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Bioinformatics (BFX) Workshop

Welcome to the Fall 2022 and Spring 2023 Bioinformatics (BFX) Workshop!

Objectives

This workshop series is designed for people who want to:

  1. learn the fundamentals of computational genomics
  2. use this information to improve and expedite their research
  3. expand their knowledge by hearing from experts in other subject areas

Schedule

Weekly Workshops on Mondays @ 10am in Mid-Campus Center (MCC) 11th floor Main Conference Room (Room #11504)

Please see the Communications section below for accessing the Office 365 group to find the Outlook Calendar invite. To be automatically notified of cancellations or changes to scheduling, ex. Room # changes, please accept the Outlook Calendar invite. One of the organizers listed in the Communications section can forward the Outlook Calendar invite upon request.

The BFX Workshop schedule, subject to change, is available below. Previous years' course materials can still be accessed in the "archive" folder. Additionally, a Zoom recording of each Workshop session will be made available shortly after each session. NOTE: See Participation for more details about external or remote participation.

The last Monday of each month will be a short lecture (15-30m), followed by open "office hours" to get help with assignments, or ask for advice about your own projects. Please contact the organizers if you have suggestions for additional lectures.

Date Topic(s) Presenter(s)
September 12, 2022 Workshop Intro and Prerequisite Review Chris Miller, Jason Walker
September 19, 2022 Sequence Data Generation and Manipulation Chris Miller
September 26, 2022 Command line tips, office hours Chris Miller
October 3, 2022 DNA Alignment Fundamentals Jason Walker
October 10, 2022 Office Hours
October 17, 2022 DNA Alignment in the Cloud Jason Walker
October 24, 2022 Germline Variant Calling Alex Paul, Chris Miller
October 31, 2022 Somatic Variant Calling Chris Miller
November 7, 2022 Exploring Data + Office Hours
November 14, 2022 Parsing and Filtering VCFs with Python John Garza, Susanna Kiwala
November 21, 2022 THANKSGIVING BREAK
November 28, 2022 R basics Chris Miller
December 5, 2022 Data visualization with R and ggplot2 Chris Miller
December 19, 2022 Data Munging/Cleaning in R Chris Miller
December 26, 2022 WINTER BREAK
January 2, 2023 WINTER BREAK
January 9, 2023 RNAseq part 1 Kelsy Cotto
January 16, 2023 MLK Day - no meeting
January 23, 2023 RNAseq part 2 Kelsy Cotto
January 30, 2023 Office Hours
February 6, 2023 ctDNA/Error-corrected sequencing Aadel Chaudhuri
February 13, 2023 Epigenomics, ChIP/ATAC/WGBS Chris Miller
February 20, 2023 President's Day - no meeting
February 27, 2023 Office Hours
March 6, 2023 Single-cell RNAseq Jennifer Foltz
March 13, 2023 Single-cell RNAseq Jennifer Foltz
March 20, 2023 Spring Break - no meeting
March 27, 2023 Long Read Sequencing/Office Hours Chris Miller
April 3, 2023 Microbial Genomics/16S seq Brigida Rusconi
April 10, 2023 Genome Assembly/Pangenome Juan Macias-Velasco
April 17, 2023 Cloud Computing - getting started Malachi Griffith
April 24, 2023 Office Hours

Participation

There are no requirements or qualifications to participate in the BFX Workshop. All we ask is that any willing participant visit our Prerequisite tutorial to understand the computer systems, tools, and languages that will be used throughout the course. Most of the languages and tools used are common to all fields and applications of Bioinformatics. No academic credits are earned for attending the course and there no attendance requirements. There will be "assignments" given during some lectures and we strongly encourage you to complete them in order to get the most out of the course - there is no substitute for hands-on learning!

For external or remote asyncronous participation, we suggest watching each weekly Zoom recording available shortly after each in-person session and strongly encourage interaction via Slack. The #bfx_workshop Slack channel is the primary form of interaction between workshop attendees, external participants, organizers, and presenters.

Organizers

This workshop is a collaborative effort between the Institute for Clinical and Translational Sciences (ICTS), McDonnell Genome Institute (MGI), Department of Medicine, Division of Hematology & Oncology, and Department of Pediatrics with faculty, staff, and student representation and participation from many other Institutes, Departments, and Divisions at Washington University School of Medicine in St. Louis.

The organizers would like to specifically thank the ICTS Precision Health function for supporting the Bioinformatics Workshop. NIH CTSA Grant Number UL1TR002345

The organizers and presenters of this workshop have multi-disciplinary backgrounds in Bioinformatics, Medicine, Computational Biology, Genetics, Computer Science, Oncology, Virology, Information Systems, Microbiology, Immunology, and many other combinations of both Data and Biological Sciences.

This team of organizers and presenters are committed to sharing best practice methods, technology, and knowledge from decades of experience working in these fields of study. New and novel applications of genome sequencing data are constantly evolving and even more so the analytical processes and tools used to translate data to information and knowledge are ever growing and changing. The team leading this workshop will focus on standard best practices while having an eye toward the future direction of each Bioinformatics topic.

Communications

Slack

For members of the ICTS Precision Health Slack organization ictsprecisionhealth.slack.com, please use the #bfx-workshop channel. If you do not have access to the ICTS Precision Health Slack organization please email one of the following:

j.mckenzie at wustl.edu

jason.walker at wustl.edu

c.a.miller at wustl.edu

Email

An Office 365 Group named Bioinformatics is used to distribute Calendar invites, announcements, and information regarding this workshop. Questions are welcome as well, but please be mindful that over 100 people subscribe to this alias. Click here to join.

The email address is:

bioinformatics at gowustl.onmicrosoft.com

Archived Lectures

If you'd like to look back at past sessions, course info and lectures from the 2020-2021 and 2021-2022 academic year are available in the archive.