RAB15

RAB15
Identifiers
Aliases	RAB15, member RAS oncogene family
External IDs	MGI: 1916865; HomoloGene: 131279; GeneCards: RAB15; OMA:RAB15 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) Band 14q23.3 Start 64,945,814 bp End 64,973,226 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12|12 C3 Start 76,844,734 bp End 76,869,682 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum right frontal lobe prefrontal cortex dorsolateral prefrontal cortex Brodmann area 9 cingulate gyrus anterior cingulate cortex endothelial cell parotid gland primary visual cortex Top expressed in vestibular membrane of cochlear duct transitional epithelium of urinary bladder visual cortex submandibular gland primary visual cortex dentate gyrus of hippocampal formation granule cell superior frontal gyrus lacrimal gland olfactory tubercle piriform cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding protein binding GTPase activity Cellular component cytoplasm perinuclear region of cytoplasm plasma membrane endosome membrane extracellular exosome membrane cilium endosome synaptic vesicle Biological process protein transport positive regulation of regulated secretory pathway vesicle docking involved in exocytosis protein secretion transport intracellular protein transport regulation of exocytosis Rab protein signal transduction protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 376267 104886 Ensembl ENSG00000139998 ENSMUSG00000021062 UniProt P59190 Q8K386 RefSeq (mRNA) NM_001308154 NM_198686 NM_001330182 NM_134050 NM_001347405 NM_001347406 NM_001347407 RefSeq (protein) NP_001295083 NP_001317111 NP_941959 n/a Location (UCSC) Chr 14: 64.95 – 64.97 Mb Chr 12: 76.84 – 76.87 Mb PubMed search
Wikidata
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Ras-related protein Rab-15 is a protein that in humans is encoded by the RAB15 gene.

Further reading

• Zuk PA, Elferink LA (1999). "Rab15 mediates an early endocytic event in Chinese hamster ovary cells". J. Biol. Chem. 274 (32): 22303–12. doi:10.1074/jbc.274.32.22303. PMID 10428799.
• Zuk PA, Elferink LA (2000). "Rab15 differentially regulates early endocytic trafficking". J. Biol. Chem. 275 (35): 26754–64. doi:10.1074/jbc.M000344200. PMID 10837464.
• Strick DJ, Francescutti DM, Zhao Y, Elferink LA (2002). "Mammalian suppressor of Sec4 modulates the inhibitory effect of Rab15 during early endocytosis". J. Biol. Chem. 277 (36): 32722–9. doi:10.1074/jbc.M205101200. PMID 12105226.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. Bibcode:2003Natur.421..601H. doi:10.1038/nature01348. PMID 12508121.
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strick DJ, Elferink LA (2006). "Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment". Mol. Biol. Cell. 16 (12): 5699–709. doi:10.1091/mbc.E05-03-0204. PMC 1289414. PMID 16195351.