JP2005170828A - Fabric for patch and patch - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To prepare a patch which is hard to give good workability, when adhered to a body, is flexible, when pulled on adhesion or subjected to the movements of the body, such as bending or stretching movements, after adhered to the body, is hardly peeled, and acts as a patch giving a good wearing sense, and to provide a fabric for the patch. <P>SOLUTION: The fabric for the patch is characterized in that the shapes of fibers constituting the elastic fabric having elasticity in at least one direction are partially fixed. The patch is characterized by coating an adhesive containing a medicine on one side of the fabric for the patch. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

  The present invention relates to a patch fabric and a patch used for a haptic agent, a plaster agent and the like. More particularly, the present invention relates to a patch fabric and a patch excellent in handleability when a stretchable patch having good followability such as elbows, knees, neck and flank is applied to the body.

  In recent years, a patch fabric and a patch have been developed that follow a region with a large bend such as the elbow, knee, neck, and flank, and a region where the skin moves complicatedly, such as the neck and flank, and is difficult to peel off (Patent Documents 1 to 3) 9). These patch fabrics are devised so that the fabric expands and contracts in order to improve the followability with the application site, and are made into thin and flexible fabrics, and the coating drug layer follows the fabrics. As such, the drug composition has been devised. Certainly, when the patch is affixed to the body, it follows the movement of the body, is difficult to peel off, and has a good feeling of wearing, but since the patch itself is very flexible, The work had the serious problem of becoming extremely difficult.

For example, if the liner film on the drug part of the patch is peeled off, there is no form stability due to the lack of elasticity in the patch, and the adhesive coated surfaces that stick together will not stick well when sticking to the body In many cases, the patch is often wasted. In addition, since such patches are often used by elderly people, it is an urgent need to improve the handleability.
JP-A-63-122621 JP-A-1-121214 Japanese Patent Laid-Open No. 3-161433 Japanese Patent Laid-Open No. 3-161436 Japanese Patent No. 2726948 Japanese Patent No. 2729520 Japanese Patent No. 2879228 JP 2002-1855 A JP 2002-4146 A

  In view of the background of the prior art, the present invention is advantageous in that the patch is hard and has good workability when applied to the body, but the tension of the patch when applied and the bending of the body after being applied By applying an operation such as expansion and contraction, the patch becomes flexible, and it is difficult to peel off and provides a patch fabric and patch that function as a patch having a good wearing feeling.

  The present invention employs the following means in order to solve such problems. That is, the patch fabric of the present invention is characterized in that the fibers constituting the stretchable fabric having stretchability in at least one direction are partially fixed in shape. The patch is characterized in that a pressure-sensitive adhesive containing a drug is applied to one side of the patch fabric.

  ADVANTAGE OF THE INVENTION According to this invention, the base fabric for patches and a patch which have both the sticking workability | operativity of a patch and the wearability after sticking can be provided easily.

  The present invention has the above-mentioned problems, that is, when the patch is applied to the body, the patch is hard and has good workability, but the tension of the patch when applied, bending of the body after application, expansion and contraction, etc. By applying an operation, the patch becomes flexible, and it is difficult to peel off and the patch fabric that functions as a patch with good wearing feeling is studied earnestly. By fixing the form by partially heat-fixing the constituent fibers, the fabric itself is hardened. However, when a specific stretching force is applied, the form fixing force that restrains the fabric is released. The present inventors have investigated that this problem can be solved at once by providing a function of returning the stretchable fabric to the original flexible and stretchable fabric. That is, according to the present invention, it is possible to provide a patch fabric that can satisfy both handleability and fit for the first time.

  Examples of the fibers constituting the stretchable fabric of the present invention include polyester fibers, polyethylene fibers, polypropylene fibers, polyamide fibers, polyvinyl alcohol fibers, polyvinyl chloride fibers, and other synthetic fibers, rayon, acetate and other half fibers. Natural fibers such as synthetic fibers, synthetic fibers, cotton, hemp, silk, wool can be used, and the structure constituting the stretchable fabric is at least one selected from woven fabrics, knitted fabrics and non-woven fabrics. Can be used.

  As a method for forming such a stretchable fabric, for example, a polyethylene terephthalate fiber will be described as a representative example. A crimp is formed on a yarn by false twisting, a side-by-side composite, a mix of yarns having different shrinkage rates, or the like. The yarn is stretched and recoverable to form a fabric with the yarn. In such a fabric structure, a knitted fabric and / or a nonwoven fabric is preferably used as a fabric that expands and contracts in at least one direction, preferably in multiple directions.

  The stretchable fabric of the present invention was heat-pressed by calendering and hardened to improve the handleability, and was temporarily heat-pressed when an extension force was applied to the stretchable fabric. The restraining force of the portion is loosened so that the stretchable fabric is softened.

  Such calendering can be generally used for fabric processing, and is not particularly limited, but is a pair of a heated metal roll and a cooled paper roll or felt roll. Are preferably used. The temperature of the heating roll is 90 to 200 ° C, preferably 120 to 180 ° C, and the pressure for pressurization is 5 to 100 t / cm, preferably 10 to 50 t / cm. Such calendering can be employed in a process capable of exhibiting the intended effect, such as after forming a fabric, after a raw machine or after heat setting. In addition, resin can also be adhered in order to adjust hardness before or after such calendering.

  The stretchable fabric that has been hardened by pressure treatment and hardened temporarily and fixed in shape by being heat-fixed is bonded to a necessary part of the body, and then the part is bent and stretched to restrain the fabric tissue. The applied force is released to soften, and the texture changes so as to fit the body part accurately and prevent peeling. The force acting on the stretchable fabric by bending and stretching of elbows, knees, neck, flank, etc. is generally said to have a stretch ratio of 20-50% of the stretchable fabric. It is preferable to use one having an elongation of 50 to 100%.

  The patch fabric of the present invention may be softened when it is stretched in at least one direction, preferably 5% or more, more preferably 10% or more. What to do is good. In short, it is softened by stretching less than 5%, more preferably 10% or more, which is smaller than the stretch size of each part of the body, and sufficiently softened when 20-50% stretches in each part of the body. It is important to select calendar processing conditions that can be used.

  As an adhesive containing a drug to be applied to such a patch fabric, the drug is absorbed into the body through the skin and exhibits a pharmacological effect, absorbs the heat of the body, or generates heat to generate heat. Although it will not specifically limit if it exists, For example, an anti-inflammatory agent, an analgesic, a local stimulant, an antihistamine, a local anesthetic, a blood circulation promoter, a tranquilizer, etc. are illustrated. Examples of the adhesive component include, but are not particularly limited to, natural rubber-based, polyisoprene-based, polyisobutylene-based, acrylate-based, and methacrylic ester-based polymers. Examples of the method of applying the adhesive containing the agent to the fabric include, for example, a method in which the adhesive is dissolved in a solvent and applied and heat-treated to dry the solvent, a method in which the solvent is melted and extruded onto an elastic fabric from an extruder A known method can be used and is not particularly limited.

  Since the patch of the present invention is composed of such a fabric for patch, the handleability is good until it is applied to the body part, and after the application, the elasticity of the body part is good and the elasticity is good. Is.

EXAMPLES Hereinafter, although an Example demonstrates this invention in detail, this invention is not limited to these. Moreover, the quality evaluation in an Example was implemented with the following method.
<Flexibility of fabric>
Based on the cantilever method defined in JIS L 1096-1979 6.19.1A method, the bending resistance in the vertical direction was measured. The smaller the value, the more flexible. The unit is expressed in (mm).

Examples 1-6, Comparative Example 1
A 56 dtex, 36 filament false twisted yarn made of polyethylene terephthalate was used to knit with a smooth structure, scoured at 90 ° C. by liquid flow dyeing, and dyed beige at 130 ° C. The knitted fabric was dehydrated and opened, and then set with a pin tenter at a temperature of 170 ° C. to make a knitted fabric that stretched in multiple directions (well / course 44/57 pieces / 2.54 cm, weight 102 g / m ² ). The flexibility of the dyed knitted fabric was 24 mm. Table 1 shows the result of evaluating flexibility after calendering and fixing the form under the following conditions.

(Calendar processing)
The heat treatment was carried out at a speed of 8 m / min by changing the temperature and linear pressure with a pair of a 30φ stainless steel roll capable of heating and a cooled paper roll having the same diameter.

(Adhesive treatment)
A natural rubber-based adhesive compounded with an analgesic agent was applied at a temperature of 135 ° C. with a T-die extruder to a thickness of 10 μm, and a polyethylene terephthalate film with a thickness of 3.5 μm was laminated as a liner on the adhesive layer.

(Handability test)
Five healthy boys in their 60s (Panels 1 to 5) were selected, and the following evaluations were made in the order of Examples and Comparative Examples.

Evaluation (1) The workability when removing the liner of the patch and whether the adhesive layers were hindered after the liner was peeled off were examined and displayed according to the following evaluation criteria.
○: Work without problems.
Δ: Neither can be said ×: There is a work trouble.

Evaluation (2) Ease of application was evaluated when the patch with the liner removed was applied to the right neck (from neck to shoulder).
○: Easy to paste.
Δ: Neither can be said.
X: It is difficult to paste.

Evaluation (3) After being applied to the neck, the fitting condition such as fit and peeling was evaluated after 5 hours.
○: No problem.
Δ: The surroundings turn up.
X: peeling off.

  As is clear from Table 1, in Examples 1 to 6, the patch base fabric in the state where the adhesive was applied was hard-finished as compared with that in Comparative Example 1, so that the liner It can be seen that the film can be easily peeled off and affixed to a predetermined site, and the base fabric is softened by stretching at the time of affixing and the expanding and contracting action of the site after affixing.

Claims (5)

A patch fabric, wherein the fibers constituting the stretchable fabric having stretchability in at least one direction are partially fixed in form. The patch fabric according to claim 1, wherein the form fixation is heat fixation. The patch fabric according to claim 1 or 2, wherein the form fixation is dissociated when the patch fabric is stretched by 5% or more. A patch comprising a drug-containing adhesive applied to one side of the patch fabric according to any one of claims 1 to 3. A method for producing a patch fabric, characterized in that a stretchable fabric having stretchability in at least one direction is heated and pressurized, and the fibers constituting the fabric are partially heat-set and fixed in form. .