Talk:Northern epilepsy syndrome

note

This topic is being edited as an assignment in an undergraduate neurobiology course. The course is participating in the Wikipedia Education Program.

== Note to Reviewers ==--Jordannetts (talk) 03:57, 8 April 2014 (UTC) Northern Epilepsy Syndrome is a rare disease that only affects those of Finnish decent. Research was done primarily in the early 1990's but has just recently been looked into again (November 2013). However, limited amount of secondary sources are available because so much is still unknown.Kkakes728 (talk) 01:15, 25 March 2014 (UTC)--Sydval612 (talk) 18:57, 24 April 2014 (UTC)

Secondary Review: Overall, I think you did a great job on the article. It is short, however, based on the minimal information that is available, the article gives a great overview of the disease. I thought it was interesting that this disease has only been found in Finland. Also, it was interesting to learn that these seizures lead to mental retardation, especially during puberty. One recommendation would be to move the "History" section so that it is before the "Characteristics" section. This may create good introduction for the rest of the article. In addition, I recommend adding a few more links to the article. For example, the reader may gain a better understand of the disease if terms such as "seizure," "recessive autosomal mutation," and "Sanger Sequencing" were linked to articles describing these terms. Also, a pertinent picture may enhance the article. I really liked the reference box in the top right of the article. This gives the reader quick access to the specific classifications of the disease. Great job! Smorrissey7 (talk) 18:06, 26 March 2014 (UTC)

Disease pages on Wikipedia are to follow a specific layout with history at the end, but we agree that moving the history section to the beginning of the article would provide better context for the reader, and thus, this change has been made. As many links as possible have been made with additional explanations to further but briefly explain topics of the disease. No readily available images of the gene mutation were available for use on this page. Other pictures would not enhance the article.--Sydval612 (talk) 18:57, 24 April 2014 (UTC)

Secondary Review: Good article. It was short, but that seems to be due to the lack of research on a very rare disease. It would make the page flow better if the history section was the first section after the introduction. It would also help if there was a picture or two, especially one in the info box, although if there wasn't any that were usable that wouldn't surprise me. Beyond that, I didn't see anything that was worded confusingly or poorly. It seems like a very good article. Zxdsqw (talk) 21:25, 4 April 2014 (UTC)

Disease pages on Wikipedia are to follow a specific layout with history at the end, but we agree that moving the history section to the beginning of the article would provide better context for the reader, and thus, this change has been made. No readily available images of the gene mutation were available for use on this page. Other pictures would not enhance the article.--Sydval612 (talk) 18:57, 24 April 2014 (UTC)

Secondary Review: Despite the lack of relevant, and abundant, research available, your article presents itself as informative and 'to the point'. This topic was fascinating, especially due to the isolation for which the disorder is found. Being said, I have just a few suggestions for you in a format that directs you to the specific tabs:

• Early Childhood: change the last sentence to read: “In the years following the onset of seizure, there is a noticeable decrease in intellectual capacity.” With that, I am interested in knowing what type of intellectual capacitance is degraded at this stage (i.e., memory formation).
• Adolescence: The second sentence is oddly written; however, it presents important information. I suggest rewriting it.
• Genetic Causes: Avoid using quotation marks and paraphrase what the original author(s) was demonstrating.

Again, nice job on your page, and I look forward to seeing your final product. MU Senior2014 (talk) 03:44, 5 April 2014 (UTC)

Unfortunately, not much more information could be added to these sections because this level of detail was unavailable to us. We were able to elaborate on other sections when we could, using the sources available to us. --Sydval612 (talk) 18:57, 24 April 2014 (UTC)

Secondary Review: Even though there was limited amount of information for your article, you managed to write a short and concise article. I find really interesting that this disease has only been reported in Finland. Overall, the article is well written and has sufficient information for the reader to have a good understanding of what northern epilepsy syndrome is. I would still add a couple of extra hyperlinks, and possibly a couple of images. If the amount of images is limited, you could add a picture related to Finland. — Preceding unsigned comment added by JNEURO (talk • contribs) 00:38, 7 April 2014 (UTC)

Hyperlinks were added wherever possible and when relevant. For some topics, Wikipedia lacked articles and thus we tried to explain the topics to the best of our abilities. No readily available images of the gene mutation were available for use on this page. Other pictures would not enhance the article.--Sydval612 (talk) 18:57, 24 April 2014 (UTC)

Secondary Review- For the amount of information that was available to you guys and the amount of research that is out there I believe that you guys did a good job on trying to include what you possibly could. When possible though I feel like adding more hyperlinks adds more to the article because readers can move between many different pages while reading your article if they are confused about anything. Some of the little facts you included did seem helpful though. Overall, good job I really liked the flow of it. 134.48.160.175 (talk) 15:21, 7 April 2014 (UTC)karora19

Hyperlinks were added wherever possible and when relevant. For some topics, Wikipedia lacked articles and thus we tried to explain the topics to the best of our abilities. --Sydval612 (talk) 18:57, 24 April 2014 (UTC)

'Primary Review': After seeing your note to the reviewers I think your group did a really good job of covering the topic at hand. You seemed to have covered Northern Epilepsy Syndrome with the limited materials at hand. Everything was well written and understandable to the normal viewer. As for broad in coverage... I think that you probably made it as broad as can be with the amount of research you had to write the page. I really think you should add an image or two to the page and I think the History section should be the first section. You should inform the reader with what the syndrome is and then go into explanation of early childhood, adolescents, and adults. I also chose to look at the second source in your reference section, "Northern Epilepsy". The your information matches what was said in the article as it should and it seemed to be a good source. Overall, good job writing an article about a topic that has so little information available. It does seem a bit short but if you have found all you could then there is nothing you can do to make it longer. --Jordannetts (talk) 03:57, 8 April 2014 (UTC)

Disease pages on Wikipedia are to follow a specific layout with history at the end, but we agree that moving the history section to the beginning of the article would provide better context for the reader, and thus, this change has been made. As many links as possible have been made with additional explanations to further but briefly explain topics of the disease. No readily available images of the gene mutation were available for use on this page. Other pictures would not enhance the article.--Sydval612 (talk) 18:57, 24 April 2014 (UTC)

Primary Review: Overall this topic was well covered seeing as you had such limited and old sources. I looked over the third source on your reference list, "Northern epilepsy, a new member of the NCL family." and even though the link only leads to an abstract you made good use of the information in the abstract. For image use, I'm not sure what kinds of images you could add to this but if you could find an image of the CLN8 protein that would show the readers the protein that is being affected. Johnsep12 (talk) 04:33, 8 April 2014 (UTC)

No readily available images of the gene mutation were available for use on this page. Other pictures would not enhance the article. For the article that was referenced, we were able to access the entire document on the Marquette Wireless network. We are sorry that you were unable to access it, but assuredly we used the paper sufficiently to add to the article. --Sydval612 (talk) 18:57, 24 April 2014 (UTC)

Primary Review: Given that this is a rare condition, I think you all provided a mostly sufficient amount of information. There are some grammar issues (i.e. lack of punctuation in some areas that create run-on sentences), but the writing itself is decent in this article. You all might consider making some grammar edits though. It appears that you all were able to find secondary sources; however, I'm not sure if you fully utilized these sources. I read through your second source, "Neuronal Ceroid Lipofuscinosis 8 via the CLN8 Gene," and I found some information that could be used to enhance your article. For example, to add length and detail to your article, you could explain the difference between 1-CLN8 diseases and 2-CLN8 diseases. Also, you could describe the testing procedures for diagnosis in detail since you don't have any links to other pages for further explanation in this section. Furthermore, I think you may be able to give a little more information on the affects of the medications prescribed to patients suffering from this condition. Although you link the pages for a couple of these drugs, it might be beneficial to give a short explanation for how these drugs work and how they help. Overall, if you could explain all of your points in just a little more detail so the reader doesn't have to search through links to get the gist of everything, that would be helpful. Maybe you could imagine that someone without an extensive background in biology is reading this, and correspondingly add information that would make it a bit easier for them to understand. This would improve your "broad coverage" rating. This article is definitely neutral, so good job on that! I realize finding pictures is difficult, especially when the condition is rare and Wikipedia Commons doesn't have something already available, but if you really want an image, maybe you could find a map of Finland or a picture of someone with NCL to supplement. All in all, I think you all did a nice job; this article just calls for a little more detail that I think you all should be able to find in the articles you have. --MUbrooke31

Grammatical errors have all been revised or reworded. We have clarified the difference between 1-CLN8 and 2-CLN8 disease but because ours is very distinct, we want to keep the main focus on the Northern Epilepsy. In regards diagnosis of the disease, it is based primarily on genetics and the analysis that goes along with it was expressed in the article to the best of our ability. Additionally, explanations for the treatment drugs have been offered. We added as much detail to the article as possible without overwhelming the reader and with the limited information that was available to us. No readily available images of the gene mutation were available for use on this page and we felt that other pictures would not enhance the article.--Sydval612 (talk) 18:57, 24 April 2014 (UTC)

Secondary review

The article seems to be of an appropriate length due to the lack of abundant sources and information. This is perfectly understandable because of the rarity of the disease and the isolation of the disease to Finland. The article is very well written and the information presented is understandable. It would be nice to see more pictures but, it is understandably difficult to find non-copywrited images. Other than that, it was a pleasant article to read. 7243HODGSOZ (talk) 20:55, 9 April 2014 (UTC)

Thanks for understanding our lack of pictures due to copyright issues. No other pictures were relevant to the article.--Sydval612 (talk) 18:57, 24 April 2014 (UTC)