[go: nahoru, domu]
Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

Sign up for GitHub

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Jump to bottom

Recent KP.3.1.1 + S:A397V 16 sequences , 6 countries #1695

Open
FedeGueli opened this issue Jul 4, 2024 · 7 comments
Open

Recent KP.3.1.1 + S:A397V 16 sequences , 6 countries #1695

FedeGueli opened this issue Jul 4, 2024 · 7 comments
Labels
DeFLuQE S:S31-+S:F456L+S:Q493E KP.3 Rapid review needed S:397

Comments

@FedeGueli
Copy link
FedeGueli commented Jul 4, 2024 •
edited
Loading

KP.3.1.1 is actually the lineage growing faster globally with a global share around 10% in the very few last weeks
(6% outside Spain)
Now there is a recent small branch that got S:A397V , it is predicted to increase binding, lowering entry and improving slighty escape on a XBB.1.5 backbone by Bloom and Dadonaite
Screenshot 2024-07-04 alle 19 37 52
It was quite uncommon in the pandemic being sampled less than 400 times ( 1/4 of them in AY.4)
hence i propose it here

Defining mutations:
KP.3.1.1 > A7330T, S:A397V (C22752T)
Query: A7330T,C22752T
Samples: 4
Countries : Spain (2), Canada, Netherlands
IDs:EPI_ISL_19201724, EPI_ISL_19229209, EPI_ISL_19230347,
EPI_ISL_19231071
Tree
Screenshot 2024-07-04 alle 19 32 10
https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_1c48e_6d8440.json?c=userOrOld&label=id:node_11513231
@aviczhl2 aviczhl2 added DeFLuQE S:S31-+S:F456L+S:Q493E and removed S:31 labels Jul 5, 2024
@Huachuan1120
Copy link

The fifth sequence, from Switzerland, collected on June 18, EPI_ISL_19240398.

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 4 sequences , 3 countries Recent KP.3.1.1 + S:A397V 5 sequences , 4 countries Jul 6, 2024
@FedeGueli
Copy link
Author

thank you

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 5 sequences , 4 countries Recent KP.3.1.1 + S:A397V 6 sequences , 5 countries Jul 8, 2024
@FedeGueli
Copy link
Author
  • 1 Netherlands

@Huachuan1120
Copy link
  • 1 Netherlands

EPI_ISL_19254475, collected in Ireland on June 23, is the 7th sequence and the true fifth country.
IMG_0161

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 6 sequences , 5 countries Recent KP.3.1.1 + S:A397V 7 sequences , 5 countries Jul 9, 2024
@FedeGueli
Copy link
Author
  • 1 Netherlands

EPI_ISL_19254475, collected in Ireland on June 23, is the 7th sequence and the true fifth country. IMG_0161

thx i wrongoed the count.

@Huachuan1120
Copy link

EPI_ISL_19258758, collected in England, UK on June 24. This is the eighth related sequence and the sixth country to report it.
IMG_0189

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 7 sequences , 5 countries Recent KP.3.1.1 + S:A397V 8 sequences , 6 countries Jul 12, 2024
@Huachuan1120
Copy link

On July 15, 8 new related sequences were submitted, including: Spain +2, Canada +6, bringing the total number of related sequences to 16.

@FedeGueli FedeGueli changed the title Recent KP.3.1.1 + S:A397V 8 sequences , 6 countries Recent KP.3.1.1 + S:A397V 16 sequences , 6 countries Jul 16, 2024
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Assignees
No one assigned
Labels
DeFLuQE S:S31-+S:F456L+S:Q493E KP.3 Rapid review needed S:397
Projects
None yet
Milestone
No milestone
Development

No branches or pull requests
3 participants
@aviczhl2 @FedeGueli @Huachuan1120