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CN109009159A - A kind of anti motion interference accelerating circuit suitable for wearable blood oxygen chip - Google Patents

A kind of anti motion interference accelerating circuit suitable for wearable blood oxygen chip Download PDF

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CN109009159A
CN109009159A CN201810816006.4A CN201810816006A CN109009159A CN 109009159 A CN109009159 A CN 109009159A CN 201810816006 A CN201810816006 A CN 201810816006A CN 109009159 A CN109009159 A CN 109009159A
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blood oxygen
signal
output end
input terminal
module
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CN109009159B (en
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蒋潘婷
郑朝霞
彭业强
吴千广
杨柯慧
夏恒炀
曾小刚
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Huazhong University of Science and Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/725Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters

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  • Spectroscopy & Molecular Physics (AREA)
  • Power Engineering (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention discloses a kind of anti motion interference accelerating circuits suitable for wearable blood oxygen chip;Module, bandpass filtering modules block, motion state judgment module, anti motion interference module, alternating-current magnitude, which are obtained, including direct current amplitude obtains module and blood oxygen saturation acquisition module;Low-pass filtering and bandpass filtering are carried out to feux rouges blood oxygen signal, infrared light blood oxygen signal, acceleration signal, obtain direct current amplitude and AC compounent respectively;Motion state is judged further according to acceleration AC signal: when moving fainter using Adaptive noise cancellation motion artifacts, being obtained alternating-current magnitude in conjunction with direct current amplitude and is obtained blood oxygen saturation;Discrete saturation degree transition structure reference signal related with blood oxygen saturation is used when moving stronger, and the discrete scanning from 1%-100% is carried out to saturation degree, the related coefficient for comparing reference signal and acceleration AC signal under different discrete saturation degrees, to directly acquire blood oxygen saturation.Area occupied of the present invention is much smaller, meets the needs of wearable application.

Description

A kind of anti motion interference accelerating circuit suitable for wearable blood oxygen chip
Technical field
The invention belongs to digital integrated circuit technology fields, are suitable for wearable blood oxygen chip more particularly, to one kind Anti motion interference accelerating circuit.
Background technique
Detecting sphygmus and blood oxygen saturation represents oxygen content level in blood of human body, is the important finger for assessing human body oxygen supply state Parameter is marked, and can effectively reflect the circulatory system of human body and the physiological status of respiratory system.It has been proposed currently on the market Wearable pulse blood oxygen monitoring device can monitor the detecting sphygmus and blood oxygen saturation of user in real time, especially for the elderly, Newborn and dyspneic patient, can remind user to see a doctor in time, to effectively avoid burst disease.However, wearable The measurement environment that pulse blood oxygen monitoring device faces is more than traditional BOLD contrast sternness, and the motion artifacts of introducing are very big, And the effect and bad in terms of anti motion interference of many wearable devices in the market.And current relatively effective anti-fortune both at home and abroad For dynamic algorithm of interference major applications on the BOLD contrast of household, algorithm amount is excessive, and the small area for being not suitable for wearable device needs Ask, and the motion artifacts that face of wearable device also it is stronger than housed device very much.Therefore, a kind of apply in wearable arteries and veins is studied Anti motion interference hardware circuit on blood oxygen of fighting chip has very big market value.
Summary of the invention
In view of the drawbacks of the prior art, the purpose of the present invention is to provide a kind of anti-fortune suitable for wearable blood oxygen chip Dynamic interference accelerating circuit, it is intended to solve prior art offer blood oxygen chip anti motion interference effect is bad or device area occupied Big problem.
The present invention provides a kind of anti motion interference accelerating circuits suitable for wearable blood oxygen chip, which is characterized in that Module, bandpass filtering modules block, motion state judgment module, anti motion interference module, alternating-current magnitude is obtained including direct current amplitude to obtain Modulus block and blood oxygen saturation obtain module.The input terminal of the direct current amplitude acquisition module and feux rouges blood oxygen signal collected (red), infrared light blood oxygen signal (ir) connects, and output end is as total output end;The direct current of feux rouges blood oxygen signal for acquisition Amplitude (red_dc), the direct current amplitude (ir_dc) of infrared light blood oxygen signal;
The input terminal of the bandpass filtering modules block and feux rouges blood oxygen signal (red) collected, infrared light blood oxygen signal (ir), acceleration signal (acc) connects, and the acceleration AC signal (acc_ac0) of output end and the motion state judge mould Block connection, feux rouges blood oxygen AC signal (red_ac0), infrared light blood oxygen AC signal (ir_ac0), the acceleration of output end are handed over Stream signal (acc_ac0) is connect with the input terminal that the anti motion interference module, the blood oxygen saturation obtain module;For obtaining Take feux rouges blood oxygen AC signal (red_ac0), infrared light blood oxygen AC signal (ir_ac0), acceleration AC signal (acc_ Ac0), while removing baseline drift and Hz noise;
The first enable signal (En1) of the output end of the motion state judgment module and the anti motion interference module The second enable signal (En2) of input terminal connection, output end is connect with the input terminal that the blood oxygen saturation obtains module;For The amplitude of acceleration AC signal (acc_ac0) is judged, enable signal is generated;
The feux rouges blood oxygen AC signal (red_ of the output end of the anti motion interference module filtered out after motion artifacts Ac1), infrared light blood oxygen AC signal (ir_ac1) is connect with the input terminal that the alternating-current magnitude obtains module;For faint Under motion state, such as static, slight jitter removes feux rouges blood oxygen AC signal (red_ac0), infrared light blood oxygen AC signal (ir_ac0) the motion artifacts ingredient in;
The alternating-current magnitude obtains the output end of module as total output end;The exchange of feux rouges blood oxygen signal for acquisition The alternating-current magnitude (ir_ac) of amplitude (red_ac), infrared light blood oxygen signal;
The blood oxygen saturation obtains the output end of module as total output end;For such as walking under strong movements state It moves, run, construct reference signal related with blood oxygen saturation, and the discrete scanning from 1%-100% is carried out to saturation degree, than The related coefficient of reference signal and acceleration AC signal (acc_ac0) under more different discrete saturation degrees, to immediately arrive at blood Oxygen saturation (SpO2);
Further, it includes: 1 rank 0.1Hz IIR low-pass filter and accumulator that the direct current amplitude, which obtains module,;Institute The output end for stating 1 rank 0.1Hz IIR low-pass filter is connect with the input terminal of the accumulator;The output end of the accumulator is made For total output end;
Further, the bandpass filtering modules block includes: 2 cascade 2 rank 0.5~5Hz IIR bandpass filters;Institute State the output end and the motion state judgment module, the anti-movement of 2 cascade 2 rank 0.5~5Hz IIR bandpass filters Interference module is connected with the input terminal that the blood oxygen saturation obtains module;
Further, the motion state judgment module includes: that average amplitude obtains circuit, comparator and 2 two choosings One selector;The output end that the average amplitude obtains circuit is connect with the input terminal of the comparator, the comparator it is defeated Outlet is connect with the input terminal of 2 alternative selectors, and the output end of 2 alternative selectors resists with described respectively Motion artifacts module is connected with the input terminal that the blood oxygen saturation obtains module.Adaptive-filtering area occupied is small, operation speed Degree is fast, but the filter effect under sharp movement state and bad, and the accuracy of discrete saturation degree transformation is high, but area occupied Greatly, arithmetic speed is slow, and the motion state judgment module is then in alignment with one kind after exactness, area, speed are comprehensively considered Optimum.
Further, the anti motion interference module includes: 20 rank LMS sef-adapting filters;The 20 rank LMS is adaptive The input module for answering the output end of filter to obtain module with the alternating-current magnitude is connect;
Further, the alternating-current magnitude obtain module include: first comparator, the second comparator, third comparator, 4th comparator, the 5th comparator, the first divider, the second divider and subtracter;The input terminal of the first comparator with Second, third output end of the anti motion interference module connects, and the output end of the first comparator is compared with described second The input terminal connection of device, the third comparator, the input terminal of the output end of second comparator and the 4th comparator Connection, the output end of the third comparator are connect with the input terminal of the 5th comparator, the output of the 4th comparator End is connect with the input terminal of first divider, the output end of the 5th comparator and the input terminal of second divider Connection, the output end of first, second divider are connect with the input terminal of the subtracter;The subtracter is by moving to right 1 Position obtains the first, second output end of module as the alternating-current magnitude;The first comparator is for detecting the anti-movement The feux rouges blood oxygen AC signal (red_ac1) filtered out after motion artifacts, the infrared light blood oxygen AC signal of interference module output end (ir_ac1) whether amplitude is greater than 0;Whether signal of second comparator for detected amplitude to be positive value is ascendant trend, Regulation is continuous to rise 10 points as ascendant trend;4th comparator sets the threshold value of peak value before for removing secondary wave crest The average value (f1+f2)/2 of two maximum;The third comparator for detected amplitude be negative value signal whether be under Drop trend is, it is specified that continuously 10 points of decline are downward trend;5th comparator sets the threshold of valley for removing time trough Value is the average value (p1+p2)/2 of the first two threshold value;First divider is for obtaining peak average value;Second division Device is for obtaining valley average value;Alternating-current magnitude (red_ac), infrared of the subtracter for the feux rouges blood oxygen signal of acquisition The alternating-current magnitude (ir_ac) of light blood oxygen signal.The alternating-current magnitude, which obtains module, can accurately extract alternating-current magnitude, exclude subwave The interference at peak, secondary trough.
Further, it includes: multiplier, accumulator, molecule acquisition circuit, denominator that the blood oxygen saturation, which obtains module, Obtain circuit and related coefficient comparison circuit;The output end of the multiplier is connect with the input terminal of the accumulator, described tired The input terminal for adding the output end of device to obtain circuit with molecule acquisition circuit, the denominator is connect, the molecule acquisition circuit, The output end that the denominator obtains circuit is connect with the input terminal of related coefficient comparison circuit, the related coefficient comparison circuit Output end is directly as total output end;The output end of the multiplier is connect with the input terminal of the accumulator, the accumulator Output end and the molecule obtain circuit, the denominator obtains the input terminal of circuit and connect, the molecule acquisition circuit, described The output end that denominator obtains circuit is connect with the input terminal of related coefficient comparison circuit, the output of the related coefficient comparison circuit Hold the output end that module is obtained as blood oxygen saturation;The multiplier is for obtaining eight references related with blood oxygen saturation Signal;The accumulator is used to obtain the summation of every group of 1024 points of eight reference signals, then is put down by moving to right 10 Mean value;It includes 1 accumulator that the molecule, which obtains circuit, for obtaining the molecule of related coefficient under different discrete saturation degrees;Institute Stating denominator and obtaining circuit includes 1 accumulator, for obtaining the denominator of related coefficient under different discrete saturation degrees;The phase relation Number comparison circuits include a comparator, absolute when related coefficient for comparing the related coefficient under different discrete saturation degrees When value is maximum, discrete saturation degree at this time is exactly detecting sphygmus and blood oxygen saturation.
Further, it includes 1 accumulator that molecule, which obtains circuit,;It includes 1 accumulator that denominator, which obtains circuit,;Phase relation Number comparison circuit includes 1 comparator.
Further, in the anti motion interference accelerating circuit, 2 low-pass filters, 3 with bandpass filters have been used With 2 anti motion interference circuits, the present invention is multiplexed above-mentioned module, can effectively reduce circuit area.
Contemplated above technical scheme through the invention, under faint motion state preferably certainly using anti-movement effects Adaptive filtering, arithmetic speed is fast, and area occupied is small;The operation of Modified Discrete saturation degree is used under strong movements state, is improved Accuracy, and opposite conventional discrete saturation degree operation, are optimized in speed and area.The measurement that hardware algorithm is realized Error rate is within 2%, circuit area 311362um2, gate equivalent circuit is 3.54 ten thousand, and clock highest frequency can achieve 56.4MHz.Compared with prior art, anti motion interference effect is preferable, and accuracy is higher, and area occupied is much smaller, and satisfaction can Dress the demand of application.
Detailed description of the invention
Fig. 1 is general structure schematic diagram provided in an embodiment of the present invention;
Fig. 2 is that direct current amplitude provided in an embodiment of the present invention obtains modular structure schematic diagram;
Fig. 3 is bandpass filtering modules block structural schematic diagram provided in an embodiment of the present invention;
Fig. 4 is motion state judgment module structural schematic diagram provided in an embodiment of the present invention;
Fig. 5 is anti motion interference modular structure schematic diagram provided in an embodiment of the present invention;
Fig. 6 is that alternating-current magnitude provided in an embodiment of the present invention obtains modular structure schematic diagram;
Fig. 7 is that blood oxygen saturation provided in an embodiment of the present invention obtains modular structure schematic diagram.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and It is not used in the restriction present invention.
In view of the drawbacks of the prior art, the purpose of the present invention is to provide a kind of anti-fortune suitable for wearable blood oxygen chip Dynamic interference accelerating circuit has the characteristics that accuracy rate is high, area occupied is small.Its main function is to collected feux rouges, red Outer smooth blood oxygen signal carries out anti motion interference processing, and acquires detecting sphygmus and blood oxygen saturation.
To achieve the above object, the present invention provides a kind of anti motion interferences suitable for wearable blood oxygen chip to accelerate electricity Road.Overall structure is as shown in Figure 1, include that direct current amplitude obtains module, bandpass filtering modules block, motion state judgment module, anti-fortune Dynamic interference module, alternating-current magnitude obtain module and blood oxygen saturation obtains module.
The direct current amplitude obtains the input terminal of module and feux rouges blood oxygen signal (red) collected, infrared light blood oxygen are believed Number (ir) connection, output end is as total output end;The direct current amplitude (red_dc) of feux rouges blood oxygen signal for acquisition, infrared light The direct current amplitude (ir_dc) of blood oxygen signal;
The input terminal of the bandpass filtering modules block and feux rouges blood oxygen signal (red) collected, infrared light blood oxygen signal (ir), acceleration signal (acc) connects, and the acceleration AC signal (acc_ac0) of output end and the motion state judge mould Block connection, feux rouges blood oxygen AC signal (red_ac0), infrared light blood oxygen AC signal (ir_ac0), the acceleration of output end are handed over Stream signal (acc_ac0) is connect with the input terminal that the anti motion interference module, the blood oxygen saturation obtain module;For obtaining Take feux rouges blood oxygen AC signal (red_ac0), infrared light blood oxygen AC signal (ir_ac0), acceleration AC signal (acc_ Ac0), while removing baseline drift and Hz noise;
The first enable signal (En1) of the output end of the motion state judgment module and the anti motion interference module The second enable signal (En2) of input terminal connection, output end is connect with the input terminal that the blood oxygen saturation obtains module;For The amplitude of acceleration AC signal (acc_ac0) is judged, enable signal is generated;
The feux rouges blood oxygen AC signal (red_ of the output end of the anti motion interference module filtered out after motion artifacts Ac1), the input terminal that feux rouges blood oxygen AC signal (ir_ac1) and the alternating-current magnitude after filtering out motion artifacts obtain module connects It connects;For under faint motion state, such as static, slight jitter to remove feux rouges blood oxygen AC signal (red_ac0), infrared light Motion artifacts ingredient in blood oxygen AC signal (ir_ac0);
The alternating-current magnitude obtains the output end of module as total output end;The exchange of feux rouges blood oxygen signal for acquisition The alternating-current magnitude (ir_ac) of amplitude (red_ac), infrared light blood oxygen signal;
The blood oxygen saturation obtains the output end of module as total output end;For such as walking under strong movements state It moves, run, construct reference signal related with blood oxygen saturation, and the discrete scanning from 1%-100% is carried out to saturation degree, than The related coefficient of reference signal and acceleration AC signal (acc_ac0) under more different discrete saturation degrees, to immediately arrive at blood Oxygen saturation (SpO2).
The structure that direct current amplitude obtains module is as shown in Figure 2, comprising: 1 rank 0.1Hz IIR low-pass filter and accumulator; The output end of the 1 rank 0.1Hz IIR low-pass filter is connect with the input terminal of the accumulator;The 1 rank 0.1Hz IIR is low Bandpass filter is used to filter out the alternating component of feux rouges blood oxygen signal (red), infrared light blood oxygen signal (ir), only retain direct current at Point, the accumulator be used for the direct currents of each group of 1024 feux rouges blood oxygen signals (red), infrared light blood oxygen signal (ir) at Divide and add up, to obtain the direct current amplitude (red_dc) of feux rouges blood oxygen signal, the direct current amplitude of infrared light blood oxygen signal (ir_dc);
The structure of bandpass filtering modules block is as shown in Figure 3, comprising: 2 cascade 2 rank 0.5~5Hz IIR bandpass filters; The output end and the motion state judgment module, the anti-fortune of 2 cascade 2 ranks, 0.5~5Hz IIR bandpass filter Dynamic interference module is connected with the input terminal that the blood oxygen saturation obtains module;For filter out the frequency other than 0.5~5Hz at Point;
The structure of motion state judgment module is as shown in Figure 4, comprising: average amplitude obtains circuit, comparator and 2 two choosings One selector;The output end that the average amplitude obtains circuit is connect with the input terminal of the comparator, the comparator it is defeated Outlet is connect with the input terminal of 2 alternative selectors, and the output end of 2 alternative selectors resists with described respectively Motion artifacts module is connected with the input terminal that the blood oxygen saturation obtains module;The average amplitude obtains circuit for obtaining The average amplitude (acc_avg) of acceleration AC signal (acc_ac0), the comparator judges for amplitude, if average amplitude (acc_avg) it is less than threshold value A, is determined as weak motion state, it is low level that comparator, which exports selection signal (sel), if average width It is worth (acc_avg) and is greater than threshold value A, is determined as sharp movement state, it is high level that comparator, which exports selection signal (sel), described 2 Alternative selector is for generating enable signal, by the control of the selection signal (sel) of the comparator output terminal alternatively device End processed, generates the first enable signal (Enl) and the second enable signal (En2), when selection signal (sel) is low level, only the One enable signal (Enl) is high level, and when selection signal (sel) is high level, only the second enable signal (En2) is high electricity Flat, the first enable signal (Enl) will make the enable signal as all anti motion interference modules, the second enable signal (En2) The enable signal of module is obtained for blood oxygen saturation.
The structure of anti motion interference module is as shown in Figure 5, comprising: 20 rank LMS sef-adapting filters;The 20 rank LMS is certainly The output end of adaptive filter is connect with the input module that the alternating-current magnitude obtains module;It is made for reducing because of motion artifacts At error;
The structure that alternating-current magnitude obtains module is as shown in Figure 6, comprising: 5 comparators, 2 dividers and 1 subtracter; The input terminal of the first comparator is connect with second, third output end of the anti motion interference module, and described first compares The output end of device is connect with the input terminal of second comparator, the third comparator, the output end of second comparator It is connect with the input terminal of the 4th comparator, the input terminal of the output end of the third comparator and the 5th comparator connects It connects, the output end of the 4th comparator is connect with the input terminal of first divider, the output end of the 5th comparator It is connect with the input terminal of second divider, the output end of first, second divider and the input terminal of the subtracter Connection;The subtracter obtains the first, second output end of module by moving to right 1 as the alternating-current magnitude;Described first Comparator is used to detect the feux rouges blood oxygen AC signal (red_ of the anti motion interference module output end filtered out after motion artifacts Ac1), whether infrared light blood oxygen AC signal (ir_ac1) amplitude is greater than 0;Second comparator is positive value for detected amplitude Signal whether be ascendant trend, it is specified that continuously rising 10 points is ascendant trend;4th comparator is secondary for removing Wave crest sets the threshold value of peak value as the average value (f1+f2)/2 of the first two maximum;The third comparator is used for detected amplitude Whether the signal for negative value is downward trend, it is specified that continuously 10 points of decline are downward trend;5th comparator is used for Time trough is removed, sets the threshold value of valley as the average value (p1+p2)/2 of the first two threshold value;First divider is for obtaining Peak average value;Second divider is for obtaining valley average value;Feux rouges blood oxygen signal of the subtracter for acquisition Alternating-current magnitude (red_ac), infrared light blood oxygen signal alternating-current magnitude (ir_ac);
Blood oxygen saturation obtain module structure as shown in fig. 7, comprises: multiplier, accumulator, molecule obtain circuit, point Mother obtains circuit and related coefficient comparison circuit;The output end of the multiplier is connect with the input terminal of the accumulator, described The output end of accumulator obtains circuit with the molecule, the input terminal of denominator acquisition circuit is connect, and the molecule obtains electricity The output end that road, the denominator obtain circuit is connect with the input terminal of related coefficient comparison circuit, and the related coefficient is more electric The output end on road is as total output end;The multiplier is used to hand over feux rouges blood oxygen AC signal (red_ac0), infrared light blood oxygen Stream signal (ir_ac0), acceleration AC signal (acc_ac0) do multiplying, generate eight references relevant to related coefficient Signal, the accumulator are used to find out the summation of every group of 1024 points about this eight reference signals, and then result moves to right 10 Position obtains average value, and the molecule obtains circuit, denominator obtains the molecule that circuit is used to construct related coefficient according to average value And denominator, and calculate the numerator value (num) under different discrete saturation degrees and denominator value (den), the related coefficient are more electric Road is used to find out related coefficient according to numerator value (num) and denominator value (den), when related coefficient maximum corresponding discrete saturation degree As detecting sphygmus and blood oxygen saturation (SpO2).
In the integrated circuit structure of the embodiment of the present invention, input signal is feux rouges blood oxygen signal (red), infrared light blood oxygen Signal (ir), acceleration signal (acc), output signal are direct current amplitude (red_dc), the infrared light blood oxygen of feux rouges blood oxygen signal The direct current amplitude (ir_dc) of signal, the alternating-current magnitude (red_ac) of feux rouges blood oxygen signal, infrared light blood oxygen signal alternating-current magnitude (ir_ac), detecting sphygmus and blood oxygen saturation (SpO2).Through ASIC verify analyze, this hardware algorithm realize measurement error rate 2% with It is interior, circuit area 311362um2, gate equivalent circuit is 3.54 ten thousand, and clock highest frequency can achieve 56.4MHz.With it is existing There is technology to compare, under the premise of ensuring accuracy, area occupied is much smaller, meets the needs of wearable application.
As it will be easily appreciated by one skilled in the art that the foregoing is merely illustrative of the preferred embodiments of the present invention, not to The limitation present invention, any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should all include Within protection scope of the present invention.

Claims (5)

1. a kind of anti motion interference accelerating circuit suitable for wearable blood oxygen chip characterized by comprising direct current amplitude obtains Modulus block, bandpass filtering modules block, motion state judgment module, anti motion interference module, alternating-current magnitude obtain module and blood oxygen is full Module is obtained with degree;
The input terminal that the direct current amplitude obtains module is used to receive feux rouges blood oxygen signal red, infrared light blood oxygen signal ir, according to Input terminal received signal exports the direct current amplitude red_dc of feux rouges blood oxygen signal and the direct current amplitude ir_ of infrared light blood oxygen signal dc;
The input terminal of the bandpass filtering modules block is for receiving feux rouges blood oxygen signal red, infrared light blood oxygen signal ir and acceleration Signal acc exports feux rouges blood oxygen AC signal red_ac0, the second output by the first output end according to input terminal received signal End output infrared light blood oxygen AC signal ir_ac0, third output end export acceleration AC signal acc_ac0;
The input terminal of the motion state judgment module is connect with the third output end of the bandpass filtering modules block, for according to institute State acceleration AC signal acc_ac0 output the first enable signal En1 and the second enable signal En2;
The control terminal of the anti motion interference module is connected to the first output end of the motion state judgment module, the anti-fortune First, second, and third input terminal of dynamic interference module is exported with the first, second, and third of the bandpass filtering modules block respectively End connection, for being handed over according to the feux rouges blood oxygen AC signal red_ac0, infrared light blood oxygen AC signal ir_ac0 and acceleration Stream signal acc_ac0 output filters out feux rouges blood oxygen AC signal red_ac1 and infrared light blood oxygen AC signal after motion artifacts ir_ac1;
The input terminal that the alternating-current magnitude obtains module is connected to the output end of the anti motion interference module, filters out for basis Feux rouges blood oxygen AC signal red_ac1 and infrared light blood oxygen AC signal ir_ac1 after motion artifacts export feux rouges blood oxygen signal Alternating-current magnitude red_ac and infrared light blood oxygen signal alternating-current magnitude ir_ac;;
The control terminal that the blood oxygen saturation obtains module is connected to the second output terminal of the motion state judgment module, described Blood oxygen saturation obtain the first, second, and third input terminal of module respectively with the first, second of the bandpass filtering modules block and The connection of third output end, for according to the feux rouges blood oxygen AC signal red_ac0, infrared light blood oxygen AC signal ir_ac0 and Acceleration AC signal acc_ac0 exports oxygen saturation signal.
2. anti motion interference accelerating circuit as described in claim 1, which is characterized in that the motion state judgment module packet Include: average amplitude obtains circuit, comparator and 2 alternative selectors;
The average amplitude obtains input terminal of the input terminal of circuit as the motion state judgment module, the comparator Input terminal is connect with the output end that the average amplitude obtains circuit, the output end of the comparator and 2 alternative selectors Input terminal connection, the output ends of 2 alternative selectors is first defeated respectively as the motion state judgment module Outlet and second output terminal.
3. anti motion interference accelerating circuit as claimed in claim 2, which is characterized in that the average amplitude obtains circuit and includes 1 accumulator;
The accumulator is used to obtain the sum of acceleration AC signal acc_ac0, then by moving to right 10 acquisition amplitudes.
4. anti motion interference accelerating circuit as described in any one of claims 1-3, which is characterized in that the alternating-current magnitude obtains Module includes: first comparator, the second comparator, third comparator, the 4th comparator, the 5th comparator, the first divider, Double division method device and subtracter;
The input terminal of first comparator is connect with second, third output end of the anti motion interference module, and described first compares The output end of device is connect with the input terminal of the second comparator, third comparator, the output end of second comparator and the 4th ratio Input terminal compared with device connects, and the output end of the third comparator is connect with the input terminal of the 5th comparator, and the described 4th compares The output end of device is connect with the input terminal of first divider, the output end and second divider of the 5th comparator Input terminal connection, the output end of first, second divider connect with the input terminal of the subtracter;The subtracter is logical It crosses and moves to right 1 the first, second output end for obtaining module as the alternating-current magnitude.
5. anti motion interference accelerating circuit according to any one of claims 1-4, which is characterized in that the blood oxygen saturation obtains Modulus block includes: multiplier, accumulator, molecule obtains circuit, denominator obtains circuit and related coefficient comparison circuit;
The output end of the multiplier is connect with the input terminal of the accumulator, and the output end of the accumulator is obtained with the molecule Sense circuit, the denominator obtain the input terminal connection of circuit, and the molecule obtains circuit, the denominator obtains the output end of circuit It is connect with the input terminal of related coefficient comparison circuit, the output end of the related coefficient comparison circuit is obtained as blood oxygen saturation The output end of module;
The multiplier is for obtaining eight reference signals related with blood oxygen saturation;
The accumulator is used to obtain the summation of every group of 1024 points of eight reference signals, then is averaged by moving to right 10 Value;
The molecule obtains the molecule that circuit is used to obtain related coefficient under different discrete saturation degrees;
The denominator obtains the denominator that circuit is used to obtain related coefficient under different discrete saturation degrees;
The related coefficient comparison circuit is used to compare the related coefficient under different discrete saturation degrees, when the absolute value of related coefficient Corresponding discrete saturation degree is detecting sphygmus and blood oxygen saturation when maximum.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118214396A (en) * 2024-04-09 2024-06-18 武汉康诺芯半导体有限公司 Anti-motion interference processing circuit suitable for blood oxygen extraction chip

Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720734B2 (en) * 2002-08-08 2004-04-13 Datex-Ohmeda, Inc. Oximeter with nulled op-amp current feedback
CN1729933A (en) * 2004-08-05 2006-02-08 香港理工大学 Portable health-care monitoring arrangement with motion compensation function and its compensation method
CN101632588A (en) * 2009-08-04 2010-01-27 中国人民解放军第四军医大学 Measurement method of blood oxygen saturation for eliminating motion interference
CN102499694A (en) * 2011-09-22 2012-06-20 中国人民解放军第三军医大学野战外科研究所 Method for eliminating interference to blood oxygen saturation monitoring
CN102551736A (en) * 2012-01-19 2012-07-11 西北工业大学 Light sensing system
WO2012158420A1 (en) * 2011-05-17 2012-11-22 Zarlink Semiconductor Ab A signal acquisition circuit for detecting a wanted signal in the presence of an unwanted signal
CN103230267A (en) * 2013-05-14 2013-08-07 北京理工大学 Anti-movement-interference extraction method for pulse rates
US20130324818A1 (en) * 2008-10-07 2013-12-05 Covidien Lp Non-interfering physiological sensor system
US20140221789A1 (en) * 2000-06-16 2014-08-07 Bodymedia, Inc. System for monitoring and presenting health, wellness and fitness trend data having user selectable parameters
CN104287712A (en) * 2014-09-28 2015-01-21 青岛蓝图文化传播有限公司市南分公司 Wireless communication bracelet
CN104622478A (en) * 2013-11-11 2015-05-20 达尔生技股份有限公司 Blood oxygen meter jitter determination method and intelligent anti-jitter blood oxygen measuring device
CN204428045U (en) * 2014-12-08 2015-07-01 华南理工大学 Based on the blood oxygen saturation checkout gear of wearable device
CN104856659A (en) * 2015-05-28 2015-08-26 中国科学院合肥物质科学研究院 Myocardium blood oxygen supply/demand situation dynamic monitoring system based on accelerated speed and pulse and early-warning method
CN104997518A (en) * 2015-06-25 2015-10-28 广州视源电子科技股份有限公司 Method and system for counteracting motion interference of blood oxygen measuring equipment
CN106413530A (en) * 2014-05-28 2017-02-15 皇家飞利浦有限公司 Motion artifact reduction using multi-channel ppg signals
CN106419850A (en) * 2016-11-03 2017-02-22 国家康复辅具研究中心 Dynamic brain function detection method and system based on near infrared spectrum and blood pressure information
WO2017218598A1 (en) * 2016-06-13 2017-12-21 Performance Athlytics Wearable athletic monitoring using digital modulation
KR20170141093A (en) * 2016-06-14 2017-12-22 한선애 Detachable bio sensor for carotid and measuring device
CN107595296A (en) * 2017-09-19 2018-01-19 广东乐心医疗电子股份有限公司 Blood oxygen saturation detection method and blood oxygen detection device for eliminating motion interference
WO2018057937A1 (en) * 2016-09-22 2018-03-29 Apple Inc. Systems and methods for determining physiological signals using ambient light
CN107874765A (en) * 2017-11-06 2018-04-06 成都菲斯普科技有限公司 Medical bracelet and method of self compensation with self-compensating function
US20180160954A1 (en) * 2016-12-14 2018-06-14 Hon Hai Precision Industry Co., Ltd. Pulse oximeter

Patent Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140221789A1 (en) * 2000-06-16 2014-08-07 Bodymedia, Inc. System for monitoring and presenting health, wellness and fitness trend data having user selectable parameters
US6720734B2 (en) * 2002-08-08 2004-04-13 Datex-Ohmeda, Inc. Oximeter with nulled op-amp current feedback
CN1729933A (en) * 2004-08-05 2006-02-08 香港理工大学 Portable health-care monitoring arrangement with motion compensation function and its compensation method
US20130324818A1 (en) * 2008-10-07 2013-12-05 Covidien Lp Non-interfering physiological sensor system
CN101632588A (en) * 2009-08-04 2010-01-27 中国人民解放军第四军医大学 Measurement method of blood oxygen saturation for eliminating motion interference
WO2012158420A1 (en) * 2011-05-17 2012-11-22 Zarlink Semiconductor Ab A signal acquisition circuit for detecting a wanted signal in the presence of an unwanted signal
CN102499694A (en) * 2011-09-22 2012-06-20 中国人民解放军第三军医大学野战外科研究所 Method for eliminating interference to blood oxygen saturation monitoring
CN102551736A (en) * 2012-01-19 2012-07-11 西北工业大学 Light sensing system
CN103230267A (en) * 2013-05-14 2013-08-07 北京理工大学 Anti-movement-interference extraction method for pulse rates
CN104622478A (en) * 2013-11-11 2015-05-20 达尔生技股份有限公司 Blood oxygen meter jitter determination method and intelligent anti-jitter blood oxygen measuring device
CN106413530A (en) * 2014-05-28 2017-02-15 皇家飞利浦有限公司 Motion artifact reduction using multi-channel ppg signals
CN104287712A (en) * 2014-09-28 2015-01-21 青岛蓝图文化传播有限公司市南分公司 Wireless communication bracelet
CN204428045U (en) * 2014-12-08 2015-07-01 华南理工大学 Based on the blood oxygen saturation checkout gear of wearable device
CN104856659A (en) * 2015-05-28 2015-08-26 中国科学院合肥物质科学研究院 Myocardium blood oxygen supply/demand situation dynamic monitoring system based on accelerated speed and pulse and early-warning method
CN104997518A (en) * 2015-06-25 2015-10-28 广州视源电子科技股份有限公司 Method and system for counteracting motion interference of blood oxygen measuring equipment
WO2017218598A1 (en) * 2016-06-13 2017-12-21 Performance Athlytics Wearable athletic monitoring using digital modulation
KR20170141093A (en) * 2016-06-14 2017-12-22 한선애 Detachable bio sensor for carotid and measuring device
WO2018057937A1 (en) * 2016-09-22 2018-03-29 Apple Inc. Systems and methods for determining physiological signals using ambient light
CN106419850A (en) * 2016-11-03 2017-02-22 国家康复辅具研究中心 Dynamic brain function detection method and system based on near infrared spectrum and blood pressure information
US20180160954A1 (en) * 2016-12-14 2018-06-14 Hon Hai Precision Industry Co., Ltd. Pulse oximeter
CN107595296A (en) * 2017-09-19 2018-01-19 广东乐心医疗电子股份有限公司 Blood oxygen saturation detection method and blood oxygen detection device for eliminating motion interference
CN107874765A (en) * 2017-11-06 2018-04-06 成都菲斯普科技有限公司 Medical bracelet and method of self compensation with self-compensating function

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
YAN, JIAYUN,ET AL: "Research on an anti-motion interference algorithm of blood oxygen saturation based on AC and DC analysis", 《TECHNOLOGY AND HEALTH CARE》 *
ZHAOXIA ZHENG等: "Low Perfusion Algorithm used in Wearable Oximeter and Hardware Acceleration", 《2016 IEEE INTERNATIONAL CONFERENCE ON ELECTRON DEVICES AND SOLID-STATE CIRCUITS》 *
龚渝顺等: "一种抗干扰穿戴式血氧饱和度监测仪的研制", 《传感技术学报》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118214396A (en) * 2024-04-09 2024-06-18 武汉康诺芯半导体有限公司 Anti-motion interference processing circuit suitable for blood oxygen extraction chip

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