Lisitsyn or Lisitsin (Russian: Лисицын, from лисица meaning fox) is a Russian masculine surname; its feminine counterpart is Lisitsyna or Lisitsina. It may refer to:
- Lisitsyns, Russian family of samovar-makers, metalworkers and businesspeople
- Aleksandr Ivanovich Lisitsyn (1901–1975), Soviet general
- Anatoly Lisitsyn (born 1947), Russian statesman
- Anna Lisitsyna (1922 – 1942), Hero of the Soviet Union
- Dmitry Lisitsyn, Russian environmentalist
- Georgy Lisitsin (1909–1972), Russian chess player
- Vladimir Lisitsin (1938–1971), Soviet football player
- Yevhen Lysytsyn (born 1981), Ukrainian football player