Azalanstat
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Formula | C22H24ClN3O2S |
Molar mass | 429.96 g·mol−1 |
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Azalanstat (INN,[1] codenamed RS-21607) is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor.[2][3]
References
[edit]- ^ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 36" (PDF). World Health Organization. p. 141. Retrieved 3 January 2017.
- ^ Walker KA, Kertesz DJ, Rotstein DM, Swinney DC, Berry PW, So OY, et al. (July 1993). "Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering". Journal of Medicinal Chemistry. 36 (15): 2235–7. doi:10.1021/jm00067a022. PMID 8340925.
- ^ Burton PM, Swinney DC, Heller R, Dunlap B, Chiou M, Malonzo E, et al. (August 1995). "Azalanstat (RS-21607), a lanosterol 14 alpha-demethylase inhibitor with cholesterol-lowering activity". Biochemical Pharmacology. 50 (4): 529–44. doi:10.1016/0006-2952(95)00152-p. PMID 7646560.