JP6347632B2 - Guide wire - Google Patents

Description

  The present invention relates to a guide wire.

  The guide wire introduces and guides catheters used for treatment of difficult surgical sites or treatment for the purpose of minimally invasive to the human body, angiographic examination and treatment in heart disease, etc. Is used.

  For example, when PCI (Percutaneous Coronary Intervention) is performed, the distal end of the guide wire protrudes from the distal end of the balloon catheter under fluoroscopy, and is the target site together with the balloon catheter. Insert the coronary artery (coronary artery) just before the stenosis, then pass the tip of the guide wire through the stenosis, then guide the balloon catheter balloon along the guide wire to the stenosis, and expand the balloon to stenosis A treatment that spreads the part and secures blood flow is performed.

  For example, in order to insert a guide wire from the femoral artery by the Seldinger method and advance to the coronary artery via the aorta, aortic arch, coronary artery mouth, the guide wire has flexibility (followability) for following the blood vessel, It is preferable that the torque transmission performance is such that the torque applied on the proximal end side of the guide wire can be reliably transmitted to the distal end side.

  In addition, in order to select and advance an appropriate branch of a branch portion such as a coronary artery, the tip portion of the guide wire may be shaped to match the shape of the branch portion. This shaping is usually performed by a doctor or the like with a finger at the time of treatment, and is called reshaping.

  In particular, when the distal end of the guide wire is inserted into the distal coronary artery, the desired branch cannot be selected with the conventional pre-shaped angle-shaped or J-shaped distal shape, and the distal end of the guide wire cannot be selected. In many cases, it is changed into a desired shape and reinserted. If the tip shape of the guide wire still does not match, the guide wire must be removed from the catheter, reshaped, and inserted. Therefore, the distal end portion of the guide wire needs to have flexibility as well as reshapability.

  By the way, in order to obtain the flexibility of a front-end | tip part, the guide wire in which the flat part provided in the front-end | tip part makes plate shape is known (for example, refer patent document 1).

  In the guide wire described in Patent Document 1, since the flat portion has a plate shape, it can be easily bent in the thickness direction. That is, this flat part is rich in flexibility. However, since the flat portion has sufficient flexibility, the torsional rigidity is relatively low in the flat portion having the plate shape. Thereby, there exists a possibility that torque transferability may become inadequate. Thus, it is difficult for the conventional guide wire to achieve both flexibility and torque transmission.

JP 2012-5722 A

  An object of the present invention is to provide a guide wire capable of obtaining an excellent torque transmission property while ensuring sufficient flexibility at a distal end portion.

Such an object is achieved by the present inventions (1) to ( 9 ) below.
(1) A wire body having a plate-like flat plate portion is provided at the tip,
The flat plate portion is composed of a first flat plate forming portion and a second flat plate forming portion made of different materials,
One flat plate forming portion of the first flat plate forming portion and the second flat plate forming portion is provided over the entire region in the width direction of the flat plate portion , and the entire region in the thickness direction of the flat plate portion. guide wire, characterized in that provided over.

  (2) One of the first flat plate forming portion and the second flat plate forming portion has at least one embedded portion embedded in the other flat plate forming portion (1) ) Guide wire.

  (3) The guide wire according to (2), wherein the embedded portion extends in a direction intersecting with a longitudinal direction of the wire body.

(4) A plurality of the embedded portions are provided,
The guide wire according to (2) or (3), wherein the embedded portions have different inclination directions with respect to the longitudinal direction of the wire body and intersect at the center of the flat plate portion.

(5) A plurality of the embedded portions are provided,
Each said embedding part is a guide wire in any one of said (2) thru | or (4) provided mutually spaced apart along the longitudinal direction of the said wire main body.

  (6) One flat plate forming portion of the first flat plate forming portion and the second flat plate forming portion has a protruding portion protruding in the thickness direction of the flat plate portion from the other flat plate forming portion. The guide wire according to any one of (1) to (5) above.

(7) One of the first flat plate forming portion and the second flat plate forming portion is made of stainless steel, and the other flat plate forming portion is made of a Ni—Ti alloy (1) The guide wire according to any one of (6) to (6).
(8) The boundary between the first flat plate forming portion and the second flat plate forming portion intersects with the central axis of the wire body in plan view of the flat plate portion. A guide wire according to any one of the above.
(9) The flat plate portion extends along the longitudinal direction of the wire body,
The guide line according to any one of (1) to (8), wherein a boundary line between the first flat plate forming portion and the second flat plate forming portion is inclined with respect to a longitudinal direction of the flat plate portion. Ya.

  ADVANTAGE OF THE INVENTION According to this invention, the guide wire which can shape the front-end | tip part of a guide wire to a desired shape easily and reliably, ensuring sufficient softness | flexibility at the front-end | tip part of a guide wire, and excellent in torque transmission property A wire can be provided.

FIG. 1 is a partial longitudinal sectional view (schematic side view) showing a first embodiment of the guide wire of the present invention. FIG. 2 is an enlarged detail view of a flat plate portion of the guide wire shown in FIG. FIG. 3 is a view for explaining a manufacturing process of the guide wire shown in FIG. FIG. 4 is a view for explaining a manufacturing process of the guide wire shown in FIG. FIG. 5 is a view for explaining a manufacturing process of the guide wire shown in FIG. FIG. 6 is a view for explaining the manufacturing process of the flat plate portion provided in the second embodiment of the guide wire of the present invention. FIG. 7 is a view for explaining the manufacturing process of the flat plate portion provided in the second embodiment of the guide wire of the present invention. FIG. 8 is a diagram for explaining a manufacturing process of a flat plate portion included in the second embodiment of the guide wire of the present invention. FIG. 9 is a plan view showing a flat plate portion provided in the third embodiment of the guide wire of the present invention. FIG. 10 is a plan view showing a flat plate portion provided in the fourth embodiment of the guide wire of the present invention. FIG. 11 is a plan view showing a flat plate portion provided in the fifth embodiment of the guide wire of the present invention. FIG. 12 is a plan view showing a flat plate portion provided in the sixth embodiment of the guide wire of the present invention. FIG. 13: is a top view which shows the flat plate part with which 7th Embodiment of the guide wire of this invention is provided. FIG. 14 is a perspective view showing a flat plate portion provided in the eighth embodiment of the guide wire of the present invention. FIG. 15: is a top view which shows the flat plate part with which 9th Embodiment of the guide wire of this invention is provided. FIG. 16: is a top view which shows the flat plate part with which 10th Embodiment of the guide wire of this invention is provided. FIG. 17 is a perspective view showing a flat plate portion provided in the eleventh embodiment of the guide wire of the present invention. FIG. 18 is a diagram for explaining a manufacturing process of the flat plate portion shown in FIG. FIG. 19 is a diagram for explaining a manufacturing process of the flat plate portion shown in FIG. FIG. 20 is a view for explaining a manufacturing process of the flat plate portion shown in FIG. FIG. 21 is a perspective view showing a flat plate portion provided in the twelfth embodiment of the guide wire of the present invention. FIG. 22 is an exploded perspective view showing a flat plate portion provided in the twelfth embodiment of the guide wire of the present invention. FIG. 23 is a plan view showing a flat plate portion provided in the thirteenth embodiment of the guide wire of the present invention. FIG. 24 is a plan view showing a flat plate portion provided in the fourteenth embodiment of the guide wire of the present invention. FIG. 25 is a plan view showing a flat plate portion provided in the fifteenth embodiment of the guide wire of the present invention. FIG. 26 is a plan view showing a flat plate portion provided in the sixteenth embodiment of the guide wire of the present invention. FIG. 27 is a plan view showing a flat plate portion provided in a seventeenth embodiment of the guide wire of the present invention. FIG. 28 is a plan view showing a flat plate portion provided in the eighteenth embodiment of the guide wire of the present invention.

Hereinafter, the hemostatic device of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.
<First Embodiment>
1 is a partial longitudinal sectional view showing a first embodiment of a guide wire according to the present invention (schematic side view, FIG. 2 is an enlarged detailed view of a flat plate portion of the guide wire shown in FIG. 1, and FIGS. It is a figure for demonstrating the manufacturing process of the guide wire shown in FIG.

  In the following, for convenience of explanation, the right side with respect to the longitudinal direction of the guide wire in FIGS. 1 to 4 is referred to as “base end”, the left side is referred to as “tip”, the upper side is “up”, and the lower side is “ Say "below". 1 to 5 (the same applies to FIGS. 6 to 28), in order to facilitate understanding, the length direction of the guide wire is shortened and the radial direction (thickness direction) of the guide wire is exaggerated. It is schematically shown, and the ratio between the length direction and the radial direction is different from the actual ratio.

  A guide wire 1 shown in FIG. 1 is a guide wire for a catheter that is used by being inserted into the lumen of a catheter (including an endoscope), and is disposed on the proximal end side of the first wire 2 and the first wire 2. A wire body 10 formed by joining the second wire 4 thus formed, the flat plate portion 3 provided on the distal end side of the first wire 2, and a spiral installed at the distal end portion (portion on the distal end side) of the wire body 10. Coil 5. The total length of the guide wire 1 is not particularly limited, but is preferably about 200 to 5000 mm.

  The first wire 2 is composed of a wire material having flexibility or elasticity. In the present embodiment, the first wire 2 has an outer diameter constant portion 21 whose outer diameter is substantially constant, and a first taper that is located on the distal side of the outer diameter constant portion 21 and whose outer diameter gradually decreases in the distal direction. A portion 22, a tip-side outer diameter constant portion 26 located on the tip side of the first taper portion 22, and a plate-like transition located further on the tip side, with a thickness decreasing toward the tip direction and a wider width A portion 27, a flat plate portion 3 located on the distal end side thereof, a large-diameter portion 24 located on the proximal end side with respect to the outer diameter constant portion 21 and having an outer diameter larger than that of the outer diameter constant portion 21, and an outer diameter constant portion 21 And a large diameter portion 24, and a second taper portion 23 whose outer diameter gradually decreases toward the tip. These are arranged in order of the transition portion 27, the distal end side outer diameter constant portion 26, the first taper portion 22, the outer diameter constant portion 21, the second taper portion 23, and the large diameter portion 24 from the distal end side of the first wire 2. ing.

  The first taper portion 22 is formed between the flat plate portion 3 and the constant outer diameter portion 21, and in particular, the flat plate portion 3 is formed in the vicinity of the distal end side of the first taper portion 22. The rigidity (bending rigidity, torsional rigidity) of the wire 2 can be gradually decreased toward the distal end direction. As a result, the guide wire 1 obtains good stenosis passage and flexibility at the distal end, The followability to the blood vessels and the safety are improved, and bending and the like can be prevented.

  Similarly to the first taper portion 22, the outer diameter constant portion 21 and the large diameter portion 24 are formed via the second taper portion 23, so that the rigidity (bending rigidity, torsional rigidity) of the first wire 2 is achieved. ) Can be gradually decreased toward the tip.

  Note that the taper angle (the reduction rate of the outer diameter) of the first taper portion 22 (the same applies to the second taper portion 23) is constant along the longitudinal direction of the wire body 10, but may vary along the longitudinal direction. May be. For example, a portion in which a taper angle (an outer diameter reduction rate) and a relatively small portion are alternately formed a plurality of times may be used.

  Further, the first taper portion 22 and the second taper portion 23 may have different taper shapes and taper angles.

  In the first wire 2, the outer diameter constant part 26, the outer diameter constant part 21, and the large diameter part 24 have constant outer diameters along the longitudinal direction of the wire. The outer diameter of the tip side outer diameter constant portion 26 is substantially equal to the minimum outer diameter of the first taper portion 22, and the outer diameter of the outer diameter constant portion 21 is substantially equal to the maximum outer diameter of the first taper portion 22. In addition, it is substantially equal to the minimum outer diameter of the second taper portion 23. The outer diameter of the large diameter portion 24 is substantially the same as the maximum outer diameter of the second tapered portion 23.

  A flat plate portion 3 configured as described below is preferably formed integrally with the first taper portion 22 on the tip end side of the first taper portion 22 via a tip end outer diameter constant portion 26 and a transition portion 27. ing. Here, the entire first wire 2 is integrally formed of the same material. As will be described later, a preferable constituent material of the first wire 2 is a superelastic alloy typified by a Ni—Ti alloy. (Alloy exhibiting pseudoelasticity). Therefore, a preferable constituent material of the flat plate portion 3 is also a superelastic alloy, and this case will be described below.

  As shown in FIG. 1, the flat plate portion 3 has a plate shape (ribbon shape), and can be used after being deformed into a desired shape (referred to as “reshape or shaping”). In general, in order to guide the distal end of a guide catheter or the like to a blood vessel shape, or to select and guide a blood vessel branch appropriately and smoothly, a doctor or the like previously sets the distal end of the guide wire to a desired shape. In this way, bending the tip of the guide wire into a desired shape is called reshaping. And by providing the flat plate part 3, reshaping can be performed easily and reliably, and the operativity at the time of inserting the guide wire 1 in a biological body improves markedly.

  In the present embodiment, the plate width of the flat plate portion 3 is substantially constant along the longitudinal direction. The value of the plate width of the flat plate portion 3 is not particularly limited as long as the flat plate portion 3 can be accommodated in the internal space (gap 50) of the coil 5, but in order to ensure sufficient flexibility and appropriate strength, The thickness is preferably about 0.05 to 0.3 mm, and more preferably about 0.15 to 0.25 mm.

  Moreover, in this embodiment, the plate | board thickness of the flat plate part 3 is substantially constant along the longitudinal direction. The value of the plate thickness of the flat plate portion 3 is not particularly limited, but is preferably about 0.01 to 0.06 mm and 0.02 to 0.04 mm in order to ensure sufficient flexibility and appropriate strength. More preferably, it is about.

  The distal end of the second wire 4 is joined to the proximal end of the first wire 2 (the proximal end of the large diameter portion 24). The second wire 4 is made of a flexible or elastic wire.

  The method for joining the first wire 2 and the second wire 4 is not particularly limited. For example, the joining is performed by welding such as friction welding, spot welding using a laser, butting resistance welding such as upset welding, or a tubular joining member. Although there is a method, butt resistance welding is particularly preferable because it is relatively simple and high joint strength can be obtained.

  In the present embodiment, the outer diameter of the second wire 4 is substantially constant. The outer diameter of the second wire 4 is substantially equal to the outer diameter of the large diameter portion 24 of the first wire 2. Thereby, when the base end of the large diameter part 24 of the 1st wire 2 and the front-end | tip of the 2nd wire 4 are joined, the outer diameter difference of both the wires 2 and 4 on the outer periphery of those joined parts (welded part) 6 A step is not generated, and a continuous surface can be formed. In addition, in this invention, the outer diameter of the 1st wire 2 and / or the 2nd wire 4 may change before and behind the junction part 6 not only in this.

  The average outer diameter of the first wire 2 is smaller than the average outer diameter of the second wire 4. As a result, the guide wire 1 is highly flexible on the first wire 2 on the distal end side and relatively high on the second wire 4 on the proximal end side. And excellent operability (pushability, torque transmission, etc.).

  The constituent materials of the first wire 2 and the second wire 4 are not particularly limited, and for example, stainless steel (for example, SUS304, SUS303, SUS316, SUS316L, SUS316J1, SUS316J1L, SUS405, SUS430, SUS434, SUS444, SUS429, Various metal materials such as SUS430F, all types of SUS such as SUS302), piano wires, cobalt-based alloys, alloys showing pseudoelasticity (including superelastic alloys) can be used.

  The constituent material of the first wire 2 is preferably an alloy (including a superelastic alloy) exhibiting pseudoelasticity, more preferably a superelastic alloy.

  Since the superelastic alloy is rich in flexibility, has a resilience, and is difficult to bend, the guide wire 1 is sufficiently flexible at the tip side by configuring the first wire 2 with the superelastic alloy. Performance and bendability, improved followability to complicatedly curved / bent blood vessels, etc., improved operability, and even if the first wire 2 repeatedly bends / bends, Since the bend crease is not attached due to the resilience of the 1 wire 2, it is possible to prevent the operability from being lowered due to the bend crease on the first wire 2 during use of the guide wire 1.

  Pseudoelastic alloys include any shape of stress-strain curve due to tension, including those that can measure the transformation point of As, Af, Ms, Mf, etc., and those that cannot be measured. However, everything that returns to its original shape by removing stress is included.

  The preferred composition of the superelastic alloy is Ni-Ti alloy such as Ni-Ti alloy of 49-52 atomic% Ni, Cu-Zn alloy of 38.5-41.5 wt% Zn, 1-10 wt% X Cu-Zn-X alloy (X is at least one of Be, Si, Sn, Al, and Ga), 36-38 atomic% Al-Ni-Al alloy, and the like. Of these, the Ni-Ti alloy is particularly preferable. In addition, the superelastic alloy represented by Ni-Ti type alloy is excellent also in the adhesiveness of the resin coating layer 8 mentioned later.

  The cobalt-based alloy has a high elastic modulus when used as a wire and has an appropriate elastic limit. For this reason, the wire comprised by the cobalt type alloy is excellent in torque transferability, and problems, such as buckling, do not arise very much. Any cobalt-based alloy may be used as long as it contains Co as a constituent element, but it contains Co as a main component (Co-based alloy: Co content in the elements constituting the alloy) Is preferable, and a Co—Ni—Cr alloy is more preferably used. By using an alloy having such a composition, the above-described effects become more remarkable. In addition, an alloy having such a composition has a high elastic modulus and can be cold-formed even as a high elastic limit, and by reducing the diameter while sufficiently preventing buckling from occurring due to the high elastic limit. And can have sufficient flexibility and rigidity to be inserted into a predetermined portion.

  The constituent material of the second wire 4 is preferably the above-described stainless steel. Stainless steel has higher strength and rigidity than the superelastic alloy, and therefore can impart excellent pushability and torque transmission to the guide wire 1.

  The first wire 2 and the second wire 4 may be made of different materials, but may be made of the same or the same kind of metal material (the same main metal material in the alloy is equal). In the latter case, the joint strength of the joint portion (welded portion) 6 becomes higher, and even if the outer diameter of the joint portion 6 is small, excellent torque transmission properties and the like are exhibited without causing separation or the like.

  When the first wire 2 and the second wire 4 are made of different materials, the first wire 2 is preferably made of the superelastic alloy described above, and particularly made of a Ni—Ti alloy. The second wire 4 is preferably made of the above-described stainless steel.

  In the above description, the first wire 2 and the second wire 4 are joined. However, the first wire 2 and the second wire 4 may be composed of a single continuous wire body without a joint. In this case, examples of the constituent material of the wire body include the same materials as described above, and stainless steel, cobalt-based alloys, and pseudoelastic alloys are particularly preferable.

  A coil 5 is arranged on the outer periphery of the distal end portion of the wire body 10 so as to cover the distal end portion together with the flat plate portion 3. The installation of the coil 5 reduces the contact area of the surface of the wire body 10 with the inner wall of the catheter and the surface of the living body, thereby reducing the sliding resistance. As a result, the operability of the guide wire 1 is further improved. improves.

  As shown in FIG. 1, a wire main body 10 is inserted through the central portion inside the coil 5. In the case of the present embodiment, the flat plate portion 3, the transition portion 27, the distal end side outer diameter constant portion 26, the first taper portion 22, and all or part of the outer diameter constant portion 21 are covered with the coil 5. ing.

  Further, the distal end portion of the wire body 10 (particularly, the region from the flat plate portion 3 to the first tapered portion 22) is inserted in a non-contact manner with the inner surface of the coil 5. As a result, a gap 50 is formed between the coil 5 and the tip of the wire body 10.

  The coil 5 is formed by spirally forming a strand 54 having a circular cross section. In this case, one strand 54 may be spirally wound, or a plurality of strands 54 may be spirally wound.

  The constituent material of the strand 54 is not specifically limited, Any of a metal material and a resin material may be sufficient. Preferable examples of the metal material include X-ray opaque materials such as stainless steel, noble metals such as Au and Pt, and alloys containing the noble metals (for example, Pt—Ni alloys). In the latter case, X-ray contrast property is obtained at the distal end portion of the guide wire 1, and it can be inserted into the living body while confirming the position of the distal end portion under X-ray fluoroscopy, which is preferable.

  The coil 5 may be a combination of two or more materials. For example, the strand 54 on the distal end side of the coil 5 can be made of an X-ray opaque material such as the Pt—Ni alloy, and the strand 54 on the proximal end side of the coil 5 can be made of stainless steel. In this case, under X-ray fluoroscopy, it is possible to emphasize a portion (particularly, a portion including the flat plate portion 3) located on the distal end side of the coil 5 more than a portion located closer to the proximal end ( Therefore, the position of the most distal portion (the portion where the flat plate portion 3 is present) of the guide wire 1 can be visually recognized more clearly.

  Further, as shown in the figure, the flat plate portion 3, the transition portion 27, the distal end side outer diameter constant portion 26, the first taper portion are not limited to the case where the portion from the flat plate portion 3 to the constant outer diameter portion 21 is covered with the coil 5. 22 and a part of the constant outer diameter portion 21 may be covered with the coil 5. In this case, it is preferable that at least the outer periphery of the flat plate portion 3 is covered with the coil 5.

  Further, when the coil 5 is installed on the outer periphery of the flat plate portion 3, the coil 5 may be in contact with or in close contact with the flat plate portion 3, and such a coil 5 is used as the flat plate portion 3 of the guide wire 1. It may be installed for the purpose of imparting X-ray contrast properties to the site where there is.

  The wire diameter of the wire 54 of the coil 5 may be the same over the entire length of the coil 5, but the wire diameter of the wire 54 may be different between the distal end side and the proximal end side of the coil 5. For example, the wire diameter of the strand 54 may be smaller (or larger) on the distal end side of the coil 5 than on the proximal end side. Thereby, the softness | flexibility of the guide wire 1 in the front-end | tip part of the coil 5 can be improved more.

  The outer diameter of the coil 5 may be the same over the entire length of the coil 5, but the outer diameter of the coil 5 may be different between the distal end side and the proximal end side of the coil 5. For example, the outer diameter of the coil 5 may be smaller on the distal end side of the coil 5 than on the proximal end side. Thereby, the softness | flexibility of the guide wire 1 in the front-end | tip part of the coil 5 can be improved more.

  In this embodiment, the adjacent strands 54 of the coil 5 are in contact with each other and are in a so-called densely wound state. These strands 54 generate a force (compression force) that pushes each other in the axial direction of the wire body 10 in a natural state. Here, the “natural state” refers to a state where no external force is applied. However, the present invention is not limited to this, and there may be a place where the adjacent strands 54 of the coil 5 are separated from each other.

  As shown in FIG. 1, the coil 5 is fixed to the wire body 10 at two places (a plurality of places). That is, the distal end portion of the coil 5 is fixed to the distal end of the first wire 2 (the distal end of the flat plate portion 3) by the fixing material 51, and the proximal end portion of the coil 5 is in the middle of the first wire 2 by the fixing material 53 (constant outer diameter). Near the boundary between the portion 21 and the second taper portion 23). By fixing at such a location, the respective portions of the coil 5 can be reliably fixed to the wire body 10 without impairing the flexibility of the distal end portion (the portion where the coil 5 is present) of the guide wire 1. . Moreover, the flat plate part 3 can be reliably fixed with respect to the coil 5, and the shape of the shaped flat plate part 3 can be hold | maintained appropriately.

  Each of the fixing materials 51 and 53 is preferably made of solder (brazing material). The fixing materials 51 and 53 are not limited to solder and may be adhesives. Further, the method for fixing the coil 5 to the wire body 10 is not limited to the above-described fixing material, and for example, welding may be used. Moreover, in order to prevent damage to the inner wall of a body cavity such as a blood vessel, the distal end surface of the fixing material 51 is preferably rounded (see FIG. 1).

  As shown in FIG. 1, a resin coating layer 8 is provided on the outer surface of the guide wire 1 so as to cover the whole (or a part thereof). The resin coating layer 8 can be formed for various purposes. As an example, the operability of the guide wire 1 is reduced by reducing the friction (sliding resistance) of the guide wire 1 and improving the slidability. May be improved.

  In order to reduce the friction (sliding resistance) of the guide wire 1, the resin coating layer 8 is preferably made of a material that can reduce friction as described below. Thereby, the frictional resistance (sliding resistance) with the inner wall of the catheter used together with the guide wire 1 is reduced, the slidability is improved, and the operability of the guide wire 1 in the catheter becomes better. Further, since the sliding resistance of the guide wire 1 is reduced, when the guide wire 1 is moved and / or rotated in the catheter, kinks (bending) or twisting of the guide wire 1, Twist can be prevented more reliably.

  Examples of materials that can reduce such friction include polyolefins such as polyethylene and polypropylene, polyvinyl chloride, polyesters (PET, PBT, etc.), polyamides, polyimides, polyurethanes, polystyrenes, polycarbonates, silicone resins, fluorine resins ( PTFE, ETFE, etc.) or a composite material thereof.

  The resin coating layer 8 can also be provided for the purpose of improving safety when the guide wire 1 is inserted into a blood vessel or the like. For this purpose, it is preferable that the resin coating layer 8 is made of a flexible material (soft material, elastic material).

  Examples of such flexible materials include polyolefins such as polyethylene and polypropylene, polyvinyl chloride, polyester (PET, PBT, etc.), polyamide, polyimide, polyurethane, polystyrene, silicone resin, polyurethane elastomer, polyester elastomer, polyamide. Examples thereof include thermoplastic elastomers such as elastomers, various rubber materials such as latex rubber and silicone rubber, or composite materials in which two or more thereof are combined.

  In addition, the resin coating layer 8 is not limited to being entirely made of the same material, and the constituent material may be different in the middle of the guide wire 1 in the longitudinal direction. For example, the material of the portion covering the first wire 2 and the coil 5 of the resin coating layer 8 is made of the flexible material, and the material of the portion covering the second wire 4 of the resin coating layer 8 is the friction. The material can be reduced.

  The resin coating layer 8 may be a single layer or a laminate of two or more layers (for example, an inner layer made of a material that is more flexible than an outer layer). For example, the portion of the resin coating layer 8 that covers the first wire 2 and the coil 5 can be a single layer, and the material of the portion of the resin coating layer 8 that covers the second wire 4 can be a laminate of two or more layers. . Moreover, the reverse may be sufficient.

  Grooves (not shown) may be formed on the outer peripheral surface of the resin coating layer 8. In particular, at least a portion of the resin coating layer 8 corresponding to the flat plate portion 3 (outer peripheral portion of the flat plate portion 3) is formed with a groove having a pattern such as a linear shape, a curved shape, a ring shape, a spiral shape, or a net shape. Is preferred. By forming such a groove, the flexibility of the distal end portion of the guide wire 1 is increased, the friction (sliding resistance) of the guide wire 1 is reduced, and the slidability can be further improved.

  Further, it is preferable that a hydrophilic material is coated on at least the outer surface of the guide wire 1. As a result, the hydrophilic material is wetted to produce lubricity, the friction (sliding resistance) of the guide wire 1 is reduced, and the slidability is improved. Therefore, the operability of the guide wire 1 is improved.

  Examples of hydrophilic materials include cellulose-based polymer materials, polyethylene oxide-based polymer materials, and maleic anhydride-based polymer materials (for example, maleic anhydride copolymers such as methyl vinyl ether-maleic anhydride copolymer). Acrylamide polymer substances (for example, polyacrylamide, polyglycidyl methacrylate-dimethylacrylamide (PGMA-DMAA) block copolymer), water-soluble nylon, polyvinyl alcohol, polyvinylpyrrolidone and the like.

  In many cases, such a hydrophilic material exhibits lubricity by wetting (water absorption) and reduces frictional resistance (sliding resistance) with the inner wall of the catheter used together with the guide wire 1. Thereby, the slidability of the guide wire 1 is improved, and the operability of the guide wire 1 in the catheter becomes better.

  As shown in FIGS. 1 and 2, the flat plate portion 3 includes a pair of flexible portions (first flat plate forming portions) 31 rich in flexibility and a rigid portion (first plate) having higher rigidity than each flexible portion 31. 2 flat plate forming portions) 32. The rigid portion 32 functions as a reinforcing portion that reinforces the flat plate portion 3.

  Each flexible portion 31 is rectangular in plan view of the flat plate portion 3 and is separated in the longitudinal direction of the wire body 10. The flexible portion 31 on the proximal end side is formed integrally with the first wire 2.

  The rigid portion 32 is provided between the flexible portions 31 and is embedded in the flat plate portion 3. The rigid portion 32 extends in a direction orthogonal to the longitudinal direction of the wire body 10, that is, in the width direction of the flat plate portion 3.

  As shown in FIG. 2, the rigid portion 32 is provided over the entire width direction of the flat plate portion 3. Thereby, in the middle of the longitudinal direction of the flat plate part 3, the rigidity of the flat plate part 3 can be improved uniformly over the entire region in the width direction. The rigid portion 32 is provided over the entire area of the flat plate portion 3 in the thickness direction. Thereby, in the middle of the longitudinal direction of the flat plate part 3, the rigidity of the flat plate part 3 can be improved uniformly over the entire region in the thickness direction.

  When torque about the axis (hereinafter simply referred to as “torque”) is applied to the proximal end portion of the guide wire 1, the distal end of the guide wire 1 in the order of the second wire 4, the first wire 2, and the flat plate portion 3 from the proximal end side. Torque is transmitted toward the side. Since the flat plate portion 3 is flexible, that is, a portion that is easily elastically deformed (easy to twist), there is a fear that torque transmission may be insufficient, but the flat plate portion 3 is provided with a rigid portion 32. Thereby, it can suppress or prevent that transmission of torque becomes inadequate in the flat plate part 3.

  Thus, since the flat plate part 3 has the flexible part 31 and the rigid part 32, sufficient torque transmission property can also be ensured, maintaining a high softness | flexibility. That is, in the guide wire 1, it is possible to achieve both contradictory characteristics of flexibility and torque transmission.

  Here, since the guide wire 1 is used by being inserted into a living body, the distal end portion, particularly the flat plate portion 3 is required to be thin (thinned). In the guide wire 1, as described above, the rigid portion 32 is an embedded portion embedded in the flat plate portion 3. Thereby, compared with the case where the rigid part is provided separately on the surface of the plate-like flexible part, the thickness of the flat plate part 3 can be reduced by the amount of the rigid part 32 embedded therein. Accordingly, both the reinforcement of the flat plate portion 3 and the thinning can be achieved.

  Furthermore, as shown in FIG. 2, the thickness of the flexible part 31 and the rigid part 32 is equal. For this reason, the thickness of the flat plate portion 3 is constant over the entire length of the wire body 10 in the longitudinal direction. Thereby, it can prevent that a level | step difference part is formed in both surfaces of the flat plate part 3. FIG. Therefore, when the flat plate portion 3 is deformed, the stepped portion can be reliably prevented from being caught by the wire 54 of the coil 5.

  The ratio of the length of the flexible portion 31 (the sum of the lengths of the flexible portions 31) and the length of the rigid portion 32 in the longitudinal direction of the flat plate portion 3 is 0.2: 0.8 to 0.8: 0. .2 is preferable, and about 0.4: 0.6 to 0.6: 0.4 is more preferable. Thereby, the softness | flexibility and torque transmission property of the flat plate part 3 can be improved without excess and deficiency.

  In addition, the flexible part 31 can be comprised with the same material (1st material) as the 1st wire 2, and it is especially preferable that it is comprised with the Ni-Ti type alloy especially. On the other hand, the rigid portion 32 can be made of the same material (second material) as that of the second wire 4, and is particularly preferably made of stainless steel.

  By forming the flexible portion 31 with a Ni—Ti alloy and the rigid portion 32 with stainless steel, there is an advantage in the manufacturing method of the flat plate portion 3 described below.

Next, the manufacturing method of the guide wire 1 (flat plate part 3) is demonstrated. It should be noted that a known technique can be used for a method for manufacturing a portion of the guide wire 1 other than the flat plate portion 3. Therefore, below, the manufacturing method of the flat plate part 3 is demonstrated.
The manufacturing method of the flat plate part 3 includes a preparation process, a joining process, and a pressing process.

[1] Preparation Step First, as shown in FIG. 3, a first base material 100, a second base material 320, and a third base material 310 are prepared.

  The first base material 100 is a base material that becomes the first wire 2 (flexible portion 31). The second base material 320 is a base material that becomes the rigid portion 32. The third base material 310 is a base material that becomes the flexible portion 31. The first base material 100, the second base material 320, and the third base material 310 each have a columnar shape with the same diameter.

[2] Joining Step The third base material 310, the second base material 320, and the first base material 100 are arranged concentrically in order from the tip side. And as shown in FIG. 4, while joining the base end surface of the 3rd base material 310, and the front end surface of the 2nd base material 320, the base end surface of the 2nd base material 320, and the front end surface of the 1st base material 100, Join. Thereby, the 3rd preform | base_material 310, the 2nd preform | base_material 320, and the 1st preform | base_material 100 become the one linear joined body 200. FIG.

  As these joining methods, butt resistance welding is preferable. By configuring the third base material 310 with a Ni—Ti alloy and the second base material 320 with stainless steel, the third base material 310 can be easily and reliably joined by butt resistance welding.

[3] Pressing process Then, press molding is performed on the portion of the joined body 200 that becomes the flat plate portion 3. At this time, pressure is applied from the direction orthogonal to the central axis of the joined body 200, that is, the vertical direction in FIG. Thereby, the 3rd base material 310, the 2nd base material 320, and the 1st base material 100 are crushed with joining, respectively, and become the plate shape shown in Drawing 5, Therefore, flat plate part 3 can be obtained. it can.

  According to such a manufacturing method of the flat plate portion 3, the flat plate portion 3 can be obtained by a simple method of bonding the base materials and pressing the bonded body 200.

Second Embodiment
FIGS. 6-8 is a figure for demonstrating the manufacturing process of the flat plate part with which 2nd Embodiment of the guide wire of this invention is provided.

  Hereinafter, the second embodiment of the guide wire of the present invention will be described with reference to these drawings, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the said 1st Embodiment except the structures (shapes of a base material) of a flat plate part differing.

  As shown in FIG. 8, in the flat plate portion 3A, the flexible portion 31 is disposed on the distal end side, and the rigid portion 32 is disposed on the proximal end side. Further, the boundary line 300 between the flexible portion 31 and the rigid portion 32 is inclined with respect to the longitudinal direction of the flat plate portion 3A. For this reason, the flat plate portion 3A has a configuration in which the rigidity gradually decreases toward the tip side. That is, in the longitudinal direction of the flat plate portion 3A, the region having the boundary line 300 is a physical property transition portion where the physical properties gradually transition. When the flat plate portion is bent, the stress tends to concentrate on the portion where the rigidity changes sharply, and it is easy to bend. However, in the flat plate portion 3A, the rigidity gradually decreases toward the tip side, so that stress is applied to the portion. Concentration can be prevented. Therefore, it is possible to prevent the bending that starts from the portion caused by the concentration of stress on the portion.

Next, the manufacturing method of 3 A of flat plate parts is demonstrated.
[1] Preparation Step First, as shown in FIG. 3, a fourth base material 310 </ b> A that becomes the flexible portion 31 and a fifth base material 100 </ b> A that becomes the rigid portion 32 are prepared.

  The fourth base material 310A has a cylindrical shape, and the base end surface 311A is inclined with respect to the central axis. In the fifth base material 100A, the tip surface 101A is inclined with respect to the central axis. The inclination angle of the base end face 311A and the inclination angle of the tip end face 101A are the same.

[2] Joining Step Next, the fourth base material 310A and the fifth base material 100A are arranged concentrically. Then, the base end surface 311A and the distal end surface 101A are joined so that the fourth base material 310A and the fifth base material 100A become one linear joined body 200A.

[3] Pressing step Then, press forming is performed on the portion to be the flat plate portion 3A. Thereby, 3 A of flat plate parts can be obtained.

<Third Embodiment>
FIG. 9 is a plan view showing a flat plate portion provided in the third embodiment of the guide wire of the present invention.

  Hereinafter, the third embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the said 1st Embodiment except the structures of a flat plate part differing.

  As shown in FIG. 9, in the flat plate portion 3B, a pair of flexible portions 31 and rigid portions 32 are provided. Further, in the flat plate portion 3B, the flexible portion 31, the rigid portion 32, the flexible portion 31, the rigid portion 32, and the flexible portion 31 are provided alternately in the longitudinal direction of the flat plate portion 3B from the front end side.

  According to such a structure, in the flat plate part 3B, it can be increased more than the boundary part of the flexible part 31 and the rigid part 32, and 1st Embodiment. As a result, the stress concentrated on each boundary portion is dispersed as the number of boundary portions (boundary lines) 500 increases. Therefore, a sharp bend at the boundary can be more effectively prevented. Further, when the flat plate portion 3B is bent in the thickness direction, the amount of the boundary portion 500 can be bent gently.

<Fourth embodiment>
FIG. 10 is a plan view showing a flat plate portion provided in the fourth embodiment of the guide wire of the present invention.

  Hereinafter, the guide wire according to the fourth embodiment of the present invention will be described with reference to the drawings. However, the difference from the above-described embodiment will be mainly described, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the said 3rd Embodiment except the structures of a flat plate part differing.

  As shown in FIG. 10, in the flat plate portion 3C, each rigid portion 32 is provided inclined with respect to the longitudinal direction of the flat plate portion 3C. Thereby, since each rigid part 32 inclines, the part reinforced by each rigid part 32 in the longitudinal direction of 3 C of flat plate parts can be increased.

  Moreover, according to such a structure, 3 C of flat plate parts can be made easy to bend in the arrow C direction in FIG. That is, the flat plate portion 3C has an effective configuration when it is desired to bend it in the direction of arrow C in FIG.

<Fifth Embodiment>
FIG. 11 is a plan view showing a flat plate portion provided in the fifth embodiment of the guide wire of the present invention.

  Hereinafter, the fifth embodiment of the guide wire of the present invention will be described with reference to this drawing. However, the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the said 1st Embodiment except the structures of a flat plate part differing.

  As shown in FIG. 11, in the flat plate portion 3D, the rigid portion 32 is provided to be inclined. Thereby, since the rigid portion 32 is inclined, the portion reinforced by the rigid portion 32 in the longitudinal direction of the flat plate portion 3 can be increased.

  Further, according to such a configuration, the flat plate portion 3D can be easily bent in the arrow D direction in FIG. That is, the flat plate portion 3D has an effective configuration when it is desired to bend it in the direction of arrow D in FIG.

<Sixth Embodiment>
FIG. 12 is a plan view showing a flat plate portion provided in the sixth embodiment of the guide wire of the present invention.

  Hereinafter, the sixth embodiment of the guide wire according to the present invention will be described with reference to this figure. However, the difference from the above-described embodiment will be mainly described, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the said 1st Embodiment except the structures of a flat plate part differing.

  As shown in FIG. 12, in the flat plate portion 3E, the positional relationship (arrangement) between the rigid portion 32 of the flat plate portion 3 of the first embodiment and the flexible portions 31 and 32 is reversed. That is, in the flat plate portion 3E, the rigid portion 32, the flexible portion 31, and the rigid portion 32 are arranged in this order from the distal end side.

  Thus, in this embodiment, it has the structure by which the flexible part 31 was embed | buried in the flat plate part 3E.

  Further, the transition portion 27 and the distal end side constant outer diameter portion 26 are also rigid portions 32. The transition portion 27 and the distal end side outer diameter constant portion 26 are relatively thin portions of the wire body 10. By using the relatively thin portion as the rigid portion 32, it is possible to further improve the torque transmission performance of the wire body 10 as a whole.

<Seventh embodiment>
FIG. 13: is a top view which shows the flat plate part with which 7th Embodiment of the guide wire of this invention is provided.

  Hereinafter, the seventh embodiment of the guide wire of the present invention will be described with reference to this drawing. However, the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the sixth embodiment except that the configuration of the flat plate portion is different.

  As shown in FIG. 13, in the flat plate portion 3F, the flexible portion 31 is inclined with respect to the flat plate portion 3F. Thereby, the part which was rich in the softness | flexibility in the longitudinal direction of the flat plate part 3F can be increased because the flexible part 31 inclines.

  Also in this embodiment, the flat plate portion 3F can be easily bent in the direction of arrow E in FIG. That is, the flat plate portion 3F is effective when it is desired to bend in the direction of arrow E in FIG.

<Eighth Embodiment>
FIG. 14 is a perspective view showing a flat plate portion provided in the eighth embodiment of the guide wire of the present invention.

  Hereinafter, the eighth embodiment of the guide wire according to the present invention will be described with reference to this drawing. However, the difference from the above-described embodiment will be mainly described, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the said 1st Embodiment except the structures of a flat plate part differing.

  As shown in FIG. 14, the flat plate portion 3 </ b> G includes a rigid portion 32 and a plate-like flexible portion 31. The flexible portion 31 is formed with a groove 311 that opens to the upper surface 35 in FIG. 14 of the flat plate portion 3G. The groove 311 is provided along the diagonal line of the flexible portion 31. A rigid portion 32 is inserted into the groove 311.

  Thus, in the flat plate portion 3G, the rigid portion 32 is embedded to the middle in the thickness direction of the flat plate portion 3G. Thereby, the surface 35 side of the flat plate portion 3G can be reinforced intensively. Further, a groove can be formed on the surface 36 opposite to the surface 35, and a rigid portion can be inserted in accordance with the shape of the groove. In addition, the groove formed on the surface 36 may have a shape different from the groove 311 on the surface 35. Therefore, the degree of freedom in design can be improved.

  Further, since the rigid portion 32 is provided on the diagonal line of the flexible portion 31, the entire region in the longitudinal direction of the flat plate portion 3G is reinforced by the rigid portion 32. Thereby, pushability is also improved.

  In addition, it does not specifically limit as a manufacturing method of the flat plate part 3G, The method of forming the groove | channel 311 in the flexible part 31 previously and inserting the rigid part 32 in the groove | channel 311 may be used. In this case, the inner surface of the groove 311 and the outer surface of the rigid portion 32 are fixed.

  In addition to the above manufacturing method, for example, a linear rigid portion 32 may be arranged on the surface of the flexible portion 31 where no groove is formed, and press working may be performed in this arrangement state. In this case, the flexible portion 31 can be deformed so as to follow the shape of the rigid portion 32 by being pressed by the rigid portion 32 in the press working. Therefore, the rigid portion 32 is embedded in the flexible portion 31 as shown in FIG.

<Ninth Embodiment>
FIG. 15: is a top view which shows the flat plate part with which 9th Embodiment of the guide wire of this invention is provided.

  Hereinafter, the ninth embodiment of the guide wire of the present invention will be described with reference to this drawing. However, the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of the present embodiment is the same as that of the eighth embodiment except that the configuration of the flat plate portion is different.

  As shown in FIG. 15, in the flat plate portion 3H, two grooves 311 are provided. Each groove 311 is provided along two diagonal lines different from each other, and each groove 311 communicates with a central portion in plan view of the flat plate portion 3G. In such a groove 311, an “X” -shaped groove is inserted.

  According to such a structure, the center part in planar view of the flat plate part 3H can be reinforced intensively. Moreover, it can be set as a symmetrical shape via a central axis in planar view of the flat plate part 3H, Therefore Even if it bends the flat plate part 3H in any direction, it can be set as the same bendability.

<Tenth Embodiment>
FIG. 16: is a top view which shows the flat plate part with which 10th Embodiment of the guide wire of this invention is provided.

  Hereinafter, a tenth embodiment of the guide wire of the present invention will be described with reference to this drawing. However, the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of the present embodiment is the same as that of the ninth embodiment except that the configuration of the flat plate portion is different.

  As shown in FIG. 16, in the flat plate portion 3J, the rigid portion 32 extends along the longitudinal direction of the flat plate portion 3J so as to pass through the central portion of the flat plate portion 3J. Thereby, flat plate part 3J can be reinforced along the longitudinal direction. Therefore, the guide wire of this embodiment is particularly excellent in pushability.

<Eleventh embodiment>
FIG. 17 is a plan view showing a flat plate portion provided in the eleventh embodiment of the guide wire of the present invention, and FIGS. 18 to 20 are diagrams for explaining the manufacturing process of the flat plate portion shown in FIG.

  Hereinafter, the eleventh embodiment of the guide wire according to the present invention will be described with reference to these drawings. However, the difference from the above-described embodiment will be mainly described, and the description of the same matters will be omitted.

  The guide wire of the present embodiment is the same as that of the eighth embodiment except that the configuration of the flat plate portion is different.

  As shown in FIGS. 17 and 18, in the flat plate portion 3 </ b> K, the groove 311 passes through the central portion of the flexible portion 31 from the surface 35 to the surface 36. The groove 311 is provided to be inclined with respect to the longitudinal direction of the flat plate portion 3. In the present embodiment, one end of the groove 311 is located closer to the central portion of the flat plate portion 3K than the side surface 37 of the flat plate portion 3K, and the other end is the central portion of the flat plate portion 3K from the side surface 38 of the flat plate portion 3K. Located on the side.

  The rigid portion 32 is inserted into the groove 311 and has an embedded portion 321 embedded in the flexible portion 31 and a pair of protruding portions 322 protruding in the thickness direction of the flat plate portion 3K from the flexible portion 31. doing.

  Each protrusion 322 has a plate shape and is provided so as to sandwich the flexible portion 31 in the thickness direction of the flat plate portion 3K. Each protrusion 322 sufficiently includes the groove 311 in a plan view. Thereby, the rigid part 32 is fixed to the flexible part 31.

  Moreover, as shown in FIG. 17, the rigid part 32 is provided in the middle of the width direction of the flat plate part 3K. That is, one end of the rigid portion 32 is located closer to the central portion of the flat plate portion 3K than the side surface 37 of the flat plate portion 3K, and the other end is located closer to the central portion of the flat plate portion 3K than the side surface 38 of the flat plate portion 3K. Yes. Thereby, the central part vicinity of the flat plate part 3K in planar view of the flat plate part 3K can be reinforced intensively.

Next, a manufacturing method of the flat plate portion 3G will be described.
[1] Preparation Step First, as shown in FIG. 18, the flexible portion 31 in which the groove 311 is formed and the sixth base material 320 </ b> B are prepared. The sixth base material 320 </ b> B has the above-described protrusion 322 and a protrusion 322 ′ protruding from the protrusion 322. Then, as shown in FIG. 19, the convex portion 322 ′ is inserted into the groove 311. In the inserted state, the convex portion 322 ′ protrudes from the groove 311 at the top.

[2] Pressing Step Next, as shown in FIG. 20, press molding is performed so as to apply pressure in the thickness direction of the flexible portion 31. At this time, it presses until the top part of convex part 322 'deform | transforms into plate shape. Thereby, the top part of convex part 322 'becomes the protrusion part 322. FIG. Therefore, the flexible part 31 is fixed by the pair of projecting parts 322. At this time, the portion of the convex portion 322 ′ inserted into the groove 311 becomes the embedded portion 321.

  Thus, in this embodiment, since the rigid part 32 and the flexible part 31 are fixed by caulking, a joining process can be skipped. Therefore, the flat plate portion 3K can be obtained more easily. Furthermore, since the flexible portion 31 is sandwiched between the pair of projecting portions 322, it is possible to reliably prevent the rigid portion from being detached from the flexible portion 31 during the operation of the guide wire.

<Twelfth embodiment>
FIG. 21 is a perspective view showing a flat plate portion provided in the eleventh embodiment of the guide wire of the present invention, and FIG. 22 is an exploded perspective view of the guide wire shown in FIG.

  Hereinafter, the eleventh embodiment of the guide wire according to the present invention will be described with reference to these drawings. However, the difference from the above-described embodiment will be mainly described, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the said 1st Embodiment except the structures of a flat plate part differing.

  As shown in FIGS. 21 and 22, in the flat plate portion 3 </ b> L, the entire surface of the flexible portion 31 is covered with the rigid portion 32. That is, the flexible part 31 is embedded in the rigid part 32.

  The rigid portion 32 has a plate shape and is formed with a recess 323 that opens to the base end surface. By inserting the flexible portion 31 into the recess 323, the flat plate portion 3L can be obtained. Further, the rigid portion 32 and the flexible portion 31 may be fixed by, for example, adhesion or fusion (thermal fusion, ultrasonic fusion, etc.) using an adhesive in addition to the pressure bonding described in the above embodiment.

  According to such this embodiment, it can reinforce over the whole area of the longitudinal direction of the flat plate part 3L, the width direction, and the thickness direction.

<13th Embodiment>
FIG. 23 is a plan view showing a flat plate portion provided in the thirteenth embodiment of the guide wire of the present invention.

  Hereinafter, the thirteenth embodiment of the guide wire according to the present invention will be described with reference to this figure. However, the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of this embodiment is the same as that of the twelfth embodiment except that the configuration of the rigid portion is different.

  As shown in FIG. 23, in the flat plate portion 3M, the length of the rigid portion 32 is shorter than the rigid portion 32 in the twelfth embodiment. Thereby, the base end part of the flexible part 31 is exposed. Thereby, the exposed part of the flexible part 31 is rich in flexibility.

  Thus, by adjusting the length of the rigid portion 32, the degree of reinforcement of the flat plate portion 3M can be easily adjusted.

<Fourteenth embodiment>
FIG. 24 is a plan view showing a flat plate portion provided in the fourteenth embodiment of the guide wire of the present invention.

  Hereinafter, the fourteenth embodiment of the guide wire according to the present invention will be described with reference to this figure. However, the difference from the above-described embodiment will be mainly described, and the description of the same matters will be omitted.

  The guide wire of the present embodiment is the same as that of the thirteenth embodiment except that the configuration of the rigid portion is different.

  As shown in FIG. 24, in the flat plate portion 3Q, the length of the rigid portion 32 is shorter than the rigid portion of the thirteenth embodiment. Moreover, the recessed part 323 has penetrated from the front-end | tip to the base end. Thereby, the flexible part 31 can penetrate the rigid part 32.

  According to such a configuration, the portion to be reinforced can be easily adjusted by adjusting the position of the rigid portion 32 in the longitudinal direction of the flexible portion 31. For example, as shown in the drawing, the flexible portion 31 is inserted through the rigid portion 32 halfway in the longitudinal direction, and the distal end portion of the flexible portion 31 is exposed, so that the distal end portion of the flat plate portion 3Q is rich in flexibility.

<Fifteenth embodiment>
FIG. 25 is a plan view showing a flat plate portion provided in the fifteenth embodiment of the guide wire of the present invention.

  Hereinafter, the fifteenth embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of this embodiment is substantially the same as the twelfth embodiment except that the configuration of the rigid portion is different.

  As shown in FIG. 25, in the flat plate portion 3 </ b> R, the rigid portion 32 is configured such that the portion covering the surface 35 and the surface 36 of the flexible portion 31 has two wire rods 324 intersecting at the central portion of the rigid portion 32. It has become. Thereby, compared with the case where the rigid part 32 has covered the whole surface 35 and the surface 36 of the flexible part 31 like 12th Embodiment, it can make the flat plate part 3R rich in a softness | flexibility. Furthermore, the flat plate portion 3R is easily bent in the thickness direction.

  In addition, the rigid part 32 can be made into mesh shape by increasing the number of the wire 324. FIG.

<Sixteenth Embodiment>
FIG. 26 is a plan view showing a flat plate portion provided in the sixteenth embodiment of the guide wire of the present invention.

  Hereinafter, the sixteenth embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of the present embodiment is substantially the same as the fifteenth embodiment except that the configuration of the rigid portion is different.

  As shown in FIG. 26, in the flat plate portion 3S, one of the two wires 324 of the rigid portion of the fifteenth embodiment is omitted from the rigid portion 32. For this reason, the flat plate portion 3S is more flexible than the flat plate portion 3R of the fifteenth embodiment.

  Further, the wire 324 on the surface 36 side of the rigid portion 32 has the same inclination direction as the wire 324 on the surface 35 side. Accordingly, the wire 324 on the surface 35 side and the wire 324 on the surface 36 side overlap each other in plan view of the flat plate portion 3S. Thereby, the flat plate part 3S can be easily bent in the direction of arrow F in FIG.

  In addition, when the wire 324 on the surface 35 side and the wire 324 on the surface 36 side overlap in a plan view of the flat plate portion 3H, it is possible to bend the flat plate portion 3H in almost any direction easily.

<Seventeenth Embodiment>
FIG. 27 is a plan view showing a flat plate portion provided in a seventeenth embodiment of the guide wire of the present invention.

  Hereinafter, the seventeenth embodiment of the guide wire of the present invention will be described with reference to this figure, but the description will focus on the differences from the above-described embodiment, and the description of the same matters will be omitted.

  The guide wire of the present embodiment is substantially the same as the fifteenth embodiment except that the configuration of the rigid portion is different.

  As shown in FIG. 27, in the flat plate portion 3T, the rigid portion 32 does not include a portion covering the side surface of the flexible portion 31. Thereby, the flat plate part 3T is easy to bend in the surface direction.

<Eighteenth embodiment>
FIG. 28 is a plan view showing a flat plate portion provided in the eighteenth embodiment of the guide wire of the present invention.

  Hereinafter, an eighteenth embodiment of the guide wire of the present invention will be described with reference to this drawing. However, the difference from the above-described embodiment will be mainly described, and the description of the same matters will be omitted.

  The guide wire of the present embodiment is substantially the same as the seventeenth embodiment except that the configuration of the rigid portion is different.

  As shown in FIG. 28, in the flat plate portion 3U, one of the two wire members 324 of the rigid portion of the seventeenth embodiment is omitted from the rigid portion 32. Thereby, the flat plate part 3T can be easily bent in the arrow G direction in FIG.

As mentioned above, although the guide wire of this invention was demonstrated about embodiment of illustration, this invention is not limited to this, Each part which comprises a guide wire is a thing of arbitrary structures which can exhibit the same function. Can be substituted. Moreover, arbitrary components may be added.
Moreover, you may combine each embodiment suitably.

DESCRIPTION OF SYMBOLS 1 Guide wire 2 1st wire 21 Outer diameter constant part 22 1st taper part 23 2nd taper part 24 Large diameter part 26 Tip side outer diameter constant part 27 Transition part 3, 3A, 3B, 3C, 3D, 3E, 3F, 3G, 3H, 3J, 3K, 3L, 3M, 3Q, 3R, 3S, 3T, 3U Flat plate portion 31 Flexible portion 310 Third base material 310A Fourth base material 311 Groove 311A Base end surface 32 Rigid portion 320 Second base material 320B 6th base material 321 Embedded part 322 Protruding part 322 'Convex part 323 Concave part 324 Wire material 35 Surface 36 Surface 37 Side surface 38 Side surface 4 Second wire 5 Coil 50 Gap 51 Fixing material 53 Fixing material 54 Wire 6 Joining portion 8 Resin coating layer DESCRIPTION OF SYMBOLS 10 Wire main body 100 1st preform | base_material 100A 5th preform | base_material 101A Tip surface 200, 200A Joined body 300 Boundary line 500 Boundary part

Claims (9)

Provided with a wire body having a plate-shaped flat plate at the tip,
The flat plate portion is composed of a first flat plate forming portion and a second flat plate forming portion made of different materials,
One flat plate forming portion of the first flat plate forming portion and the second flat plate forming portion is provided over the entire region in the width direction of the flat plate portion , and the entire region in the thickness direction of the flat plate portion. guide wire, characterized in that provided over.   The one flat plate forming portion of the first flat plate forming portion and the second flat plate forming portion has at least one embedded portion embedded in the other flat plate forming portion. Guide wire.   The guide wire according to claim 2, wherein the embedded portion extends in a direction intersecting with a longitudinal direction of the wire body. A plurality of the buried portions are provided,
4. The guide wire according to claim 2, wherein the embedded portions have different inclination directions with respect to the longitudinal direction of the wire main body and intersect at a central portion of the flat plate portion. A plurality of the buried portions are provided,
5. The guide wire according to claim 2, wherein each of the embedded portions is provided apart from each other along a longitudinal direction of the wire body.   One flat plate forming portion of the first flat plate forming portion and the second flat plate forming portion has a protruding portion that protrudes in the thickness direction of the flat plate portion from the other flat plate forming portion. The guide wire according to any one of claims 1 to 5.   The flat plate forming portion of one of the first flat plate forming portion and the second flat plate forming portion is stainless steel, and the other flat plate forming portion is a Ni-Ti alloy. The guide wire according to any one of the above.   The boundary between the first flat plate forming portion and the second flat plate forming portion intersects with the central axis of the wire main body in a plan view of the flat plate portion. Guide wire. The flat plate portion extends along the longitudinal direction of the wire body,
The guide wire according to any one of claims 1 to 8, wherein a boundary line between the first flat plate forming portion and the second flat plate forming portion is inclined with respect to a longitudinal direction of the flat plate portion.

Images