ antiporter in suppression of apoptosis by granulocyte macrophage colony-stimulating factor and interleukin-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/7492306

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Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7492306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3120159

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

ResearchGate publication ID

0 references

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