CN107088079A - Biodegradable vascular anastomosis ring/wheel and its Special surgical instrument - Google Patents
Biodegradable vascular anastomosis ring/wheel and its Special surgical instrument Download PDFInfo
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- CN107088079A CN107088079A CN201710388602.2A CN201710388602A CN107088079A CN 107088079 A CN107088079 A CN 107088079A CN 201710388602 A CN201710388602 A CN 201710388602A CN 107088079 A CN107088079 A CN 107088079A
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- anastomosis ring
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- 230000002792 vascular Effects 0.000 title claims abstract description 130
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- 238000006731 degradation reaction Methods 0.000 abstract description 21
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- 239000002473 artificial blood Substances 0.000 abstract description 6
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- 238000007363 ring formation reaction Methods 0.000 description 8
- 238000004458 analytical method Methods 0.000 description 7
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- 229920000747 poly(lactic acid) Polymers 0.000 description 7
- 239000004626 polylactic acid Substances 0.000 description 7
- 239000011701 zinc Substances 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 6
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 6
- 229910052725 zinc Inorganic materials 0.000 description 6
- 229910000861 Mg alloy Inorganic materials 0.000 description 5
- 238000002441 X-ray diffraction Methods 0.000 description 5
- PGTXKIZLOWULDJ-UHFFFAOYSA-N [Mg].[Zn] Chemical compound [Mg].[Zn] PGTXKIZLOWULDJ-UHFFFAOYSA-N 0.000 description 5
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- 238000011587 new zealand white rabbit Methods 0.000 description 2
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B17/115—Staplers for performing anastomosis in a single operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1103—Approximator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1107—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis for blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
- A61B2017/1132—End-to-end connections
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
The invention discloses a kind of biodegradable vascular anastomosis device, Special surgical instrument and its application method, it is used between human vas, coincideing between artificial blood vessel or between human vas and artificial blood vessel, the the first anastomosis ring/wheel and the second anastomosis ring/wheel that the vascular anastomosis device cooperates coaxial by a pair are constituted, and anastomosis ring/wheel includes vessel support support, clamp bracket and the circumferentially distributed identical pin of vessel support support free-end.The matching surface of vascular anastomosis device of the present invention is coaxial geometry, is coincide efficient, and the area that coincide is big, improves success rate of operation and reduces previous anastomotic and collapses out phenomenon.The present invention is prepared using Biodegradable material, pass through rational structure design, so that the vascular anastomosis ring/wheel can be after surgery human body degraded, and relatively complete structure is kept in degradation process, both according to the condition of different blood vessel corresponding effectively supporting time can be maintained to keep vascular anastomosis ring/wheel function after surgery, foreign matter residual risk caused by the identical method of tradition machinery can be avoided again.Special equipment provided by the present invention integrates clamping and identical function, simplifies surgical procedure, improves procedure efficiency.
Description
Technical field
The present invention relates to a kind of medical surgery operating theater instruments implant and its Special surgical instrument, espespecially a kind of vascular anastomosis
Device, Special surgical instrument and its application method.
Background technology
Vascular anastomosis technology is considered as the foundation stone of microsurgery, and its discipline range being related to is wide, and identical relationship between quality is arrived
The success or failure of operation.Vascular anastomosis method can be divided into needlework sewing and the major class of Sutureless jacquard CAD two, traditional small vessel anastomosis
Method is end-to-end interrupted suture, but this method has many weak points：It is cumbersome, take long, thin vessels
ISR problem after coincideing etc..Sutureless jacquard CAD can be summed up：Embedding inosculating method, heat setting jacquard CAD, bonding jacquard CAD and
Mechanical anastomosis method.Blood vessel, which is inserted in jacquard CAD, to be included being inserted in sutured anastomosis method and is inserted in bonding jacquard CAD, compared with sutured anastomosis method
Compared with embedding inosculating method blood vessel internal membrane damage is light, and sewing needle number is few, and the time that coincide is short.But there is also the defect that can not be ignored：Closely
End blood vessel must be inserted into distal vessels, and this operation is relatively complicated；Blood vessel needs enough length, when coincideing tensioned not
Preferably use；External diameter<1mm blood vessel is not suitable for using the jacquard CAD.Laser heat setting jacquard CAD is made using the laser thermal effect of low-power
The elastomer and collagenous fibres of externa and middle film are changed into gel state from collosol state and make blood vessel " welding ".Bonding kiss
Legal is that the blood vessel two ends of close apposition are glued together using adhesive of medical to make vascular anastomosis.No matter which kind of bonding is used
Agent, it is necessary to smeared again after blood vessel close apposition and avoid adhesive intravasation chamber.In addition, previous anastomotic elasticity after bonding
Difference, matter are crisp, and adhesive has certain toxicity, blood vessel two ends need to be maintained into open state during bonding, prevent from collapsing, it is therefore desirable to first
Blood vessel or built-in hollow stent are drawn in suture needle.
Blood vessel machinery jacquard CAD is the vascular anastomosis method that suture is substituted or partly replaced with special vascular anastomosis device,
Also referred to as blood vessel anastomat method, is the identical method of Sutureless of domestic and international most study.Modern mechanical vascular anastomosis method is by kiss
Tiretube process, magnetic tube method, anastomosis clamp method and needle ring method can be divided into by closing principle.The application of mechanical vascular anastomosis significantly simplify
Operation technique, shortens operating time, reduces tissue damage bleeding and postoperative infection chance in art, makes some in usual conditions
Under it is impracticable operation carried out.Blood vessel anastomat as described in CN85106639B, it is docked by Special surgical instrument
It coincide, simple to operate, it is firm to coincide.But the greatest problem that they are present is exactly that anastomosis ring/wheel or draw point be not biodegradable, kiss
Previous anastomotic and surrounding are for good and all stayed in after the completion of conjunction, caused inflammatory reaction is even heavier than conventional suture method.
In view of at present there are different defects, a kind of simple, quick and safe blood vessel kiss in existing vascular anastomosis method
Conjunction method is particularly important.
The content of the invention
It is an object of the invention to overcome traditional suture the to coincide shortcoming of operating time length that method is present and existing
Anastomosis ring/the pin that coincide of what mechanical vascular anastomosis device was present leave nonabsorable causes the shortcoming of inflammatory reaction, and there is provided one kind
Vascular anastomosis can fast and safely be carried out and biodegradable vascular anastomosis device.
To realize object above, the present invention provides a kind of vascular anastomosis device, includes the vascular anastomosis of a pair of mutual cooperations
Ring/wheel, described vascular anastomosis ring/wheel is by a pair of mutual cooperations coaxial the first anastomosis ring/wheel and the second anastomosis ring/wheel structure
Into anastomosis ring/wheel includes vessel support support and clamp bracket；The one end open of described vessel support support and described folder
Hold support to be connected, another end opening of described vessel support support is circumferentially distributed identical pin；The first wherein described kiss
The outer surface of the vessel support support of cyclization/wheel can be nested in the interior table of the vessel support support of described the second anastomosis ring/wheel
Face；Described identical pin is located at homonymy after the first anastomosis ring/wheel is nested with the second anastomosis ring/wheel, and described clamp bracket exists
It is located at offside after first anastomosis ring/wheel is nested with the second anastomosis ring/wheel.
The first described anastomosis ring/wheel and the second anastomosis ring/wheel vessel support support are truncated cone-shaped, and described first is identical
The clamp bracket of ring/wheel and the second anastomosis ring/wheel is cylinder, described truncated cone-shaped vessel support support smaller diameter end connection institute
The cylindrical clamp bracket stated, 3 identical pins are at least distributed with the truncated cone-shaped vessel support support larger diameter end.
The bus of the truncated cone-shaped vessel support support of first anastomosis ring/wheel and the mother of described cylindrical clamp bracket
Wire clamp angle is 15 °~75 °, the bus of the truncated cone-shaped blood vessel clamp bracket of second anastomosis ring/wheel and described cylinder clevis
The bus angle for holding support is 105 °~165 °, the truncated cone-shaped intravascular stent bus of described the first anastomosis ring/wheel with it is described
The angle of cylindrical clamp bracket bus formation and the bus of the truncated cone-shaped intravascular stent of the second described anastomosis ring/wheel with it is described
Cylindrical clamp bracket bus formation angle it is complementary.
The first described anastomosis ring/wheel is identical with the cylindrical stent internal diameter that the second anastomosis ring/wheel is used to clamp, internal diameter model
Enclose 1mm~20mm；The length of the truncated cone-shaped vessel support support bus of the first described anastomosis ring/wheel and the second anastomosis ring/wheel
It is 0.1~1 with the ratio between cylindrical clamp bracket internal diameter；The first described anastomosis ring/wheel is justified with the second anastomosis ring/wheel thickness with it
The length ratio of platform shape vessel support support bus is 0.2~0.5；On the first described anastomosis ring/wheel and the second anastomosis ring/wheel
The length of pin of coincideing and the length of described truncated cone-shaped vessel support support bus are 0.5~1；The first described anastomosis ring/wheel
The length ratio of cylindrical clamp bracket bus and truncated cone-shaped vessel support support bus be 1~2；The second described anastomosis ring/
The cylindrical clamp bracket bus of wheel is 0.5~1 with the length ratio of truncated cone-shaped vessel support support bus.
The identical pin distribution end of the second described anastomosis ring/wheel also includes at least two reinforced engagement means, in vascular anastomosis
When ring/wheel coincide, bent with identical pin.
Described anastomosis ring/wheel is made up of Biodegradable medical material.
It is preferred that, biodegradable medical material includes purity>99.99% metallic zinc or purity>99.99% gold
It is 1%~99% zinc magnesium alloy to belong to magnesium or Zn content.
It is preferred that, other Biodegradable medical materials include but is not limited to PLLA PLLA, polylactic acid PLA.
The present invention also provides a kind of anastomosis clamp for coordinating vascular anastomosis device as claimed in claim 1 to use, described kiss
Co-clip includes the first anastomosis clamp and the second anastomosis clamp, and the first described anastomosis clamp and the second anastomosis clamp include gripping section, hinge
Section and handling section, are connected between the first described anastomosis clamp and the second anastomosis clamp by dismountable mode；Described gripping section
Section and claim 1 described in anastomosis ring/wheel in clamp bracket section to cooperation；Second anastomosis clamp is provided with
Baltimore groove, during for vascular anastomosis, by identical pin flexural deformation, realizes that blood vessel firmly coincide.
Described anastomosis clamp gripping section has a pair of clamp assemblies, and described clamp assemblies are by male clip assembly and female clip assembly structure
Into male clip assembly is connected through the hinge with female clip assembly, and torsion circle has been coupled on hinge axis, is realized and is coincide by the elastic force of torsion spring
Locking between the clamp bracket of folder and vascular anastomosis device as claimed in claim 1；Described public clip assembly can be integral
Form on anastomosis clamp, can also be connected through the hinge on anastomosis clamp.
Dismountable connected mode can be hinge connection, and the first anastomosis clamp hinge is fixed in the shaft end of the hinge
Section, is provided with corresponding pan, the first anastomosis clamp can be real in certain angle with the second anastomosis clamp in the second anastomosis clamp hinge section
The installation and dismounting of existing hinge, angle are desirable 10 °~170 °.
Described clamping g. slice header is provided with location structure, the structure that described location structure matches for key and keyway.For
The accurate connection of male clip assembly and female clip assembly, while ensureing that the stress of male clip assembly and female clip assembly during vascular anastomosis is equal
It is even.
Described anastomosis clamp handling section is provided with circular arc graduated scale, described circular arc graduated scale insert the first anastomosis clamp with
The corresponding hole of second anastomosis clamp handheld terminal, its scale is between the first anastomosis clamp and the second anastomosis clamp clamping anastomosis ring/wheel
Air line distance conversion, be conducive to quickly measuring the length of vessel that need to be supplemented.
It is preferred that, described circular arc graduated scale and first coincide, the first anastomosis clamp individual member each other.
Optionally, described circular arc graduated scale and the first anastomosis clamp are integrally formed.
Optionally, described circular arc graduated scale and the second anastomosis clamp are integrally formed.
During operation, first according to external caliber select a pair of internal diameters same or anastomosis ring no more than 0.3~0.5mm/
Wheel；Corresponding special equipment is selected, the first anastomosis ring/wheel, the second anastomosis ring/wheel are clamped in the first anastomosis clamp and by it respectively
Between the through hole of two anastomosis clamps；The disconnected section of blood vessel is passed through to turn down after the cylindrical stent of anastomosis ring/wheel and hung on identical pin；By
One anastomosis clamp is connected through the hinge with the second anastomosis clamp, optionally inserts circular arc graduated scale；It is real by pressing handling section
Show drawing close for vascular anastomosis ring/wheel；Vascular anastomosis its further complete from centering under the cooperation of round table surface again；Continue to press hand-held
Section, the identical pin of vascular anastomosis ring/wheel is deformed along annular curved, realizes coincideing for ends of vessels.
The present invention has the advantages that：
1. the present invention is for coincideing between human vas, between artificial blood vessel or between human vas and artificial blood vessel,
Matching surface is coaxial geometry, identical efficient, and the area that coincide is big, improves success rate of operation and reduces previous anastomotic and collapses out now
As.
2. the pin that coincide is in bend by pressure into nearly semicircle, obvolvent is therefore fixed in the inner side of anastomosis ring/wheel conical surface, resists
Tensile strength is high, is difficult to release.
3. vascular anastomosis ring/take turns its pin distribution end that coincide and circumferentially may be added to that and lack 2 reinforced engagement means, in vascular anastomosis
When ring/wheel coincide, bent with identical pin, therefore coincideing available for larger blood vessel.
4. prepared by present invention application absorbable material so that 1-2 can be human body drop to the vascular anastomosis ring/wheel after surgery
Solution, it is to avoid foreign matter residual risk caused by the identical method of tradition machinery.
5. vascular anastomosis ring/wheel in the present invention passes through rational structure design so that vascular anastomosis ring/wheel can be in art
Blood vessel is kept to maintain corresponding effectively supporting time to keep vascular anastomosis ring/wheel function according to the condition of different blood vessel afterwards.
6. the clamping of professional apparatus collection and coincide function and one used in the present invention, simplify surgical procedure, improve hand
Art efficiency.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
There is the accompanying drawing used required in technology description to be briefly described, it should be apparent that, drawings in the following description are only this
Some embodiments described in inventive embodiments, for those of ordinary skill in the art, can also be obtained according to these accompanying drawings
Obtain other accompanying drawings.
Fig. 1 is one embodiment of the present invention vascular anastomosis ring/wheel construction schematic diagram；
Fig. 2 is one embodiment of the present invention vascular anastomosis ring/wheel profile.
Fig. 3 is the second anastomosis ring of one embodiment of the present invention/wheel construction schematic diagram.
Fig. 4 is the structural representation of one embodiment of the present invention Special surgical instrument anastomosis clamp；
Fig. 5 is the top view of one embodiment of the present invention Special surgical instrument anastomosis clamp；
Fig. 6 is the ring channel structures partial enlarged drawing of the Special surgical instrument anastomosis clamp based on Fig. 5 present invention.
Fig. 7 is the hinge arrangement partial enlarged drawing of the Special surgical instrument anastomosis clamp based on Fig. 5 present invention.
Fig. 8 is the circular arc graduated scale partial enlarged drawing of the Special surgical instrument anastomosis clamp based on Fig. 5 present invention.
Fig. 9 is the left view of one embodiment of the present invention Special surgical instrument anastomosis clamp.
Figure 10 is the location structure partial enlarged drawing based on Fig. 9 present invention and Special surgical instrument anastomosis clamp
Figure 11 is the preferred embodiment gripping section structural representation of Special surgical instrument anastomosis clamp one of the present invention.
The reference and part being related in accompanying drawing are as follows：
The first anastomosis rings of 1-/wheel 11- truncated cone-shaped support 12- cylindrical stents 13- coincide pin
The identical pin 24- reinforced engagement means of the second anastomosis rings of 2-/wheel 21- truncated cone-shaped support 22- cylindrical stents 23-
The female clip assembly 32- hinge section 33- handling sections of the male clip assembly 312- of 3- the first anastomosis clamp 31- gripping sections 311-
The female clip assembly 42- hinge section 43- handling sections of the male clip assembly 412- of 4- the second anastomosis clamp 41- gripping sections 411-
5- circular arc graduated scales
6- torsion springs
Embodiment
The present invention is described in further detail with reference to the accompanying drawings and examples, but the implementation of the present invention is not limited only to
This.
The present invention devises a kind of vascular anastomosis device, includes vascular anastomosis ring/wheel of a pair of mutual cooperations, described blood
The the first anastomosis ring/wheel and the second anastomosis ring/wheel that pipe anastomosis ring/wheel cooperates coaxial by a pair are constituted, and anastomosis ring/wheel is included
Vessel support support and clamp bracket；The one end open of described vessel support support is connected with described clamp bracket, institute
Another end opening for the vessel support support stated is circumferentially distributed identical pin；The blood vessel branch of the first wherein described anastomosis ring/wheel
The outer surface of support support can be nested in the inner surface of the vessel support support of described the second anastomosis ring/wheel；Described identical pin
Be located at homonymy after the first anastomosis ring/wheel is nested with the second anastomosis ring/wheel, described clamp bracket the first anastomosis ring/wheel with
It is located at offside after second anastomosis ring/wheel is nested.
The first described anastomosis ring/wheel and the second anastomosis ring/wheel vessel support support are truncated cone-shaped, and described first is identical
The clamp bracket of ring/wheel and the second anastomosis ring/wheel is cylinder, described truncated cone-shaped vessel support support smaller diameter end connection institute
The cylindrical clamp bracket stated, 3 identical pins are at least distributed with the truncated cone-shaped vessel support support larger diameter end.
As shown in figure 1, described vascular anastomosis ring/wheel is coincide by the first anastomosis ring/wheel 1 of a pair of mutual cooperations with second
Ring/wheel 2 is constituted, and described the first anastomosis ring/wheel includes truncated cone-shaped support 11, cylindrical stent 12 and identical pin for clamping
13, described the second anastomosis ring/wheel includes truncated cone-shaped support 21, cylindrical stent 22 and identical pin 23 for clamping.
As shown in Fig. 2 the described smaller diameter end of truncated cone-shaped support 11 connects described cylindrical stent 12, its angle α is
15 °~75 °；The described cylindrical stent 22 of the described smaller diameter end of truncated cone-shaped support 21 connection, its angle β is 105 °~
165 °, described angle α, β supplementary angle each other.Both can be between A ' B ' in AB and truncated cone-shaped support 21 in the truncated cone-shaped support 11
It is straight line connection or arc connection, the length of the truncated cone-shaped support bus refers to AB and circle in truncated cone-shaped support 11
In platform shape support 21 between A ' B ' straight line length.
Its larger diameter end of truncated cone-shaped support 11 of the first described anastomosis ring/wheel 1 it is circumferentially distributed 3 identical pins 13.
Its larger diameter end of truncated cone-shaped support 21 of the second described anastomosis ring/wheel 2 it is circumferentially distributed 3 identical pins 23.
Described identical pin 13, the pin 23 that coincide are used to fix ends of vessels, and ends of vessels is fixed on after identical pin, described
First anastomosis ring/wheel 1 and the second anastomosis ring/wheel 2 are close to each other under described special equipment clamping and coordinate, coincide pin 13 with
Coincide the lateral bend into truncated cone-shaped support of pin 23, realizes that vascular anastomosis ring/wheel nesting of described mutual cooperation is fixed, and coincide
Ends of vessels.
As shown in figure 3, described its larger diameter end of truncated cone-shaped support 21 of second vascular anastomosis ring/wheel 2 circumferentially may be added to that
Few 2 reinforced engagement means 24, when vascular anastomosis ring/wheel coincide, bend with identical pin 23.
Described biodegradable vascular anastomosis ring/wheel is by purity>99.99% metallic zinc or purity>99.99%
Magnesium metal or according to it is different requirement mass ratioes containing zinc be 1%~99% zinc magnesium alloys or other Biodegradable medical materials
(such as PLLA PLLA, polylactic acid PLA) is made.
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and second of the first described anastomosis ring/wheel 1
The internal diameter of cylindrical stent 22 of anastomosis ring/wheel 2 is identical, inside diameter ranges 1mm-20mm,
The length and circle of the truncated cone-shaped vessel support support bus of the first described anastomosis ring/wheel and the second anastomosis ring/wheel
The ratio between cylindricality clamping shelf inner diameter is 0.1~1.
The length of the first described anastomosis ring/wheel and the second anastomosis ring/wheel thickness and its truncated cone-shaped vessel support support bus
The ratio between degree is 0.2~0.5；The length of identical pin and described round platform on the first described anastomosis ring/wheel and the second anastomosis ring/wheel
The length ratio of shape vessel support support bus is 0.5~1；The cylindrical clamp bracket bus of the first described anastomosis ring/wheel
Length ratio with truncated cone-shaped vessel support support bus is 1~2；The cylindrical clamp bracket of the second described anastomosis ring/wheel
The length ratio of bus and truncated cone-shaped vessel support support bus is 0.5~1.
As shown in figure 4, anastomosis clamp 3 of the described special equipment comprising a pair of mutual cooperations is carved with anastomosis clamp 4 and circular arc
Chi 5 is spent, wherein the first anastomosis clamp 3 is used to clamp the second anastomosis ring/wheel, the second anastomosis clamp 4 is used to clamp the first anastomosis ring/wheel.
The first described anastomosis clamp 3 includes gripping section 31, hinge section 32 and handling section 33.
The second described anastomosis clamp 4 includes gripping section 41, hinge section 42 and handling section 43.
Pass through dismountable hinge connection, the hinge between the first anastomosis clamp 3 and the second anastomosis clamp 4 as described in Figure 7
Shaft end fix and the hinge section 32 of the first anastomosis clamp；Corresponding pan is provided with the hinge section 42 of the second anastomosis clamp；First
The anastomosis clamp 4 of anastomosis clamp 3 and second can realize the installation and dismounting of hinge at angle γ angles, and angle γ is desirable 10 °~170 °.
As shown in figure 8, described circular arc graduated scale 5 can be inserted into the handheld terminal 13 of the first anastomosis clamp 1 and the hand of the second anastomosis clamp 2
Hold in 23 corresponding holes of end, straight line of its scale between the first anastomosis clamp 1 and the second anastomosis clamp 2 clamping anastomosis ring/wheel
Distance transform, is conducive to quickly measuring the length of vessel that need to be supplemented.
It is preferred that, described circular arc graduated scale 5, the first anastomosis clamp 3 and the first anastomosis clamp 4 individual member each other.
Optionally, described circular arc graduated scale 5 and the first anastomosis clamp 3 are integrally formed.
Optionally, described circular arc graduated scale 5 and the second anastomosis clamp 4 are integrally formed.
As shown in figure 4, the first described anastomosis clamp gripping section 31 has a pair of clamp assemblies, described clamp assemblies are pressed from both sides by public affairs
Component 311 is constituted with female clip assembly 312, and male clip assembly 311 is connected through the hinge with female clip assembly 312, is coupled on hinge axis
Torsion spring 6, realizes the locking of anastomosis clamp 31 by the elastic force of torsion spring 6.
The second described anastomosis clamp gripping section 41 has a pair of clamp assemblies, described clamp assemblies by public clip assembly 411 with
Female clip assembly 412 is constituted, and male clip assembly 411 is connected through the hinge with female clip assembly 412, and torsion spring 6 has been coupled on hinge axis, according to
The locking of anastomosis clamp 41 is realized by the elastic force of torsion spring 6.
Optionally, described public clip assembly 311 can be formed separately in the first anastomosis clamp 3 and the second kiss with public clip assembly 411
In co-clip 4.
It is preferred that, the public clip assembly 311 on the first anastomosis clamp is independently of the first anastomosis clamp 3, and public clip assembly 311 passes through hinge
It is connected on the first anastomosis clamp 3, the public clip assembly 411 on the second anastomosis clamp is formed on the second anastomosis clamp, realizes that gripping section exists
Pressure distribution is uniform during vascular anastomosis.
It is preferred that, the public folder that the public clip assembly 311 on the first anastomosis clamp is formed on the first anastomosis clamp 3, the second anastomosis clamp
The independence of component 411 and the second anastomosis clamp 4, public clip assembly 411 are connected through the hinge on the second anastomosis clamp 4, realize that gripping section exists
Pressure distribution is uniform during vascular anastomosis.
As shown in fig. 6, described gripping section 31 is provided with annular through-hole with the head of gripping section 41, its section is kissed with second respectively
Cyclization/wheel 2, the first anastomosis ring/section of wheel 1 are used to securely fix on anastomosis ring/wheel to cooperation, appropriate bore, and second
Through hole periphery on anastomosis clamp is provided with annular groove, and its section is made up of the arc section of indent, during for vascular anastomosis, by identical pin
13 with the identical flexural deformation of pin 23, realize that blood vessel firmly coincide.
As shown in Figure 10, described gripping section 31 is provided with location structure with the head of gripping section 41, for realizing public clip assembly
311st, the accurate connection of male clip assembly 411 and female clip assembly 312, female clip assembly 412, while public folder during ensureing vascular anastomosis
The uniform force of component and female clip assembly.
By the first anastomosis ring/wheel, the second anastomosis ring/wheel be clamped in respectively the first anastomosis clamp and the second anastomosis clamp through hole it
Between；The disconnected section of blood vessel is passed through to turn down after the cylindrical stent of anastomosis ring/wheel and hung on identical pin；First anastomosis clamp and second are kissed
Co-clip is connected through the hinge, and optionally inserts circular arc graduated scale；Vascular anastomosis ring/wheel is realized by pressing handling section
Draw close；Vascular anastomosis its further complete coaxial under the cooperation of frustum cone side；Continue to press handling section, vascular anastomosis ring/wheel
Identical pin deformed along annular curved, realize ends of vessels coincide.
Embodiment 1
With normal rat (SD rats) for experimental subjects, experimental group carries out vascular anastomosis with stapling apparatus of the present invention, compares
Group is coincide with conventional suture.Cut off abdominal aorta row end to end anastomosis.Match result is estimated by every detection means, it is main
It is as follows：
1. previous anastomotic biomethanics is detected：Postoperative 8h, 24h, 14d and 30d, 1.0cm is about including cutting containing previous anastomotic
Vascular specimen, previous anastomotic burst pressure is determined with blast pressure detector for vascular anastomosis open, is determined with vascular anastomosis breaking tension
Instrument detection of broken tension force, is compareed between carrying out two groups, evaluates the security and feasibility of the identical method of Sutureless.
2. the unobstructed assessment of scenario of previous anastomotic：With color ultrasound, angiogram respectively at postoperative 8,24,72 hours and 1,2,3,4 weeks
And 3,6, assess within 12 months the unobstructed situations of previous anastomotic (blood flow rate, intraluminal diameter) of two groups of different identical methods, go forward side by side
Row compares.
3. stapling apparatus degraded is determined：Postoperative 1,3,6,12 months put to death animal, take out stapling apparatus：Scanning electron microscope sem
Analyze the form of stapling apparatus different time degradation point；X-ray diffraction (XRD) is divided the degradation product composition of zinc alloy surface
Analysis；Cleaned and weighed after stapler with butyric acid afterwards, calculate degradation rate, draw degradation curve, degradation rate rule is analyzed, with after an action of the bowels
It is continuous further to improve stapler.
Take as Figure 1 and Figure 4, a kind of biodegradable vascular anastomosis device, it is coaxial comprising a pair of mutual cooperations
Vascular anastomosis ring/wheel and its Special surgical instrument.
As shown in Fig. 2 the described smaller diameter end of truncated cone-shaped support 11 connects described cylindrical stent 12, its angle α is
75°；The described cylindrical stent 22 of the described smaller diameter end of truncated cone-shaped support 21 connection, its angle β is 105 °, described angle
α, β supplementary angle each other.
Its larger diameter end of truncated cone-shaped support 11 of the first described anastomosis ring/wheel 1 it is circumferentially distributed 3 identical pins 13.
Its larger diameter end of truncated cone-shaped support 21 of the second described anastomosis ring/wheel 2 it is circumferentially distributed 3 identical pins 23.
Described biodegradable vascular anastomosis ring/wheel mass ratio containing zinc is 20% zinc magnesium alloy.
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and second of the first described anastomosis ring/wheel 1
The internal diameter of cylindrical stent 22 of anastomosis ring/wheel 2 is identical, inside diameter ranges 1mm.
The ratio between the length of the truncated cone-shaped vessel support support bus of two described cyclizations/wheel and cylindrical stent internal diameter are
0.5。
Described vascular anastomosis ring/wheel it is characterized in that：The thickness of the first described anastomosis ring/wheel 1 and its truncated cone-shaped blood vessel branch
The length ratio for supportting the bus of support 11 is 0.2.
Described vascular anastomosis ring/wheel it is characterized in that：The thickness of the second described anastomosis ring/wheel 2 and its truncated cone-shaped blood vessel branch
The length ratio for supportting the bus of support 21 is 0.2.
On described vascular anastomosis ring/wheel coincide pin 13, coincide pin 23 length respectively with described truncated cone-shaped blood vessel branch
It is 0.5 to support the length of the bus of support 11, the length ratio of the bus of truncated cone-shaped vessel support support 21.
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and round platform of the first described anastomosis ring/wheel 1
The length ratio of the bus of shape vessel support support 11 is 1, cylindrical stent 22 and the truncated cone-shaped blood of described the second anastomosis ring/wheel 2
The length ratio of the bus of pipe supporting support 21 is 0.5.
As shown in figure 4, anastomosis clamp 3 of the described special equipment comprising a pair of mutual cooperations is carved with anastomosis clamp 4 and circular arc
Chi 5 is spent, wherein the first anastomosis clamp 3 is used to clamp the second anastomosis ring/wheel, the second anastomosis clamp 4 is used to clamp the first anastomosis ring/wheel.
The first described anastomosis clamp 3 includes gripping section 31, hinge section 32 and handling section 33.
The second described anastomosis clamp 4 includes gripping section 41, hinge section 42 and handling section 43.
Pass through dismountable hinge connection, the hinge between the first anastomosis clamp 3 and the second anastomosis clamp 4 as described in Figure 7
Shaft end fix and the hinge section 32 of the first anastomosis clamp；Corresponding pan is provided with the hinge section 42 of the second anastomosis clamp；First
The anastomosis clamp 4 of anastomosis clamp 3 and second can realize the installation and dismounting of hinge at angle γ angles, and angle γ is desirable 10 °~170 °.
As shown in figure 8, described circular arc graduated scale 5 can be inserted into the handheld terminal 13 of the first anastomosis clamp 1 and the hand of the second anastomosis clamp 2
Hold in 23 corresponding holes of end, straight line of its scale between the first anastomosis clamp 1 and the second anastomosis clamp 2 clamping anastomosis ring/wheel
Distance transform, is conducive to quickly measuring the length of vessel that need to be supplemented.
It is preferred that, described circular arc graduated scale 5, the first anastomosis clamp 3 and the first anastomosis clamp 4 individual member each other.
Optionally, described circular arc graduated scale 5 and the first anastomosis clamp 3 are integrally formed.
Optionally, described circular arc graduated scale 5 and the second anastomosis clamp 4 are integrally formed.
As shown in figure 5, the first described anastomosis clamp gripping section 31 has a pair of clamp assemblies, described clamp assemblies are pressed from both sides by public affairs
Component 311 is constituted with female clip assembly 312, and male clip assembly 311 is connected through the hinge with female clip assembly 312, is coupled on hinge axis
Torsion spring 6, realizes the locking of anastomosis clamp 31 by the elastic force of torsion spring 6.
The second described anastomosis clamp gripping section 41 has a pair of clamp assemblies, described clamp assemblies by public clip assembly 411 with
Female clip assembly 412 is constituted, and male clip assembly 411 is connected through the hinge with female clip assembly 412, and torsion spring 6 has been coupled on hinge axis, according to
The locking of anastomosis clamp 41 is realized by the elastic force of torsion spring 6.
Optionally, described public clip assembly 311 can be formed separately in the first anastomosis clamp 3 and the second kiss with public clip assembly 411
In co-clip 4.
It is preferred that, the public clip assembly 311 on the first anastomosis clamp is independently of the first anastomosis clamp 3, and public clip assembly 311 passes through hinge
It is connected on the first anastomosis clamp 3, the public clip assembly 411 on the second anastomosis clamp is formed on the second anastomosis clamp, realizes that gripping section exists
Pressure distribution is uniform during vascular anastomosis.
It is preferred that, the public folder that the public clip assembly 311 on the first anastomosis clamp is formed on the first anastomosis clamp 3, the second anastomosis clamp
The independence of component 411 and the second anastomosis clamp 4, public clip assembly 411 are connected through the hinge on the second anastomosis clamp 4, realize that gripping section exists
Pressure distribution is uniform during vascular anastomosis.
As shown in fig. 6, described gripping section 31 is provided with annular through-hole with the head of gripping section 41, its section is kissed with second respectively
Cyclization/wheel 2, the first anastomosis ring/section of wheel 1 are used to securely fix on anastomosis ring/wheel to cooperation, appropriate bore, and second
Through hole periphery on anastomosis clamp is provided with annular groove, and its section is made up of the arc section of indent, during for vascular anastomosis, by identical pin
13 with the identical flexural deformation of pin 23, realize that blood vessel firmly coincide.
As shown in Figure 10, described gripping section 31 is provided with location structure with the head of gripping section 41, for realizing public clip assembly
311st, the accurate connection of male clip assembly 411 and female clip assembly 312, female clip assembly 412, while public folder during ensureing vascular anastomosis
The uniform force of component and female clip assembly.
By the first anastomosis ring/wheel, the second anastomosis ring/wheel be clamped in respectively the first anastomosis clamp and the second anastomosis clamp through hole it
Between；The disconnected section of blood vessel is passed through to turn down after the cylindrical stent of anastomosis ring/wheel and hung on identical pin；First anastomosis clamp and second are kissed
Co-clip is connected through the hinge, and optionally inserts circular arc graduated scale；Vascular anastomosis ring/wheel is realized by pressing handling section
Draw close；Vascular anastomosis its further complete coaxial under the cooperation of frustum cone side again；Continue to press handling section, vascular anastomosis ring/wheel
Identical pin deformed along annular curved, realize ends of vessels coincide.
Should be biodegradable in vivo according to the vascular anastomosis device of the present invention.Due to being opened from implementation anastomosis of blood vessel
Begin to the gap between vascular inner surface to be filled only to need 2-3 weeks, so biodegradable vascular anastomosis ring/wheel is by can be biological
Degradable material is made, and the material is absorbed within the several months by live body.In this case, propped up by adjusting in vascular anastomosis ring/wheel
The proportion structure of support support 21, clamp bracket 22 and identical pin is kissed to keep the gap between vascular inner surface to be filled preceding blood vessel
The integrality of cyclization/wheel construction, to provide blood vessel enough mechanical supports.
Experiment effect shows：
1. previous anastomotic biomethanics is detected：Postoperative 8h, 24h, 14d and 30d, 1.5cm is about including cutting containing previous anastomotic
Vascular specimen, experimental group vascular anastomosis burst pressure and breaking tension are significantly higher than control group, the stapling apparatus anastomosis of blood vessel broken ends of fractured bone
Intensity higher than suture coincide method.
2. the unobstructed assessment of scenario of previous anastomotic：With color ultrasound, angiogram respectively at postoperative 8,24,72 hours and 1,2,3,4 weeks
And 3,6, assess within 12 months the unobstructed situations of previous anastomotic of two groups of different identical methods, it is found that suture coincide group in postoperative 4 weeks
Gradually occur tube chamber diameter stenosis, more normal hemadostewnosis more than 30%, and the identical group of stapling apparatus does not go out for postoperative 12 months yet
The narrow situation of existing vessel lumen.
3. stapling apparatus degraded is determined：Postoperative 1,3,6,12 months put to death animal, take kirsite stapling apparatus：ESEM
The form of sem analysis stapler different time degradation point；X-ray diffraction (XRD) is carried out to the degradation product composition of zinc alloy surface
Analysis；Cleaned and weighed after stapler with butyric acid afterwards, calculate degradation rate, draw degradation curve, analyze degradation rate rule, so as to
It is follow-up further to improve stapler.Absorbable stapling apparatus inserted rabbit artery after 3 months, and x-ray shows that the pin that coincide gradually is degraded,
Being coincide at 6 months, pin is completely invisible, and circular platform type support is remained in that completely, cylindrical stent partial disappearance, at 12 months, circle
Bench-type holder part disappears, and cylindrical stent is invisible.
Embodiment 2
Using new zealand white rabbit as experimental subjects, experimental group carries out vascular anastomosis, control group with the stapling apparatus of the present invention
It is coincide with conventional suture.Arteria carotis communis is cut off, row end-end coincide.Every detection means is same as Example 1 to match result.
Take as Figure 1 and Figure 4, a kind of biodegradable vascular anastomosis device, it is coaxial comprising a pair of mutual cooperations
Vascular anastomosis ring/wheel and its Special surgical instrument.
As shown in Fig. 2 the described smaller diameter end of truncated cone-shaped support 11 connects described cylindrical stent 12, its angle α is
45°；The described cylindrical stent 22 of the described smaller diameter end of truncated cone-shaped support 21 connection, its angle β is 135 °, described angle
α, β supplementary angle each other.
Its larger diameter end of truncated cone-shaped support 11 of the first described anastomosis ring/wheel 1 it is circumferentially distributed 5 identical pins 13.
Its larger diameter end of truncated cone-shaped support 21 of the second described anastomosis ring/wheel 2 it is circumferentially distributed 5 identical pins 23.
As shown in figure 3, described its larger diameter end of conical support 21 of second vascular anastomosis ring/wheel 2 can circumferentially add 2 plus
Strong ties device 24, when vascular anastomosis ring/wheel coincide, bends with identical pin 23.
Described biodegradable vascular anastomosis ring/wheel mass ratio containing zinc is 50% zinc magnesium alloy.
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and second of the first described anastomosis ring/wheel 1
The internal diameter of cylindrical stent 22 of anastomosis ring/wheel 2 is identical, inside diameter ranges 5mm.
The ratio between the length of the truncated cone-shaped vessel support support bus of two described cyclizations/wheel and cylindrical stent internal diameter are
0.3。
Described vascular anastomosis ring/wheel it is characterized in that：The thickness of the first described anastomosis ring/wheel 1 and its truncated cone-shaped blood vessel branch
The length ratio for supportting the bus of support 11 is 0.3.
Described vascular anastomosis ring/wheel it is characterized in that：The thickness of the second described anastomosis ring/wheel 2 and its truncated cone-shaped blood vessel branch
The length ratio for supportting the bus of support 21 is 0.4.
On described vascular anastomosis ring/wheel coincide pin 13, coincide pin 23 length respectively with described truncated cone-shaped blood vessel branch
It is 0.6 to support the length of the bus of support 11, the length ratio of the bus of truncated cone-shaped vessel support support 21.
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and round platform of the first described anastomosis ring/wheel 1
The length ratio of the bus of shape vessel support support 11 is 1.5, the cylindrical stent 22 and truncated cone-shaped of described the second anastomosis ring/wheel 2
The length ratio of the bus of vessel support support 21 is 0.7.
Choose the Special surgical instrument of corresponding size.
Experiment effect shows：
1. previous anastomotic biomethanics is detected：Postoperative 8h, 24h, 14d and 30d, 1.5cm is about including cutting containing previous anastomotic
Vascular specimen, experimental group vascular anastomosis burst pressure and breaking tension are significantly higher than control group, Anastomat hemorrhoidal circumcision ends of vessels
Intensity is higher than the identical method of suture, and Anastomat hemorrhoidal circumcision method validity is significantly higher than the identical method of suture.
2. the unobstructed assessment of scenario of previous anastomotic：With color ultrasound, angiogram respectively at postoperative 8,24,72 hours and 1,2,3,4 weeks
And 3,6, assess within 12 months the unobstructed situations of previous anastomotic of two groups of different identical methods, it is found that suture coincide group in postoperative 4 weeks
Gradually occur tube chamber diameter stenosis, more normal hemadostewnosis more than 20%, and Anastomat hemorrhoidal circumcision group does not occur for postoperative 12 months yet
The narrow situation of vessel lumen.
3. stapling apparatus degraded is determined：Postoperative 1,3,6,12 months put to death animal, take kirsite stapling apparatus：ESEM
The form of sem analysis stapling apparatus different time degradation point；X-ray diffraction (XRD) enters to the degradation product composition of zinc alloy surface
Row analysis；Cleaned and weighed after stapler with butyric acid afterwards, calculate degradation rate, draw degradation curve, analyze degradation rate rule, with
Continue after an action of the bowels and further improve stapling apparatus.Absorbable stapling apparatus inserted rabbit artery after 3 months, and x-ray, which is shown, coincide pin gradually
Degraded；Being coincide at 6 months, pin is completely invisible, and circular platform type support is remained in that completely, cylindrical stent partial disappearance；12 months
When, circular platform type support is invisible, and cylindrical stent is invisible.
Embodiment 3
Using small test with pig as experimental subjects, experimental group with the present invention stapling apparatus carry out vascular anastomosis, control group
It is coincide with conventional suture.Femoral artery is cut off, row end-end coincide.Every detection means is estimated and embodiment to match result
1 is identical.
Take as Figure 1 and Figure 4, a kind of biodegradable vascular anastomosis device, it is automatic right that it cooperates comprising a pair
In vascular anastomosis ring/wheel and its Special surgical instrument.
As shown in Fig. 2 the described smaller diameter end of truncated cone-shaped support 11 connects described cylindrical stent 12, its angle α is
75°；The described cylindrical stent 22 of the described smaller diameter end of truncated cone-shaped support 21 connection, its angle β is 105 °, described angle
α, β supplementary angle each other.
Its larger diameter end of truncated cone-shaped support 11 of the first described anastomosis ring/wheel 1 it is circumferentially distributed 5 identical pins 13.
Its larger diameter end of truncated cone-shaped support 21 of the second described anastomosis ring/wheel 2 it is circumferentially distributed 5 identical pins 23.
Described biodegradable vascular anastomosis ring/wheel mass ratio containing zinc is 60% zinc magnesium alloy.
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and second of the first described anastomosis ring/wheel 1
The internal diameter of cylindrical stent 22 of anastomosis ring/wheel 2 is identical, inside diameter ranges 20mm.
The ratio between length and cylindrical stent internal diameter of the truncated cone-shaped vessel support support bus of two described cyclizations/wheel are 1.
Described vascular anastomosis ring/wheel it is characterized in that：The thickness of the first described anastomosis ring/wheel 1 and its truncated cone-shaped blood vessel branch
The length ratio for supportting the bus of support 11 is 0.3.
Described vascular anastomosis ring/wheel it is characterized in that：The thickness of the second described anastomosis ring/wheel 2 and its truncated cone-shaped blood vessel branch
The length ratio for supportting the bus of support 21 is 0.3.
On described vascular anastomosis ring/wheel coincide pin 13, coincide pin 23 length respectively with described truncated cone-shaped blood vessel branch
It is 1 to support the length of the bus of support 11, the length ratio of the bus of truncated cone-shaped vessel support support 21.
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and round platform of the first described anastomosis ring/wheel 1
The length ratio of the bus of shape vessel support support 11 is 2, cylindrical stent 22 and the truncated cone-shaped blood of described the second anastomosis ring/wheel 2
The length ratio of the bus of pipe supporting support 21 is 1.
Choose the Special surgical instrument of corresponding size.
Experiment effect shows：
1. previous anastomotic biomethanics is detected：Postoperative 8h, 24h, 14d and 30d, 5cm blood is about including cutting containing previous anastomotic
Pipe sample, experimental group vascular anastomosis burst pressure and breaking tension are significantly higher than control group, Anastomat hemorrhoidal circumcision ends of vessels it is strong
Degree is higher than the identical method of suture, and Anastomat hemorrhoidal circumcision method validity is significantly higher than the identical method of suture.
2. the unobstructed assessment of scenario of previous anastomotic：With color ultrasound, angiogram respectively at postoperative 8,24,72 hours and 1,2,3,4 weeks
And 3,6, assess within 12 months the unobstructed situations of previous anastomotic of two groups of different identical methods, it is found that suture coincide group in postoperative 4 weeks
Gradually occur tube chamber diameter stenosis, more normal hemadostewnosis more than 20%, and Anastomat hemorrhoidal circumcision group does not occur for postoperative 12 months yet
The narrow situation of vessel lumen.
3. stapling apparatus degraded is determined：Postoperative 1,3,6,12 months put to death animal, take kirsite stapling apparatus：ESEM
The form of sem analysis stapling apparatus different time degradation point；X-ray diffraction (XRD) enters to the degradation product composition of zinc alloy surface
Row analysis；Cleaned and weighed after stapler with butyric acid afterwards, calculate degradation rate, draw degradation curve, analyze degradation rate rule, with
Continue after an action of the bowels and further improve stapling apparatus.Absorbable stapling apparatus inserted rabbit artery after 3 months, and x-ray, which is shown, coincide pin gradually
Degraded；Being coincide at 6 months, pin is completely invisible, and circular platform type support is remained in that completely, cylindrical stent partial disappearance；12 months
When, circular platform type support is invisible, and cylindrical stent is invisible.
Embodiment 4
Using new zealand white rabbit as experimental subjects, experimental group carries out vascular anastomosis, control group with the stapling apparatus of the present invention
It is coincide with conventional suture.Arteria carotis communis is cut off, row end-end coincide.Every detection means is estimated and implemented to match result
Example 1 is identical, because PLA or not when x-ray develops, therefore does not use the development observation of living animal x-ray.
Take as Figure 1 and Figure 4, a kind of biodegradable vascular anastomosis device, it is automatic right that it cooperates comprising a pair
In vascular anastomosis ring/wheel and its Special surgical instrument.
As shown in Fig. 2 the described smaller diameter end of truncated cone-shaped support 11 connects described cylindrical stent 12, its angle α is
55°；The described cylindrical stent 22 of the described smaller diameter end of truncated cone-shaped support 21 connection, its angle β is 125 °, described angle
α, β supplementary angle each other.
Its larger diameter end of truncated cone-shaped support 11 of the first described anastomosis ring/wheel 1 it is circumferentially distributed 5 identical pins 13.
Its larger diameter end of truncated cone-shaped support 21 of the second described anastomosis ring/wheel 2 it is circumferentially distributed 5 identical pins 23.
Described biodegradable vascular anastomosis ring/wheel is made up of PLA (PLA).
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and second of the first described anastomosis ring/wheel 1
The internal diameter of cylindrical stent 22 of anastomosis ring/wheel 2 is identical, inside diameter ranges 10mm.
The ratio between the length of the truncated cone-shaped vessel support support bus of two described cyclizations/wheel and cylindrical stent internal diameter are
0.8。
Described vascular anastomosis ring/wheel it is characterized in that：The thickness of the first described anastomosis ring/wheel 1 and its truncated cone-shaped blood vessel branch
The length ratio for supportting the bus of support 11 is 0.4.
Described vascular anastomosis ring/wheel it is characterized in that：The thickness of the second described anastomosis ring/wheel 2 and its truncated cone-shaped blood vessel branch
The length ratio for supportting the bus of support 21 is 0.4.
On described vascular anastomosis ring/wheel coincide pin 13, coincide pin 23 length respectively with described truncated cone-shaped blood vessel branch
It is 0.8 to support the length of the bus of support 11, the length ratio of the bus of truncated cone-shaped vessel support support 21.
Described vascular anastomosis ring/wheel it is characterized in that：The cylindrical stent 12 and round platform of the first described anastomosis ring/wheel 1
The length ratio of the bus of shape vessel support support 11 is 1.5, the cylindrical stent 22 and truncated cone-shaped of described the second anastomosis ring/wheel 2
The length ratio of the bus of vessel support support 21 is 0.6.
Choose the Special surgical instrument of corresponding size.
Experiment effect shows：
1. previous anastomotic biomethanics is detected：Postoperative 8h, 24h, 14d and 30d, 1.5cm is about including cutting containing previous anastomotic
Vascular specimen, experimental group vascular anastomosis burst pressure and breaking tension are significantly higher than control group, Anastomat hemorrhoidal circumcision ends of vessels
Intensity is higher than the identical method of suture, and Anastomat hemorrhoidal circumcision method validity is significantly higher than the identical method of suture.
2. the unobstructed assessment of scenario of previous anastomotic：With color ultrasound, angiogram respectively at postoperative 8,24,72 hours and 1,2,3,4 weeks
And 3,6, assess within 12 months the unobstructed situations of previous anastomotic of two groups of different identical methods, it is found that suture coincide group in postoperative 4 weeks
Gradually occur tube chamber diameter stenosis, more normal hemadostewnosis more than 20%, and Anastomat hemorrhoidal circumcision group does not occur for postoperative 12 months yet
The narrow situation of vessel lumen.
3. stapling apparatus degraded is determined：Postoperative 1,3,6,12 months put to death animal, take stapling apparatus：Scanning electron microscope sem point
Analyse the form of stapling apparatus different time degradation point；X-ray diffraction (XRD) is divided the degradation product composition on stapling apparatus surface
Analysis；Degradation rate is calculated with being weighed after PBS stapling apparatus after soft tissue on removing stapling apparatus, degradation curve is drawn, point
Analyse degradation rate rule.
The present invention is for coincideing between human vas, between artificial blood vessel or between human vas and artificial blood vessel, kiss
Conjunction face is coaxial geometry, identical efficient, and the area that coincide is big, improves success rate of operation and reduces previous anastomotic and collapses out now
As.
Coincide pin in bend by pressure into nearly semicircle, obvolvent is in the inner side of anastomosis ring/wheel conical surface, therefore fixed, tension
Intensity is high, is difficult to release.
Vascular anastomosis ring/take turns its pin distribution end that coincide and circumferentially may be added to that and lack 2 reinforced engagement means, in vascular anastomosis
When ring/wheel coincide, bent with identical pin, therefore coincideing available for larger blood vessel.
Prepared by present invention application absorbable material so that 1-2 can be human body drop to the vascular anastomosis ring/wheel after surgery
Solution, it is to avoid foreign matter residual risk caused by the identical method of tradition machinery.
Vascular anastomosis ring/wheel in the present invention passes through rational structure design so that vascular anastomosis ring/wheel can be after surgery
Blood vessel is kept to maintain corresponding effectively supporting time to keep vascular anastomosis ring/wheel function according to the condition of different blood vessel.
The clamping of professional apparatus collection and coincide function and one used in the present invention, simplify surgical procedure, improve operation
Efficiency.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
Member, on the premise of the inventive method is not departed from, can also make some improvement and supplement, and these are improved and supplement also should be regarded as
Protection scope of the present invention.
Claims (11)
1. a kind of vascular anastomosis device, includes vascular anastomosis ring/wheel of a pair of mutual cooperations, it is characterised in that：Described blood vessel
The the first anastomosis ring/wheel and the second anastomosis ring/wheel that anastomosis ring/wheel cooperates coaxial by a pair are constituted, and anastomosis ring/wheel includes blood
Pipe supporting support and clamp bracket；The one end open of described vessel support support is connected with described clamp bracket, described
Another end opening of vessel support support circumferentially distributed have identical pin；The vessel support of the first wherein described anastomosis ring/wheel
The outer surface of support can be nested in the inner surface of the vessel support support of described the second anastomosis ring/wheel；Described identical pin exists
It is located at homonymy after first anastomosis ring/wheel is nested with the second anastomosis ring/wheel, described clamp bracket is in the first anastomosis ring/wheel and the
It is located at offside after two anastomosis rings/wheel is nested.
2. vascular anastomosis device as claimed in claim 1, it is characterised in that：The first described anastomosis ring/wheel and second coincide
Ring/wheel vessel support support is truncated cone-shaped, and the clamp bracket of described the first anastomosis ring/wheel and the second anastomosis ring/wheel is cylinder
Shape, the described cylindrical clamp bracket of described truncated cone-shaped vessel support support smaller diameter end connection, in the truncated cone-shaped blood vessel
3 identical pins are at least distributed with supporting support larger diameter end.
3. vascular anastomosis device as claimed in claim 2, it is characterised in that：The truncated cone-shaped blood vessel of first anastomosis ring/wheel
The bus angle of the bus of supporting support and described cylindrical clamp bracket is 15 °~75 °, second anastomosis ring/wheel
The bus angle of the bus of truncated cone-shaped blood vessel clamp bracket and described cylindrical clamp bracket is 105 °~165 °, described the
The angle of the truncated cone-shaped intravascular stent bus of one anastomosis ring/wheel and described cylindrical clamp bracket bus formation and described the
The bus of the truncated cone-shaped intravascular stent of two anastomosis rings/wheel and the angle of the bus formation of described cylindrical clamp bracket are complementary.
4. vascular anastomosis device as claimed in claim 2, it is characterised in that：
The first described anastomosis ring/wheel is identical with the cylindrical stent internal diameter that the second anastomosis ring/wheel is used to clamp, inside diameter ranges
1mm~20mm；Or
The length of the truncated cone-shaped vessel support support bus of the first described anastomosis ring/wheel and the second anastomosis ring/wheel and cylinder
The ratio between clamp bracket internal diameter is 0.1~1；Or
The length of the first described anastomosis ring/wheel and the second anastomosis ring/wheel thickness and its truncated cone-shaped vessel support support bus it
Than for 0.2~0.5；Or
The length of identical pin and described truncated cone-shaped vessel support branch on the first described anastomosis ring/wheel and the second anastomosis ring/wheel
The length ratio of frame bus is 0.5~1；Or
The cylindrical clamp bracket bus of the first described anastomosis ring/wheel and the length ratio of truncated cone-shaped vessel support support bus
For 1~2；Or
The cylindrical clamp bracket bus of the second described anastomosis ring/wheel and the length ratio of truncated cone-shaped vessel support support bus
For 0.5~1.
5. vascular anastomosis device as claimed in claim 1, it is characterised in that：The identical pin of the second described anastomosis ring/wheel point
Cloth end also includes at least two reinforced engagement means, when vascular anastomosis ring/wheel coincide, is bent with identical pin.
6. vascular anastomosis device as claimed in claim 1, it is characterised in that：Described anastomosis ring/wheel is by biodegradable doctor
It is made of material.
7. a kind of anastomosis clamp for coordinating vascular anastomosis device as claimed in claim 1 to use, described anastomosis clamp includes first
Anastomosis clamp and the second anastomosis clamp, the first described anastomosis clamp and the second anastomosis clamp include gripping section, hinge section and handling section, and it is special
Levy and be：Connected between the first described anastomosis clamp and the second anastomosis clamp by dismountable mode；Section of described gripping section
Face is engaged with the section of the clamp bracket in anastomosis ring/wheel described in claim 1；Second anastomosis clamp is provided with spill
Groove, during for vascular anastomosis, by identical pin flexural deformation, realizes that blood vessel firmly coincide.
8. anastomosis clamp as claimed in claim 7, it is characterised in that：Described anastomosis clamp gripping section has a pair of clamp assemblies, institute
The clamp assemblies stated are made up of male clip assembly with female clip assembly, and male clip assembly is connected through the hinge with female clip assembly, in hinge axis
On coupled torsion circle, the clamping branch of anastomosis clamp and vascular anastomosis device as claimed in claim 1 is realized by the elastic force of torsion spring
Locking between frame；Described public clip assembly can be integrally formed on anastomosis clamp, can also be connected through the hinge in anastomosis clamp
On.
9. anastomosis clamp as claimed in claim 7, it is characterised in that：Dismountable connected mode can be hinge connection, institute
The first anastomosis clamp hinge section is fixed in the shaft end for stating hinge, and corresponding pan, the first kiss are provided with the second anastomosis clamp hinge section
Co-clip can realize the installation and dismounting of hinge in certain angle with the second anastomosis clamp, and angle is desirable 10 °~170 °.
10. anastomosis clamp as claimed in claim 8, it is characterised in that：Described clamping g. slice header is provided with location structure, described
Location structure is the structure that key and keyway are matched.
11. anastomosis clamp as claimed in claim 7, it is characterised in that described anastomosis clamp handling section is provided with circular arc graduated scale,
Described circular arc graduated scale inserts the first anastomosis clamp hole corresponding with the second anastomosis clamp handheld terminal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201710388602.2A CN107088079A (en) | 2017-05-27 | 2017-05-27 | Biodegradable vascular anastomosis ring/wheel and its Special surgical instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710388602.2A CN107088079A (en) | 2017-05-27 | 2017-05-27 | Biodegradable vascular anastomosis ring/wheel and its Special surgical instrument |
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| CN107088079A true CN107088079A (en) | 2017-08-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710388602.2A Pending CN107088079A (en) | 2017-05-27 | 2017-05-27 | Biodegradable vascular anastomosis ring/wheel and its Special surgical instrument |
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| CN109932247A (en) * | 2019-04-23 | 2019-06-25 | 四川大学华西医院 | A kind of detection device and method of Aortic Dissection blood vessel biomechanical property |
| CN110368155A (en) * | 2019-08-30 | 2019-10-25 | 河南科技大学第一附属医院 | A kind of broken ends of fractured bone vascular anastomosis support device |
| CN111436988A (en) * | 2020-05-11 | 2020-07-24 | 上海市第六人民医院 | Auxiliary device for suturing neurovascular |
| WO2020257700A3 (en) * | 2019-06-21 | 2021-02-18 | Beth Israel Deaconess Medical Center, Inc. | Lymphatic anastomosis devices |
| CN113558696A (en) * | 2021-07-08 | 2021-10-29 | 河南省人民医院 | Blood vessel anastomat for kidney transplantation operation |
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| CN113558696A (en) * | 2021-07-08 | 2021-10-29 | 河南省人民医院 | Blood vessel anastomat for kidney transplantation operation |
| CN113558696B (en) * | 2021-07-08 | 2023-05-16 | 河南省人民医院 | Vascular anastomat for kidney transplantation operation |
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