The INK4a/ARF tumor suppressor: one gene--two products--two pathways (Q77362259)

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5 December 2019

review article

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title

The INK4a/ARF tumor suppressor: one gene--two products--two pathways (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9757829%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

author name string

L Chin

series ordinal

1

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5 December 2019

J Pomerantz

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9757829%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

R A DePinho

series ordinal

3

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5 December 2019

publication date

1 August 1998

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5 December 2019

number of pages

6

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Trends in Biochemical Sciences

inferred from page(s)

published in

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5 December 2019

volume

23

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5 December 2019

issue

8

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5 December 2019

page(s)

291-296

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5 December 2019

cites work

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

G1 events and regulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

1 reference

7 January 2021

Retinoblastoma protein switches the E2F site from positive to negative element

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Transcriptional repression. The cancer-chromatin connection

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Absence of p53 gene mutations in cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Lack of p53 mutations and loss of heterozygosity in non-cultured human melanocytic lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

MDM2--arbiter of p53's destruction

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Cell-cycle regulators and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Cdk inhibitors in development and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Germline p16 mutations in familial melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

Intragenic mutations of the p16(INK4), p15(INK4B) and p18 genes in primary non-small-cell lung cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2898%2901236-5

7 January 2021

10.1016/S0968-0004(98)01236-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9757829%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference