Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains (Q43259456)

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scientific article published on 18 October 2009

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English	Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains	scientific article published on 18 October 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

title

Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains (English)

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

author

Eric Rubinstein

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10

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

An Staes

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An Staes

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7

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Claude Boucheix

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Claude Boucheix

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11

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Piet Herdewijn

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Piet Herdewijn

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6

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Bart De Strooper

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13

object named as

Bart De Strooper

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

author name string

Tomoko Wakabayashi

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1

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

Katleen Craessaerts

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2

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

Leen Bammens

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3

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

Mostafa Bentahir

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PubMed publication ID

19838174

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17 November 2017

Filip Borgions

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5

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

Evy Timmerman

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PubMed publication ID

19838174

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17 November 2017

Joël Vandekerckhove

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PubMed publication ID

19838174

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17 November 2017

Kris Gevaert

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12

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

publication date

18 October 2009

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

published in

Nature Cell Biology

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

volume

11

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

issue

11

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Europe PubMed Central

PubMed publication ID

19838174

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17 November 2017

page(s)

1340-1346

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PubMed publication ID

19838174

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17 November 2017

cites work

Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1038%2FNCB1978

retrieved

21 January 2018

Functional organization of the yeast proteome by systematic analysis of protein complexes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin diversifies its portfolio.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of signal peptide peptidase, a presenilin-type aspartic protease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution of gamma-secretase activity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

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inferred from PubMed ID database lookup

Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of presenilin cofactors in the gamma-secretase complex

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetraspanins.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of the human gamma-secretase complex

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta1 integrins show specific association with CD98 protein in low density membranes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of tetraspanin proteins--potential benefits and strategies

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S-palmitoylation of gamma-secretase subunits nicastrin and APH-1

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cell biological perspective on Alzheimer's disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A complex interaction pattern of CIS and SOCS2 with the leptin receptor

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lateral organization of membrane proteins: tetraspanins spin their web.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol contributes to the organization of tetraspanin-enriched microdomains and to CD81-dependent infection by malaria sporozoites

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel family of presenilin homologues

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of prototype transmembrane 4 superfamily protein complexes and their relation to lipid rafts

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetraspanin functions and associated microdomains

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19838174

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCB1978

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19838174

retrieved

17 November 2017

PubMed publication ID

19838174

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19838174

retrieved

17 November 2017

 

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