Maurer et al., 2009 - Google Patents
New Approaches to the Synthesis of Addressable Microarray Molecular LibrariesMaurer et al., 2009
- Document ID
- 13852958025501155357
- Author
- Maurer K
- Moeller K
- Publication year
- Publication venue
- Microarrays: Preparation, Microfluidics, Detection Methods, and Biological Applications
External Links
Snippet
Approaches for the synthesis of molecular libraries on addressable arrays of microelectrodes are presented. In each case, substrates are fixed to a polymer coating of the array in the regions proximal to the microelectrodes. Selected micro-electrodes are then …
- 238000003786 synthesis reaction 0 title abstract description 38
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL CHEMISTRY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
- C40B30/00—Methods of screening libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Venkatasubbarao | Microarrays–status and prospects | |
LeProust et al. | Digital light-directed synthesis. A microarray platform that permits rapid reaction optimization on a combinatorial basis | |
Tesfu et al. | Building addressable libraries: the use of electrochemistry for generating reactive Pd (II) reagents at preselected sites on a chip | |
JP2009509175A (en) | Method and CMOS-type device for analyzing molecules and nanomaterials by electrically reading selective binding events on functional electrodes | |
US20060151335A1 (en) | Process for performing an isolated Pd(0) catalyzed reaction electrochemically on an electrode array device | |
Kodadek et al. | Techniques: Oxidative cross-linking as an emergent tool for the analysis of receptor-mediated signalling events | |
CA2935138C (en) | Marker for generating binding information on biomolecules and nucleic acids, preparation method therefor, and method and apparatus for analyzing biomolecule by using same | |
Meini et al. | A sensitive and selective thrombin impedimetric aptasensor based on tailored aptamers obtained by solid-phase synthesis | |
Tesfu et al. | Building Addressable Libraries: Site Selective Coumarin Synthesis and the “Real-Time” Signaling of Antibody− Coumarin Binding | |
Yudin et al. | Combinatorial electrochemistry | |
Graaf et al. | Chemoselectivity and the Chan–Lam coupling reaction: adding amino acids to polymer-coated microelectrode arrays | |
Tian et al. | Building addressable libraries: The use of electrochemistry for spatially isolating a Heck reaction on a chip | |
Hu et al. | Building addressable libraries: Site-selective Suzuki reactions on microelectrode arrays | |
Nguyen et al. | Microelectrode arrays: A general strategy for using oxidation reactions to site selectively modify electrode surfaces | |
Huang et al. | Iridium (III) solvent complex-based electrogenerated chemiluminescence and photoluminescence sensor array for the discrimination of bases in oligonucleotides | |
US7507837B2 (en) | Process for performing an isolated Pd(II)-mediated oxidation reaction | |
Maurer et al. | New Approaches to the Synthesis of Addressable Microarray Molecular Libraries | |
JP2010524459A (en) | Nucleic acid chip for generating binding profile of unknown biomolecule and single-stranded nucleic acid, method for producing nucleic acid chip, and method for analyzing unknown biomolecule using nucleic acid chip | |
Tanabe et al. | Building addressable libraries: Amino acid derived fluorescent linkers | |
Souteyrand et al. | Use of microtechnology for DNA chips implementation | |
Kesselring et al. | Building addressable libraries: Site-selective formation of an N-acyliminium ion intermediate | |
Moeller | Electrochemically generated organometallic reagents and site-selective synthesis on a microelectrode array | |
EP4107271A1 (en) | Devices, methods and compositions for aptamer screening | |
JP4324707B2 (en) | DNA chip and biosensor using the same | |
US20050048551A1 (en) | Analyte evaluating device, method for evaluating analyte and method for manufacturing analyte evaluating device |