JPS55133345A - Mercaptoacyldipeptides - Google Patents

Mercaptoacyldipeptides

Info

Publication number: JPS55133345A
Authority: JP; Japan
Prior art keywords: mercaptoacyldipeptides
Prior art date: 1979-04-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP4402080A

Other languages

Japanese (ja)

Inventor

Enjieru Ondetsutei Migeeru

Puruseku Jiyoshipu

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ER Squibb and Sons LLC

Original Assignee

ER Squibb and Sons LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-04-02

Filing date

1980-04-02

Publication date

1980-10-17

1980-04-02 Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC

1980-10-17 Publication of JPS55133345A publication Critical patent/JPS55133345A/en

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

JP4402080A 1979-04-02 1980-04-02 Mercaptoacyldipeptides Pending JPS55133345A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2570179A	1979-04-02	1979-04-02

Publications (1)

Publication Number	Publication Date
JPS55133345A true JPS55133345A (en)	1980-10-17

Family

ID=21827594

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP4402080A Pending JPS55133345A (en)	1979-04-02	1980-04-02	Mercaptoacyldipeptides

Country Status (22)

Country	Link
JP (1)	JPS55133345A (en)
AT (1)	AT373577B (en)
AU (1)	AU537592B2 (en)
BE (1)	BE882601A (en)
CH (1)	CH645092A5 (en)
DE (1)	DE3012140A1 (en)
DK (1)	DK140480A (en)
ES (1)	ES490166A0 (en)
FR (1)	FR2453135A1 (en)
GB (1)	GB2045771B (en)
GR (1)	GR67752B (en)
HU (1)	HU181087B (en)
IE (1)	IE49653B1 (en)
IT (1)	IT1147332B (en)
LU (1)	LU82316A1 (en)
NL (1)	NL8001675A (en)
NO (1)	NO150360C (en)
NZ (1)	NZ193142A (en)
PH (1)	PH22024A (en)
PT (1)	PT71044A (en)
SE (1)	SE8002512L (en)
ZA (1)	ZA801527B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5692848A (en) *	1979-12-27	1981-07-27	Dainippon Pharmaceut Co Ltd	Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine
JP2009507917A (en) *	2005-09-13	2009-02-26	ウィリアムエイチ．シモンズ，	Thio-containing inhibitors of aminopeptidase P, compositions thereof and methods of use

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS56139455A (en)	1980-04-02	1981-10-30	Santen Pharmaceut Co Ltd	Sulfur-containing acylaminoacid
US4336950A (en) *	1980-09-08	1982-06-29	John Zepkowski	Sled
US4462943A (en) *	1980-11-24	1984-07-31	E. R. Squibb & Sons, Inc.	Carboxyalkyl amino acid derivatives of various substituted prolines
JPS57142967A (en) *	1981-02-27	1982-09-03	Dainippon Pharmaceut Co Ltd	N-(acylthioalkanoyloxy)succinimide and its use
US4512979A (en) *	1981-03-23	1985-04-23	Merck & Co., Inc.	Dipeptides containing thialysine and related amino acids as antihypertensives
US4382081A (en) *	1981-06-12	1983-05-03	E. R. Squibb & Sons, Inc.	Inhibitors of mammalian collagenase
IT1195287B (en) *	1981-11-05	1988-10-12	Ausonia Farma Srl	THIAZOLIC DERIVATIVE, PROCEDURE FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
US4434151A (en) *	1982-11-08	1984-02-28	Medi-Physics, Inc.	Bifunctional chelating agents
DE3243369A1 (en) *	1982-11-24	1984-05-24	Basf Ag, 6700 Ludwigshafen	BIS- (BENZOYLTHIO) CARBONIC ACIDS, THEIR PRODUCTION AND USE FOR THE PRODUCTION OF ACTIVE SUBSTANCES
US4642355A (en) *	1984-02-24	1987-02-10	Otsuka Pharmaceutical Factory, Inc.	Proline derivatives
US4560506A (en) *	1984-05-25	1985-12-24	E. R. Squibb & Sons, Inc.	Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides
DE3432307A1 (en) *	1984-09-03	1986-04-10	Boehringer Ingelheim KG, 6507 Ingelheim	AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS
DE3436569A1 (en) *	1984-10-05	1986-04-10	Boehringer Ingelheim KG, 6507 Ingelheim	AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS
US4894437A (en) *	1985-11-15	1990-01-16	The Upjohn Company	Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
WO1987002986A1 (en) *	1985-11-15	1987-05-21	The Upjohn Company	Novel renin inhibiting polypeptide analogs containing s-aryl-d- or l- or dl-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
JPH0662671B2 (en) *	1986-01-17	1994-08-17	株式会社大塚製薬工場	Proline derivative
EP0500989B1 (en) *	1991-02-27	1998-12-09	Lacer, S.A.	N-(alpha-substituted-pyridinyl) carbonyl dipeptide antihypertensive agents
FR2679564A1 (en) *	1991-07-23	1993-01-29	Inst Nat Sante Rech Med	NOVEL ACYLMERCAPTOALCANOLDIPEPTIDES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
US5504080A (en) *	1992-10-28	1996-04-02	Bristol-Myers Squibb Co.	Benzo-fused lactams
GB9310075D0 (en) *	1993-05-17	1993-06-30	Fujisawa Pharmaceutical Co	New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS559058A (en) *	1978-07-06	1980-01-22	Dainippon Pharmaceut Co Ltd	1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative

1980
- 1980-03-12 AU AU56380/80A patent/AU537592B2/en not_active Ceased
- 1980-03-14 GB GB8008696A patent/GB2045771B/en not_active Expired
- 1980-03-14 ZA ZA00801527A patent/ZA801527B/en unknown
- 1980-03-17 NZ NZ193142A patent/NZ193142A/en unknown
- 1980-03-17 PH PH23775A patent/PH22024A/en unknown
- 1980-03-18 GR GR61475A patent/GR67752B/el unknown
- 1980-03-21 NL NL8001675A patent/NL8001675A/en not_active Application Discontinuation
- 1980-03-26 FR FR8006711A patent/FR2453135A1/en active Granted
- 1980-03-28 DE DE19803012140 patent/DE3012140A1/en not_active Withdrawn
- 1980-03-28 IE IE638/80A patent/IE49653B1/en not_active IP Right Cessation
- 1980-03-31 NO NO800931A patent/NO150360C/en unknown
- 1980-04-01 HU HU8080774A patent/HU181087B/en not_active IP Right Cessation
- 1980-04-01 DK DK140480A patent/DK140480A/en not_active IP Right Cessation
- 1980-04-01 SE SE8002512A patent/SE8002512L/en not_active Application Discontinuation
- 1980-04-01 CH CH257180A patent/CH645092A5/en not_active IP Right Cessation
- 1980-04-01 LU LU82316A patent/LU82316A1/en unknown
- 1980-04-01 IT IT21110/80A patent/IT1147332B/en active
- 1980-04-01 PT PT71044A patent/PT71044A/en not_active IP Right Cessation
- 1980-04-01 ES ES490166A patent/ES490166A0/en active Granted
- 1980-04-02 JP JP4402080A patent/JPS55133345A/en active Pending
- 1980-04-02 AT AT0179480A patent/AT373577B/en not_active IP Right Cessation
- 1980-04-02 BE BE0/200091A patent/BE882601A/en not_active IP Right Cessation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS559058A (en) *	1978-07-06	1980-01-22	Dainippon Pharmaceut Co Ltd	1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5692848A (en) *	1979-12-27	1981-07-27	Dainippon Pharmaceut Co Ltd	Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine
JPS6318599B2 (en) *	1979-12-27	1988-04-19	Dainippon Pharmaceutical Co
JP2009507917A (en) *	2005-09-13	2009-02-26	ウィリアムエイチ．シモンズ，	Thio-containing inhibitors of aminopeptidase P, compositions thereof and methods of use

Also Published As

Publication number	Publication date
IE49653B1 (en)	1985-11-13
GB2045771B (en)	1983-01-26
NL8001675A (en)	1980-10-06
FR2453135B1 (en)	1983-06-17
PT71044A (en)	1980-05-01
NO150360B (en)	1984-06-25
ATA179480A (en)	1983-06-15
AT373577B (en)	1984-02-10
AU537592B2 (en)	1984-07-05
LU82316A1 (en)	1980-12-16
NO150360C (en)	1984-10-03
DE3012140A1 (en)	1980-10-23
ES8104200A1 (en)	1981-04-01
GR67752B (en)	1981-09-18
FR2453135A1 (en)	1980-10-31
HU181087B (en)	1983-05-30
IT1147332B (en)	1986-11-19
PH22024A (en)	1988-05-13
BE882601A (en)	1980-10-02
CH645092A5 (en)	1984-09-14
DK140480A (en)	1980-10-03
AU5638080A (en)	1980-10-09
SE8002512L (en)	1980-10-03
ZA801527B (en)	1981-03-25
NO800931L (en)	1980-10-03
ES490166A0 (en)	1981-04-01
NZ193142A (en)	1984-08-24
IE800638L (en)	1980-10-02
IT8021110A0 (en)	1980-04-01
GB2045771A (en)	1980-11-05

Publication	Publication Date	Title
CS216180A2 (en)	1984-12-14	Zpusob vyroby oplatek
EP0021287A3 (en)	1981-02-04	Multi-microprocessorsystem
CS375080A2 (en)	1985-08-15	Vstrikovaci cerpadlo
GB2045771B (en)	1983-01-26	Mercaptoacyldipeptides
CS458380A2 (en)	1985-06-13	Zpusob vyroby tripeptidamidu
CS486180A2 (en)	1985-09-17	Zpusob vyroby n-fosfonomethylglycinu
CS819480A2 (en)	1985-09-17	Bezpecnostni lyzarske vazani
DE3064894D1 (en)	1983-10-27	Fire-guard
CS265980A1 (en)	1985-07-16	Zpusob torkretovani vyzdivky hutnich agregatu rozptylovym kuzelem
CS819380A2 (en)	1985-08-15	Deskove bezpecnostni lyzarske vazani
CS458480A2 (en)	1985-05-15	Zpusob vyroby tripeptidamidu
CS149380A2 (en)	1984-01-16	Zpusob cisteni merkaptobenzothiazolu
DE3060490D1 (en)	1982-07-22	Trialkoxysilylthiopropionamides
CS518580A2 (en)	1984-02-13	Proslupni ustroji tkaciho stroje
DE3062361D1 (en)	1983-04-21	17-cycloalkylmethyl-6-methylene-morphinane-derivatives
CU21117A3 (en)	1988-02-15	Dea-steroids
CS175679A2 (en)	1985-06-13	Vodovaha
CA46372S (en)	1979-12-17	Sun-hole/windscreen-ii
CA46371S (en)	1979-12-17	Sun-hole/windscreen - iii
CA46370S (en)	1979-12-17	Sun-hole/windscreen - i
CA45704S (en)	1979-07-23	Citruspress
CA44955S (en)	1979-02-05	Citruspress
CS163482A2 (en)	1985-09-17	Povlakova hmota
CS527983A2 (en)	1985-08-15	Zpusob vyroby novych kondenzovanych derivatu
CS490279A1 (en)	1984-05-14	Zapojeni ridiciho delice napeti