Butein
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| Names | |
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| IUPAC name
(E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
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| Other names
2',3,4,4'-Tetrahydroxychalcone
2',4',3,4-Tetrahydroxychalcone 3,4,2',4'-Tetrahydroxychalcone 2′,4′,3,4-Tetrahydroxychalcone | |
| Identifiers | |
3D model (JSmol)
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| ECHA InfoCard | 100.006.963 |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C15H12O5 | |
| Molar mass | 272.25 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Butein is a chalcone. It can be found in Toxicodendron vernicifluum (or formerly Rhus verniciflua). It has antioxidative, aldose reductase and advanced glycation endproducts inhibitory effects[1]. It is also a sirtuin-activating compound, a chemical compound having an effect on sirtuins, a group of enzymes that use NAD+ to remove acetyl groups from proteins.
References
- ^ Lee EH, Song DG, Lee JY, Pan CH, Um BH, Jung SH (2008). "Inhibitory effect of the compounds isolated from Rhus verniciflua on aldose reductase and advanced glycation endproducts". Biol. Pharm. Bull. 31 (8): 1626–30. PMID 18670102.
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