GB1213211A - Pharmaceutical compositions for combatting angina - Google Patents
Pharmaceutical compositions for combatting anginaInfo
- Publication number
- GB1213211A GB1213211A GB6393/68A GB639368A GB1213211A GB 1213211 A GB1213211 A GB 1213211A GB 6393/68 A GB6393/68 A GB 6393/68A GB 639368 A GB639368 A GB 639368A GB 1213211 A GB1213211 A GB 1213211A
- Authority
- GB
- United Kingdom
- Prior art keywords
- isopropylamino
- ethanol
- propanol
- angina
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 206010002383 Angina Pectoris Diseases 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940124549 vasodilator Drugs 0.000 abstract 2
- 239000003071 vasodilator agent Substances 0.000 abstract 2
- FCEAYLHORVBNMO-UHFFFAOYSA-N 1-(3,4-dichlorophenyl)-2-(propan-2-ylamino)propan-1-ol Chemical compound CC(C)NC(C)C(O)C1=CC=C(Cl)C(Cl)=C1 FCEAYLHORVBNMO-UHFFFAOYSA-N 0.000 abstract 1
- KVMZGYOHNZWGRG-UHFFFAOYSA-N 1-cyclohexa-1,5-dien-1-yl-2-(propan-2-ylamino)ethanol Chemical compound CC(C)NCC(O)C1=CCCC=C1 KVMZGYOHNZWGRG-UHFFFAOYSA-N 0.000 abstract 1
- TWUSDDMONZULSC-UHFFFAOYSA-N 2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol Chemical compound COC1=CC=C(OC)C(C(O)C(C)NC(C)(C)C)=C1 TWUSDDMONZULSC-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N EtOH Substances CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- TZRXHJWUDPFEEY-UHFFFAOYSA-N Pentaerythritol Tetranitrate Chemical compound [O-][N+](=O)OCC(CO[N+]([O-])=O)(CO[N+]([O-])=O)CO[N+]([O-])=O TZRXHJWUDPFEEY-UHFFFAOYSA-N 0.000 abstract 1
- 239000000026 Pentaerythritol tetranitrate Substances 0.000 abstract 1
- PAZJSJFMUHDSTF-UHFFFAOYSA-N alprenolol Chemical compound CC(C)NCC(O)COC1=CC=CC=C1CC=C PAZJSJFMUHDSTF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002981 blocking agent Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960005450 eritrityl tetranitrate Drugs 0.000 abstract 1
- SNFOERUNNSHUGP-ZXZARUISSA-N erythrityl tetranitrate Chemical compound [O-][N+](=O)OC[C@@H](O[N+]([O-])=O)[C@@H](O[N+]([O-])=O)CO[N+]([O-])=O SNFOERUNNSHUGP-ZXZARUISSA-N 0.000 abstract 1
- MOYKHGMNXAOIAT-JGWLITMVSA-N isosorbide dinitrate Chemical compound [O-][N+](=O)O[C@H]1CO[C@@H]2[C@H](O[N+](=O)[O-])CO[C@@H]21 MOYKHGMNXAOIAT-JGWLITMVSA-N 0.000 abstract 1
- 229960000201 isosorbide dinitrate Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- UAORFCGRZIGNCI-UHFFFAOYSA-N nifenalol Chemical compound CC(C)NCC(O)C1=CC=C([N+]([O-])=O)C=C1 UAORFCGRZIGNCI-UHFFFAOYSA-N 0.000 abstract 1
- 229960004321 pentaerithrityl tetranitrate Drugs 0.000 abstract 1
- ZMRUPTIKESYGQW-UHFFFAOYSA-N propranolol hydrochloride Chemical compound [H+].[Cl-].C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 ZMRUPTIKESYGQW-UHFFFAOYSA-N 0.000 abstract 1
- NXQMNKUGGYNLBY-UHFFFAOYSA-N toliprolol Chemical compound CC(C)NCC(O)COC1=CC=CC(C)=C1 NXQMNKUGGYNLBY-UHFFFAOYSA-N 0.000 abstract 1
- 229940125725 tranquilizer Drugs 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
1,213,211. Medicines for angina. H. I. RUSSEK. 8 Feb., 1968 [14 Feb., 1967; 29 Jan., 1968], No. 6393/68 Heading A5B. Compositions for the treatment of angina pectoris comprise a carrier, a vasodilator and a #-andrenergic recepter blocking agent, the vasodilator being selected from: pentaerythritol tetranitrate, erythrityl tetranitrate and isosorbide dinitrate; and the #-andrenergic blocker is selected from: 1-(3,4-dichlorophenoyl)-2-isopropylamino-1-ethanol, 1-(3,4-dihydrophenyl)-2 -isopropylamino-1-ethanol, 1-(2,5-dimethoxyphenyl)-2-methyl-2-t-butylamino-1-ethanol, 1- (3,4-dichlorophenyl)-2-methyl-2-isopropylamino -1-ethanol, 1-(3-tolyloxy)-3-isopropylamino-2- propanol, 1-(5,6,7,8-tetrahydronaphtha-2-yl)-2- s-butylamino ethanol, 1-(2-allylphenoxy)-3-isopropylamino-2-propanol, 1-(p-nitrophenyl)-2- isopropylaminoethanol, 1-(p-nitrophenyl)-2-nbutylaminoethanol and 1-(isopropylamino)-3- (1-naphthyloxy)-2-propanol hydrochloride. A tranquilizer may also be present.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61592567A | 1967-02-14 | 1967-02-14 | |
| US70107968A | 1968-01-29 | 1968-01-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1213211A true GB1213211A (en) | 1970-11-25 |
Family
ID=27087635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6393/68A Expired GB1213211A (en) | 1967-02-14 | 1968-02-08 | Pharmaceutical compositions for combatting angina |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE710731A (en) |
| DE (1) | DE1667909A1 (en) |
| FR (1) | FR7344M (en) |
| GB (1) | GB1213211A (en) |
| NL (1) | NL6801917A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007065303A1 (en) * | 2005-12-09 | 2007-06-14 | Beijing Kangbeide Pharmaceutical Technology Development Co., Ltd. | Transdermal patch containing isosorbide dinitrate and bisoprolol |
-
1968
- 1968-02-08 GB GB6393/68A patent/GB1213211A/en not_active Expired
- 1968-02-09 NL NL6801917A patent/NL6801917A/xx unknown
- 1968-02-13 BE BE710731D patent/BE710731A/xx unknown
- 1968-02-13 FR FR139658A patent/FR7344M/fr not_active Expired
- 1968-02-14 DE DE19681667909 patent/DE1667909A1/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007065303A1 (en) * | 2005-12-09 | 2007-06-14 | Beijing Kangbeide Pharmaceutical Technology Development Co., Ltd. | Transdermal patch containing isosorbide dinitrate and bisoprolol |
| US8071125B2 (en) | 2005-12-09 | 2011-12-06 | Beijing Kangbeide Pharmaceutical Technology Development Co., Ltd. | Transdermal patch containing isosorbide dinitrate and bisoprolol |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1667909A1 (en) | 1971-06-16 |
| FR7344M (en) | 1969-10-13 |
| BE710731A (en) | 1968-08-13 |
| NL6801917A (en) | 1968-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |