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FR2417094A1 - Multiple, automated immunoassay method - with reaction carried out in removable open=ended syringe tips - Google Patents

Multiple, automated immunoassay method - with reaction carried out in removable open=ended syringe tips

Info

Publication number
FR2417094A1
FR2417094A1 FR7804069A FR7804069A FR2417094A1 FR 2417094 A1 FR2417094 A1 FR 2417094A1 FR 7804069 A FR7804069 A FR 7804069A FR 7804069 A FR7804069 A FR 7804069A FR 2417094 A1 FR2417094 A1 FR 2417094A1
Authority
FR
France
Prior art keywords
tip
insolubilised
syringe
amt
pair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7804069A
Other languages
French (fr)
Other versions
FR2417094B3 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MILLES LAUGHTON
Original Assignee
MILLES LAUGHTON
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MILLES LAUGHTON filed Critical MILLES LAUGHTON
Priority to FR7804069A priority Critical patent/FR2417094A1/en
Publication of FR2417094A1 publication Critical patent/FR2417094A1/en
Application granted granted Critical
Publication of FR2417094B3 publication Critical patent/FR2417094B3/fr
Granted legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Determination of the amt. of analyte (A) in a sample, where (A) is one of a pair of specific bindable substances, and one member of the pair is insolubilised, uses as detectant (D) one member of the pair giving a measureable signal proportion to the number of molecules of (D) present. The improvement is that first a soln. or (A) is drawn, by syringe, into an open-ended tip, detachably mounted on the syringe, which contains the insolubilised component. (where (A) can be bound to the tip it may be the insolubilised component). A soln. of (D), and other reagents or wash solns. is supplied to the tip (from an outside source or from the syringe), then the solns. removed from the tip by the syringe. The amt. of (D) insolubilised in, or remove from, the tip is then measured to determine the amt. of (A). Process is esp. for immunoassay procedures such as radioimmunoassay (RIA), immunoradiometric assay (IRMA) or 2-site IRMA. The system requires minimal supervision and avoids fluctuating conditions.
FR7804069A 1978-02-14 1978-02-14 Multiple, automated immunoassay method - with reaction carried out in removable open=ended syringe tips Granted FR2417094A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7804069A FR2417094A1 (en) 1978-02-14 1978-02-14 Multiple, automated immunoassay method - with reaction carried out in removable open=ended syringe tips

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7804069A FR2417094A1 (en) 1978-02-14 1978-02-14 Multiple, automated immunoassay method - with reaction carried out in removable open=ended syringe tips

Publications (2)

Publication Number Publication Date
FR2417094A1 true FR2417094A1 (en) 1979-09-07
FR2417094B3 FR2417094B3 (en) 1980-10-17

Family

ID=9204551

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7804069A Granted FR2417094A1 (en) 1978-02-14 1978-02-14 Multiple, automated immunoassay method - with reaction carried out in removable open=ended syringe tips

Country Status (1)

Country Link
FR (1) FR2417094A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0134605A1 (en) * 1980-12-22 1985-03-20 Commonwealth Serum Laboratories Commission Device for detecting antigens and antibodies
FR3067814A1 (en) * 2017-06-20 2018-12-21 Biomerieux METHOD FOR APPLYING, ON A SOLID SUPPORT, AT LEAST ONE MOLECULAR BINDING PARTNER
WO2020234617A1 (en) 2019-05-22 2020-11-26 Biomerieux Methods and systems for manufacturing a production assay reactor

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0134605A1 (en) * 1980-12-22 1985-03-20 Commonwealth Serum Laboratories Commission Device for detecting antigens and antibodies
FR3067814A1 (en) * 2017-06-20 2018-12-21 Biomerieux METHOD FOR APPLYING, ON A SOLID SUPPORT, AT LEAST ONE MOLECULAR BINDING PARTNER
WO2018234682A1 (en) 2017-06-20 2018-12-27 bioMérieux Method for applying, on a solid support, at least one binding partner to a molecule
WO2020234617A1 (en) 2019-05-22 2020-11-26 Biomerieux Methods and systems for manufacturing a production assay reactor

Also Published As

Publication number Publication date
FR2417094B3 (en) 1980-10-17

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