WO2006102594A1 - Nucleoside prodrugs for treating viral infections - Google Patents

Abstract

Disclosed are prodrug compounds of Formula I, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.

Description

NUCLEOSIDE PRODRUGS FOR TREATING VIRAL INFECTIONS

CROSS REFERENCE TO RELATED PATENT APPLICATIONS

[0001] This application claims priority under 35 U.S.C. §119(e) of U.S. Provisional Application No. 60/665,045, filed March 23, 2005, the contents of which is incorporated by reference in its entirety.

TECHNICAL FIELD

[0002] The invention relates to the field of pharmaceutical chemistry, in particular to prodrug compounds, compositions and methods for treating viral infections in mammals mediated, at least in part, by a virus in the flaviviridae family of viruses.

BACKGROUND ART

References

[0003] The following publications are cited in this application as superscript numbers:

1. Giangaspero, et al. , Arch. Virol. Suppl. , 7: 53-62 (1993);

2. Giangaspero, et al, Int. J. STD. AIDS, 4(5): 300-302 (1993);

3. Yolken, et al, Lancet, 1(8637): 517-20 (1989);

4. Wilks, et al, Lancet, 1(8629): 107 (1989);

5. Giangaspero, et al, Lancet, 2: 110 (1988);

6. Potts, et al, Lancet, 1(8539): 972-973 (1987);

7. Cornberg, et al, "Hepatitis C: therapeutic perspectives." Forum (Genova), π_.(2): 154-62 (2001);

8. Dymock, et al , Antivir. Chem. Chemother. ϋ(2):79-96 (2000);

9. Devos, et al, International Patent Application Publication No. WO 02/18404 A2, published 7 March, 2002; 10. Sommadossi, et al. , International Patent Application Publication No. WO 01/90121, published 23 May, 2001;

11. Carroll, S. S., et al, International Patent Application Publication No. WO 02057287, published 25 July, 2002;

12. Carroll, S. S., et al, International Patent Application Publication No. WO 02057425, published 25 July, 2002;

13. Roberts, et al, U.S. Patent Application Serial No. 10/861 ,090, filed June 4, 2004.

14. Roberts, et al., U.S. Patent Application Serial No. 10/861,311, filed June 4, 2004.

[0004] AU of the above publications and applications are herein incorporated by reference in their entirety to the same extent as if each individual publication or application was specifically and individually indicated to be incorporated by reference in its entirety.

State of the Art

[0005] The Flaviviridae family of viruses is composed of three genera: pestivirus, flavivirus and hepacivirus (hepatitis C virus). Of these genera, flaviviruses and hepaciviruses represent important pathogens of man and are prevalent throughout the world. There are 38 flaviviruses associated with human disease, including the dengue fever viruses, yellow fever virus and Japanese encephalitis virus. Flaviviruses cause a range of acute febrile illnesses and encephalitic and hemorrhagic diseases. Hepaciviruses currently infect approximately 2 to 3% of the world population and cause persistent infections leading to chronic liver disease, cirrhosis, hepatocellular carcinoma and liver failure. Human pestiviruses have not been as extensively characterized as the animal pestiviruses. However, serological surveys indicate considerable pestivirus exposure in humans. Pestivirus infections in man have been implicated in several diseases including, but not likely limited to, congenital brain injury, infantile gastroenteritis and chronic diarrhea in human immunodeficiency virus (HIV) positive patients.^1'6

[0006] Currently, there are no antiviral pharmaceutical drugs to prevent or treat pestivirus or flavivirus infections. For hepacivirus, i.e., hepatitis C virus (HCV) infections, interferon alpha (IFN) is currently the only approved drug in the United States. HCV is a major causative agent for post-transfusion and for sporadic non-A, non-B hepatitis. Infection by HCV is insidious in a high proportion of chronically infected (and infectious) carriers who may not experience clinical symptoms for many years.

[0007] At present, the only acceptable treatment for chronic HCV is interferon (IFN-alpha) and this requires at least six (6) months of treatment and/or ribavirin, which can inhibit viral replication in infected cells and also improve liver function in some people.

[0008] IFN-alpha belongs to a family of naturally occurring small proteins with characteristic biological effects such as antiviral, immunoregulatory and antitumoral activities that are produced and secreted by most animal nucleated cells in response to several diseases, in particular viral infections. IFN-alpha is an important regulator of growth and differentiation affecting cellular communication and immunological control. Treatment of HCV with interferon, however, has limited long term efficacy with a response rate about 25%. In addition, treatment of HCV with interferon has frequently been associated with adverse side effects such as fatigue, fever, chills, headache, myalgias, arthralgias, mild alopecia, psychiatric effects and associated disorders, autoimmune phenomena and associated disorders and thyroid dysfunction. [0009] Ribavirin (1-β-D-ribofuranosyl-l H-l,2,-4-triazole-3-carboxamide), an inhibitor of inosine 5 '-monophosphate dehydrogenase (IMPDH), enhances the efficacy of IFN-alpha in the treatment of HCV. Despite the introduction of Ribavirin, more than 50% of the patients do not eliminate the virus with the current standard therapy of interferon-alpha (IFN) and Ribavirin. By now, standard therapy of chronic hepatitis C has been changed to the combination of PEG-IFN plus ribavirin. However, a number of patients still have significant side effects, primarily related to Ribavirin. Ribavirin causes significant hemolysis in 10-20% of patients treated at currently recommended doses, and the drug is both teratogenic and embryotoxic.

[0010] Other approaches are being taken to combat the virus. They include, for example, application of antisense oligonucleotides or ribozymes for inhibiting HCV replication. Furthermore, low-molecular weight compounds that directly inhibit HCV proteins and interfere with viral replication are considered as attractive strategies to control HCV infection. NS3/4A serine protease, ribonucleic acid (RNA) helicase, RNA-dependent RNA polymerase are considered as potential targets for new drugs.⁷'⁸

[0011] Devos, et al.⁹ describes purine and pyrimidine nucleoside derivatives and their use as inhibitors of HCV RNA replication. Sommadossi, et al.¹⁰ describes I¹, 2' or 3 '-modified nucleosides and their use for treating a host infected with HCV. Carroll, et al.¹¹'¹², describes nucleosides as inhibitors of RNA-dependent RNA viral polymerase.

[0012] Recently, Roberts, et al.¹³'¹⁴ disclosed that certain 7-(2'-substituted-β-D- ribofuranosyl)-4-amino-5-(optionally substituted ethyn-1-yl)-pyrrolo[2,3- d]pyrimidine compounds possess potent activity against HCV. These references are incorporated herein by reference in their entirety.

DETAILED DESCRIPTION

[0013] The embodiments are directed to novel compounds that are useful in the treatment of viral infections in mammals mediated at least in part by a virus in the flaviviridae family of viruses. Specifically the embodiments are directed to compounds of Formula I

I wherein

Y is selected from the group consisting of a bond, -CH₂- or -O-; each of A⁰ is independently selected from A¹, A² or W³ with the proviso that the compound of Formula I includes at least one A¹; A¹ Is:

A² is:

-

Y² is independently a bond, O, N(R^x), N(O)(R^x), N(OR^x), N(O)(OR^x), N(N(R^x)( R^x)), -S(O) _m2-, or -S(O)_m2-S(O)_m2-;

R² is independently H, R¹, R³ or R⁴ wherein each R⁴ is independently substituted with 0 to 3 R³ groups, or taken together at a carbon atom, two R² groups form a ring of 3 to 8 carbons and the ring may be substituted with 0 to 3 R³ groups;

W⁶ is W³ independently substituted with 1, 2, or 3 A³ groups;

A³ is:

Y¹ is independently O, S, N(R^x), N(O)(R^x), N(OR^x), N(O)(OR^x), or N(N(R^x)(

R^x));

W³ is W⁴ or W⁵;

W⁴ is R⁵, -C(Y¹)R⁵, -C(Y¹)W⁵, -SO₂R⁵, or -SO₂W⁵;

W⁵ is carbocycle or heterocycle wherein W⁵ is independently substituted with O to 3 R² groups;

R⁵ is R⁴ wherein each R⁴ is substituted with O to 3 R³ groups;

R⁴ is an alkyl of 1 to 18 carbon atoms, alkenyl of 2 to 18 carbon atoms, or alkynyl of 2 to 18 carbon atoms; R^x is independently H, R , W³, a protecting group, or the formula:

R¹ is independently H or an alkyl of 1 to 18 carbon atoms;

R^y is independently H, W³, R² or a protecting group;

R³ is R^3a, R^3b, R^3c or R^3d, provided that when R³ is bonded to a heteroatom, then R³ is R^3c or R^3d;

R^3a is F, Cl, Br, I, -CN, N₃ or -NO₂;

R^3b is Y¹;

R^3c is -R^x, -N(R^x)(R^x), -SR^x, -S(O)R^x, -S(O)₂R^x, -S(O)(OR^x), -S(O)₂(OR^x), -OC(Y¹)R^x, -OC(Y¹)OR^x, -OC(Y¹)(N( R^x)(R)^x,) -SC(Y¹)R^x, -SC(Y¹)OR^x, -SC(Y¹)(N(R^x)(R^x)), -N(R^x)C(Y¹)R^x, -N(R^x)C(Y¹)OR^x, or -N(R^x)C(Y¹)(N(R^xχR^x)) ;

R^3d is -C(Y¹)R^x, -C(Y¹)OR^x or -C(Y¹)(N(R^x)(R^x)); mla, ml c, and mid are independently 0 or 1; m2 is 0, 1 or 2; ml 2a is 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; ml 2b is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; ml 2c is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; and

T is selected from the group consisting of a) -C≡C-Z, wherein Z is selected from the group consisting of i) tri(C₁-C₄)alkylsilyl, -C(O)NZ¹Z², alkoxyalkyl, heteroaryl, and substituted heteroaryl, and phenyl substituted with 1 to 3 substituents selected from the group consisting of alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, aminoacyl, amidino, amino, substituted amino, carboxyl, carboxyl ester, cyano, cycloalkyl, substituted cycloalkyl, cycloalkoxy, substituted cycloalkoxy, guanidino, halo, heteroaryl, substituted heteroaryl, hydrazino, hydroxyl, nitro, thiol, and -S(O)_mZ³; wherein Z¹ and Z² are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, amino, substituted amino, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic provided that only one of Z¹ and Z² is amino or substituted amino, and further wherein Z¹ and Z², together with the nitrogen atom pendant thereto, form a heterocyclic or substituted heterocyclic;

Z³ is selected from the group consisting of alkyl, substituted alkyl, amino, substituted amino, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic; and m is an integer equal to 0, 1 or 2; ii) -C(O)OZ¹⁴ , wherein Z¹⁴ is hydrogen, alkyl or substituted alkyl; b) -CH=CH-Q², wherein Q² is selected from hydrogen or cw-methoxy; C) -C(O)H; d) -CH=NNHZ¹⁵, wherein Z¹⁵ is H or alkyl; e) -CH=N(OZ¹⁵), wherein Z¹⁵ is as defined above; f) -CH(OZ¹⁶)₂, wherein Z¹⁶ is (C₃ - C₆)alkyl; g) -B(OZ¹⁵)₂, wherein Z¹⁵ is as defined above; and

.I) -NO₂; and pharmaceutically acceptable salts or partial salts thereof; wherein A⁰ is a prodrug moiety; provided that the prodrug moiety is not selected from the group consisting of acyl, oxyacyl, phosphonate, phosphate esters, phosphate, phosphonamidate, phosphorodiamidate, phosphor amidate monoester, cyclic phosphoramidate, cyclic phosphorodiamidate, phosphoramidate diester, -C(O)CHR^fNH₂, a prodrug of the formula:

a prodrug of the formula:

wherein R^e is selected from the group consisting of alkyl, substutituted alkyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic;

R^f is selected from the group consisiting of hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted hetereoaryl, heterocyclic, substituted heterocyclic, and a sidechain of an amino acid; and

R^sis hydrogen or alkyl.

[0014] More preferably, Z is selected from the group consisting of phenyl, -C(O)NH₂, -Si(CH₃)₃, pyrid-2-yl, 4-methoxyphenyl, and -CH(OCH₂CH₃)₂. [0015] In another preferred embodiment T is -C≡C-Z, Z is -C(O)OZ¹⁴, and Z¹⁴ is H or alkyl.

[0016] In another preferred embodiment, T is -C≡C-Z and Z is -C(O)OH. [0017] In another preferred embodiment, T is -CH=CH-Q , wherein Q is selected from hydrogen or cis-methoxy. [0018] In another preferred embodiment, T is -C(=O)H. [0019] In another preferred embodiment, T is -CH=NNHZ¹⁵ wherein Z¹⁵ is independently selected from the group consisting of hydrogen and alkyl. [0020] In another preferred embodiment, T is -CH=N(OZ¹⁵) wherein Z¹⁵ is independently selected from the group consisting of hydrogen and alkyl. [0021] In another preferred embodiment, T is -CH(OZ¹⁶)₂ wherein Z¹⁶ is independently (C₃-C₆)alkyl.

[0022] In another preferred embodiment, T is -B(OZ¹⁵)₂, wherein Z¹⁵ is independently selected from the group consisting of hydrogen and alkyl. [0023] In another preferred embodiment, T is -NO₂;

[0024] Compounds of the embodiments can be either active as antiviral agents or can be useful as intermediates in the preparation of antiviral agents as described herein. [0025] The embodiments are also directed to pharmaceutical compositions comprising a pharmaceutically acceptable diluent and a therapeutically effective amount of a compound as described herein or mixtures of one or more of such compounds.

[0026] The embodiments are still further directed to methods for treating a viral infection mediated at least in part by a virus in the flaviviridae family of viruses, such as HCV, in mammals which methods comprise administering to a mammal, that has been diagnosed with said viral infection or is at risk of developing said viral infection, a pharmaceutical composition comprising a pharmaceutically acceptable diluent and a therapeutically effective amount of a compound as described herein or mixtures of one or more of such compounds. [0027] In yet another embodiment, methods of treating or preventing viral infections in mammals are provided wherein the compounds of the embodiments are administered in combination with the administration of a therapeutically effective amount of one or more agents active against HCV. Active agents against HCV include, but are not limited to, ribavirin, levovirin, viramidine, thymosin alpha- 1, an inhibitor of NS3 serine protease, and inhibitor of inosine monophosphate dehydrogenase, interferon-alpha or pegylated interferon-alpha, either alone or in combination with Ribavirin, levovirin or viramidine. Preferably the additional agent active against HCV is interferon-alpha or pegylated interferon-alpha alone or in combination with Ribavirin, levovirin or viramidine.

MODES FOR CARRYING OUT THE INVENTION

[0028] The present embodiments are directed to prodrug compounds, compositions and methods for treating flaviviridae viruses, such as hepatitis C virus infections. However, prior to describing the embodiments in detail, the following terms will first be defined:

Definitions

[0029] As used herein and unless otherwise defined herein, the term "alkyl" refers to alkyl groups having from 1 to 30 carbon atoms and more preferably 1 to 20 carbon atoms. This term is exemplified by groups such as methyl, ethyl, n- propyl, iyo-propyl, w-butyl, /-butyl, ra-pentyl and the like. [0030] "Substituted alkyl" refers to an alkyl group having from 1 to 3, and preferably 1 to 2, substituents selected from the group consisting of alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, oxyacyl, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy, substituted aryloxy, cyano, halogen, hydroxyl, nitro, carboxyl, carboxyl esters, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic. [0031] "Alkoxy" refers to the group "alky1-O" which includes, by way of example, methoxy, ethoxy, n-propoxy, iso-propoxy, n-butoxy, t-butoxy, sec- butoxy, n-pentoxy and the like.

[0032] "Substituted alkoxy" refers to the group "substituted alky1-O-^M. [0033] "Alkoxyalkyl" refers to a linear or branched alkyl group as defined herein having as a substituent an alkoxy group as defined herein. [0034] "Trialkylsilyl" refers to the group -Si(R¹⁰XR¹¹XR¹²), wherein R¹⁰, Rⁿ, and R¹² are alkyl groups, as defined herein.

[0035] "Acyl" refers to the groups alky1-C(O)-, substituted alkyl-C(O)-, alkenyl-C(O)-, substituted alkenyl-C(O)-, alkynyl-C(O)-, substituted alkynyl- C(O)-, cycloalkyl-C(O)-, substituted cycloalkyl-C(O)-, aryl-C(O)-, substituted aryl-C(O)-, heteroaryl-C(O)-, substituted heteroaryl-C(O), heterocyclic-C(O)-, and substituted heterocyclic-C(O)-.

[0036] "Acylamino" refers to the group -C(O)NR^aR^a where each R^a is independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic and wherein each R^a is joined to form together with the nitrogen atom a heterocyclic or substituted heterocyclic ring. [0037] "Acyloxy" refers to the groups alkyl-C(O)O-, substituted alkyl-C(O)O-, alkenyl-C(O)O-, substituted alkenyl-C(O)O-, alkynyl-C(O)O-, substituted alkynyl-C(O)O-, aryl-C(O)O-, substituted aryl-C(O)O-, cycloalkyl-C(O)O-, substituted cycloalkyl-C(O)O-, heteroaryl-C(O)O-, substituted heteroaryl-C(O)O- , heterocyclic-C(O)O-, and substituted heterocyclic-C(O)O-. [0038] "Oxyacyl" refers to the groups alkyl-OC(O)-, substituted alkyl-OC(O)-, alkenyl-OC(O)-, substituted alkenyl-OC(O)-, alkynyl-OC(O)-, substituted alkynyl-OC(O)-, aryl-OC(O)-, substituted aryl-OC(O)-, cycloalkyl-OC(O)-, substituted cycloalkyl-OC(O)-, heteroaryl-OC(O)-, substituted heteroaryl-OC(O)- , heterocyclic-OC(O)-, and substituted heterocyclic-OC(O)-. [0039] Unless otherwise defined herein, the term "alkenyl" refers to alkenyl groups having from 2 to 30 carbon atoms, and preferably 2 to 20 carbon atoms, and having at least 1 and preferably from 1-2 sites of alkenyl unsaturation. Such groups are exemplified by vinyl (ethen-1-yl), allyl, but-3-en-l-yl, and the like. [0040] "Substituted alkenyl" refers to alkenyl groups having from 1 to 3 substituents, and preferably 1 to 2 substituents, selected from the group consisting of alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy, substituted aryloxy, cyano, halogen, hydroxyl, nitro, carboxyl, carboxyl esters, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic with the proviso that any hydroxyl substitution is not attached to a vinyl (unsaturated) carbon atom. Preferred substituted alkenyl groups are selected from, but not limit to, 2,2-difluoroethen-l-yl, 2-methoxyethen-l-yl, and the like.

[0041] It is understood that the term "substituted alkenyl" includes both E (cis) and Z (trans) isomers as appropriate. The isomers can be pure isomeric compounds or mixtures of E and Z components.

[0042] Unless otherwise defined herein, the term "alkynyl" refers to an unsaturated hydrocarbon having at least 1 site of alkynyl unsaturation and having from 2 to 30 carbon atoms and more preferably 2 to 20 carbon atoms. Preferred alkynyl groups are selected from but not limit to ethyn-1-yl, propyn-1-yl, propyn- 2-yl, l-methylprop-2-yn-l-yl, butyn-1-yl, butyn-2-yl, butyn-3-yl, and the like. [0043] "Substituted alkynyl" refers to alkynyl groups having from 1 to 3 substituents, and preferably 1 to 2 substituents, selected from the group consisting of alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy, substituted aryloxy, cyano, halogen, hydroxyl, nitro, carboxyl, carboxyl esters, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic. Preferred substituted alkynyl groups are selected from but not limit to 2-fluoroethyn-l-yl, 3,3,3-trifluoropropyn-l-yl, 3-aminopropyn-l-yl, 3-hydroxypropyn-l-yl, and the like. [0044] "Amino" refers to the group -NH₂.

[0045] "Substituted amino" refers to the group -NR'R" where R' and R" are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic and where R' and R" are joined, together with the nitrogen bound thereto to form a heterocyclic or substituted heterocyclic group provided that R' and R" are both not hydrogen. When R' is hydrogen and R" is alkyl, the substituted amino group is sometimes referred to herein as alkylamino. When R' and R" are alkyl, the substituted amino group is sometimes referred to herein as dialkylamino.

[0046] "Amidino" refers to the group -CC=NR^)R¹⁰R¹ * where R¹⁰, R¹¹, and R¹² are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, heteroaryl, substituted heteroaryl, heterocyclyl, and substituted heterocyclyl and where R¹⁰ and R¹¹ are optionally joined together with the nitrogen bound thereto to form a heterocyclic or substituted heterocyclic group, and wherein alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic are as defined herein. [0047] "Aminoacyl" refers to the groups -NR^bC(O)alkyl, -NR^bC(O)substituted alkyl, -NR^bC(O)cycloalkyl, -NR^bC(O)substituted cycloalkyl, -NR^bC(O)alkenyl, -NR^bC(O)substituted alkenyl, -NR^bC(O)alkynyl, -NR^bC(O)substituted alkynyl, -NR^bC(O)aryl, -NR^bC(O)substituted aryl, -NR^bC(O)heteroaryl, -NR^bC(O)substituted heteroaryl, -NR^bC(O)heterocyclic, and - NR^bC(O)substituted heterocyclic where R^b is hydrogen or alkyl. [0048] "Aryl" or "Ar" refers to a monovalent aromatic carbocyclic group of from 6 to 14 carbon atoms having a single ring (e.g., phenyl) or multiple condensed rings (e.g., naphthyl or anthryl) which condensed rings may or may not be aromatic (e.g., 2-benzoxazolinone, 2H-l,4-benzoxazin-3(4H)-one-7-yl, and the like) provided that the point of attachment is at an aromatic carbon atom.

Preferred aryls include phenyl and naphthyl.

[0049] "Substituted aryl", including "substituted phenyl" refers to aryl groups or phenyl groups which are substituted with from 1 to 3 substituents, and preferably 1 to 2 substituents, selected from the group consisting of hydroxyl, acyl, acylamino, acyloxy, alkyl, substituted alkyl, alkoxy, substituted alkoxy, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy, substituted aryloxy, cycloalkoxy, substituted cycloalkoxy, carboxyl, carboxyl esters, cyano, thiol, thioalkyl, substituted thioalkyl, thioaryl, substituted thioaryl, thioheteroaryl, substituted thioheteroaryl, thiocycloalkyl, substituted thiocycloalkyl, thioheterocyclic, substituted thioheterocyclic, cycloalkyl, substituted cycloalkyl, halo, nitro, heteroaryl, substituted heteroaryl, heterocyclic, substituted heterocyclic, heteroaryloxy, substituted heteroaryloxy, heterocyclyloxy, and substituted heterocyclyloxy.

[0050] "Aryloxy" refers to the group aryl-O- that includes, by way of example, phenoxy, naphthoxy, and the like.

[0051] "Substituted aryloxy" refers to substituted aryl-O- groups.

[0052] "Carboxyl" and "carboxylic acid" refers to -COOH or salts thereof.

[0053] "Carboxyl esters" refers to the groups -C(O)O-alkyl,

-C(O)O-substituted alkyl, -C(O)O-aryl, and -C(O)O-substituted aryl wherein alkyl, substituted alkyl, aryl and substituted aryl are as defined herein.

[0054] "Cyano" refers to the group -CN.

[0055] "Cycloalkyl" refers to cyclic alkyl groups of from 3 to 10 carbon atoms having single or multiple cyclic rings one or more of which may be aromatic or heteroaromatic provided that the point of attachment is through a cycloalkyl ring atom. Such groups include, by way of example, adamantyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclooctyl and the like.

[0056] "Substituted cycloalkyl" refers to a saturated or unsaturated, but not aromatic, cycloalkyl having from 1 to 5 substituents selected from the group consisting of oxo (=O), thioxo (=S), alkyl, substituted alkyl, alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy/substituted aryloxy, cyano, halogen, hydroxyl, nitro, carboxyl, carboxyl esters, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic.

[0057] "Cycloalkenyl" refers to non-aromatic cyclic alkyl groups of from 3 to

10 carbon atoms having single or multiple cyclic rings and having at least one

>C=C< ring unsaturation and preferably from 1 to 2 sites of >C=C< ring unsaturation.

[0058] "Substituted cycloalkyl" and "substituted cycloalkenyl" refers to a cycloalkyl or cycloalkenyl group having from 1 to 5 or preferably 1 to 3 substituents selected from the group consisting of alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, oxyacyl, amino, substituted amino, aminoacyl, aryl, substituted aryl, aryloxy, substituted aryloxy, cyano, halogen, hydroxyl, nitro, carboxyl, carboxyl esters, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic.

[0059] "Cycloalkoxy" refers to -O-cycloalkyl groups.

[0060] "Substituted cycloalkoxy" refers to -O-substituted cycloalkyl groups.

[0061] "Formyl" refers to HC(O)-.

[0062] "Guanidino" refers to the group -NHC(=NH)NH₂.

[0063] "Halo" or "halogen" refers to fluoro, chloro, bromo, and iodo, and preferably is fluoro or chloro.

[0064] "Heteroaryl" refers to an aromatic group of from 1 to 10 carbon atoms and 1 to 4 heteroatoms selected from the group consisting of oxygen, nitrogen, sulfur in the ring. The sulfur and nitrogen heteroatoms atoms may also be present in their oxidized forms, such as >N(O), >S(O) and >S(O)₂. Such heteroaryl groups can have a single ring (e.g., pyridyl or furyl) or multiple condensed rings

(e.g., indolizinyl or benzothienyl) wherein the condensed rings may or may not be aromatic and/or contain a heteroatom provided that the point of attachment is through an atom of the aromatic heteroaryl group. Preferred heteroaryls include pyridyl, pyrrolyl, thienyl, indolyl, thiophenyl, and furyl.

[0065] "Substituted heteroaryl" refers to heteroaryl groups that are substituted with from 1 to 3 substituents selected from the same group of substituents defined for substituted aryl.

[0066] "Heteroaryloxy" refers to the group -O-heteroaryl and "substituted heteroaryloxy" refers to the group -O-substituted heteroaryl. [0067] "Heterocycle" or "heterocyclic" or "heterocycloalkyl" or "heterocyclyl" refers to a saturated or unsaturated group (but not heteroaryl) having a single ring or multiple condensed rings, from 1 to 10 carbon atoms and from 1 to 4 hetero atoms selected from the group consisting of nitrogen, oxygen, sulfur, >S(O), and

>S(O)₂ within the ring wherein, in fused ring systems, one or more the rings can be cycloalkyl, aryl or heteroaryl provided that the point of attachment is through the heterocyclic ring.

[0068] "Substituted heterocyclic" or "substituted heterocycloalkyl" refers to heterocycle groups that are substituted with from 1 to 3 of the same substituents as defined for substituted cycloalkyl.

[0069] Examples of heterocycles and heteroaryls include, but are not limited to, azetidine, pyrrole, imidazole, pyrazole, pyridine, pyrazine, pyrimidine, pyridazine, indolizine, isoindole, indole, dihydroindole, indazole, purine, quinolizine, isoquinoline, quinoline, phthalazine, naphthylpyridine, quinoxaline, quinazoline, cinnoline, pteridine, carbazole, carboline, phenanthridine, acridine, phenanthroline, isothiazole, phenazine, isoxazole, phenoxazine, phenothiazine, imidazolidine, imidazoline, piperidine, piperazine, indoline, phthalimide,

1 ,2,3,4-tetrahydroisoquinoline, 4,5,6,7-tetrahydrobenzo[b]thiophene, thiazole, thiazolidine, thiophene, benzo[b]thiophene, morpholinyl, thiomorpholinyl (also referred to as thiamorpholinyl), piperidinyl, pyrrolidine, tetrahydrofuranyl, and the like.

[0070] "Heterocyclyloxy" refers to the group -O-heterocyclic and "substituted heterocyclyloxy" refers to the group -O-substituted heterocyclic.

[0071] "Hydrazino" refers to the group -NHNH₂.

[0072] "Hydroxy" and "hydroxyl" refers to the group -OH.

[0073] "Nitro" refers to the group -NO₂.

[0074] "Phosphate" refers to the groups -OP(O)(OH)₂ (monophosphate or phospho), -OP(O)(OH)OP(O)(OH)₂ (diphosphate or diphospho) and

-OP(O)(OH)OP(O)(OH)OP(O)(OH)₂ (triphosphate or triphospho) or salts thereof including partial salts thereof. It is understood, of course, that the initial oxygen of the mono-, di- and triphosphate (phospho, diphospho and triphospho) includes the oxygen atom at, for example, the 5-position of the ribose sugar. [0075] "Phosphate esters" refers to the mono-, di- and tri-phosphate groups described above wherein one or more of the hydroxyl groups is replaced by an alkoxy group.

[0076] "Phosphonate" refers to the groups -OP(O)(R^j)(OH) or -OP(O)(RO(OR¹) or salts thereof including partial salts thereof, wherein each R¹ is independently selected from hydrogen, alkyl, substituted alkyl, carboxylic acid, and carboxyl ester. It is understood, of course, that the initial oxygen of the phosphonate includes the oxygen atom at, for example, the 5-position of the ribose sugar. [0077] "Phosphorodiamidate" refers to the group:

wherein each Rⁿmay be the same or different and each is hydrogen, alkyl, substituted alkyl, cycloalkyl, or substituted cycloalkyl. A particularly preferred phosphorodiamidate is the following group:

[0078] "Phosphoramidate monoester" refers to the group below, wherein R^f and R^s are as defined above. In a preferred embodiment R^f is derived from an L- amino acid.

[0079] "Phosphoramidate diester" refers to the group below, wherein R^e, R^f and R^g are as defined above. In a preferred embodiment R^f is derived from an L- amino acid.

[0080] "Cyclic phosphoramidate" refers to the group below, wherein n is 1 to 3, more preferably n is 1 to 2.

[0081] "Cyclic phosphorodiamidate" refers to the group below, wherein n is 1 to 3, more preferably n is 1 to 2.

[0082] "Phosphonamidate" refers to the group below, wherein R⁰ is hydrogen, alkyl, substituted alkyl, cycloalkyl, or substituted cycloalkyl.

[0083] "Thiol" refers to the group -SH.

[0084] "Thioalkyl" or "alkylthioether" or "thioalkoxy" refers to the group -S-alkyl.

[0085] "Substituted thioalkyl" or "substituted alkylthioether" or "substituted thioalkoxy" refers to the group -S-substituted alkyl.

[0086] "Thiocycloalkyl" refers to the groups -S-cycloalkyl and "substituted thiocycloalkyl" refers to the group -S-substituted cycloalkyl. [0087] "Thioaryl" refers to the group -S-aryl and "substituted thioaryl" refers to the group -S-substituted aryl.

[0088] "Thioheteroaryl" refers to the group -S-heteroaryl and "substituted thioheteroaryl" refers to the group -S-substituted heteroaryl. [0089] "Thioheterocyclic" refers to the group -S-heterocyclic and "substituted thioheterocyclic" refers to the group -S-substituted heterocyclic. [0090] The term "amino acid sidechain" refers to the R^j substituent of α-amino acids of the formula R^kNHCH(R^j)COOH where R^j is selected from the group consisting of hydrogen, alkyl, substituted alkyl and aryl and R^k is hydrogen or together with R^J and the nitrogen and carbon atoms bound thereto respectively form a heterocyclic ring. Preferably, the α-amino acid sidechain is the sidechain one of the twenty naturally occurring L amino acids. [0091] The term "prodrug" as used herein refers to any compound that when administered to a biological system generates the drug substance, i.e. active ingredient, as a result of spontaneous chemical reaction(s), enzyme catalyzed chemical reaction(s), photolysis, and/or metabolic chemical reaction(s). A prodrug is thus a covalently modified analog or latent form of a therapeutically- active compound.

[0092] "Prodrug moiety" means a labile functional group which separates from the active inhibitory compound during metabolism, systemically, inside a cell, by hydrolysis, enzymatic cleavage, or by some other process (Bundgaard, Hans, "Design and Application of Prodrugs" in Textbook of Drug Design and Development (1991), P. Krogsgaard-Larsen and H. Bundgaard, Eds. Harwood Academic Publishers, pp. 113-191, herein incorporated by reference in its entirety). Enzymes which are capable of an enzymatic activation mechanism with the phosphonate prodrug compounds of the embodiments include, but are not limited to, amidases, esterases, microbial enzymes, phospholipases, cholinesterases, and phosphases. Prodrug moieties can serve to enhance solubility, absorption and lipophilicity to optimize drug delivery, bioavailability and efficacy.

[0093] Exemplary prodrug moieties include the hydrolytically sensitive or labile acyloxymethyl esters -CH₂OC(=O)R^d and acyloxymethyl carbonates -CH₂OC(=O)OR^d where R^d is C₁-C₆alkyl, C₁-C₆substituted alkyl, C₆-C₂₀aryl or C₆-C₂₀substituted aryl. The acyloxyalkyl ester was first used as a prodrug strategy for carboxylic acids and then applied to phosphates and phosphonates by Farquhar et al (1983) J Pharm. Sci. 72: 324; also US Patent Nos. 4816570, 4968788, 5663159 and 5792756; all of which are incorporated herein by reference in their entirety. In certain compounds of the embodiments, a prodrug moiety is part of a phosphonate group. Subsequently, the acyloxyalkyl ester was used to deliver phosphonic acids across cell membranes and to enhance oral bioavailability. A close variant of the acyloxyalkyl ester, the alkoxycarbonyloxyalkyl ester (carbonate), may also enhance oral bioavailability as a prodrug moiety in the compounds of the combinations of the embodiments. An exemplary acyloxymethyl ester is pivaloyloxymethoxy, (POM) -CH₂OC(=O)C(CH3)3- An exemplary acyloxymethyl carbonate prodrug moiety is pivaloyloxymethylcarbonate (POC) -CH₂OC(=O)OC(CH₃)₃. [0094] The phosphonate group may be a phosphonate prodrug moiety. The prodrug moiety may be sensitive to hydrolysis, such as, but not limited to a pivaloyloxymethyl carbonate (POC) or POM group. Alternatively, the prodrug moiety may be sensitive to enzymatic potentiated cleavage, such as a lactate ester or a phosphonamidate-ester group.

[0095] Aryl esters of phosphorus groups, especially phenyl esters, are reported to enhance oral bioavailability (DeLambert et al (1994) J Med. Chem. 37: 498, herein incorporated by reference in its entirety). Phenyl esters containing a carboxylic ester ortho to the phosphate have also been described (Khamnei and Torrence, (1996) J Med. Chem. 39:4109-4115, herein incorporated by reference in its entirety). Benzyl esters are reported to generate the parent phosphonic acid. In some cases, substituents at the ortho-or para-position may accelerate the hydrolysis. Benzyl analogs with an acylated phenol or an alkylated phenol may generate the phenolic compound through the action of enzymes, e.g. esterases, oxidases, etc., which in turn undergoes cleavage at the benzylic C-O bond to generate the phosphoric acid and the quinone methide intermediate. Examples of this class of prodrugs are described by Mitchell et al (1992) J Chem. Soc. Perkin Trans. /2345; Brook et al WO 91/19721, all of which are herein incorporated by reference in its entirety. Still other benzylic prodrugs have been described containing a carboxylic ester-containing group attached to the benzylic methylene (Glazier et al WO 91/19721, herein incorporated by reference in its entirety). Thio-containing prodrugs are reported to be useful for the intracellular delivery of phosphonate drugs. These proesters contain an ethylthio group in which the thiol group is either esterified with an acyl group or combined with another thiol group to form a disulfide. Deesterification or reduction of the disulfide generates the free thio intermediate which subsequently breaks down to the phosphoric acid and episulfide (Puech et al (1993) Antiviral Res., 22: 155-174; Benzaria et al (1996) J Med. Chem. 39: 4958, all of which are herein incorporated by reference in their entirety). Cyclic phosphonate esters have also been described as prodrugs of phosphorus-containing compounds (Erion et al, US Patent No. 6312662, herein incorporated by reference in its entirety). [0096] The term "pharmaceutically acceptable salt" refers to pharmaceutically acceptable salts of a compound, which salts are derived from a variety of organic and inorganic counter ions well known in the art and include, by way of example only, sodium, potassium, calcium, magnesium, ammonium, tetraalkylammonium, and the like; and when the molecule contains a basic functionality, salts of organic or inorganic acids, such as hydrochloride, hydrobromide, tartrate, mesylate, acetate, maleate, oxalate and the like. [0097] The term "pharmaceutically acceptable partial salts" refers to compounds having a substituent capable of having more than one group form a salt but less than the maximum amount of such groups actually form a salt. For example, a diphospho group can form a plurality of salts and, if only partially ionized, the resulting group is sometimes referred to herein as a partial salt. [0098] "Carbocycle" means a saturated, unsaturated or aromatic ring having 3 to 7 carbon atoms as a monocycle or 7 to 12 carbon atoms as a bicycle. Monocyclic carbocycles have 3 to 6 ring atoms, still more typically 5 or 6 ring atoms. Bicyclic carbocycles have 7 to 12 ring atoms, e.g. arranged as a bicyclo [4,5], [5,5], [5,6] or [6,6] system, or 9 or 10 ring atoms arranged as a bicyclo [5,6] or [6,6] system. Examples of monocyclic carbocycles include cyclopropyl, cyclobutyl, cyclopentyl, 1-cyclopent-l-enyl, l-cyclopent-2-enyl, l-cyclopent-3- enyl, cyclohexyl, 1-cyclohex-l-enyl, l-cyclohex-2-enyl, l-cyclohex-3-enyl, phenyl, spiryl and naphthyl.

[0099] "Linker" or "link" means a chemical moiety comprising a covalent bond or a chain of atoms that covalently attaches a phosphonate group to a drug. Linkers include portions of substituents A¹ and A³ enumerated in Formula I which include moieties such as: repeating units of alkyloxy (e.g. polyethylenoxy, PEG, polymethyleneoxy) and alkylamino (e.g. polyethyleneamino, Jeffamine™); and diacid ester and amides including succinate, succinamide, diglycolate, malonate, and caproamide.

[0100] The term "crural" refers to molecules which have the property of non- superimposability of the mirror image partner, while the term "achiral" refers to molecules which are superimposable on their mirror image partner. [0101] The term "stereoisomers" refers to compounds which have identical chemical constitution, but differ with regard to the arrangement of the atoms or groups in space.

[0102] "Diastereomer" refers to a stereoisomer with two or more centers of chirality and whose molecules are not mirror images of one another. Diastereomers have different physical properties, e.g. melting points, boiling points, spectral properties, and reactivities. Mixtures of diastereomers may separate under high resolution analytical procedures such as electrophoresis and chromatography.

[0103] "Enantiomers" refer to two stereoisomers of a compound which are non- superimposable mirror images of one another.

[0104] Stereochemical definitions and conventions used herein generally follow S. P. Parker, Ed., McGraw-Hill Dictionary of Chemical Terms (1984) McGraw- Hill Book Company, New York; and Eliel, E. and Wilen, S., Stereochemistry of Organic Compounds (1994) John Wiley & Sons, Inc., New York. Many organic compounds exist in optically active forms, i.e., they have the ability to rotate the plane of plane-polarized light. In describing an optically active compound, the prefixes D and L or R and S are used to denote the absolute configuration of the molecule about its chiral center(s). The prefixes d and 1, D and L, or (+) and (-) are employed to designate the sign of rotation of plane-polarized light by the compound, with (-) or 1 meaning that the compound is levorotatory. A compound prefixed with (+) or d is dextrorotatory. For a given chemical structure, these stereoisomers are identical except that they are mirror images of one another. A specific stereoisomer may also be referred to as an enantiomer, and a mixture of such isomers is often called an enantiomeric mixture. A 50:50 mixture of enantiomers is referred to as a racemic mixture or a racemate, which may occur where there has been no stereoselection or stereospecifϊcity in a chemical reaction or process. The terms "racemic mixture" and "racemate" refer to an equimolar mixture of two enantiomeric species, devoid of optical activity. [0105] It is understood that in all substituted groups defined above, polymers arrived at by defining substituents with further substituents to themselves (e.g., substituted aryl having a substituted aryl group as a substituent which is itself substituted with a substituted aryl group, etc.) are not intended for inclusion herein. In such cases, the maximum number of such substituents is three. That is to say that each of the above definitions is constrained by a limitation that, for example, substituted aryl groups are limited to -substituted aryl-(substituted aryl)-substituted aryl.

[0106] Similarly, it is understood that the above definitions are not intended to include impermissible substitution patterns (e.g., methyl substituted with 5 fluoro groups or a hydroxyl group alpha to ethenylic or acetylenic unsaturation). Such impermissible substitution patterns are well known to the skilled artisan.

Protecting Groups

[0107] In the context of the present embodiments, embodiments of protecting groups include prodrug moieties and chemical protecting groups. [0108] Protecting groups are available, commonly known and used, and are optionally used to prevent side reactions with the protected group during synthetic procedures, i.e. routes or methods to prepare the compounds of the embodiments. For the most part the decision as to which groups to protect, when to do so, and the nature of the chemical protecting group "PRT" will be dependent upon the chemistry of the reaction to be protected against (e.g., acidic, basic, oxidative, reductive or other conditions) and the intended direction of the synthesis. The PRT groups do not need to be, and generally are not, the same if the compound is substituted with multiple PRT. In general, PRT will be used to protect functional groups such as carboxyl, hydroxyl or amino groups and to thus prevent side reactions or to otherwise facilitate the synthetic efficiency. The order of deprotection to yield free, deprotected groups is dependent upon the intended direction of the synthesis and the reaction conditions to be encountered, and may occur in any order as determined by the artisan. [0109] Various functional groups of the compounds of the embodiments may be protection. For example, protecting groups for -OH groups (whether hydroxyl, carboxylic acid, phosphonic acid, or other functions) are embodiments of "ether- or ester-forming groups". Ether- or ester-forming groups are capable of functioning as chemical protecting groups in the synthetic schemes set forth herein. However, some hydroxyl and thio protecting groups are neither ether- nor ester-forming groups, as will be understood by those skilled in the art, and are included with amides, discussed below.

[0110] A very large number of hydroxyl protecting groups and amide-forming groups and corresponding chemical cleavage reactions are described in "Protective Groups in Organic Chemistry", Theodora W. Greene (John Wiley & Sons, Inc., New York, 1991, ISBN 0-471-62301-6) ("Greene"). See also Kocienski, Philip J.; "Protecting Groups" (Georg Thieme Verlag Stuttgart, New York, 1994), which is incorporated by reference in its entirety herein. In particular Chapter I, Protecting Groups: An Overview, pages 1-20, Chapter 2, Hydroxyl Protecting Groups, pages 21-94, Chapter 3, Diol Protecting Groups, pages 95-117, Chapter 4, Carboxyl Protecting Groups, pages 118-154, Chapter 5, Carbonyl Protecting Groups, pages 155-184. For protecting groups for carboxylic acid, phosphonic acid, phosphonate, sulfonic acid and other protecting, groups for acids see Greene as set forth below. Such groups include by way of example and not limitation, esters, amides, hydrazides, and the like.

Ether- and Ester-forming protecting groups

[0111] Ester-forming groups include: (1) phosphonate ester-forming groups, such as phosphonamidate esters, phosphorothioate esters, phosphonate esters, and phosphon-bis-amidates; (2) carboxyl ester-forming groups, and (3) sulphur ester- forming groups, such as sulphonate, sulfate, and sulfinate. [0112] The phosphonate moieties of the compounds of the embodiments may or may not be prodrug moieties, i.e. they may or may not be susceptible to hydrolytic or enzymatic cleavage or modification. Certain phosphonate moieties are stable under most or nearly all metabolic conditions. For example, a dialkylphosphonate, where the alkyl groups are two or more carbons, may have appreciable stability in vivo due to a slow rate of hydrolysis. [0113] Within the context of phosphonate prodrug moieties, a large number of structurally-diverse prodrugs have been described for phosphonic acids (Freeman and Ross in Progress in Medicinal Chemistry 34: 112-147 (1997) and are included within the scope of the present embodiments. An exemplary embodiment of a phosphonate ester-forming group is the phenyl carbocycle in substructure A₃ having the formula:

wherein ml is 1, 2, 3, 4, 5, 6, 7 or 8, and the phenyl carbocycle is substituted with 0 to 3 R₂ groups. Also, in this embodiment, where Y₁ is O, a lactate ester is formed. Alternatively, where Y₁ is N(R₂), N(OR₂) or N(N(Rz)₂, then phosphonamidate esters result. R₁ may be H or C₁-C₁₂ alkyl. The corollary exemplary substructure A is

1 1 2 included in the embodiments with Y , R and R substituents.

[0114] In its ester-forming role, a protecting group typically is bound to any acidic group such as, by way of example and not limitation, a -CO2H or

-C(S)OH group, thereby resulting in -Cθ2R^x where R^x is defined herein. Also, R^x for example includes the enumerated ester groups of WO 95/07920, herein incorporated by reference in its entirety. [0115] Examples of protecting groups include, but are not limited to:

C3-C12 heterocycle (described above) or aryl. These aromatic groups optionally are polycyclic or monocyclic. Examples include phenyl, spiryl, 2- and 3-pyrrolyl, 2- and 3-thienyl, 2- and 4-imidazolyl, 2-, 4- and 5-oxazolyl, 3- and 4-isoxazolyl, 2-, 4- and 5- thiazolyl, 3-, 4- and 5-isothiazolyl, 3- and 4-pyrazolyl, 1-, 2-, 3- and 4-pyridinyl, and 1-, 2-, 4- and 5-pyrimidinyl,

C3-C12 heterocycle or aryl substituted with halo, R¹, R¹O-Ci-C^ alkylene, Q- C12 alkoxy, CN, NO2, OH, carboxy, carboxyester, thiol, thioester, C1-C12 haloalkyl (1-6 halogen atoms), C2-C12 alkenyl or C2-C12 alkynyl. Such groups include 2-, 3- and 4- alkoxyphenyl (C1-C12 alkyl), 2-, 3- and 4-methoxyphenyl, 2-, 3- and 4-ethoxyphenyl, 2,3-, 2,4-, 2,5-, 2,6-, 3,4- and 3,5-diethoxyphenyl, 2- and 3-carboethoxy-4- hydroxyphenyl, 2- and 3-ethoxy-4-hydroxyphenyl, 2- and 3-ethoxy-5-hydroxyphenyl, 2- and 3-ethoxy-6-hydroxyphenyl, 2-, 3- and 4-O-acetylphenyl, 2-, 3- and A- dimethylaminophenyl, 2-, 3- and 4-methylmercaptophenyl, 2-, 3- and 4-halophenyl (including 2-, 3- and 4-fluorophenyl and 2-, 3- and 4-chlorophenyl), 2,3-, 2,4-, 2,5-, 2,6-, 3,4- and 3,5-dimethylphenyl, 2,3-, 2,4-, 2,5-, 2,6-, 3,4- and 3,5-biscarboxyethylphenyl, 2,3-, 2,4-, 2,5-, 2,6-, 3,4- and 3,5-dimethoxyphenyl, 2,3-, 2,4-, 2,5-, 2,6-, 3,4- and 3,5- dihalophenyl (including 2,4-difluorophenyl and 3,5-difluorophenyl), 2-, 3- and 4- haloalkylphenyl (1 to 5 halogen atoms, C1-C12 alkyl including 4-trifluoromethylphenyl), 2-, 3- and 4-cyanophenyl, 2-, 3- and 4-nitrophenyl, 2-, 3- and 4-haloalkylbenzyl (1 to 5 halogen atoms, C1-C12 alkyl including 4-trifluoromethylbenzyl and 2-, 3- and 4- trichloromethylphenyl and 2-, 3- and 4-trichloromethylphenyl), 4-N-methylpiperidinyl, 3-N-methylpiperidinyl, 1-ethylpiperazinyl, benzyl, alkylsalicylphenyl (C1-C4 alkyl, including 2-, 3- and 4-ethylsalicylphenyl), 2-,3- and 4-acetylphenyl, 1,8- dihydroxynaphthyl (-C10H₆-OH) and aryloxy ethyl [C₆-C₉ aryl (including phenoxy ethyl)], 2,2'-dihydroxybiphenyl, 2-, 3- and 4-N,N-dialkylaminophenol, -C6H4CH2- N(CH3)2, trimethoxybenzyl, triethoxybenzyl, 2-alkyl pyridinyl (C1.4 alkyl);

; C4 - C8 esters of2- carboxyphenyl; and C1-C4 alkylene-C₃-C6 aryl (including benzyl, -CH2-pyrrolyl, -CH₂- thienyl, -CH2-imidazolyl, -CH2-oxazolyl, -CH2-isoxazolyl, -CH2-thiazolyl, -CH₂- isothiazolyl, -CH2-pyrazolyl, -CH2-pyridinyl and -CH2-pyrimidinyl) substituted in the aryl moiety by 3 to 5 halogen atoms or 1 to 2 atoms or groups selected from halogen, Ci- C 12 alkoxy (including methoxy and ethoxy), cyano, nitro, OH, Ci -C 12 haloalkyl (1 to 6 halogen atoms; including -CH2CCI3), C1-C12 alkyl (including methyl and ethyl), C2-C12 alkenyl or C2-C12 alkynyl; alkoxy ethyl [C1-C6 alkyl including -CH2-CH2-O-CH3 (methoxy ethyl)]; alkyl substituted by any of the groups set forth above for aryl, in particular OH or by 1 to 3 halo atoms (including -CH₃, -CH(CH3)2, -C(CH3)3, - CH₂CH₃, -(CH₂)₂CH₃, -(CH₂)₃CH₃, -(CH₂)₄CH₃, -(CH₂)₅CH₃,CH₂CH₂F, -CH₂CH₂Cl,

-CH₂CF₃, and

; -N-2-propylmorpholino, 2,3-dihydro-6- hydroxyindene, sesamol, catechol monoester, -CH₂-C(O)-N(R¹)₂, -CH₂-S(O)(R¹), - CH₂-S(O)₂(Rl), -CH₂-CH(OC(O)CH₂R¹)-CH₂(OC(O)CH₂Rl), cholesteryl, enolpyruvate (HOOC-C(=CH₂)-), glycerol; a 5 or 6 carbon monosaccharide, disaccharide or oligosaccharide (3 to 9 monosaccharide residues); triglycerides such as α-D-β-diglycerides (wherein the fatty acids composing glyceride lipids generally are naturally occurring saturated or unsaturated C_6-18, C_{6- 18} or C_6-10 fatty acids such as linoleic, lauric, myristic, palmitic, stearic, oleic, palmitoleic, linolenic and the like fatty acids) linked to acyl of the parental compounds herein through a glyceryl oxygen of the triglyceride; phospholipids linked to the carboxyl group through the phosphate of the phospholipid; phthalidyl (shown in Fig. 1 of Clayton et al., Antimicrob. Agents Chemo. (1974) 5(6):670-671, herein incorporated by reference in its entirety; cyclic carbonates such as (5-Rd-2-oxo-l,3-dioxolen-4-yl) methyl esters (Sakamoto et al., Chem. Pharm. Bull. (1984) 32(6)2241-2248, herein incorporated by reference in its entirety) where Rd is Ri, R4 or aryl; and

[0116] The hydroxyl groups of the compounds of the embodiments optionally are substituted with one of groups III, IV or V disclosed in WO 94/21604, herein incorporated by reference in its entirety, or with isopropyl. [0117] As further embodiments, Table A lists examples of protecting group ester moieties that for example can be bonded via oxygen to -C(O)O- and - P(O)(O-)2 groups. Several amidates also are shown, which are bound directly to -C(O)- or -P(O)2. Esters of structures 1-5, 8-10 and 16, 17, 19-22 are synthesized by reacting the compound herein having a free hydroxyl with the corresponding halide (chloride or acyl chloride and the like) and N ,N- dicyclohexyl-N-morpholine carboxamidine (or another base such as DBU, triethylamine, CSCO3, N,N-dimethylaniline and the like) in DMF (or other solvent such as acetonitrile or N-methylpyrrolidone). When the compound to be protected is a phosphonate, the esters of structures 5-7, 11, 12, 21, and 23-26 are synthesized by reaction of the alcohol or alkoxide salt (or the corresponding amines in the case of compounds such as 13, 14 and 15) with the monochlorophosphonate or dichlorophosphonate (or another activated phosphonate).

# - chiral center is (R), (S) or racemate.

[0118] Other esters that are suitable for use herein are described in EP 632048, herein incorporated by reference in its entirety. [0119] Protecting groups also includes "double ester" forming profunctionalities such as

-CH2OC(O)OCH3,

-CH2SCOCH3, -CH2θCON(CH3)2, or alkyl- or aryl- acyloxyalkyl groups of the structure -CH(R¹ or W⁵)O((CO)R³⁷) or -CH(R¹ or W⁵X(CO)OR³⁸) (linked to oxygen of the acidic group) wherein R³⁷ and R³⁸ are alkyl, aryl, or alkylaryl groups (see U.S. Patent No. 4,968,788, herein incorporated by reference in its entirety). Frequently R³⁷ and R³⁸ are bulky groups such as branched alkyl, ortho-substituted aryl, meta-substituted aryl, or combinations thereof, including normal, secondary, iso- and tertiary alkyls of 1-6 carbon atoms. An example is the pivaloyloxymethyl group. These are of particular use with prodrugs for oral administration. Examples of such useful protecting groups are alkylacyloxymethyl esters and their derivatives, including -CH(CH2CH2θCH3)OC(O)C(CH3)3,

-CH₂OC(O)CI₀HI₅, -CH₂OC(O)C(CH₃)₃, -CH(CH₂OCH₃)OC(O)C(CH₃)₃, -CH(CH(CH₃)₂)OC(O)C(CH₃)₃, -CH₂OC(O)CH₂CH(CH₃)₂, -CH₂OC(O)C₆Hi 1, -CH₂OC(O)C₆H₅, -CH₂OC(O)CI₀HI₅, -CH₂OC(O)CH₂CH₃, -CH₂OC(O)CH(CH₃)₂, -CH₂OC(O)C(CH₃)₃ and -CH₂OC(O)CH₂C₆H₅.

[0120] For prodrug purposes, the ester typically chosen is one heretofore used for antibiotic drugs, in particular the cyclic carbonates, double esters, or the phthalidyl, aryl or alkyl esters.

[0121] In some embodiments the protected acidic group is an ester of the acidic group and is the residue of a hydroxyl-containing functionality. In other embodiments, an amino compound is used to protect the acid functionality. The residues of suitable hydroxyl or amino-containing functionalities are set forth above or are found in WO 95/07920. Of particular interest are the residues of amino acids, amino acid esters, polypeptides, or aryl alcohols. Typical amino acid, polypeptide and carboxyl-esterified amino acid residues are described on pages 11-18 and related text of WO 95/07920 as groups Ll or L2. WO 95/07920 expressly teaches the amidates of phosphonic acids, but it will be understood that such amidates are formed with any of the acid groups set forth herein and the amino acid residues set forth in WO 95/07920.

[0122] Typical esters for protecting acidic functionalities are also described in WO 95/07920, again understanding that the same esters can be formed with the acidic groups herein as with the phosphonate of the '920 publication. Typical ester groups are defined at least on WO 95/07920 pages 89-93 (under R^ 1 or R35), the table on page 105, and pages 21-23 (as R). Of particular interest are esters of unsubstituted aryl such as phenyl or arylalkyl such benzyl, or hydroxy-, halo-, alkoxy-, carboxy- and/or alkylestercarboxy-substituted aryl or alkylaryl, especially phenyl, ortho-ethoxyphenyl, or C1-C4 alkylestercarboxyphenyl (salicylate C1-C12 alkylesters).

[0123] The protected acidic groups, particularly when using the esters or amides of WO 95/07920, are useful as prodrugs for oral administration. However, it is not essential that the acidic group be protected in order for the compounds of the embodiments to be effectively administered by the oral route. When the compounds of the embodiments having protected groups, in particular amino acid amidates or substituted and unsubstituted aryl esters are administered systemically or orally they are capable of hydrolytic cleavage in vivo to yield the free acid.

[0124] One or more of the acidic hydroxyls are protected. If more than one acidic hydroxyl is protected then the same or a different protecting group is employed, e.g., the esters may be different or the same, or a mixed amidate and ester may be used.

[0125] Typical hydroxy protecting groups described in Greene (pages 14-118) include substituted methyl and alkyl ethers, substituted benzyl ethers, silyl ethers, esters including sulfonic acid esters, and carbonates. For example:

• Ethers (methyl, t-butyl, allyl);

• Substituted Methyl Ethers (Methoxymethyl, Methylthiomethyl, t-Butylthiomethyl, (Phenyldimethylsilyl)methoxymethyl, Benzyloxymethyl, p- Methoxybenzyloxymethyl, (4-Methoxyphenoxy)methyl, Guaiacolniethyl, t- Butoxymethyl, 4-Pentenyloxymethyl, Siloxymethyl, 2-Methoxyethoxymethyl, 2,2,2-

Trichloroethoxymethyl, Bis(2-chloroethoxy)methyl, 2-(Trimethylsilyl)ethoxymethyl, Tetrahydropyranyl, 3-Bromotetrahydropyranyl, Tetrahydropthiopyranyl, 1- Methoxycyclohexyl, 4-Methoxytetrahydropyranyl, 4-Methoxytetrahydrothiopyranyl, 4-Methoxytetrahydropthiopyranyl S,S-Dioxido, 1 -[(2-Chloro-4-methyl)phenyl]-4- methoxypiperidin-4-yl, l,4-Dioxan-2-yl, Tetrahydrofuranyl, Tetrahydrothiofuranyl, 2,3,3a,4,5,6,7,7a-Octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)); Substituted Ethyl Ethers (1-Ethoxy ethyl, l-(2-Chloroethoxy)ethyl, 1-Methyl-l- methoxyethyl, 1 -Methyl- 1 -benzyloxyethyl, 1 -Methyl- 1 -benzyloxy-2-fluoroethyl, 2,2,2-Trichloroethyl, 2-Trimethylsilylethyl, 2-(Phenylselenyl)ethyl, p-Chlorophenyl,p-Methoxyphenyl, 2,4-Dinitrophenyl, Benzyl); Substituted Benzyl Ethers (p-Methoxybenzyl, 3,4-Dimethoxybenzyl, o-Nitrobenzyl, p-Nitrobenzyl,p-Halobenzyl, 2,6-Dichlorobenzyl, p-Cyanobenzyl, p-Phenylbenzyl, 2- and 4-Picolyl, 3-Methyl-2-picolyl N-Oxido, Diphenylmethyl, p,p'- Dinitrobenzhydryl, 5-Dibenzosuberyl, Triphenylmethyl, α-Naphthyldiphenylmethyl, p-methoxyphenyldiphenylmethyl, Di(p-methoxyphenyl)phenylmethyl, Tri(p- methoxyphenyl)methyl, 4-(4'-Bromophenacyloxy)phenyldiphenylmethyl, 4,4',4"- Tris(4,5-dichlorophthalimidophenyl)methyl, 4,4',4"-

Tris(levulinoyloxyphenyl)methyl, 4,4',4"-Tris(benzoyloxyphenyl)methyl, 3- (Imidazol- 1 -ylmethyl)bis(4',4"-dimethoxyphenyl)methyl, 1 , 1 -Bis(4-methoxyphenyl)- l'-pyrenylmethyl, 9-Anthryl, 9-(9-Phenyl)xanthenyl, 9-(9-Phenyl-10-oxo)anthryl, l,3-Benzodithiolan-2-yl, Benzisothiazolyl S,S-Dioxido); Silyl Ethers (Trimethylsilyl, Triethylsilyl, Triisopropylsilyl, Dimethylisopropylsilyl, Diethylisopropylsilyl, Dimethylthexylsilyl, t-Butyldimethylsilyl, t- Butyldiphenylsilyl, Tribenzylsilyl, Tri-p-xylylsilyl, Triphenylsilyl, Diphenylmethylsilyl, t-Butylraethoxyphenylsilyl); Esters (Formate, Benzoylformate, Acetate, Chloroacetate, Dichloroacetate, Trichloroacetate, Trifluoroacetate, Methoxyacetate, Triphenylmethoxyacetate, Phenoxyacetate,p-Chlorophenoxyacetate,p-poly-Phenylacetate, 3-Phenylpropionate, 4-Oxopentanoate (Levulinate), 4,4-(Ethylenedithio)pentanoate, Pivaloate, Adamantoate, Crotonate, 4-Methoxycrotonate, Benzoate,p-Phenylbenzoate, 2,4,6- Trimethylbenzoate (Mesitoate)); Carbonates (Methyl, 9-Fluorenylmethyl, Ethyl, 2,2,2-Trichloroethyl, 2- (Trimethylsilyl)ethyl, 2-(Phenylsulfonyl)ethyl, 2-(Triphenylphosphonio)ethyl, Isobutyl, Vinyl, AHyI,p-Nitrophenyl, Benzyl,p-Methoxybenzyl, 3,4- Dimethoxybenzyl, o-Nitrobenzyl, p-Nitrobenzyl, S-Benzyl Thiocarbonate, 4-Ethoxy- 1-naphthyl, Methyl Dithiocarbonate);

• Groups With Assisted Cleavage (2-Iodobenzoate, 4-Azidobutyrate, 4-Nitro-4- methylpentanoate, ø-(Dibromomethyl)benzoate, 2-Formylbenzenesulfonate, 2- (Methylthiomethoxy)ethyl Carbonate, 4-(Methylthiomethoxy)butyrate, 2- (Methylthiomethoxymethyl)benzoate); Miscellaneous Esters (2,6-Dichloro-4- methylphenoxyacetate, 2,6-Dichloro-4-(l, 1,3,3 tetramethylbutyl)phenoxyacetate, 2,4-Bis( 1 , 1 -dirnethylpropyl)phenoxyacetate, Chlorodiphenylacetate, Isobutyrate, Monosuccinate, (E)-2-Methyl-2-butenoate (Tigloate), o-(Methoxycarbonyl)benzoate, p-poly-Benzoate, α-Naphthoate, Nitrate, Alkyl N, N, N', N'- Tetramethylphosphorodiamidate, N-Phenylcarbamate, Borate, Dimethylphosphinothioyl, 2,4-Dinitrophenylsulfenate); and

• Sulfonates (Sulfate, Methanesulfonate (Mesylate), Benzylsulfonate, Tosylate). [0126] Typical 1,2-diol protecting groups (thus, generally where two OH groups are taken together with the protecting functionality) are described in Greene at pages 118-142 and include Cyclic Acetals and Ketals (Methylene, Ethylidene, 1-t-Butylethylidene, 1-Phenylethylidene, (4- Methoxyphenyl)ethylidene, 2,2,2-Trichloroethylidene, Acetonide (Isopropylidene), Cyclopentylidene, Cyclohexylidene, Cycloheptylidene, Benzylidene, p-Methoxybenzylidene, 2,4-Dimethoxybenzylidene, 3,4- Dimethoxybenzylidene, 2-Nitrobenzylidene); Cyclic Ortho Esters (Methoxymethylene, Ethoxymethylene, Dimethoxymethylene, 1- Methoxyethylidene, 1-Ethoxyethylidine, 1,2-Dimethoxyethylidene, α- Methoxybenzylidene, 1-(N,N-Dimethylamino)ethylidene Derivative, α -(N,N- Dimethylamino)benzylidene Derivative, 2-Oxacyclopentylidene); Silyl Derivatives (Di-t-butylsilylene Group, 1 ,3 -(1 ,1,3,3 -

Tetraisopropyldisiloxanylidene), and Tetra-t-butoxydisiloxane- 1 ,3 -diylidene), Cyclic Carbonates, Cyclic Boronates, Ethyl Boronate and Phenyl Boronate. [0127] More typically, 1,2-diol protecting groups include those shown in Table B, still more typically, epoxides, acetonides, cyclic ketals and aryl acetals.

Table B

wherein R.⁹ is C1-C6 alkyl.

Amino protecting groups

[0128] Another set of protecting groups include any of the typical amino protecting groups described by Greene at pages 315-385. They include:

• Carbamates: (methyl and ethyl, 9-fluorenylmethyl, 9(2-sulfo)fluorenylmethyl, 9-(2,7- dibromo)fluorenylmethyl, 2,7-di-t-butyl- [9-(l 0, 10-dioxo- 10,10.10,10- tetrahydrothioxanthyl)]methyl, 4-methoxyphenacyl);

• Substituted Ethyl: (2,2,2-trichoroethyl, 2-trimethylsilylethyl, 2-ρhenylethyl, 1-(1- adamantyl)- 1 -methylethyl, 1 , 1 -dimethyl-2-haloethyl, 1 , 1 -dimethyl-2,2-dibrornoethyl, 1 , 1 -dimethyl-2,2,2-trichloroethyl, 1 -methyl- 1 -(4-biphenylyl)ethyl, 1 -(3 ,5-di-t- butylphenyl)-l -methylethyl, 2-(2'- and 4'-pyridyl)ethyl, 2-(N,N- dicyclohexylcarboxamido)ethyl, t-butyl, 1-adamantyl, vinyl, allyl, 1-isopropylallyl, cinnamyl, 4-nitrocinnamyl, 8-quinolyl, N-hydroxypiperidinyl, alkyldithio, benzyl, p- methoxybenzyl, p-nitrobenzyl, p-bromobenzyl, p-chlorobenzyl, 2,4-dichlorobenzyl, 4-methylsulfinylbenzyl, 9-anthrylmethyl, diphenylmethyl);

• Groups With Assisted Cleavage: (2-methylthioethyl, 2-methylsulfonylethyl, 2-(p- toluenesulfonyl)ethyl, [2-(l,3-dithianyl)]methyl, 4-methylthiophenyl, 2,4- dimethylthiophenyl, 2-phosphonioethyl, 2-triphenylphosphonioisopropyl, 1,1- dimethyl-2-cyanoethyl, m-choro-p-acyloxybenzyl, p-(dihydroxyboryl)benzyl, 5- benzisoxazolylmethyl, 2-(trifluoromethyl)-6-chromonylmethyl);

• Groups Capable of Photolytic Cleavage: (m-nitrophenyl, 3,5-dimethoxybenzyl, o- nitrobenzyl, 3,4-dimethoxy-6-nitrobenzyl, phenyl(ø-nitrophenyl)methyl); Urea-Type Derivatives (phenothiazinyl-(lθ)-carbonyl, N'-p-toluenesulfonylaminocarbonyl, N- phenylaminothiocarbonyl);

• Miscellaneous Carbamates: (t-amyl, S-benzyl thiocarbamate,p-cyanobenzyl, cyclobutyl, cyclohexyl, cyclopentyl, cyclopropylmethyl,p-decyloxybenzyl, diisopropylmethyl, 2,2-dimethoxycarbonylvinyl, o-(N,N- dimethylcarboxamido)benzyl, 1 , 1 -dimethyl-3 -(N, N-dimethylcarboxamido)propyl, 1,1-dimethylpropynyl, di(2-pyridyl)methyl, 2-furanylmethyl, 2-Iodoethyl, Isobornyl, Isobutyl, Isonicotinyl,p-(p'-Methoxyphenylazo)benzyl, 1-methylcyclobutyl, 1- methylcyclohexyl, 1 -methyl- 1 -cyclopropylmethyl, 1 -methyl- 1 -(3,5- dimethoxyphenyl)ethyl, 1 -methyl- 1 -(p-phenylazophenyl)ethyl, 1 -methyl- 1 - phenylethyl, 1 -methyl- l-(4-pyridyl)ethyl, phenyl,p-(phenylazo)benzyl, 2,4,6-tri-t- butylphenyl, 4-(trimethylammonium)benzyl, 2,4,6-trimethylbenzyl);

• Amides: (N-formyl, N-acetyl, N-choroacetyl, N-trichoroacetyl, N-trifluoroacetyl, N- phenylacetyl, N-3-phenylpropionyl, N-picolinoyl, N-3-pyridylcarboxamide, N- benzoylphenylalanyl, N-benzoyl, N-p-phenylbenzoyl);

• Amides With Assisted Cleavage: (N-o-nitrophenylacetyl, N-o-nitrophenoxyacetyl, N- acetoacetyl, (N'-dithiobenzyloxycarbonylamino)acetyl, N-3-(p- hydroxyphenyl)propionyl, N-3-(o-nitrophenyl)propionyl, N-2-methyl-2-(o- nitrophenoxy)propionyl, N-2-methyl-2-(o-phenylazophenoxy)propionyl, N-4- chlorobutyryl, N-3-methyl-3-nitrobutyryl, N-o-nitrocinnamoyl, N-acetylmethionine, N-o-nitrobenzpyl, N-o-(benzoyloxymethyl)benzoyl, 4,5-diphenyl-3-oxazolin-2-one);

• Cyclic Imide Derivatives: (N-phthalimide, N-dithiasuccinoyl, N-2,3- diphenylmaleoyl, N-2,5-dimethylpyrrolyl, N- 1,1, 4,4- tetramethyldisilylazacyclopentane adduct, 5-substituted l,3-dimethyl-l,3,5- triazacyclohexan-2-one, 5-substituted l,3-dibenzyl-l,3-5-triazacyclohexan-2-one, 1- substituted 3,5-dinitro-4-pyridonyl);

• N-Alkyl and N-Aryl Amines: (N-methyl, N-allyl, N-[2-(trimethylsilyl)ethoxy]methyl, N-3 -acetoxypropyl, N-(I -isopropyl-4-nitro-2-oxo-3 -pyrrolin-3 -yl), Quaternary Ammonium Salts, N-benzyl, N-di(4-methoxyphenyl)methyl, N-5-dibenzosuberyl, N- triphenylmethyl, N-(4-methoxyphenyl)diphenylmethyl, N-9-phenylfluorenyl, N-2,7- dichloro-9-fluorenylmethylene, N-ferrocenylmethyl, N-2-picolylamine N-oxide);

• Imine Derivatives : (N-1,1 -dimethylthiomethylene, N-benzylidene, N-p- methoxybenylidene, N-diphenylmethylene, N-[(2-pyridyl)mesityl]methylene, N,(N ,N-dimethylaminomethylene, N,N -isopropylidene, N-p-nitrobenzylidene, N- salicylidene, N-5-chlorosalicylidene, N-(5-chloro-2- hydroxyphenyl)phenylmethylene, N-cy clohexylidene) ;

• Enamine Derivatives: (N-(5,5-dimethyl-3-oxo-l-cyclohexenyl));

• N~Metal Derivatives (N-borane derivatives, N-diphenylborinic acid derivatives, N- [phenyl(pentacarbonylchromium- or -tungsten)] carbenyl, N-copper or N-zinc chelate);

• Ν-Ν Derivatives: (N-nitro, N-nitroso, N-oxide);

• N-P Derivatives: (N-diphenylphosphinyl, N-dimethylthiophosphinyl, N- diphenylthiophosphinyl, N-dialkyl phosphoryl, N-dibenzyl phosphoryl, N-diphenyl phosphoryl);

• N-Si Derivatives, N-S Derivatives, and N-Sulfenyl Derivatives: (N-benzenesulfenyl, N-o-nitrobenzenesulfenyl, N-2,4-dinitrobenzenesulfenyl, N- pentachlorobenzenesulfenyl, N-2-nitro-4-methoxybenzenesulfenyl, N- triphenylmethylsulfenyl, N-3-nitropyridinesulfenyl); and N-sulfonyl Derivatives (N- p-toluenesulfonyl, N-benzenesulfonyl, N-2,3 ,6-trimethyl-4-methoxybenzenesulfonyl, N-2,4,6-trimethoxybenzeaesulfonyl, N-2,6-dimethyl-4-methoxybenzenesulfonyl, N- pentamethylbenzenesulfonyl, N-2,3 ,5 ,6,-tetramethyl-4-methoxybenzenesulfonyl, N- 4-methoxybenzenesulfonyl, N-2,4,6-trimethylbenzenesulfonyl, N-2,6-dimethoxy-4- methylbenzenesulfonyl, N-2,2,5,7,8-pentamethylchroman-6-sulfonyl, N- methanesulfonyl, N-β-trimethylsilyethanesulfonyl, N-9-anthracenesulfonyl, N-4-

(4' , 8 '-dimethoxynaphthy lmethyl)benzenesulfonyl, N-benzylsulfony 1, N- trifluoromethylsulfonyl, N-phenacylsulfonyl) .

[0129] Protected amino groups include carbamates, amides and amidines, e.g. -NHC(O)OR¹, -NHC(O)R¹ or -N=CR¹N(R¹)₂. Another protecting group, also useful as a prodrug for amino or -NH(R⁵), is:

See for example Alexander, J. et al (1996) J. Med. Chem. 39:480-486, herein incorporated by reference in its entirety.

Amino acid and polypeptide protecting group and conjugates [0130] An amino acid or polypeptide protecting group of a compound of the embodiments has the structure R¹⁵NHCH(R¹⁶)C(O)-, where R¹⁵ is H, an amino acid or polypeptide residue, or R⁵, and R is defined below. [0131] R¹⁶ is lower alkyl or lower alkyl (C₁-C₆) substituted with amino, carboxyl, amide, carboxyl ester, hydroxyl, C₆-C₇ aryl, guanidinyl, imidazolyl, indolyl, sulfhydryl, sulfoxide, and/or alkylphosphate. R¹⁶ also is taken together with the amino acid α-N to form a proline residue (R¹⁶ = -CH₂)3-). However, R¹⁶ is generally the side group of a naturally-occurring amino acid such as H, -CH3, - CH(CH₃)₂, -CH₂-CH(CH₃)₂, -CHCH₃-CH₂-CH₃, -CH₂-C₆H₅, -CH₂CH₂-S-CH₃, -CH₂OH, -CH(OH)-CH₃, -CH₂-SH, -CH₂-C₆H₄OH, -CH₂-CO-NH₂, -CH₂-CH₂- CO-NH₂, -CH₂-COOH, -CH₂-CH₂-COOH, -(CH₂)₄-NH₂ and -(CH₂)₃-NH- C(NH₂)-NH₂. R¹⁶ also includes l-guanidinoprop-3-yl, benzyl, 4-hydroxybenzyl, imidazol-4-yl, indol-3-yl, methoxyphenyl and ethoxyphenyl. [0132] Another set of protecting groups include the residue of an amino- containing compound, in particular an amino acid, a polypeptide, a protecting group, -NHSO2R NHC(O)R, -N(R)2, NH2 or -NH(R)(H), whereby for example a carboxylic acid is reacted, i.e. coupled, with the amine to form an amide, as in C(O)NR₂. A phosphonic acid may be reacted with the amine to form a phosphonamidate, as in -P(O)(OR)(NR₂).

[0133] Amino acids have the structure R¹⁷C(O)CH(R¹⁶)NH-, where R¹⁷ is -OH, -OR, an amino acid or a polypeptide residue. Amino acids are low molecular weight compounds, on the order of less than about 1000 MW and which contain at least one amino or imino group and at least one carboxyl group. Generally the amino acids will be found in nature, i.e., can be detected in biological material such as bacteria or other microbes, plants, animals or man. Suitable amino acids typically are alpha amino acids, i.e. compounds characterized by one amino or imino nitrogen atom separated from the carbon atom of one carboxyl group by a single substituted or unsubstituted alpha carbon atom. Of particular interest are hydrophobic residues such as mono-or di-alkyl or aryl amino acids, cycloalkylamino acids and the like. These residues contribute to cell permeability by increasing the partition coefficient of the parental drug. Typically, the residue does not contain a sulfhydryl or guanidino substituent. [0134] Naturally-occurring amino acid residues are those residues found naturally in plants, animals or microbes, especially proteins thereof. Polypeptides most typically will be substantially composed of such naturally-occurring amino acid residues. These amino acids are glycine, alanine, valine, leucine, isoleucine, serine, threonine, cysteine, methionine, glutamic acid, aspartic acid, lysine, hydroxylysine, arginine, histidine, phenylalanine, tyrosine, tryptophan, proline, asparagine, glutamine and hydroxyproline. Additionally, unnatural amino acids, for example, valanine, phenylglycine and homoarginine are also included. Commonly encountered amino acids that are not gene-encoded may also be used in the present embodiments. All of the amino acids used in the present embodiments may be either the D- or L- optical isomer. In addition, other peptidomimetics are also useful in the present embodiments. For a general review, see Spatola, A. F., in Chemistry and Biochemistry of Amino Acids, Peptides and Proteins, B. Weinstein, eds., Marcel Dekker, New York, p. 267 (1983).

[0135] When protecting groups are single amino acid residues or polypeptides they optionally are substituted at R³ of substituents A¹, A² or A³ in Formula I, or substituted at R₃ of substituents A₁, A₂ or A₃ in Formula II. These conjugates are generally produced by forming an amide bond between a carboxyl group of the amino acid (or C-terminal amino acid of a polypeptide for example). Alternatively, conjugates are formed between R³ (Formula I) or R₃ (Formula II) and an amino group of an amino acid or polypeptide. Generally, only one of any site in the scaffold drug-like compound is amidated with an amino acid as described herein, although it is within the scope of the embodiments to introduce amino acids at more than one permitted site. Usually, a carboxyl group of R³ is amidated with an amino acid. In general, the α-amino or α-carboxyl group of the amino acid or the terminal amino or carboxyl group of a polypeptide are bonded to the scaffold, parental functionalities. Carboxyl or amino groups in the amino acid side chains generally may be used to form the amide bonds with the parental compound or these groups may need to be protected during synthesis of the conjugates as described further below.

[0136] With respect to the carboxyl-containing side chains of amino acids or polypeptides it will be understood that the carboxyl group optionally will be blocked, e.g. by R¹, esterified with R⁵ or amidated. Similarly, the amino side chains R¹⁶ optionally will be blocked with R¹ or substituted with R⁵. [0137] Such ester or amide bonds with side chain amino or carboxyl groups, like the esters or amides with the parental molecule, optionally are hydrolyzable in vivo or in vitro under acidic (pH <3) or basic (pH >10) conditions. Alternatively, they are substantially stable in the gastrointestinal tract of humans but are hydrolyzed enzymatically in blood or in intracellular environments. The esters or amino acid or polypeptide amidates also are useful as intermediates for the preparation of the parental molecule containing free amino or carboxyl groups. The free acid or base of the parental compound, for example, is readily formed from the esters or amino acid or polypeptide conjugates of the embodiments by conventional hydrolysis procedures.

[0138] When an amino acid residue contains one or more chiral centers, any of the D, L, meso, threo or erythro (as appropriate) racemates, scalemates or mixtures thereof may be used. In general, if the intermediates are to be hydrolyzed non-enzymatically (as would be the case where the amides are used as chemical intermediates for the free acids or free amines), D isomers are useful. On the other hand, L isomers are more versatile since they can be susceptible to both non-enzymatic and enzymatic hydrolysis, and are more efficiently transported by amino acid or dipeptidyl transport systems in the gastrointestinal tract.

[0139] Examples of suitable amino acids whose residues are represented by R^x or R^y include the following:

Glycine;

Aminopolycarboxylic acids, e.g., aspartic acid, β-hydroxyaspartic acid, glutamic acid, β -hydroxyglutamic acid, β-methylaspartic acid, β-methylglutamic acid, β, β- dimethylaspartic acid, γ-hydroxygmtamic acid, β, γ-dihydroxyglutamic acid, β - phenylglutamic acid, γ-methyleneglutamic acid, 3-aminoadipic acid, 2-aminopimelic acid, 2-aminosuberic acid and 2-aminosebacic acid; Amino acid amides such as glutamine and asparagine;

Polyamino- or polybasic-monocarboxylic acids such as arginine, lysine, β - aminoalanine, γ -aminobutyrine, ornithine, citruline, homoarginine, homocitrulline, hydroxylysine, allohydroxylsine and diaminobutyric acid;

Other basic amino acid residues such as histidine;

Diaminodicarboxylic acids such as α, α'-diaminosuccinic acid, α, α'~ diaminoglutaric acid, α, α'-diaminoadipic acid, α, α'-diaminopimelic acid, α, α'-diamino- β-hydroxypimelic acid, α, α'-diaminosuberic acid, α, α'-diaminoazelaic acid, and α, α¹- diaminosebacic acid;

Imino acids such as proline, hydroxyproline, allohydroxyproline, γ- methylproline, pipecolic acid, 5-hydroxypipecolic acid, and azetidine-2-carboxylic acid;

A mono- or di-alkyl (typically C₁-C₈ branched or normal) amino acid such as alanine, valine, leucine, allylglycine, butyrine, norvaline, norleucine, heptyline, α- methylserine, α-amino-α-methyl-γ-hydroxyvaleric acid, α-amino- α-methyl-δ- hydroxyvaleric acid, α-amino- α-methyl-ε-hydroxycaproic acid, isovaline, α- methylglutamic acid, α-aminoisobutyric acid, α-aminodiethylacetic acid, α- aminodiisopropylacetic acid, α-aminodi-n-propylacetic acid, α-aminodiisobutylacetic acid, α-aminodi-n-butylacetic acid, α-aminoethylisopropylacetic acid, α-amino-n- propylacetic acid, α-aminodiisoamyacetic acid, α-methylaspartic acid, α-methylglutamic acid, 1-aminocyclopropane-l-carboxylic acid, isoleucine, alloisoleucine, tert-leucine, β- methyltryptophan and α-amino- β-ethyl-β-phenylpropionic acid; β-phenylserinyl;

Aliphatic α-amino-β-hydroxy acids such as serine, β-hydroxyleucine, β- hydroxynorleucine, β -hydroxynorvaline, and α-amino-β-hydroxystearic acid; α-Amino, α-, γ-, δ- or ε-hydroxy acids such as homoserine, δ -hydroxynorvaline, γ-hydroxynorvaline and ε-hydroxynorleucine residues; canavine and canaline; γ - hydroxyornithine;

2-hexosaminic acids such as D-glucosaminic acid or D-galactosaminic acid; α-Amino-β-thiols such as penicillamine, β-thiolnorvaline or β-thiolbutyrine;

Other sulfur containing amino acid residues including cysteine; homocystine, β- phenylmethionine, methionine, S-allyl-L-cysteine sulfoxide, 2-thiolhistidine, cystathionine, and thiol ethers of cysteine or homocysteine;

Phenylalanine, tryptophan and ring-substituted α-amino acids such as the phenyl- or cyclohexylamino acids α-aminophenylacetic acid, α-aminocyclohexylacetic acid and α-amino-β-cyclohexylpropionic acid; phenylalanine analogues and derivatives comprising aryl, lower alkyl, hydroxy, guanidino, oxyalkylether, nitro, sulfur or halo- substituted phenyl (e.g., tyrosine, methyltyrosine and o-chloro-, p-chloro-, 3,4-dichloro, O-, m- or/>-methyl-, 2,4,6-trimethyl-, 2-ethoxy-5-nitro-, 2-hydroxy-5-nitro- and p-nitro- phenylalanine); furyl-, thienyl-, pyridyl-, pyrimidinyl-, purinyl- or naphthyl-alanines; and tryptophan analogues and derivatives including kynurenine, 3-hydroxykynurenine, 2- hydroxytryptophan and 4-carboxytryptophan; α- Amino substituted amino acids including sarcosine (N-methylglycine), N- benzylglycine, N-methylalanine, N-benzylalanine, N-methylphenylalanine, N- benzylphenylalanine, N-methylvaline and N-benzylvaline; and α-Hydroxy and substituted α -hydroxy amino acids including serine, threonine, allothreonine, phosphoserine and phosphothreonine.

[0140] Polypeptides are polymers of amino acids in which a carboxyl group of one amino acid monomer is bonded to an amino or imino group of the next amino acid monomer by an amide bond. Polypeptides include dipeptides, low molecular weight polypeptides (about 1500-5000 MW) and proteins. Proteins optionally contain 3, 5, 10, 50, 75, 100 or more residues, and suitably are substantially sequence-homologous with human, animal, plant or microbial proteins. They include enzymes (e.g., hydrogen peroxidase) as well as immunogens such as KLH, or antibodies or proteins of any type against which one wishes to raise an immune response. The nature and identity of the polypeptide may vary widely.

[0141] The polypeptide amidates are useful as immunogens in raising antibodies against either the polypeptide (if it is not immunogenic in the animal to which it is administered) or against the epitopes on the remainder of the compound of the embodiments.

[0142] Antibodies capable of binding to the parental non-peptidyl compound are used to separate the parental compound from mixtures, for example in diagnosis or manufacturing of the parental compound. The conjugates of parental compound and polypeptide generally are more immunogenic than the polypeptides in closely homologous animals, and therefore make the polypeptide more immunogenic for facilitating raising antibodies against it. Accordingly, the polypeptide or protein may be immunogenic in an animal typically used to raise antibodies, e.g., rabbit, mouse, horse, or rat. The polypeptide optionally contains a peptidolytic enzyme cleavage site at the peptide bond between the first and second residues adjacent to the acidic heteroatom. Such cleavage sites are flanked by enzymatic recognition structures, e.g. a particular sequence of residues recognized by a peptidolytic enzyme.

[0143] Peptidolytic enzymes for cleaving the polypeptide conjugates of the embodiments are well known, and in particular include carboxypeptidases, which digest polypeptides by removing C-terminal residues, and are specific in many instances for particular C-terminal sequences. Such enzymes and their substrate requirements in general are well known. For example, a dipeptide (having a given pair of residues and a free carboxyl terminus) is covalently bonded through its α-amino group to the phosphorus or carbon atoms of the compounds herein. In certain embodiments, a phosphonate group substituted with an amino acid or peptide will be cleaved by the appropriate peptidolytic enzyme, leaving the carboxyl of the proximal amino acid residue to autocatalytically cleave the phosphonoamidate bond.

[0144] Suitable dipeptidyl groups (designated by their single letter code) are AA, AR, AN, AD, AC, AE, AQ, AG, AH, AI, AL, AK, AM, AF, AP, AS, AT, AW, AY, AV, RA, RR, RN, RD, RC, RE, RQ, RG, RH, RI, RL, RK, RM, RF, RP, RS, RT, RW, RY, RV, NA, NR, NN, ND, NC, NE, NQ, NG, NH, NI, NL, NK, NM, NF, NP, NS, NT, NW, NY, NV, DA, DR, DN, DD, DC, DE, DQ, DG, DH, DI, DL, DK, DM, DF, DP, DS, DT, DW, DY, DV, CA, CR, CN, CD, CC, CE, CQ, CG, CH, CI, CL, CK, CM, CF, CP, CS, CT, CW, CY, CV, EA, ER, EN, ED, EC, EE, EQ, EG, EH, EI, EL, EK, EM, EF, EP, ES, ET, EW, EY, EV, QA, QR, QN, QD, QC, QE, QQ, QG, QH, QI, QL, QK, QM, QF, QP, QS, QT, QW, QY, QV, GA, GR, GN, GD, GC, GE, GQ, GG, GH, GI, GL, GK, GM, GF, GP, GS, GT, GW, GY, GV, HA, HR, HN, HD, HC, HE, HQ, HG, HH, HI, HL, HK, HM, HF, HP, HS, HT, HW, HY, HV, IA, IR, IN, ID, IC, IE, IQ, IG, IH, II, IL, IK, IM, IF, IP, IS, IT, IW, IY, IV, LA, LR, LN, LD, LC, LE, LQ, LG, LH, LI, LL, LK, LM, LF, LP, LS, LT, LW, LY, LV, KA, KR, KN, KD, KC, KE, KQ, KG, KH, KI, KL, KK, KM, KF, KP, KS, KT, KW, KY, KV, MA, MR, MN, MD, MC, ME, MQ, MG, MH, MI, ML, MK, MM, MF, MP, MS, MT, MW, MY, MV, FA, FR, FN, FD, FC, FE, FQ, FG, FH, FI, FL, FK, FM, FF, FP, FS, FT, FW, FY, FV, PA, PR, PN, PD, PC, PE, PQ, PG, PH, PI, PL, PK, PM, PF, PP, PS, PT, PW, PY, PV, SA, SR, SN, SD, SC, SE, SQ, SG, SH, SI, SL, SK, SM, SF, SP, SS, ST, SW, SY, SV, TA, TR, TN, TD, TC, TE, TQ, TG, TH, TI, TL, TK, TM, TF, TP, TS, TT, TW, TY, TV, WA, WR, WN, WD, WC, WE, WQ, WG, WH, WI, WL, WK, WM, WF, WP, WS, WT, WW, WY, WV, YA, YR, YN, YD, YC, YE, YQ, YG, YH, YI, YL, YK, YM, YF, YP, YS, YT, YW, YY, YV, VA, VR, VN, VD, VC, VE, VQ, VG, VH, VI, VL, VK, VM, VF, VP, VS, VT, VW, VY and VV. [0145] Tripeptide residues are also useful as protecting groups. When a phosphonate is to be protected, the sequence -X⁴-pro-X⁵- (where X⁴ is any amino acid residue and X⁵ is an amino acid residue, a carboxyl ester of proline, or hydrogen) will be cleaved by luminal carboxypeptidase to yield X⁴ with a free carboxyl, which in turn is expected to autocatalytically cleave the phosphonoamidate bond. The carboxy group of X⁵ optionally is esterified with benzyl.

[0146] Dipeptide or tripeptide species can be selected on the basis of known transport properties and/or susceptibility to peptidases that can affect transport to intestinal mucosal or other cell types. Dipeptides and tripeptides lacking an α- amino group are transport substrates for the peptide transporter found in brush border membrane of intestinal mucosal cells (Bai, J.P.F., (1992) Pharm Res. 9:969-978. Transport competent peptides can thus be used to enhance bioavailability of the amidate compounds. Di- or tripeptides having one or more amino acids in the D configuration may be compatible with peptide transport. Amino acids in the D configuration can be used to reduce the susceptibility of a di- or tripeptide to hydrolysis by proteases common to the brush border such as aminopeptidase N. In addition, di- or tripeptides alternatively are selected on the basis of their relative resistance to hydrolysis by proteases found in the lumen of the intestine. For example, tripeptides or polypeptides lacking asp and/or glu are poor substrates for aminopeptidase A, di- or tripeptides lacking amino acid residues on the N-terminal side of hydrophobic amino acids (leu, tyr, phe, val, trp) are poor substrates for endopeptidase, and peptides lacking a pro residue at the penultimate position at a free carboxyl terminus are poor substrates for carboxypeptidase P. Similar considerations can also be applied to the selection of peptides that are either relatively resistant or relatively susceptible to hydrolysis by cytosolic, renal, hepatic, serum or other peptidases. Such poorly cleaved polypeptide amidates are immunogens or are useful for bonding to proteins in order to prepare immunogens.

Recursive Substituents

[0147] Selected substituents within the compounds of the embodiments are present to a recursive degree. In this context, "recursive substituent" means that a substituent may recite another instance of itself. Because of the recursive nature of such substituents, theoretically, a large number of compounds may be present in any given embodiment. For example, R^x contains a R^y substituent. R^y can be R², which in turn can be R³. IfR³ is selected to be R^3c, then a second instance of R^x can be selected. One of ordinary skill in the art of medicinal chemistry understands that the total number of such substituents is reasonably limited by the desired properties of the compound intended. Such properties include, by of example and not limitation, physical properties such as molecular weight, solubility or log P, application properties such as activity against the intended target, and practical properties such as ease of synthesis. [0148] By way of example and not limitation, W³, R^y and R³ are all recursive substituents in certain embodiments. Typically, each of these may independently occur 20, 19, 18, 17, 16, 15, 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1, or 0, times in a given embodiment. More typically, each of these may independently occur 12 or fewer times in a given embodiment. More typically yet, W³ will occur 0 to 8 times, R^y will occur 0 to 6 times and R will occur 0 to 10 times in a given embodiment. Even more typically, W³ will occur 0 to 6 times, R^y will occur 0 to 4 times and R³ will occur 0 to 8 times in a given embodiment. [0149] Recursive substituents are an intended aspect of the embodiments. One of ordinary skill in the art of medicinal chemistry understands the versatility of such substituents. To the degree that recursive substituents are present in an embodiment, the total number will be determined as set forth above.

[0150] In one embodiment Y² is Y^2a, wherein Y^2a is O, N(R^x) or S. In another embodiment Y² is Y^2b, wherein Y^2b is O or N(R^x). In another embodiment Y² is Y²°, wherein Y^2c is O, N(R^y) or S. In another embodiment Y² is Y^2d where Y^2d is

O or N(R^y). In another embodiment Y² is a bond. In another embodiment Y² is

O. In another embodiment Y² is -N(H)-.

[0151] In one embodiment, Y¹ is Y^la wherein Y^1a is O or S. In another embodiment Y¹ is O.

[0152] In one embodiment, R^y is R².

[0153] In one embodiment, R² is H. In another embodiment, R² is R¹.

[0154] In one embodiment, R¹ is H.

[0155] In one embodiment, ml 2a is 1. In another embodiment, ml 2a is ml2d, wherein ml 2d is 1, 2, 3, 4, 5, 6, 7, or 8. In another embodiment, ml 2d is 1.

[0156] In one embodiment, ml 2b is 1. In one embodiment, ml 2b is 0.

[0157] In one embodiment, m2 is 0.

[0158] In one embodiment, W⁶ is W³-A³.

[0159] In one embodiment, W³ is W⁵. In another embodiment, W³ is W^5a. In another embodiment, W³ is W⁴.

[0160] In one embodiment, W⁵ is W^5a, wherein W^5a is a carbocycle independently substituted with 0 or 1 R groups. In one embodiment, W is W , wherein W^5b is a carbocycle or heterocycle optionally substituted with 1, 2, or 3

R² groups.

[0161] The W⁵, W^5a and W^5b carbocycles and W⁵, W^5a and W^5b heterocycles may be a saturated, an unsaturated or an aromatic ring comprising a mono- or bicyclic carbocycle or heterocycle. W⁵, W^5a and W⁵ may have 3 to 10 ring atoms, e.g., 3 to 7 ring atoms. The W⁵, W^5a and W⁵ rings are saturated when containing 3 ring atoms, saturated or mono-unsaturated when containing 4 ring atoms, saturated, or mono- or di-unsaturated when containing 5 ring atoms, and saturated, mono- or di-unsaturated, or aromatic when containing 6 ring atoms.

[0162] A W⁵, W^5a or W^5b heterocycle may be a monocycle having 3 to 7 ring members (2 to 6 carbon atoms and 1 to 3 heteroatoms selected from N, O, P, and

S) or a bicycle having 7 to 10 ring members (4 to 9 carbon atoms and 1 to 3 heteroatoms selected from N, O, P, and S). W⁵, W^5a and W^5b heterocyclic monocycles may have 3 to 6 ring atoms (2 to 5 carbon atoms and 1 to 2 heteroatoms selected from N, O, and S); or 5 or 6 ring atoms (3 to 5 carbon atoms and 1 to 2 heteroatoms selected from N and S). W⁵, W^5a and W^5b heterocyclic bicycles have 7 to 10 ring atoms (6 to 9 carbon atoms and 1 to 2 heteroatoms selected from N, O, and S) arranged as a bicyclo [4,5], [5,5], [5,6], or [6,6] system; or 9 to 10 ring atoms (8 to 9 carbon atoms and 1 to 2 hetero atoms selected from N and S) arranged as a bicyclo [5,6] or [6,6] system. The W⁵, W^5a and W heterocycle may be bonded to Y through a carbon, nitrogen, sulfur or other atom by a stable covalent bond.

[0163] The W⁵, W^5a and W^5b heterocycles include for example, pyridyl, dihydropyridyl isomers, piperidine, pyridazinyl, pyrimidinyl, pyrazinyl, s- triazinyl, oxazolyl, imidazolyl, thiazolyl, isoxazolyl, pyrazolyl, isothiazolyl, furanyl, thiofuranyl, thienyl, and pyrrolyl. W⁵, W^5a and W^5b also include, but are not limited to, examples such as:

[0164] Substituted W⁵ carbocycles include, for example:

[0165] In one embodiment, each A⁰ is independently selected from A¹, A² or W³ with the proviso that the compound of Formula I includes at least one A . In another embodiment, A⁰ is A¹. [0166] In one embodiment, A¹ is of the formula:

wherein W⁶ is W³-A³. In another embodiment of A¹ having the formula above, W⁶ is W³-A³ and at least one Y² is a bond. In another embodiment, W⁶ is W³-A³, each Y² is a bond and ml 2a is 1. In another embodiment of A¹ having the formula above, W⁶ is W^5a-A³, each Y² is a bond and ml 2b is 1. In another embodiment of A¹ having the formula above W is W ₇5a-A , each Y is a bond and ml 2a and ml 2b are 1. [0167] In one embodiment, A² is of the formula:

wherein W³ is W⁵. In another embodiment of A² having the formula above, W³ is W⁵ and at least one Y² is a bond. In another embodiment of A² having the formula above,

W³ is W⁵ and at least one Y² is a bond and ml 2b is 1. In another embodiment of A² having the formula above, W³ is W⁵ and each Y² is a bond. In another embodiment of A² having the formula above, W³ is W^5b, each Y² is a bond and ml 2b is 0. In another embodiment of A² having the formula above, W³ is W^5b, each Y² is a bond, ml 2b is 1, and ml 2a is 1. In another embodiment of A² having the formula above, W³ is W⁴. In another embodiment of A² having the formula above, W³ is W⁴ and at least one Y² is a bond. In another embodiment of A² having the formula above W³ is W⁴ and at least one

Y² is a bond and ml 2b is 1.

[0168] In another embodiment, A² is selected from phenyl, substituted phenyl, benzyl, substituted benzyl, pyridinyl, and substituted pyridinyl.

[0169] Embodiments of A³ include phenyl phosphonamidate amino acid, e.g. alanate esters and phenyl phosphonate-lactate esters. The chiral carbon of the amino acid and lactate moieties may be either the R or S configuration or the racemic mixture.

[0170] In one embodiment, A³ is of the formula:

where m2 is 0. In another embodiment of A having the formula above m2 is 0 and ml 2b is 1. In another embodiment of A³ having the formula above m2 and ml 2b are 0 and Y¹ is Y^la, and Y² is Y^2a, where Y^la and Y^2a are defined above. [0171] In one embodiment, A³ is of the formula:

In another embodiment of A³ having the formula above Y^2b is O and ml 2a is 1. In another embodiment of A³ having the formula above ml 2a is ml2d, wherein ml2d is defined as above. In another embodiment of A³ having the formula above ml 2a is ml2d and R² is H. In another embodiment of A³ having the formula above ml 2a is 1, and R² is H.

[0172] In one embodiment, A³ is of the formula:

In another embodiment, A³ is of the formula above wherein W³ is W⁵. In another embodiment, A³ is of the formula above wherein ml 2b is 1. In another embodiment, A is of the formula above wherein ml 2b is 1 Y¹ is Y^la and Y² is Y^2a as defined above. In another embodiment, A³ is of the formula above wherein ml 2b is 1 Y¹ is O and Y² is

[0173] In another embodiment, A³ is of the formula:

[0174] In another embodiment, A³ is of the formula above, wherein R² is R¹ and ml 2a is ml2d. In another embodiment of A³ having the formula above, R² is H and ml 2a is ml2d. In another embodiment, A³ is of the formula above, wherein R² is R¹ and ml 2a is ml2d.

[0175] In another embodiment, A³ is of the formula:

In another embodiment of A³ having the formula above, ml2d is 1, 2, 3, 4, 5, 6, 7 or 8 and R¹ is H. In another embodiment of A having the formula above, ml2d is 1. [0176] In another embodiment, A³ is of the formula:

[0177] In another embodiment, A³ is of the formula:

In another embodiment of A³ having the formula above there are zero R² substituents on the phenoxy group. [0178] In one embodiment, A³ is of the formula:

In another embodiment of A³ having the formula above, W⁵ is phenyl. [0179] Not withstanding other disclosure herein which describes the role or presence of phosphonates in the compounds of the embodiments, in another embodiment, A³ is A^3a which is of the formula:

In this embodiment, any A³ group may be A^3a.

[0180] In another aspect of the embodiments, A³ is of the formula:

ml 2a is other than 0 and at least one phosphonate group present in the compound is not bonded directly to W³. More typically, the phosphonate is not bonded directly to W⁵. In such an embodiment, the phosphorous atom of the phosphonate is not bonded directly to a carbon atom of a ring. [0181] Embodiments of R^x include esters, carbamates, carbonates, thioesters, amides, thioamides, and urea groups. In one embodiment R^x is of the formula:

In another embodiment of R^x having the formula above, one R² is H, ml 2a is 1, Y¹ is Y^la, and Y² is Y²°, wherein Y^la and Y^2c are as defined above. In another embodiment of R^x having the formula above, one R² is H, ml 2a is 1, Y¹ is Y^la, and Y² is Y^2d, wherein Y^2d is as defined above. In another embodiment of R^x having the formula above, one R² is H, ml 2a is 1, Y¹ is O, and Y² is O. In another embodiment of R^x having the formula above, one R² is H, ml 2a is 1, Y¹ is O, Y² is O, and R^y is R². [0182] In another embodiment, R^x is of the formula:

[0183] In one embodiment, A is of the formula:

and R^x is of the formula:

[0184] In one embodiment, A is of the formula:

and R^x is of the formula:

[0185] In one embodiment, A is of the formula:

and R^x is of the formula:

[0186] In one embodiment, A³ is of the formula:

and R^x is of the formula:

In another embodiment, wherein A³ and R^x are of the formulae shown above, in A³ ml 2a is ml2d and Y²° is Y^2d.

[0187] In one embodiment, A³ is of the formula:

and R^x is of the formula:

In another embodiment, wherein A³ and R^x are of the formulae shown above, in A³ ml2d is 1, and R^y is R². In another embodiment, where A³ and R^x are of the formulae shown above, A³ is of the formula:

[0188] In one embodiment, A is of the formula:

and R^x is of the formula:

In another embodiment, wherein A³ and R^x are of the formulae shown above, A is of the formula:

In another embodiment, wherein A³ and R^x are of the formulae shown above, A³ is of the formula:

In another embodiment, wherein A³ and R^x are of the formulae shown above, A³ is of the formula:

In another embodiment, wherein A and R^x are of the formulae shown above, A³ is of the formula:

In another embodiment, wherein A³ and R^x are of the formulae shown above, A³ is of the formula:

[0189] In one embodiment, A¹ is of the formula:

and A is of the formula:

[0190] In another embodiment, A¹ is of the formula:

A³ is of the formula:

and R^x is of the formula:

In another embodiment, wherein A¹, A³ and R^x are of the formulae shown above, A¹ is of the formula:

and A is of the formula:

In

above, A¹ is of the formula:

and A is of the formula:

In another embodiment, wherein A , A and R^x are of the formulae shown above, A is of the formula:

and A is of the formula:

[0191] In one embodiment, at least one A⁰ is of the formula:

[0192] In one embodiment, at least one A⁰ is of the formula:

[0193] In one embodiment, A¹ is of the formula:

and A _L 3 is of the formula:

[0194] In another embodiment, A is of the formula:

and A³ is of the formula:

and R^x is of the formula:

In another embodiment, wherein A¹, A³ and R^x are of the formulae shown above, A is of the formula:

and A³ is of the formula:

In another embodiment, wherein A¹, A³ and R^x are of the formulae shown above, A is of the formula:

and A ι 3 i .s of the formula:

In another embodiment, wherein A , A and R are of the formulae shown above, A is of the formula:

In another embodiment, wherein A , A and R^x are of the formulae shown above, A is of the formula:

and A is of the formula:

In another embodiment of A shown above, Y is O and W is phenyl. In another embodiment, wherein A , A and R^x are of the formulae shown above, A is of the formula:

In another embodiment, wherein A , A and R^x are of the formulae shown above, A is of the formula:

[0195] In one embodiment, at least one A⁰ is of the formula:

Exemplary Enumerated Compounds.

[0196] By way of example and not limitation, embodiments are named below in tabular format (Table 100). These embodiments are of the general formula

"MBF":

MBF [0197] Each embodiment of MBF is depicted as a substituted nucleus (Sc) in which the nucleus is designated by a number and each substituent is designated in order by letter or number. Tables 1.1 to 1.8 are a schedule of nuclei used in forming the embodiments of Table 100. Each nucleus (Sc) is given a number designation from Tables 1.1 to 1.8, and this designation appears first in each embodiment name. Similarly, Tables 10.1 to 10.19 and 20.1 to 20.36 list the selected linking groups (Lg) and prodrug (Pd¹ and Pd²) substituents, again by letter or number designation, respectively.

[0198] Accordingly, each named embodiment of Table 100 is depicted by a number designating the nucleus from Table 1.1-1.5, followed by a letter designating the linking group (Lg) from Table 10.1-10.19, and two numbers designating the two prodrug groups (Pd¹ and Pd²) from Table 20.1-20.36. In graphical tabular form, each embodiment of Table 100 appears as a name having the syntax:

Thus, ignoring stereochemistry, structure 10, Scheme 2, Scheme Section A, is represented by 2.AB.247.247.

[0199] Each Sc group is shown having a tilda ("-")• The tilda is the point of covalent attachment of Sc to Lg. Q¹ and Q² of the linking groups (Lg), it should be understood, do not represent groups or atoms but are simply connectivity designations. Q¹ is the site of the covalent bond to the nucleus (Sc) and Q² is the site of the covalent bond to the phosphorous atom of formula MBF. Each prodrug group (Pd¹ and Pd²) are covalently bonded to the phosphorous atom of MBF at the tilda symbol ("~"). Some embodiments of Tables 10.1-10.19 and 20.1-20.36 may be designated as a combination of letters and numbers (Table 10.1-10.19) or number and letter (Table 20.1-20.36). For example there are Table 10 entries for BJl and BJ2. In any event, entries of Table 10.1-10.19 always begin with a letter and those of Table 20.1-20.36 always begin with a number. When a nucleus (Sc) is shown enclosed within square brackets ("[]") and a covalent bond extends outside the brackets, the point of covalent attachment of Sc to Lg may be at any substitutable site on SC. Selection of the point of attachment is described herein. By way of example and not limitation, the point of attachment is selected from those depicted in the schemes and examples.

Table 1.1

Table 1.3

Table 1.4

12

Table 1.5

Table 1.7

Table 1.8

Table 10.1

Table 10.2

Table 10.4 No table 10.4

Table 10.5

Table 10.6

Table 10.7

Table 10.8

Table 10.9

Table 10.10

Table 10.11

Table 10.12

Table 10.13

Table 10.14

Table 10.15

Table 10.16

Table 10.17

86 Table 10.18

Table 10.19

Table 20.1

Table 20.2

Table 20.3

Table 20.4

Table 20.5

Table 20.6

Table 20.7

Table 20.8

Table 20.9

Table 20.10

Table 20.11

Table 20.12

Table 20.13

Table 20.14

Table 20.15

Table 20.16

Table 20.17

Table 20.18

Table 20.19

Table 20.20

Table 20.21

Table 20.22

Table 20.23

Table 20.24

Table 20.25

Table 20.26

Table 20.27

Table 20.28

Table 20.29

193 Table 20.30

Table 20,31

Table 20.32

Table 20.33

Table 20.34

226

Table 20.35

Table 20.36

Table 20.37

Table 100

Prodrugs of l.B l.B.228.228; l.B.228.229; l.B.228.230; l.B.228.231; l.B.228.236; l.B.228.237; l.B.228.238; l.B.228.239; l.B.228.154; l.B.228.157; l.B.228.166; l.B.228.169; l.B.228.172; l.B.228.175; l.B.228.240; l.B.228.244; l.B.229.228; l.B.229.229; l.B.229.230; l.B.229.231; l.B.229.236; l.B.229.237; l.B.229.238; l.B.229.239; l.B.229.154; l.B.229.157; l.B.229.166; l.B.229.169; l.B.229.172; l.B.229.175; l.B.229.240; l.B.229.244; l.B.230.228; l.B.230.229; l.B.230.230; l.B.230.231; l.B.230.236; l.B.230.237; l.B.230.238; l.B.230.239; l.B.230.154; l.B.230.157; l.B.230.166; l.B.230.169; l.B.230.172; l.B.230.175; l.B.230.240; l.B.230.244; l.B.231.228; l.B.231.229; l.B.231.230; l.B.231.231; l.B.231.236; l.B.231.237; l.B.231.238; l.B.231.239; l.B.231.154; l.B.231.157; l.B.231.166; l.B.231.169; l.B.231.172; l.B.231.175; l.B.231.240; l.B.231.244; l.B.236.228; l.B.236.229; l.B.236.230; l.B.236.231; l.B.236.236; l.B.236.237; l.B.236.238; l.B.236.239; l.B.236.154; l.B.236.157; l.B.236.166; l.B.236.169; l.B.236.172; l.B. ,236-175; l.B.236.240; l.B.236.244; l.B.237.228; l.B.237.229; l.B.237.230; IB.237.231; l.B.237.236; l.B.237.237; l.B.237.238; l.B.237.239; l.B.237.154; l.B.237.157; l.B.237.166; l.B.237.169; l.B.237.172; l.B.237.175; l.B.237.240; l.B.237.244; l.B.238.228; l.B.238.229; l.B.238.230; l.B.238.231; l.B.238.236; l.B.238.237; l.B.238.238; l.B.238.239; l.B.238.154; l.B.238.157; l.B.238.166; l.B.238.169; l.B.238.172; l.B.238.175; l.B.238.240; l.B.238.244; l.B.239.228; l.B.239.229; l.B.239.230; l.B.239.231; l.B.239.236; l.B.239.237; l.B.239.238; l.B.239.239; l.B.239.154; l.B.239.157; l.B.239.166; l.B.239.169; l.B.239.172; l.B.239.175; l.B.239.240; l.B.239.244; l.B.154.228; l.B.154.229; l.B.154.230; l.B.154.231; l.B.154.236; l.B.154.237; l.B.154.238; l.B.154.239; l.B.154.154; l.B.154.157; l.B.154.166; l.B.154.169; l.B.154.172; l.B.154.175; l.B.154.240; l.B.154.244; l.B.157.228; l.B.157.229; l.B.157.230; l.B.157.231; l.B.157.236; l.B.157.237; l.B.157.238; l.B..157..239; l.B.157.154; l.B.157.157; l.B.157.166; l.B.157.169; l.B.157.172; l.B.157.175; l.B.157.240; l.B.157.244; l.B.166.228; l.B.166.229; l.B.166.230; l.B.166.231; l.B.166.236; l.B.166.237; l.B.166.238; l.B.166.239; l.B.166.154; l.B.166.157; l.B.166.166; l.B.166.169; l.B.166.172; l.B.166.175; l.B.166.240; l.B.166.244; l.B.169.228; l.B.169.229; l.B.169.230; l.B.169.231; l.B.169.236; l.B.169.237; l.B.169.238; l.B.169.239; l.B.169.154; l.B.169.157; l.B.169.166; l.B.169.169; l.B.169.172; l.B.169.175; l.B.169.240; l.B.169.244; l.B.172.228; l.B.172.229; l.B.172.230; l.B.172.231; l.B.172.236; l.B.172.237; l.B.172.238; l.B.172.239; l.B.172.154; l.B.172.157; l.B.172.166; l.B.172.169; l.B.172.172; l.B.172.175; l.B.172.240; l.B.172.244; l.B.175.228; l.B.175.229; l.B.175.230; l.B.175.231; l.B.175.236; l.B.175.237; l.B.175.238; l.B.175.239; l.B.175.154; l.B.175.157; l.B.175.166; l.B.175.169; l.B.175.172; l.B.175.175; l.B.175.240; l.B.175.244; l.B.240.228; l.B.240.229; l.B.240.230; l.B.240.231; l.B.240.236; l.B.240.237; l.B.240.238; l.B.240.239; l.B.240.154; l.B.240.157; l.B.240.166; l.B.240.169; l.B.240.172; l.B.240.175; l.B.240.240; l.B.240.244; l.B.244.228; l.B.244.229; l.B.244.230; l.B.244.231; l.B.244.236; l.B.244.237; l.B.244.238; l.B.244.239; l.B.244.154; l.B.244.157; l.B.244.166; l.B.244.169; l.B.244.172; l.B.244.175; l.B.244.240; l.B.244.244; Prodrugs of l.D l.D.228.228; l.D.228.229; l.D.228.230; l.D.228.231; l.D.228.236; 1JD.228.237; l.D.228.238; l.D.228.239; l.D.228.154; l.D.228.157; l.D.228.166; l.D.228.169; l.P.228.172; l.D.228.175; l.D.228.240; l.D.228.244; l.D.229.228; l.D.229.229; l.D.229.230; l.D.229.231; l.D.229.236; l.D.229.237; l.D.229.238; l.D.229.239; l.D.229.154; l.D.229.157; l.D.229.166; l.D.229.169; l.D.229.172; l.D.229.175; l.D.229.240; l.D.229.244; l.D.230.228; l.D.230.229; l.D.230.230; l.D.230.231; l.D.230.236; l.D.230.237; l.D.230.238; l.D.230.239; l.D.230.154; l.D.230.157; l.D.230.166; l.D.230.169; l.D.230.172; l.D.230.175; l.D.230.240; l.D.230.244; l.D.231.228; l.D.231.229; l.D.231.230; l.D.231.231; l.D.231.236; l.D.231.237; l.D.231.238; l.D.231.239; l.D.231.154; l.D.231.157; l.D.231.166; l.D.231.169; l.D.231.172; l.D.231.175; l.D.231.240; l.D.231.244; l.D.236.228; l.D.236.229; l.D.236.230; l.D.236.231; l.D.236.236; l.D.236.237; l.D.236.238; l.D.236.239; l.D.236.154; l.D.236.157; l.D.236.166; l.D.236.169; l.D.236.172; l.D.236.175; l.D.236.240; l.D.236.244; l.D.237.228; l.D.237.229; l.D.237.230; l.D.237.231; l.D.237.236; l.D.237.237; l.D.237.238; l.D.237.239; l.D.237.154; l.D.237.157; l.D.237.166; l.D.237.169; l.D.237.172; l.D.237.175; l.D.237.240; l.D.237.244; l.D.238.228; l.D.238.229; l.D.238.230; l.D.238.231; l.D.238.236; l.D.238.237; l.D.238.238; l.D.238.239; l.D.238.154; l.D.238.157; l.D.238.166; l.D.238.169; l.D.238.172; l.D.238.175; l.D.238.240; l.D.238.244; l.D.239.228; l.D.239.229; l.D.239.230; l.D.239.231; l.D.239.236; l.D.239.237; l.D.239.238; l.D.239.239; l.D.239.154; l.D.239.157; l.D.239.166; l.D.239.169; l.D.239.172; l.D.239.175; l.D.239.240; l.D.239.244; l.D.154.228; l.D.154.229; l.D.154.230; l.D.154.231; l.D.154.236; l.D.154.237; l.D.154.238; l.D.154.239; l.D.154.154; l.D.154.157; l.D.154.166; l.D.154.169; l.D.154.172; l.D.154.175; l.D.154.240; l.D.154.244; l.D.157.228; l.D.157.229; l.D.157.230; l.D.157.231; l.D.157.236; l.D.157.237; l.D.157.238; l.D.157.239; l.D.157.154; l.D.157.157; l.D.157.166; l.D.157.169; l.D.157.172; l.D.157.175; l.D.157.240; l.D.157.244; l.D.166.228; l.D.166.229; l.D.166.230; l.D.166.231; l.D.166.236; l.D.166.237; l.D.166.238; l.D.166.239; l.D.166.154; l.D.166.157; l.D.166.166; l.D.166.169; l.D.166.172; l.D.166.175; l.D.166.240; l.D.166.244; l.D.169.228; l.D.169.229; l.D.169.230; l.D.169.231; l.D.169.236; l.D.169.237; l.D.169.238; l.D.169.239; l.D.169.154; l.D.169.157; l.D.169.166; l.D.169.169; l.D.169.172; l.D.169.175; l.D.169.240; l.D.169.244; l.D.172.228; l.D.172.229; l.D.172.230; l.D.172.231; l.D.172.236; l.D.172.237; l.D.172.238; l.D.172.239; l.D.172.154; l.D.172.157; l.D.172.166; l.D.172.169; l.D.172.172; l.D.172.175; l.D.172.240; l.D.172.244; l.D.175.228; l.D.175.229; l.D.175.230; l.D.175.231; l.D.175.236; l.D.175.237; l.D.175.238; l.D.175.239; l.D.175.154; l.D.175.157; l.D.175.166; l.D.175.169; l.D.175.172; l.D.175.175; l.D.175.240; l.D.175.244; l.D.240.228; l.D.240.229; l.D.240.230; l.D.240.231; l.D.240.236; l.D.240.237; l.D.240.238; l.D.240.239; l.D.240.154; l.D.240.157; l.D.240.166; l.D.240.169; l.D.240.172; l.D.240.175; l.D.240.240; 1.D.24Q.244; l.D.244.228; l.D.244.229; l.D.244.230; l.D.244.231; l.D.244.236; l.D.244.237; l.D.244.238; l.D.244.239; l.D.244.154; l.D.244.157; l.D.244.166; l.D.244.169; l.D.244.172; l.D.244.175; l.D.244.240; l.D.244.244; Prodrugs of l.AB l.AB.228.228; l.AB.228.229; l.AB.228.230; l.AB.228.231; l.AB.228.236; l.AB.228.237; l.AB.228.238; l.AB.228.239; l.AB.228.154; l.AB.228.157; l.AB.228.166; l.AB.228.169; l.AB.228.172; l.AB.228.175; l.AB.228.240; l.AB.228.244; l.AB.229.228; l.AB.229.229; l.AB.229.230; l.AB.229.231; l.AB.229.236; l.AB.229.237; l.AB.229.238; l.AB.229.239; l.AB.229.154; l.AB.229.157; l.AB.229.166; l.AB.229.169; l.AB.229.172; l.AB.229.175; l.AB.229.240; l.AB.229.244; l.AB.230.228; l.AB.230.229; l.AB.230.230; l.AB.230.231; l.AB.230.236; l.AB.230.237; l.AB.230.238; 1.AB.23Q.239; l.AB.230.154; l.AB.230.157; l.AB.230.166; l.AB.230.169; l.AB.230.172; l.AB.230.175; l.AB.230.240; l.AB.230.244; l.AB.231.228; l.AB.231.229; l.AB.231.230; l.AB.231.231; l.AB.231.236; l.AB.231.237; l.AB.231.238; l.AB.231.239; l.AB.231.154; l.AB.231.157; l.AB.231.166; l.AB.231.169; l.AB.231.172; l.AB.231.175; l.AB.231.240; l.AB.231.244; l.AB.236.228; l.AB.236.229; l.AB.236.230; l.AB.236.231; l.AB.236.236; l.AB.236.237; l.AB.236.238; l.AB.236.239; l.AB.236.154; l.AB.236.157; l.AB.236.166; l.AB.236.169; l.AB.236.172; l.AB.236.175; l.AB.236.240; l.AB.236.244; l.AB.237.228; l.AB.237.229; l.AB.237.230; l.AB.237.231; l.AB.237.236; l.AB.237.237; l.AB.237.238; l.AB.237.239; l.AB.237.154; l.AB.237.157; l.AB.237.166; l.AB.237.169; l.AB.237.172; l.AB.237.175; l.AB.237.240; l.AB.237.244; l.AB.238.228; l.AB.238.229; l.AB.238.230; l.AB.238.231; l.AB.238.236; l.AB.238.237; l.AB.238.238; l.AB.238.239; l.AB.238.154; l.AB.238.157; l.AB.238.166; l.AB.238.169; l.AB.238.172; l.AB.238.175; l.AB.238.240; l.AB.238.244; l.AB.239.228; l.AB.239.229; l.AB.239.230; l.AB.239.231; l.AB.239.236; l.AB.239.237; l.AB.239.238; l.AB.239.239; l.AB.239.154; l.AB.239.157; l.AB.239.166; l.AB.239.169; l.AB.239.172; l.AB.239.175; l.AB.239.240; l.AB.239.244; l.AB.154.228; l.AB.154.229; l.AB.154.230; l.AB.154.231; l.AB.154.236; l.AB.154.237; l.AB.154.238; l.AB.154.239; l.AB.154.154; l.AB.154.157; l.AB.154.166; l.AB.154.169; l.AB.154.172; l.AB.154.175; l.AB.154.240; l.AB.154.244; l.AB.157.228; l.AB.157.229; l.AB.157.230; l.AB.157.231; l.AB.157.236; l.AB.157.237; l.AB.157.238; l.AB.157.239; l.AB.157.154; l.AB.157.157; l.AB.157.166; l.AB.157.169; l.AB.157.172; l.AB.157.175; l.AB.157.240; l.AB.157.244; l.AB.166.228; l.AB.166.229; l.AB.166.230; l.AB.166.231; l.AB.166.236; l.AB.166.237; l.AB.166.238; l.AB.166.239; l.AB.166.154; l.AB.166.157; l.AB.166.166; l.AB.166.169; l.AB.166.172; l.AB.166.175; l.AB.166.240; l.AB.166.244; l.AB.169.228; l.AB.169.229; l.AB.169.230; l.AB.169.231; l.AB.169.236; l.AB.169.237; l.AB.169.238; l.AB.169.239; l.AB.169.154; l.AB.169.157; l.AB.169.166; l.AB.169.169; l.AB.169.172; l.AB.169.175; l.AB.169.240; l.AB.169.244; l.AB.172.228; l.AB.172.229; l.AB.172.230; l.AB.172.231; l.AB.172.236; l.AB.172.237; l.AB.172.238; l.AB.172.239; l.AB.172.154; l.AB.172.157; l.AB.172.166; l.AB.172.169; l.AB.172.172; l.AB.172.175; l.AB.172.240; l.AB.172.244; l.AB.175.228; l.AB.175.229; l.AB.175.230; l.AB.175.231; l.AB.175.236; l.AB.175.237; l.AB.175.238; l.AB.175.239; l.AB.175.154; l.AB.175.157; l.AB.175.166; l.AB.175.169; l.AB.175.172; l.AB.175.175; l.AB.175.240; l.AB.175.244; l.AB.240.228; l.AB.240.229; l.AB.240.230; l.AB.240.231; l.AB.240.236; 1.AB.24Q.237; l.AB.240.238; l.AB.240.239; l.AB.240.154; l.AB.240.157; l.AB.240.166; l.AB.240.169; 1. AB.240.172; l.AB.240.175; l.AB.240.240; l.AB.240.244; l.AB.244.228; l.AB.244.229; l.AB.244.230; l.AB.244.231; l.AB.244.236; l.AB.244.237; l.AB.244.238; l.AB.244.239; l.AB.244.154; l.AB.244.157; l.AB.244.166; l.AB.244.169; l.AB.244.172; l.AB.244.175; l.AB.244.240; l.AB.244.244;

Prodrugs of l.BI l.BI.228.228; l.BI.228.229; l.BI.228.230; l.BI.228.231; l.BI.228.236; l.BI.228.237; l.BI.228.238; l.BI.228.239; l.BI.228.154; l.BI.228.157; l.BI.228.166; l.BI.228.169; l.BI.228.172; l.BI.228.175; l.BI.228.240; l.BI.228.244; l.BI.229.228; l.BI.229.229; l.BI.229.230; l.BI.229.231; l.BI.229.236; l.BI.229.237; l.BI.229.238; l.BI.229.239; l.BI.229.154; l.BI.229.157; l.BI.229.166; l.BI.229.169; l.BI.229.172; l.BI.229.175; l.BI.229.240; l.BI.229.244; l.BI.230.228; l.BI.230.229; l.BI.230.230; l.BI.230.231; l.BI.230.236; l.BI.230.237; l.BI.230.238; l.BI.230.239; l.BI.230.154; l.BI.230.157; l.BI.230.166; l.BI.230.169; l.BI.230.172; l.BI.230.175; l.BI.230.240; l.BI.230.244; l.BI.231.228; l.BI.231.229; l.BI.231.230; l.BI.231.231; l.BI.231.236; l.BI.231.237; l.BI.231.238; l.BI.231.239; l.BI.231.154; l.BI.231.157; l.BI.231.166; l.BI.231.169; l.BI.231.172; l.BI.231.175; l.BI.231.240; l.BI.231.244; l.BI.236.228; l.BI.236.229; l.BI.236.230; l.BI.236.231; l.BI.236.236; l.BI.236.237; l.BI.236.238; l.BI.236.239; l.BI.236.154; l.BI.236.157; l.BI.236.166; l.BI.236.169; l.BI.236.172; l.BI.236.175; l.BI.236.240; l.BI.236.244; l.BI.237.228; l.BI.237.229; l.BI.237.230; l.BI.237.231; l.BI.237.236; l.BI.237.237; l.BI.237.238; l.BI.237.239; l.BI.237.154; l.BI.237.157; l.BI.237.166; l.BI.237.169; l.BI.237.172; l.BI.237.175; l.BI.237.240; l.BI.237.244; l.BI.238.228; l.BI.238.229; l.BI.238.230; l.BI.238.231; l.BI.238.236; l.BI.238.237; l.BI.238.238; l.BI.238.239; l.BI.238.154; l.BI.238.157; l.BI.238.166; l.BI.238.169; l.BI.238.172; l.BI.238.175; l.BI.238.240; l.BI.238.244; l.BI.239.228; l.BI.239.229; l.BI.239.230; l.BI.239.231; l.BI.239.236; l.BI.239.237; l.BI.239.238; l.BI.239.239; l.BI.239.154; 1.BL239.157; l.BI.239.166; l.BI.239.169; l.BI.239.172; l.BI.239.175; l.BI.239.240; l.BI.239.244; l.BI.154.228; l.BI.154.229; l.BI.154.230; l.BI.154.231; l.BI.154.236; l.BI.154.237; l.BI.154.238; l.BI.154.239; l.BI.154.154; l.BI.154.157; l.BI.154.166; l.BI.154.169; l.BI.154.172; l.BI.154.175; l.BI.154.240; l.BI.154.244; l.BI.157.228; l.BI.157.229; l.BI.157.230; l.BI.157.231; l.BI.157.236; l.BI.157.237; l.BI.157.238; l.BI.157.239; l.BI.157.154; l.BI.157.157; l.BI.157.166; l.BI.157.169; l.BI.157.172; l.BI.157.175; l.BI.157.240; l.BI.157.244; l.BI.166.228; l.BI.166.229; l.BI.166.230; l.BI.166.231; l.BI.166.236; l.BI.166.237; l.BI.166.238; l.BI.166.239; l.BI.166.154; l.BI.166.157; l.BI.166.166; l.BI.166.169; l.BI.166.172; l.BI.166.175; l.BI.166.240; l.BI.166.244; 1.BL169.228; l.BI.169.229; l.BI.169.230; l.BI.169.231; l.BI.169.236; l.BI.169.237; l.BI.169.238; l.BI.169.239; l.BI.169.154; l.BI.169.157; l.BI.169.166; l.BI.169.169; l.BI.169.172; l.BI.169.175; l.BI.169.240; l.BI.169.244; l.BI.172.228; l.BI.172.229; l.BI.172.230; l.BI.172.231; l.BI.172.236; l.BI.172.237; l.BI.172.238; l.BI.172.239; l.BI.172.154; 131.172.157; l.BI.172.166; l.BI.172.169; l.BI.172.172; l.BI.172.175; l.BI.172.240; l.BI.172.244; l.BI.175.228; l.BI.175.229; l.BI.175.230; l.BI.175.231; l.BI.175.236; l.BI.175.237; l.BI.175.238; l.BI.175.239; l.BI.175.154; l.BI.175.157; l.BI.175.166; l.BI.175.169; l.BI.175.172; l.BI.175.175; l.BI.175.240; l.BI.175.244; l.BI.240.228; l.BI.240.229; l.BI.240.230; l.BI.240.231; l.BI.240.236; l.BI.240.237; l.BI.240.238; l.BI.240.239; l.BI.240.154; l.BI.240.157; l.BI.240.166; l.BI.240.169; l.BI.240.172; l.BI.240.175; l.BI.240.240; l.BI.240.244; l.BI.244.228; l.BI.244.229; l.BI.244.230; l.BI.244.231; l.BI.244.236; l.BI.244.237; l.BI.244.238; l.BI.244.239; l.BI.244.154; l.BI.244.157; l.BI.244.166; l.BI.244.169; l.BI.244.172; l.BI.244.175; l.BI.244.240; l.BI.244.244;

Prodrugs of 1.1

1.1.228.228; 1.1.228.229; 1.1.228.230; 1.1.228.231; 1.1.228.236; 1.1.228.237; 1.1.228.238; 1.1.228.239; 1.1.228.154; 1.1.228.157; 1.1.228.166; 1.1.228.169; 1.1.228.172; 1.1.228.175; 1.1.228.240; 1.1.228.244; 1.1.229.228; 1.1.229.229; 1.1.229.230; 1.1.229.231; 1.1.229.236; 1.1.229.237; 1.1.229.238; 1.1.229.239; 1.1.229.154; 1.1.229.157; 1.1.229.166; 1.1.229.169; 1.1.229.172; 1.1.229.175; 1.1.229.240; 1.1.229.244; 1.1.230.228; 1.1.230.229; 1.1.230.230; 1.1.230.231; 1.1.230.236; 1.1.230.237; 1.1.230.238; 1.1.230.239; 1.1.230.154; 1.1.230.157; 1.1.230.166; 1.1.230.169; 1.1.230.172; 1.1.230.175; 1.1.230.240; 1.1.230.244; 1.1.231.228; 1.1.231.229; 1.1.231.230; 1.1.231.231; 1.1.231.236; 1.1.231.237; 1.1.231.238; 1.1.231.239; 1.1.231.154; 1.1.231.157; 1.1.231.166; 1.1.231.169; 1.1.231.172; 1.1.231.175; 1.1.231.240; 1.1.231.244; 1.1.236.228; 1.1.236.229; 1.1.236.230; 1.1.236.231; 1.1.236.236; 1.1.236.237; 1.1.236.238; 1.1.236.239; 1.1.236.154; 1.1.236.157; 1.1.236.166; 1.1.236.169; 1.1.236.172; 1.1.236.175; 1.1.236.240; 1.1.236.244; 1.1.237.228; 1.1.237.229; 1.1.237.230; 1.1.237.231; 1.1.237.236; 1.1.237.237; 1.1.237.238; 1.1.237.239; 1.1.237.154; 1.1.237.157; 1.1.237.166; 1.1.237.169; 1.1.237.172; 1.1.237.175; 1.1.237.240; 1.1.237.244; 1.1.238.228; 1.1.238.229; 1.1.238.230; 1.1.238.231; 1.1.238.236; 1.1.238.237; 1.1.238.238; 1.1.238.239; 1.1.238.154; 1.1.238.157; 1.1.238.166; 1.1.238.169; 1.1.238.172; 1.1.238.175; 1.1.238.240; 1.1.238.244; 1.1.239.228; 1.1.239.229; 1.1.239.230; 1.1.239.231; 1.1.239.236; 1.1.239.237; 1.1.239.238; 1.1.239.239; 1.1.239.154; 1.1.239.157; 1.1.239.166; 1.1.239.169; 1.1.239.172; 1.1.239.175; 1.1.239.240; 1.1.239.244; 1.1.154.228; 1.1.154.229; 1.1.154.230; 1.1.154.231; 1.1.154.236; 1.1.154.237; 1.1.154.238; 1.1.154.239; 1.1.154.154; 1.1.154.157; 1.1.154.166; 1.1.154.169; 1.1.154.172; 1.1.154.175; 1.1.154.240; 1.1.154.244; 1.1.157.228; 1.1.157.229; 1.1.157.230; 1.1.157.231; 1.1.157.236; 1.1.157.237; 1.1.157.238; 1.1.157.239; 1.1.157.154; 1.1.157.157; 1.1.157.166; 1.1.157.169; 1.1.157.172; 1.1.157.175; 1.1.157.240; 1.1.157.244; 1.1.166.228; 1.1.166.229; 1.1.166.230; 1.1.166.231; 1.1.166.236; 1.1.166.237; 1.1.166.238; 1.1.166.239; 1.1.166.154; 1.1.166.157; 1.1.166.166; 1.1.166.169; 1.1.166.172; 1.1.166.175; 1.1.166.240; 1.1.166.244; 1.1.169.228; 1.1.169.229; 1.1.169.230; 1.1.169.231; 1.1.169.236; 1.1.169.237; 1.1.169.238; 1.1.169.239; 1.1.169.154; 1.1.169.157; 1.1.169.166; 1.1.169.169; 1.1.169.172; 1.1.169.175; 1.1.169.240; 1.1.169.244; 1.1.172.228; 1.1.172.229; 1.1.172.230; 1.1.172.231; 1.1.172.236; 1.1.172.237; 1.1.172.238; 1.1.172.239; 1.1.172.154; 1.1.172.157; 1.1.172.166; 1.1.172.169; 1.1.172.172; 1.1.172.175; 1.1.172.240; 1.1.172.244; 1.1.175.228; 1.1.175.229; 1.1.175.230; 1.1.175.231; 1.1.175.236; 1.1.175.237; 1.1.175.238; 1.1.175.239; 1.1.175.154; 1.1.175.157; 1.1.175.166; 1.1.175.169; 1.1.175.172; 1.1.175.175; 1.1.175.240; 1.1.175.244; 1.1.240.228; 1.1.240.229; 1.1.240.230; 1.1.240.231; 1.1.240.236; 1.1.240.237; 1.1.240.238; 1.1.240.239; 1.1.240-154; 1.1.240.157; 1.1.240.166; 1.1.240.169; 1.1.240.172; 1.1.240.175; 1.1.240.240; 1.1.240.244; 1.1.244.228; 1.1.244.229; 1.1.244.230; 1.1.244.231; 1.1.244.236; 1.1.244.237; 1.1.244.238; 1.1.244.239; 1.1.244.154; 1.1.244.157; 1.1.244.166; 1.1.244.169; 1.1.244.172; 1.1.244.175; 1.1.244.240; 1.1.244.244; Prodrugs of IJ l.J.228.228; 1J.228.229; l.J.228.230; 1J.228.231; l.J.228.236; l.J.228.237; l.J.228.238; l.J.228.239; 1J.228.154; l.J.228.157; l.J.228.166; l.J.228.169; 1J.228.172; l.J.228.175; l.J.228.240; l.J.228.244; l.J.229.228; l.J.229.229; l.J.229.230; l.J.229.231; l.J.229.236; 1J.229.237; l.J.229.238; l.J.229.239; 1J.229.154; l.J.229.157; 1J.229.166; l.J.229.169; l.J.229.172; l.J.229.175; l.J.229.240; l.J.229.244; l.J.230.228; l.J.230.229; l.J.230.230; l.J.230.231; l.J.230.236; l.J.230.237; l.J.230.238; 1J.230.239; l.J.230.154; l.J.230.157; 1J.230.166; l.J.230.169; l.J.230.172; l.J.230.175; l.J.230.240; l.J.230.244; l.J.231.228; l.J.231.229; l.J.231.230; l.J.231.231; 1J.231.236; 1J.231.237; l.J.231.238; l.J.231.239; l.J.231.154; l.J.231.157; l.J.231.166; l.J.231.169; l.J.231.172; l.J.231.175; l.J.231.240; l.J.231.244; l.J.236.228; l.J.236.229; 1J.236.230; l.J.236.231; l.J.236.236; l.J.236.237; l.J.236.238; l.J.236.239; 1J.236.154; 1J.236.157; l.J.236.166; l.J.236.169; 1J.236.172; l.J.236.175; 1J.236.240; l.J.236.244; 1J.237.228; l.J.237.229; l.J.237.230; l.J.237.231; l.J.237.236; l.J.237.237; l.J.237.238; 1J.237.239; l.J.237.154; l.J.237.157; l.J.237.166; l.J.237.169; l.J.237.172; l.J.237.175; l.J.237.240; l.J.237.244; l.J.238.228; l.J.238.229; LJ.238.230; l.J.238.231; l.J.238.236; l.J.238.237; 1J.238.238; l.J.238.239; l.J.238.154; 1J.238.157; l.J.238.166; l.J.238.169; l.J.238.172; l.J.238.175; l.J.238.240; l.J.238.244; 1J.239.228; l.J.239.229; l.J.239.230; l.J.239.231; l.J.239.236; l.J.239.237; l.J.239.238; 1J.239.239; l.J.239.154; l.J.239.157; l.J.239.166; l.J.239.169; l.J.239.172; l.J.239.175; 1J.239.240; l.J.239.244; 1J.154.228; 1J.154.229; l.J.154.230; 1J.154.231; l.J.154.236; l.J.154.237; l.J.154.238; l.J.154.239; 1J.154.154; l.J.154.157; 1J.154.166; l.J.154.169; l.J.154.172; l.J.154.175; l.J.154.240; 1J.154.244; l.J.157.228; l.J.157.229; l.J.157.230; 1J.157.231; l.J.157.236; l.J.157.237; 1J.157.238; l.J.157.239; 1J.157.154; l.J.157.157; 1J.157.166; l.J.157.169; l.J.157.172; l.J.157.175; l.J.157.240; l.J.157.244; l.J.166.228; l.J.166.229; l.J.166.230; l.J.166.231; 1J.166.236; l.J.166.237; l.J.166.238; l.J.166.239; 1J.166.154; l.J.166.157; l.J.166.166; l.J.166.169; l.J.166.172; l.J.166.175; l.J.166.240; 1J.166.244; l.J.169.228; l.J.169.229; 1J.169.230; l.J.169.231; 1J.169.236; l.J.169.237; 1J.169.238; l.J.169.239; l.J.169.154; 1J.169.157; l.J.169.166; l.J.169.169; 1J.169.172; l.J.169.175; l.J.169.240; l.J.169.244; 1J.172.228; 1J.172.229; l.J.172.230; l.J.172.231; l.J.172.236; 1J.172.237; l.J.172.238; l.J.172.239; l.J.172.154; l.J.172.157; l.J.172.166; l.J.172.169; l.J.172.172; l.J.172.175; l.J.172.240; l.J.172.244; l.J.175.228; l.J.175.229; l.J.175.230; l.J.175.231; l.J.175.236; l.J.175.237; l.J.175.238; 1J.175.239; l.J.175.154; l.J.175.157; l.J.175.166; l.J.175.169; l.J.175.172; l.J.175.175; 1J.175.24Q; l.J.175.244; l.J.240.228; l.J.240.229; l.J.240.230; 1J.240.231; l.J.240.236; l.J.240.237; l.J.240.238; l.J.240.239; l.J.240.154; l.J.240.157; l.J.240.166; l.J.240.169; l.J.240.172; l.J.240.175; 1J.240.240; l.J.240.244; l.J.244.228; l.J.244.229; l.J.244.230; l.J.244.231; l.J.244.236; 1J.244.237; l.J.244.238; l.J.244.239; l.J.244.154; l.J.244.157; l.J.244.166; l.J.244.169; l.J.244.172; l.J.244.175; l.J.244.240; 1J.244.244;

Prodrugs of l.L l.L.228.228; l.L.228.229; l.L.228.230; l.L.228.231; l.L.228.236; l.L.228.237; l.L.228.238; l.L.228.239; l.L.228.154; l.L.228.157; l.L.228.166; l.L.228.169; l.L.228.172; l.L.228.175; l.L.228.240; l.L.228.244; l.L.229.228; l.L.229.229; l.L.229.230; l.L.229.231; l.L.229.236; l.L.229.237; l.L.229.238; l.L.229.239; l.L.229.154; l.L.229.157; l.L.229.166; l.L.229.169; l.L.229.172; l.L.229.175; l.L.229.240; l.L.229.244; l.L.230.228; l.L.230.229; l.L.230.230; l.L.230.231; l.L.230.236; l.L.230.237; l.L.230.238; l.L.230.239; l.L.230.154; l.L.230.157; l.L.230.166; l.L.230.169; l.L.230.172; l.L.230.175; l.L.230.240; l.L.230.244; l.L.231.228; l.L.231.229; l.L.231.230; l.L.231.231; l.L.231.236; l.L.231.237; l.L.231.238; l.L.231.239; l.L.231.154; l.L.231.157; l.L.231.166; l.L.231.169; l.L.231.172; l.L.231.175; l.L.231.240; l.L.231.244; l.L.236.228; l.L.236.229; l.L.236.230; l.L.236.231; l.L.236.236; l.L.236.237; l.L.236.238; 1X.236.239; l.L.236.154; 1X.236.157; l.L.236.166; l.L.236.169; l.L.236.172; l.L.236.175; l.L.236.240; l.L.236.244; l.L.237.228; l.L.237.229; l.L.237.230; l.L.237.231; l.L.237.236; l.L.237.237; l.L.237.238; l.L.237.239; l.L.237.154; l.L.237.157; l.L.237.166; l.L.237.169; l.L.237.172; l.L.237.175; l.L.237.240; l.L.237.244; l.L.238.228; l.L.238.229; l.L.238.230; 1X.238.231; l.L.238.236; l.L.238.237; l.L.238.238; l.L.238.239; l.L.238.154; l.L.238.157; 1X.238.166; l.L.238.169; l.L.238.172; l.L.238.175; l.L.238.240; l.L.238.244; l.L.239.228; l.L.239.229; l.L.239.230; l.L.239.231; l.L.239.236; l.L.239.237; l.L.239.238; l.L.239.239; l.L.239.154; l.L.239.157; l.L.239.166; l.L.239.169; l.L.239.172; l.L.239.175; l.L.239.240; l.L.239.244; l.L.154.228; l.L.154.229; l.L.154.230; l.L.154.231; l.L.154.236; l.L.154.237; l.L.154.238; l.L.154.239; l.L.154.154; l.L.154.157; l.L.154.166; l.L.154.169; l.L.154.172; l.L.154.175; l.L.154.240; 1. L.154.244; l.L.157.228; l.L.157.229; l.L.157.230; l.L.157.231; l.L.157.236; l.L.157.237; l.L.157.238; l.L.157.239; l.L.157.154; l.L.157.157; l.L.157.166; l.L.157.169; l.L.157.172; l.L.157.175; l.L.157.240; l.L.157.244; l.L.166.228; l.L.166.229; l.L.166.230; l.L.166.231; l.L.166.236; l.L.166.237; l.L.166.238; l.L.166.239; l.L.166.154; l.L.166.157; l.L.166.166; l.L.166.169; l.L.166.172; l.L.166.175; l.L.166.240; l.L.166.244; l.L.169.228; l.L.169.229; l.L.169.230; l.L.169.231; l.L.169.236; l.L.169.237; l.L.169.238; l.L.169.239; l.L.169.154; l.L.169.157; l.L.169.166; l.L.169.169; l.L.169.172; l.L.169.175; l.L.169.240; l.L.169.244; l.L.172.228; l.L.172.229; l.L.172.230; l.L.172.231; l.L.172.236; l.L.172.237; l.L.172.238; l.L.172.239; l.L.172.154; l.L.172.157; l.L.172.166; l.L.172.169; l.L.172.172; l.L.172.175; l.L.172.240; l.L.172.244; l.L.175.228; l.L.175.229; l.L.175.230; l.L.175.231; l.L.175.236; l.L.175.237; l.L.175.238; l.L.175.239; l.L.175.154; l.L.175.157; l.L.175.166; l.L.175.169; l.L.175.172; l.L.175.175; l.L.175.240; l.L.175.244; l.L.240.228; l.L.240.229; l.L.240.230; l.L.240.231; l.L.240.236; l.L.240.237; l.L.240.238; l.L.240.239; 1X.240.154; l.L.240.157; l.L.240.166; l.L.240.169; l.L.240.172; l.L.240.175; 1.L.240.24Q; l.L.240.244; l.L.244.228; l.L.244.229; l.L.244.230; l.L.244.231; l.L.244.236; l.L.244.237; l.L.244.238; l.L.244.239; l.L.244.154; 1X.244.157; 1X.244.166; 1X.244.169; 1X.244.172; 1X.244.175; 1X.244.240; 1X.244.244;

Prodrugs of l.O

1.O.228.228; 1.O.228.229; 1.O.228.230; 1.O.228.231; 1.O.228.236; 1.O.228.237; 1.O.228.238; 1.O.228.239; 1.O.228.154; 1.O.228.157; 1.O.228.166; 1.O.228.169; 1.O.228.172; 1.O.228.175; 1.O.228.240; 1.O.228.244; 1.O.229.228; 1.O.229.229; 1.O.229.230; 1.O.229.231; 1.O.229.236; 1.O.229.237; 1.O.229.238; 1.O.229.239; 1.O.229.154; 1.O.229.157; 1.O.229.166; 1.O.229.169; 1.O.229.172; 1.O.229.175; 1.O.229.240; 1.O.229.244; 1.O.230.228; 1.O.230.229; 1.O.230.230; 1.O.230.231; 1.O.230.236; 1.O.230.237; 1.O.230.238; 1.O.230.239; 1.O.230.154; 1.O.230.157; 1.O.230.166; 1.O.230.169; 1.O.230.172; 1.O.230.175; 1.O.230.240; 1.O.230.244; 1.O.231.228; 1.O.231.229; 1.O.231.230; 1.O.231.231; 1.O.231.236; 1.O.231.237; 1.O.231.238; 1.O.231.239; 1.O.231.154; 1.O.231.157; 1.O.231.166; 1.O.231.169; 1.O.231.172; 1.O.231.175; 1.O.231.240; 1.O.231.244; 1.O.236.228; 1.O.236.229; 1.O.236.230; 1.O.236.231; 1.O.236.236; 1.O.236.237; 1.O.236.238; 1.O.236.239; 1.O.236.154; 1.O.236.157; 1.O.236.166; 1.O.236.169; 1.O.236.172; 1.O.236.175; 1.O.236.240; 1.O.236.244; 1.O.237.228; 1.O.237.229; 1.O.237.230; 1.O.237.231; 1.O.237.236; 1.O.237.237; 1.O.237.238; 1.O.237.239; 1.O.237.154; 1.O.237.157; 1.O.237.166; 1.O.237.169; 1.O.237.172; 1.O.237.175; 1.O.237.240; 1.O.237.244; 1.O.238.228; 1.O.238.229; 1.O.238.230; 1.O.238.231; 1.O.238.236; 1.O.238.237; 1.O.238.238; 1.O.238.239; 1.O.238.154; 1.O.238.157; 1.O.238.166; 1.O.238.169; 1.O.238.172; 1.O.238.175; 1.O.238.240; 1.O.238.244; 1.O.239.228; 1.O.239.229; 1.O.239.230; 1.O.239.231; 1.0.239.236; 1.O.239.237; 1.O.239.238; 1.O.239.239; 1.O.239.154; 1.O.239.157; 1.O.239.166; 1.O.239.169; 1.O.239.172; 1.O.239.175; 1.O.239.240; 1.O.239.244; 1.O.154.228; 1.O.154.229; 1.O.154.230; 1.O.154.231; 1.O.154.236; 1.O.154.237; 1.O.154.238; 1.O.154.239; 1.O.154.154; 1.O.154.157; 1.O.154.166; 1.O.154.169; 1.0.154.172; 1.O.154.175; 1.O.154.240; 1.O.154.244; 1.O.157.228; 1.O.157.229; 1.O.157.230; 1.O.157.231; 1.O.157.236; 1.O.157.237; 1.O.157.238; 1.O.157.239; 1.O.157.154; 1.O.157.157; 1.O.157.166; 1.O.157.169; 1.O.157.172; 1.O.157.175; 1.O.157.240; 1.O.157.244; 1.O.166.228; 1.O.166.229; 1.O.166.230; 1.O.166.231; 1.O.166.236; 1.O.166.237; 1.O.166.238; 1.O.166.239; 1.O.166.154; 1.O.166.157; 1.0-166.166; 1.O.166.169; 1.O.166.172; 1.O.166.175; 1.O.166.240; 1.O.166.244; 1.O.169.228; 1.O.169.229; 1.O.169.230; 1.O.169.231; 1.O.169.236; 1.O.169.237; 1.O.169.238; 1.O.169.239; 1.O.169.154; 1.O.169.157; 1.O.169.166; 1.O.169.169; 1.O.169.172; 1.O.169.175; 1.O.169.240; 1.O.169.244; 1.O.172.228; 1.O.172.229; 1.O.172.230; 1.O.172.231; 1.O.172.236; 1.O.172.237; 1.O.172.238; 1.O.172.239; 1.O.172.154; 1.O.172.157; 1.O.172.166; 1.O.172.169; 1.O.172.172; 1.O.172.175; 1.O.172.240; 1.O.172.244; 1.O.175.228; 1.O.175.229; 1.O.175.230; 1.O.175.231; 1.O.175.236; 1.O.175.237; 1.O.175.238; 1.O.175.239; 1.O.175.154; 1.O.175.157; 1.O.175.166; 1.O.175.169; 1.O.175.172; 1.O.175.175; 1.O.175.240; 1.O.175.244; 1.O.240.228; 1.O.240.229; 1.O.240.230; 1.O.240.231; 1.O.240.236; 1.O.240.237; 1.O.240.238; 1.O.240.239; 1.O.240.154; 1.O.240.157; 1.O.240.166; 1.O.240.169; 1.O.240.172; 1.O.240.175; 1.O.240.240; 1.O.240.244; 1.O.244.228; 1.O.244.229; 1.O.244.230; 1.O.244.231; 1.O.244.236; 1.O.244.237; 1.O.244.238; 1.O.244.239; 1.O.244.154; 1.O.244.157; 1.O.244.166; 1.O.244.169; 1.O.244.172; 1.O.244.175; 1.O.244.240; 1.O.244.244;

Prodrugs of l.P l.P.228.228; l.P.228.229; l.P.228.230; l.P.228.231; l.P.228.236; l.P.228.237; l.P.228.238; l.P.228.239; l.P.228.154; l.P.228.157; l.P.228.166; l.P.228.169; l.P.228.172; l.P.228.175; l.P.228.240; l.P.228.244; l.P.229.228; l.P.229.229; l.P.229.230; l.P.229.231; l.P.229.236; l.P.229.237; l.P.229.238; l.P.229.239; l.P.229.154; l.P.229.157; l.P.229.166; l.P.229.169; l.P.229.172; l.P.229.175; l.P.229.240; l.P.229.244; l.P.230.228; l.P.230.229; l.P.230.230; l.P.230.231; l.P.230.236; l.P.230.237; l.P.230.238; l.P.230.239; l.P.230.154; l.P.230.157; l.P.230.166; l.P.230.169; l.P.230.172; l.P.230.175; l.P.230.240; l.P.230.244; l.P.231.228; l.P.231.229; l.P.231.230; l.P.231.231; l.P.231.236; l.P.231.237; l.P.231.238; l.P.231.239; l.P.231.154; l.P.231.157; l.P.231.166; l.P.231.169; l.P.231.172; l.P.231.175; l.P.231.240; l.P.231.244; l.P.236.228; l.P.236.229; l.P.236.230; l.P.236.231; l.P.236.236; l.P.236.237; l.P.236.238; l.P.236.239; l.P.236.154; l.P.236.157; l.P.236.166; l.P.236.169; l.P.236.172; l.P.236.175; l.P.236.240; l.P.236.244; l.P.237.228; l.P.237.229; l.P.237.230; l.P.237.231; l.P.237.236; l.P.237.237; l.P.237.238; l.P.237.239; l.P.237.154; l.P.237.157; l.P.237.166; l.P.237.169; l.P.237.172; l.P.237.175; l.P.237.240; l.P.237.244; l.P.238.228; l.P.238.229; l.P.238.230; l.P.238.231; l.P.238.236; l.P.238.237; l.P.238.238; l.P.238.239; l.P.238.154; l.P.238.157; l.P.238.166; l.P.238.169; l.P.238.172; l.P.238.175; l.P.238.240; l.P.238.244; l.P.239.228; l.P.239.229; l.P.239.230; l.P.239.231; l.P.239.236; l.P.239.237; l.P.239.238; l.P.239.239; l.P.239.154; l.P.239.157; l.P.239.166; l.P.239.169; l.P.239.172; l.P.239.175; l.P.239.240; l.P.239.244; l.P.154.228; l.P.154.229; l.P.154.230; l.P.154.231; l.P.154.236; l.P.154.237; l.P.154.238; l.P.154.239; l.P.154.154; l.P.154.157; l.P.154.166; l.P.154.169; l.P.154.172; l.P.154.175; l.P.154.240; l.P.154.244; l.P.157.228; l.P.157.229; l.P.157.230; l.P.157.231; l.P.157.236; l.P.157.237; l.P.157.238; l.P.157.239; l.P.157.154; l.P.157.157; l.P.157.166; l.P.157.169; l.P.157.172; l.P.157.175; l.P.157.240; l.P.157.244; l.P.166.228; l.P.166.229; l.P.166.230; l.P.166.231; l.P.166.236; l.P.166.237; l.P.166.238; l.P.166.239; l.P.166.154; l.P.166.157; l.P.166.166; l.P.166.169; l.P.166.172; l.P.166.175; l.P.166.240; l.P.166.244; l.P.169.228; l.P.169.229; l.P.169.230; l.P.169.231; l.P.169.236; l.P.169.237; l.P.169.238; l.P.169.239; l.P.169.154; l.P.169.157; l.P.169.166; l.P.169.169; l.P.169.172; l.P.169.175; l.P.169.240; l.P.169.244; l.P.172.228; l.P.172.229; l.P.172.230; l.P.172.231; l.P.172.236; l.P.172.237; l.P.172.238; l.P.172.239; l.P.172.154; l.P.172.157; 1..P '.172.166; l.P.172.169; l.P.172.172; l.P.172.175; l.P.172.240; l.P.172.244; l.P.175.228; l.P.175.229; l.P.175.230; l.P.175.231; l.P.175.236; l.P.175.237; l.P.175.238; l.P.175.239; l.P.175.154; l.P.175.157; l.P.175.166; l.P.175.169; l.P.175.172; l.P.175.175; l.P.175.240; l.P.175.244; l.P.240.228; l.P.240.229; l.P.240.230; l.P.240.231; l.P.240.236; l.P.240.237; l.P.240.238; l.P.240.239; l.P.240.154; l.P.240.157; l.P.240.166; l.P.240.169; l.P.240.172; l.P.240.175; l.P.240.240; l.P.240.244; l.P.244.228; l.P.244.229; l.P.244.230; l.P.244.231; l.P.244.236; l.P.244.237; l.P.244.238; l.P.244.239; l.P.244.154; l.P.244.157; l.P.244.166; l.P.244.169; l.P.244.172; l.P.244.175; l.P.244.240; l.P.244.244;

Prodrugs of LU l.U.228.228; l.U.228.229; l.U.228.230; l.U.228.231; l.U.228.236; l.U.228.237; l.U.228.238; l.U.228.239; l.U.228.154; l.U.228.157; l.U.228.166; l.U.228.169; l.U.228.172; l.U.228.175; l.U.228.240; l.U.228.244; l.U.229.228; l.U.229.229; l.U.229.230; l.U.229.231; l.U.229.236; l.U.229.237; l.U.229.238; l.U.229.239; l.U.229.154; l.U.229.157; l.U.229.166; l.U.229.169; l.U.229.172; l.U.229.175; l.U.229.240; l.U.229.244; l.U.230.228; l.U.230.229; l.U.230.230; l.U.230.231; l.U.230.236; l.U.230.237; l.U.230.238; l.U.230.239; l.U.230.154; l.U.230.157; l.U.230.166; l.U.230.169; l.U.230.172; l.U.230.175; l.U.230.240; l.U.230.244; l.U.231.228; l.U.231.229; l.U.231.230; l.U.231.231; l.U.231.236; l.U.231.237; l.U.231.238; l.U.231.239; l.U.231.154; l.U.231.157; l.U.231.166; l.U.231.169; l.U.231.172; l.U.231.175; l.U.231.240; l.U.231.244; l.U.236.228; l.U.236.229; l.U.236.230; l.U.236.231; l.U.236.236; l.U.236.237; l.U.236.238; l.U.236.239; l.U.236.154; l.U.236.157; l.U.236.166; l.U.236.169; l.U.236.172; l.U.236.175; l.U.236.240; l.U.236.244; l.U.237.228; l.U.237.229; l.U.237.230; l.U.237.231; l.U.237.236; l.U.237.237; l.U.237.238; l.U.237.239; l.U.237.154; l.U.237.157; l.U.237.166; l.U.237.169; l.U.237.172; l.U.237.175; l.U.237.240; l.U.237.244; l.U.238.228; l.U.238.229; l.U.238.230; l.U.238.231; l.U.238.236; l.U.238.237; l.U.238.238; l.U.238.239; l.U.238.154; l.U.238.157; l.U.238.166; l.U.238.169; l.U.238.172; l.U.238.175; l.U.238.240; l.U.238.244; l.U.239.228; l.U.239.229; l.U.239.230; l.U.239.231; l.U.239.236; l.U.239.237; l.U.239.238; l.U.239.239; l.U.239.154; l.U.239.157; l.U.239.166; l.U.239.169; l.U.239.172; l.U.239.175; l.U.239.240; l.U.239.244; l.U.154.228; l.U.154.229; l.U.154.230; l.U.154.231; l.U.154.236; l.U.154.237; l.U.154.238; l.U.154.239; l.U.154.154; l.U.154.157; l.U.154.166; l.U.154.169; l.U.154.172; l.U.154.175; l.U.154.240; l.U.154.244; l.U.157.228; l.U.157.229; l.U.157.230; l.U.157.231; l.U.157.236; l.U.157.237; l.U.157.238; l.U.157.239; l.U.157.154; l.U.157.157; l.U.157.166; l.U.157.169; l.U.157.172; l.U.157.175; l.U.157.240; l.U.157.244; l.U.166.228; l.U.166.229; l.U.166.230; l.U.166.231; l.U.166.236; l.U.166.237; l.U.166.238; l.U.166.239; l.U.166.154; l.U.166.157; l.U.166.166; l.U.166.169; l.U.166.172; l.U.166.175; l.U.166.240; l.U.166.244; l.U.169.228; l.U.169.229; l.U.169.230; l.U.169.231; l.U.169.236; l.U.169.237; l.U.169.238; l.U.169.239; l.U.169.154; l.U.169.157; l.U.169.166; l.U.169.169; l.U.169.172; l.U.169.175; l.U.169.240; l.U.169.244; l.U.172.228; l.U.172.229; l.U.172.230; l.U.172.231; l.U.172.236; l.U.172.237; l.U.172.238; l.U.172.239; l.U.172.154; l.U.172.157; l.U.172.166; l.U.172.169; l.U.172.172; l.U.172.175; l.U.172.240; l.U.172.244; l.U.175.228; l.U.175.229; l.U.175.230; l.U.175.231; l.U.175.236; l.U.175.237; l.U.175.238; l.U.175.239; l.U.175.154; l.U.175.157; l.U.175.166; l.U.175.169; l.U.175.172; l.U.175.175; l.U.175.240; l.U.175.244; l.U.240.228; l.U.240.229; l.U.240.230; l.U.240.231; l.U.240.236; l.U.240.237; 1.U.24Q.238; l.U.240.239; l.U.240.154; l.U.240.157; l.U.240.166; l.U.240.169; 1.U.24Q.172; l.U.240.175; l.U.240.240; l.U.240.244; l.U.244.228; l.U.244.229; l.U.244.230; l.U.244.231; l.U.244.236; l.U.244.237; l.U.244.238; l.U.244.239; l.U.244.154; l.U.244.157; l.U.244.166; l.U.244.169; l.U.244.172; l.U.244.175; l.U.244.240; l.U.244.244;

Prodrugs of LCD l.CD.228.228; l.CD.228.229; l.CD.228.230; l.CD.228.231; l.CD.228.236; l.CD.228.237; l.CD.228.238; l.CD.228.239; l.CD.228.154; l.CD.228.157; l.CD.228.166; l.CD.228.169; l.CD.228.172; l.CD.228.175; l.CD.228.240; l.CD.228.244; l.CD.229.228; l.CD.229.229; l.CD.229.230; I. CD.229.231; l.CD.229.236; l.CD.229.237; l.CD.229.238; l.CD.229.239; l.CD.229.154; l.CD.229.157; 1. CD.229.166; l.CD.229.169; l.CD.229.172; l.CD.229.175; l.CD.229.240; l.CD.229.244; l.CD.230.228; l.CD.230.229; l.CD.230.230; l.CD.230.231; l.CD.230.236; l.CD.230.237; l.CD.230.238; l.CD.230.239; l.CD.230.154; l.CD.230.157; l.CD.230.166; l.CD.230.169; l.CD.230.172; l.CD.230.175; l.CD.230.240; l.CD.230.244; l.CD.231.228; l.CD.231.229; l.CD.231.230; l.CD.231.231; l.CD.231.236; l.CD.231.237; l.CD.231.238; l.CD.231.239; l.CD.231.154; l.CD.231.157; l.CD.231.166; l.CD.231.169; l.CD.231.172; l.CD.231.175; l.CD.231.240; 1. CD.231.2AA; l.CD.236.228; l.CD.236.229; l.CD.236.230; l.CD.236.231; l.CD.236.236; l.CD.236.237; l.CD.236.238; l.CD.236.239; l.CD.236.154; 1. CD.236.157; 1. CD.236.166; l.CD.236.169; l.CD.236.172; l.CD.236.175; l.CD.236.240; l.CD.236.244; l.CD.237.228; l.CD.237.229; l.CD.237.230; l.CD.237.231; l.CD.237.236; l.CD.237.237; l.CD.237.238; l.CD.237.239; l.CD.237.154; l.CD.237.157; l.CD.237.166; l.CD.237.169; l.CD.237.172; 1. CD.237.175; l.CD.237.240; l.CD.237.244; l.CD.238.228; l.CD.238.229; l.CD.238.230; l.CD.238.231; l.CD.238.236; l.CD.238.237; l.CD.238.238; l.CD.238.239; l.CD.238.154; l.CD.238.157; l.CD.238.166; l.CD.238.169; l.CD.238.172; l.CD.238.175; l.CD.238.240; l.CD.238.244; l.CD.239.228; 1. CD.239.229; l.CD.239.230; l.CD.239.231; l.CD.239.236; l.CD.239.237; l.CD.239.238; l.CD.239.239; l.CD.239.154; l.CD.239.157; l.CD.239.166; l.CD.239.169; l.CD.239.172; l.CD.239.175; l.CD.239.240; l.CD.239.244; l.CD.154.228; l.CP.154.229; l.CD.154.230; l.CD.154.231; l.CD.154.236; l.CD.154.237; l.CD.154.238; l.CD.154.239; l.CD.154.154; l.CD.154.157; l.CD.154.166; l.CD.154.169; l.CD.154.172; l.CD.154.175; l.CD.154.240; l.CD.154.244; LCD.157.228; l.CD.157.229; l.CD.157.230; l.CD.157.231; l.CD.157.236; 1. CD.157.237; l.CD.157.238; l.CD.157.239; l.CD.157.154; l.CD.157.157; l.CD.157.166; l.CD.157.169; l.CD.157.172; l.CD.157.175; l.CD.157.240; l.CD.157.244; l.CD.166.228; l.CD.166.229; l.CD.166.230; l.CD.166.231; l.CD.166.236; l.CD.166.237; l.CD.166.238; l.CD.166.239; l.CD.166.154; l.CD.166.157; l.CD.166.166; LCD.166.169; l.CD.166.172; l.CD.166.175; 1.CD.166.24Q; l.CD.166.244; l.CD.169.228; l.CD.169.229; l.CD.169.230; l.CD.169.231; l.CD.169.236; l.CD.169.237; l.CD.169.238; l.CD.169.239; l.CD.169.154; l.CD.169.157; l.CD.169.166; l.CD.169.169; l.CD.169.172; LCD.169.175; l.CD.169.240; l.CD.169.244; l.CD.172.228; l.CD.172.229; l.CD.172.230; l.CD.172.231; l.CD.172.236; l.CD.172.237; l.CD.172.238; l.CD.172.239; l.CD.172.154; l.CD.172.157; l.CD.172.166; l.CD.172.169; l.CD.172.172; l.CD.172.175; l.CP.172.240; l.CD.172.244; l.CD.175.228; l.CD.175.229; l.CD.175.230; l.CD.175.231; l.CD.175.236; l.CD.175.237; l.CD.175.238; l.CD.175.239; l.CD.175.154; l.CD.175.157; l.CD.175.166; l.CD.175.169; l.CD.175.172; l.CD.175.175; l.CD.175.240; l.CD.175.244; l.CD.240.228; l.CD.240.229; l.CD.240.230; l.CD.240.231; l.CD.240.236; l.CD.240.237; l.CD.240.238; l.CD.240.239; l.CD.240.154; l.CD.240.157; l.CD.240.166; l.CD.240.169; l.CD.240.172; l.CD.240.175; l.CD.240.240; l.CD.240.244; l.CD.244.228; l.CD.244.229; l.CD.244.230; l.CD.244.231; l.CD.244.236; l.CD.244.237; l.CD.244.238; l.CD.244.239; l.CD.244.154; l.CD.244.157; l.CD.244.166; l.CD.244.169; l.CD.244.172; l.CD.244.175; l.CD.244.240; l.CD.244.244;

Prodrugs of l.EB l.EB.228.228; l.EB.228.229; l.EB.228.230; l.EB.228.231; l.EB.228.236; l.EB.228.237; l.EB.228.238; l.EB.228.239; l.EB.228.154; l.EB.228.157; l.EB.228.166; l.EB.228.169; l.EB.228.172; l.EB.228.175; l.EB.228.240; l.EB.228.244; l.EB.229.228; l.EB.229.229; l.EB.229.230; l.EB.229.231; l.EB.229.236; l.EB.229.237; l.EB.229.238; l.EB.229.239; l.EB.229.154; l.EB.229.157; l.EB.229.166; l.EB.229.169; l.EB.229.172; l.EB.229.175; l.EB.229.240; l.EB.229.244; l.EB.230.228; l.EB.230.229; l.EB.230.230; l.EB.230.231; l.EB.230.236; l.EB.230.237; l.EB.230.238; l.EB.230.239; l.EB.230.154; l.EB.230.157; l.EB.230.166; l.EB.230.169; l.EB.230.172; l.EB.230.175; l.EB.230.240; l.EB.230.244; l.EB.231.228; l.EB.231.229; l.EB.231.230; l.EB.231.231; l.EB.231.236; l.EB.231.237; l.EB.231.238; l.EB.231.239; l.EB.231.154; l.EB.231.157; l.EB.231.166; l.EB.231.169; l.EB.231.172; l.EB.231.175; l.EB.231.240; l.EB.231.244; l.EB.236.228; l.EB.236.229; l.EB.236.230; l.EB.236.231; l.EB.236.236; l.EB.236.237; l.EB.236.238; l.EB.236.239; l.EB.236.154; l.EB.236.157; l.EB.236.166; l.EB-236.169; l.EB.236.172; l.EB.236.175; l.EB.236.240; l.EB.236.244; l.EB.237.228; l.EB.237.229; l.EB.237.230; l.EB.237.231; l.EB.237.236; l.EB.237.237; l.EB.237.238; l.EB.237.239; l.EB.237.154; l.EB.237.157; l.EB.237.166; l.EB.237.169; l.EB.237.172; l.EB.237.175; l.EB.237.240; l.EB.237.244; l.EB.238.228; l.EB.238.229; l.EB.238.230; l.EB.238.231; l.EB.238.236; l.EB.238.237; l.EB.238.238; l.EB.238.239; l.EB.238.154; l.EB.238.157; l.EB.238.166; l.EB.238.169; l.EB.238.172; l.EB.238.175; l.EB.238.240; l.EB.238.244; l.EB.239.228; l.EB.239.229; l.EB.239.230; l.EB.239.231; l.EB.239.236; l.EB.239.237; l.EB.239.238; l.EB.239.239; l.EB.239.154; l.EB.239.157; l.EB.239.166; l.EB.239.169; l.EB.239.172; l.EB.239.175; l.EB.239.240; l.EB.239.244; l.EB.154.228; l.EB.154.229; l.EB.154.230; l.EB.154.231; l.EB.154.236; l.EB.154.237; l.EB.154.238; l.EB.154.239; l.EB.154.154; l.EB.154.157; l.EB.154.166; l.EB.154.169; l.EB.154.172; l.EB.154.175; l.EB.154.240; l.EB.154.244; l.EB.157.228; l.EB.157.229; l.EB.157.230; l.EB.157.231; l.EB.157.236; l.EB.157.237; l.EB.157.238; l.EB.157.239; l.EB.157.154; l.EB.157.157; l.EB.157.166; l.EB.157.169; l.EB.157.172; l.EB.157.175; 1.EB.157.24Q; l.EB.157.244; l.EB.166.228; l.EB.166.229; l.EB.166.230; l.EB.166.231; l.EB.166.236; l.EB.166.237; l.EB.166.238; l.EB.166.239; l.EB.166.154; l.EB.166.157; l.EB.166.166; l.EB.166.169; l.EB.166.172; l.EB.166.175; l.EB.166.240; l.EB.166.244; l.EB.169.228; l.EB.169.229; l.EB.169.230; l.EB.169.231; l.EB.169.236; l.EB.169.237; l.EB.169.238; l.EB.169.239; l.EB.169.154; l.EB.169.157; l.EB.169.166; l.EB.169.169; l.EB.169.172; l.EB.169.175; l.EB.169.240; l.EB.169.244; l.EB.172.228; l.EB.172.229; l.EB.172.230; l.EB.172.231; l.EB.172.236; l.EB.172.237; l.EB.172.238; l.EB.172.239; l.EB.172.154; l.EB.172.157; l.EB.172.166; l.EB.172.169; l.EB.172.172; l.EB.172.175; l.EB.172.240; l.EB.172.244; l.EB.175.228; l.EB.175.229; l.EB.175.230; l.EB.175.231; l.EB.175.236; l.EB.175.237; l.EB.175.238; l.EB.175.239; l.EB.175.154; l.EB.175.157; l.EB.175.166; l.EB.175.169; l.EB.175.172; l.EB.175.175; l.EB.175.240; l.EB.175.244; l.EB.240.228; l.EB.240.229; l.EB.240.230; l.EB.240.231; l.EB.240.236; l.EB.240.237; l.EB.240.238; l.EB.240.239; l.EB.240.154; l.EB.240.157; l.EB.240.166; l.EB.240.169; l.EB.240.172; l.EB.240.175; l.EB.240.240; l.EB.240.244; l.EB.244.228; l.EB.244.229; l.EB.244.230; l.EB.244.231; l.EB.244.236; l.EB.244.237; l.EB.244.238; l.EB.244.239; l.EB.244.154; l.EB.244.157; l.EB.244.166; l.EB.244.169; l.EB.244.172; l.EB.244.175; l.EB.244.240; l.EB.244.244;

Prodrugs of 2.B

2.B.228.228; 2.B.228.229; 2.B.228.230; 2.B.228.231; 2.B.228.236; 2.B.228.237; 2.B.228.238; 2.B.228.239; 2.B.228.154; 2.B.228.157; 2.B.228.166; 2.B.228.169; 2.B.228.172; 2.B.228.175; 2.B.228.240; 2.B.228.244; 2.B.229.228; 2.B.229.229; 2.B.229.230; 2.B.229.231; 2.B.229.236; 2.B.229.237; 2.B.229.238; 2.B.229.239; 2.B.229.154; 2.B.229.157; 2.B.229.166; 2.B.229.169; 2.B.229.172; 2.B.229.175; 2.B.229.240; 2.B.229.244; 2.B.230.228; 2.B.230.229; 2.B.230.230; 2.B.230.231; 2.B.230.236; 2.B.230.237; 2.B.230.238; 2.B.230.239; 2.B.230.154; 2.B.230.157; 2.B.230.166; 2.B.230.169; 2.B.23Q.172; 2.B.230.175; 2.B.230.240; 2.B.230.244; 2.B.231.228; 2.B.231.229; 2.B.231.230; 2.B.231.231; 2.B.231.236; 2.B.231.237; 2.B.231.238; 2.B.231.239; 2.B.231.154; 2.B.231.157; 2.B.231.166; 2.B.231.169; 2.B.231.172; 2.B.231.175; 2.B.231.240; 2.B.231.244; 2.B.236.228; 2.B.236.229; 2.B.236.230; 2.B.236.231; 2.B.236.236; 2.B.236.237; 2.B.236.238; 2.B.236.239; 2.B.236.154; 2.B.236.157; 2.B.236.166; 2.B.236.169; 2.B.236.172; 2.B.236.175; 2.B.236.240; 2.B.236.244; 2.B.237.228; 2.B.237.229; 2.B.237.230; 2.B.237.231; 2.B.237.236; 2.B.237.237; 2.B.237.238; 2.B.237.239; 2.B.237.154; 2.B.237.157; 2.B.237.166; 2.B.237.169; 2.B.237.172; 2.B.237.175; 2.B.237.240; 2.B.237.244; 2.B.238.228; 2.B.238.229; 2.B.238.230; 2.B.238.231; 2.B.238.236; 2.B.238.237; 2.B.238.238; 2.B.238.239; 2.B.238.154; 2.B.238.157; 2.B.238.166; 2.B.238.169; 2.B.238.172; 2.B.238.175; 2.B.238.240; 2.B.238.244; 2.B.239.228; 2.B.239.229; 2.B.239.230; 2.B.239.231; 2.B.239.236; 2.B.239.237; 2.B.239.238; 2.B.239.239; 2.B.239.154; 2.B.239.157; 2.B.239.166; 2.B.239.169; 2.B.239.172; 2.B.239.175; 2.B.239.240; 2.B.239.244; 2.B.154.228; 2.B.154.229; 2.B.1S4.230; 2.B.154.231; 2.B.154.236; 2.B.154.237; 2.B.154.238; 2.B.154.239; 2.B.154.154; 2.B.154.157; 2.B.154.166; 2.B.154.169; 2.B.154.172; 2.B.154.175; 2.B.154.240; 2.B.154.244; 2.B.157.228; 2.B.157.229; 2.B.157.230; 2.B.157.231; 2.B.157.236; 2.B.157.237; 2.B.157.238; 2.B.157.239; 2.B.157.154; 2.B.157.157; 2.B.157.166; 2.B.157.169; 2.B.157.172; 2.B.157.175; 2.B.157.240; 2.B.157.244; 2.B.166.228; 2.B.166.229; 2.B.166.23Q; 2.B.166.231; 2.B.166.236; 2.B.166.237; 2.B.166.238; 2.B.166.239; 2.B.166.154; 2.B.166.157; 2.B.166.166; 2.B.166.169; 2.B.166.172; 2.B.166.175; 2.B.166.240; 2.B.166.244; 2.B.169.228; 2.B.169.229; 2.B.169.230; 2.B.169.231; 2.B.169.236; 2.B.169.237; 2.B.169.238; 2.B.169.239; 2.B.169.154; 2.B.169.157; 2.B.169.166; 2.B.169.169; 2.B.169.172; 2.B.169.175; 2.B.169.240; 2.B.169.244; 2.B.172.228; 2.B.172.229; 2.B.172.230; 2.B.172.231; 2.B.172.236; 2.B.172.237; 2.B.172.238; 2.B.172.239; 2.B.172.154; 2.B.172.157; 2.B.172.166; 2.B.172.169; 2.B.172.172; 2.B.172.175; 2.B.172.240; 2.B.172.244; 2.B.175.228; 2.B.175.229; 2.B.175.230; 2.B.175.231; 2.B.175.236; 2.B.175.237; 2.B.175.238; 2.B.175.239; 2.B.175.154; 2.B.175.157; 2.B.175.166; 2.B.175.169; 23.175.172; 23.175.175; 2.B.175.240; 2.B.175.244; 2.B.240.228; 2.B.240.229; 2.B.240.230; 2.B.240.231; 2.B.240.236; 2.B.240.237; 2.B.240.238; 2.B.240.239; 2.B.240.154; 2.B.240.157; 2.B.240.166; 2.B.240.169; 2.B.240.172; 2.B.240.175; 2.B.240.240; 2.B.240.244; 2.B.244.228; 2.B.244.229; 2.B.244.230; 2.B.244.231; 2.B.244.236; 2.B.244.237; 2.B.244.238; 2.B.244.239; 2.B.244.154; 2.B.244.157; 2.B.244.166; 2.B.244.169; 2.B.244.172; 2.B.244.175; 2.B.244.240; 2.B.244.244;

Prodrugs of 2.D

2.D.228.228; 2.D.228.229; 2.D.228.230; 2.D.228.231; 2.D.228.236; 2.D.228.237; 2.D.228.238; 2.D.228.239; 2.D.228.154; 2.D.228.157; 2.D.228.166; 2.D.228.169; 2.D.228.172; 2.D.228.175; 2.D.228.240; 2.D.228.244; 2.D.229.228; 2.D.229.229; 2.D.229.230; 2.D.229.231; 2.D.229.236; 2.D.229.237; 2.D.229.238; 2.D.229.239; 2.P.229.154; 2.D.229.157; 2.D.229.166; 2.D.229.169; 2.D.229.172; 2.D.229.175; 2.D.229.240; 2.D.229.244; 2.D.230.228; 2.D.230.229; 2.D.230.230; 2.D.230.231; 2.D.230.236; 2.D.230-237; 2.D.230.238; 2.D.230.239; 2.D.230.154; 2.D.230.157; 2.D.230.166; 2.D.230.169; 2.D.230.172; 2.D.230.175; 2.D.230.240; 2.D.230.244; 2.D.231.228; 2.D.231.229; 2.D.231.230; 2.D.231.231; 2.D.231.236; 2.D.231.237; 2.P.231.238; 2.D.231.239; 2.D.231.154; 2.D.231.157; 2.D.231.166; 2.D.231.169; 2.D.231.172; 2.D.231.175; 2.D.231.240; 2.D.231.244; 2.D.236.228; 2.D.236.229; 2.D.236.230; 2.D.236.231; 2.D.236.236; 2.D.236.237; 2.D.236.238; 2.D.236.239; 2.D.236.154; 2.D.236.157; 2.D.236.166; 2.D.236.169; 2.D.236.172; 2.D.236.175; 2.D.236.240; 2.D.236.244; 2.D.237.228; 2.D.237.229; 2.D.237.230; 2.D.237.231; 2.D.237.236; 2.D.237.237; 2.D.237.238; 2.D.237.239; 2.D.237.154; 2.D.237.157; 2.D.237.166; 2.D.237.169; 2.D.237.172; 2.D.237.175; 2.D.237.240; 2.D.237.244; 2.D.238.228; 2.D.238.229; 2.D.238.230; 2.D.238.231; 2.D.238.236; 2.D.238.237; 2.D.238.238; 2.D.238.239; 2.D.238.154; 2.D.238-157; 2.D.238.166; 2.D.238.169; 2.D.238.172; 2.D.238.175; 2.D.238.240; 2.D.238.244; 2.D.239.228; 2.D.239.229; 2.D.239.230; 2.D.239.231; 2.D.239.236; 2.D.239.237; 2.D.239.238; 2.D.239.239; 2.D.239.154; 2.D.239.157; 2.D.239.166; 2.D.239.169; 2.D.239.172; 2.D.239.175; 2.D.239.240; 2.D.239.244; 2.D.154.228; 2.D.154.229; 2.D.154.230; 2.D.154.231; 2.D.154.236; 2.D.154.237; 2.D.154.238; 2.D.154.239; 2.D.154.154; 2.D.154.157; 2.D.154.166; 2.D.154.169; 2.D.154.172; 2.D.154.175; 2.D.154.240; 2.D.154.244; 2.D.157.228; 2.D.157.229; 2.D.157.230; 2.D.157.231; 2.D.157.236; 2.D.157.237; 2.D.157.238; 2.D.157.239; 2.D.157.154; 2.D.157.157; 2.D.157.166; 2.D.157.169; 2.D.157.172; 2.D.157.175; 2.D.157.240; 2.D.157.244; 2.D.166.228; 2.D.166.229; 2.D.166.230; 2.D.166.231; 2.D.166-236; 2.D.166.237; 2.D.166.238; 2.D.166.239; 2.D.166.154; 2.D.166.157; 2.D.166.166; 2.D.166.169; 2.D.166.172; 2.D.166.175; 2.D.166.240; 2.D.166.244; 2.D.169.228; 2.D.169.229; 2.D.169.230; 2.D.169.231; 2.D.169.236; 2.D.169.237; 2.P.169.238; 2.D.169.239; 2.D.169.154; 2.D.169.157; 2.D.169.166; 2.D.169.169; 2.D.169.172; 2.D.169.175; 2.D.169.240; 2.D.169.244; 2.D.172.228; 2.D.172.229; 2.D.172.230; 2.D.172.231; 2.D.172.236; 2.D.172.237; 2.D.172.238; 2.D.172.239; 2.D.172.154; 2.D.172.157; 2.D.172.166; 2.D.172.169; 2.D.172.172; 2.D.172.175; 2.D.172.240; 2.D.172.244; 2.D.175.228; 2.D.175.229; 2.D.175.230; 2.D.175.231; 2.D.175.236; 2.D.175.237; 2.D.175.238; 2.D.175.239; 2.D.175.154; 2.D.175.157; 2.D.175.166; 2.D.175.169; 2.D.175.172; 2.D.175.175; 2.D.175.240; 2.D.175.244; 2.D.240.228; 2.D.240.229; 2.D.240.230; 2.D.240.231; 2.D.240.236; 2.D.240.237; 2.D.240.238; 2.D.240.239; 2.D.240.154; 2.D.240.157; 2.D.240.166; 2.D.240.169; 2.D.240.172; 2.D.240.175; 2.D.240.240; 2.D.240.244; 2.D.244.228; 2.D.244.229; 2.D.244.230; 2.D.244.231; 2.D.244.236; 2.D.244.237; 2.D.244.238; 2.D.244.239; 2.D.244.154; 2.D.244.157; 2.D.244.166; 2.D.244.169; 2.D.244.172; 2.D.244.175; 2.D.244.240; 2.D.244.244;

Prodrugs of 2.AB

2.AB.228.228; 2.AB.228.229; 2.AB.228.230; 2.AB.228.231; 2.AB.228.236; 2.AB.228.237; 2.AB.228.238; 2.AB.228.239; 2.AB.228.154; 2.AB.228.157; 2.AB.228.166; 2.AB.228.169; 2.AB.228.172; 2.AB.228.175; 2.AB.228.240; 2.AB.228.244; 2.AB.229.228; 2.AB.229.229; 2.AB.229.230; 2.AB.229.231; 2.AB.229.236; 2.AB.229.237; 2.AB.229.238; 2.AB.229.239; 2.AB.229.154; 2.AB.229.157; 2.AB.229.166; 2.AB.229.169; 2.AB.229.172; 2.AB.229.175; 2.AB.229.240; 2.AB.229.244; 2.AB.230.228; 2.AB.230.229; 2.AB.230.230; 2.AB.230.231; 2.AB.230.236; 2.AB.230.237; 2.AB.230.238; 2.AB.230.239; 2.AB.230.154; 2.AB.230.157; 2.AB.230.166; 2.AB.230.169; 2.AB.230.172; 2.AB.230.175; 2.AB.230.240; 2.AB.230.244; 2.AB.231.228; 2.AB.231.229; 2.AB.231.230; 2.AB.231.231; 2.AB.231.236; 2.AB.231.237; 2.AB.231.238; 2.AB.231.239; 2.AB.231.154; 2.AB.231.157; 2.AB.231.166; 2.AB.231.169; 2.AB.231.172; 2.AB.231.175; 2.AB.231.240; 2.AB.231.244; 2.AB.236.228; 2.AB.236.229; 2.AB.236.230; 2.AB.236.231; 2.AB.236.236; 2.AB.236.237; 2.AB.236.238; 2.AB.236.239; 2.AB.236.154; 2.AB.236.157; 2.AB.236.166; 2.AB.236.169; 2.AB.236.172; 2.AB.236.175; 2.AB.236.240; 2.AB.236.244; 2.AB.237.228; 2.AB.237.229; 2.AB.237.230; 2.AB.237.231; 2.AB.237.236; 2.AB.237.237; 2.AB.237.238; 2.AB.237.239; 2.AB.237154; 2.AB.237.157; 2.AB.237.166; 2.AB.237.169; 2.AB.237.172; 2.AB.237.175; 2.AB.237.240; 2.AB.237.244; 2.AB.238.228; 2.AB.238.229; 2.AB.238.230; 2.AB.238.231; 2.AB.238.236; 2.AB.238.237; 2.AB.238.238; 2.AB.238.239; 2.AB.238.154; 2.AB.238.157; 2.AB.238.166; 2.AB.238.169; 2.AB.238.172; 2.AB.238.175; 2.AB.238.240; 2.AB.238.244; 2.AB.239.228; 2.AB.239.229; 2.AB.239.230; 2.AB.239.231; 2.AB.239.236; 2.AB.239.237; 2.AB.239.238; 2.AB.239.239; 2.AB.239.154; 2.AB.239.157; 2.AB.239.166; 2.AB.239.169; 2.AB.239.172; 2.AB.239.175; 2.AB.239.240; 2.AB.239.244; 2.AB.154.228; 2.AB.154.229; 2.AB.154.230; 2.AB.154.231; 2.AB.154.236; 2.AB.154.237; 2.AB.154.238; 2.AB.154.239; 2.AB.154.154; 2.AB.154.157; 2.AB.154.166; 2.AB.154.169; 2.AB.154.172; 2.AB.154.175; 2.AB.154.240; 2.AB.154.244; 2.AB.157.228; 2.AB.157.229; 2.AB.157.230; 2.AB.157.231; 2.AB.157.236; 2.AB.157.237; 2.AB.157.238; 2.AB.157.239; 2.AB.157.154; 2.AB.157.157; 2.AB.157.166; 2.AB.157.169; 2.AB.157.172; 2.AB.157.175; 2.AB.157.240; 2.AB.157.244; 2.AB.166.228; 2.AB.166.229; 2.AB.166.230; 2.AB.166.231; 2.AB.166.236; 2.AB.166.237; 2.AB.166.238; 2.AB.166.239; 2.AB.166.154; 2.AB.166.157; 2.AB.166.166; 2.AB.166.169; 2.AB.166.172; 2.AB.166.175; 2.AB.166.240; 2.AB.166.244; 2.AB.169.228; 2.AB.169.229; 2.AB.169.230; 2.AB.169.231; 2.AB.169.236; 2.AB.169.237; 2.AB.169.238; 2.AB.169.239; 2.AB.169.154; 2.AB.169.157; 2.AB.169.166; 2.AB.169.169; 2.AB.169.172; 2.AB.169.175; 2.AB.169.240; 2.AB.169.244; 2.AB.172.228; 2.AB.172.229; 2.AB.172.230; 2.AB.172.231; 2.AB.172.236; 2.AB.172.237; 2.AB.172.238; 2.AB.172.239; 2.AB.172.154; 2.AB.172.157; 2.AB.172.166; 2.AB.172.169; 2.AB.172.172; 2.AB.172.175; 2.AB.172.240; 2.AB.172.244; 2.AB.175.228; 2.AB.175.229; 2.AB.175.230; 2.AB.175.231; 2.AB.175.236; 2.AB.175.237; 2.AB.175.238; 2.AB.175.239; 2.AB.175.154; 2.AB.175.157; 2.AB.175.166; 2.AB.175.169; 2.AB.175.172; 2.AB.175.175; 2.AB.175.240; 2.AB.175.244; 2.AB.240.228; 2.AB.240.229; 2.AB.240.230; 2.AB.240.231; 2.AB.240.236; 2.AB.240.237; 2.AB.240.238; 2.AB.240.239; 2.AB.240.154; 2.AB.240.157; 2.AB.240.166; 2.AB.240.169; 2.AB.240.172; 2.AB.240.175; 2.AB.240.240; 2.AB.240.244; 2.AB.244.228; 2.AB.244.229; 2.AB.244.230; 2.AB.244.231; 2.AB.244.236; 2.AB.244.237; 2.AB.244.238; 2.AB.244.239; 2.AB.244.154; 2.AB.244.157; 2.AB.244.166; 2.AB.244.169; 2.AB.244.172; 2.AB.244.175; 2.AB.244.240; 2.AB.244.244;

Prodrugs of 2.BI

2.BI.228.228; 2.BI.228.229; 2.BI.228.230; 2.BI.228.231; 2.BI.228.236; 2.BI.228.237; 2.BI.228.238; 2.BI.228.239; 2.BI.228.154; 2.BI.228.157; 2.BI.228.166; 2.BI.228.169; 2.BI.228.172; 2.BI.228.175; 2.BI.228.240; 2.BI.228.244; 2.BI.229.228; 2.BI.229.229; 2.BI.229.230; 2.BI.229.231; 2.BI.229.236; 2.BI.229.237; 2.BI.229.238; 2.BI.229.239; 2.BI.229.154; 2.BI.229.157; 2.BI.229.166; 2.BI.229.169; 2.BI.229.172; 2.BI.229.175; 2.BI.229.240; 2.BI.229.244; 2.BI.230.228; 2.BI.230.229; 2.BI.230.230; 2.BI.23Q.231; 2.BI.230.236; 2.BI.230.237; 2.BI.230.238; 2.BI.23Q.239; 2.BI.230.154; 2.BI.230.157; 2.BI.230.166; 2.BI.23Q.169; 2.BI.230.172; 2.BI.230.175; 2.BI.230.240; 2.BI.230.244; 2.BI.231.228; 2.BI.231.229; 2.BI.231.230; 2.BI.231.231; 2.BI.231.236; 2.BI.231.237; 2.BI.231.238; 2.BI.231.239; 2.BI.231.154; 2.BI.231.157; 2.BI.231.166; 2.BI.231.169; 2.BI.231.172; 2.BI.231.175; 2.BI.231.240; 2.BI.231.244; 2.BI.236.228; 2.BI.236.229; 2.BI.236.230; 2.BI.236.231; 2.BI.236.236; 2.BI.236.237; 2.BI.236.238; 2.BI.236.239; 2.BI.236.154; 2.BI.236.157; 2.BI.236.166; 2.BI.236.169; 2.BI.236.172; 2.BI.236.175; 2.BI.236.240; 2.BI.236.244; 2.BL237.228; 2.BI.237.229; 2.BI.237.230; 2.BI.237.231; 2.BI.237.236; 2.BI.237.237; 2.BI.237.238; 2.BI.237.239; 2.BI.237.154; 2.BI.237.157; 2.BI.237.166; 2.BI.237.169; 2.BI.237.172; 2.BI.237.175; 2.BI.237.240; 2.BI.237.244; 2.BI.238.228; 2.BI.238.229; 2.BI.238.230; 2.BI.238.231; 2.BI.238.236; 2.BI.238.237; 2.BI.238.238; 2.BI.238.239; 2.BI.238.154; 2.BI.238.157; 2.BI.238.166; 2.BI.238.169; 2.BI.238.172; 2.BI.238.175; 2.BI.238.240; 2.BI.238.244; 2.BI.239.228; 2.BI.239.229; 2.BI.239.230; 2.BI.239.231; 2.BI.239.236; 2.BI.239.237; 2.BI.239.238; 2.BI.239.239; 2.BI.239.154; 2.BI.239.157; 2.BI.239.166; 2.BI.239.169; 2.BI.239.172; 2.BI.239.175; 2.BI.239.240; 2.BL239.244; 2.BI.154.228; 2.BI.154.229; 2.BI.154.230; 2.BI.154.231; 2.BI.154.236; 2.BI.154.237; 2.BI.154.238; 2.BI.154.239; 2.BI.154.154; 2.BI.154.157; 2.BI.154.166; 2.BI.154.169; 2.BI.154.172; 2.BI.154.175; 2.BI.154.240; 2.BI.154.244; 2.BI.157.228; 2.BI.157.229; 2.BI.157.230; 2.BI.157.231; 2.BI.157.236; 2.BI.157.237; 2.BI.157.238; 2.BL157.239; 2.BI.157.154; 2.BI.157.157; 2.BI.157.166; 2.BI.157.169; 2.BL157.172; 2.BI.157.175; 2.BI.157.240; 2.BI.157.244; 2.BI.166.228; 2.BI.166.229; 2.BI.166.230; 2.BI.166.231; 2.BI.166.236; 2.BI.166.237; 2.BI.166.238; 2.BI.166.239; 2.BI.166.154; 2.BI.166.157; 2.BI.166.166; 2.BI.166.169; 2.BI.166.172; 2.BI.166.175; 2.BI.166.240; 2.BI.166.244; 2.BI.169.228; 2.BI.169.229; 2.BI.169.230; 2.BI.169.231; 2.BI.169.236; 2.BI.169.237; 2.BI.169.238; 2.BI.169.239; 2.BI.169.154; 2.BI.169.157; 2.BI.169.166; 2.BI.169.169; 2.BI.169.172; 2.BI.169.175; 2.BI.169.240; 2.BI.169.244; 2.BI.172.228; 2.BI.172.229; 2.BI.172.230; 2.BI.172.231; 2.BI.172.236; 2.BI.172.237; 2.BI.172.238; 2.BI.172.239; 2.BI.172.154; 2.BI.172.157; 2.BI.172.166; 2.BI.172.169; 2.BI.172.172; 2.BI.172.175; 2.BI.172.240; 2.BI.172.244; 2.BI.175.228; 2.BI.175.229; 2.BI.175.230; 2.BI.175.231; 2.BI.175.236; 2.BL175.237; 2.BI.175.238; 2.BI.175.239; 2.BI.175.154; 2.BI.175.157; 2.BI.175.166; 2.BI.175.169; 2.BI.175.172; 2.BI.175.175; 2.BI.175.240; 2.BI.175.244; 2.BI.240.228; 2.BI.24Q.229; 2.BI.240.230; 2.BI.240.231; 2.BI.240.236; 2.BL240.237; 2.BI.240.238; 2.BI.240.239; 2.BI.240.154; 2.BI.240.157; 2.BI.240.166; 2.BI.240.169; 2.BI.240.172; 2.BI.240.175; 2.BI.240.240; 2.BI.240.244; 2.BI.244.228; 2.BL244.229; 2.BI.244.230; 2.BI.244.231; 2.BL244.236; 2.BI.244.237; 2.BL244.238;2.BL244.239; 2.BI.244.154; 2.BI.244.157; 2.BI.244.166; 2.BI.244.169; 2.BI.244.172;2.BI.244.175; 2.BI.244.240;2.BI.244.244;

Prodrugs of2.1

2.1.228.228; 2.1.228.229; 2.1.228.230; 2.1.228.231; 2.1.228.236; 2.1.228.237; 2.1.228.238;2.1.228.239;2.1.228.154;2.1.228.157;2.1.228.166;2.1.228.169;2.1.228.172; 2.1.228.175; 2.1.228.240;2.1.228.244; 2.1.229.228;2.1.229.229; 2.1.229.230; 2.1.229.231; 2.1.229.236; 2.1.229.237; 2.1.229.238; 2.1.229.239; 2.1.229.154; 2.1.229.157; 2.1.229.166; 2.1.229.169;2.1.229.172;2.1.229.175; 2.1.229.240;2.1.229.244;2.1.230.228;2.1.230.229; 2.1.230.230; 2.1.230.231; 2.1.230.236; 2.1.230.237; 2.1.230-238; 2.1.230.239; 2.1.230.154; 2.1.230.157; 2.1.230.166; 2.1.230-169; 2.1.230.172; 2.1.230-175; 2.1.230.240; 2.1.230.244; 2.1.231.228;2.1.231.229;2.1.231.230; 2.1.231.231;2.1.231.236;2.1.231.237;2.1.231.238; 2.1.231.239; 2.1.231.154; 2.1.231.157; 2.1.231.166;2.1.231.169; 2.1.231.172; 2.1.231.175; 2.1.231.240; 2.1.231.244; 2.1.236.228; 2.1.236.229; 2.1.236.230; 2.1.236.231; 2.1.236.236; 2.1.236.237;2.1.236.238;2.1.236.239;2.1.236.154;2.1.236.157;2.1.236.166;2.1.236.169; 2.1.236.172; 2.1.236.175;2.1.236.240; 2.1.236.244;2.1.237.228; 2.1.237.229; 2.1.237.230; 2.1.237.231; 2.1.237.236; 2.1.237.237; 2.1.237.238; 2.1.237.239; 2.1.237.154; 2.1.237.157; 2.1.237.166;2.1.237.169;2.1.237.172;2.1.237.175;2.1.237.240;2.1.237.244;2.1.238.228; 2.1.238.229;2.1.238.230;2.1.238.231;2.1.238.236;2.1.238-237; 2.1.238.238;2.1.238.239; 2.1.238.154; 2.1.238.157; 2.1.238.166; 2.1.238.169; 2.1.238.172; 2.1.238.175; 2.1.238.240; 2.1.238.244;2.1.239.228;2.1.239.229;2.1.239.230;2.1.239.231;2.1.239.236;2.1.239.237; 2.1.239.238; 2.1.239.239;2.1.239.154;2.1.239.157;2.1.239.166; 2.1.239.169;2.1.239.172; 2.1.239.175; 2.1.239.240; 2.1.239.244; 2.1.154.228; 2.1.154.229; 2.1.154.230; 2.1.154.231; 2.1.154.236;2.1.154.237;2.1.154.238;2.1.154.239;2.1.154.154;2.1.154.157;2.1.154.166; 2.1.154.169; 2.1.154.172;2.1.154.175;2.1.154.240;2.1.154.244; 2.1.157.228;2.1.157.229; 2.1.157.230; 2.1.157.231; 2.1.157.236; 2.1.157.237; 2.1.157.238; 2.1.157.239; 2.1.157.154; 2.1.157.157;2.1.157.166;2.1.157.169;2.1.157.172;2.1.157.175;2.1.157.240;2.1.157.244; 2.1.166.228;2.1.166.229;2.1.166.230;2.1.166.231;2.1.166.236; 2.1.166.237;2.1.166.238; 2.1.166.239; 2.1.166.154; 2.1.166.157; 2.1.166.166; 2.1.166.169; 2.1.166.172; 2.1.166.175; 2.1.166.240; 2.1.166.244; 2.1.169.228; 2.1.169.229; 2.1.169.230; 2.1.169.231; 2.1.169.236; 2.1.169.237;2.1.169.238;2.1.169.239; 2.1.169.154; 2.1.169.157;2.1.169.166;2.1.169.169; 2.1.169.172; 2.1.169.175; 2.1.169.240; 2.1.169.244; 2.1.172.228; 2.1.172.229; 2.1.172.230; 2.1.172.231; 2.1.172.236; 2.1.172.237; 2.1.172.238; 2.1.172.239; 2.1.172.154;2.1.172.157; 2.1.172.166; 2.1.172.169;2.1.172.172;2.1.172.175;2.1.172.240; 2.1.172.244;2.1.175.228; 2.1.175.229; 2.1.175.230; 2.1.175.231; 2.1.175.236; 2.1.175.237; 2.1.175.238; 2.1.175.239; 2.1.175.154; 2.1.175.157; 2.1.175.166;2.1.175.169;2.1.175.172; 2.1.175.175; 2.1.175.240; 2.1.175.244;2.1.240.228;2.1.240.229;2.1.240.230;2.1.240.231;2.1.240-236;2.1.240.237; 2.1.240.238; 2.1.240.239;2.1.240.154; 2.1.240.157; 2.1.240.166; 2.1.240.169;2.1.240.172; 2.1.240.175; 2.1.240.240; 2.1.240.244; 2.1.244.228; 2.1.244.229; 2.1.244.230; 2.1.244.231; 2.1.244.236; 2.1.244.237;2.1.244.238;2.1.244.239;2.1.244.154;2.1.244.157;2.1.244.166; 2.1.244.169; 2.1.244.172; 2.1.244.175; 2.1.244.240; 2.1.244.244;

Prodrugs of2.T

2.J.228.228;2.J.228.229; 2.J.228.230;2.J.228.231;2.J.228.236;2.J.228.237; 2.J.228.238; 2.J.228.239; 2J.228.154; 2J.228.157; 2J.228.166; 2J.228.169; 2J.228.172; 2J.228.175; 2.J.228.240;2J.228.244; 2J.229.228; 2J.229.229; 2J.229.230; 2J.229.231; 2.J.229.236; 2.J.229.237; 2J.229.238; 2.J.229.239; 2.J.229.154; 2.J.229.157; 2.J.229.166; 2.J.229.169; 2.J.229.172; 2.J.229.175; 2.J.229.240; 2.J.229.244; 2.J.230.228; 2.J.230.229; 2.J.230.230; 2.J.230.231; 2.J.230.236; 2.J.230.237; 2.J.230.238; 2.J.230.239; 2.J.230.154; 2.J.230.157; 2.J.230.166; 2J.230.169; 2.J.230.172; 2J.230.175; 2.J.230.240; 2.J.23Q.244; 2.J.231.228; 2.J.231.229; 2.J.231.230; 2J.231.231; 2J.231.236; 2J.231.237; 2.J.231.238; 2J.231.239; 2J.231.154; 2J.231.157; 2J.231.166; 2J.231.169; 2J.231.172; 2J.231.175; 2J.231.240; 2J.231.244; 2J.236.228; 2J.236.229; 2J.236.230; 2J.236.231; 2J.236.236; 2J.236.237; 2J.236.238; 2.J.236.239; 2J.236.154; 2J.236.157; 2J.236.166; 2.J.236.169; 2J.236.172; 2J.236.175; 2J.236.240; 2J.236.244; 2J.237.228; 2J.237.229; 2J.237.230; 2J.237.231; 2J.237.236; 2J.237.237; 2J.237.238; 2J.237.239; 2J.237.154; 2 J.237.157; 2J.237.166; 2.J.237.169; 2 J.237.172; 2J.237.175; 2.J.237.240; 2J.237.244; 2J.238.228; 2J.238.229; 2.J.238.230; 2J.238.231; 2J.238.236; 2.J.238.237; 2J.238.238; 2.J.238.239; 2 J.238.154; 2.J.238.157; 2J.238.166; 2 J.238.169; 2.J.238.172; 2J.238.175; 2J.238.240; 2 J.238.244; 2J.239.228; 2J.239.229; 2 J.239.230; 2J.239.231; 2J.239.236; 2J.239.237; 2J.239.238; 2J.239.239; 2J.239.154; 2 J.239.157; 2J.239.166; 2.J.239.169; 2J.239.172; 2J.239.175; 2J.239.240; 2.J.239.244; 2J.154.228; 2J.154.229; 2.J.154.230; 2J.154.231; 2J.154.236; 2J.154.237; 2J.154.238; 2J.154.239; 2J.154.154; 2J.154.157; 2J.154.166; 2J.154.169; 2J.154.172; 2J.154.175; 2J.154.240; 2J.154.244; 2J.157.228; 2J.157.229; 2J.157.230; 2J.157.231; 2 J.157.236; 2J.157.237; 2.J.157.238; 2J.157.239; 2J.157.154; 2J.157.157; 2J.157.166; 2 J.157.169; 2J.157.172; 2.J.157.175; 2J.157.240; 2.J.157.244; 2J.166.228; 2.J.166.229; 2J.166.230; 2J.166.231; 2.J.166.236; 2J.166.237; 2J.166.238; 2J.166.239; 2J.166.154; 2J.166.157; 2J.166.166; 2J.166.169; 2J.166.172; 2 J.166.175; 2 J.166.240; 2.J.166.244; 2J.169.228; 2 J.169.229; 2J.169.230; 2J.169.231; 2J.169.236; 2 J.169.237; 2 J.169.238; 2.J.169.239; 2J.169.154; 2J.169.157; 2 J.169.166; 2J.169.169; 2J.169.172; 2J.169.175; 2J.169.240; 2J.169.244; 2J.172.228; 2J.172.229; 2J.172.230; 2J.172.231; 2J.172.236; 2J.172.237; 2J.172.238; 2J.172.239; 2J.172.154; 2J.172.157; 2J.172.166; 2J.172.169; 2J.172.172; 2J.172.175; 2J.172.240; 2J.172.244; 2J.175.228; 2 J.175.229; 2J.175.230; 2J.175.231; 2 J.175.236; 2J.175.237; 2J.175.238; 2J.175.239; 2J.175.154; 2J.175.157; 2J.175.166; 2J.175.169; 2J.175.172; 2J.175.175; 2J.175.240; 2 J.175.244; 2J.240.228; 2 J.240.229; 2J.240.230; 2J.240.231; 2 J.240.236; 2J.240.237; 2J.240.238; 2J.240.239; 2J.240.154; 2J.240.157; 2 J.240.166; 2J.240.169; 2J.240.172; 2.J.240.175; 2J.240.240; 2J.240.244; 2J.244.228; 2J.244.229; 2J.244.230; 2J.244.231; 2J.244.236; 2J.244.237; 2J.244.238; 2J.244.239; 2.J.244.154; 2J.244.157; 2J.244.166; 2J.244.169; 2J.244.172; 2J.244.175; 2 J.244.240; 2J.244.244;

Prodrugs of 2.L

2.L.228.228; 2.L.228.229; 2.L.228.230; 2.L.228.231; 2.L.228.236; 2.L.228.237; 2.L.228.238; 2.L.228.239; 2.L.228.154; 2.L.228.157; 2.L.228.166; 2.L.228.169; 2.L.228.172; 2.L.228.175; 2.L.228.240; 2.L.228.244; 2.L.229.228; 2.L.229.229; 2.L.229.230; 2.L.229.231; 2.L.229.236; 2.L.229.237; 2.L.229.238; 2.L.229.239; 2.L.229.154; 2.L.229.157; 2.L.229.166; 2.L.229.169; 2.L.229.172; 2.L.229.175; 2.L.229.240; 2.L.229.244; 2.L.230.228; 2.L.230.229; 2.L.230.230; 2.L.230.231; 2.L.230.236; 2.L.230.237; 2.L.230.238; 2.L.230.239; 2.L.230.154; 2.L.230.157; 2.L.230.166; 2.L.230.169; 2.L.230.172; 2.L.230.175; 2.L.230.240; 2.L.230.244; 2.L.231.228; 2.L.231.229; 2.L.231.230; 2.L.231.231; 2.L.231.236; 2.L.231.237; 2.L.231.238; 2.L.231.239; 2.L.231.154; 2.L.231.157; 2.L.231.166; 2.L.231.169; 2.L.231.172; 2.L.231.175; 2.L.231.240; 2.L.231.244; 2.L.236.228; 2.L.236.229; 2.L.236.230; 2.L.236.231; 2.L.236.236; 2.L.236.237; 2.L.236.238; 2.L.236.239; 2.L.236.154; 2.L.236.157; 2.L.236.166; 2.L.236.169; 2.L.236.172; 2.L.236.175; 2.L.236.240; 2.L.236.244; 2.L.237.228; 2.L.237.229; 2.L.237.230; 2.L.237.231; 2.L.237.236; 2.L.237.237; 2.L.237.238; 2X.237.239; 2.L.237.154; 2.L.237.157; 2.L.237.166; 2.L.237.169; 2.L.237.172; 2.L.237.175; 2.L.237.240; 2.L.237.244; 2.L.238.228; 2.L.238.229; 2.L.238.230; 2.L.238.231; 2.L.238.236; 2.L.238.237; 2.L.238.238; 2.L.238.239; 2.L.238.154; 2.L.238.157; 2.L.238.166; 2.L.238.169; 2.L.238.172; 2.L.238.175; 2.L.238.240; 2.L.238.244; 2.L.239.228; 2.L.239.229; 2.L.239.230; 2.L.239.231; 2.L.239.236; 2.L.239.237; 2.L.239.238; 2.L.239.239; 2X.239.154; 2.L.239.157; 2.L.239.166; 2.L.239.169; 2.L.239.172; 2.L.239.175; 2.L.239.240; 2.L.239.244; 2X.154.228; 2.L.154.229; 2.L.154.230; 2.L.154.231; 2.L.154.236; 2.L.154.237; 2.L.154.238; 2X.154.239; 2X.154.154; 2X.154.157; 2X.154.166; 2X.154.169; 2X.154.172; 2X.154.175; 2X.154.240; 2X.154.244; 2X.157.228; 2X.157.229; 2X.157.230; 2X.157.231; 2X.157.236; 2X.157.237; 2X.157.238; 2X.157.239; 2X.157.154; 2X.157.157; 2X.157.166; 2X.157.169; 2X.157.172; 2X.157.175; 2X.157.240; 2X.157.244; 2X.166.228; 2X.166.229; 2X.166.230; 2X.166.231; 2X.166.236; 2X.166.237; 2X.166.238; 2X.166.239; 2X.166.154; 2X.166.157; 2X.166.166; 2X.166.169; 2X.166.172; 2X.166.175; 2X.166.240; 2X.166.244; 2X.169.228; 2X.169.229; 2X.169.230; 2.L.169.231; 2X.169.236; 2X.169.237; 2X.169.238; 2X.169.239; 2X.169.154; 2X.169.157; 2X.169.166; 2X.169.169; 2X.169.172; 2X.169.175; 2X.169.240; 2X.169.244; 2X.172.228; 2X.172.229; 2X.172.230; 2X.172.231; 2X.172.236; 2X.172.237; 2X.172.238; 2X.172.239; 2X.172.154; 2X.172.157; 2X.172.166; 2X.172.169; 2X.172.172; 2X.172.175; 2X.172.240; 2X.172.244; 2X.175.228; 2X.175.229; 2X.175.230; 2X.175.231; 2X.175.236; 2X.175.237; 2X.175.238; 2X.175.239; 2X.175.154; 2X.175.157; 2X.175.166; 2X.175.169; 2X.175.172; 2X.175.175; 2X.175.240; 2X.175.244; 2X.240.228; 2X.240.229; 2X.240.230; 2X.240.231; 2X.240.236; 2X.240.237; 2X.240.238; 2X.240.239; 2X.240.154; 2X.240.157; 2X.240.166; 2X.240.169; 2X.240.172; 2X.240.175; 2X.240.240; 2X.240.244; 2X.244.228; 2X.244.229; 2X.244.230; 2X.244.231; 2X.244.236; 2X.244.237; 2X.244.238; 2X.244.239; 2X.244.154; 2X.244.157; 2X.244.166; 2X.244.169; 2X.244.172; 2X.244.175; 2X.244.240; 2X.244.244;

Prodrugs of 2.O

2.O.228.228; 2.O.228.229; 2.O.228.230; 2.O.228.231; 2.O.228.236; 2.O.228.237; 2.O.228.238; 2.O.228.239; 2.O.228.154; 2.O.228.157; 2.O.228.166; 2.O.228.169; 2.O.228.172; 2.O.228.175; 2.O.228.240; 2.O.228.244; 2.O.229.228; 2.O.229.229; 2.O.229.230; 2.O.229.231; 2.O.229.236; 2.O.229.237; 2.O.229.238; 2.O.229.239; 2.O.229.154; 2.O.229.157; 2.O.229.166; 2.O.229.169; 2.O.229.172; 2.O.229.175; 2.O.229.240; 2.O.229.244; 2.O.230.228; 2.O.230.229; 2.O.230-230; 2.O.230.231; 2.O.230.236; 2.O.230.237; 2.O.23Q.238; 2.O.230.239; 2.O.230.154; 2.O.230.157; 2.O.230.166; 2.O.230.169; 2.O.230.172; 2.O.230.175; 2.O.230.240; 2.O.230.244; 2.O.231.228; 2.O.231.229; 2.O.231.230; 2.O.231.231; 2.O.231.236; 2.O.231.237; 2.O.231.238; 2.O.231.239; 2.O.231.154; 2.O.231.157; 2.O.231.166; 2.O.231.169; 2.O.231.172; 2.O.231.175; 2.O.231.240; 2.O.231.244; 2.O.236.228; 2.O.236.229; 2.O.236.230; 2.O.236.231; 2.O.236.236; 2.O.236.237; 2.O.236.238; 2.O.236.239; 2.O.236.154; 2.O.236.157; 2.O.236.166; 2.O.236.169; 2.O.236.172; 2.O.236.175; 2.O.236.240; 2.O.236.244; 2.O.237.228; 2.O.237.229; 2.O.237.230; 2.O.237.231; 2.O.237.236; 2.O.237.237; 2.O.237.238; 2.O.237.239; 2.O.237.154; 2.O.237.157; 2.O.237.166; 2.O.237.169; 2.O.237.172; 2.O.237.175; 2.O.237.240; 2.O.237.244; 2.O.238.228; 2.O.238.229; 2.O.238.230; 2.O.238.231; 2.O.238.236; 2.O.238.237; 2.O.238.238; 2.O.238.239; 2.O.238.154; 2.O.238.157; 2.O.238.166; 2.O.238.169; 2.O.238.172; 2.O.238.175; 2.O.238.240; 2.O.238.244; 2.O.239.228; 2.O.239.229; 2.O.239.230; 2.O.239.231; 2.O.239.236; 2.O.239.237; 2.O.239.238; 2.O.239.239; 2.O.239.154; 2.O.239.157; 2.O.239.166; 2.O.239.169; 2.O.239.172; 2.O.239.175; 2.O.239.240; 2.O.239.244; 2.O.154.228; 2.O.154.229; 2.O.154.230; 2.O.154.231; 2.O.154.236; 2.O.154.237; 2.O.154.238; 2.O.154.239; 2.O.154.154; 2.O.154.157; 2.O.154.166; 2.O.154.169; 2.O.154.172; 2.0-154.175; 2.O.154.240; 2.O.154.244; 2.O.157.228; 2.O.157.229; 2.O.157.230; 2.O.157.231; 2.O.157.236; 2.O.157.237; 2.O.157.238; 2.O.157.239; 2.O.157.154; 2.O.157.157; 2.0.157.166; 2.O.157.169; 2.O.157.172; 2.O.157.175; 2.O.157.240; 2.O.157.244; 2.O.166.228; 2.O.166.229; 2.O.166.230; 2.0-166.231; 2.O.166.236; 2.O.166.237; 2.O.166.238; 2.O.166.239; 2.O.166.154; 2.O.166.157; 2.O.166.166; 2.O.166.169; 2.O.166.172; 2.O.166.175; 2.O.166.240; 2.O.166.244; 2.O.169.228; 2.O.169.229; 2.O.169.230; 2.O.169.231; 2.O.169.236; 2.O.169.237; 2.O.169.238; 2.O.169.239; 2.O.169.154; 2.O.169.157; 2.O.169.166; 2.O.169.169; 2.O.169.172; 2.O.169.175; 2.O.169.240; 2.O.169.244; 2.O.172.228; 2.O.172.229; 2.O.172.230; 2.O.172.231; 2.O.172.236; 2.O.172.237; 2.O.172.238; 2.O.172.239; 2.O.172.154; 2.O.172.157; 2.O.172.166; 2.O.172.169; 2.O.172.172; 2.O.172.175; 2.O.172.240; 2.O.172.244; 2.O.175.228; 2.O.175.229; 2.O.175.230; 2.O.175.231; 2.O.175.236; 2.O.175.237; 2.O.175.238; 2.O.175.239; 2.O.175.154; 2.O.175.157; 2.O.175.166; 2.O.175.169; 2.O.175.172; 2.O.175.175; 2.O.175.240; 2.O.175.244; 2.O.240.228; 2.O.240.229; 2.O.240.230; 2.O.240.231; 2.O.240.236; 2.O.24Q.237; 2.O.240.238; 2.O.240.239; 2.O.240.154; 2.O.240.157; 2.O.240.166; 2.O.240.169; 2.O.240-172; 2.O.240.175; 2.O.240.240; 2.O.240.244; 2.O.244.228; 2.O.244.229; 2.O.244.230; 2.O.244.231; 2.O.244.236; 2.O.244.237; 2.O.244.238; 2.O.244.239; 2.O.244.154; 2.O.244.157; 2.O.244.166; 2.O.244.169; 2.O.244.172; 2.O.244.175; 2.O.244.240; 2.O.244.244;

Prodrugs of 2.P

2.P.228.228; 2.P.228.229; 2.P.228.230; 2.P.228.231; 2.P.228.236; 2.P.228.237; 2.P.228.238; 2.P.228.239; 2.P.228.154; 2.P.228.157; 2.P.228.166; 2.P.228.169; 2.P.228.172; 2.P.228.175; 2.P.228.240; 2.P.228.244; 2.P.229.228; 2.P.229.229; 2.P.229.230; 2.P.229.231; 2.P.229.236; 2.P.229.237; 2.P.229.238; 2.P.229.239; 2.P.229.154; 2.P.229.157; 2.P.229.166; 2.P.229.169; 2.P.229.172; 2.P.229.175; 2.P.229.240; 2.P.229.244; 2.P.230.228; 2.P.230.229; 2.P.230.230; 2.P.230.231; 2.P.230.236; 2.P.230.237; 2.P.230.238; 2.P.230.239; 2.P.230.154; 2.P.230.157; 2.P.230.166; 2.P.230.169; 2.P.230.172; 2.P.230.175; 2.P.230.240; 2.P.230.244; 2.P.231.228; 2.P.231.229; 2.P.231.230; 2.P.231.231; 2.P.231.236; 2.P.231.237; 2.P.231.238; 2.P.231.239; 2.P.231.154; 2.P.231.157; 2.P.231.166; 2.P.231.169; 2.P.231.172; 2.P.231.175; 2.P.231.240; 2.P.231.244; 2.P.236.228; 2.P.236.229; 2.P.236.230; 2.P.236.231; 2.P.236.236; 2.P.236.237; 2.P.236.238; 2.P.236.239; 2.P.236.154; 2.P.236.157; 2.P.236.166; 2.P.236.169; 2.P.236.172; 2.P.236.175; 2.P.236.240; 2.P.236.244; 2.P.237.228; 2.P.237.229; 2.P.237.230; 2.P.237.231; 2.P.237.236; 2.P.237.237; 2.P.237.238; 2.P.237.239; 2.P.237.154; 2.P.237.157; 2.P.237.166; 2.P.237.169; 2.P.237.172; 2.P.237.175; 2.P.237.240; 2.P.237.244; 2.P.238.228; 2.P.238.229; 2.P.238.230; 2.P.238.231; 2.P.238.236; 2.P.238.237; 2.P.238.238; 2.P.238.239; 2.P.238.154; 2.P.238.157; 2.P.238.166; 2.P.238.169; 2.P.238.172; 2.P.238.175; 2.P.238.240; 2.P.238.244; 2.P.239.228; 2.P.239.229; 2.P.239.230; 2.P.239.231; 2.P.239.236; 2.P.239.237; 2.P.239.238; 2.P.239.239; 2.P.239.154; 2.P.239.157; 2.P.239.166; 2.P.239.169; 2.P.239.172; 2.P.239.175; 2.P.239.240; 2.P.239.244; 2.P.154.228; 2.P.154.229; 2.P.154.230; 2.P.154.231; 2.P.154.236; 2.P.154.237; 2.P.154.238; 2.P.154.239; 2.P.154.154; 2.P.154.157; 2.P.154.166; 2.P.154.169; 2.P.154.172; 2.P.154.175; 2.P.154.240; 2.P.154.244; 2.P.157.228; 2.P.157.229; 2.P.157.230; 2.P.157.231; 2.P.157.236; 2.P.157.237; 2.P.157.238; 2.P.157.239; 2.P.157.154; 2.P.157.157; 2.P.157.166; 2.P.157.169; 2.P.157.172; 2.P.157.175; 2.P.157.240; 2.P.157.244; 2.P.166.228; 2.P.166.229; 2.P.166.230; 2.P.166.231; 2.P.166.236; 2.P.166.237; 2.P.166.238; 2.P.166.239; 2.P.166.154; 2.P.166.157; 2.P.166.166; 2.P.166.169; 2.P.166.172; 2.P.166.175; 2.P.166.240; 2.P.166.244; 2.P.169.228; 2.P.169.229; 2.P.169.230; 2.P.169.231; 2.P.169.236; 2.P.169.237; 2.P.169.238; 2.P.169.239; 2.P.169.154; 2.P.169.157; 2.P.169.166; 2.P.169.169; 2.P.169.172; 2.P.169.175; 2.P.169.240; 2.P.169.244; 2.P.172.228; 2.P.172.229; 2.P.172.230; 2.P.172.231; 2.P.172.236; 2.P.172.237; 2.P.172.238; 2.P.172.239; 2.P.172.154; 2.P.172.157; 2.P.172.166; 2.P.172.169; 2.P.172.172; 2.P.172.175; 2.P.172.240; 2.P.172.244; 2.P.175.228; 2.P.175.229; 2.P.175.230; 2.P.175.231; 2.P.175.236; 2.P.175.237; 2.P.175.238; 2.P.175.239; 2.P.175.154; 2.P.175.157; 2.P.175.166; 2.P.175.169; 2.P.175.172; 2.P.175.175; 2.P.175.240; 2.P.175.244; 2.P.240.228; 2.P.240.229; 2.P.240.230; 2.P.240.231; 2.P.240.236; 2.P.240.237; 2.P.240.238; 2.P.240.239; 2.P.240.154; 2.P.240.157; 2.P.240.166; 2.P.240.169; 2.P.24Q.172; 2.P.240.175; 2.P.240.240; 2.P.24Q.244; 2.P.244.228; 2.P.244.229; 2.P.244.230; 2.P.244.231; 2.P.244.236; 2.P.244.237; 2.P.244.238; 2.P.244.239; 2.P.244.154; 2.P.244.157; 2.P.244.166; 2.P.244.169; 2.P.244.172; 2.P.244.175; 2.P.244.240; 2.P.244.244;

Prodrugs of 2.U

2.U.228.228; 2.U.228.229; 2.U.228.230; 2.U.228.231; 2.U.228.236; 2.U.228.237; 2.U.228.238; 2.U.228.239; 2.U.228.154; 2.U.228.157; 2.U.228.166; 2.U.228.169; 2.U.228.172; 2.U.228.175; 2.U.228.240; 2.U.228.244; 2.U.229.228; 2.U.229.229; 2.U.229.230; 2.U.229.231; 2.U.229.236; 2.U.229.237; 2.U.229.238; 2.U.229.239; 2.U.229.154; 2.U.229.157; 2.U.229.166; 2.U.229.169; 2.U.229.172; 2.U.229.175; 2.U.229.240; 2.U.229.244; 2.U.230.228; 2.U.230.229; 2.U.230.230; 2.U.230.231; 2.U.230.236; 2.U.230.237; 2.U.230.238; 2.U.230.239; 2.U.230.154; 2.U.230.157; 2.U.230.166; 2.U.230.169; 2.U.230.172; 2.U.230.175; 2.U.230.240; 2.U.230.244; 2.U.231.228; 2.U.231.229; 2.U.231.230; 2.U.231.231; 2.U.231.236; 2.U.231.237; 2.U.231.238; 2.U.231.239; 2.U.231.154; 2.U.231.157; 2.U.231.166; 2.U.231.169; 2.U.231.172; 2.U.231.175; 2.U.231.240; 2.U.231.244; 2.U.236.228; 2.U.236.229; 2.U.236.230; 2.U.236.231; 2.U.236.236; 2.U.236.237; 2.U.236.238; 2.U.236.239; 2.U.236.154; 2.U.236.157; 2.U.236.166; 2.U.236.169; 2.U.236.172; 2.U.236.175; 2.U.236.240; 2.U.236.244; 2.U.237.228; 2.U.237.229; 2.U.237.230; 2.U.237.231; 2.U.237.236; 2.U.237.237; 2.U-237.238; 2.U.237.239; 2.U.237.154; 2.U.237.157; 2.U.237.166; 2.U.237.169; 2.U.237.172; 2.U.237.175; 2.U.237.240; 2.U-237.244; 2.U.238.228; 2.U.238.229; 2.U.238.230; 2.U.238.231; 2.U.238.236; 2.U.238.237; 2.U.238.238; 2.U.238.239; 2.U.238.154; 2.U.238.157; 2.U.238.166; 2.U.238.169; 2.U.238.172; 2.U.238.175; 2.U.238.240; 2.U.238.244; 2.U.239.228; 2.U.239.229; 2.U.239.230; 2.U.239.231; 2.U.239.236; 2.U.239.237; 2.U.239.238; 2.U.239.239; 2.U.239.154; 2.U.239.157; 2.U.239.166; 2.U.239.169; 2.U.239.172; 2.U.239.175; 2.U.239.240; 2.U.239.244; 2.U.154.228; 2.U.154.229; 2.U.154.230; 2.U.154.231; 2.U.154.236; 2.U.154.237; 2.U.154.238; 2.U.154.239; 2.U.154.154; 2.U.154.157; 2.U.154.166; 2.U.154.169; 2.U.154.172; 2.U.154.175; 2.U.154.240; 2.U.154.244; 2.U.157.228; 2.U.157.229; 2.U.157.230; 2.U.157.231; 2.U.157.236; 2.U.157.237; 2.U.157.238; 2.U.157.239; 2.U.157.154; 2.U.157.157; 2.U.157.166; 2.U.157.169; 2.U.157.172; 2.U.157.175; 2.U.157.240; 2.U.157.244; 2.U.166.228; 2.U.166.229; 2.U.166.230; 2.U.166.231; 2.U.166.236; 2.U.166.237; 2.U.166.238; 2.U.166.239; 2.U.166.154; 2.U.166.157; 2.U.166.166; 2.U.166.169; 2.U.166.172; 2.U.166.175; 2.U.166.240; 2.U.166.244; 2.U.169.228; 2.U.169.229; 2.U.169.230; 2.U.169.231; 2.U.169.236; 2.U.169.237; 2.U.169.238; 2.U.169.239; 2.U.169.154; 2.U.169.157; 2.U.169.166; 2.U.169.169; 2.U.169.172; 2.U.169.175; 2.U.169.240; 2.U.169.244; 2.U.172.228; 2.U.172.229; 2.U.172.230; 2.U.172.231; 2.U.172.236; 2.U.172.237; 2.U.172.238; 2.U.172.239; 2.U.172.154; 2.U.172.157; 2.U.172.166; 2.U.172.169; 2.U.172.172; 2.U.172.175; 2.U.172.240; 2.U.172.244; 2.U.175.228; 2.U.175.229; 2.U.175.230; 2.U.175.231; 2.U.175.236; 2.U.175.237; 2.U.175.238; 2.U.175.239; 2.U.175.154; 2.U.175.157; 2.U.175.166; 2.U.175.169; 2.U.175.172; 2.U.175.175; 2.U.175.240; 2.U.175.244; 2.U.240.228; 2.U.24Q.229; 2.U.240.230; 2.U.240.231; 2.U.240.236; 2.U.240.237; 2.U.240.238; 2.U.240.239; 2.U.240.154; 2.U.240.157; 2.U.240.166; 2.U.240.169; 2.U.240.172; 2.U.240.175; 2.U.240.240; 2.U.240.244; 2.U.244.228; 2.U.244.229; 2.U.244.230; 2.U.244.231; 2.U.244.236; 2.U.244.237; 2.U.244.238; 2.U.244.239; 2.U.244.154; 2.U.244.157; 2.U.244.166; 2.U.244.169; 2.U.244.172; 2.U.244.175; 2.U.244.24Q; 2.U.244.244;

Prodrugs of 2.CD

2.CD.228.228; 2.CD.228.229; 2.CD.228.230; 2.CD.228.231; 2.CD.228.236; 2.CD.228.237; 2.CD.228.238; 2.CD.228.239; 2.CD.228.154; 2.CD.228.157; 2.CD.228.166; 2.CD.228.169; 2.CD.228.172; 2.CD.228.175; 2.CD.228.240; 2.CD.228.244; 2.CD.229.228; 2.CD.229.229; 2.CD.229.230; 2.CD.229.231; 2.CD.229.236; 2.CD.229.237; 2.CD.229.238; 2.CD.229.239; 2.CD.229.154; 2.CD.229.157; 2.CD.229.166; 2.CD.229.169; 2.CD.229.172; 2.CD.229.175; 2.CD.229.240; 2.CD.229.244; 2.CD.230.228; 2.CD.230.229; 2.CD.230.230; 2.CD.230.231; 2.CD.230.236; 2.CD.230.237; 2.CD.230.238; 2.CD.230.239; 2.CD.230.154; 2.CD.230.157; 2.CD.230.166; 2.CD.230.169; 2.CD.230.172; 2.CD.230.175; 2.CD.230.240; 2.CD.230.244; 2.CD.231.228; 2.CD.231.229; 2.CD.231.230; 2.CD.231.231; 2.CD.231.236; 2.CD.231.237; 2.CD.231.238; 2.CD.231.239; 2.CD.231.154; 2.CD.231.157; 2.CD.231.166; 2.CD.231.169; 2.CD.231.172; 2.CD.231.175; 2.CD.231.240; 2.CD.231.244; 2.CD.236.228; 2.CD.236.229; 2.CD.236.230; 2.CD.236.231; 2.CD.236.236; 2.CD.236.237; 2.CD.236.238; 2.CD.236.239; 2.CD.236.154; 2.CD.236.157; 2.CD.236.166; 2.CD.236.169; 2.CD.236.172; 2.CD.236.175; 2.CD.236.240; 2.CD.236.244; 2.CD.237.228; 2.CD.237.229; 2.CD.237.230; 2.CD.237.231; 2.CD.237.236; 2.CD.237.237; 2.CD.237.238; 2.CD.237.239; 2.CD.237.154; 2.CD.237.157; 2.CD.237.166; 2.CD.237.169; 2.CD.237.172; 2.CP.237.175; 2.CD.237.240; 2.CD.237.244; 2.CD.238.228; 2.CD.238.229; 2.CD.238.230; 2.CD.238.231; 2.CD.238.236; 2.CD.238.237; 2.CD.238.238; 2.CD.238.239; 2.CD.238.154; 2.CD.238.157; 2.CD.238.166; 2.CD.238.169; 2.CD.238.172; 2.CD.238.175; 2.CD.238.240; 2.CD.238.244; 2.CD.239.228; 2.CD.239.229; 2.CD.239.230; 2.CD.239.231; 2.CD.239.236; 2.CD.239.237; 2.CD.239.238; 2.CD.239.239; 2.CD.239.154; 2.CD.239.157; 2.CD.239.166; 2.CD.239.169; 2.CD.239.172; 2.CD.239.175; 2.CD.239.240; 2.CD.239.244; 2.CD.154.228; 2.CD.154.229; 2.CD.154.230; 2.CD.154.231; 2.CD.154.236; 2.CD.154.237; 2.CD.154.238; 2.CD.154.239; 2.CD.154.154; 2.CD.154.157; 2.CD.154.166; 2.CD.154.169; 2.CD.154.172; 2.CD.154.175; 2.CD.154.240; 2.CD.154.244; 2.CD.157.228; 2.CD.157.229; 2.CD.157.230; 2.CD.157.231; 2.CD.157.236; 2.CD.157.237; 2.CD.157.238; 2.CD.157.239; 2.CD.157.154; 2.CD.157.157; 2.CD.157.166; 2.CD.157.169; 2.CD.157.172; 2.CD.157.175; 2.CD.157.240; 2.CD.157.244; 2.CD.166.228; 2.CD.166.229; 2.CD.166.230; 2.CD.166.231; 2.CD.166.236; 2.CD.166.237; 2.CD.166.238; 2.CD.166.239; 2.CD.166.154; 2.CD.166.157; 2.CD.166.166; 2.CD.166.169; 2.CD.166.172; 2.CD.166.175; 2.CD.166.240; 2.CD.166.244; 2.CD.169.228; 2.CD.169.229; 2.CD.169.230; 2.CD.169.231; 2.CD.169.236; 2.CD.169.237; 2.CD.169.238; 2.CD.169.239; 2.CD.169.154; 2.CD.169.157; 2.CD.169.166; 2.CD.169.169; 2.CD.169.172; 2.CD.169.175; 2.CD.169.240; 2.CD.169.244; 2.CD.172.228; 2.CD.172.229; 2.CD.172.230; 2.CD.172.231; 2.CD.172.236; 2.CD.172.237; 2.CD.172.238; 2.CD.172.239; 2.CD.172.154; 2.CD.172.157; 2.CD.172.166; 2.CD.172.169; 2.CD.172.172; 2.CD.172.175; 2.CD.172.240; 2.CD.172.244; 2.CD.175.228; 2.CD.175.229; 2.CD.175.230; 2.CD.175.231; 2.CD.175.236; 2.CD.175.237; 2.CD.175.238; 2.CD.175.239; 2.CD.175.154; 2.CD.175.157; 2.CD.175.166; 2.CD.175.169; 2.CD.175.172; 2.CD.175.175; 2.CD.175.240; 2.CD.175.244; 2.CD.240.228; 2.CD.240.229; 2.CD.240.230; 2.CD.240.231; 2.CD.240.236; 2.CD.240.237; 2.CD.240.238; 2.CD.240.239; 2.CD.24Q.154; 2.CD.240.157; 2.CD.240.166; 2.CD.240.169; 2.CD.240.172; 2.CD.240.175; 2.CD.240.240; 2.CD.240.244; 2.CD.244.228; 2.CD.244.229; 2.CD.244.230; 2.CD.244.231; 2.CD.244.236; 2.CD.244.237; 2.CD.244.238; 2.CD.244.239; 2.CD.244.154; 2.CD.244.157; 2.CD.244.166; 2.CD.244.169; 2.CD.244.172; 2.CD.244.175; 2.CD.244.240; 2.CD.244.244;

Prodrugs of 2.EB

2.EB.228.228; 2.EB.228.229; 2.EB.228.230; 2.EB.228.231; 2.EB.228.236; 2.EB.228.237; 2.EB.228.238; 2.EB.228.239; 2.EB.228.154; 2.EB.228.157; 2.EB.228.166; 2.EB.228.169; 2.EB.228.172; 2.EB.228.175; 2.EB.228.240; 2.EB.228.244; 2.EB.229.228; 2.EB.229.229; 2.EB.229.230; 2.EB.229.231; 2.EB.229.236; 2.EB.229.237; 2.EB.229.238; 2.EB.229.239; 2.EB.229.154; 2.EB.229.157; 2.EB.229.166; 2.EB.229.169; 2.EB.229.172; 2.EB.229.175; 2.EB.229.240; 2.EB.229.244; 2.EB.230.228; 2.EB.230.229; 2.EB.230.230; 2.EB.230.231; 2.EB.230.236; 2.EB.230.237; 2.EB.230.238; 2.EB.230.239; 2.EB.230.154; 2.EB.230.157; 2.EB.230.166; 2.EB.230-169; 2.EB.230.172; 2.EB.230.175; 2.EB.230.240; 2.EB.230.244; 2.EB.231.228; 2.EB.231.229; 2.EB.231.230; 2.EB.231.231; 2.EB.231.236; 2.EB.231.237; 2.EB.231.238; 2.EB.231.239; 2.EB.231.154; 2.EB.231.157; 2.EB.231.166; 2.EB.231.169; 2.EB.231.172; 2.EB.231.175; 2.EB.231.240; 2.EB.231.244; 2.EB.236.228; 2.EB.236.229; 2.EB.236.230; 2.EB.236.231; 2.EB.236.236; 2.EB.236.237; 2.EB.236.238; 2.EB.236.239; 2.EB.236.154; 2.EB.236.157; 2.EB.236.166; 2.EB.236.169; 2.EB.236.172; 2.EB.236.175; 2.EB.236.240; 2.EB.236.244; 2.EB.237.228; 2.EB.237.229; 2.EB.237.230; 2.EB.237.231; 2.EB.237.236; 2.EB.237.237; 2.EB.237.238; 2.EB.237.239; 2.EB.237.154; 2.EB.237.157; 2.EB.237.166; 2.EB.237.169; 2.EB.237.172; 2.EB.237.175; 2.EB.237.240; 2.EB.237.244; 2.EB.238.228; 2.EB.238.229; 2.EB.238.230; 2.EB.238.231; 2.EB.238.236; 2.EB.238.237; 2.EB.238.238; 2.EB.238.239; 2.EB.238.154; 2.EB.238.157; 2.EB.238.166; 2.EB.238.169; 2.EB.238.172; 2.EB.238.175; 2.EB.238.24Q; 2.EB.238.244; 2.EB.239.228; 2.EB.239.229; 2.EB.239.230; 2.EB.239.231; 2.EB.239.236; 2.EB.239.237; 2.EB.239.238; 2.EB.239.239; 2.EB.239.154; 2.EB.239.157; 2.EB.239.166; 2.EB.239.169; 2.EB.239.172; 2.EB.239.175; 2.EB.239.240; 2.EB.239.244; 2.EB.154.228; 2.EB.154.229; 2.EB.154.230; 2.EB.154.231; 2.EB.154.236; 2.EB.154.237; 2.EB.154.238; 2.EB.154.239; 2.EB.154.154; 2.EB.154.157; 2.EB.154.166; 2.EB.154.169; 2.EB.154.172; 2.EB.154.175; 2.EB.154.240; 2.EB.154.244; 2.EB.157.228; 2.EB.157.229; 2.EB.157.23Q; 2.EB.157.231; 2.EB.157.236; 2.EB.157.237; 2.EB.157.238; 2.EB.157.239; 2.EB-157.154; 2.EB.157.157; 2.EB.157.166; 2.EB.157.169; 2.EB.157.172; 2. EB.157.175; 2.EB.157.240; 2.EB.157.244; 2.EB.166.228; 2.EB.166.229; 2.EB.166.230; 2.EB.166.231; 2.EB.166.236; 2.EB.166.237; 2.EB.166.238; 2.EB.166.239; 2.EB.166.154; 2.EB.166.157; 2.EB.166.166; 2.EB.166.169; 2.EB.166.172; 2.EB.166.175; 2.EB.166.240; 2.EB.166.244; 2.EB.169.228; 2.EB.169.229; 2.EB.169.230; 2.EB.169.231; 2.EB.169.236; 2.EB.169.237; 2.EB.169.238; 2.EB.169.239; 2.EB.169.154; 2.EB.169.157; 2.EB.169.166; 2.EB.169.169; 2.EB.169.172; 2.EB.169.175; 2.EB.169.240; 2.EB.169.244; 2.EB.172.228; 2.EB.172.229; 2.EB.172.230; 2.EB.172.231; 2.EB.172.236; 2.EB.172.237; 2.EB.172.238; 2.EB.172.239; 2.EB.172.154; 2.EB.172.157; 2.EB.172.166; 2.EB.172.169; 2.EB.172.172; 2.EB.172.175; 2.EB.172.240; 2.EB.172.244; 2.EB.175.228; 2.EB.175.229; 2.EB.175.230; 2.EB.175.231; 2.EB.175.236; 2.EB.175.237; 2.EB.175.238; 2.EB.175.239; 2.EB.175.154; 2.EB.175.157; 2.EB.175.166; 2.EB.175.169; 2.EB.175.172; 2.EB.175.175; 2.EB.175.240; 2.EB.175.244; 2.EB.24Q.228; 2.EB.24Q.229; 2.EB.240.230; 2.EB.240.231; 2.EB.240.236; 2.EB.240.237; 2.EB.240.238; 2.EB.240.239; 2.EB.240.154; 2.EB.240.157; 2.EB.240.166; 2.EB.240.169; 2.EB.24Q.172; 2.EB.240.175; 2.EB.240.240; 2.EB.240.244; 2.EB.244.228; 2.EB.244.229; 2.EB.244.230; 2.EB.244.231; 2.EB.244.236; 2.EB.244.237; 2.EB.244.238; 2.EB.244.239; 2.EB.244.154; 2.EB.244.157; 2.EB.244.166; 2.EB.244.169; 2.EB.244.172; 2.EB.244.175; 2.EB.244.240; 2.EB.244.244;

Prodrugs of 3.B

3.B.228.228; 3.B.228.229; 3.B.228.23Q; 3.B.228.231; 3.B.228.236; 3.B.228.237; 3.B.228.238; 3.B.228.239; 3.B.228.154; 3.B.228.157; 3.B.228.166; 3.B.228.169; 3.B.228.172; 3.B.228.175; 3.B.228.240; 3.B.228.244; 3.B.229.228; 3.B.229.229; 3.B.229.230; 3.B.229.231; 3.B.229.236; 3.B.229.237; 3.B.229.238; 3.B.229.239; 3.B.229.154; 3.B.229.157; 3.B.229.166; 3.B.229.169; 3.B.229.172; 3.B.229.175; 3.B.229.240; 3.B.229.244; 3.B.230.228; 3.B.230.229; 3.B.230.230; 3.B.230.231; 3.B.230.236; 3.B.230.237; 3.B.230.238; 3.B.230.239; 3.B.230.154; 3.B.230.157; 3.B.230.166; 3.B.230.169; 3.B.230.172; 3.B.230.175; 3.B.230.240; 3.B.230.244; 3.B.231.228; 3.B.231.229; 3.B.231.230; 3.B.231.231; 3.B.231.236; 3.B.231.237; 3.B.231.238; 3.B.231.239; 3.B.231.154; 3.B.231.157; 3.B.231.166; 3.B.231.169; 3.B.231.172; 3.B.231.175; 3.B.231.240; 3.B.231.244; 3.B.236.228; 3.B.236.229; 3.B.236.230; 3.B.236.231; 3.B.236.236; 3.B.236.237; 3.B.236.238; 3.B.236.239; 3.B.236.154; 3.B.236.157; 3.B.236.166; 3.B.236.169; 3.B.236.172; 3.B.236.175; 3.B.236.240; 3.B.236.244; 3.B.237.228; 3.B.237.229; 3.B.237.230; 3.B.237.231; 3.B.237.236; 3.B.237.237; 3.B.237.238; 3.B.237.239; 3.B.237.154; 3.B.237.157; 3.B.237.166; 3.B.237.169; 3.B.237.172; 3.B.237.175; 3.B.237.240; 3.B.237.244; 3.B.238.228; 3.B.238.229; 3.B.238.230; 3.B.238.231; 3.B.238.236; 3.B.238.237; 3.B.238.238; 3.B.238.239; 3.B.238.154; 3.B.238.157; 3.B.238.166; 3.B.238.169; 3.B.238.172; 3.B.238.175; 3.B.238.240; 3.B.238.244; 3.B.239.228; 3.B.239.229; 3.B.239.230; 3.B.239.231; 3.B.239.236; 3.B.239.237; 3.B.239.238; 3.B.239.239; 3.B.239.154; 3.B.239.157; 3.B.239.166; 3.B.239.169; 3.B.239.172; 3.B.239.175; 3.B.239.240; 3.B.239.244; 3.B.154.228; 3.B.154.229; 3.B.154.230; 3.B.154.231; 3.B.154.236; 3.B.154.237; 3.B.154.238; 3.B.154.239; 3.B.154.154; 3.B.154.157; 3.B.154.166; 3.B.154.169; 3.B.154.172; 3.B.154.175; 3.B.154.240; 3.B.154.244; 3.B.157.228; 3.B.157.229; 3.B.157.230; 3.B.157.231; 3.B.157.236; 3.B.157.237; 3.B.157.238; 3.B.157.239; 3.B.157.154; 3.B.157.157; 3.B.157.166; 3.B.157.169; 3.B.157.172; 3.B.157.175; 3.B.157.240; 3.B.157.244; 3.B.166.228; 3.B.166.229; 3.B.166.230; 3.B.166.231; 3.B.166.236; 3.B.166.237; 3.B.166.238; 3.B.166.239; 3.B.166.154; 3.B.166.157; 3.B.166.166; 3.B.166.169; 3.B.166.172; 3.B.166.175; 3.B.166.240; 3.B.166.244; 3.B.169.228; 3.B.169.229; 3.B.169.230; 3.B.169.231; 3.B.169.236; 3.B.169.237; 3.B.169.238; 3.B.169.239; 3.B.169.154; 3.B.169.157; 3.B.169.166; 3.B.169.169; 3.B.169.172; 3.B.169.175; 3.B.169.240; 3.B.169.244; 3.B.172.228; 3.B.172.229; 3.B.172.230; 3.B.172.231; 3.B.172.236; 3.B.172.237; 3.B.172.238; 3.B.172.239; 3.B.172.154; 3.B.172.157; 3.B.172.166; 3.B.172.169; 3.B.172.172; 3.B.172.175; 3.B.172.240; 3.B.172.244; 3.B.175.228; 3.B.175.229; 3.B.175.230; 3.B.175.231; 3.B.175.236; 3.B.175.237; 3.B.175.238; 3.B.175.239; 3.B.175.154; 3.B.175.157; 3.B.175.166; 3.B.175.169; 3.B.175.172; 3.B.175.175; 3.B.175.240; 3.B.175.244; 3.B.240.228; 3.B.240.229; 3.B.240.230; 3.B.240.231; 3.B.240.236; 3.B.240.237; 3.B.240.238; 3.B.240.239; 3.B.240.154; 3.B.240.157; 3.B.240.166; 3.B.240.169; 3.B.240.172; 3.B.240.175; 3.B.240.240; 3.B.240.244; 3.B.244.228; 3.B.244.229; 3.B.244.230; 3.B.244.231; 3.B.244.236; 3.B.244.237; 3.B.244.238; 3.B.244.239; 3.B.244.154; 3.B.244.157; 3.B.244.166; 3.B.244.169; 3.B.244.172; 3.B.244.175; 3.B.244.240; 3.B.244.244;

Prodrugs of 3.D

3.D.228.228; 3.D.228.229; 3.D.228.230; 3.D.228.231; 3.D.228.236; 3.D.228.237; 3.D.228.238; 3.D.228.239; 3.D.228.154; 3.D.228.157; 3.D.228.166; 3.D.228.169; 3.D.228.172; 3.D.228.175; 3.D.228.240; 3.D.228.244; 3.D.229.228; 3.D.229.229; 3.D.229.230; 3.D.229.231; 3.D.229.236; 3.D.229.237; 3.D.229.238; 3.D.229.239; 3.D.229.154; 3.D.229.157; 3.D.229.166; 3.D.229.169; 3.D.229.172; 3.D.229.175; 3.D.229.240; 3.D.229.244; 3.D.230.228; 3.D.230.229; 3.D.230.230; 3.D.230.231; 3.D.230.236; 3.D.230.237; 3.D.230.238; 3.D.230.239; 3.D.230.154; 3.D.230.157; 3.D.230.166; 3.D.230.169; 3.D.230.172; 3.D.230.175; 3.D.230.240; 3.D.230.244; 3.D.231.228; 3.D.231.229; 3.D.231.230; 3.D.231.231; 3.D.231.236; 3.D.231.237; 3.D.231.238; 3.D.231.239; 3.D.231.154; 3.D.231.157; 3.D.231.166; 3.D.231.169; 3.D.231.172; 3.D.231.175; 3.D.231.240; 3.D.231.244; 3.D.236.228; 3.D.236.229; 3.D.236.230; 3.D.236.231; 3.D.236.236; 3.D.236.237; 3.D.236.238; 3.D.236.239; 3.D.236.154; 3.D.236.157; 3.D.236.166; 3.D.236.169; 3.D.236.172; 3.D.236.175; 3.D.236.240; 3.D.236.244; 3.D.237.228; 3.D.237.229; 3.D.237.230; 3.D.237.231; 3.D.237.236; 3.D.237.237; 3.D.237.238; 3.D.237.239; 3.D.237.154; 3.D.237.157; 3.D.237.166; 3.D.237.169; 3.D.237.172; 3.D.237.175; 3.D.237.240; 3.D.237.244; 3.D.238.228; 3.D.238.229; 3.D.238.230; 3.D.238.231; 3.D.238.236; 3.D.238.237; 3.D.238.238; 3.D.238.239; 3.D.238.154; 3.D.238.157; 3.D.238.166; 3.D.238.169; 3.D.238.172; 3.D.238.175; 3.D.238.24Q; 3.D.238.244; 3.D.239.228; 3.D.239.229; 3.D.239.230; 3.P.239.231; 3.D.239.236; 3.D.239.237; 3.D.239.238; 3.D.239.239; 3.D.239.154; 3.D.239.157; 3.D.239.166; 3.D.239.169; 3.D.239.172; 3.D.239.175; 3.D.239.240; 3.D.239.244; 3.D.154.228; 3.D.154.229; 3.D.154.230; 3.D.154.231; 3.D.154.236; 3.D.154.237; 3.D.154.238; 3.D.154.239; 3.D.154.154; 3.D.154.157; 3.D.154.166; 3.D.154.169; 3.D.154.172; 3.D.154.175; 3.D.154.240; 3.D.154.244; 3.D.157.228; 3.D.157.229; 3.D.157.230; 3.D.157.231; 3.D.157.236; 3.D.157.237; 3.D.157.238; 3.D.157.239; 3.D.157.154; 3.D.157.157; 3.D.157.166; 3.D.157.169; 3.D.157.172; 3.D.157.175; 3.D.157.240; 3.D.157.244; 3.D.166.228; 3.D.106.229; 3.D.166.230; 3.D.166.231; 3.D.166.236; 3.D.166.237; 3.D.166.238; 3.D.166.239; 3.D.166.154; 3.D.166.157; 3.D.166.166; 3.D.166.169; 3.D.166.172; 3.D.166.175; 3.D.166.240; 3.D.166.244; 3.D.169.228; 3.D.169.229; 3.D.169.230; 3.D.169.231; 3.D.169.236; 3.D.169.237; 3.D.169.238; 3.D.169.239; 3.D.169.154; 3.D.169.157; 3.D.169.166; 3.D.169.169; 3.D.169.172; 3.D.169.175; 3.D.169.240; 3.D.169.244; 3.D.172.228; 3.D.172.229; 3.D.172.230; 3.D.172.231; 3.D.172.236; 3.D.172.237; 3.D.172.238; 3.D.172.239; 3.D.172.154; 3.D.172.157; 3.D.172.166; 3.D.172.169; 3.D.172.172; 3.D.172.175; 3.D.172.240; 3.D.172.244; 3.D.175.228; 3.D.175.229; 3.D.175.230; 3.D.175.231; 3.D.175.236; 3.D.175.237; 3.D.175.238; 3.D.175.239; 3.D.175.154; 3.D.175.157; 3.D.175.166; 3.D.175.169; 3.D.175.172; 3.D.175.175; 3.D.175.240; 3.D.175.244; 3.D.240.228; 3.D.24Q.229; 3.D.240.230; 3.D.240.231; 3.D.240.236; 3.D.240.237; 3.D.240.238; 3.D.240.239; 3.D.240.154; 3.D.240.157; 3.D.240.166; 3.D.240.169; 3.D.240.172; 3.D.240.175; 3.D.240.240; 3.D.240.244; 3.D.244.228; 3.D.244.229; 3.D.244.230; 3.D.244.231; 3.D.244.236; 3.D.244.237; 3.D.244.238; 3.D.244.239; 3.D.244.154; 3.D.244.157; 3.D.244.166; 3.D.244.169; 3.D.244.172; 3.D.244.175; 3.D.244.240; 3.D.244.244;

Prodrugs of 3.AB

3.AB.228.228; 3.AB.228.229; 3.AB.228.230; 3.AB.228.231; 3.AB.228.236; 3 AB.228.237; 3.AB.228.238; 3.AB.228.239; 3.AB.228.154; 3.AB.228.157; 3 AB.228.166; 3.AB.228.169; 3.AB.228.172; 3.AB.228.175; 3.AB.228.240; 3 AB.228.244; 3.AB.229.228; 3.AB.229.229; 3.AB.229.230; 3.AB.229.231; 3 AB.229.236; 3.AB.229.237; 3.AB.229.238; 3.AB.229.239; 3.AB.229.154; 3 AB.229.157; 3.AB.229.166; 3.AB.229.169; 3.AB.229.172; 3.AB.229.175; 3 AB.229.240; 3.AB.229.244; 3.AB.230.228; 3.AB.230.229; 3.AB.230.230; 3.AB.230.231; 3.AB.230.236; 3.AB.230.237; 3.AB.230.238; 3.AB.230.239; 3 AB.230.154; 3.AB.230.157; 3.AB.230.166; 3.AB.23Q.169; 3.AB.230.172; 3.AB.230.175; 3.AB.230.240; 3.AB.23Q.244; 3.AB.231.228; 3.AB.231.229; 3.AB.231.230; 3.AB.231.231; 3.AB.231.236; 3.AB.231.237; 3.AB.231.238; 3.AB.231.239; 3.AB.231.154; 3.AB.231.157; 3.AB.231.166; 3.AB.231.169; 3.AB.231.172; 3.AB.231.175; 3.AB.231.240; 3.AB.231.244; 3.AB.236.228; 3.AB.236.229; 3.AB.236.230; 3.AB.236.231; 3.AB.236.236; 3.AB.236.237; 3.AB.236.238; 3.AB.236.239; 3.AB.236.154; 3-AB.236-157; 3.AB.236.166; 3.AB.236.169; 3.AB.236.172; 3.AB.236.175; 3.AB.236.240; 3.AB.236.244; 3.AB.237.228; 3.AB.237.229; 3.AB.237.230; 3.AB.237.231; 3.AB.237.236; 3.AB.237.237; 3.AB.237.238; 3.AB.237.239; 3.AB.237.154; 3.AB.237.157; 3.AB.237.166; 3.AB.237.169; 3.AB.237.172; 3.AB.237.175; 3.AB.237.240; 3.AB.237.244; 3.AB.238.228; 3.AB.238.229; 3.AB.238.230; 3.AB.238.231; 3.AB.238.236; 3.AB.238.237; 3.AB.238.238; 3.AB.238.239; 3.AB.238.154; 3.AB.238.157; 3.AB.238.166; 3.AB.238.169; 3.AB.238.172; 3.AB.238.175; 3.AB.238.240; 3.AB.238.244; 3.AB.239.228; 3.AB.239.229; 3.AB.239.230; 3.AB.239.231; 3.AB.239.236; 3.AB.239.237; 3.AB.239.238; 3.AB.239.239; 3.AB.239.154; 3.AB.239.157; 3.AB.239.166; 3.AB.239.169; 3.AB.239.172; 3.AB.239.175; 3.AB.239.240; 3.AB.239.244; 3.AB.154.228; 3.AB.154.229; 3.AB.154.230; 3.AB.154.231; 3.AB.154.236; 3.AB.154.237; 3.AB.154.238; 3.AB.154.239; 3.AB.154.154; 3.AB.154.157; 3.AB.154.166; 3.AB.154.169; 3.AB.154.172; 3.AB.154.175; 3.AB.154.240; 3.AB.154.244; 3.AB.157.228; 3.AB.157.229; 3.AB.157.230; 3.AB.157.231; 3.AB.157.236; 3.AB.157.237; 3.AB.157.238; 3.AB.157.239; 3.AB.157.154; 3.AB.157.157; 3.AB.157.166; 3.AB.157.169; 3.AB.157.172; 3.AB.157.175; 3.AB.157.240; 3.AB.157.244; 3.AB.166.228; 3.AB.166.229; 3.AB.166.230; 3.AB.166.231; 3.AB.166.236; 3.AB.166.237; 3.AB.166.238; 3.AB.166.239; 3.AB.166.154; 3.AB.166.157; 3.AB.166.166; 3.AB.166.169; 3.AB.166.172; 3.AB.166.175; 3.AB.166.240; 3.AB.166.244; 3.AB.169.228; 3.AB.169.229; 3.AB.169.230; 3.AB.169.231; 3.AB.169.236; 3.AB.169.237; 3.AB.169.238; 3.AB.169.239; 3.AB.169.154; 3.AB.169.157; 3.AB.169.166; 3.AB.169.169; 3.AB.169.172; 3.AB.169.175; 3.AB.169.240; 3.AB.169.244; 3.AB.172.228; 3.AB.172.229; 3.AB.172.230; 3.AB.172.231; 3.AB.172.236; 3.AB.172.237; 3.AB.172.238; 3.AB.172.239; 3.AB.172.154; 3.AB.172.157; 3.AB.172.166; 3.AB.172.169; 3.AB.172.172; 3.AB.172.175; 3.AB.172.240; 3.AB.172.244; 3.AB.175.228; 3.AB.175.229; 3.AB.175.230; 3.AB.175.231; 3.AB.175.236; 3.AB.175.237; 3.AB.175.238; 3.AB.175.239; 3.AB.175.154; 3.AB.175.157; 3.AB.175.166; 3.AB.175.169; 3.AB.175.172; 3.AB.175.175; 3.AB.175.240; 3.AB.175.244; 3.AB.24Q.228; 3.AB.240.229; 3.AB.240.230; 3.AB.240.231; 3.AB.24Q.236; 3.AB.240.237; 3.AB.240.238; 3.AB.240.239; 3.AB.240.154; 3.AB.24Q.157; 3.AB.240.166; 3.AB.240.169; 3.AB.240.172; 3.AB.240.175; 3.AB.240.24Q; 3.AB.240.244; 3.AB.244.228; 3.AB.244.229; 3.AB.244.230; 3.AB.244.231; 3.AB.244.236; 3.AB.244.237; 3.AB.244.238; 3.AB.244.239; 3.AB.244.154; 3.AB.244.157; 3.AB.244.166; 3.AB.244.169; 3.AB.244.172; 3.AB.244.175; 3.AB.244.240; 3.AB.244.244;

Prodrugs of 3.BI 3.BI.228.228; 3.BI.228.229; 3.BI.228.230; 3.BI.228.231; 3.BI.228.236; 3.BI.228.237; 3.BI.228.238; 3.BI.228.239; 3.BI.228.154; 3.BI.228.157; 3.BI.228.166; 3.BI.228.169; 3.BI.228.172; 3.BI.228.175; 3.BI.228.240; 3.BI.228.244; 3.BI.229.228; 3.BL229.229; 3.BI.229.230; 3.BI.229.231; 3.BI.229.236; 3.BI.229.237; 3.BI.229.238; 3.BI.229.239; 3.BI.229.154; 3.BI.229.157; 3.BI.229.166; 3.BI.229.169; 3.BI.229.172; 3.BI.229.175; 3.BI.229.240; 3.BI.229.244; 3.BI.230.228; 3.BI.230.229; 3.BI.230.230; 3.BI.230.231; 3.BI.230.236; 3.BI.230.237; 3.BI.230.238; 3.BI.230.239; 3.BI.230.154; 3.BI.230.157; 3.BI.230.166; 3.BI.230.169; 3.BI.230.172; 3.BI.230.175; 3.BI.230.240; 3.BI.230.244; 3.BI.231.228; 3.BI.231.229; 3.BI.231.230; 3.BI.231.231; 3.BI.231.236; 3.BI.231.237; 3.BI.231.238; 3.BI.231.239; 3.BI.231.154; 3.BI.231.157; 3.BI.231.166; 3.BI.231.169; 3.BI.231.172; 3.BI.231.175; 3.BI.231.240; 3.BI.231.244; 3.BI.236.228; 3.BI.236.229; 3.BI.236.230; 3.BI.236.231; 3.BI.236.236; 3.BI.236.237; 3.BI.236.238; 3.BI.236.239; 3.BI.236.154; 3.BI.236.157; 3.BI.236.166; 3.BI.236.169; 3.BI.236.172; 3.BI.236.175; 3.BI.236.240; 3.BI.236.244; 3.BI.237.228; 3.BI.237.229; 3.BI.237.230; 3.BI.237.231; 3.BI.237.236; 3.BI.237.237; 3.BI.237.238; 3.BI.237.239; 3.BI.237.154; 3.BI.237.157; 3.BL237.166; 3.BI.237.169; 3.BI.237.172; 3.BI.237.175; 3.BI.237.240; 3.BI.237.244; 3.BI.238.228; 3.BI.238.229; 3.BI.238.230; 3.BI.238.231; 3.BI.238.236; 3.BI.238.237; 3.BI.238.238; 3.BI.238.239; 3.BI.238.154; 3.BI.238.157; 3.BI.238.166; 3.BI.238.169; 3.BI.238.172; 3.BI.238.175; 3.BI.238.240; 3.BI.238.244; 3.BI.239.228; 3.BI.239.229; 3.BI.239.230; 3.BI.239.231; 3.BI.239.236; 3.BI.239.237; 3.BI.239.238; 3.BI.239.239; 3.BI.239.154; 3.BI.239.157; 3.BI.239.166; 3.BI.239.169; 3.BI.239.172; 3.BI.239.175; 3.BI.239.240; 3.BI.239.244; 3.BI.154.228; 3.BI.154.229; 3.BL154.230; 3.BI.154.231; 3.BI.154.236; 3.BI.154.237; 3.BI.154.238; 3.BI.154.239; 3.BI.154.154; 3.BI.154.157; 3.BI.154.166; 3.BI.154.169; 3.BI.154.172; 3.BI.154.175; 3.BI.154.240; 3.BI.154.244; 3.BI.157.228; 3.BI.157.229; 3.BI.157.230; 3.BI.157.231; 331.157236; 331.157.237; 3.BL157.238; 3.BI.157.239; 3.BI.157.154; 3.BI.157.157; 3.BI.157.166; 3.BI.157.169; 3.BI.157.172; 3.BI.157.175; 3.BL157.240; 3.BI.157.244; 3.BI.166.228; 3.BI.166.229; 3.BI.166.230; 3.BI.166.231; 3.BI.166.236; 3.BI.166.237; 3.BI.166.238; 3.BI.166.239; 3.BI.166.154; 3.BI.166.157; 3.BL166.166; 3.BI.166.169; 3.BI.166.172; 3.BI.166.175; 3.BI.166.240; 3.BL166.244; 3.BI.169.228; 3.BI.169.229; 3.BI.169.230; 3.BI.169.231; 3.BI.169.236; 3.BI.169.237; 3.BI.169.238; 3.BI.169.239; 3.BI.169.154; 3.BI.169.157; 3.BI.169.166; 3.BI.169.169; 3.BI.169.172; 3.BI.169.175; 3.BI.169.240; 3.BI.169.244; 3.BI.172.228; 3.BI.172.229; 3.BI.172.230; 3.BI.172.231; 3.BI.172.236; 3.BI.172.237; 3.BI.172.238; 3.BI.172.239; 3.BI.172.154; 3.BI.172.157; 3.BI.172.166; 3.BI.172.169; 3.BI.172.172; 3.BI.172.175; 3.BI.172.240; 3.BI.172.244; 3.BI.175.228; 3.BI.175.229; 3.BI.175.230; 3.BI.175.231; 3.BI.175.236; 3.BI.175.237; 3.BI.175.238; 3.BI.175.239; 3.BI.175.154; 3.BI.175.157; 3.BI.175.166; 3.BI.175.169; 3.BI.175.172; 3.BI.175.175; 3.BI.175.240; 3.BI.175.244; 3.BI.240.228; 3.BI.240.229; 3.BI.240.230; 3.BI.240.231; 3.BI.240.236; 3.BI.240.237; 3.BI.240.238; 3.BI.240.239; 3.BI.240.154; 3.BI.240.157; 3.BI.240.166; 3.BI.240.169; 3.BI.240.172; 3.BI.240.175; 3.BL240.24Q; 3.BI.240.244; 3.BI.244.228; 3.BI.244.229; 3.BI.244.230; 3.BI.244.231; 3.BI.244.236; 3.BI.244.237; 3.BI.244.238; 3.BI.244.239; 3.BI.244.154; 3.BI.244.157; 3.BI.244.166; 3.BI.244.169; 3.BI.244.172; 3.BI.244.175; 3.BI.244.240; 3.BI.244.244;

Prodrugs of 3.1 3.1.228.228; 3.1.228.229; 3.1.228.230; 3.1.228.231; 3.1.228.236; 3.1.228.237; 3.1.228.238; 3.1.228.239; 3.1.228.154; 3.1.228.157; 3.1.228.166; 3.1.228.169; 3.1.228.172; 3.1.228.175; 3.1.228.240; 3.1.228.244; 3.1.229.228; 3.1.229.229; 3.1.229.230; 3.1.229.231; 3.1.229.236; 3.1.229.237; 3.1.229.238; 3.1.229.239; 3.1.229.154; 3.1.229.157; 3.1.229.166; 3.1.229.169; 3.1.229.172; 3.1.229.175; 3.1.229.240; 3.1.229.244; 3.1.230.228; 3.1.230.229; 3.1.230.230; 3.1.230.231; 3.1.230.236; 3.1.230.237; 3.1.230.238; 3.1.230.239; 3.1.230.154; 3.1.230.157; 3.1.230.166; 3.1.230.169; 3.1.230.172; 3.1.230.175; 3.1.230.240; 3.1.230.244; 3.1.231.228; 3.1.231.229; 3.1.231.230; 3.1.231.231; 3.1.231.236; 3.1.231.237; 3.1.231.238; 3.1.231.239; 3.1.231.154; 3.1.231.157; 3.1.231.166; 3.1.231.169; 3.1.231.172; 3.1.231.175; 3.1.231.240; 3.1.231.244; 3.1.236.228; 3.1.236.229; 3.1.236.230; 3.1.236.231; 3.1.236.236; 3.1.236.237; 3.1.236.238; 3.1.236.239; 3.1.236.154; 3.1.236.157; 3.1.236.166; 3.1.236.169; 3.1.236.172; 3.1.236.175; 3.1.236.240; 3.1.236.244; 3.1.237.228; 3.1.237.229; 3.1.237.230; 3.1.237.231; 3.1.237.236; 3.1.237.237; 3.1.237.238; 3.1.237.239; 3.1.237.154; 3.1.237.157; 3.1.237.166; 3.1.237.169; 3.1.237.172; 3.1.237.175; 3.1.237.240; 3.1.237.244; 3.1.238.228; 3.1.238.229; 3.1.238.230; 3.1.238.231; 3.1.238.236; 3.1.238.237; 3.1.238.238; 3.1.238.239; 3.1.238.154; 3.1.238.157; 3.1.238.166; 3.1.238.169; 3.1.238.172; 3.1.238.175; 3.1.238.240; 3.1.238.244; 3.1.239.228; 3.1.239.229; 3.1.239.230; 3.1.239.231; 3.1.239.236; 3.1.239.237; 3.1.239.238; 3.1.239.239; 3.1.239.154; 3-1.239.157; 3.1.239.166; 3.1.239.169; 3.1.239.172; 3.1.239.175; 3.1.239.240; 3.1.239.244; 3.1.154.228; 3.1.154.229; 3.1.154.230; 3.1.154.231; 3.1.154.236; 3.1.154.237; 3.1.154.238; 3.1.154.239; 3.1.154.154; 3.1.154.157; 3.1.154.166; 3.1.154.169; 3.1.154.172; 3.1.154.175; 3.1.154.240; 3.1.154.244; 3.1.157.228; 3.1.157.229; 3.1.157.230; 3.1.157.231; 3.1.157.236; 3.1.157.237; 3.1.157.238; 3.1.157.239; 3.1.157.154; 3.1.157.157; 3.1.157.166; 3.1.157.169; 3.1.157.172; 3.1.157.175; 3.1.157.240; 3.1.157.244; 3.1.166.228; 3.1.166.229; 3.1.166.230; 3.1.166.231; 3.1.166.236; 3.1.166.237; 3.1.166.238; 3.1.166.239; 3.1.166.154; 3.1.166.157; 3.1.166.166; 3.1.166.169; 3.1.166.172; 3.1.166.175; 3.1.166.240; 3.1.166.244; 3.1.169.228; 31169229; 3.1.169.230; 3.1.169.231; 3.1.169.236; 3.1.169.237; 3.1.169.238; 3.1.169.239; 3.1.169.154; 3.1.169.157; 3.1.169.166; 3.1.169.169; 3.1.169.172; 3.1.169.175; 3.1.169.240; 3.1.169.244; 3.1.172.228; 3.1.172.229; 3.1.172.230; 3.1.172.231; 3.1.172.236; 3.1.172.237; 3.1.172.238; 3.1.172.239; 3.1.172.154; 3.1.172.157; 3.1.172.166; 3.1.172.169; 3.1.172.172; 3.1.172.175; 3.1.172.240; 3.1.172.244; 3.1.175.228; 3.1.175.229; 3.1.175.230; 3.1.175.231; 3.1.175.236; 3.1.175.237; 3.1.175.238; 3.1.175.239; 3.1.175.154; 3.1.175.157; 3.1.175.166; 3.1.175.169; 3.1.175.172; 3.1.175.175; 3.1.175.240; 3.1.175.244; 3.1.240.228; 3.1.240.229; 3.1.240.230; 3.1.240.231; 3.1.240.236; 3.1.240.237; 3.1.240.238; 3.1.240.239; 3.1.240.154; 3.1.240.157; 3.1.240.166; 3.1.240.169; 3.1.240.172; 3.1.240.175; 3.1.240.240; 3.1.240.244; 3.1.244.228; 3.1.244.229; 3.1.244.230; 3.1.244.231; 3.1.244.236; 3.1.244.237; 3.1.244.238; 3.1.244.239; 3.1.244.154; 3.1.244.157; 3.1.244.166; 3.1.244.169; 3.1.244.172; 3.1.244.175; 3.1.244.240; 3.1.244.244;

Prodrugs of 3.T

3.J.228.228; 3.J.228.229; 3J.228.230; 3.J.228.231; 3.J.228.236; 3J.228.237; 3J.228.238; 3J.228.239; 3J.228.154; 3 J.228.157; 3 J.228.166; 3J.228.169; 3J.228.172; 3J.228.175; 3J.228.240; 3 J.228.244; 3 J.229.228; 3 J.229.229; 3 J.229.230; 3 J.229.231; 3 J.229.236; 3J.229.237; 3 J.229.238; 3 J.229.239; 3J.229.154; 3 J.229.157; 3 J.229.166; 3 J.229.169; 3 J.229.172; 3J.229.175; 3 J.229.240; 3 J.229.244; 3 J.230.228; 3 J.230.229; 3 J.230.230; 3 J.230.231; 3 J.230.236; 3 J.230.237; 3 J.230.238; 3 J.230.239; 3J.230.154; 3J.230.157; 3J.230.166; 3.J.230.169; 3 J.230.172; 3 J.230.175; 3 J.230.240; 3 J.230.244; 3J.231.228; 3.J.231.229; 3.J.231.230; 3J.231.231; 3.J.231.236; 3.J.231.237; 3J.231.238; 3J.231.239; 3J.231.154; 3J.231.157; 3J.231.166; 3J.231.169; 3.J.231.172; 3J.231.175; 3.J.231.240; 3J.231.244; 3J.236.228; 3J.236.229; 3J.236.230; 3J.236.231; 3 J.236.236; 3 J.236.237; 3 J.236.238; 3 J.236.239; 3 J.236.154; 3 J.236.157; 3 J.236.166; 3J.236.169; 3 J.236.172; 3 J.236.175; 3 J.236.240; 3 J.236.244; 3 J.237.228; 3 J.237.229; 3J.237.230; 3 J.237.231; 3 J.237.236; 3J.237.237; 3 J.237.238; 3 J.237.239; 3 J.237.154; 3 J.237.157; 3J.237.166; 3J.237.169; 3J.237.172; 3J.237.175; 3J.237.240; 3J.237.244; 3J.238.228; 3 J.238.229; 3J.238.230; 3 J.238.231; 3J.238.236; 3J.238.237; 3 J.238.238; 3 J.238.239; 3 J.238.154; 3J.238.157; 3J.238.166; 3J.238.169; 3 J.238.172; 3J.238.175; 3 J.238.240; 3 J.238.244; 3 J.239.228; 3J.239.229; 3.J.239.230; 3 J.239.231; 3 J.239.236; 3.J.239.237; 3 J.239.238; 3 J.239.239; 3 J.239.154; 3J.239.157; 3 J.239.166; 3 J.239.169; 3 J.239.172; 3J.239.175; 3 J.239.240; 3 J.239.244; 3J.154.228; 3J.154.229; 3 J.154.230; 3 J.154.231; 3 J.154.236; 3J.154.237; 3J.154.238; 3 J.154.239; 3 J.154.154; 3 J.154.157; 3 J.154.166; 3 J.154.169; 3J.154.172; 3.J.154.175; 3 J.154.240; 3 J.154.244; 3J.157.228; 3 J.157.229; 3J.157.230; 3.J.157.231; 3 J.157.236; 3 J.157.237; 3J.157.238; 3J.157.239; 3 J.157.154; 3 J.157.157; 3J.157.166; 3 J.157.169; 3 J.157.172; 3.J.157.175; 3 J.157.240; 3 J.157.244; 3J.166.228; 3J.166.229; 3 J.166.230; 3 J.166.231; 3J.166.236; 3J.166.237; 3 J.166.238; 3 J.166.239; 3 J.166.154; 3 J.166.157; 3J.166.166; 3 J.166.169; 3.J.166.172; 3J.166.175; 3 J.166.240; 3J.166.244; 3 J.169.228; 3 J.169.229; 3 J.169.230; 3 J.169.231; 3 J.169.236; 3 J.169.237; 3 J.169.238; 3 J.169.239; 3.J.169.154; 3J.169.157; 3J.169.166; 3.J.169.169; 3 J.169.172; 3J.169.175; 3.J.169.240; 3J.169.244; 3 J.172.228; 3 J.172.229; 3 J.172.230; 3J.172.231; 3J.172.236; 3.J.172.237; 3J.172.238; 3.J.172.239; 3 J.172.154; 3 J.172.157; 3J.172.166; 3J.172.169; 3J.172.172; 3 J.172.175; 3.J.172.240; 3 J.172.244; 3 J.175.228; 3.J.175.229; 3 J.175.230; 3 J.175.231; 3 J.175.236; 3 J.175.237; 3.J.175.238; 3 J.175.239; 3 J.175.154; 3 J.175.157; 3 J.175.166; 3 J.175.169; 3 J.175.172; 3J.175.175; 3.J.175.240; 3 J.175.244; 3 J.240.228; 3 J.240.229; 3J.240.230; 3 J.240.231; 3 J.240.236; 3 J.240.237; 3 J.240.238; 3 J.240.239; 3 J.240.154; 3.J.240.157; 3 J.240.166; 3 J.240.169; 3J.240.172; 3 J.240.175; 3 J.240.240; 3 J.240.244; 3J.244.228; 3 J.244.229; 3 J.244.230; 3 J.244.231; 3J.244.236; 3 J.244.237; 3 J.244.238; 3J.244.239; 3 J.244.154; 3J.244.157; 3 J.244.166; 3 J.244.169; 3 J.244.172; 3 J.244.175; 3.J.244.240; 3 J.244.244;

Prodrugs of 3.L

3.L.228.228; 3.L.228.229; 3.L.228.230; 3.L.228.231; 3.L.228.236; 3.L.228.237; 3.L.228.238; 3.L.228.239; 3.L.228.154; 3.L.228.157; 3.L.228.166; 3.L.228.169; 3.L.228.172; 3.L.228.175; 3.L.228.240; 3.L.228.244; 3.L.229.228; 3.L.229.229; 3.L.229.230; 3.L.229.231; 3.L.229.236; 3.L.229.237; 3.L.229.238; 3.L.229.239; 3.L.229.154; 3.L.229.157; 3.L.229.166; 3.L.229.169; 3.L.229.172; 3.L.229.175; 3.L.229.240; 3.L.229.244; 3.L.230.228; 3.L.230.229; 3.L.230.230; 3.L.230.231; 3.L.230.236; 3.L.230.237; 3.L.230-238; 3.L.230.239; 3.L.230.154; 3.L.230.157; 3.L.230.166; 3.L.230.169; 3.L.230.172; 3.L.230.175; 3.L.230.240; 3.L.230.244; 3.L.231.228; 3.L.231.229; 3.L.231.230; 3.L.231.231; 3.L.231.236; 3.L.231.237; 3.L.231.238; 3.L.231.239; 3.L.231.154; 3.L.231.157; 3.L.231.166; 3.L.231.169; 3.L.231.172; 3.L.231.175; 3.L.231.240; 3.L.231.244; 3.L.236.228; 3.L.236.229; 3.L.236.230; 3.L.236.231; 3.L.236.236; 3.L.236.237; 3.L.236.238; 3.L.236.239; 3.L.236.154; 3.L.236.157; 3.L.236.166; 3.L.236.169; 3.L.236.172; 3.L.236.175; 3.L.236.240; 3.L.236.244; 3.L.237.228; 3.L.237.229; 3.L.237.230; 3.L.237.231; 3.L.237.236; 3.L.237.237; 3.L.237.238; 3.L.237.239; 3.L.237.154; 3.L.237.157; 3.L.237.166; 3.L.237.169; 3.L.237.172; 3.L.237.175; 3.L.237.240; 3.L.237.244; 3.L.238.228; 3.L.238.229; 3.L.238.230; 3.L.238.231; 3.L.238.236; 3.L.238.237; 3.L.238.238; 3.L.238.239; 3.L.238.154; 3.L.238.157; 3.L.238.166; 3.L.238.169; 3.L.238.172; 3.L.238.175; 3.L.238.240; 3X.238.244; 3.L.239.228; 3.L.239.229; 3.L.239.230; 3.L.239.231; 3.L.239.236; 3.L.239.237; 3.L.239.238; 3.L.239.239; 3.L.239.154; 3.L.239.157; 3.L.239.166; 3.L.239.169; 3.L.239.172; 3.L.239.175; 3.L.239.240; 3.L.239.244; 3.L.154.228; 3.L.154.229; 3.L.154.230; 3.L.154.231; 3.L.154.236; 3.L.154.237; 3.L.154.238; 3.L.154.239; 3.L.154.154; 3.L.154.157; 3.L.154.166; 3.L.154.169; 3.L.154.172; 3.L.154.175; 3.L.154.240; 3.L.154.244; 3.L.157.228; 3.L.157.229; 3.L.157.230; 3.L.157.231; 3.L.157.236; 3.L.157.237; 3.L.157.238; 3.L.157.239; 3.L.157.154; 3.L.157.157; 3.L.157.166; 3.L.157.169; 3.L.157.172; 3.L.157.175; 3.L.157.240; 3.L.157.244; 3.L.166.228; 3.L.166.229; 3.L.166.230; 3.L.166.231; 3.L.166.236; 3.L.166.237; 3.L.166.238; 3.L.166.239; 3.L.166.154; 3.L.166.157; 3.L.166.166; 3.L.166.169; 3.L.166.172; 3.L.166.175; 3.L.166.240; 3.L.166.244; 3.L.169.228; 3.L.169.229; 3.L.169.230; 3.L.169.231; 3.L.169.236; 3.L.169.237; 3.L.169.238; 3.L.169.239; 3.L.169.154; 3.L.169.157; 3.L.169.166; 3.L.169.169; 3.L.169.172; 3.L.169.175; 3.L.169.240; 3.L.169.244; 3.L.172.228; 3.L.172.229; 3.L.172.230; 3.L.172.231; 3.L.172.236; 3.L.172.237; 3.L.172.238; 3.L.172.239; 3.L.172.154; 3.L.172.157; 3.L.172.166; 3.L.172.169; 3.L.172.172; 3.L.172.175; 3.L.172.240; 3.L.172.244; 3.L.175.228; 3.L.175.229; 3.L.175.230; 3.L.175.231; 3.L.175.236; 3.L.175.237; 3.L.175.238; 3.L.175.239; 3.L.175.154; 3.L.175.157; 3.L.175.166; 3.L.175.169; 3.L.175.172; 3.L.175.175; 3.L.175.240; 3.L.175.244; 3.L.240.228; 3.L.240.229; 3.L.240.230; 3.L.240.231; 3.L.240.236; 3.L.240.237; 3.L.240.238; 3.L.240.239; 3.L.240.154; 3.L.240.157; 3.L.240.166; 3.L.240.169; 3.L.240.172; 3.L.240.175; 3.L.240.240; 3.L.240.244; 3.L.244.228; 3X.244.229; 3.L.244.230; 3.L.244.231; 3.L.244.236; 3.L.244.237; 3.L.244.238; 3.L.244.239; 3.L.244.154; 3.L.244.157; 3.L.244.166; 3.L.244.169; 3.L.244.172; 3.L.244.175; 3.L.244.240; 3.L.244.244;

Prodrugs of 3.O

3.O.228.228; 3.O.228.229; 3.O.228.23Q; 3.O.228.231; 3.O.228.236; 3.O.228.237; 3.O.228.238; 3.O.228.239; 3.O.228.154; 3.O.228.157; 3.O.228.166; 3.O.228.169; 3.O.228.172; 3.O.228.175; 3.O.228.240; 3.O.228.244; 3.O.229.228; 3.O.229.229; 3.O.229.230; 3.O.229.231; 3.O.229.236; 3.O.229.237; 3.O.229.238; 3.O.229.239; 3.O.229.154; 3.O.229.157; 3.O.229.166; 3.O.229.169; 3.O.229.172; 3.O.229.175; 3.O.229.240; 3.O.229.244; 3.O.230.228; 3.O.230.229; 3.O.230.230; 3.O.230.231; 3.O.230.236; 3.O.230.237; 3.O.230.238; 3.O.230.239; 3.O.230.154; 3.O.230.157; 3.O.230.166; 3.O.230.169; 3.O.23Q.172; 3.O.230.175; 3.O.230.240; 3.O.230.244; 3.O.231.228; 3.O.231.229; 3.O.231.230; 3.O.231.231; 3.O.231.236; 3.O.231.237; 3.O.231.238; 3.O.231.239; 3.O.231.154; 3.O.231.157; 3.O.231.166; 3.O.231.169; 3.O.231.172; 3.O.231.175; 3.O.231.240; 3.O.231.244; 3.O.236.228; 3.O.236.229; 3.O.236.230; 3.O.236.231; 3.O.236.236; 3.O.236.237; 3.O.236.238; 3.O.236.239; 3.O.236.154; 3.O.236.157; 3.O.236.166; 3.O.236.169; 3.O.236.172; 3.O.236.175; 3.O.236.240; 3.O.236.244; 3.O.237.228; 3.O.237.229; 3.O.237.230; 3.O.237.231; 3.O.237.236; 3.O.237.237; 3.O.237.238; 3.O.237.239; 3.O.237.154; 3.O.237.157; 3.O.237.166; 3.O.237.169; 3.O.237.172; 3.O.237.175; 3.O.237.24Q; 3.O.237.244; 3.O.238.228; 3.O.238.229; 3.O.238.230; 3.O.238.231; 3.O.238.236; 3.O.238.237; 3.O.238.238; 3.O.238.239; 3.O.238.154; 3.O.238.157; 3.O.238.166; 3.O.238.169; 3.O.238.172; 3.O.238.175; 3.O.238.240; 3.O.238.244; 3.O.239.228; 3.O.239.229; 3.O.239.230; 3.O.239.231; 3.O.239.236; 3.O.239.237; 3.O.239.238; 3.O.239.239; 3.O.239.154; 3.O.239.157; 3.O.239.166; 3.O.239.169; 3.O.239.172; 3.O.239.175; 3.O.239.240; 3.O.239.244; 3.O.154.228; 3.O.154.229; 3.O.154.230; 3.O.154.231; 3.O.154.236; 3.O.154.237; 3.O.154.238; 3.O.154.239; 3.O.154.154; 3.O.154.157; 3.O.154.166; 3.0.154.169; 3.O.154.172; 3.O.154.175; 3.O.154.240; 3.O.154.244; 3.O.157.228; 3.O.157.229; 3.O.157.230; 3.O.157.231; 3.O.157.236; 3.O.157.237; 3.O.157.238; 3.O.157.239; 3.O.157.154; 3.O.157.157; 3.O.157.166; 3.0.157.169; 3.O.157.172; 3.O.157.175; 3.O.157.240; 3.O.157.244; 3.O.166.228; 3.O.166.229; 3.O.166.230; 3.O.166.231; 3.O.166.236; 3.O.166.237; 3.O.166.238; 3.O.166.239; 3.O.166.154; 3.O.166.157; 3.O.166.166; 3.O.166.169; 3.O.166.172; 3.O.166.175; 3.O.166.240; 3.O.166.244; 3.O.169.228; 3.O.169.229; 3.O.169.230; 3.O.169.231; 3.O.169.236; 3.O.169.237; 3.O.169.238; 3.O.169.239; 3.O.169.154; 3.O.169.157; 3.O.169.166; 3.O.169.169; 3.O.169.172; 3.O.169.175; 3.O.169.240; 3.0.169.244; 3.O.172.228; 3.O.172.229; 3.O.172.230; 3.O.172.231; 3.O.172.236; 3.O.172.237; 3.O.172.238; 3.O.172.239; 3.O.172.154; 3.O.172.157; 3.O.172.166; 3.O.172.169; 3.O.172.172; 3.O.172.175; 3.O.172.240; 3.O.172.244; 3.O.175.228; 3.O.175.229; 3.O.175.230; 3.O.175.231; 3.O.175.236; 3.O.175.237; 3.O.175.238; 3.O.175.239; 3.O.175.154; 3.O.175.157; 3.O.175.166; 3.O.175.169; 3.O.175.172; 3.O.175.175; 3.O.175.240; 3.O.175.244; 3.O.24Q.228; 3.O.240.229; 3.O.240.230; 3.O.240.231; 3.O.240.236; 3.O.240.237; 3.O.240.238; 3.O.240.239; 3.O.240.154; 3.O.240.157; 3.O.240.166; 3.O-240.169; 3.O.240.172; 3.O.240.175; 3.O.24Q.240; 3.O.240.244; 3.O.244.228; 3.O.244.229; 3.O.244.230; 3.O.244.231; 3.O.244.236; 3.O.244.237; 3.O.244.238; 3.O.244.239; 3.O.244.154; 3.O.244.157; 3.O.244.166; 3.O.244.169; 3.O.244.172; 3.O.244.175; 3.O.244.240; 3.O.244.244;

Prodrugs of 3.P

3.P.228.228; 3.P.228.229; 3.P.228.23Q; 3.P.228.231; 3.P.228.236; 3.P.228.237; 3.P.228.238; 3.P.228.239; 3.P.228..154; 3.P.228.157; 3.P.228.166; 3.P.228.169; 3.P.228.172; 3.P.228.175; 3.P.228.240; 3.P.228.244; 3.P.229.228; 3.P.229.229; 3.P.229.230; 3.P.229.231; 3.P.229.236; 3.P.229.237; 3.P.229.238; 3.P.229.239; 3.P.229.154; 3.P.229.157; 3.P.229.166; 3.P.229.169; 3.P.229.172; 3.P.229.175; 3.P.229.240; 3.P.229.244; 3.P.230.228; 3.P.230.229; 3.P.230.230; 3.P.230.231; 3.P.230.236; 3.P.230.237; 3.P.230.238; 3.P.230.239; 3.P.230.154; 3.P.230.157; 3.P.230.166; 3.P.230.169; 3.P.230.172; 3.P.230.175; 3.P.230.240; 3.P.230.244; 3.P.231.228; 3.P.231.229; 3.P.231.230; 3.P.231.231; 3.P.231.236; 3.P.231.237; 3.P.231.238; 3.P.231.239; 3.P.231.154; 3.P.231.157; 3.P.231.166; 3.P.231.169; 3.P.231.172; 3.P.231.175; 3.P.231.240; 3.P.231.244; 3.P.236.228; 3.P.236.229; 3.P.236.230; 3.P.236.231; 3.P.236.236; 3.P.236.237; 3.P.236.238; 3.P.236.239; 3.P.236.154; 3.P.236.157; 3.P.236.166; 3.P.236.169; 3.P.236.172; 3.P.236.175; 3.P.236.240; 3.P.236.244; 3.P.237.228; 3.P.237.229; 3.P.237.230; 3.P.237.231; 3.P.237.236; 3.P.237.237; 3.P.237.238; 3.P.237.239; 3.P.237.154; 3.P.237.157; 3.P.237.166; 3.P.237.169; 3.P.237.172; 3.P.237.175; 3.P.237.240; 3.P.237.244; 3.P.238.228; 3.P.238.229; 3.P.238.230; 3.P.238.231; 3.P.238.236; 3.P.238.237; 3.P.238.238; 3.P.238.239; 3.P.238.154; 3.P.238.157; 3.P.238.166; 3.P.238.169; 3.P.238.172; 3.P.238.175; 3.P.238.240; 3.P.238.244; 3.P.239.228; 3.P.239.229; 3.P.239.230; 3.P.239.231; 3.P.239.236; 3.P.239.237; 3.P.239.238; 3.P.239.239; 3.P.239.154; 3.P.239.157; 3.P.239.166; 3.P.239.169; 3.P.239.172; 3.P.239.175; 3.P.239.240; 3.P.239.244; 3.P.154.228; 3.P.154.229; 3.P.154.230; 3.P.154.231; 3.P.154.236; 3.P.154.237; 3.P.154.238; 3.P.154.239; 3.P.154.154; 3.P.154.157; 3.P.154.166; 3.P.154.169; 3.P.154.172; 3.P.154.175; 3.P.154.240; 3.P.154.244; 3.P.157.228; 3.P.157.229; 3.P.157.230; 3.P.157.231; 3.P.157.236; 3.P.157.237; 3.P.157.238; 3.P.157.239; 3.P.157.154; 3.P.157.157; 3.P.157.166; 3.P.157.169; 3.P.157.172; 3.P.157.175; 3.P.157.240; 3.P.157.244; 3.P.166.228; 3.P.166.229; 3.P.166.230; 3.P.166.231; 3.P.166.236; 3.P.166.237; 3.P.166.238; 3.P.166.239; 3.P.166.154; 3.P.166.157; 3.P.166.166; 3.P.166.169; 3.P.166.172; 3.P.166.175; 3.P.166.240; 3.P.166.244; 3.P.169.228; 3.P.169.229; 3.P.169.230; 3.P.169.231; 3.P.169.236; 3.P.169.237; 3.P.169.238; 3.P.169.239; 3.P.169.154; 3.P.169.157; 3.P.169.166; 3.P.169.169; 3.P.169.172; 3.P.169.175; 3.P.169.240; 3.P.169.244; 3.P.172.228; 3.P.172.229; 3.P.172.230; 3.P.172.231; 3.P.172.236; 3.P.172.237; 3.P.172.238; 3.P.172.239; 3.P.172.154; 3.P.172.157; 3.P.172.166; 3.P.172.169; 3.P.172.172; 3.P.172.175; 3.P.172.240; 3.P.172.244; 3.P.175.228; 3.P.175.229; 3.P.175.230; 3.P.175.231; 3.P.175.236; 3.P.175.237; 3.P.175.238; 3.P.175.239; 3.P.175.154; 3.P.175.157; 3.P.175.166; 3.P.175.169; 3.P.175.172; 3.P.175.175; 3.P.175.240; 3.P.175.244; 3.P.240.228; 3.P.240.229; 3.P.240.230; 3.P.240.231; 3.P.240.236; 3.P.240.237; 3.P.240.238; 3.P.240.239; 3.P.240.154; 3.P.240.157; 3.P.240.166; 3.P.240.169; 3.P.240.172; 3.P.240.175; 3.P.24Q.240; 3.P.240.244; 3.P.244.228; 3.P.244.229; 3.P.244.230; 3.P.244.231; 3.P.244.236; 3.P.244.237; 3.P.244.238; 3.P.244.239; 3.P.244.154; 3.P.244.157; 3.P.244.166; 3.P.244.169; 3.P.244.172; 3.P.244.175; 3.P.244.240; 3.P.244.244;

Prodrugs of 3.U

3.U.228.228; 3.U.228.229; 3.U.228.230; 3.U.228.231; 3.U.228.236; 3.U.228.237; 3.U.228.238; 3.U.228.239; 3.U.228.154; 3.U.228.157; 3.U.228.166; 3.U.228.169; 3.U.228.172; 3.U.228.175; 3.U.228.240; 3.U.228.244; 3.U.229.228; 3.U.229.229; 3.U.229.230; 3.U.229.231; 3.U.229.236; 3.U.229.237; 3.U.229.238; 3-U.229.239; 3.U.229.154; 3.U.229.157; 3.U.229.166; 3.U.229.169; 3.U.229.172; 3.U.229.175; 3.U.229.240; 3.U.229.244; 3.U.230.228; 3.U.230.229; 3.U.230.230; 3.U.230.231; 3.U.230.236; 3.U.230.237; 3.U.230.238; 3.U.230.239; 3.U.230.154; 3.U.230.157; 3.U.230.166; 3.U.230.169; 3.U.230.172; 3.U.230.175; 3.U.230.240; 3.U.230.244; 3.U.231.228; 3.U.231.229; 3.U.231.230; 3.U.231.231; 3.U.231.236; 3.U.231.237; 3.U.231.238; 3.U.231.239; 3.U.231.154; 3.U.231.157; 3.U.231.166; 3.U.231.169; 3.U.231.172; 3.U.231.175; 3.U.231.240; 3.U.231.244; 3.U.236.228; 3.U.236.229; 3.U.236.230; 3.U.236.231; 3.U.236.236; 3.U.236.237; 3.U.236.238; 3.U.236.239; 3.U.236.154; 3.U.236.157; 3.U.236.166; 3.U.236.169; 3.U.236.172; 3.U.236.175; 3.U.236.240; 3.U.236.244; 3.U.237.228; 3.U.237.229; 3.U.237.230; 3.U.237.231; 3.U.237.236; 3.U.237.237; 3.U.237.238; 3.U.237.239; 3.U.237.154; 3.U.237.157; 3.U.237.166; 3.U.237.169; 3.U.237.172; 3.U.237.175; 3.U.237.240; 3.U.237.244; 3.U.238.228; 3.U.238.229; 3.U.238.230; 3.U.238.231; 3.U.238.236; 3.U.238.237; 3.U.238.238; 3.U.238.239; 3.U.238.154; 3.U.238.157; 3.U.238.166; 3.U.238.169; 3.U.238.172; 3.U.238.175; 3.U.238.240; 3.U.238.244; 3.U.239.228; 3.U.239.229; 3.U.239.230; 3.U.239.231; 3.U.239.236; 3.U.239.237; 3.U.239.238; 3.U.239.239; 3.U.239.154; 3.U.239.157; 3.U.239.166; 3.U.239.169; 3.U.239.172; 3.U.239.175; 3.U.239.240; 3.U.239.244; 3.U.154.228; 3.U.154.229; 3.U.154.230; 3.U.154.231; 3.U.154.236; 3.U.154.237; 3.U.154.238; 3.U.154.239; 3.U.154.154; 3.U.154.157; 3.U.154.166; 3.U.154.169; 3.U.154.172; 3.U.154.175; 3.U.154.240; 3.U.154.244; 3.U.157.228; 3.U.157.229; 3.U.157.230; 3.U.157.231; 3.U.157.236; 3.U.157.237; 3.U.157.238; 3.U.157.239; 3.U.157.154; 3.U.157.157; 3.U.157.166; 3.U.157.169; 3.U.157.172; 3.U.157.175; 3.U.157.240; 3.U.157.244; 3.U.166.228; 3.U.166.229; 3.U.166.230; 3.U.166.231; 3.U.166.236; 3.U.166.237; 3.U.166.238; 3.U.166.239; 3.U.166-154; 3.U.166.157; 3.U.166.166; 3.U.166.169; 3.U.166.172; 3.U.166.175; 3.U.166.240; 3.U.166.244; 3.U.169.228; 3.U.169.229; 3.U.169.230; 3.U.169.231; 3.U.169.236; 3.U.169.237; 3.U.169.238; 3.U.169.239; 3.U.169.154; 3.U.169.157; 3.U.169.166; 3.U.169.169; 3.U.169.172; 3.U.169.175; 3.U.169.240; 3.U.169.244; 3.U.172.228; 3.U.172.229; 3.U.172.230; 3.U.172.231; 3.U.172.236; 3.U.172.237; 3.U.172.238; 3.U.172.239; 3.U.172.154; 3.U.172.157; 3.U.172.166; 3.U.172.169; 3.U.172.172; 3.U.172.175; 3.U.172.240; 3.U.172.244; 3.U.175.228; 3.U.175.229; 3.U.175.230; 3.U.175.231; 3.U.175.236; 3.U.175.237; 3.U.175.238; 3.U.175.239; 3.U.175.154; 3.U.175.157; 3.U.175.166; 3.U.175.169; 3.U.175.172; 3.U.175.175; 3.U.175.240; 3.U.175.244; 3.U.240.228; 3.U.240.229; 3.U.240.230; 3.U.240.231; 3.U.240.236; 3.U.240.237; 3.U.240.238; 3.U.240.239; 3.U.240.154; 3.U.240.157; 3.U.240.166; 3.U.240.169; 3.U.240.172; 3.U.240.175; 3.U.240.240; 3.U.240.244; 3.U.244.228; 3.U.244.229; 3.U.244.230; 3.U.244.231; 3.U.244.236; 3.U.244.237; 3.U.244.238; 3.U.244.239; 3.U.244.154; 3.U.244.157; 3.U.244.166; 3.U.244.169; 3.U.244.172; 3.U.244.175; 3.U.244.24Q; 3.U.244.244;

Prodrugs of 3.CD

3.CD.228.228; 3.CD.228.229; 3.CD.228.230; 3.CD.228.231; 3.CD.228.236; 3.CD.228.237; 3.CD.228.238; 3.CD.228.239; 3.CD.228.154; 3.CD.228.157; 3.CD.228.166; 3.CD.228.169; 3.CD.228.172; 3.CD.228.175; 3.CD.228.240; 3.CD.228.244; 3.CD.229.228; 3.CD.229.229; 3.CD.229.230; 3.CD.229.231; 3.CD.229.236; 3.CD.229.237; 3.CD.229.238; 3.CD.229.239; 3.CD.229.154; 3.CD.229.157; 3.CD.229.166; 3.CD.229.169; 3.CD.229.172; 3.CD.229.175; 3.CD.229.240; 3.CD.229.244; 3.CD.230.228; 3.CD.230.229; 3.CD.230.230; 3.CD.230.231; 3.CD.230.236; 3.CD.230.237; 3.CD.230.238; 3.CD.230.239; 3.CD.230.154; 3.CD.230.157; 3.CD.230.166; 3.CD.230.169; 3.CD.230.172; 3.CD.230.175; 3.CD.230.240; 3.CD.230.244; 3.CD.231.228; 3.CD.231.229; 3.CD.231.230; 3.CD.231.231; 3.CD.231.236; 3.CD.231.237; 3.CD.231.238; 3.CD.231.239; 3.CD.231.154; 3.CD.231.157; 3.CD.231.166; 3.CD.231.169; 3.CD.231.172; 3.CD.231.175; 3.CD.231.240; 3.CD.231.244; 3.CD.236.228; 3.CD.236.229; 3.CD.236.230; 3.CD.236.231; 3.CD.236.236; 3.CD.236.237; 3.CD.236.238; 3.CD.236.239; 3.CD.236.154; 3.CD.236.157; 3.CD.236.166; 3.CD.236.169; 3.CD.236.172; 3.CD.236.175; 3.CD.236.240; 3.CD.236.244; 3.CD.237.228; 3.CD.237.229; 3.CD.237.230; 3.CD.237.231; 3.CD.237.236; 3.CD.237.237; 3.CD.237.238; 3.CD.237.239; 3.CD.237.154; 3.CD.237.157; 3.CD.237.166; 3.CD.237.169; 3.CD.237.172; 3.CD.237.175; 3.CD.237.240; 3.CD.237.244; 3.CD.238.228; 3.CD.238.229; 3.CD.238.230; 3.CD.238.231; 3.CD.238.236; 3.CD.238.237; 3.CD.238.238; 3.CD.238.239; 3.CD.238.154; 3.CD.238.157; 3.CD.238.166; 3.CD.238.169; 3.CD.238.172; 3.CD.238.175; 3.CD.238.240; 3.CD.238.244; 3.CD.239.228; 3.CD.239.229; 3.CD.239.230; 3.CD.239.231; 3.CD.239.236; 3.CD.239.237; 3.CD.239.238; 3.CD.239.239; 3.CD.239.154; 3.CD.239.157; 3.CD.239.166; 3.CD.239.169; 3. CD. ,239.172; 3.CD.239.175; 3.CD.239.240; 3.CD.239.244; 3.CD.154.228; 3.CD.154.229; 3.CD.154.230; 3.CD.154.231; 3.CD.154.236; 3.CD.154.237; 3.CD.154.238; 3.CD.154.239; 3.CD.154.154; 3.CD.154.157; 3.CD.154.166; 3.CD.154.169; 3.CD.154.172; 3.CD.154.175; 3.CD.154.240; 3.CD.154.244; 3.CD.157.228; 3.CD.157.229; 3.CD.157.230; 3.CD.157.231; 3.CD.157.236; 3.CD.157.237; 3.CD.157.238; 3.CD.157.239; 3.CD.157.154; 3.CD.157.157; 3.CD.157.166; 3.CD.157.169; 3.CD.157.172; 3.CD.157.175; 3.CD.157.240; 3.CD.157.244; 3.CD.166.228; 3.CD.166.229; 3.CD.166.230; 3.CD.166.231; 3.CD.166.236; 3.CD.166.237; 3.CD.166.238; 3.CD.166.239; 3.CD.166.154; 3.CD.166.157; 3.CD.166.166; 3.CD.166.169; 3. CD.166.172; 3-CD.166.175; 3.CD.166.240; 3.CD.166.244; 3.CD.169.228; 3.CD.169.229; 3.CD.169.230; 3.CD.169.231; 3.CD.169.236; 3.CD.169.237; 3.CD.169.238; 3.CD.169.239; 3.CD.169.154; 3.CD.169.157; 3.CD.169.166; 3.CD.169.169; 3.CD.169.172; 3.CD.169.175; 3.CD.169.240; 3.CD.169.244; 3.CD.172.228; 3.CD.172.229; 3.CD.172.230; 3.CD.172.231; 3. CD.172236; 3. CD.172.237; 3.CD.172.238; 3. CD.172.239; 3.CD.172.154; 3.CD.172.157; 3.CD.172.166; 3.CD.172.169; 3.CD.172.172; 3.CD.172.175; 3.CD.172.240; 3.CD.172.244; 3.CD.175.228; 3.CD.175.229; 3.CD.175.230; 3.CD.175.231; 3.CD.175.236; 3.CD.175.237; 3.CD.175.238; 3.CD.175.239; 3.CD.175.154; 3.CD.175.157; 3.CD.175.166; 3.CD.175.169; 3.CD.175.172; 3.CD.175.175; 3.CD.175.240; 3.CD.175.244; 3.CD.240.228; 3.CD.240.229; 3.CD.240.230; 3.CD.240.231; 3.CD.240.236; 3.CD.240.237; 3.CD.240.238; 3.CD.240.239; 3.CD.240.154; 3.CD.240.157; 3.CD.240.166; 3.CD.240.169; 3.CD.240.172; 3.CD.240.175; 3.CD.240.240; 3.CD.240.244; 3.CD.244.228; 3.CD.244.229; 3.CD.244.230; 3.CD.244.231; 3.CD.244.236; 3.CD.244.237; 3.CD.244.238; 3.CD.244.239; 3.CD.244.154; 3.CD.244.157; 3.CD.244.166; 3.CD.244.169; 3.CD.244.172; 3.CD.244.175; 3.CD.244.240; 3.CD.244.244;

Prodrugs of 3.EB

3.EB.228.228; 3.EB.228.229; 3.EB.228.230; 3.EB.228.231; 3.EB.228.236; 3.EB.228.237; 3.EB.228.238; 3.EB.228.239; 3.EB.228.154; 3.EB.228.157; 3.EB.228.166; 3.EB.228.169; 3.EB.228.172; 3.EB.228.175; 3.EB.228.240; 3.EB.228.244; 3.EB.229.228; 3.EB.229.229; 3.EB.229.230; 3.EB.229.231; 3.EB.229.236; 3.EB.229.237; 3.EB.229.238; 3.EB.229.239; 3.EB.229.154; 3.EB.229.157; 3.EB.229.166; 3.EB.229.169; 3.EB.229.172; 3.EB.229.175; 3.EB.229.240; 3.EB.229.244; 3.EB.230.228; 3.EB.230.229; 3.EB.230.230; 3.EB.230.231; 3.EB.230.236; 3.EB.230.237; 3.EB.230.238; 3.EB.230.239; 3.EB.230.154; 3.EB.230.157; 3.EB.230.166; 3.EB.230.169; 3.EB.230.172; 3.EB.230.175; 3.EB.230.240; 3.EB.230.244; 3.EB.231.228; 3.EB.231.229; 3.EB.231.230; 3.EB.231.231; 3.EB.231.236; 3.EB.231.237; 3.EB.231.238; 3.EB.231.239; 3.EB.231.154; 3.EB.231.157; 3.EB.231.166; 3.EB.231.169; 3.EB.231.172; 3.EB.231.175; 3.EB.231.240; 3.EB.231.244; 3.EB.236.228; 3.EB.236.229; 3.EB.236.230; 3.EB.236.231; 3.EB.236.236; 3.EB.236.237; 3.EB.236.238; 3.EB.236.239; 3.EB.236.154; 3.EB.236.157; 3.EB.236.166; 3.EB.236.169; 3.EB.236.172; 3.EB.236.175; 3.EB.236.240; 3.EB.236.244; 3.EB.237.228; 3.EB.237.229; 3.EB.237.230; 3.EB.237.231; 3.EB.237.236; 3.EB.237.237; 3.EB.237.238; 3.EB.237.239; 3.EB.237.154; 3.EB.237.157; 3.EB.237.166; 3.EB.237.169; 3.EB.237.172; 3.EB.237.175; 3.EB.237.240; 3.EB.237.244; 3.EB.238.228; 3.EB.238.229; 3.EB.238.230; 3.EB.238.231; 3.EB.238.236; 3.EB.238.237; 3.EB.238.238; 3.EB.238.239; 3.EB.238.154; 3.EB.238.157; 3.EB.238.166; 3.EB.238.169; 3.EB.238.172; 3.EB.238.175; 3.EB.238.240; 3.EB.238.244; 3.EB.239.228; 3.EB.239.229; 3.EB.239.230; 3.EB.239.231; 3.EB.239.236; 3.EB.239.237; 3.EB.239.238; 3.EB.239.239; 3.EB.239.154; 3.EB.239.157; 3.EB.239.166; 3.EB.239.169; 3.EB.239.172; 3.EB.239.175; 3.EB.239.240; 3.EB.239.244; 3.EB.154.228; 3.EB.154.229; 3.EB.154.230; 3.EB.154.231; 3.EB.154.236; 3.EB.154.237; 3.EB.154.238; 3.EB.154.239; 3.EB.154.154; 3.EB.154.157; 3.EB.154.166; 3.EB.154.169; 3.EB.154.172; 3.EB.154.175; 3.EB.154.240; 3.EB.154.244; 3.EB.157.228; 3.EB.157.229; 3.EB.157.230; 3.EB.157.231; 3.EB.157.236; 3.EB.157.237; 3.EB.157.238; 3.EB.157.239; 3.EB.157.154; 3.EB.157.157; 3.EB.157.166; 3.EB.157.169; 3.EB.157.172; 3.EB.157.175; 3.EB.157.240; 3.EB.157.244; 3.EB.166.228; 3.EB.166.229; 3.EB.166.230; 3.EB.166.231; 3.EB.166.236; 3.EB.166.237; 3.EB.166.238; 3.EB.166.239; 3.EB.166.154; 3.EB.166.157; 3.EB.166.166; 3.EB.166.169; 3.ΕB.166.172; 3.EB.166.175; 3.EB.166.240; 3.EB.166.244; 3.EB.169.228; 3.EB.169.229; 3.EB.169.230; 3.EB.169.231; 3.EB.169.236; 3.EB.169.237; 3.EB.169.238; 3.EB.169.239; 3.EB.169.154; 3.EB.169.157; 3.EB.169.166; 3.EB.169.169; 3.EB.169.172; 3.EB.169.175; 3.EB.169.240; 3.EB.169.244; 3.EB.172.228; 3.EB.172.229; 3.EB.172.230; 3.EB.172.231; 3.EB.172.236; 3.EB.172.237; 3.EB.172.238; 3.EB.172.239; 3.EB.172.154; 3.EB.172.157; 3.EB.172.166; 3.EB.172.169; 3.EB.172.172; 3.EB.172.175; 3.EB.172.240; 3.EB.172.244; 3.EB.175.228; 3.EB.175.229; 3.EB.175.230; 3.EB.175.231; 3.EB.175.236; 3.EB.175.237; 3.EB.175.238; 3.EB.175.239; 3.EB.175.154; 3.EB.175.157; 3.EB.175.166; 3.EB.175.169; 3. ,EB.175.172; 3.EB.175.175; 3.EB.175.240; 3.EB.175.244; 3.EB.240.228; 3.EB.240.229; 3.EB.240.230; 3.EB.240.231; 3.EB.240.236; 3.EB.240.237; 3.EB.240.238; 3.EB.240.239; 3.EB.240.154; 3.EB.240.157; 3.EB.240.166; 3.EB.240.169; 3.EB.240.172; 3.EB.240.175; 3.EB.240.240; 3.EB.240.244; 3.EB.244.228; 3.EB.244.229; 3.EB.244.230; 3.EB.244.231; 3.EB.244.236; 3.EB.244.237; 3.EB.244.238; 3.EB.244.239; 3.EB.244.154; 3.EB.244.157; 3.EB.244.166; 3.EB.244.169; 3.EB.244.172; 3.EB.244.175; 3.EB.244.240; 3.EB.244.244;

Prodrugs of 4.B

4.B.228.228; 4.B.228.229; 4.B.228.230; 4.B.228.231; 4.B.228.236; 4.B.228.237; 4.B.228.238; 4.B.228.239; 4.B.228.154; 4.B.228.157; 4.B.228.166; 4.B.228.169; 4.B.228.172; 4.B.228.175; 4.B.228.240; 4.B.228.244; 4.B.229.228; 4.B.229.229; 4.B.229.230; 4.B.229.231; 4.B.229.236; 4.B.229.237; 4.B.229.238; 4.B.229.239; 4.B.229.154; 4.B.229.157; 4.B.229.166; 4.B.229.169; 4.B.229.172; 4.B.229.175; 4.B.229.240; 4.B.229.244; 4.B.230.228; 4.B.230.229; 4.B.230.230; 4.B.230.231; 4.B.230.236; 4.B.230.237; 4.B.230.238; 4.B.230.239; 4.B.230.154; 4.B.230.157; 4.B.230.166; 4.B.230.169; 4.B.230.172; 4.B.230.175; 4.B.230.240; 4.B.230.244; 4.B.231.228; 4.B.231.229; 4.B.231.23Q; 4.B.231.231; 4.B.231.236; 4.B.231.237; 4.B.231.238; 4.B.231.239; 4.B.231.154; 4.B.231.157; 4.B.231.166; 4.B.231.169; 4.B.231.172; 4.B.231.175; 4.B.231.240; 4.B.231.244; 4.B.236.228; 4.B.236.229; 4.B.236.230; 4.B.236.231; 4.B.236.236; 4.B.236.237; 4.B.236.238; 4.B.236.239; 4.B.236.154; 4.B.236.157; 4.B.236.166; 4.B.236.169; 4.B.236.172; 4.B.236.175; 4.B.236.240; 4.B.236.244; 4.B.237.228; 4.B.237.229; 4.B.237.23Q; 4.B.237.231; 4.B.237.236; 4.B.237.237; 4.B.237.238; 4.B.237.239; 4.B.237.154; 4.B.237.157; 4.B.237.166; 4.B.237.169; 4.B.237.172; 4.B.237.175; 4.B.237.240; 4.B.237.244; 4.B.238.228; 4.B.238.229; 4.B.238.230; 4.B.238.231; 4.B.238.236; 4.B.238.237; 4.B.238.238; 4.B.238.239; 4.B.238.154; 4.B.238.157; 4.B.238.166; 4.B.238.169; 4.B.238.172; 4.B.238.175; 4.B.238.24Q; 4.B.238.244; 4.B.239.228; 4.B.239.229; 4.B.239.230; 4.B.239.231; 4.B.239.236; 4.B.239.237; 4.B.239.238; 4.B.239.239; 4.B.239.154; 4.B.239.157; 4.B.239.166; 4.B.239.169; 4.B.239.172; 4.B.239.175; 4.B.239.240; 4.B.239.244; 4.B.154.228; 4.B.154.229; 4.B.154.230; 4.B.154.231; 4.B.154.236; 4.B.154.237; 4.B.154.238; 4.B.154.239; 4.B.154.154; 4.B.154.157; 4.B.154.166; 4.B.154.169; 4.B.154.172; 4.B.154.175; 4.B.154.240; 4.B.154.244; 4.B.157.228; 4.B.157.229; 4.B.157.23Q; 4.B.157.231; 4.B.157.236; 4.B.157.237; 4.B.157.238; 4.B.157.239; 4.B.157.154; 4.B.157.157; 4.B.157.166; 4.B.157.169; 4.B.157.172; 4.B.157.175; 4.B.157.240; 4.B.157.244; 4.B.166.228; 4.B.166.229; 4.B.166.230; 4.B.166.231; 4.B.166.236; 4.B.166.237; 4.B.166.238; 4.B.166.239; 4.B.166.154; 4.B.166.157; 4.B.166.166; 4.B.166.169; 4.B.166.172; 4.B.166.175; 4.B.166.240; 4.B.166.244; 4.B.169.228; 4.B.169.229; 4.B.169.230; 4.B.169.231; 4.B.169.236; 4.B.169.237; 4.B.169.238; 4.B.169.239; 4.B.169.154; 4.B.169.157; 4.B.169.166; 4.B.169.169; 4.B.169.172; 4.B.169.175; 4.B.169.240; 4.B.169.244; 4.B.172.228; 4.B.172.229; 4.B.172.230; 4.B.172.231; 4.B.172.236; 4.B.172.237; 4.B.172.238; 4.B.172.239; 4.B.172.154; 4.B.172.157; 4.B.172.166; 4.B.172.169; 4.B.172.172; 4.B.172.175; 4.B.172.240; 4.B.172.244; 4.B.175.228; 4.B.175.229; 4.B.175.230; 4.B.175.231; 4.B.175.236; 4.B.175.237; 4.B.175.238; 4.B.175.239; 4.B.175.154; 4.B.175.157; 4.B.175.166; 4.B.175.169; 4.B.175.172; 4.B.175.175; 4.B.175.240; 4.B.175.244; 4.B.240.228; 4.B.240.229; 4.B.240.230; 4.B.240.231; 4.B.240.236; 4.B.240.237; 4.B.240.238; 4.B.240.239; 4.B.240.154; 4.B.240.157; 4.B.240.166; 4.B.240.169; 4.B.240.172; 4.B.240.175; 4.B.240.240; 4.B.240.244; 4.B.244.228; 4.B.244.229; 4.B.244.230; 4.B.244.231; 4.B.244.236; 4.B.244.237; 4.B.244.238; 4.B.244.239; 4.B.244.154; 4.B.244.157; 4.B.244.166; 4.B.244.169; 4.B.244.172; 4.B.244.175; 4.B.244.240; 4.B.244.244;

Prodrugs of 4.D

4.D.228.228; 4.D.228.229; 4.D.228.230; 4.D.228.231; 4.D.228.236; 4.D.228.237; 4.D.228.238; 4.D.228.239; 4.D.228.154; 4.D.228.157; 4.D.228.166; 4.D.228.169; 4.D.228.172; 4.D.228.175; 4.D.228.240; 4.D.228.244; 4.D.229.228; 4.D.229.229; 4.D.229.230; 4.D.229.231; 4.D.229.236; 4.D.229.237; 4.D.229.238; 4.D.229.239; 4.D.229.154; 4.D.229.157; 4.D.229.166; 4.D.229.169; 4.D.229.172; 4.D.229.175; 4.D.229.240; 4.D.229.244; 4.D.230.228; 4.D.230.229; 4.D.230.230; 4.D.230.231; 4.D.230.236; 4.D.230.237; 4.D.230.238; 4.D.230.239; 4.D.230.154; 4.D.230.157; 4.D.230.166; 4.D.230.169; 4.D.230.172; 4.D.230.175; 4.D.230.240; 4.D.230.244; 4.D.231.228; 4.D.231.229; 4.D.231.230; 4.D.231.231; 4.D.231.236; 4.D.231.237; 4.D.231.238; 4.D.231.239; 4.D.231.154; 4.D.231.157; 4.D.231.166; 4.D.231.169; 4.D.231.172; 4.D.231.175; 4.D.231.240; 4.D.231.244; 4.D.236.228; 4.D.236.229; 4.D.236.230; 4.D.236.231; 4.D.236.236; 4.D.236.237; 4.D.236.238; 4.D.236.239; 4.D.236.154; 4.D.236.157; 4.D.236.166; 4.D.236.169; 4.D.236.172; 4.D.236.175; 4.D.236.240; 4.D.236.244; 4.D.237.228; 4.D.237.229; 4.D.237.230; 4.D.237.231; 4.D.237.236; 4.D.237.237; 4.D.237.238; 4.D.237.239; 4.D.237.154; 4.D.237.157; 4.D.237.166; 4.D.237.169; 4.D.237.172; 4.D.237.175; 4.D.237.240; 4.D.237.244; 4.D.238.228; 4.D.238.229; 4.D.238.230; 4.D.238.231; 4.D.238.236; 4.D.238.237; 4.D.238.238; 4.D.238.239; 4.D.238.154; 4.D.238.157; 4.D.238.166; 4.D.238.169; 4.D.238.172; 4.D.238.175; 4.D.238.240; 4.D.238.244; 4.D.239.228; 4.D.239.229; 4.D.239.230; 4.D.239.231; 4.D.239.236; 4.D.239.237; 4.D.239.238; 4.D.239.239; 4.D.239.154; 4.D.239.157; 4.D.239.166; 4.D.239.169; 4.D.239.172; 4.D.239.175; 4.D.239.240; 4.D.239.244; 4.D.154.228; 4.D.154.229; 4.D.154.230; 4.D.154.231; 4.D.154.236; 4.D.154.237; 4.D.154.238; 4.D.154.239; 4.D.154.154; 4.D.154.157; 4.D.154.166; 4.D.154.169; 4.D.154.172; 4.D.154.175; 4.D.154.240; 4.D.154.244; 4.D.157.228; 4.D.157.229; 4.D.157.230; 4.D.157.231; 4.D.157.236; 4.D.157.237; 4.D.157.238; 4.D.157.239; 4.D.157.154; 4.D.157.157; 4.D.157.166; 4.D.157.169; 4.D.157.172; 4.D.157.175; 4.D.157.240; 4.D.157.244; 4.D.166.228; 4.D.166.229; 4.D.166.230; 4.D.166.231; 4.D.166.236; 4.D.166.237; 4.D.166.238; 4.D.166.239; 4.D.166.154; 4.D.166.157; 4.D.166.166; 4.D.166.169; 4.D.166.172; 4.D.166.175; 4.D.166.240; 4.D.166.244; 4.D.169.228; 4.D.169.229; 4.D.169.230; 4.D.169.231; 4.D.169.236; 4.D.169.237; 4.D.169.238; 4.D.169.239; 4.D.169.154; 4.D.169.157; 4.D.169.166; 4.D.169.169; 4.D.169.172; 4.D.169.175; 4.D.169.240; 4.D.169.244; 4.D.172.228; 4.D.172.229; 4.D.172.230; 4.D.172.231; 4.D.172.236; 4.D.172.237; 4.D.172.238; 4.D.172.239; 4.D.172.154; 4.D.172.157; 4.D.172.166; 4.D.172.169; 4.D.172.172; 4.D.172.175; 4.D.172.240; 4.D.172.244; 4.D.175.228; 4.D.175.229; 4.D.175.230; 4.D.175.231; 4.D.175.236; 4.D.175.237; 4.D.175.238; 4.D.175.239; 4.D.175.154; 4.D.175.157; 4.D.175.166; 4.D.175.169; 4.D.175.172; 4.D.175.175; 4.D.175.240; 4.D.175.244; 4.D.240.228; 4.D.240.229; 4.D.240.230; 4.D.240.231; 4.D.240.236; 4.D.240.237; 4.D.240.238; 4.D.240.239; 4.D.240.154; 4.D.240.157; 4.D.240.166; 4.D.240.169; 4.D.240.172; 4.D.240.175; 4.D.240.240; 4.D.240.244; 4.D.244.228; 4.D.244.229; 4.D.244.230; 4.D.244.231; 4.D.244.236; 4.D.244.237; 4.D.244.238; 4.D.244.239; 4.D.244.154; 4.D.244.157; 4.D.244.166; 4.D.244.169; 4.D.244.172; 4.D.244.175; 4.D.244.240; 4.D.244.244;

Prodrugs of 4.AB

4.AB.228.228; 4.AB.228.229; 4.AB.228.230; 4.AB.228.231; 4.AB.228.236; 4.AB.228.237; 4.AB.228.238; 4.AB.228.239; 4.AB.228.154; 4.AB.228.157; 4.AB.228.166; 4.AB.228.169; 4.AB.228.172; 4.AB.228.175; 4.AB.228.240; 4.AB.228.244; 4.AB.229.228; 4.AB.229.229; 4.AB.229.230; 4.AB.229.231; 4.AB.229.236; 4.AB.229.237; 4.AB.229.238; 4.AB.229.239; 4.AB.229.154; 4.AB.229.157; 4.AB.229.166; 4.AB.229.169; 4.AB.229.172; 4.AB.229.175; 4.AB.229.240; 4.AB.229.244; 4.AB.230.228; 4.AB.230.229; 4.AB.230.230; 4.AB.230.231; 4.AB.230.236; 4.AB.230.237; 4.AB.230.238; 4.AB.230.239; 4.AB.230.154; 4.AB.230.157; 4.AB.230.166; 4.AB.230.169; 4.AB.230.172; 4.AB.230.175; 4.AB.230.240; 4.AB.230.244; 4.AB.231.228; 4.AB.231.229; 4.AB.231.230; 4.AB.231.231; 4.AB.231.236; 4.AB.231.237; 4.AB.231.238; 4.AB.231.239; 4.AB.231.154; 4.AB.231.157; 4.AB.231.166; 4.AB.231.169; 4.AB.231.172; 4.AB.231.175; 4.AB.231.240; 4.AB.231.244; 4.AB.236.228; 4.AB.236.229; 4.AB.236.230; 4.AB.236.231; 4.AB.236.236; 4.AB.236.237; 4.AB.236.238; 4.AB.236.239; 4.AB.236.154; 4.AB.236-157; 4.AB.236-166; 4.AB.236.169; 4.AB.236.172; 4.AB.236.175; 4.AB.236.240; 4.AB.236.244; 4.AB.237.228; 4.AB.237.229; 4.AB.237.230; 4.AB.237.231; 4.AB.237.236; 4.AB.237.237; 4.AB.237.238; 4.AB.237.239; 4.AB.237.154; 4.AB.237.157; 4.AB.237.166; 4.AB.237.169; 4.AB.237.172; 4.AB.237.175; 4.AB.237.240; 4.AB.237.244; 4.AB.238.228; 4.AB.238.229; 4.AB.238.230; 4.AB.238.231; 4.AB.238.236; 4.AB.238.237; 4.AB.238.238; 4.AB.238.239; 4.AB.238.154; 4.AB.238.157; 4.AB.238.166; 4.AB.238.169; 4.AB.238.172; 4.AB.238.175; 4.AB.238.240; 4.AB.238.244; 4.AB.239.228; 4.AB.239.229; 4.AB.239.230; 4.AB.239.231; 4.AB.239.236; 4.AB.239.237; 4.AB.239.238; 4.AB.239.239; 4.AB.239.154; 4.AB.239.157; 4.AB.239.166; 4.AB.239.169; 4.AB.239.172; 4.AB.239.175; 4.AB.239.240; 4.AB.239.244; 4.AB.154.228; 4.AB.154.229; 4.AB.154.230; 4.AB.154.231; 4.AB.154.236; 4.AB.154.237; 4.AB.154.238; 4.AB.154.239; 4.AB.154.154; 4.AB.154.157; 4.AB.154.166; 4.AB.154.169; 4.AB.154.172; 4.AB.154.175; 4.AB.154.240; 4.AB.154.244; 4.AB.157.228; 4.AB.157.229; 4.AB.157.230; 4.AB.157.231; 4.AB.157.236; 4.AB.157.237; 4.AB.157.238; 4.AB.157.239; 4.AB.157.154; 4.AB.157.157; 4.AB.157.166; 4.AB.157.169; 4.AB.157.172; 4.AB.157.175; 4.AB.157.240; 4.AB.157.244; 4.AB.166.228; 4.AB.166.229; 4.AB.166.23Q; 4.AB.166.231; 4.AB.166.236; 4.AB.166.237; 4.AB.166.238; 4.AB.166.239; 4.AB.166.154; 4.AB.166.157; 4.AB.166.166; 4.AB.166.169; 4.AB.166.172; 4.AB.166.175; 4.AB.166.240; 4.AB.166.244; 4.AB.169.228; 4.AB.169.229; 4.AB.169.230; 4.AB.169.231; 4.AB.169.236; 4.AB.169.237; 4.AB.169.238; 4.AB.169.239; 4.AB.169.154; 4.AB.169.157; 4.AB.169.166; 4.AB.169.169; 4.AB.169.172; 4.AB.169.175; 4.AB.169.240; 4.AB.169.244; 4.AB.172.228; 4.AB.172.229; 4.AB.172.230; 4.AB.172.231; 4.AB.172.236; 4.AB.172.237; 4.AB.172.238; 4.AB.172.239; 4.AB.172.154; 4.AB.172.157; 4.AB.172.166; 4.AB.172.169; 4.AB.172.172; 4.AB.172.175; 4.AB.172.240; 4.AB.172.244; 4.AB.175.228; 4.AB.175.229; 4.AB.175.230; 4.AB.175.231; 4.AB.175.236; 4.AB.175.237; 4.AB.175.238; 4.AB.175.239; 4.AB.175.154; 4.AB.175.157; 4.AB.175.166; 4.AB.175.169; 4.AB.175.172; 4.AB.175.175; 4.AB.175.240; 4.AB.175.244; 4.AB.240.228; 4.AB.240.229; 4.AB.240.230; 4.AB.24Q.231; 4.AB.240.236; 4.AB.240.237; 4.AB.240.238; 4.AB.240.239; 4.AB.240.154; 4.AB.240.157; 4.AB.240.166; 4.AB.240.169; 4.AB.240.172; 4.AB.240.175; 4.AB.240.240; 4.AB.240.244; 4.AB.244.228; 4.AB.244.229; 4.AB.244.230; 4.AB.244.231; 4.AB.244.236; 4.AB.244.237; 4.AB.244.238; 4.AB.244.239; 4.AB.244.154; 4.AB.244.157; 4.AB.244.166; 4.AB.244.169; 4.AB.244.172; 4.AB.244.175; 4.AB.244.240; 4.AB.244.244;

Prodrugs of 4.BI

4.BI.228.228; 4.BI.228.229; 4.BI.228.230; 4.BI.228.231; 4.BI.228.236; 4.BI.228.237; 4.BI.228.238; 4.BI.228.239; 4.BI.228.154; 4.BI.228.157; 4.BI.228.166; 4.BI.228.169; 4.BI.228.172; 4.BI.228.175; 4.BI.228.240; 4.BI.228.244; 4.BI.229.228; 4.BI.229.229; 4.BI.229.230; 4.BI.229.231; 4.BI.229.236; 4.BI.229.237; 4.BI.229.238; 4.BI.229.239; 4.BI.229.154; 4.BI.229.157; 4.BI.229.166; 4.BI.229.169; 4.BI.229.172; 4.BI.229.175; 4.BI.229.240; 4.BI.229.244; 4.BI.230.228; 4.BI.23Q.229; 4.BI.230.230; 4.BI.230.231; 4.BI.230.236; 4.BI.230.237; 4.BI.230.238; 4.BI.230.239; 4.BI.230.154; 4.BI.230.157; 4.BI.230.166; 4.BI.230.169; 4.BI.230.172; 4.BI.230.175; 4.BI.230.240; 4.BI.230.244; 4.BI.231.228; 4.BI.231.229; 4.BI.231.230; 4.BI.231.231; 4.BI.231.236; 4.BI.231.237; 4.BI.231.238; 4.BI.231.239; 4.BI.231.154; 4.BI.231.157; 4.BI.231.166; 4.BI.231.169; 4.BI.231.172; 4.BI.231.175; 4.BI.231.240; 4.BI.231.244; 4.BI.236.228; 4.BI.236.229; 4.BI.236.230; 4.BI.236.231; 4.BI.236.236; 4.BI.236.237; 4.BI.236.238; 4.BI.236.239; 4.BI.236.154; 4.BI.236.157; 4.BI.236.166; 4.BI.236.169; 4.BI.236.172; 4.BI.236.175; 4.BI.236.240; 4.BI.236.244; 4.BI.237.228; 4.BI.237.229; 4.BI.237.230; 4.BI.237.231; 4.BI.237.236; 4.BI.237.237; 4.BI.237.238; 4.BI.237.239; 4.BI.237.154; 4.BI.237.157; 4.BI.237.166; 4.BI.237.169; 4.BI.237.172; 4.BI.237.175; 4.BI.237.240; 4.BI.237.244; 4.BI.238.228; 4.BI.238.229; 4.BI.238.230; 4.BL238.231; 4.BI.238.236; 4.BI.238.237; 4.BI.238.238; 4.BI.238.239; 4.BI.238.154; 4.BI.238.157; 4.BI.238.166; 4.BI.238.169; 4.BI.238.172; 4.BI.238.175; 4.BI.238.240; 4.BI.238.244; 4.BI.239.228; 4.BI.239.229; 4.BI.239.230; 4.BI.239.231; 4.BI.239.236; 4.BI.239.237; 4.BI.239.238; 4.BI.239.239; 4.BI.239.154; 4.BI.239.157; 4.BI.239.166; 4.BI.239.169; 4.BI.239.172; 4.BI.239.175; 4.BL239.240; 4.BI.239.244; 4.BL154.228; 4.BI.154.229; 4.BI.154.230; 4.BI.154.231; 4.BI.154.236; 4.BI.154.237; 4.BI.154.238; 4.BI.154.239; 4.BI.154.154; 4.BI.154.157; 4.BI.154.166; 4.BI.154.169; 4.BI.154.172; 4.BI.154.175; 4.BI.154.240; 4.BI.154.244; 4.BI.157.228; 4.BI.157.229; 4.BI.157.230; 4.BI.157.231; 4.BI.157.236; 4.BI.157.237; 4.BI.157.238; 4.BI.157.239; 4.BI.157.154; 4.BI.157.157; 4.BI.157.166; 4.BI.157.169; 4.BI.157.172; 4.BI.157.175; 4.BI.157.240; 4.BL157.244; 4.BI.166.228; 4.BI.166.229; 4.BI.166.230; 4.BI.166.231; 4.BI.166.236; 4.BL166.237; 4.BI.166.238; 4.BI.166.239; 4.BI.166.154; 4.BI.166.157; 4.BI.166.166; 4.BI.166.169; 4.BI.166.172; 4.BI.166.175; 4.BI.166.240; 4.BI.166.244; 4.BI.169.228; 4.BI.169.229; 4.BI.169.230; 4.BI.169.231; 4.BI.169.236; 4.BI.169.237; 4.BI.169.238; 4.BI.169.239; 4.BI.169.154; 4.BI.169.157; 4.BI.169.166; 4.BI.169.169; 4.BI.169.172; 4.BI.169.175; 4.BI.169.240; 4.BI.169.244; 4.BI.172.228; 4.BI.172.229; 4.BI.172.230; 4.BI.172.231; 4.BI.172.236; 4.BI.172.237; 4.BI.172.238; 4.BI.172.239; 4.BI.172.154; 4.BI.172.157; 4.BL172.166; 4.BI.172.169; 4.BI.172.172; 4.BI.172.175; 4.BI.172.240; 4.BI.172.244; 4.BI.175.228; 4.BI.175.229; 4.BI.175.230; 4.BI.175.231; 4.BI.175.236; 4.BI.175.237; 4.BI.175.238; 4.BI.175.239; 4.BI.175.154; 4.BI.175.157; 4.BI.175.166; 4.BI.175.169; 4.BI.175.172; 4.BI.175.175; 4.BI.175.240; 4.BI.175.244; 4.BI.240.228; 4.BI.240.229; 4.BI.240.230; 4.BI.240.231; 4.BI.240.236; 4.BI.240.237; 4.BI.240.238; 4.BI.240.239; 4.BI.240.154; 4.BI.240.157; 4.BI.240.166; 4.BI.240.169; 4.BI.240.172; 4.BI.240.175; 4.BI.240.240; 4.BI.240.244; 4.BI.244.228; 4.BL244.229; 4.BI.244.230; 4.BI.244.231; 4.BI.244.236; 4.BI.244.237; 4.BI.244.238; 4.BL244.239; 4.BI.244.154; 4.BI.244.157; 4.BI.244.166; 4.BI.244.169; 4.BI.244.172; 4.BI.244.175; 4.BI.244.240; 4.BI.244.244;

Prodrugs of 4.1

4.1.228.228; 4.1.228.229; 4.1.228.230; 4.1.228.231; 4.1.228.236; 4.1.228.237; 4.1.228.238; 4.1.228.239; 4.1.228.154; 4.1.228.157; 4.1.228.166; 4.1.228.169; 4.1.228.172; 4.1.228.175; 4.1.228.240; 4.1.228.244; 4.1.229.228; 4.1.229.229; 4.1.229.230; 4.1.229.231; 4.1.229.236; 4.1.229.237; 4.1.229.238; 4.1.229.239; 4.1.229.154; 4.1.229.157; 4.1.229.166; 4.1.229.169; 4.1.229.172; 4.1.229.175; 4.1.229.240; 4.1.229.244; 4.1.230.228; 4.1.230.229; 4.1.230.230; 4.1.230.231; 4.1.230.236; 4.1.230.237; 4.1.230.238; 4.1.230.239; 4.1.230.154; 4.1.230.157; 4.1.230.166; 4.1.230.169; 4.1.230.172; 4.1.230.175; 4.1.230.240; 4.1.230.244; 4.1.231.228; 4.1.231.229; 4.1.231.230; 4.1.231.231; 4.1.231.236; 4.1.231.237; 4.1.231.238; 4.1.231.239; 4.1.231.154; 4.1.231.157; 4.1.231.166; 4.1.231.169; 4.1.231.172; 4.1.231.175; 4.1.231.240; 4.1.231.244; 4.1.236.228; 4.1.236-229; 4.1.236.230; 4.1.236.231; 4.1.236.236; 4.1.236.237; 4.1.236.238; 4.1.236.239; 4.1.236.154; 4.1.236.157; 4.1.236.166; 4.1.236.169; 4.1.236.172; 4.1.236.175; 4.1.236.240; 4.1.236.244; 4.1.237.228; 4.1.237.229; 4.1.237.230; 4.1.237.231; 4.1.237.236; 4.1.237.237; 4.1.237.238; 4.1.237.239; 4.1.237.154; 4.1.237.157; 4.1.237.166; 4.1.237.169; 4.1.237.172; 4.1.237.175; 4.1.237.240; 4.1.237.244; 4.1.238.228; 4.1.238.229; 4.1.238.230; 4.1.238.231; 4.1.238.236; 4.1.238.237; 4.1.238.238; 4.1.238.239; 4.1.238.154; 4.1.238.157; 4.1.238.166; 4.1.238.169; 4.1.238.172; 4.1.238.175; 4.1.238.240; 4.1.238.244; 4.1.239.228; 4.1.239.229; 4.1.239.230; 4.1.239.231; 4.1.239.236; 4.1.239.237; 4.1.239.238; 4.1.239.239; 4.1.239.154; 4.1.239.157; 4.1.239.166; 4.1.239.169; 4.1.239.172; 4.1.239.175; 4.1.239.240; 4.1.239.244; 4.1.154.228; 4.1.154.229; 4.1.154.230; 4.1.154.231; 4.1.154.236; 4.1.154.237; 4.1.154.238; 4.1.154.239; 4.1.154.154; 4.1.154.157; 4.1.154.166; 4.1.154.169; 4.1.154.172; 4.1.154.175; 4.1.154.240; 4.1.154.244; 4.1.157.228; 4.1.157.229; 4.1.157.230; 4.1.157.231; 4.1.157.236; 4.1.157.237; 4.1.157.238; 4.1.157.239; 4.1.157.154; 4.1.157.157; 4.1.157.166; 4.1.157.169; 4.1.157.172; 4.1.157.175; 4.1.157.240; 4.1.157.244; 4.1.166.228; 4.1.166.229; 4.1.166.230; 4.1.166.231; 4.1.166.236; 4.1.166.237; 4.1.166.238; 4.1.166.239; 4.1.166.154; 4.1.166.157; 4.1.166.166; 4.1.166.169; 4.1.166.172; 4.1.166.175; 4.1.166.240; 4.1.166.244; 4.1.169.228; 4.1.169.229; 4.1.169.230; 4.1.169.231; 4.1.169.236; 4.1.169.237; 4.1.169.238; 4.1.169.239; 4.1.169.154; 4.1.169.157; 4.1.169.166; 4.1.169.169; 4.1.169.172; 4.1.169.175; 4.1.169.240; 4.1.169.244; 4.1.172.228; 4.1.172.229; 4.1.172.230; 4.1.172.231; 4.1.172.236; 4.1.172.237; 4.1.172.238; 4.1.172.239; 4.1.172.154; 4.1.172.157; 4.1.172.166; 4.1.172.169; 4.1.172.172; 4.1.172.175; 4.1.172.240; 4.1.172.244; 4.1.175.228; 4.1.175.229; 4.1.175.230; 4.1.175.231; 4.1.175.236; 4.1.175.237; 4.1.175.238; 4.1.175.239; 4.1.175.154; 4.1.175.157; 4.1.175.166; 4.1.175.169; 4.1.175.172; 4.1.175.175; 4.1.175.240; 4.1.175.244; 4.1.240.228; 4.1.240.229; 4.1.240.230; 4.1.240.231; 4.1.240.236; 4.1.240.237; 4.1.240.238; 4.1.240.239; 4.1.240.154; 4.1.240.157; 4.1.240.166; 4.1.240.169; 4.1.240.172; 4.1.240.175; 4.1.240.240; 4.1.240.244; 4.1.244.228; 4.1.244.229; 4.1.244.230; 4.1.244.231; 4.1.244.236; 4.1.244.237; 4.1.244.238; 4.1.244.239; 4.1.244.154; 4.1.244.157; 4.1.244.166; 4.1.244.169; 4.1.244.172; 4.1.244.175; 4.1.244.240; 4.1.244.244;

Prodrugs of 4.T

4.J.228.228; 4.J.228.229; 4.J.228.230; 4.J.228.231; 4.J.228.236; 4.J.228.237; 4.J.228.238; 4.J.228.239; 4.J.228.154; 4.J.228.157; 4.J.228.166; 4.J.228.169; 4.J.228.172; 4.J.228.175; 4.J.228.24Q; 4.J.228.244; 4J.229.228; 4.J.229.229; 4.J.229.230; 4.J.229.231; 4J.229.236; 4J.229.237; 4J.229.238; 4J.229.239; 4J.229.154; 4J.229.157; 4.J.229.166; 4J.229.169; 4J.229.172; 4J.229.175; 4 J.229.240; 4J.229.244; 4J.230.228; 4J.230.229; 4J.230.230; 4J.230.231; 4J.230.236; 4J.230.237; 4J.230.238; 4J.230.239; 4J.230.154; 4 J.230.157; 4J.230.166; 4.J.230.169; 4J.230.172; 4J.230.175; 4J.230.240; 4J.230.244; 4J.231.228; 4J.231.229; 4J.231.230; 4J.231.231; 4J.231.236; 4J.231.237; 4J.231.238; 4J.231.239; 4J.231.154; 4J.231.157; 4J.231.166; 4J.231.169; 4J.231.172; 4J.231.175; 4J.231.240; 4J.231.244; 4J.236.228; 4J.236.229; 4J.236.230; 4J.236.231; 4J.236.236; 4.J.236.237; 4J.236.238; 4J.236.239; 4.J.236.154; 4J.236.157; 4J.236.166; 4J.236.169; 4J.236.172; 4J.236.175; 4.J.236.240; 4J.236.244; 4J.237.228; 4J.237.229; 4J.237.230; 4J.237.231; 4J.237.236; 4.J.237.237; 4J.237.238; 4 J.237.239; 4J.237.154; 4J.237.157; 4J.237.166; 4.J.237.169; 4.J.237.172; 4.J.237.175; 4J.237.240; 4.J.237.244; 4.J.238.228; 4.J.238.229; 4.J.238.230; 4.J.238.231; 4.J.238.236; 4.J.238.237; 4.J.238.238; 4.J.238.239; 4.J.238.154; 4.J.238.157; 4.J.238.166; 4.J.238.169; 4.J.238.172; 4.J.238.175; 4.J.238.240; 4.J.238.244; 4.J.239.228; 4.J.239.229; 4.J.239.230; 4.J.239.231; 4.J.239.236; 4.J.239.237; 4.J.239.238; 4.J.239.239; 4.J.239.154; 4.J.239.157; 4.J.239.166; 4.J.239.169; 4.J.239.172; 4.J.239.175; 4 J.239.240; 4.J.239.244; 4.J.154.228; 4.J.154.229; 4.J.154.230; 4.J.154.231; 4.J.154.236; 4.J.154.237; 4.J.154.238; 4.J.154.239; 4.J.154.154; 4.J.154.157; 4.J.154.166; 4.J.154.169; 4.J.154.172; 4.J.154.175; 4.J.154.240; 4.J.154.244; 4J.157.228; 4J.157.229; 4J.157.230; 4J.157.231; 4J.157.236; 4J.157.237; 4J.157.238; 4J.157.239; 4J.157.154; 4J.157.157; 4J.157.166; 4J.157.169; 4J.157.172; 4J.157.175; 4J.157.240; 4 J.157.244; 4J.166.228; 4J.166.229; 4 J.166.230; 4J.166.231; 4J.166.236; 4J.166.237; 4J.166.238; 4J.166.239; 4J.166.154; 4 J.166.157; 4 J.166.166; 4J.166.169; 4J.166.172; 4J.166.175; 4.J.166.240; 4J.166.244; 4J.169.228; 4J.169.229; 4J.169.230; 4J.169.231; 4J.169.236; 4.J.169.237; 4J.169.238; 4J.169.239; 4J.169.154; 4 J.169.157; 4J.169.166; 4J.169.169; 4J.169.172; 4J.169.175; 4J.169.240; 4J.169.244; 4J.172.228; 4 J.172.229; 4J.172.230; 4 J.172.231; 4J.172.236; 4J.172.237; 4J.172.238; 4 J.172.239; 4J.172.154; 4.J.172.157; 4J.172.166; 4J.172.169; 4J.172.172; 4J.172.175; 4J.172.240; 4J.172.244; 4J.175.228; 4J.175.229; 4J.175.230; 4J.175.231; 4J.175.236; 4J.175.237; 4J.175.238; 4J.175.239; 4J.175.154; 4J.175.157; 4J.175.166; 4J.175.169; 4J.175.172; 4.J.175.175; 4J.175.240; 4J.175.244; 4J.24Q.228; 4J.240.229; 4J.240.230; 4J.240.231; 4J.240.236; 4J.240.237; 4J.240.238; 4J.240.239; 4J.240.154; 4J.240.157; 4J.240.166; 4J.240.169; 4J.240.172; 4J.240.175; 4 J.240.240; 4 J.240.244; 4 J.244.228; 4 J.244.229; 4J.244.230; 4 J.244.231; 4J.244.236; 4J.244.237; 4J.244.238; 4J.244.239; 4J.244.154; 4J.244.157; 4J.244.166; 4J.244.169; 4J.244.172; 4J.244.175; 4J.244.240; 4J.244.244;

Prodrugs of 4.L

4.L.228.228; 4X.228.229; 4.L.228.230; 4.L.228.231; 4.L.228.236; 4.L.228.237; 4.L.228.238; 4.L.228.239; 4.L.228.154; 4.L.228.157; 4.L.228.166; 4.L.228.169; 4.L.228.172; 4.L.228.175; 4.L.228.240; 4.L.228.244; 4.L.229.228; 4.L.229.229; 4.L.229.230; 4.L.229.231; 4.L.229.236; 4.L.229.237; 4.L.229.238; 4.L.229.239; 4.L.229.154; 4.L.229.157; 4.L.229.166; 4X.229.169; 4.L.229.172; 4X.229.175; 4.L.229.240; 4X.229.244; 4X.230.228; 4X.230.229; 4X.230.230; 4X.230.231; 4X.230.236; 4X.230.237; 4X.230.238; 4X.230.239; 4X.230.154; 4X.230.157; 4X.230.166; 4X.230.169; 4X.230.172; 4X.230.175; 4X.230.240; 4X.230.244; 4X.231.228; 4X.231.229; 4X.231.230; 4X.231.231; 4X.231.236; 4X.231.237; 4X.231.238; 4X.231.239; 4X.231.154; 4X.231.157; 4X.231.166; 4X.231.169; 4X.231.172; 4X.231.175; 4X.231.240; 4X.231.244; 4.L.236.228; 4X.236.229; 4X.236.230; 4X.236.231; 4X.236.236; 4X.236.237; 4X.236.238; 4X.236.239; 4X.236.154; 4X.236.157; 4X.236.166; 4X.236.169; 4X.236.172; 4.L.236.175; 4X.236.240; 4X.236.244; 4X.237.228; 4X.237.229; 4X.237.230; 4.L.237.231; 4X.237.236; 4X.237.237; 4X.237.238; 4X.237.239; 4X.237.154; 4X.237.157; 4X.237.166; 4.L.237.169; 4X.237.172; 4X.237.175; 4X.237.240; 4.L.237.244; 4X.238.228; 4X.238.229; 4X.238.230; 4X.238.231; 4X.238.236; 4X.238.237; 4X.238.238; 4X.238.239; 4X.238.154; 4X.238.157; 4X.238.166; 4X.238.169; 4X.238.172; 4X.238.175; 4X.238.240; 4X.238.244; 4X.239.228; 4X.239.229; 4X.239.230; 4X.239.231; 4X.239.236; 4X.239.237; 4X.239.238; 4X.239.239; 4.L.239.154; 4.L.239.157; 4.L.239.166; 4.L.239.169; 4.L.239.172; 4.L.239.175; 4.L.239.240; 4.L.239.244; 4.L.154.228; 4.L.154.229; 4.L.154.230; 4.L.154.231; 4.L.154.236; 4.L.154.237; 4.L.154.238; 4.L.154.239; 4.L.154.154; 4.L.154.157; 4.L.154.166; 4.L.154.169; 4.L.154.172; 4.L.154.175; 4.L.154.240; 4.L.154.244; 4.L.157.228; 4.L.157.229; 4.L.157.230; 4.L.157.231; 4.L.157.236; 4.L.157.237; 4.L.157.238; 4.L.157.239; 4.L.157.154; 4.L.157.157; 4.L.157.166; 4.L.157.169; 4.L.157.172; 4.L.157.175; 4.L.157.240; 4.L.157.244; 4.L.166.228; 4.L.166.229; 4.L.166.230; 4.L.166.231; 4.L.166.236; 4.L.166.237; 4.L.166.238; 4.L.166.239; 4.L.166.154; 4.L.166.157; 4.L.166.166; 4.L.166.169; 4.L.166.172; 4.L.166.175; 4.L.166.240; 4.L.166.244; 4X.169.228; 4.L.169.229; 4.L.169.230; 4.L.169.231; 4.L.169.236; 4.L.169.237; 4.L.169.238; 4.L.169.239; 4.L.169.154; 4.L.169.157; 4.L.169.166; 4.L.169.169; 4.L.169.172; 4.L.169.175; 4.L.169.240; 4.L.169.244; 4.L.172.228; 4.L.172.229; 4.L.172.230; 4.L.172.231; 4.L.172.236; 4.L.172.237; 4.L.172.238; 4.L.172.239; 4.L.172.154; 4.L.172.157; 4.L.172.166; 4.L.172.169; 4.L.172.172; 4.L.172.175; 4.L.172.240; 4.L.172.244; 4.L.175.228; 4.L.175.229; 4.L.175.230; 4.L.175.231; 4.L.175.236; 4.L.175.237; 4.L.175.238; 4.L.175.239; 4.L.175.154; 4.L.175.157; 4.L.175.166; 4.L.175.169; 4.L.175.172; 4.L.175.175; 4.L.175.240; 4.L.175.244; 4.L.240.228; 4.L.240.229; 4.L.240.230; 4.L.240.231; 4.L.240.236; 4.L.240.237; 4.L.240.238; 4.L.240.239; 4.L.240.154; 4.L.240.157; 4.L.240.166; 4.L.240.169; 4.L.240.172; 4.L.240.175; 4.L.240.240; 4.L.240.244; 4.L.244.228; 4.L.244.229; 4.L.244.230; 4.L.244.231; 4.L.244.236; 4.L.244.237; 4.L.244.238; 4.L.244.239; 4.L.244.154; 4.L.244.157; 4.L.244.166; 4.L.244.169; 4.L.244.172; 4.L.244.175; 4.L.244.240; 4.L.244.244;

Prodrugs of 4.O

4.O.228.228; 4.O.228.229; 4.O.228.230; 4.O.228.231; 4.O.228.236; 4.O.228.237; 4.O.228.238; 4.O.228.239; 4.O.228.154; 4.O.228.157; 4.O.228.166; 4.O.228.169; 4.O.228.172; 4.O.228.175; 4.O.228.24Q; 4.O.228.244; 4.O.229.228; 4.O.229.229; 4.O.229.230; 4.O.229.231; 4.O.229.236; 4.O.229.237; 4.O.229.238; 4.O.229.239; 4.O.229.154; 4.O.229.157; 4.O.229.166; 4.O.229.169; 4.O.229.172; 4.O.229.175; 4.O.229.240; 4.O.229.244; 4.O.23Q.228; 4.O.230.229; 4.O.230.230; 4.O.230.231; 4.O.230.236; 4.O.230.237; 4.O.230.238; 4.O.230.239; 4.O.230.154; 4.O.230.157; 4.O.230.166; 4.O.230.169; 4.O.230.172; 4.O.230.175; 4.O.230.240; 4.O.230.244; 4.O.231.228; 4.O.231.229; 4.O.231.230; 4.O.231.231; 4.O.231.236; 4.O.231.237; 4.O.231.238; 4.O.231.239; 4.O.231.154; 4.O.231.157; 4.O.231.166; 4.O.231.169; 4.O.231.172; 4.O.231.175; 4.O.231.240; 4.O.231.244; 4.O.236.228; 4.O.236.229; 4.O.236.230; 4.O.236.231; 4.O.236.236; 4.O.236.237; 4.O.236.238; 4.O.236.239; 4.O.236.154; 4.O.236.157; 4.O.236.166; 4.O.236.169; 4.O.236.172; 4.O.236.175; 4.O.236.240; 4.O.236.244; 4.O.237.228; 4.O.237.229; 4.O.237.230; 4.O.237.231; 4.O.237.236; 4.O.237.237; 4.O.237.238; 4.O.237.239; 4.O.237.154; 4.O.237.157; 4.O.237.166; 4.O.237.169; 4.O.237.172; 4.O.237.175; 4.O.237.240; 4.O.237.244; 4.O.238.228; 4.O.238.229; 4.O.238.230; 4.O.238.231; 4.O.238.236; 4.O.238.237; 4.O.238.238; 4.O.238.239; 4.O.238.154; 4.O.238.157; 4.O.238.166; 4.O.238.169; 4.O.238.172; 4.O.238.175; 4.O.238.240; 4.O.238.244; 4.O.239.228; 4.O.239.229; 4.O.239.230; 4.O.239.231; 4.O.239.236; 4.O.239.237; 4.O.239.238; 4.O.239.239; 4.O.239.154; 4.O.239.157; 4.O.239.166; 4.O.239.169; 4.O.239.172; 4.O.239.175; 4.O.239.240; 4.O.239.244; 4.O.154.228; 4.O.154.229; 4.O.154.230; 4.O.154.231; 4.O.154.236; 4.O.154.237; 4.O.154.238; 4.O.154.239; 4.O.154.154; 4.O.154.157; 4.O.154.166; 4.O.154.169; 4.O.154.172; 4.O.154.175; 4.O.154.240; 4.O.154.244; 4.O.157.228; 4.O.157.229; 4.O.157.230; 4.O.157.231; 4.O.157.236; 4.O.157.237; 4.O.157.238; 4.O.157.239; 4.O.157.154; 4.O.157.157; 4.O.157.166; 4.0.157.169; 4.O.157.172; 4.O.157.175; 4.O.157.240; 4.O.157.244; 4.O.166.228; 4.O.166.229; 4.O-166.230; 4.O.166.231; 4.O.166.236; 4.O.166.237; 4.O.166.238; 4.O.166.239; 4.0.166.154; 4.O.166.157; 4.O.166.166; 4.O.166.169; 4.O.166.172; 4.O.166.175; 4.O.166.240; 4.O.166.244; 4.O.169.228; 4.O-169.229; 4.O.169.230; 4.O.169.231; 4.O.169.236; 4.O.169.237; 4.O.169.238; 4.O.169.239; 4.O.169.154; 4.O.169.157; 4.O.169.166; 4.O.169.169; 4.O.169.172; 4.O.169.175; 4.O.169.240; 4.O.169.244; 4.Q.172.228; 4.O.172.229; 4.O.172.230; 4.O.172.231; 4.O.172.236; 4.O.172.237; 4.O.172.238; 4.O.172.239; 4.O.172.154; 4.O.172.157; 4.O.172.166; 4.0.172.169; 4.O.172.172; 4.0.172.175; 4.O.172.240; 4.O.172.244; 4.O.175.228; 4.O.175.229; 4.O.175.230; 4.O.175.231; 4.O.175.236; 4.O.175.237; 4.O.175.238; 4.O.175.239; 4.0.175.154; 4.O.175.157; 4.O.175.166; 4.O.175.169; 4.O.175.172; 4.O.175.175; 4.O.175.240; 4.O.175.244; 4.O.240.228; 4.O.240.229; 4.O.240.230; 4.O.240.231; 4.O.240.236; 4.O.240.237; 4.O.240.238; 4.O.24Q.239; 4.O.240.154; 4.O.240.157; 4.O.240.166; 4.O.240.169; 4.O.240.172; 4.O.240.175; 4.O.240.240; 4.O.240.244; 4.O.244.228; 4.O.244.229; 4.O.244.230; 4.O.244.231; 4.O.244.236; 4.O.244.237; 4.O.244.238; 4.O.244.239; 4.O.244.154; 4.O.244.157; 4.O.244.166; 4.O.244.169; 4.O.244.172; 4.O.244.175; 4.O.244.240; 4.O.244.244;

Prodrugs of 4.P

4.P.228.228; 4.P.228.229; 4.P.228.230; 4.P.228.231; 4.P.228.236; 4.P.228.237; 4.P.228.238; 4.P.228.239; 4.P.228.154; 4.P.228.157; 4.P.228.166; 4.P.228.169; 4.P.228.172; 4.P.228.175; 4.P.228.240; 4.P.228.244; 4.P.229.228; 4.P.229.229; 4.P.229.230; 4.P.229.231; 4.P.229.236; 4.P.229.237; 4.P.229.238; 4.P.229.239; 4.P.229.154; 4.P.229.157; 4.P.229.166; 4.P.229.169; 4.P.229.172; 4.P.229.175; 4.P.229.240; 4.P.229.244; 4.P.230.228; 4.P.230.229; 4.P.230.230; 4.P.230.231; 4.P.230.236; 4.P.230.237; 4.P.230.238; 4.P.23Q.239; 4.P.230.154; 4.P.230.157; 4.P.230.166; 4.P.230.169; 4.P.230.172; 4.P.230.175; 4.P.230.240; 4.P.23Q.244; 4.P.231.228; 4.P.231.229; 4.P.231.23Q; 4.P.231.231; 4.P.231.236; 4.P.231.237; 4.P.231.238; 4.P.231.239; 4.P.231.154; 4.P.231.157; 4.P.231.166; 4.P.231.169; 4.P.231.172; 4.P.231.175; 4.P.231.240; 4.P.231.244; 4.P.236.228; 4.P.236.229; 4.P.236.230; 4.P.236.231; 4.P.236.236; 4.P.236.237; 4.P.236.238; 4.P.236.239; 4.P.236.154; 4.P.236.157; 4.P.236.166; 4.P.236.169; 4.P.236.172; 4.P.236.175; 4.P.236.240; 4.P.236.244; 4.P.237.228; 4.P.237.229; 4.P.237.230; 4.P.237.231; 4.P.237.236; 4.P.237.237; 4.P.237.238; 4.P.237.239; 4.P.237.154; 4.P.237.157; 4.P.237.166; 4.P.237.169; 4.P.237.172; 4.P.237.175; 4.P.237.240; 4.P.237.244; 4.P.238.228; 4.P.238.229; 4.P.238.230; 4.P.238.231; 4.P.238.236; 4.P.238.237; 4.P.238.238; 4.P.238.239; 4.P.238.154; 4.P.238.157; 4.P.238.166; 4.P.238.169; 4.P.238.172; 4.P.238.175; 4.P.238.240; 4.P.238.244; 4.P.239.228; 4.P.239.229; 4.P.239.230; 4.P.239.231; 4.P.239.236; 4.P.239.237; 4.P.239.238; 4.P.239.239; 4.P.239.154; 4.P.239.157; 4.P.239.166; 4.P.239.169; 4.P.239.172; 4.P.239.175; 4.P.239.240; 4.P.239.244; 4.P.154.228; 4.P.154.229; 4.P.154.230; 4.P.154.231; 4.P.154.236; 4.P.154.237; 4.P.154.238; 4.P.154.239; 4.P.154.154; 4.P.154.157; 4.P.154.166; 4.P.154.169; 4.P.154.172; 4.P.154.175; 4.P.154.240; 4.P.154.244; 4.P.157.228; 4.P.157.229; 4.P.157.230; 4.P.157.231; 4.P.157.236; 4.P.157.237; 4.P.157.238; 4.P.157.239; 4.P.157.154; 4.P.157.157; 4.P.157.166; 4.P.157.169; 4.P.157.172; 4.P.157.175; 4.P.157.240; 4.P.157.244; 4.P.166.228; 4.P.166.229; 4.P.166.230; 4.P.166.231; 4.P.166.236; 4.P.166.237; 4.P.166.238; 4.P.166.239; 4.P.166.154; 4.P.166.157; 4.P.166.166; 4.P.166.169; 4.P.166.172; 4.P.166.175; 4.P.166.240; 4.P.166.244; 4.P.169.228; 4.P.169.229; 4.P.169.230; 4.P.169.231; 4.P.169.236; 4.P.169.237; 4.P.169.238; 4.P.169.239; 4.P.169.154; 4.P.169.157; 4.P.169.166; 4.P.169.169; 4.P.169.172; 4.P.169.175; 4.P.169.240; 4.P.169.244; 4.P.172.228; 4.P.172.229; 4.P.172.230; 4.P.172.231; 4.P.172.236; 4.P.172.237; 4.P.172.238; 4.P.172.239; 4.P.172.154; 4.P.172.157; 4.P.172.166; 4.P.172.169; 4.P.172.172; 4.P.172.175; 4.P.172.240; 4.P.172.244; 4.P.175.228; 4.P.175.229; 4.P.175.230; 4.P.175.231; 4.P.175.236; 4.P.175.237; 4.P.175.238; 4.P.175.239; 4.P.175.154; 4.P.175.157; 4.P.175.166; 4.P.175.169; 4.P.175.172; 4.P.175.175; 4.P.175.240; 4.P.175.244; 4.P.240.228; 4.P.240.229; 4.P.240.230; 4.P.240.231; 4.P.240.236; 4.P.240.237; 4.P.240.238; 4.P.240.239; 4.P.240.154; 4.P.240.157; 4.P.240.166; 4.P.240.169; 4.P.240.172; 4.P.240.175; 4.P.240.240; 4.P.24Q.244; 4.P.244.228; 4.P.244.229; 4.P.244.230; 4.P.244.231; 4.P.244.236; 4.P.244.237; 4.P.244.238; 4.P.244.239; 4.P.244.154; 4.P.244.157; 4.P.244.166; 4.P.244.169; 4.P.244.172; 4.P.244.175; 4.P.244.240; 4.P.244.244;

Prodrugs of 4.U

4.U.228.228; 4.U.228.229; 4.U.228.230; 4.U.228.231; 4.U.228.236; 4.U.228.237; 4.U.228.238; 4.U.228.239; 4.U.228.154; 4.U.228.157; 4.U.228.166; 4.U.228.169; 4.U.228.172; 4.U.228.175; 4.U.228.240; 4.U.228.244; 4.U.229.228; 4.U.229.229; 4.U.229.230; 4.U.229.231; 4.U.229.236; 4.U.229.237; 4.U.229.238; 4.U.229.239; 4.U.229.154; 4.U.229.157; 4.U.229.166; 4.U.229.169; 4.U.229.172; 4.U.229.175; 4.U.229.240; 4.U.229.244; 4.U.230.228; 4.U.230.229; 4.U.230.230; 4.U.230.231; 4.U.230.236; 4.U.230.237; 4.U.230.238; 4.U.230.239; 4.U.230.154; 4.U.230.157; 4.U.230.166; 4.U.230.169; 4.U.230.172; 4.U.230.175; 4.U.230.240; 4.U.230.244; 4.U.231.228; 4.U.231.229; 4.U.231.230; 4.U.231.231; 4.U.231.236; 4.U.231.237; 4.U.231.238; 4.U.231.239; 4.U.231.154; 4.U.231.157; 4.U.231.166; 4.U.231.169; 4.U.231.172; 4.U.231.175; 4.U.231.240; 4.U.231.244; 4.U.236.228; 4.U.236.229; 4.U.236.230; 4.U.236.231; 4.U.236.236; 4.U.236.237; 4.U.236.238; 4.U.236.239; 4.U.236.154; 4.U.236.157; 4.U.236.166; 4.U.236.169; 4.U.236.172; 4.U.236.175; 4.U.236.240; 4.U.236.244; 4.U.237.228; 4.U.237.229; 4.U.237.230; LU 237231; 4.U.237.236; 4.U.237.237; 4.U.237.238; 4.U.237.239; 4.U.237.154; 4.U.237.157; 4.U.237.166; 4.U.237.169; 4.U.237.172; 4.U.237.175; 4.U.237.240; 4.U.237.244; 4.U.238.228; 4.U.238.229; 4.U.238.230; 4.U.238.231; 4.U.238.236; 4.U.238.237; 4.U.238.238; 4.U.238.239; 4.U.238.154; 4.U.238.157; 4.U.238.166; 4.U.238.169; 4.U.238.172; 4.U.238.175; 4.U.238.240; 4.U.238.244; 4.U.239.228; 4.U .239.229; 4.U.239.230; 4.U.239.231; 4.U.239.236; 4.U.239.237; 4.U.239.238; 4.U.239.239; 4.U.239.154; 4.U.239.157; 4.U.239.166; 4.U.239.169; 4.U.239.172; 4.U.239.175; 4.U.239.240; 4.U.239.244; 4.U.154.228; 4.U.154.229; 4.U.154.230; 4.U.154.231; 4.U.154.236; 4.U.154.237; 4.U.154.238; 4.U.154.239; 4.U.154.154; 4.U.154.157; 4.U.154.166; 4.U.154.169; 4.U.154.172; 4.U.154.175; 4.U.154.240; 4.U.154.244; 4.U.157.228; 4.U.157.229; 4.U.157.230; 4.XJ.157.231; 4.U.157.236; 4.U.157.237; 4.U.157.238; 4.U.157.239; 4.U.157.154; 4.U.157.157; 4.U.157.166; 4.U.157.169; 4.U.157.172; 4.IJ.157.175; 4.U.157.240; 4.U.157.244; 4.U.166.228; 4.U.166.229; 4.U.166.230; 4.U.166.231; 4.U.166.236; 4.U.166.237; 4.U.166.238; 4.U.166.239; 4.U.166.154; 4.U.166.157; 4.U.166.166; 4.U.166.169; 4.U.166.172; 4.U ^'.166.175; 4.U.166.240; 4.U.166.244; 4.U.169.228; 4.U.169.229; 4.U.169.230; 4.U.169.231; 4.U.169.236; 4.U.169.237; 4.U.169.238; 4.U-169.239; 4.U.169.154; 4.U.169.157; 4.U.169.166; 4.U.169.169; 4.U.169.172; 4.U.169.175; 4.U.169.240; 4.U.169.244; 4.U.172.228; 4.U.172.229; 4.U.172.230; 4.U.172.231; 4.U.172.236; 4.U.172.237; 4.U.172.238; 4.U.172.239; 4.U.172.154; 4.U.172.157; 4.U.172.166; 4.U.172.169; 4.U.172.172; 4.U.172.175; 4.U.172.240; 4.U.172.244; 4.U.175.228; 4.U.175.229; 4.U.175.230; 4.U.175.231; 4.U.175.236; 4.U.175.237; 4.U.175.238; 4.U.175.239; 4.U.175.154; 4.U.175.157; 4.U.175.166; 4.U.175.169; 4.U.175.172; 4.U.175.175; 4.U.175.240; 4.U.175.244; 4.U.240.228; 4.U.240.229; 4.U.240.230; 4.U.240.231; 4.U.240.236; 4.U.240.237; 4.U.240.238; 4.U.240.239; 4.U.240.154; 4.U.240.157; 4.U.240.166; 4.U.240.169; 4.U.240.172; 4.U.240.175; 4.U.240.240; 4.U.240.244; 4.U.244.228; 4.U.244.229; 4.U.244.230; 4.U.244.231; 4.U.244.236; 4.U.244.237; 4.U.244.238; 4.U.244.239; 4.U.244.154; 4.U.244.157; 4.U.244.166; 4.U.244.169; 4.U.244.172; 4.U.244.175; 4.U.244.240; 4.U.244.244;

Prodrugs of 4.CD

4.CD.228.228; 4.CD.228.229; 4.CD.228.230; 4.CD.228.231; 4.CD.228.236; 4.CD.228.237; 4.CD.228.238; 4.CD.228.239; 4.CD.228.154; 4.CD.228.157; 4.CD.228.166; 4.CD.228.169; 4.CD.228.172; 4.CD.228.175; 4.CD.228.240; 4.CD.228.244; 4.CD.229.228; 4.CD.229.229; 4.CD.229.230; 4.CD.229.231; 4.CD.229.236; 4.CD.229.237; 4.CD.229.238; 4.CD.229.239; 4.CD.229.154; 4.CD.229.157; 4.CD.229.166; LCD.229.169; 4.CD..229.172; 4.CD.229.175; 4.CD.229.240; 4.CD.229.244; 4.CD.230.228; 4.CD.23Q.229; 4.CD.230.230; 4.CD.230.231; 4.CD.230.236; 4.CD.230.237; 4.CD.230.238; 4.CD.230.239; 4.CD.230.154; 4.CD.230.157; 4.CD.230.166; 4.CD.23Q.169; 4.CD.230.172; 4.CD.230.175; 4.CD.230.240; 4.CD.230.244; 4.CD.231.228; 4.CD.231.229; 4.CD.231.230; 4.CD.231.231; 4.CD.231.236; 4.CD.231.237; 4.CD.231.238; 4.CD.231.239; 4.CD.231.154; 4.CD.231.157; 4.CD.231.166; 4.CD.231.169; 4.CD.231.172; 4.CD.231.175; 4.CD.231.240; 4.CD.231.244; 4.CD.236.228; 4.CD.236.229; 4.CD.236.230; 4.CD.236.231; 4.CD.236.236; 4.CD.236.237; 4.CD.236.238; 4.CD.236.239; 4.CD.236.154; 4.CD.236.157; 4.CD.236.166; 4.CD.236.169; 4.CD.236..172; 4.CD.236.175; 4.CD.236.240; 4.CD.236.244; 4.CD.237.228; 4.CD.237.229; 4.CD.237.230; 4.CD.237.231; 4.CD.237.236; 4.CD.237.237; 4.CD.237.238; 4.CD.237.239; 4.CD.237.154; 4.CD.237.157; 4.CD.237.166; 4.CD.237.169; 4.CD.237.172; 4.CD.237.175; 4.CD.237.240; 4.CD.237.244; 4.CD.238.228; 4.CD.238.229; 4.CD.238.230; 4.CD.238.231; 4.CD.238.236; 4.CD.238.237; 4.CD.238.238; 4.CD.238.239; 4.CD.238.154; 4.CD.238.157; 4.CD.238.166; 4.CD.238.169; 4.CD.238.172; 4.CD.238.175; 4.CD.238.240; 4.CD.238.244; 4.CD.239.228; 4.CD.239.229; 4.CD.239.230; 4.CD.239.231; 4.CD.239.236; 4.CD.239.237; 4.CD.239.238; 4.CD.239.239; 4.CD.239.154; 4.CD.239.157; 4.CD.239.166; 4.CD.239.169; 4.CD.239.172; 4.CD.239.175; 4.CD.239.240; 4.CD.239.244; 4.CD.154.228; 4.CD.154.229; 4.CD.154.230; 4.CD.154.231; 4.CD.154.236; 4.CD.154.237; 4.CD.154.238; 4.CD.154.239; 4.CD.154.154; 4.CD.154.157; 4.CD.154.166; 4.CD.154.169; 4.CD.154.172; 4.CD.154.175; 4.CD.154.240; 4.CD.154.244; 4.CD.157.228; 4.CD.157.229; 4.CD.157.230; 4.CD.157.231; 4.CD.157.236; 4.CD.157.237; 4.CD.157.238; 4.CD.157.239; 4.CD.157.154; 4.CD.157.157; 4.CD.157.166; 4.CD.157.169; 4.CD.157.172; 4.CD.157.175; 4.CD.157.240; 4.CD.157.244; 4.CD.166.228; 4.CD.166.229; 4.CD.166.230; 4.CD.166.231; 4.CD.166.236; 4.CD.166.237; 4.CD.166.238; 4.CD.166.239; 4.CD.166.154; 4.CD.166.157; 4.CD.166.166; 4.CU166.169; 4.CD.166.172; 4.CD.166.175; 4.CD.166.24Q; 4.CD.166.244; 4.CD.169.228; 4.CD.169.229; 4.CD.169.230; 4.CD.169.231; 4.CD.169.236; 4.CD.169.237; 4.CD.169.238; 4.CD.169.239; 4.CD.169.154; 4.CD.169.157; 4.CD.169.166; 4.CD.169.169; 4.CD.169.172; 4.CD.169.175; 4.CD.169.240; 4.CD.169.244; 4.CD.172.228; 4.CD.172.229; 4.CD.172.230; 4.CD.172.231; 4.CD.172.236; 4.CD.172.237; 4.CD.172.238; 4.CD.172.239; 4.CD.172.154; 4.CD.172.157; 4.CD.172.166; 4.CD.172.169; 4.CD.172.172; 4.CD.172.175; 4.CD.172.240; 4.CD.172.244; 4.CD.175.228; 4.CD.175.229; 4.CD.175.230; 4.CD.175.231; 4.CD.175.236; 4.CD.175.237; 4.CD.175.238; 4.CD.175.239; 4.CD.175.154; 4.CD.175.157; 4.CD.175.166; 4.CD.175.169; 4.CD.175.172; 4.CD.175.175; 4.CD.175.240; 4.CD.175.244; 4.CD.240.228; 4.CD.240.229; 4.CD.240.230; 4.CD.240.231; 4.CD.240.236; 4.CD.240.237; 4.CD.240.238; 4.CD.240.239; 4.CD.240.154; 4.CD.240.157; 4.CD.240.166; 4.CD.240.169; 4.CD.240.172; 4.CD.240.175; 4.CD.240.240; 4.CD.24Q.244; 4.CD.244.228; 4.CD.244.229; 4.CD.244.230; 4.CD.244.231; 4.CD.244.236; 4.CD.244.237; 4.CD.244.238; 4.CD.244.239; 4.CD.244.154; 4.CD.244.157; 4.CD.244.166; 4.CD.244.169; 4.CD.244.172; 4.CD.244.175; 4.CD.244.240; 4.CD.244.244;

Prodrugs of 4.EB

4.EB.228.228; 4.EB.228.229; 4.EB.228.230; 4.EB.228.231; 4.EB.228.236; 4.EB.228.237; 4.EB.228.238; 4.EB.228.239; 4.EB.228.154; 4.EB.228.157; 4.EB.228.166; 4.EB.228.169; 4.EB.228.172; 4.EB.228.175; 4.EB.228.240; 4.EB.228.244; 4.EB.229.228; 4.EB.229.229; 4.EB.229.230; 4.EB.229.231; 4.EB.229.236; A.ΕB.229.237; 4.EB.229.238; 4.EB.229.239; 4.EB.229.154; 4.EB.229.157; 4.EB.229.166; 4.EB.229.169; 4.EB.229.172; 4.EB.229.175; 4.EB.229.240; 4.EB.229.244; 4.EB.230.228; 4.EB.230.229; 4.EB.230.230; 4.EB.230.231; 4.EB.230.236; 4.EB.230.237; 4.EB.230.238; 4.EB.230.239; 4.EB.230.154; 4.EB.230.157; 4.EB.230.166; 4.EB.230.169; 4.EB.230.172; 4.EB.230.175; 4.EB.230.240; 4.EB.230.244; 4.EB.231.228; 4.EB.231.229; 4.EB.231.230; 4.EB.231.231; 4.EB.231.236; 4.EB.231.237; 4.EB.231.238; 4.EB.231.239; 4.EB.231.154; 4.EB.231.157; 4.EB.231.166; 4.EB.231.169; 4.EB.231.172; 4.EB.231.175; 4.EB.231.240; 4.EB.231.244; 4.EB.236.228; 4.EB.236.229; 4.EB.236.230; 4.EB.236.231; 4.EB.236.236; 4.EB.236.237; 4.EB.236.238; 4.EB.236.239; 4.EB.236.154; 4.EB.236.157; 4.EB.236.166; 4.EB.236.169; 4.EB.236.172; 4.EB.236.175; 4.EB.236.240; 4.EB.236.244; 4.EB.237.228; 4.EB.237.229; 4.EB.237.230; 4.EB.237.231; 4.EB.237.236; 4.EB.237.237; 4.EB.237.238; 4.EB.237.239; 4.EB.237.154; 4.EB.237.157; 4.EB.237.166; 4.EB.237.169; 4.EB.237.172; 4.EB.237.175; 4.EB.237.240; 4.EB.237.244; 4.EB.238.228; 4.EB.238.229; 4.EB.238.230; 4.EB.238.231; 4.EB.238.236; 4.EB.238.237; 4.EB.238.238; 4.EB.238.239; 4.EB.238.154; 4.EB.238.157; 4.EB.238.166; 4.EB.238.169; 4.EB.238.172; 4.EB.238.175; 4.EB.238.24Q; 4.EB.238.244; 4.EB.239.228; 4.EB.239.229; 4.EB.239.230; 4.EB.239.231; 4.EB.239.236; 4.EB.239.237; 4.EB.239.238; 4.EB.239.239; 4.EB.239.154; 4.EB.239.157; 4.EB.239.166; 4.EB.239.169; 4.EB.239.172; 4.EB.239.175; 4.EB.239.240; 4.EB.239.244; 4.EB.154.228; 4.EB.154.229; 4.EB.154.230; 4.EB.154.231; 4.EB.154.236; 4.EB.154.237; 4.EB.154.238; 4.EB.154.239; 4.EB.154.154; 4.EB.154.157; 4.EB.154.166; 4.EB.154.169; 4.EB.154.172; 4.EB.154.175; 4.EB.154.240; 4.EB.154.244; 4.EB.157.228; 4.EB.157.229; 4.EB.157.230; 4.EB.157.231; 4.EB.157.236; 4.EB.157.237; 4.EB.157.238; 4.EB.157.239; 4.EB.157.154; 4.EB.157.157; 4.EB.157.166; 4.EB.157.169; 4.EB.157.172; 4.EB.157.175; 4.EB.157.240; 4.EB.157.244; 4.EB.166.228; 4.EB.166.229; 4.EB.166.230; 4.EB.166.231; 4.EB.166.236; 4.EB.166.237; 4.EB.166.238; 4.EB.166.239; 4.EB.166.154; 4.EB.166.157; 4.EB.166.166; 4.EB.166.169; 4.EB.166.172; 4.EB.166.175; 4.EB.166.240; 4.EB.166.244; 4.EB.169.228; 4.EB.169.229; 4.EB.169.230; 4.EB.169.231; 4.EB.169.236; 4.EB.169.237; 4.EB.169.238; 4.EB.169.239; 4.EB.169.154; 4.EB.169.157; 4.EB.169.166; 4.EB.169.169; 4.EB.169.172; 4.EB.169.175; 4.EB.169.240; 4.EB.169.244; 4.EB-172.228; 4.EB.172.229; 4.EB.172.230; 4.EB.172.231; 4.EB.172.236; 4.EB.172.237; 4.EB.172.238; 4.EB.172.239; 4.EB.172.154; 4.EB.172.157; 4.EB.172.166; 4.EB.172.169; 4.EB.172.172; 4.EB.172.175; 4.EB.172.240; 4.EB.172.244; 4.EB.175.228; 4.EB.175.229; 4.EB.175.230; 4.EB.175.231; 4.EB.175.236; 4.EB.175.237; 4.EB.175.238; 4.EB.175.239; 4.EB.175.154; 4.EB.175.157; 4.EB.175.166; 4.EB.175.169; 4.EB.175.172; 4.EB.175.175; 4.EB.175.240; 4.EB.175.244; 4.EB.240.228; 4.EB.240.229; 4.EB.240.230; 4.EB.240.231; 4.EB.240.236; 4.EB.24Q.237; 4.EB.240.238; 4.EB.240.239; 4.EB.240.154; 4.EB.240.157; 4.EB.240.166; 4.EB.24Q.169; 4.EB.240.172; 4.EB.240.175; 4.EB.240.240; 4.EB.240.244; 4.EB.244.228; 4.EB.244.229; 4.EB.244.230; 4.EB.244.231; 4.EB.244.236; 4.EB.244.237; 4.EB.244.238; 4.EB.244.239; 4.EB.244.154; 4.EB.244.157; 4.EB.244.166; 4.EB.244.169; 4.EB.244.172; 4.EB.244.175; 4.EB.244.240; 4.EB.244.244;

Prodrugs of 5.B

5.B.228.228; 5.B.228.229; 5.B.228.230; 5.B.228.231; 5.B.228.236; 5.B.228.237; 5.B.228.238; 5.B.228.239; 5.B.228.154; 5.B.228.157; 5.B.228.166; 5-B.228.169; 5.B.228.172; 5.B.228.175; 5.B.228.240; 5.B.228.244; 5.B.229.228; 5.B.229.229; 5.B.229.230; 5.B.229.231; 5.B.229.236; 5.B.229.237; 5.B.229.238; 5.B.229.239; 5.B.229.154; 5.B.229.157; 5.B.229.166; 5.B.229.169; 5.B.229.172; 5.B.229.175; 5.B.229.240; 5.B.229.244; 5.B.230.228; 5.B.230.229; 5.B.230.230; 5.B.230.231; 5.B.230.236; 5.B.230.237; 5.B.230.238; 5.B.230.239; 5.B.230.154; 5.B.230.157; 5.B.230.166; 5.B.230.169; 5.B.230.172; 5.B.230.175; 5.B.230.240; 5.B.230.244; 5.B.231.228; 5.B.231.229; 5.B.231.230; 5.B.231.231; 5.B.231.236; 5.B.231.237; 5.B.231.238; 5.B.231.239; 5.B.231.154; 5.B.231.157; 5.B.231.166; 5.B.231.169; 5.B.231.172; 5.B.231.175; 5.B.231.240; 5.B.231.244; 5.B.236.228; 5.B.236.229; 5.B.236.230; 5.B.236.231; 5.B.236.236; 5.B.236.237; 5.B.236.238; 5.B.236.239; 5.B.236.154; 5.B.236.157; 5.B.236.166; 5.B.236.169; 5.B.236.172; 5.B.236.175; 5.B.236.240; 5.B.236.244; 5.B.237.228; 5.B.237.229; 5.B.237.230; 5.B.237.231; 5.B.237.236; 5.B.237.237; 5.B.237.238; 5.B.237.239; 5.B.237.154; 5.B.237.157; 5.B.237.166; 5.B.237.169; 5.B.237.172; 5.B.237.175; 5.B.237.240; 5.B.237.244; 5.B.238.228; 5.B.238.229; 5.B.238.230; 5.B.238.231; 5.B.238.236; 5.B.238.237; 5.B.238.238; 5.B.238.239; 5.B.238.154; 5.B.238.157; 5.B.238.166; 5.B.238.169; 5.B.238.172; 5.B.238.175; 5.B.238.24Q; 5.B.238.244; 5.B.239.228; 5.B.239.229; 5.B.239.230; 5.B.239.231; 5.B.239.236; 5.B.239.237; 5.B.239.238; 5.B.239.239; 5.B.239.154; 5.B.239.157; 5.B.239.166; 5.B.239.169; 5.B.239.172; 5.B.239.175; 5.B.239.240; 5.B.239.244; 5.B.154.228; 5.B.154.229; 5.B.154.230; 5.B.154.231; 5.B.154.236; 5.B.154.237; 5.B.154.238; 5.B.154.239; 5.B.154.154; 5.B.154.157; 5.B.154.166; 5.B.154.169; 5.B.154.172; 5.B.154.175; 5.B.154.240; 5.B.154.244; 5.B.157.228; 5.B.157.229; 5.B.157.230; 5.B.157.231; 5.B.157.236; 5.B.157.237; 5.B.157.238; 53.157.239; 5.B.157.154; 5.B.157.157; 5.B.157.166; 5.B.157.169; 5.B.157.172; 5.B.157.175; 5.B.157.240; 5.B.157.244; 5.B.166.228; 5.B.166.229; 5.B.166.230; 5.B.166.231; 5.B.166.236; 5.B.166.237; 5.B.166.238; 5.B.166.239; 5.B.166.154; 5.B.166.157; 5.B.166.166; 5.B.166.169; 5.B.166.172; 5.B.166.175; 5.B.166.240; 5.B.166.244; 5.B.169.228; 5.B.169.229; 5.B.169.230; 5.B.169.231; 5.B.169.236; 5.B.169.237; 5.B.169.238; 5.B.169.239; 5.B.169.154; 5.B.169.157; 5.B.169.166; 5.B.169.169; 5.B.169.172; 5.B.169.175; 5.B.169.240; 5.B.169.244; 5.B.172.228; 5.B.172.229; 5.B.172.230; 5.B.172.231; 5.B.172.236; 5.B.172.237; 5.B.172.238; 5.B.172.239; 5.B.172.154; 5.B.172.157; 5.B.172.166; 5.B.172.169; 5.B.172.172; 5.B.172.175; 5.B.172.24Q; 5.B.172.244; 5.B.175.228; 5.B.175.229; 5.B.175.230; 5.B.175.231; 5.B.175.236; 5.B.175.237; 5.B.175.238; 5.B.175.239; 5.B.175.154; 5.B.175.157; 5.B.175.166; 5.B.175.169; 5.B.175.172; 5.B.175.175; 5.B.175.240; 5.B.175.244; 5.B.240.228; 5.B.240.229; 5.B.240.230; 5.B.240.231; 5.B.240.236; 5.B.240.237; 5.B.240.238; 5.B.240.239; 5.B.240.154; 5.B.240.157; 5.B.240.166; 5.B.240.169; 5.B.240.172; 5.B.240.175; 5.B.240.240; 5.B.240.244; 5.B.244.228; 5.B.244.229; 5.B.244.230; 5.B.244.231; 5.B.244.236; 5.B.244.237; 5.B.244.238; 5.B.244.239; 5.B.244.154; 5.B.244.157; 5.B.244.166; 5.B.244.169; 5.B.244.172; 5.B.244.175; 5.B.244.24Q; 5.B.244.244;

Prodrugs of 5.D

5.D.228.228; 5.D.228.229; 5.D.228-230; 5.D.228.231; 5.D.228.236; 5.D.228.237; 5.D.228.238; 5.D.228.239; 5.U228.154; 5.D.228.157; 5.D.228.166; 5.D.228.169; 5.D.228.172; 5.D.228.175; 5.D.228.240; 5.D.228.244; 5.D.229.228; 5.D.229.229; 5.D.229.230; 5.D.229.231; 5.D.229.236; 5.D.229.237; 5.D.229.238; 5.D.229.239; 5.D.229.154; 5.D.229.157; 5.D.229.166; 5.D.229.169; 5.D.229.172; 5.D.229.175; 5.D.229.240; 5.D.229.244; 5.D.23Q.228; 5.P.230.229; 5.D.230.230; 5.D.230.231; 5.D.230.236; 5.D.230.237; 5.D.230.238; 5.D.230.239; 5.D.230.154; 5.D.230.157; 5.D.230.166; 5.D.230.169; 5.D.230.172; 5.D.230.175; 5.D.230.240; 5.D.230.244; 5.D.231.228; 5.D.231.229; 5.D.231.230; 5.D.231.231; 5.D.231.236; 5.D.231.237; 5.D.231.238; 5.D.231.239; 5.D.231.154; 5.D.231.157; 5.D.231.166; 5.D.231.169; 5.D.231.172; 5.D.231.175; 5.D.231.240; 5.D.231.244; 5.D.236.228; 5.D.236.229; 5.D.236.230; 5.D.236.231; 5.D.236.236; 5.D.236.237; 5.D.236.238; 5.D.236.239; 5.D.236.154; 5.D.236.157; 5.D.236.166; 5.D.236.169; 5.D.236.172; 5.D.236.175; 5.D.236.240; 5.D.236.244; 5.D.237.228; 5.D.237.229; 5.D.237.230; 5.D.237.231; 5.D.237.236; 5.D.237.237; 5.D.237.238; 5.D.237.239; 5.D.237.154; 5.D.237.157; 5.D.237.166; 5.D.237.169; 5.D.237.172; 5.D.237.175; 5.D.237.240; 5.D.237.244; 5.D.238.228; 5.D.238.229; 5.D.238.230; 5.D.238.231; 5.D.238.236; 5.D.238.237; 5.D.238.238; 5.D.238.239; 5-D.238.154; 5.D.238.157; 5.D.238.166; 5.D.238.169; 5.D.238.172; 5.D.238.175; 5.D.238.240; 5.D.238.244; 5.D.239.228; 5.D.239.229; 5.D.239.230; 5.D.239.231; 5.D.239.236; 5.D.239.237; 5.D.239.238; 5.D.239.239; 5.D.239.154; 5.D.239.157; 5.D.239.166; 5.D.239.169; 5.D.239.172; 5.D.239.175; 5.D.239.240; 5.D.239.244; 5.D.154.228; 5.D.154.229; 5.D.154.230; 5.D.154.231; 5.D.154.236; 5.D.154.237; 5.D.154.238; 5.D.154.239; 5.D.154.154; 5.D.154.157; 5.D.154.166; 5.D.154.169; 5.D.154.172; 5.D.154.175; 5.D.154.240; 5.D.154.244; 5.D.157.228; 5.D.157.229; 5.D.157.230; 5.D.157.231; 5.D.157.236; 5.D.157.237; 5.D.157.238; 5.D.157.239; 5.D.157.154; 5.P.157.157; 5.D.157.166; 5.D.157.169; 5.D.157.172; 5.D.157.175; 5.D.157.240; 5.D.157.244; 5.D.166.228; 5.D.166.229; 5.D.166.230; 5.D.166.231; 5.D.166.236; 5.D.166.237; 5.D.166.238; 5.D.166.239; 5.D.166.154; 5.D.166.157; 5.D.166.166; 5.D.166.169; 5.D.166.172; 5.D.166.175; 5.D.166.240; 5.D.166.244; 5.D.169.228; 5.D.169.229; 5.D.169.230; 5.D.169.231; 5.D.169.236; 5.D.169.237; 5.D.169.238; 5.D.169.239; 5.D.169.154; 5.D.169.157; 5.D.169.166; 5.D.169.169; 5.D.169.172; 5.D.169.175; 5.D.169.240; 5.D.169.244; 5.D.172.228; 5.D.172.229; 5.D.172.230; 5.D.172.231; 5.D.172.236; 5.D.172.237; 5.D.172.238; 5.D.172.239; 5.D.172.154; 5.D.172.157; 5.D.172.166; 5.D.172.169; 5.D.172.172; 5.D.172.175; 5.D.172.240; 5.D.172.244; 5.D.175.228; 5.D.175.229; 5.D.175.230; 5.D.175.231; 5.D.175.236; 5.D.175.237; 5.D.175.238; 5.D.175.239; 5.D.175.154; 5.D.175.157; 5.D.175.166; 5.D.175.169; 5.D.175.172; 5.D.175.175; 5.D.175.240; 5.D.175.244; 5.D.240.228; 5.D.240-229; 5.D.240.230; 5.D.240.231; 5.D.240.236; 5.D.240.237; 5.D.240.238; 5.D.240.239; 5.D.240.154; 5.D.240.157; 5.D.240.166; 5.D.24Q.169; 5.D.240.172; 5.D.240.175; 5.D.240.240; 5.D.240.244; 5.D.244.228; 5.D.244.229; 5.D.244.230; 5.D.244.231; 5.D.244.236; 5.D.244.237; 5.D.244.238; 5.D.244.239; 5.D.244.154; 5.D.244.157; 5.D.244.166; 5.D.244.169; 5.D.244.172; 5.D.244.175; 5.D.244.240; 5.D.244.244;

Prodrugs of 5.AB

5.AB.228.228; 5.AB.228.229; 5.AB.228.230; 5.AB.228.231; 5.AB.228.236; 5.AB.228.237; 5.AB.228.238; 5.AB.228.239; 5.AB.228.154; 5.AB.228.157; 5.AB.228.166; 5.AB.228.169; 5.AB.228.172; 5.AB.228.175; 5.AB.228.240; 5.AB.228.244; 5.AB.229.228; 5.AB.229.229; 5.AB.229.230; 5.AB.229.231; 5.AB.229.236; 5.AB.229.237; 5.AB.229.238; 5.AB.229.239; 5.AB.229.154; 5.AB.229.157; 5.AB.229.166; 5.AB.229.169; 5.AB.229.172; 5.AB.229.175; 5.AB.229.240; 5.AB.229.244; 5.AB.230.228; 5.AB.230.229; 5.AB.230.230; 5.AB.230.231; 5.AB.230.236; 5.AB.230.237; 5.AB.230.238; 5.AB.230.239; 5.AB.230.154; 5.AB.230.157; 5.AB.230.166; 5.AB.230.169; 5.AB.230.172; 5.AB.230.175; 5.AB.230.240; 5.AB.230.244; 5.AB.231.228; 5.AB.231.229; 5.AB.231.230; 5.AB.231.231; 5.AB.231.236; 5.AB.231.237; 5.AB.231.238; 5.AB.231.239; 5.AB.231.154; 5.AB.231.157; 5.AB.231.166; 5.AB.231.169; 5.AB.231.172; 5.AB.231.175; 5.AB.231.240; 5.AB.231.244; 5.AB.236.228; 5.AB.236.229; 5.AB.236.230; 5.AB.236.231; 5.AB.236.236; 5.AB.236.237; 5.AB.236.238; 5.AB.236.239; 5.AB.236.154; 5.AB.236.157; 5.AB.236.166; 5.AB.236.169; 5.AB.236.172; 5.AB.236.175; 5.AB.236.240; 5.AB.236.244; 5.AB.237.228; 5.AB.237.229; 5.AB.237.230; 5.AB.237.231; 5.AB.237.236; 5.AB.237.237; 5.AB.237.238; 5.AB.237.239; 5.AB.237.154; 5.AB.237.157; 5.AB.237.166; 5.AB.237.169; 5.AB.237.172; 5.AB.237.175; 5.AB.237.240; 5.AB.237.244; 5.AB.238.228; 5.AB.238.229; 5.AB.238.230; 5.AB.238.231; 5.AB.238.236; 5.AB.238.237; 5.AB.238.238; 5.AB.238.239; 5.AB.238.154; 5.AB.238.157; 5.AB.238.166; 5.AB.238.169; 5.AB.238.172; 5.AB.238.175; 5.AB.238.240; 5.AB.238.244; 5.AB.239.228; 5.AB.239.229; 5.AB.239.230; 5.AB.239.231; 5.AB.239.236; 5.AB.239.237; 5.AB.239.238; 5.AB.239.239; 5.AB.239.154; 5.AB.239.157; 5.AB.239.166; 5.AB.239.169; 5.AB.239.172; 5.AB.239.175; 5.AB.239.240; 5.AB.239.244; 5.AB.154.228; 5.AB.154.229; 5.AB.154.230; 5.AB.154.231; 5.AB.154.236; 5.AB.154.237; 5.AB.154.238; 5.AB.154.239; 5.AB.154.154; 5.AB.154.157; 5.AB.154.166; 5.AB.154.169; 5.AB.154.172; 5.AB.154.175; 5.AB.154.240; 5.AB.154.244; 5.AB.157.228; 5.AB.157.229; 5.AB.157.230; 5.AB.157.231; 5.AB.157.236; 5.AB.157.237; 5.AB.157.238; 5.AB.157.239; 5.AB.157.154; 5.AB.157.157; 5. AB.157.166; 5.AB.157.169; 5.AB.157.172; 5.AB.157.175; 5.AB.157.240; 5.AB.157.244; 5.AB.166.228; 5.AB.166.229; 5.AB.166.230; 5.AB.166.231; 5.AB.166.236; 5.AB.166.237; 5.AB.166.238; 5.AB.166.239; 5.AB.166.154; 5.AB.166.157; 5.AB.166.166; 5.AB.166.169; 5.AB.166.172; 5.AB.166.175; 5.AB.166.240; 5.AB.166.244; 5.AB.169.228; 5.AB.169.229; 5.AB.169.230; 5.AB.169.231; 5.AB.169.236; 5.AB.169.237; 5.AB.169.238; 5.AB.169.239; 5.AB.169.154; 5.AB.169.157; 5.AB.169.166; 5.AB.169.169; 5.AB.169.172; 5.AB.169.175; 5.AB.169.240; 5.AB.169.244; 5.AB.172.228; 5.AB.172.229; 5.AB.172.230; 5.AB.172.231; 5.AB.172.236; 5.AB.172.237; 5.AB.172.238; 5.AB.172.239; 5.AB.172.154; 5.AB.172.157; 5.AB.172.166; 5.AB.172.169; 5.AB.172.172; 5.AB.172.175; 5.AB.172.240; 5.AB.172.244; 5.AB.175.228; 5.AB.175.229; 5.AB.175.230; 5.AB.175.231; 5.AB.175.236; 5.AB.175.237; 5.AB.175.238; 5.AB.175.239; 5.AB.175.154; 5.AB.175.157; 5.AB.175.166; 5.AB.175.169; 5.AB.175.172; 5.AB.175.175; 5.AB.175.240; 5.AB.175.244; 5.AB.240.228; 5.AB.240.229; 5.AB.240.230; 5.AB.240.231; 5.AB.240.236; 5.AB.240.237; 5.AB.240.238; 5.AB.24Q.239; 5.AB.240.154; 5.AB.240.157; 5.AB.240.166; 5.AB.240.169; 5.AB.240.172; 5.AB.240.175; 5.AB.240.240; 5.AB.240.244; 5.AB.244.228; 5.AB.244.229; 5.AB.244.230; 5.AB.244.231; 5.AB.244.236; 5.AB.244.237; 5.AB.244.238; 5.AB.244.239; 5.AB.244.154; 5.AB.244.157; 5.AB.244.166; 5.AB.244.169; 5.AB.244.172; 5.AB.244.175; 5.AB.244.240; 5.AB.244.244;

Prodrugs of 5.BI

5.BI.228.228; 5.BI.228.229; 5.BI.228.230; 5.BI.228.231; 5.BI.228.236; 5.BI.228.237; 5.BI.228.238; 5.BI.228.239; 5.BI.228.154; 5.BI.228.157; 5.BI.228.166; 5.BI.228.169; 5.BI.228.172; 5.BI.228.175; 5.BI.228.240; 5.BI.228.244; 5.BI.229.228; 5.BI.229.229; 5.BI.229.230; 5.BI.229.231; 5.BI.229.236; 5.BI.229.237; 5.BI.229.238; 5.BI.229.239; 5.BI.229.154; 5.BI.229.157; 5.BI.229.166; 5.BI.229.169; 5.BI.229.172; 5.BI.229.175; 5.BI.229.240; 5.BI.229.244; 5.BI.230.228; 5.BI.230.229; 5.BI.230.230; 5.BI.230.231; 5.BI.230.236; 5.BI.230.237; 5.BI.230.238; 5.BI.230.239; 5.BI.230.154; 5.BI.230.157; 5.BI.230.166; 5.BI.230.169; 5.BI.230.172; 5.BI.230.175; 5.BL230.240; 5.BI.230.244; 5.BI.231.228; 5.BI.231.229; 5.BI.231.230; 5.BI.231.231; 5.BI.231.236; 5.BI.231.237; 5.BI.231.238; 5.BI.231.239; 5.BI.231.154; 5.BI.231.157; 5.BI.231.166; 5.BI.231.169; 5.BI.231.172; 5.BI.231.175; 5.BI.231.240; 5.BI.231.244; 5.BI.236.228; 5.BI.236.229; 5.BI.236.230; 5.BI.236.231; 5.BI.236.236; 5.BI.236.237; 5.BL236.238; 5.BI.236.239; 5.BI.236.154; 5.BI.236.157; 5.BI.236.166; 5.BI.236.169; 5.BI.236.172; 5.BI.236.175; 5.BI.236.240; 5.BI.236.244; 5.BI.237.228; 5.BI.237.229; 5.BI.237.230; 5.BI.237.231; 5.BI.237.236; 5.BI.237.237; 5.BI.237.238; 5.BI.237.239; 5.BI.237.154; 5.BI.237.157; 5.BI.237.166; 5.BI.237.169; 5.BI.237.172; 5.BI.237.175; 5.BI.237.240; 5.BI.237.244; 5.BI.238.228; 5.BI.238.229; 5.BI.238.230; 5.BI.238.231; 5.BI.238.236; 5.BI.238.237; 5.BI.238.238; 5.BI.238.239; 5.BI.238.154; 5.BI.238.157; 5.BI.238.166; 5.BI.238.169; 5.BL238.172; 5.BL238.175; 5.BI.238.240; 5.BI.238.244; 5.BI.239.228; 5.BI.239.229; 5.BI.239.230; 5.BI.239.231; 5.BI.239.236; 5.BL239.237; 5.BI.239.238; 5.BI.239.239; 5.BI.239.154; 5.BI.239.157; 5.BI.239.166; 5.BI.239.169; 5.BL239.172; 5.BI.239.175; 5.BI.239.240; 5.BI.239.244; 5.BI.154.228; 5.BI.154.229; 5.BI.154.230; 5.BI.154.231; 5.BI.154.236; 5.BI.154.237; 5.BI.154.238; 5.BI.154.239; 5.BI.154.154; 5.BI.154.157; 5.BI.154.166; 5.BI.154.169; 5.BI.154.172; 5.BI.154.175; 5.BI.154.240; 5.BI.154.244; 5.BI.157.228; 5.BI.157.229; 5.BI.157.230; 5.BI.157.231; 5.BL157.236; 5.BI.157.237; 5.BI.157.238; 5.BI.157.239; 5.BI.157.154; 5.BI.157.157; 5.BI.157.166; 5.BI.157.169; 5.BI.157.172; 5.BI.157.175; 5.BI.157.240; 5.BI.157.244; 5.BI.166.228; 5.BI.166.229; 5.BI.166.230; 5.BI.166.231; 5.BI.166.236; 5.BI.166.237; 5.BI.166.238; 5.BI.166.239; 5.BI.166.154; 5.BI.166.157; 5.BI.166.166; 5.BI.166.169; 5.BI.166.172; 5.BI.166.175; 5.BI.166.240; 5.BI.166.244; 5.BI.169.228; 5.BI.169.229; 5.BI.169.230; 5.BI.169.231; 5.BI.169.236; 5.BI.169.237; 5.BI.169.238; 5.BI.169.239; 5.BI.169.154; 5.BI.169.157; 5.BI.169.166; 5.BI.169.169; 5.BI.169.172; 5.BI.169.175; 5.BI.169.240; 5.BI.169.244; 5.BI.172.228; 5.BI.172.229; 5.BI.172.230; 5.BI.172.231; 5.BI.172.236; 5.BI.172.237; 5.BI.172.238; 5.BI.172.239; 5.BI.172.154; 5.BI.172.157; 5.BI.172.166; 5.BI.172.169; 5.BI.172.172; 5.BI.172.175; 5.BI.172.240; 5.BI.172.244; 5.BI.175.228; 5.BI.175.229; 5.BI.175.230; 5.BI.175.231; 5.BI.175.236; 5.BI.175.237; 5.BI.175.238; 5.BI.175.239; 5.BI.175.154; 5.BI.175.157; 5.BI.175.166; 5.BI.175.169; 5.BI.175.172; 5.BI.175.175; 5.BI.175.240; 5.BI.175.244; 5.BI.240.228; 5.BI.240.229; 5.BI.240.230; 5.BI.240.231; 5.BI.240.236; 5.BI.240.237; 5.BI.24Q.238; 5.BI.240.239; 5.BI.240.154; 5.BI.240.157; 5.BI.240.166; 5.BI.240.169; 5.BI.240.172; 5.BI.240.175; 5.BI.240.240; 5.BI.240.244; 5.BI.244.228; 5.BI.244.229; 5.BI.244.230; 5.BI.244.231; 5.BI.244.236; 5.BI.244.237; 5.BI.244.238; 5.BI.244.239; 5.BI.244.154; 5.BL244.157; 5.BI.244.166; 5.BI.244.169; 5.BI.244.172; 5.BI.244.175; 5.BI.244.240; 5.BI.244.244;

Prodrugs of 5.1

5.1.228.228; 5.1.228.229; 5.1.228.230; 5.1.228.231; 5.1.228.236; 5.1.228.237; 5.1.228.238; 5.1.228.239; 5.1.228.154; 5.1.228.157; 5.1.228.166; 5.1.228.169; 5.1.228.172; 5.1.228.175; 5.1.228.240; 5.1.228.244; 5.1.229.228; 5.1.229.229; 5.1.229.230; 5.1.229.231; 5.1.229.236; 5.1.229.237; 5.1.229.238; 5.1.229.239; 5.1.229.154; 5.1.229.157; 5.1.229.166; 5.1.229.169; 5.1.229.172; 5.1.229.175; 5.1.229.240; 5.1.229.244; 5.1.230.228; 5.1.230.229; 5.1.230.230; 5.1.230.231; 5.1.230.236; 5.1.230.237; 5.1.230.238; 5.1.230.239; 5.1.230.154; 5.1.230.157; 5.1.230.166; 5.1.230.169; 5.1.230.172; 5.1.230.175; 5.1.230.240; 5.1.230.244; 5.1.231.228; 5.1.231.229; 5.1.231.230; 5.1.231.231; 5.1.231.236; 5.1.231.237; 5.1.231.238; 5.1.231.239; 5.1.231.154; 5.1.231.157; 5.1.231.166; 5.1.231.169; 5.1.231.172; 5.1.231.175; 5.1.231.240; 5.1.231.244; 5.1.236.228; 5.1.236.229; 5.1.236.230; 5.1.236.231; 5.1.236.236; 5.1.236.237; 5.1.236.238; 5.1.236.239; 5.1.236.154; 5.1.236.157; 5.1.236.166; 5.1.236.169; 5.1.236.172; 5.1.236.175; 5.1.236.240; 5.1.236.244; 5.1.237.228; 5.1.237.229; 5.1.237.230; 5.1.237.231; 5.1.237.236; 5.1.237.237; 5.1.237.238; 5.1.237.239; 5.1.237.154; 5.1.237.157; 5.1.237.166; 5.1.237.169; 5.1.237.172; 5.1.237.175; 5.1.237.240; 5.1.237.244; 5.1.238.228; 5.1.238.229; 5.1.238.230; 5.1.238.231; 5.1.238.236; 5.1.238.237; 5.1.238.238; 5.1.238.239; 5.1.238.154; 5.1.238.157; 5.1.238.166; 5.1.238.169; 5.1.238.172; 5.1.238.175; 5.1.238.240; 5.1.238.244; 5.1.239.228; 5.1.239.229; 5.1.239.230; 5.1.239.231; 5.1.239.236; 5.1.239.237; 5.1.239.238; 5.1.239.239; 5.1.239.154; 5.1.239.157; 5.1.239.166; 5.1.239.169; 5.1.239.172; 5.1.239.175; 5.1.239.240; 5.1.239.244; 5.1.154.228; 5.1.154.229; 5.1.154.230; 5.1.154.231; 5.1.154.236; 5.1.154.237; 5.1.154.238; 5.1.154.239; 5.1.154.154; 5.1.154.157; 5.1.154.166; 5.1.154.169; 5.1.154.172; 5.1.154.175; 5.1.154.240; 5.1.154.244; 5.1.157.228; 5.1.157.229; 5.1.157.230; 5.1.157.231; 5.1.157.236; 5.1.157.237; 5.1.157.238; 5.1.157.239; 5.1.157.154; 5.1.157.157; 5.1.157.166; 5.1.157.169; 5.1.157.172; 5.1.157.175; 5.1.157.240; 5.1.157.244; 5.1.166.228; 5.1.166.229; 5.1.166.230; 5.1.166.231; 5.1.166.236; 5.1.166.237; 5.1.166.238; 5.1.166.239; 5.1.166.154; 5.1.166.157; 5.1.166.166; 5.1.166.169; 5.1.166.172; 5.1.166.175; 5.1.166.240; 5.1.166.244; 5.1.169.228; 5.1.169.229; 5-1.169.230; 5.1.169.231; 5.1.169.236; 5.1.169.237; 5.1.169.238; 5.1.169.239; 5.1.169.154; 5.1.169.157; 5.1.169.166; 5.1.169.169; 5.1.169.172; 5.1.169.175; 5.1.169.240; 5.1.169.244; 5.1.172.228; 5.1.172.229; 5.1.172.230; 5.1.172.231; 5.1.172.236; 5.1.172.237; 5.1.172.238; 5.1.172.239; 5.1.172.154; 5.1.172.157; 5.1.172.166; 5.1.172.169; 5.1.172.172; 5.1.172.175; 5.1.172.240; 5.1.172.244; 5.1.175.228; 5.1.175.229; 5.1.175.230; 5.1.175.231; 5.1.175.236; 5.1.175.237; 5.1.175.238; 5.1.175.239; 5.1.175.154; 5.1.175.157; 5.1.175.166; 5.1.175.169; 5.1.175.172; 5.1.175.175; 5.1.175.240; 5.1.175.244; 5.1.240.228; 5.1.240.229; 5.1.240.230; 5.1.240.231; 5.1.240.236; 5.1.240.237; 5.1.240.238; 5.1.240.239; 5.1.240.154; 5.1.240.157; 5.1.240.166; 5.1.240.169; 5.1.240.172; 5.1.240.175; 5.1.240.240; 5.1.240.244; 5.1.244.228; 5.1.244.229; 5.1.244.230; 5.1.244.231; 5.1.244.236; 5.1.244.237; 5.1.244.238; 5.1.244.239; 5.1.244.154; 5.1.244.157; 5.1.244.166; 5.1.244.169; 5.1.244.172; 5.1.244.175; 5.1.244.240; 5.1.244.244;

Prodrugs of 5.T

5.J.228.228; 5.J.228.229; 5.J.228.230; 5.J.228.231; 5.J.228.236; 5.J.228.237; 5.J.228.238; 5J.228.239; 5.J.228.154; 5.J.228.157; 5.J.228.166; 5.J.228.169; 5.J.228.172; 5.J.228.175; 5.J.228.240; 5.J.228.244; 5.J.229.228; 5.J.229.229; 5.J.229.230; 5.J.229.231; 5.J.229.236; 5.J.229.237; 5.J.229.238; 5.J.229.239; 5.J.229.154; 5.J.229.157; 5.J.229.166; 5.J.229.169; 5.J.229.172; 5.J.229.175; 5.J.229.240; 5.J.229.244; 5J.230.228; 5J.230.229; 5J.230.230; 5J.230.231; 5J.230.236; 5J.230.237; 5J.230.238; 5J.230.239; 5 J.230.154; 5.J.230.157; 5J.230.166; 5J.230.169; 5 J.230.172; 5 J.230.175; 5.J.230.24Q; 5J.230.244; 5J.231.228; 5J.231.229; 5J.231.230; 5J.231.231; 5J.231.236; 5J.231.237; 5J.231.238; 5J.231.239; 5 J.231.154; 5J.231.157; 5J.231.166; 5J.231.169; 5J.231.172; 5J.231.175; 5J.231.240; 5J.231.244; 5 J.236.228; 5J.236.229; 5J.236.230; 5J.236.231; 5J.236.236; 5J.236.237; 5J.236.238; 5.J.236.239; 5 J.236.154; 5 J.236.157; 5 J.236.166; 5 J.236.169; 5J.236.172; 5J.236.175; 5J.236.240; 5 J.236.244; 5.J.237.228; 5J.237.229; 5J.237.230; 5 J.237.231; 5.J.237.236; 5 J.237.237; 5J.237.238; 5J.237.239; 5 J.237.154; 5 J.237.157; 5J.237.166; 5 J.237.169; 5 J.237.172; 5J.237.175; 5.J.237.240; 5 J.237.244; 5 J.238.228; 5 J.238.229; 5 J.238.230; 5 J.238.231; 5J.238.236; 5 J.238.237; 5 J.238.238; 5J.238.239; 5 J.238.154; 5 J.238.157; 5J.238.166; 5 J.238.169; 5.J.238.172; 5J.238.175; 5J.238.240; 5J.238.244; 5 J.239.228; 5J.239.229; 5J.239.230; 5 J.239.231; 5 J.239.236; 5J.239.237; 5J.239.238; 5J.239.239; 5.J.239.154; 5J.239.157; 5 J.239.166; 5J.239.169; 5J.239.172; 5J.239.175; 5J.239.240; 5J.239.244; 5J.154.228; 5 J.154.229; 5J.154.230; 5J.154.231; 5.J.154.236; 5.J.154.237; 5.J.154.238; 5.J.154.239; 5J.154.154; 5.J.154.157; 5J.154.166; 5.J.154.169; 5J.154.172; 5 J.154.175; 5 J.154.240; 5J.154.244; 5 J.157.228; 5 J.157.229; 5J.157.230; 5.J.157.231; 5 J.157.236; 5J.157.237; 5J.157.238; 5J.157.239; 5 J.157.154; 5J.157.157; 5.J.157.166; 5J.157.169; 5J.157.172; 5 J.157.175; 5.J.157.240; 5J.157.244; 5 J.166.228; 5 J.166.229; 5J.166.230; 5.J.166.231; 5J.166.236; 5 J.166.237; 5 J.166.238; 5J.166.239; 5J.166.154; 5 J.166.157; 5.J.166.166; 5J.166.169; 5.J.166.172; 5J.166.175; 5J.166.240; 5J.166.244; 5.J.169.228; 5.J.169.229; 5 J.169.230; 5J.169.231; 5J.169.236; 5J.169.237; 5.J.169.238; 5 J.169.239; 5J.169.154; 5 J.169.157; 5J.169.166; 5 J.169.169; 5J.169.172; 5 J.169.175; 5 J.169.240; 5 J.169.244; 5 J.172.228; 5J.172.229; 5.J.172.230; 5J.172.231; 5.J.172.236; 5 J.172.237; 5.J.172.238; 5 J.172.239; 5 J.172.154; 5J.172.157; 5.J.172.166; 5J.172.169; 5J.172.172; 5 J.172.175; 5.J.172.240; 5J.172.244; 5.J.175.228; 5J.175.229; 5.J.175.230; 5J.175.231; 5 J.175.236; 5.J.175.237; 5J.175.238; 5J.175.239; 5J.175.154; 5J.175.157; 5J.175.166; 5J.175.169; 5J.175.172; 5J.175.175; 5J.175.240; 5.J.175.244; 5.J.240.228; 5 J.240.229; 5.J.240.230; 5J.240.231; 5J.240.236; 5 J.240.237; 5 J.240.238; 5.J.240.239; 5 J.240.154; 5 J.240.157; 5.J.240.166; 5J.240.169; 5 J.240.172; 5 J.240.175; 5J.240.240; 5.J.240.244; 5 J.244.228; 5J.244.229; 5J.244.230; 5.J.244.231; 5J.244.236; 5J.244.237; 5J.244.238; 5 J.244.239; 5J.244.154; 5.J.244.157; 5J.244.166; 5J.244.169; 5 J.244.172; 5J.244.175; 5J.244.240; 5.J.244.244;

Prodrugs of 5.L

5.L.228.228; 5.L.228.229; 5.L.228.230; 5.L.228.231; 5.L.228.236; 5.L.228.237; 5.L.228.238; 5.L.228.239; 5.L.228.154; 5.L.228.157; 5.L.228.166; 5.L.228.169; 5.L.228.172; 5.L.228.175; 5.L.228.240; 5.L.228.244; 5.L.229.228; 5.L.229.229; 5.L.229.230; 5.L.229.231; 5.L.229.236; 5.L.229.237; 5.L.229.238; 5.L.229.239; 5.L.229.154; 5.L.229.157; 5.L.229.166; 5.L.229.169; 5.L.229.172; 5.L.229.175; 5.L.229.240; 5.L.229.244; 5.L.230.228; 5.L.230.229; 5.L.230.230; 5.L.230.231; 5.L.230.236; 5.L.230.237; 5.L.230.238; 5.L.230.239; 5.L.230.154; 5.L.230.157; 5.L.230.166; 5.L.230.169; 5.L.230.172; 5.L.230.175; 5.L.230.240; 5X.230.244; 5.L.231.228; 5.L.231.229; 5.L.231.230; 5.L.231.231; 5.L.231.236; 5.L.231.237; 5.L.231.238; 5.L.231.239; 5.L.231.154; 5.L.231.157; 5.L.231.166; 5.L.231.169; 5.L.231.172; 5.L.231.175; 5.L.231.240; 5X.231.244; 5X.236.228; 5.L.236.229; 5X.236.230; 5X.236.231; 5X.236.236; 5X.236.237; 5X.236.238; 5X.236.239; 5.L.236.154; 5X.236.157; 5.L.236.166; 5X.236.169; 5X.236.172; 5X.236.175; 5X.236.240; 5X.236.244; 5X.237.228; 5X.237.229; 5X.237.230; 5X.237.231; 5X.237.236; 5X.237.237; 5X.237.238; 5X.237.239; 5X.237.154; 5X.237.157; 5X.237.166; 5X.237.169; 5X.237.172; 5X.237.175; 5X.237.240; 5X.237.244; 5X.238.228; 5X.238.229; 5X.238.230; 5X.238.231; 5X.238.236; 5X.238.237; 5X.238.238; 5X.238.239; 5X.238.154; 5X.238.157; 5X.238.166; 5X.238.169; 5X.238.172; 5X.238.175; 5X.238.240; 5X.238.244; 5X.239.228; 5X.239.229; 5X.239.230; 5X.239.231; 5X.239.236; 5X.239.237; 5X.239.238; 5X.239.239; 5X.239.154; 5X.239.157; 5X.239.166; 5X.239.169; 5X.239.172; 5X.239.175; 5X.239.240; 5X.239.244; 5.L.154.228; 5X.154.229; 5X.154.230; 5X.154.231; 5X.154.236; 5X.154.237; 5X.154.238; 5X.154.239; 5X.154.154; 5X.154.157; 5X.154.166; 5X.154.169; 5X.154.172; 5X.154.175; 5X.154.240; 5X.154.244; 5X.157.228; 5X.157.229; 5X.157.230; 5X.157.231; 5X.157.236; 5X.157.237; 5X.157.238; 5X.157.239; 5X.157.154; 5X.157.157; 5X.157.166; 5X.157.169; 5.L.157.172; 5.L.157.175; 5.L.157.240; 5.L.157.244; 5.L.166.228; 5.L.166.229; 5.L.166.230; 5.L.166.231; 5.L.166.236; 5.L.166.237; 5.L.166.238; 5.L.166.239; 5.L.166.154; 5.L.166.157; 5.L.166.166; 5.L.166.169; 5.L.166.172; 5.L.166.175; 5.L.166.240; 5.L.166.244; 5.L.169.228; 5.L.169.229; 5.L.169.230; 5.L.169.231; 5.L.169.236; 5.L.169.237; 5.L.169.238; 5.L.169.239; 5.L.169.154; 5.L.169.157; 5.L.169.166; 5.L.169.169; 5.L.169.172; 5.L.169.175; 5.L.169.240; 5.L.169.244; 5.L.172.228; 5.L.172.229; 5.L.172.230; 5.L.172.231; 5.L.172.236; 5.L.172.237; 5.L.172.238; 5.L.172.239; 5.L.172.154; 5.L.172.157; 5.L.172.166; 5.L.172.169; 5.L.172.172; 5.L.172.175; 5.L.172.240; 5.L.172.244; 5.L.175.228; 5.L.175.229; 5.L.175.230; 5.L.175.231; 5.L.175.236; 5.L.175.237; 5.L.175.238; 5.L.175.239; 5.L.175.154; 5.L.175.157; 5.L.175.166; 5.L.175.169; 5.L.175.172; 5.L.175.175; 5.L.175.240; 5.L.175.244; 5.L.240.228; 5.L.240.229; 5.L.240.230; 5.L.240.231; 5.L.240.236; 5.L.240.237; 5.L.240.238; 5.L.240.239; 5.L.240.154; 5.L.240.157; 5.L.240.166; 5.L.240.169; 5.L.240.172; 5.L.24Q.175; 5.L.24Q.240; 5.L.240.244; 5.L.244.228; 5.L.244.229; 5.L.244.230; 5.L.244.231; 5.L.244.236; 5.L.244.237; 5.L.244.238; 5.L.244.239; 5.L.244.154; 5.L.244.157; 5.L.244.166; 5.L.244.169; 5.L.244.172; 5.L.244.175; 5.L.244.240; 5.L.244.244;

Prodrugs of 5.O

5.O.228.228; 5.O.228.229; 5.O.228.230; 5.O.228.231; 5.O.228.236; 5.O.228.237; 5.O.228.238; 5.O.228.239; 5.O.228.154; 5.O.228.157; 5.O.228.166; 5.O.228.169; 5.O.228.172; 5.O.228.175; 5.O.228.240; 5.O.228.244; 5.O.229.228; 5.O.229.229; 5.O.229.230; 5.O.229.231; 5.O.229.236; 5.O.229.237; 5.O.229.238; 5.O.229.239; 5.O.229.154; 5.O.229.157; 5.O.229.166; 5.O.229.169; 5.O.229.172; 5.O.229.175; 5.O.229.240; 5.O.229.244; 5.O.230.228; 5.O.230.229; 5.O.230.230; 5.O.230.231; 5.O.230.236; 5.O.230.237; 5.O.230.238; 5.O.230.239; 5.O.230.154; 5.O.230.157; 5.O.230.166; 5.O.230.169; 5.O.230.172; 5.O.230.175; 5.O.230.240; 5.O.230.244; 5.O.231.228; 5.O.231.229; 5.O.231.230; 5.O.231.231; 5.O.231.236; 5.O.231.237; 5.O.231.238; 5.O.231.239; 5.O.231.154; 5.O.231.157; 5.O.231.166; 5.O.231.169; 5.O.231.172; 5.O.231.175; 5.O.231.240; 5.O.231.244; 5.O.236.228; 5.O.236.229; 5.O.236.230; 5.O.236.231; 5.O.236.236; 5.O.236.237; 5.O.236.238; 5.O.236.239; 5.O.236.154; 5.O.236.157; 5.O.236.166; 5.O.236.169; 5.O.236.172; 5.O.236.175; 5.O.236.240; 5.O.236.244; 5.O.237.228; 5.O.237.229; 5.O.237.230; 5.O.237.231; 5.O.237.236; 5.O.237.237; 5.O.237.238; 5.O.237.239; 5.O.237.154; 5.O.237.157; 5.O.237.166; 5.O.237.169; 5.O.237.172; 5.O.237.175; 5.O.237.240; 5.O.237.244; 5.O.238.228; 5.O.238.229; 5.O.238.230; 5.O.238.231; 5.O.238.236; 5.O.238.237; 5.O.238.238; 5.O.238.239; 5.O.238.154; 5.O.238.157; 5.O.238.166; 5.O.238.169; 5.O.238.172; 5.O.238.175; 5.O.238.240; 5.O.238.244; 5.O.239.228; 5.O.239.229; 5.O.239.230; 5.O.239.231; 5.O.239.236; 5.O.239.237; 5.O.239.238; 5.O.239.239; 5.O.239.154; 5.O.239.157; 5.O.239.166; 5.O.239.169; 5.O.239.172; 5.O.239.175; 5.O.239.240; 5.O.239.244; 5.O.154.228; 5.O.154.229; 5.O.154.230; 5.O.154.231; 5.O.154.236; 5.O.154.237; 5.O.154.238; 5.O.154.239; 5.O.154.154; 5.O.154.157; 5.O.154.166; 5.O.154.169; 5.O.154.172; 5.O.154.175; 5.O.154.240; 5.O.154.244; 5.O.157.228; 5.O.157.229; 5.O.157.230; 5.O.157.231; 5.O.157.236; 5.O.157.237; 5.O.157.238; 5.O.157.239; 5.O.157.154; 5.O.157.157; 5.O.157.166; 5.O.157.169; 5.O.157.172; 5.O.157.175; 5.O.157.240; 5.O.157.244; 5.O.166.228; 5.O.166.229; 5.O.166.230; 5.O.166.231; 5.O.166.236; 5.O.166.237; 5.O.166.238; 5.O.166.239; 5.O.166.154; 5.O.166.157; 5.O.166.166; 5.O.166.169; 5.O.166.172; 5.O.166.175; 5.O.166.240; 5.O.166.244; 5.O.169.228; 5.O.169.229; 5.O.169.230; 5.O.169.231; 5.O.169.236; 5.O.169.237; 5.O.169.238; 5.O.169.239; 5.O.169.154; 5.O.169.157; 5.O.169.166; 5.O.169.169; 5.O.169.172; 5.O.169.175; 5.O.169.240; 5.O.169.244; 5.O.172.228; 5.O.172.229; 5.O.172.230; 5.O.172.231; 5.O.172.236; 5.O.172.237; 5.O.172.238; 5.O.172.239; 5.O.172.154; 5.O.172.157; 5.O.172.166; 5.O.172.169; 5.O.172.172; 5.O.172.175; 5.O.172.240; 5.O.172.244; 5.O.175.228; 5.O.175.229; 5.O.175.230; 5.O.175.231; 5.O.175.236; 5.O.175.237; 5.O.175.238; 5.O.175.239; 5.O.175.154; 5.O.175.157; 5.O.175.166; 5.O.175.169; 5.O.175.172; 5.O.175.175; 5.O.175.240; 5.O.175.244; 5.O.240.228; 5.O.240.229; 5.O.240.230; 5.O.240.231; 5.O.240.236; 5.O.240.237; 5.O.24Q.238; 5.O.240.239; 5.O.240.154; 5.O.240.157; 5.O.240.166; 5.O.240.169; 5.O.240.172; 5.O.240.175; 5.O.24Q.240; 5.O.240.244; 5.O.244.228; 5.O.244.229; 5.O.244.230; 5.O.244.231; 5.O.244.236; 5.O.244.237; 5.O.244.238; 5.O.244.239; 5.O.244.154; 5.O.244.157; 5.O.244.166; 5.O.244.169; 5.O.244.172; 5.O.244.175; 5.O.244.240; 5.O.244.244;

Prodrugs of 5.F

5.P.228.228; 5.P.228.229; 5.P.228.230; 5.P.228.231; 5.P.228.236; 5.P.228.237; 5.P.228.238; 5.P.228.239; 5.P.228.154; 5.P.228.157; 5.P.228.166; 5.P.228.169; 5.P.228.172; 5.P.228.175; 5.P.228.240; 5.P.228.244; 5.P.229.228; 5.P.229.229; 5.P.229.230; 5.P.229.231; 5.P.229.236; 5.P.229.237; 5.P.229.238; 5.P.229.239; 5.P.229.154; 5.P.229.157; 5.P.229.166; 5.P.229.169; 5.P.229.172; 5.P.229.175; 5.P.229.240; 5.P.229.244; 5.P.230.228; 5.P.230.229; 5.P.230.230; 5.P.230.231; 5.P.230.236; 5.P.230.237; 5.P.230.238; 5.P.230.239; 5.P.230.154; 5.P.230.157; 5.P.230.166; 5.P.230.169; 5.P.230.172; 5.P.230.175; 5.P.230.240; 5.P.230.244; 5.P.231.228; 5.P.231.229; 5.P.231.230; 5.P.231.231; 5.P.231.236; 5.P.231.237; 5.P.231.238; 5.P.231.239; 5.P.231.154; 5.P.231.157; 5.P.231.166; 5.P.231.169; 5.P.231.172; 5.P.231.175; 5.P.231.240; 5.P.231.244; 5.P.236.228; 5.P.236.229; 5.P.236.230; 5.P.236.231; 5.P.236.236; 5.P.236.237; 5.P.236.238; 5.P.236.239; 5.P.236.154; 5.P.236.157; 5.P.236.166; 5.P.236.169; 5.P.236.172; 5.P.236.175; 5.P.236.240; 5.P.236.244; 5.P.237.228; 5.P.237.229; 5.P.237.230; 5.P.237.231; 5.P.237.236; 5.P.237.237; 5.P.237.238; 5.P.237.239; 5.P.237.154; 5.P.237.157; 5.P.237.166; 5.P.237.169; 5.P.237.172; 5.P.237.175; 5.P.237.240; 5.P.237.244; 5.P.238.228; 5.P.238.229; 5.P.238.230; 5.P.238.231; 5.P.238.236; 5.P.238.237; 5.P.238.238; 5.P.238.239; 5.P.238.154; 5.P.238.157; 5.P.238.166; 5.P.238.169; 5.P.238.172; 5.P.238.175; 5.P.238.240; 5.P.238.244; 5.P.239.228; 5.P.239.229; 5.P.239.230; 5.P.239.231; 5.P.239.236; 5.P.239.237; 5.P.239.238; 5.P.239.239; 5.P.239.154; 5.P.239.157; 5.P.239.166; 5.P.239.169; 5.P.239.172; 5.P.239.175; 5.P.239.240; 5.P.239.244; 5.P.154.228; 5.P.154.229; 5.P.154.230; 5.P.154.231; 5.P.154.236; 5.P.154.237; 5.P.154.238; 5.P.154.239; 5.P.154.154; 5.P.154.157; 5.P.154.166; 5.P.154.169; 5.P.154.172; 5.P.154.175; 5.P.154.240; 5.P.154.244; 5.P.157.228; 5.P.157.229; 5.P.157.230; 5.P.157.231; 5.P.157.236; 5.P.157.237; 5.P.157.238; 5.P.157.239; 5.P.157.154; 5.P.157.157; 5.P.157.166; 5.P.157.169; 5.P.157.172; 5.P.157.175; 5.P.157.240; 5.P.157.244; 5.P.166.228; 5.P.166.229; 5.P.166.230; 5.P.166.231; 5.P.166.236; 5.P.166.237; 5.P.166.238; 5.P.166.239; 5.P.166.154; 5.P.166.157; 5.P.166.166; 5.P.166.169; 5.P.166.172; 5.P.166.175; 5.P.166.240; 5.P.166.244; 5.P.169.228; 5.P.169.229; 5.P.169.230; 5.P.169.231; 5.P.169.236; 5.P.169.237; 5.P.169.238; 5.P.169.239; 5.P.169.154; 5.P.169.157; 5.P.169.166; 5.P.169.169; 5.P.169.172; 5.P.169.175; 5.P.169.240; 5.P.169.244; 5.P.172.228; 5.P.172.229; 5.P.172.230; 5.P.172.231; 5.P.172.236; 5.P.172.237; 5.P.172.238; 5.P.172.239; 5.P.172.154; 5.P.172.157; 5.P.172.166; 5.P.172.169; 5.P.172.172; 5.P.172.175; 5.P.172.240; 5.P.172.244; 5.P.175.228; 5.P.175.229; 5.P.175.230; 5.P.175.231; 5.P.175.236; 5.P.175.237; 5.P.175.238; 5.P.175.239; 5.P.175.154; 5.P.175.157; 5.P.175.166; 5.P.175.169; 5.P.175.172; 5.P.175.175; 5.P.175.240; 5.P.175.244; 5.P.240.228; 5.P.240.229; 5.P.240.230; 5.P.240.231; 5.P.240.236; 5.P.240.237; 5.P.240.238; 5.P.240.239; 5.P.240.154; 5.P.240.157; 5.P.240.166; 5.P.24Q.169; 5.P.240.172; 5.P.240.175; 5.P.240.240; 5.P.240.244; 5.P.244.228; 5.P.244.229; 5.P.244.23Q; 5.P.244.231; 5.P.244.236; 5.P.244.237; 5.P.244.238; 5.P.244.239; 5.P.244.154; 5.P.244.157; 5.P.244.166; 5.P.244.169; 5.P.244.172; 5.P.244.175; 5.P.244.240; 5.P.244.244;

Prodrugs of 5.U

5.U.228.228; 5.U.228.229; 5.U.228.230; 5.U.228.231; 5.U.228.236; 5.U.228.237; 5.U.228.238; 5.U.228.239; 5.U.228.154; 5.U.228.157; 5.U.228.166; 5.U.228.169; 5.U.228.172; 5.U.228.175; 5.U.228.240; 5.U.228.244; 5.U.229.228; 5.U.229.229; 5.U.229.230; 5.U.229.231; 5.U.229.236; 5.U.229.237; 5.U.229.238; 5.U.229.239; 5.U.229.154; 5.U.229.157; 5.U.229.166; 5.U.229.169; 5.U.229.172; 5.U.229.175; 5.U.229.240; 5.U.229.244; 5.U.230.228; 5.U.230.229; 5.U.230.230; 5.U.230.231; 5.U.230.236; 5.U.230.237; 5.U.230.238; 5.U.230.239; 5.U.230.154; 5.U.230.157; 5.U.230.166; 5.U.230.169; 5.U.230.172; 5.U.230.175; 5.U.230.240; 5.U.230.244; 5.U.231.228; 5.U.231.229; 5.U.231.230; 5.U.231.231; 5.U.231.236; 5.U.231.237; 5.U.231.238; 5.U.231.239; 5.U.231.154; 5.U.231.157; 5.U.231.166; 5.U.231.169; 5.U.231.172; 5.U.231.175; 5.U.231.240; 5.U.231.244; 5.U.236.228; 5.U.236.229; 5.U.236.230; 5.U.236.231; 5.U.236.236; 5.U.236.237; 5.U.236.238; 5.U.236.239; 5.U.-236.154; 5.U.236.157; 5.U.236.166; 5.U.236.169; 5.U.236.172; 5.U.236.175; 5.U.236.240; 5.U.236.244; 5.U.237.228; 5.U.237.229; 5.U.237.230; 5.U.237.231; 5.U.237.236; 5.U.237.237; 5.U.237.238; 5.U.237.239; 5.U.237.154; 5.U.237.157; 5.U.237.166; 5.U.237.169; 5.U.237.172; 5.U.237.175; 5.U.237.240; 5.U.237.244; 5.U.238.228; 5.U.238.229; 5.U.238.230; 5.U.238.231; 5.U.238.236; 5.U.238.237; 5.U.238.238; 5.U.238.239; 5.U.238.154; 5.U.238.157; 5.U.238.166; 5.U.238.169; 5.U.238.172; 5.U.238.175; 5.U.238.240; 5.U.238.244; 5.U.239.228; 5.U.239.229; 5.U.239.230; 5.U.239.231; 5.U.239.236; 5.U.239.237; 5.U.239.238; 5.U.239.239; 5.U.239.154; 5.U.239.157; 5.U.239.166; 5.U.239.169; 5.U.239.172; 5.U.239.175; 5.U.239.240; 5.U.239.244; 5.U.154.228; 5.U.154.229; 5.U.154.230; 5.U.154.231; 5.U.154.236; 5.U.154.237; 5.U.154.238; 5.U.154.239; 5.U.154.154; 5.U.154.157; 5.U.154.166; 5.U.154.169; 5.U.154.172; 5.U.154.175; 5.U.154.240; 5.U.154.244; 5.U.157.228; 5.U.157.229; 5.U.157.230; 5.U.157.231; 5.U.157.236; 5.U.157.237; 5.U.157.238; 5.U.157.239; 5.U.157.154; 5.U.157.157; 5.U.157.166; 5.U.157.169; 5.U.157.172; 5.U.157.175; 5.U.157.240; 5.U.157.244; 5.U.166.228; 5.U.166.229; 5.U.166.230; 5.U.166.231; 5.U.166.236; 5.U.166.237; 5.U.166.238; 5.U.166.239; 5.U.166.154; 5.U.166.157; 5.U.166.166; 5.U.166.169; 5.U.166.172; 5.U.166.175; 5.U.166.240; 5.U.166.244; 5.U.169.228; 5.U.169.229; 5.U.169.230; 5.U.169.231; 5.U.169.236; 5.U.169.237; 5.U.169.238; 5.U.169.239; 5.U.169.154; 5.U.169.157; 5.U.169.166; 5.U.169.169; 5.U.169.172; 5.U.169.175; 5.U.169.240; 5.U.169.244; 5.U.172.228; 5.U.172.229; 5.U.172.230; 5.U.172.231; 5.U.172.236; 5.U.172.237; 5.U.172.238; 5.U.172.239; 5.U.172.154; 5.U.172.157; 5.U.172.166; 5.U.172.169; 5.U.172.172; 5.U.172.175; 5.U.172.240; 5.U.172.244; 5.U.175.228; 5.U.175.229; 5.U.175.230; 5.U.175.231; 5.U.175.236; 5.U.175.237; 5.U.175.238; 5.U.175.239; 5.U.175.154; 5.U.175.157; 5.U.175.166; 5.U.175.169; 5.U.175.172; 5.U.175.175; 5.U.175.240; 5.U.175.244; 5.U.240.228; 5.U.240.229; 5.U.240.230; 5.U.240.231; 5.U.240.236; 5.U.240.237; 5.U.240.238; 5.U.24Q.239; 5.U.240.154; 5.U.240.157; 5.U.240.166; 5.U.240.169; 5.U.240.172; 5.U.240.175; 5.U.240.240; 5.U.240.244; 5.U.244.228; 5.U.244.229; 5.U.244.230; 5.U.244.231; 5.U.244.236; 5.U.244.237; 5.U.244.238; 5.U.244.239; 5.U.244.154; 5.U.244.157; 5.U.244.166; 5.U.244.169; 5.U.244.172; 5.U.244.175; 5.U.244.240; 5.U.244.244;

Prodrugs of 5.CD

5.CD.228.228; 5.CD.228.229; 5.CD.228.230; 5.CD.228.231; 5.CD.228.236; 5.CD.228.237; 5.CD.228.238; 5.CD.228.239; 5.CD.228.154; 5.CD.228.157; 5.CD.228.166; 5.CD.228.169; 5.CD.228.172; 5.CD.228.175; 5.CD.228.240; 5.CD.228.244; 5.CD.229.228; 5.CD.229.229; 5.CD.229.230; 5.CD.229.231; 5.CD.229.236; 5.CD.229.237; 5.CD.229.238; 5.CD.229.239; 5.CD.229.154; 5.CD.229.157; 5.CD.229.166; 5. CD.229.169; 5.CD.229.172; 5. CD.229.175; 5.CD.229.240; 5.CD.229.244; 5.CD.230.228; 5.CD.230.229; 5.CD.230.230; 5.CD.230.231; 5.CD.230.236; 5.CD.230.237; 5.CD.230.238; 5.CD.230.239; 5.CD.230.154; 5.CP.230.157; 5.CD.230.166; 5.CD.230.169; 5.CD.230.172; 5.CD.230.175; 5.CD.230.24Q; 5.CD.23Q.244; 5.CD.231.228; 5.CD.231.229; 5.CD.231.230; 5.CD.231.231; 5.CD.231.236; 5.CD.231.237; 5.CD.231.238; 5.CD.231.239; 5.CD.231.154; 5.CD.231.157; 5.CD.231.166; 5.CD.231.169; 5.CD.231.172; 5.CD.231.175; 5.CD.231.240; 5.CD.231.244; 5.CD.236.228; 5.CD.236.229; 5.CD.236.230; 5.CD.236.231; 5.CD.236.236; 5.CD.236.237; 5.CD.236.238; 5.CD.236.239; 5.CD.236.154; 5.CD.236.157; 5.CD.236.166; 5.CD.236.169; 5.CD.236.172; 5.CD.236.175; 5.CD.236.240; 5.CD.236.244; 5.CD.237.228; 5.CD.237.229; 5.CD.237.230; 5.CD.237.231; 5.CD.237.236; 5.CD.237.237; 5.CD.237.238; 5.CD.237.239; 5.CD.237.154; 5.CD.237.157; 5.CD.237.166; 5.CD.237.169; 5.CD.237.172; 5.CD.237.175; 5.CD.237.240; 5.CD.237.244; 5.CD.238.228; 5.CD.238.229; 5.CD.238.230; 5.CD.238.231; 5.CD.238.236; 5.CD.238.237; 5.CD.238.238; 5.CD.238.239; 5.CD.238.154; 5.CD.238.157; 5.CD.238.166; 5.CD.238.169; 5.CD.238.172; 5.CD.238.175; 5.CD.238.240; 5.CD.238.244; 5.CD.239.228; 5.CD.239.229; 5.CD.239.230; 5.CD.239.231; 5.CD.239.236; 5.CD.239.237; 5.CD.239.238; 5.CD.239.239; 5.CD.239.154; 5.CD.239.157; 5.CD.239.166; 5.CD.239.169; 5.CD.239.172; 5.CD.239.175; 5.CD.239.240; 5.CD.239.244; 5.CD.154.228; 5.CD.154.229; 5.CD.154.230; 5.CD.154.231; 5.CD.154.236; 5.CD.154.237; 5.CD.154.238; 5.CD.154.239; 5.CD.154.154; 5.CD.154.157; 5.CD.154.166; 5.CD.154.169; 5.CD.154.172; 5.CD.154.175; 5.CD.154.240; 5.CD.154.244; 5.CD.157.228; 5.CD.157.229; 5.CD.157.230; 5.CD.157.231; 5.CD.157.236; 5.CD.157.237; 5.CD.157.238; 5. CD.157.239; 5.CD.157.154; 5. CO.157.157; 5.CD.157.166; 5.CD.157.169; 5.CD.157.172; 5.CD.157.175; 5.CD.157.240; 5.CD.157.244; 5.CD.166.228; 5.CD.166.229; 5.CD.166.230; 5.CD.166.231; 5.CD.166.236; 5.CD.166.237; 5.CD.166.238; 5.CD.166.239; 5.CD.166.154; 5.CD.166.157; 5.CD.166.166; 5.CD.166.169; 5.CD.166.172; 5.CD.166.175; 5.CD.166.24Q; 5.CD.166.244; 5.CD.169.228; 5.CD.169.229; 5.CD.169.230; 5.CD.169.231; 5.CD.169.236; 5.CD.169.237; 5.CD.169.238; 5.CD.169.239; 5.CD.169.154; 5.CD.169.157; 5.CD.169.166; 5.CD.169.169; 5.CD.169.172; 5.CEU69.175; 5.CD.169.240; 5.CD.169.244; 5.CD.172.228; 5.CD.172.229; 5.CD.172.230; 5.CD.172.231; 5.CD.172.236; 5.CD.172.237; 5.CD.172.238; 5.CD.172.239; 5.CD.172.154; 5.CD.172.157; 5.CD.172.166; 5.CD.172.169; 5.CD.172.172; 5.CD.172.175; 5.CD.172.240; 5.CD.172.244; 5.CD.175.228; 5.CD.175.229; 5.CD.175.230; 5.CD.175.231; 5.CD.175.236; 5.CD.175.237; 5.CP.175.238; 5.CD.175.239; 5.CD.175.154; 5.CD.175.157; 5.CD.175.166; 5.CEU75.169; 5.CD.175.172; 5.CD.175.175; 5.CD.175.240; 5.CD.175.244; 5.CD.240.228; 5.CD.240.229; 5.CD.240.230; 5.CD.240.231; 5.CD.240.236; 5.CD.240.237; 5.CD.240.238; 5.CD.240.239; 5.CD.24Q.154; 5.CD.240.157; 5.CD.240.166; 5.CD.240.169; 5. CD.240.172; 5.CD.240.175; 5.CD.240.240; 5.CD.24Q.244; 5.CD.244.228; 5.CD.244.229; 5.CD.244.230; 5.CD.244.231; 5.CD.244.236; 5.CD.244.237; 5.CD.244.238; 5.CD.244.239; 5.CD.244.154; 5.CD.244.157; 5.CD.244.166; 5.CD.244.169; 5.CD.244.172; 5.CD.244.175; 5.CD.244.240; 5.CD.244.244;

Prodrugs of 5.EB

5.EB.228.228; 5.EB.228.229; 5.EB.228.230; 5.EB.228.231; 5.EB.228.236; 5.EB.228.237; 5.EB.228.238; 5.EB.228.239; 5.EB.228.154; 5.EB.228.157; 5.EB.228.166; 5.EB.228.169; 5.EB.228.172; 5.EB.228.175; 5.EB.228.240; 5.EB.228.244; 5.EB.229.228; 5.EB.229.229; 5.EB.229.230; 5.EB.229.231; 5.EB.229.236; 5.EB.229.237; 5.EB.229.238; 5.EB.229.239; 5.EB.229.154; 5.EB.229.157; 5.EB.229.166; 5.EB.229.169; 5.EB.229.172; 5.EB.229.175; 5.EB.229.240; 5.EB.229.244; 5.EB.230.228; 5.EB.230.229; 5.EB.230.230; 5.EB.230.231; 5.EB.23Q.236; 5.EB.23Q.237; 5.EB.230.238; 5.EB.230.239; 5.EB.230.154; 5.EB.230.157; 5.EB.230.166; 5.EB.230.169; 5.EB.230.172; 5.EB.230.175; 5.EB.230.240; 5.EB.230.244; 5.EB.231.228; 5.EB.231.229; 5.EB.231.230; 5.EB.231.231; 5.EB.231.236; 5.EB.231.237; 5.EB.231.238; 5.EB.231.239; 5.EB.231.154; 5.EB.231.157; 5.EB.231.166; 5.EB.231.169; 5.EB.231.172; 5.EB.231.175; 5.EB.231.240; 5.EB.231.244; 5.EB.236.228; 5.EB.236.229; 5.EB.236.230; 5.EB.236.231; 5.EB.236.236; 5.EB.236.237; 5.EB.236.238; 5.EB.236.239; 5.EB.236.154; 5.EB.236.157; 5.EB.236.166; 5.EB.236.169; 5.EB.236.172; 5.EB.236.175; 5.EB.236.240; 5.EB.236.244; 5.EB.237.228; 5.EB.237.229; 5.EB.237.230; 5.EB.237.231; 5.EB.237.236; 5.EB.237.237; 5.EB.237.238; 5.EB.237.239; 5.EB.237.154; 5.EB.237.157; 5.EB.237.166; 5.EB.237.169; 5.EB.237.172; 5.EB.237.175; 5.EB.237.240; 5.EB.237.244; 5.EB.238.228; 5.EB.238.229; 5.EB.238.230; 5.EB.238.231; 5.EB.238.236; 5.EB.238.237; 5.EB.238.238; 5.EB.238.239; 5.EB.238.154; 5.EB.238.157; 5.EB.238.166; 5.EB.238.169; 5.EB.238.172; 5.EB.238.175; 5.EB.238.240; 5.EB.238.244; 5.EB.239.228; 5.EB.239.229; 5.EB.239.230; 5.EB.239.231; 5.EB.239.236; 5.EB.239.237; 5.EB.239.238; 5.EB.239.239; 5.EB.239.154; 5.EB.239.157; 5.EB.239.166; 5.EB.239.169; 5.EB.239.172; 5.EB.239.175; 5.EB.239.240; 5.EB.239.244; 5.EB.154.228; 5.EB.154.229; 5.EB.154.230; 5.EB.154.231; 5.EB.154.236; 5.EB.154.237; 5.EB.154.238; 5.EB.154.239; 5.EB.154.154; 5.EB.154.157; 5.EB.154.166; 5.EB.154.169; 5.EB.154.172; 5.EB.154.175; 5.EB.154.240; 5.EB.154.244; 5.EB.157.228; 5.EB.157.229; 5.EB.157.230; 5.EB.157.231; 5.EB.157.236; 5.EB.157.237; 5.EB.157.238; 5.EB.157.239; 5.EB.157.154; 5.EB.157.157; 5.EB.157.166; 5.EB.157.169; 5.EB.157.172; 5.EB.157.175; 5.EB.157.240; 5.EB.157.244; 5.EB.166.228; 5.EB.166.229; 5.EB.166.230; 5.EB.166.231; 5.EB.166.236; 5.EB.166.237; 5.EB.166.238; 5.EB.166.239; 5.EB.166.154; 5.EB.166.157; 5.EB.166.166; 5.EB.166.169; 5.EB.166.172; 5.EB.166.175; 5.EB.166.240; 5.EB.166.244; 5.EB.169.228; 5.EB.169.229; 5.EB.169.230; 5.EB.169.231; 5.EB.169.236; 5.EB.169.237; 5.EB.169.238; 5.EB.169.239; 5.EB.169.154; 5.EB.169.157; 5.EB.169.166; 5.EB.169.169; 5.EB.169.172; 5.EB.169.175; 5.EB.169.240; 5.EB.169.244; 5.EB.172.228; 5.EB.172.229; 5.EB.172.230; 5.EB.172.231; 5.EB.172.236; 5.EB.172.237; 5.EB.172.238; 5.EB.172.239; 5.EB.172.154; 5.EB.172.157; 5.EB.172.166; 5.EB.172.169; 5.EB.172.172; 5.EB.172.175; 5.EB.172.240; 5.EB.172.244; 5.EB.175.228; 5.EB.175.229; 5.EB.175.230; 5.EB.175.231; 5.EB.175.236; 5.EB.175.237; 5.EB.175.238; 5.EB.175.239; 5.EB.175.154; 5.EB.175.157; 5.EB.175.166; 5.EB.175.169; 5.EB.175.172; 5.EB.175.175; 5.EB.175.240; 5.EB.175.244; 5.EB.240.228; 5.EB.240.229; 5.EB.240.230; 5.EB.24Q.231; 5.EB.240.236; 5.EB.240.237; 5.EB.240.238; 5.EB.240.239; 5.EB.240.154; 5.EB.240.157; 5.EB.240.166; 5.EB.240.169; 5.EB.240.172; 5.EB.240.175; 5.EB.240.240; 5.EB.240.244; 5.EB.244.228; 5.EB.244.229; 5.EB.244.230; 5.EB.244.231; 5.EB.244.236; 5.EB.244.237; 5.EB.244.238; 5.EB.244.239; 5.EB.244.154; 5.EB.244.157; 5.EB.244.166; 5.EB.244.169; 5.EB.244.172; 5.EB.244.175; 5.EB.244.240; 5.EB.244.244;

Prodrugs of 6.B

6.B.228.228; 6.B.228.229; 6.B.228.230; 6.B.228.231; 6.B.228.236; 6.B.228.237; 6.B.228.238; 6.B.228.239; 6.B.228.154; 6.B.228.157; 6.B.228.166; 6.B.228.169; 6.B.228.172; 6.B.228.175; 6.B.228.240; 6.B.228.244; 6.B.229.228; 6.B.229.229; 6.B.229.230; 6.B.229.231; 6.B.229.236; 6.B.229.237; 6.B.229.238; 6.B.229.239; 6.B.229.154; 6.B.229.157; 6.B.229.166; 6.B.229.169; 6.B.229.172; 6.B.229.175; 6.B.229.240; 6.B.229.244; 6.B.23Q.228; 6.B.230.229; 6.B.230.230; 6.B.230.231; 6.B.230.236; 6.B.230.237; 6.B.230.238; 6.B.230.239; 6.B.230.154; 6.B.230.157; 6.B.230.166; 6.B.230.169; 6.B.230.172; 6.B.230.175; 6.B.230.240; 6.B.230.244; 6.B.231.228; 6.B.231.229; 6.B.231.230; 6.B.231.231; 6.B.231.236; 6.B.231.237; 6.B.231.238; 6.B.231.239; 6.B.231.154; 6.B.231.157; 6.B.231.166; 6.B.231.169; 6.B.231.172; 6.B.231.175; 6.B.231.240; 6.B.231.244; 6.B.236.228; 6.B.236.229; 6.B.236.230; 6.B.236.231; 6.B.236.236; 6.B.236.237; 6.B.236.238; 6.B.236.239; 6.B.236.154; 6.B.236.157; 6.B.236.166; 6.B.236.169; 6.B.236.172; 6.B.236.175; 6.B.236.240; 6.B.236.244; 6.B.237.228; 6.B.237.229; 6.B.237.230; 6.B.237.231; 6.B.237.236; 6.B.237.237; 6.B.237.238; 6.B.237.239; 6.B.237.154; 6.B.237.157; 6.B.237.166; 6.B.237.169; 6.B.237.172; 6.B.237.175; 6.B.237.240; 6.B.237.244; 6.B.238.228; 6.B.238.229; 6.B.238.230; 6.B.238.231; 6.B.238.236; 6.B.238.237; 6.B.238.238; 6.B.238.239; 6.B.238.154; 6.B.238.157; 6.B.238.166; 6.B.238.169; 6.B.238.172; 6.B.238.175; 6.B.238.240; 6.B.238.244; 6.B.239.228; 6.B.239.229; 6.B.239.230; 6.B.239.231; 6.B.239.236; 6.B.239.237; 6.B.239.238; 6.B.239.239; 6.B.239.154; 6.B.239.157; 6.B.239.166; 6.B.239.169; 6.B.239.172; 6.B.239.175; 6.B.239.240; 6.B.239.244; 6.B.154.228; 6.B.154.229; 6.B.154.230; 6.B.154.231; 6.B.154.236; 6.B.154.237; 6.B.154.238; 6.B.154.239; 6.B.154.154; 6.B.154.157; 6.B.154.166; 6.B.154.169; 6.B.154.172; 6.B.154.175; 6.B.154.240; 6.B.154.244; 6.B.157.228; 6.B.157.229; 6.B.157.230; 6.B.157.231; 6.B.157.236; 6.B.157.237; 6.B.157.238; 6.B.157.239; 6.B.157.154; 6.B.157.157; 6.B.157.166; 6.B.157.169; 6.B.157.172; 6.B.157.175; 6.B.157.240; 6.B.157.244; 6.B.166.228; 6.B.166.229; 6.B.166.230; 6.B.166.231; 6.B.166.236; 6.B.166.237; 6.B.166.238; 6.B.166.239; 6.B.166.154; 6.B.166.157; 6.B.166.166; 6.B.166.169; 6.B.166.172; 6.B.166.175; 6.B.166.240; 6.B.166.244; 6.B.169.228; 6.B.169.229; 6.B.169.230; 6.B.169.231; 6.B.169.236; 6.B.169.237; 6.B.169.238; 6.B-169.239; 6.B.169.154; 6.B.169.157; 6.B.169.166; 6.B.169.169; 6.B.169.172; 6.B.169.175; 6.B.169.240; 6.B.169.244; 6.B.172.228; 6.B.172.229; 6.B.172.230; 6.B.172.231; 6.B.172.236; 6.B.172.237; 6.B.172.238; 6.B-172.239; 6.B.172.154; 6.B.172.157; 6.B.172.166; 6.B.172.169; 6.B.172.172; 6.B.172.175; 6.B.172.240; 6.B.172.244; 6.B.175.228; 6.B.175.229; 6.B.175.230; 6.B.175.231; 6.B.175.236; 6.B.175.237; 6.B.175.238; 6.B.175.239; 6.B.175.154; 6.B.175.157; 6.B.175.166; 6.B.175.169; 6.B.175.172; 6.B.175.175; 6.B.175.240; 6.B.175.244; 6.B.240.228; 6.B.24Q.229; 6.B.240.230; 6.B.240.231; 6.B.240.236; 6.B.240.237; 6.B.240.238; 6.B.240.239; 6.B.240.154; 6.B.240.157; 6.B.240.166; 6.B.240.169; 6.B.240.172; 6.B.240.175; 6.B.240.240; 6.B.240.244; 6.B.244.228; 6.B.244.229; 6.B.244.230; 6.B.244.231; 6.B.244.236; 6.B.244.237; 6.B.244.238; 6.B.244.239; 6.B.244.154; 6.B.244.157; 6.B.244.166; 6.B.244.169; 6.B.244.172; 6.B.244.175; 6.B.244.240; 6.B.244.244;

Prodrugs of 6.D

6.D.228.228; 6.D.228.229; 6.D.228.230; 6.D.228.231; 6.D.228.236; 6.D.228.237; 6.D.228.238; 6.D.228.239; 6.D.228.154; 6.D.228.157; 6.D.228.166; 6.D.228.169; 6.D.228.172; 6.D.228.175; 6.D.228.240; 6.D.228.244; 6.D.229.228; 6.D.229.229; 6.D.229.230; 6.D.229.231; 6.D.229.236; 6.D.229.237; 6.D.229.238; 6.D.229.239; 6.D.229.154; 6.D.229.157; 6.D.229.166; 6.D.229.169; 6.D.229.172; 6.D.229.175; 6.D.229.240; 6.D.229.244; 6.D.23Q.228; 6.D.230.229; 6.D.230.230; 6.D.230.231; 6.D.23Q.236; 6.D.230.237; 6.D.230.238; 6.D.230.239; 6.D.230.154; 6.D.230.157; 6.D.230.166; 6.D.230.169; 6.D.230.172; 6.D.230.175; 6.D.230.240; 6.D.230.244; 6.D.231.228; 6.D.231.229; 6.D.231.230; 6.D.231.231; 6.D.231.236; 6.D.231.237; 6.D.231.238; 6.D.231.239; 6.D.231.154; 6.D.231.157; 6.D.231.166; 6.D.231.169; 6.D.231.172; 6.D.231.175; 6.D.231.240; 6.D.231.244; 6.D.236.228; 6.D.236.229; 6.D.236.230; 6.D.236.231; 6.D.236.236; 6.D.236.237; 6.D.236.238; 6.D.236.239; 6.D.236.154; 6.D.236.157; 6.D.236.166; 6.D.236.169; 6.D.236.172; 6.D.236.175; 6.D.236.240; 6.D.236.244; 6.D.237.228; 6.D.237.229; 6.D.237.230; 6.D.237.231; 6.D.237.236; 6.D.237.237; 6.D.237.238; 6.D.237.239; 6.D.237.154; 6.D.237.157; 6.D.237.166; 6.D.237.169; 6.D.237.172; 6.D.237.175; 6.D.237.240; 6.D.237.244; 6.D.238.228; 6.D.238.229; 6.D.238.230; 6.D.238.231; 6.D.238.236; 6.D.238.237; 6.D.238.238; 6.D.238.239; 6.D.238.154; 6.D.238.157; 6.D.238.166; 6.D.238.169; 6.D.238.172; 6.D.238.175; 6.D.238.240; 6.D.238.244; 6.D.239.228; 6.D.239.229; 6.D.239.230; 6.D.239.231; 6.D.239.236; 6.D.239.237; 6.D.239.238; 6.D.239.239; 6.D.239.154; 6.D.239.157; 6.D.239.166; 6.D.239.169; 6.D.239.172; 6.D.239.175; 6.D.239.240; 6.D.239.244; 6.D.154.228; 6.D.154.229; 6.D.154.230; 6.D.154.231; 6.D.154.236; 6.D.154.237; 6.D.154.238; 6.D.154.239; 6.D.154.154; 6.D.154.157; 6.D.154.166; 6.D.154.169; 6.D.154.172; 6.D.154.175; 6.D.154.240; 6.D.154.244; 6.D.157.228; 6.D.157.229; 6.D.157.230; 6.D.157.231; 6.D.157.236; 6.D.157.237; 6.D.157.238; 6.D.157.239; 6.D.157.154; 6.D.157.157; 6.D.157.166; 6.D.157.169; 6.D.157.172; 6.D.157.175; 6.D.157.240; 6.D.157.244; 6.D.166.228; 6.D.166.229; 6.D.166.230; 6.D.166.231; 6.D.166.236; 6.D.166.237; 6.D.166.238; 6.D.166.239; 6.D.166.154; 6.D.166.157; 6.D.166.166; 6.D.166.169; 6.D.166.172; 6.D.166.175; 6.D.166.240; 6.D.166.244; 6.D.169.228; 6.D.169.229; 6.D.169.230; 6.D.169.231; 6.D.169.236; 6.D.169.237; 6.D.169.238; 6.D.169.239; 6.D.169.154; 6.D.169.157; 6.D.169.166; 6.D.169.169; 6.D.169.172; 6.D.169.175; 6.D.169.240; 6.D.169.244; 6.D.172.228; 6.D.172.229; 6.D.172.230; 6.D.172.231; 6.D.172.236; 6.D.172.237; 6.D.172.238; 6.D.172.239; 6.D.172.154; 6.D.172.157; 6.D.172.166; 6.D.172.169; 6.D.172.172; 6.D.172.175; 6.D.172.240; 6.D.172.244; 6.D.175.228; 6.D.175.229; 6.D.175.230; 6.D.175.231; 6.D.175.236; 6.D.175.237; 6.D.175.238; 6.D.175.239; 6.D.175.154; 6.D.175.157; 6.D.175.166; 6.D.175.169; 6.D.175.172; 6.D.175.175; 6.D.175.240; 6.D.175.244; 6.D.240.228; 6.D.240.229; 6.D.240.230; 6.D.240.231; 6.D.240.236; 6.D.240.237; 6.D.240.238; 6.D.240.239; 6.D.240.154; 6.D.240.157; 6.D.240.166; 6.D.240.169; 6.D.240.172; 6.D.240.175; 6.D.240.240; 6.D.240.244; 6.D.244.228; 6.D.244.229; 6.D.244.230; 6.D.244.231; 6.D.244.236; 6.D.244.237; 6.D.244.238; 6.D.244.239; 6.D.244.154; 6.D.244.157; 6.D.244.166; 6.D.244.169; 6.D.244.172; 6.D.244.175; 6.D.244.240; 6.D.244.244;

Prodrugs of 6.AB

6.AB.228.228; 6.AB.228.229; 6.AB.228.230; 6.AB.228.231; 6.AB.228.236; 6.AB.228.237; 6.AB.228.238; 6.AB.228.239; 6.AB.228.154; 6.AB.228.157; 6.AB.228.166; 6.AB.228.169; 6.AB.228.172; 6.AB.228.175; 6.AB.228.240; 6.AB.228.244; 6.AB.229.228; 6.AB.229.229; 6.AB.229.230; 6.AB.229.231; 6.AB.229.236; 6.AB.229.237; 6.AB.229.238; 6.AB.229.239; 6.AB.229.154; 6.AB.229.157; 6.AB.229.166; 6.AB.229.169; 6.AB.229.172; 6.AB.229.175; 6.AB.229.240; 6.AB.229.244; 6.AB.230.228; 6.AB.230.229; 6.AB.230.230; 6.AB.230.231; 6.AB.230.236; 6.AB.230.237; 6.AB.230.238; 6.AB.230.239; 6.AB.230.154; 6.AB.23Q.157; 6.AB.230.166; 6.AB.23Q.169; 6.AB.230.172; 6.AB.230.175; 6.AB.230.240; 6.AB.230.244; 6.AB.231.228; 6.AB.231.229; 6.AB.231.230; 6.AB.231.231; 6.AB.231.236; 6.AB.231.237; 6.AB.231.238; 6.AB.231.239; 6.AB.231.154; 6-AB.231.157; 6.AB.231.166; 6.AB.231.169; 6.AB.231.172; 6.AB.231.175; 6.AB.231.240; 6.AB.231.244; 6.AB.236.228; 6.AB.236.229; 6.AB.236.230; 6.AB.236.231; 6.AB.236.236; 6.AB.236.237; 6.AB.236.238; 6.AB.236.239; 6.AB.236.154; 6.AB.236.157; 6.AB.236.166; 6.AB.236.169; 6.AB.236.172; 6.AB.236.175; 6.AB.236.240; 6.AB.236.244; 6.AB.237.228; 6.AB.237.229; 6.AB.237.230; 6.AB.237.231; 6.AB.237.236; 6.AB.237.237; 6.AB.237.238; 6.AB.237.239; 6.AB.237.154; 6.AB.237.157; 6.AB.237.166; 6.AB.237.169; 6.AB.237.172; 6.AB.237.175; 6.AB.237.240; 6.AB.237.244; 6.AB.238.228; 6.AB.238.229; 6.AB.238.230; 6.AB.238.231; 6.AB.238.236; 6.AB.238.237; 6.AB.238.238; 6.AB.238.239; 6.AB.238.154; 6.AB.238.157; 6.AB.238.166; 6.AB.238.169; 6.AB.238.172; 6.AB.238.175; 6.AB.238.240; 6.AB.238.244; 6.AB.239.228; 6.AB.239.229; 6.AB.239.230; 6.AB.239.231; 6.AB.239.236; 6.AB.239.237; 6.AB.239.238; 6.AB.239.239; 6.AB.239.154; 6.AB.239.157; 6.AB.239.166; 6.AB.239.169; 6.AB.239.172; 6.AB.239.175; 6.AB.239.240; 6.AB.239.244; 6.AB.154.228; 6.AB.154.229; 6.AB.154.230; 6.AB.154.231; 6.AB.154.236; 6.AB.154.237; 6.AB.154.238; 6.AB.154.239; 6.AB.154.154; 6.AB.154.157; 6.AB.154.166; 6.AB.154.169; 6.AB.154.172; 6.AB.154.175; 6.AB.154.240; 6.AB.154.244; 6.AB.157.228; 6.AB.157.229; 6.AB.157.230; 6.AB.157.231; 6.AB.157.236; 6.AB.157.237; 6.AB.157.238; 6 AB.157.239; 6.AB.157.154; 6.AB.157.157; 6.AB.157.166; 6.AB.157.169; 6.AB.157.172; 6.AB.157.175; 6.AB.157.240; 6.AB.157.244; 6.AB.166.228; 6.AB.166.229; 6.AB.166.230; 6.AB.166.231; 6.AB.166.236; 6.AB.166.237; 6.AB.166.238; 6.AB.166.239; 6.AB.166.154; 6.AB.166.157; 6.AB.166.166; 6.AB.166.169; 6.AB.166.172; 6.AB.166.175; 6.AB.166.240; 6.AB.166.244; 6.AB.169.228; 6.AB.169.229; 6.AB.169.230; 6.AB.169.231; 6.AB.169.236; 6.AB.169.237; 6.AB.169.238; 6.AB.169.239; 6.AB.169.154; 6.AB.169.157; 6.AB.169.166; 6.AB.169.169; 6.AB.169.172; 6.AB.169.175; 6.AB.169.240; 6.AB.169.244; 6.AB.172.228; 6.AB.172.229; 6.AB.172.230; 6.AB.172.231; 6.AB.172.236; 6.AB.172.237; 6.AB.172.238; 6.AB.172.239; 6.AB.172.154; 6.AB.172.157; 6.AB.172.166; 6.AB.172.169; 6.AB.172.172; 6.AB.172.175; 6.AB.172.24Q; 6.AB.172.244; 6.AB.175.228; 6.AB.175.229; 6.AB.175.230; 6.AB.175.231; 6.AB.175.236; 6.AB.175.237; 6.AB.175.238; 6.AB.175.239; 6.AB.175.154; 6.AB.175.157; 6.AB.175.166; 6.AB.175.169; 6.AB.175.172; 6.AB.175.175; 6.AB.175.240; 6.AB.175.244; 6.AB.240.228; 6.AB.240.229; 6.AB.240.230; 6.AB.240.231; 6.AB.240.236; 6.AB.240.237; 6.AB.240.238; 6.AB.240.239; 6.AB.240.154; 6.AB.240.157; 6.AB.240.166; 6.AB.240.169; 6AB.240.172; 6.AB.24Q.175; 6.AB.24Q.240; 6AB.240.244; 6.AB.244.228; 6 AB.244.229; 6 AB.244.230; 6AB.244.231; 6 AB.244.236; 6AB.244.237; 6 AB.244.238; 6 AB.244.239; 6AB.244.154; 6 AB.244.157; 6AB.244.166; 6AB.244.169; 6AB.244.172; 6AB.244.175; 6AB.244.240; 6AB.244.244;

Prodrugs of 6.BI

6.BI.228.228; 6.BI.228.229; 6.BI.228.230; 6.BI.228.231; 6.BI.228.236; 6.BI.228.237; 6.BI.228.238; 6.BI.228.239; 6-BL228.154; 6.BI.228.157; 6.BI.228.166; 6.BI.228.169; 6.BI.228.172; 6.BI.228.175; 6.BI.228.240; 6.BI.228.244; 6.BI.229.228; 6.BI.229.229; 6.BL229.230; 6.BI.229.231; 6.BI.229.236; 6.BI.229.237; 6.BI.229.238; 6.BI.229.239; 6.BI.229.154; 6.BI.229.157; 6.BL229.166; 6.BI.229.169; 6.BI.229.172; 6.BI.229.175; 6.BI.229.240; 6.BI.229.244; 6.BL230.228; 6.BI.230.229; 6.BI.230.230; 6.BI.230.231; 6.BI.230.236; 6.BI.230.237; 6.BI.230.238; 6.BI.230.239; 6.BI.230.154; 6.BI.230.157; 6.BI.230.166; 6.BI.230.169; 6.BI.230.172; 6.BI.230.175; 6.BI.230.240; 6.BI.230.244; 6.BI.231.228; 6.BI.231.229; 6.BI.231.230; 6.BL231.231; 6.BI.231.236; 6.BI.231.237; 6.BI.231.238; 6.BI.231.239; 6.BI.231.154; 6.BI.231.157; 6.BI.231.166; 6.BI.231.169; 6.BI.231.172; 6.BI.231.175; 6.BI.231.240; 6.BI.231.244; 6.BI.236.228; 6.BI.236.229; 6.BI.236.230; 6.BI.236.231; 6.BI.236.236; 6.BI.236.237; 6.BL236.238; 6.BI.236.239; 6.BI.236.154; 6.BI236.157; 6.BI.236.166; 6.BI.236.169; 6.BI.236.172; 6.BI.236.175; 6.BI.236.240; 6.BI.236.244; 6.BI.237.228; 6.BI.237.229; 6.BI.237.230; 6.BI.237.231; 6.BI.237.236; 6.BI.237.237; 6.BI.237.238; 6.BI.237.239; 6.BI.237.154; 6.BI.237.157; 6.BI.237.166; 6.BI.237.169; 6.BI.237.172; 6.BI.237.175; 6.BI.237.240; 6.BI.237.244; 6.BI.238.228; 6.BI.238.229; 6.BI.238.230; 6.BI.238.231; 6.BI.238.236; 6.BI.238.237; 6.BI.238.238; 6.BI.238.239; 6.BI.238.154; 6.BI.238.157; 6.BI.238.166; 6.BL238.169; 6.BI.238.172; 6.BI.238.175; 6.BI.238.240; 6.BL238.244; 6.BI.239.228; 6.BI.239.229; 6.BI.239.230; 6.BI.239.231; 6.BI.239.236; 6.BI.239.237; 6.BI.239.238; 6.BI.239.239; 6.BI.239.154; 6.BI.239.157; 6.BI.239.166; 6.BI.239.169; 6.BI.239.172; 6.BI.239.175; 6.BI.239.240; 6.BI.239.244; 6.BI.154.228; 6.BI.154.229; 6.BI.154.230; 6.BI.154.231; 6.BI.154.236; 6.BI.154.237; 6.BI.154.238; 6.BI.154.239; 6.BI.154.154; 6.BI.154.157; 6.BI.154.166; 6.BI.154.169; 6.BI.154.172; 6.BI.154.175; 6.BI.154.240; 6.BI.154.244; 6.BI.157.228; 6.BI.157.229; 6.BI.157.230; 6.BI.157.231; 6.BI.157.236; 6.BI.157.237; 6.BI.157.238; 6.BI.157.239; 6.BI.157.154; 6.BI.157.157; 6.BL157.166; 6.BI.157.169; 6.BI.157.172; 6.BI.157.175; 6.BI.157.240; 6.BI.157.244; 6.BI.166.228; 6.BI.166.229; 6.BI.166.230; 6.BI.166.231; 6.BI.166.236; 6.BI.166.237; 6.BI.166.238; 6.BI.166.239; 6.BI.166.154; 6.BI.166.157; 6.BI.166.166; 6.BI.166.169; 6.BI.166.172; 6.BI.166.175; 6.BI.166.240; 6.BI.166.244; 6.BI.169.228; 6.BI.169.229; 6.BI.169.230; 6.BI.169.231; 6.BI.169.236; 6.BI.169.237; 6.BI.169.238; 6.BI.169.239; 6.BI.169.154; 6.BI.169.157; 6.BI.169.166; 6.BI.169.169; 6.BI.169.172; 6.BI.169.175; 6.BI.169.240; 6.BI.169.244; 6.BI.172.228; 6.BI.172.229; 6.BI.172.230; 6.BI.172.231; 6.BI.172.236; 6.BI.172.237; 6.BI.172.238; 6.BI.172.239; 6.BI.172.154; 6.BI.172.157; 6.BI.172.166; 6.BI.172.169; 6.BI.172.172; 6.BI.172.175; 6.BI.172.240; 6.BI.172.244; 6.BI.175.228; 6.BI.175.229; 6.BI.175.230; 6.BI.175.231; 6.BI.175.236; 6.BI.175.237; 6.BI.175.238; 6.BI.175.239; 6.BI.175.154; 6.BI.175.157; 6.BI.175.166; 6.BI.175.169; 6.BI.175.172; 6.BI.175.175; 6.BI.175.240; 6.BI.175.244; 6.BI.240.228; 6.BI.240.229; 6.BI.240.230; 6.BI.240.231; 6.BI.240.236; 6.BI.240.237; 6.BI.240.238; 6.BI.240.239; 6.BI.240.154; 6.BI.240.157; 6.BI.240.166; 6.BI.240.169; 6.BI.240.172; 6.BI.240.175; 6.BI.240.240; 6.BI.240.244; 6.BI.244.228; 6.BI.244.229; 6.BI.244.230; 6.BI.244.231; 6.BI.244.236; 6.BI.244.237; 6.BI.244.238; 6.BI.244.239; 6.BI.244.154; 6.BI.244.157; 6.BI.244.166; 6.BI.244.169; 6.BI.244.172; 6.BI.244.175; 6.BI.244.240; 6.BI.244.244;

Prodrugs of 6.1

6.1.228.228; 6.1.228.229; 6.1.228.230; 6.1.228.231; 6.1.228.236; 6.1.228.237; 6.1.228.238; 6.1.228.239; 6.1.228.154; 6.1.228.157; 6.1.228.166; 6.1.228.169; 6.1.228.172; 6.1.228.175; 6.1.228.240; 6.1.228.244; 6.1.229.228; 6.1.229.229; 6.1.229.230; 6.1.229.231; 6.1.229.236; 6.1.229.237; 6.1.229.238; 6.1.229.239; 6.1.229.154; 6.1.229.157; 6.1.229.166; 6.1.229.169; 6.1.229.172; 6.1.229.175; 6.1.229.240; 6.1.229.244; 6.1.230.228; 6.1.230.229; 6.1.230.230; 6.1.230.231; 6.1.230.236; 6.1.230.237; 6.1.230.238; 6.1.230.239; 6.1.230.154; 6.1.230.157; 6.1.230.166; 6.1.230.169; 6.1.230.172; 6.1.230.175; 6.1.230.240; 6.1.230.244; 6.1.231.228; 6.1.231.229; 6.1.231.230; 6.1.231.231; 6.1.231.236; 6.1.231.237; 6.1.231.238; 6.1.231.239; 6.1.231.154; 6.1.231.157; 6.1.231.166; 6.1.231.169; 6.1.231.172; 6.1.231.175; 6.1.231.240; 6.1.231.244; 6.1.236.228; 6J.236.229; 6.1.236.230; 6.1.236.231; 6.1.236.236; 6.1.236.237; 6.1.236.238; 6.1.236.239; 6.1.236.154; 6.1.236.157; 6.1.236.166; 6.1.236.169; 6.1.236.172; 6.1.236.175; 6.1.236.240; 6.1.236.244; 6.1.237.228; 6.1.237.229; 6.1.237.230; 6.1.237.231; 6.1.237.236; 6.1.237.237; 6.1.237.238; 6.1.237.239; 6.1.237.154; 6.1.237.157; 6.1.237.166; 6.1.237.169; 6.1.237.172; 6.1.237.175; 6.1.237.240; 6.1.237.244; 6.1.238.228; 6.1.238.229; 6.1.238.230; 6.1.238.231; 6.1.238.236; 6.1.238.237; 6.1.238.238; 6.1.238.239; 6.1.238.154; 6.1.238.157; 6.1.238.166; 6.1.238.169; 6.1.238.172; 6.1.238.175; 6.1.238.240; 6.1.238.244; 6.1.239.228; 6.1.239.229; 6.1.239.230; 6.1.239.231; 6.1.239.236; 6.1.239.237; 6.1.239.238; 6.1.239.239; 6.1.239.154; 6.1.239.157; 6.1.239.166; 6.1.239.169; 6.1.239.172; 6.1.239.175; 6.1.239.240; 6.1.239.244; 6.1.154.228; 6.1.154.229; 6.1.154.230; 6.1.154.231; 6.1.154.236; 6.1.154.237; 6.1.154.238; 6.1.154.239; 6.1.154.154; 6.1.154.157; 6.1.154.166; 6.1.154.169; 6.1.154.172; 6.1.154.175; 6.1.154.240; 6.1.154.244; 6.1.157.228; 6.1.157.229; 6.1.157.230; 6.1.157.231; 6.1.157.236; 6.1.157.237; 6.1.157.238; 6.1.157.239; 6.1.157.154; 6.1.157.157; 6.1.157.166; 6.1.157.169; 6.1.157.172; 6.1.157.175; 6.1.157.240; 6.1.157.244; 6.1.166.228; 6.1.166.229; 6.1.166.230; 6.1.166.231; 6.1.166.236; 6.1.166.237; 6.1.166.238; 6.1.166.239; 6.1.166.154; 6.1.166157; 6.1.166.166; 6.1.166.169; 6.1.166.172; 6.1.166.175; 6.1.166.240; 6.1.166.244; 6.1.169.228; 6.1.169.229; 6.1.169.230; 6.1.169.231; 6.1.169.236; 6.1.169.237; 6.1.169.238; 6.1.169.239; 6.1.169.154; 6.1.169.157; 6.1.169.166; 6.1.169.169; 6.1.169.172; 6.1.169.175; 6.1.169.240; 6.1.169.244; 6.1.172.228; 6.1.172.229; 6.1.172.230; 6.1.172.231; 6.1.172.236; 6.1.172.237; 6.1.172.238; 6.1.172.239; 6.1.172.154; 6.1.172.157; 6.1.172.166; 6.1.172.169; 6.1.172.172; 6.1.172.175; 6.1.172.240; 6.1.172.244; 6.1.175.228; 6.1.175.229; 6.1.175.230; 6.1.175.231; 6.1.175.236; 6.1.175.237; 6.1.175.238; 6.1.175.239; 6.1.175.154; 6.1.175.157; 6.1.175.166; 6.1.175.169; 6.1.175.172; 6.1.175.175; 6.1.175.240; 6.1.175.244; 6.1.240.228; 6.1.240.229; 6.1.240.230; 6.1.240.231; 6.1.240.236; 6.1.240.237; 6.1.240.238; 6.1.240.239; 6.1.240.154; 6.1.240.157; 6.1.240.166; 6.1.240.169; 6.1.240.172; 6.1.240.175; 6.1.240.240; 6.1.240.244; 6.1.244.228; 6.1.244.229; 6.1.244.230; 6.1.244.231; 6.1.244.236; 6.1.244.237; 6.1.244.238; 6.1.244.239; 6.1.244.154; 6.1.244.157; 6.1.244.166; 6.1.244.169; 6.1.244.172; 6.1.244.175; 6.1.244.240; 6.1.244.244;

Prodrugs of 6.T

6.J.228.228; 6.J.228.229; 6.J.228.230; 6.J.228.231; 6J.228.236; 6.J.228.237; 6J.228.238; 6J.228.239; 6J.228.154; 6J.228.157; 6J.228.166; 6J.228.169; 6J.228.172; 6J.228.175; 6.J.228.240; 6J.228.244; 6J.229.228; 6J.229.229; 6J.229.230; 6.J.229.231; 6J.229.236; 6J.229.237; 6J.229.238; 6J.229.239; 6.J.229.154; 6J.229.157; 6J.229.166; 6J.229.169; 6J.229.172; 6J.229.175; 6J.229.240; 6J.229.244; 6J.230.228; 6J.230.229; 6J.230.230; 6.J.230.231; 6J.230.236; 6J.230.237; 6J.230.238; 6J.230.239; 6J.230.154; 6J.230.157; 6J.23Q.166; 6J.230.169; 6J.230.172; 6J.230.175; 6J.230.240; 6J.230.244; 6J.231.228; 6J.231.229; 6J.231.230; 6J.231.231; 6J.231.236; 6J.231.237; 6J.231.238; 6J.231.239; 6J.231.154; 6.J.231.157; 6J.231.166; 6J.231.169; 6J.231.172; 6J.231.175; 6J.231.240; 6.J.231.244; 6J.236.228; 6J.236.229; 6J.236.230; 6J.236.231; 6J.236.236; 6J.236.237; 6J.236.238; 6J.236.239; 6J.236.154; 6.J.236.157; 6J.236-166; 6J.236.169; 6J.236.172; 6.J.236.175; 6J.236.240; 6J.236.244; 6J.237.228; 6J.237.229; 6J.237.230; 6J.237.231; 6 J.237.236; 6J.237.237; 6J.237.238; 6 J.237.239; 6J.237.154; 6J.237.157; 6J.237.166; 6.J.237.169; 6J.237.172; 6J.237.175; 6J.237.240; 6J.237.244; 6J.238.228; 6J.238.229; 6J.238.230; 6J.238.231; 6J.238.236; 6 J.238.237; 6 J.238.238; 6J.238.239; 6J.238.154; 6J.238.157; 6J.238.166; 6J.238.169; 6J.238.172; 6J.238.175; 6J.238.240; 6J.238.244; 6 J.239.228; 6J.239.229; 6J.239.230; 6J.239.231; 6 J.239.236; 6J.239.237; 6J.239.238; 6.J.239.239; 6 J.239.154; 6 J.239.157; 6J.239.166; 6.J. ,239.169; 6.J.239.172; 6J.239175; 6J.239.240; 6J.239.244; 6J154.228; 6J154.229; 6J.154.230; 6J154.231; 6J.154.236; 6 J.154.237; 6J154.238; 6J.154.239; 6J154154; 6J154157; 6J154166; 6.J.154.169 ^■; 6J154172; 6J154175; 6.J.154.240; 6J.154.244; 6J157.228; 6J157.229; 6J.157.230; 6J157.231; 6J157.236; 6J157.237; 6J.157.238; 6J157.239; 6 J.157.154; 6J.157.157; 6J.157166; 6J157169; 6J157172; 6.J.157.175; 6J157.240; 6J157.244; 6J.166.228; 6J.166.229; 6J166.230; 6J.166.231; 6J.166.236; 6J166.237; 6J166.238; 6.J166.239; 6J166154; 6J.166.157; 6.J.166.166; 6J166169; 6J.166172; 6.J166.175; 6J.166.240; 6.J.166.244; 6.J.169.228; 6J.169.229; 6.J.169.230; 6J.169.231; 6J.169.236; 6J.169.237; 6J.169.238; 6J.169.239; 6J.169.154; 6J.169.157; 6J.169.166; 6J.169.169; 6J.169.172; 6J.169.175; 6J.169.240; 6J.169.244; 6 J.172.228; 6J.172.229; 6J.172.230; 6J.172.231; 6J.172.236; 6J.172.237; 6J.172.238; 6 J.172.239; 6J.172.154; 6J.172.157; 6J.172.166; 6 J.172.169; 6J.172.172; 6.J.172.175; 6J.172.240; 6J.172.244; 6.J.175.228; 6J.175.229; 6.J.175.230; 6J.175.231; 6J.175.236; 6J.175.237; 6.J.175.238; 6J.175.239; 6J.175.154; 6J.175.157; 6J.175.166; 6J.175.169; 6J.175.172; 6 J.175.175; 6J.175.240; 6J.175.244; 6J.240.228; 6J.240.229; 6J.240.230; 6 J.240.231; 6J.240.236; 6J.240.237; 6J.240.238; 6.J.240.239; 6J.240.154; 6J.240-157; 6 J.240.166; 6J.240.169; 6.J.240.172; 6J.240.175; 6J.240.240; 6J.240.244; 6J.244.228; 6J.244.229; 6J.244.230; 6.J.244.231; 6J.244.236; 6J.244.237; 6J.244.238; 6J.244.239; 6 J.244.154; 6 J.244.157; 6 J.244.166; 6 J.244.169; 6J.244.172; 6J.244.175; 6J.244.240; 6 J.244.244;

Prodrugs of 6.L

6X.228.228; 6.L.228.229; 6.L.228.230; 6.L.228.231; 6.L.228.236; 6.L.228.237; 6.L.228.238; 6.L.228.239; 6X.228.154; 6X.228.157; 6.L.228.166; 6.L.228.169; 6X.228.172; 6X.228.175; 6X.228.240; 6X.228.244; 6X.229.228; 6X.229.229; 6X.229.230; 6X.229.231; 6X.229.236; 6X.229.237; 6X.229.238; 6.L.229.239; 6X.229.154; 6X.229.157; 6X.229.166; 6X.229.169; 6X.229.172; 6X.229.175; 6X.229.240; 6X.229.244; 6X.230.228; 6X.230.229; 6X.230.230; 6X.230.231; 6X.230.236; 6X.230.237; 6X.230.238; 6X.230.239; 6X.230.154; 6X.230.157; 6X.230.166; 6X.230.169; 6X.230.172; 6X.230.175; 6X.230.240; 6X.230.244; 6X.231.228; 6X.231.229; 6X.231.230; 6X.231.231; 6X.231.236; 6X.231.237; 6X.231.238; 6X.231.239; 6X.231.154; 6X.231.157; 6X.231.166; 6X.231.169; 6X.231.172; 6X.231.175; 6X.231.240; 6X.231.244; 6X.236.228; 6X.236.229; 6X.236.230; 6X.236.231; 6X.236.236; 6X.236.237; 6X.236.238; 6X.236.239; 6X.236.154; 6X.236.157; 6X.236.166; 6X.236.169; 6X.236.172; 6X.236.175; 6X.236.240; 6X.236.244; 6X.237.228; 6X.237.229; 6X.237.230; 6X.237.231; 6X.237.236; 6X.237.237; 6X.237.238; 6X.237.239; 6X.237.154; 6X.237.157; 6X.237.166; 6X.237.169; 6X.237.172; 6X.237.175; 6X.237.240; 6X.237.244; 6X.238.228; 6X.238.229; 6X.238.230; 6X.238.231; 6X.238.236; 6X.238.237; 6X.238.238; 6X.238.239; 6X.238.154; 6X.238.157; 6X.238.166; 6X.238.169; 6X.238.172; 6X.238.175; 6X.238.240; 6X.238.244; 6X.239.228; 6X.239.229; 6X.239.230; 6X.239.231; 6X.239.236; 6X.239.237; 6X.239.238; 6X.239.239; 6X.239.154; 6X.239.157; 6X.239.166; 6X.239.169; 6X.239.172; 6X.239.175; 6X.239.240; 6X.239.244; 6X.154.228; 6X.154.229; 6.L.154.230; 6X.154.231; 6X.154.236; 6X.154.237; 6X.154.238; 6X.154.239; 6X.154.154; 6X.154.157; 6X.154.166; 6X.154.169; 6X.154.172; 6X.154.175; 6X.154.240; 6X.154.244; 6X.157.228; 6X.157.229; 6X.157.230; 6X.157.231; 6X.157.236; 6X.157.237; 6X.157.238; 6X.157.239; 6X.157.154; 6X.157.157; 6X.157.166; 6X.157.169; 6X.157.172; 6X.157.175; 6X.157.240; 6X.157.244; 6X.166.228; 6X.166.229; 6X.166.230; 6X.166.231; 6X.166.236; 6X.166.237; 6X.166.238; 6X.166.239; 6X.166.154; 6X.166.157; 6X.166.166; 6X.166.169; 6X.166.172; 6X.166.175; 6X.166.240; 6X.166.244; 6X.169.228; 6X.169.229; 6X.169.230; 6X.169.231; 6X.169.236; 6.L.169.237; 6X.169.238; 6X.169.239; 6X.169.154; 6X.169.157; 6X.169.166; 6X.169.169; 6X.169.172; 6X.169.175; 6X.169.240; 6X.169.244; 6.L.172.228; 6.L.172.229; 6.L.172.230; 6.L.172.231; 6.L.172.236; 6.L.172.237; 6.L.172.238; 6.L.172.239; 6.L.172.154; 6.L.172.157; 6.L.172.166; 6.L.172.169; 6.L.172.172; 6.L.172.175; 6.L.172.240; 6.L.172.244; 6.L.175.228; 6.L.175.229; 6.L.175.230; 6.L.175.231; 6.L.175.236; 6.L.175.237; 6.L.175.238; 6.L.175.239; 6.L.175.154; 6.L.175.157; 6-L.175.166; 6.L.175.169; 6.L.175.172; 6.L.175.175; 6.L.175.240; 6.L.175.244; 6.L.240.228; 6.L.240.229; 6.L.240.230; 6.L.240.231; 6.L.240.236; 6.L.240.237; 6.L.240.238; 6.L.240.239; 6.L.240.154; 6.L.240.157; 6.L.240.166; 6.L.240.169; 6.L.240.172; 6.L.240.175; 6.L.240.240; 6.L.240.244; 6.L.244.228; 6.L.244.229; 6.L.244.230; 6.L.244.231; 6.L.244.236; 6.L.244.237; 6.L.244.238; 6.L.244.239; 6.L.244.154; 6.L.244.157; 6.L.244.166; 6.L.244.169; 6.L.244.172; 6.L.244.175; 6.L.244.240; 6.L.244.244;

Prodrugs of 6.0

6.O.228.228; 6.O.228.229; 6.O.228.230; 6.0.228.231; 6.O.228.236; 6.O.228.237; 6.O.228.238; 6.O.228.239; 6.O.228.154; 6.O.228.157; 6.0-228.166; 6.O.228.169; 6.O.228.172; 6.O.228.175; 6.O.228.240; 6.O.228.244; 6.O.229.228; 6.O.229.229; 6.O.229.230; 6-O-229.231; 6.O.229.236; 6.O.229.237; 6.O.229.238; 6.O.229.239; 6.O.229.154; 6.O.229.157; 6.O.229.166; 6.O.229.169; 6.O.229.172; 6.O.229.175; 6.O.229.240; 6.O.229.244; 6.O.230.228; 6.O.230.229; 6.O.230.230; 6.O.230.231; 6.O.230.236; 6.O.230.237; 6.O.230.238; 6.O.230.239; 6.O.230.154; 6.O.230.157; 6.O.230.166; 6.O.230.169; 6.O.230.172; 6.O.230.175; 6.O.230.240; 6.O.230.244; 6.O.231.228; 6.O.231.229; 6.O.231.230; 6.O.231.231; 6.O.231.236; 6.O.231.237; 6.O.231.238; 6.O.231.239; 6.O.231.154; 6.O.231.157; 6.O.231.166; 6.O.231.169; 6.O.231.172; 6.O.231.175; 6.O.231.240; 6.O.231.244; 6.O.236.228; 6.O.236.229; 6.O.236.230; 6.O.236.231; 6.O.236.236; 6.O.236.237; 6.O.236.238; 6.O.236.239; 6.O.236.154; 6.O-236.157; 6.O-236.166; 6.O.236.169; 6.O.236.172; 6.O.236.175; 6.O.236.240; 6.O.236.244; 6.O.237.228; 6.O.237.229; 6.O.237.230; 6.O.237.231; 6.O.237.236; 6.O.237.237; 6.O.237.238; 6.O.237.239; 6.O.237.154; 6.O.237.157; 6.O.237.166; 6.O.237.169; 6.O.237.172; 6.O.237.175; 6.O.237.240; 6.O.237.244; 6.O.238.228; 6.O.238.229; 6.O.238.230; 6.O.238.231; 6.O.238.236; 6.O.238.237; 6.O.238.238; 6.O.238.239; 6.O.238.154; 6.Q.238.157; 6.O.238.166; 6.O.238.169; 6.O.238.172; 6.O.238.175; 6.O.238.240; 6.O.238.244; 6.O.239.228; 6.O.239.229; 6.O.239.230; 6.O.239.231; 6.O.239.236; 6.O.239.237; 6.O.239.238; 6.O.239.239; 6.O.239.154; 6.O.239.157; 6.O.239.166; 6.O.239.169; 6.O.239.172; 6.O.239.175; 6.O.239.240; 6.O.239.244; 6.O.154.228; 6.O.154.229; 6.O.154.230; 6.O.154.231; 6.O.154.236; 6.O.154.237; 6.O.154.238; 6.O.154.239; 6.O.154.154; 6.O.154.157; 6.O.154.166; 6.O.154.169; 6.O.154.172; 6.O.154.175; 6.O.154.240; 6.O.154.244; 6.O.157.228; 6.O.157.229; 6.O.157.230; 6.O.157.231; 6.O.157.236; 6.O.157.237; 6.O.157.238; 6.O.157.239; 6.O.157.154; 6.O.157.157; 6.O.157.166; 6.O.157.169; 6.O.157.172; 6.O.157.175; 6.O.157.240; 6.O.157.244; 6.O.166.228; 6.O.166.229; 6.O.166.230; 6.O.166.231; 6.O.166.236; 6.O.166.237; 6.O.166.238; 6.O.166.239; 6.O.166.154; 6.O.166.157; 6.O.166.166; 6.O.166.169; 6.O.166.172; 6.O.166.175; 6.O.166.240; 6.O.166.244; 6.O.169.228; 6.O.169.229; 6.O.169.230; 6.O.169.231; 6.O.169.236; 6.O.169.237; 6.O.169.238; 6.O.169.239; 6.O.169.154; 6.O.169.157; 6.O.169.166; 6.O.169.169; 6.O.169.172; 6.O.169.175; 6.O.169.240; 6.O.169.244; 6.O.172.228; 6.O.172.229; 6.O.172.230; 6.O.172.231; 6.O.172.236; 6.O.172.237; 6.O.172.238; 6.O.172.239; 6.O.172.154; 6.O.172.157; 6.O.172.166; 6.O.172.169; 6.O.172.172; 6.O.172.175; 6.O.172.240; 6.O.172.244; 6.O.175.228; 6.O.175.229; 6.O.175.230; 6.O.175.231; 6.O.175.236; 6.O.175.237; 6.O.175.238; 6.O.175.239; 6.O.175.154; 6.O.175.157; 6.O.175.166; 6.O.175.169; 6.O.175.172; 6.O.175.175; 6.O.175.240; 6.O.175.244; 6.O.240.228; 6.O.240.229; 6.O.240.230; 6.O.240.231; 6.O.240.236; 6.O.240.237; 6.O.240.238; 6.O.240.239; 6.O.240.154; 6.Q.240.157; 6.O.240.166; 6.O.240.169; 6.O.240.172; 6.O.240.175; 6.O.240.240; 6.O.240.244; 6.O.244.228; 6.O.244.229; 6.O.244.230; 6.O.244.231; 6.O.244.236; 6.O.244.237; 6.O.244.238; 6.O.244.239; 6.O.244.154; 6.O.244.157; 6.O.244.166; 6.O.244.169; 6.O.244.172; 6.O.244.175; 6.O.244.240; 6.O.244.244;

Prodrugs of 6.P

6.P.228.228; 6.P.228.229; 6.P.228.230; 6.P.228.231; 6.P.228.236; 6.P.228.237; 6.P.228.238; 6.P.228.239; 6.P.228.154; 6.P.228.157; 6.P.228.166; 6.P.228.169; 6.P.228.172; 6.P.228.175; 6.P.228.240; 6.P.228.244; 6.P.229.228; 6.P.229.229; 6.P.229.230; 6.P.229.231; 6.P.229.236; 6.P.229.237; 6.P.229.238; 6.P.229.239; 6.P.229.154; 6.P.229.157; 6.P.229.166; 6.P.229.169; 6.P.229.172; 6.P.229.175; 6.P.229.240; 6.P.229.244; 6.P.230.228; 6.P.230.229; 6.P.230.230; 6.P.230.231; 6.P.230.236; 6.P.230.237; 6.P.230.238; 6.P.230.239; 6.P.230.154; 6.P.230.157; 6.P.230.166; 6.P.230.169; 6.P.230.172; 6.P.230.175; 6.P.230.240; 6.P.230.244; 6.P.231.228; 6.P.231.229; 6.P.231.230; 6.P.231.231; 6.P.231.236; 6.P.231.237; 6.P.231.238; 6.P.231.239; 6.P.231.154; 6.P.231.157; 6-P.231.166; 6.P.231.169; 6.P.231.172; 6.P.231.175; 6.P.231.240; 6.P.231.244; 6.P.236.228; 6.P.236.229; 6.P.236.230; 6.P.236.231; 6.P.236.236; 6.P.236.237; 6.P.236.238; 6.P.236.239; 6.P.236.154; 6.P.236.157; 6.P.236.166; 6.P.236.169; 6.P.236.172; 6.P.236.175; 6.P.236.240; 6.P.236.244; 6.P.237.228; 6.P.237.229; 6.P.237.230; 6.P.237.231; 6.P.237.236; 6.P.237.237; 6.P.237.238; 6.P.237.239; 6.P.237.154; 6.P.237.157; 6.P.237.166; 6.P.237.169; 6.P.237.172; 6.P.237.175; 6.P.237.240; 6.P.237.244; 6.P.238.228; 6.P.238.229; 6.P.238.230; 6.P.238.231; 6.P.238.236; 6.P.238.237; 6.P.238.238; 6.P.238.239; 6.P.238.154; 6.P.238.157; 6.P.238.166; 6.P.238.169; 6.P.238.172; 6.P.238.175; 6.P.238.240; 6.P.238.244; 6.P.239.228; 6-P.239.229; 6.P.239.230; 6.P.239.231; 6.P.239.236; 6.P.239.237; 6.P.239.238; 6.P.239.239; 6.P.239.154; 6.P.239.157; 6.P.239.166; 6.P.239.169; 6.P.239.172; 6.P.239.175; 6.P.239.240; 6.P.239.244; 6.P.154.228; 6.P.154.229; 6.P.154.230; 6.P.154.231; 6.P.154.236; 6.P.154.237; 6.P.154.238; 6.P.154.239; 6.P.154.154; 6.P.154.157; 6.P.154.166; 6.P.154.169; 6.P.154.172; 6.P.154.175; 6.P.154.240; 6.P.154.244; 6.P.157.228; 6.P.157.229; 6.P.157.230; 6.P.157.231; 6.P.157.236; 6.P.157.237; 6.P.157.238; 6.P.157.239; 6.P.157.154; 6.P.157.157; 6.P.157.166; 6.P.157.169; 6.P.157.172; 6.P.157.175; 6.P.157.240; 6.P.157.244; 6.P.166.228; 6.P.166.229; 6.P.166.230; 6.P.166.231; 6.P.166.236; 6.P.166.237; 6.P.166.238; 6.P.166.239; 6.P.166.154; 6.P.166.157; 6.P.166.166; 6.P.166.169; 6.P.166.172; 6.P.166.175; 6.P.166.240; 6.P.166.244; 6.P.169.228; 6.P.169.229; 6.P.169.230; 6.P.169.231; 6.P.169.236; 6.P.169.237; 6.P.169.238; 6.P.169.239; 6.P.169.154; 6.P.169.157; 6.P.169.166; 6.P.169.169; 6.P.169.172; 6.P.169.175; 6.P.169.240; 6.P.169.244; 6.P.172.228; 6.P.172.229; 6.P.172.230; 6.P.172.231; 6.P.172.236; 6.P.172.237; 6.P.172.238; 6.P.172.239; 6.P.172.154; 6.P.172.157; 6.P.172.166; 6.P.172.169; 6.P.172.172; 6.P.172.175; 6.P.172.240; 6.P.172.244; 6.P.175.228; 6.P.175.229; 6.P.175.230; 6.P.175.231; 6.P.175.236; 6.P.175.237; 6.P.175.238; 6.P.175.239; 6.P.175.154; 6.P.175.157; 6.P.175.166; 6.P.175.169; 6.P.175.172; 6.P.175.175; 6.P.175.240; 6.P.175.244; 6.P.240.228; 6.P.240.229; 6.P.240.230; 6.P.240.231; 6.P.240.236; 6.P.240.237; 6.P.240.238; 6.P.240.239; 6.P.240.154; 6.P.240.157; 6.P.240.166; 6.P.240.169; 6.P.240.172; 6.P.240.175; 6.P.240.240; 6.P.240.244; 6.P.244.228; 6.P.244.229; 6.P.244.230; 6.P.244.231; 6.P.244.236; 6.P.244.237; 6.P.244.238; 6.P.244.239; 6.P.244.154; 6.P.244.157; 6.P.244.166; 6.P.244.169; 6.P.244.172; 6.P.244.175; 6.P.244.240; 6.P.244.244;

Prodrugs of 6.U

6.U.228.228; 6.U.228.229; 6.U.228.230; 6.U.228.231; 6.U.228.236; 6.U.228.237; 6.U.228.238; 6.U.228.239; 6.U.228.154; 6.U.228.157; 6.U.228.166; 6.U.228.169; 6.U.228.172; 6.U.228.175; 6.U.228.240; 6.U.228.244; 6.U.229.228; 6.U.229.229; 6.U.229.230; 6.U.229.231; 6.U.229.236; 6.U.229.237; 6.U.229.238; 6.U.229.239; 6.U.229.154; 6.U.229.157; 6.U.229.166; 6.U.229.169; 6.U.229.172; 6.U.229.175; 6.U.229.240; 6.U.229.244; 6.U.230.228; 6.U.230.229; 6.U.230.230; 6.U.230.231; 6.U.230.236; 6.U.230.237; 6.U.230.238; 6.U.230.239; 6.U.230.154; 6.U.230.157; 6.U.230.166; 6.U.230.169; 6.U.230.172; 6.U.230.175; 6.U.230.240; 6.U.230.244; 6.U.231.228; 6.U.231.229; 6.U.231.230; 6.U.231.231; 6.U.231.236; 6.U.231.237; 6.U.231.238; 6.U.231.239; 6.U.231.154; 6.U.231.157; 6.U.231.166; 6.U.231.169; 6.U.231.172; 6.U.231.175; 6.U.231.240; 6.U.231.244; 6.U.236.228; 6.U.236.229; 6.U.236.230; 6.U.236.231; 6.U.236.236; 6.U.236.237; 6.U.236.238; 6.U.236.239; 6.U.236.154; 6.U.236.157; 6.U.236.166; 6.U.236.169; 6.U.236.172; 6.U.236.175; 6.U.236.240; 6.U.236.244; 6.U.237.228; 6.U.237.229; 6.U.237.230; 6.U.237.231; 6.U.237.236; 6.U.237.237; 6.U.237.238; 6.U.237.239; 6.U.237.154; 6.U.237.157; 6.U.237.166; 6.U.237.169; 6.U.237.172; 6.U.237.175; 6.U.237.240; 6.U.237.244; 6.U.238.228; 6.U.238.229; 6.U.238.230; 6.U.238.231; 6.U.238.236; 6.U.238.237; 6.U.238.238; 6.U.238.239; 6.U.238.154; 6.U.238.157; 6.U.238.166; 6.U.238.169; 6.U.238.172; 6.U.238.175; 6.U.238.240; 6.U.238.244; 6.U.239.228; 6.U.239.229; 6.U.239.230; 6.U.239.231; 6.U.239.236; 6.U.239.237; 6.U.239.238; 6.U.239.239; 6.U.239.154; 6.U.239.157; 6.U.239.166; 6.U.239.169; 6.U.239.172; 6.U.239.175; 6.U.239.240; 6.U.239.244; 6.U.154.228; 6.U.154.229; 6.U.154.230; 6.U.154.231; 6.U.154.236; 6.U.154.237; 6.U.154.238; 6.U.154.239; 6.U.154.154; 6.U.154.157; 6.U.154.166; 6.U.154.169; 6.U.154.172; 6.U.154.175; 6.U.154.240; 6.U.154.244; 6.U.157.228; 6.U.157.229; 6.U.157.230; 6.U.157.231; 6.U.157.236; 6.U.157.237; 6.U.157.238; 6.U.157.239; 6.U.157.154; 6.U.157.157; 6.U.157.166; 6.U.157.169; 6.U.157.172; 6.U.157.175; 6.U.157.240; 6.U.157.244; 6.U.166.228; 6.U.166.229; 6.U.166.230; 6.U.166.231; 6.U.166.236; 6.U.166.237; 6.U.166.238; 6.U.166.239; 6.U.166.154; 6.U.166.157; 6.U.166.166; 6.U.166.169; 6.U.166.172; 6.U.166.175; 6.U.166.240; 6.U.166.244; 6.U.169.228; 6.U.169.229; 6.U.169.230; 6.U.169.231; 6.U.169.236; 6.U.169.237; 6.U.169.238; 6.U.169.239; 6.U.169.154; 6.U.169.157; 6.U.169.166; 6.U.169.169; 6.U.169.172; 6.U.169.175; 6.U.169.240; 6.U.169.244; 6.U.172.228; 6.U.172.229; 6.U.172.230; 6.U.172.231; 6.U.172.236; 6.U.172.237; 6.U.172.238; 6.U.172.239; 6.U.172.154; 6.U.172.157; 6.U.172.166; 6.U.172.169; 6.U.172.172; 6.U.172.175; 6.U.172.240; 6.U.172.244; 6.U.175.228; 6.U.175.229; 6.U.175.230; 6.U.175.231; 6.U.175.236; 6.U.175.237; 6.U.175.238; 6.U..175..239; 6.U.175.154; 6.U.175.157; 6.U.175.166; 6.U.175.169; 6.U.175.172; 6.U.175.175; 6.U.175.240; 6.U.175.244; 6.U.240.228; 6.U.240.229; 6.U.240.230; 6.U.240.231; 6.U.240.236; 6.U.240.237; 6.U.240.238; 6.U.240.239; 6.U.240.154; 6.U.240.157; 6.U.240.166; 6.U.240.169; 6.U.240.172; 6.U.240.175; 6.U.240.240; 6.U.240.244; 6.U.244.228; 6.U.244.229; 6.U.244.230; 6.U.244.231; 6.U.244.236; 6.U.244.237; 6.U.244.238; 6.U.244.239; 6.U.244.154; 6.U.244.157; 6.U.244.166; 6.U.244.169; 6.U.244.172; 6.U.244.175; 6.U.244.240; 6.U.244.244;

Prodrugs of 6.CD

6.CD.228.228; 6.CD.228.229; 6.CD.228.230; 6.CD.228.231; 6.CD.228.236; 6.CD.228.237; 6.CD.228.238; 6.CD.228.239; 6.CD.228.154; 6.CD.228.157; 6.CD.228.166; 6.CD.228.169; 6. CD.228.172; 6.CD.228.175; 6.CD.228.240; 6.CD.228.244; 6.CD.229.228; 6.CD.229.229; 6.CD.229.230; 6.CD.229.231; 6.CD.229.236; 6.CD.229.237; 6.CD.229.238; 6.CD.229.239; 6.CD.229.154; 6.CD.229.157; 6-CD.229.166; 6.CD.229.169; 6.CD.229.172; 6.CD.229.175; 6.CD.229.240; 6.CD.229.244; 6.CD.230.228; 6.CD.230.229; 6.CD.230.230; 6.CD.230.231; 6.CD.230.236; 6.CD.230.237; 6.CD.230.238; 6.CD.230.239; 6.CD.230.154; 6.CD.230.157; 6.CD.230.166; 6.CD.230.169; 6.CD.230.172; 6.CD.230.175; 6.CD.230.240; 6.CD.230.244; 6.CD.231.228; 6.CD.231.229; 6.CD.231.230; 6.CD.231.231; 6.CD.231.236; 6. ,CD..231..237; 6.CD.231.238; 6.CD.231.239; 6.CD.231.154; 6.CD.231.157; 6.CD.231.166; 6. CD. ,231.169; 6.CD.231.172; 6.CD.231.175; 6.CD.231.240; 6.CD.231.244; 6.CD.236.228; 6.CD.236.229; 6.CD.236.230; 6.CD.236.231; 6.CD.236.236; 6.CD.236.237; 6.CD.236.238; 6.CD.236.239; 6.CD.236.154; 6.CD.236.157; 6.CD.236.166; 6.CD.236.169; 6. CD. ,236.172; 6. CD. ,236.175; 6.CD.236.240; 6.CD.236.244; 6.CD.237.228; 6.CD.237.229; 6.CD.237.230; 6.CD.237.231; 6.CD.237.236; 6.CD.237.237; 6.CD.237.238; 6.CD-237.239; 6.CD.237.154; 6.CD.237.157; 6.CD.237.166; 6.CD.237.169; 6.CD.237.172; 6.CD.237.175; 6.CD.237.240; 6.CD.237.244; 6.CD.238.228; 6.CD.238.229; 6.CD.238.230; 6.CD.238.231; 6.CD.238.236; 6.CD.238.237; 6.CD.238.238; 6.CD.238.239; 6.CD.238.154; 6.CD.238.157; 6.CD.238.166; 6.CD.238.169; 6.CD.238.172; 6.CD.238.175; 6.CD.238.240; 6.CD.238.244; 6.CD.239.228; 6.CD.239.229; 6.CD.239.230; 6.CD.239.231; 6.CD.239.236; 6.CD.239.237; 6.CD.239.238; 6.CD.239.239; 6.CD.239.154; 6.CD.239.157; 6. CD. ,239.166; 6.CD.239.169; 6.CD.239.172; 6.CD.239.175; 6.CD.239.240; 6.CD.239.244; 6.CD.154.228; 6.CD.154.229; 6.CD.154.230; 6.CD.154.231; 6.CD.154.236; 6.CD.154.237; 6.CD.154.238; 6.CD.154.239; 6.CD.154.154; 6.CD.154.157; 6.CD.154.166; 6.CD.154.169; 6.CD.154.172; 6.CD.154.175; 6.CD.154.240; 6.CD.154.244; 6.CD.157.228; 6.CD.157.229; 6.CD.157.230; 6.CD.157.231; 6.CD.157.236; 6.CD.157.237; 6.CD.157.238; 6.CD.157.239; 6.CD.157.154; 6.CD.157.157; 6.CD.157.166; 6.CD.157.169; 6.CD.157.172; 6.CD.157.175; 6.CD.157.240; 6.CD.157.244; 6.CD.166.228; 6.CD.166.229; 6.CD.166.230; 6.CD.166.231; 6.CD.166.236; 6.CD.166.237; 6.CD.166.238; 6.CD.166.239; 6.CD.166.154; 6.CD.166.157; 6.CD.166.166; 6.CD.166.169; 6.CD.166.172; 6.CD.166.175; 6.CD.166.240; 6.CD.166.244; 6.CD.169.228; 6. CD.169.229; 6.CD.169.230; 6.CD.169.231; 6.CD.169.236; 6.CD.169.237; 6.CD.169.238; 6.CD.169.239; 6.CD.169.154; 6.CD.169.157; 6.CD.169.166; 6.CD.169.169; 6.CD.169.172; 6.CD.169.175; 6.CD.169.240; 6.CD.169.244; 6.CD.172.228; 6.CD.172.229; 6.CD.172.230; 6.CD.172.231; 6.CD.172.236; 6.CD.172.237; 6.CD.172.238; 6.CD.172.239; 6.CD.172.154; 6.CD.172.157; 6.CD.172.166; 6.CD.172.169; 6.CD.172.172; 6.CD.172.175; 6.CD.172.240; 6.CD.172.244; 6.CD.175.228; 6.CD.175.229; 6.CD.175.230; 6.CD.175.231; 6.CD.175.236; 6.CD.175.237; 6.CD.175.238; 6.CD.175.239; 6.CD.175.154; 6.CD.175.157; 6.CD.175.166; 6.CD.175.169; 6.CD.175.172; 6.CD.175.175; 6.CD.175.240; 6.CD.175.244; 6.CD.240.228; 6.CD.240.229; 6.CD.240.230; 6.CD.240.231; 6.CD.240.236; 6.CD.240.237; 6.CD.240.238; 6.CD.240.239; 6.CD.240.154; 6.CD.240.157; 6.CD.240.166; 6.CD.240.169; 6.CD.240.172; 6.CD.240.175; 6.CD.240.240; 6.CD.240.244; 6.CD.244.228; 6.CD.244.229; 6.CD.244.23Q; 6.CD.244.231; 6.CD.244.236; 6.CD.244.237; 6.CD.244.238; 6.CD.244.239; 6.CD.244.154; 6.CD.244.157; 6.CD.244.166; 6.CD.244.169; 6.CD.244.172; 6.CD.244.175; 6.CD.244.240; 6.CD.244.244;

Prodrugs of 6.EB

6.EB.228.228; 6.EB.228.229; 6.EB.228.230; 6.EB.228.231; 6.EB.228.236; 6.EB.228.237; 6.EB.228.238; 6.EB.228.239; 6.EB.228.154; 6.EB.228.157; 6.EB.228.166; 6.EB.228.169; 6.EB.228.172; 6.EB.228.175; 6.EB.228.240; 6.EB.228.244; 6.EB.229.228; 6.EB.229.229; 6.EB.229.230; 6.EB.229.231; 6.EB.229.236; 6.EB.229.237; 6.EB.229.238; 6.EB.229.239; 6.EB.229.154; 6.EB.229.157; 6.EB.229.166; 6.EB.229.169; 6.EB.229.172; 6.EB.229.175; 6.EB.229.240; 6.EB.229.244; 6.EB.230.228; 6.EB.230.229; 6.EB.230.230; 6.EB.230.231; 6.EB.230.236; 6.EB.230.237; 6.EB.230.238; 6.EB.230.239; 6.EB.230.154; 6.EB.230.157; 6.EB.230.166; 6.EB.230.169; 6.EB.230.172; 6.EB.230.175; 6.EB.230.240; 6.EB.23Q.244; 6.EB.231.228; 6.EB.231.229; 6.EB.231.230; 6.EB.231.231; 6.EB.231.236; 6.EB.231.237; 6.EB.231.238; 6.EB.231.239; 6.EB.231.154; 6.EB.231.157; 6.EB.231.166; 6.EB.231.169; 6.EB.231.172; 6.EB.231.175; 6.EB.231.240; 6.EB.231.244; 6.EB.236.228; 6.EB.236.229; 6.EB.236.230; 6-EB.236.231; 6.EB.236.236; 6.EB.236.237; 6.EB.236.238; 6.EB.236.239; 6.EB.236.154; 6.EB.236.157; 6.EB.236.166; 6.EB.236.169; 6.EB.236.172; 6.EB.236.175; 6.EB.236.24Q; 6.EB.236.244; 6.EB.237.228; 6.EB.237.229; 6.EB.237.230; 6.EB.237.231; 6.EB.237.236; 6.EB.237.237; 6.EB.237.238; 6.EB.237.239; 6.EB.237.154; 6.EB.237.157; 6.EB.237.166; 6.EB.237.169; 6.EB.237.172; 6.EB.237.175; 6.EB.237.240; 6.EB.237.244; 6.EB.238.228; 6.EB.238.229; 6.EB.238.230; 6.EB.238.231; 6.EB.238.236; 6.EB.238.237; 6.EB.238.238; 6.EB.238.239; 6.EB.238.154; 6.EB.238.157; 6.EB.238.166; 6.EB.238.169; 6.EB.238.172; 6.EB.238.175; 6.EB.238.240; 6.EB.238.244; 6.EB.239.228; 6.EB.239.229; 6.EB.239.230; 6.EB.239.231; 6.EB.239.236; 6.EB.239.237; 6.EB.239.238; 6.EB.239.239; 6.EB.239.154; 6.EB.239.157; 6.EB.239.166; 6.EB.239.169; 6.EB.239.172; 6.EB.239.175; 6.EB.239.240; 6.EB.239.244; 6.EB.154.228; 6.EB.154.229; 6.EB.154.230; 6.EB.154.231; 6.EB.154.236; 6.EB.154.237; 6.EB.154.238; 6.EB.154.239; 6.EB.154.154; 6.EB.154.157; 6.EB.154.166; 6.EB.154.169; 6.EB.154.172; 6.EB.154.175; 6.EB.154.240; 6.EB.154.244; 6.EB.157.228; 6.EB.157.229; 6.EB.157.230; 6.EB.157.231; 6.EB.157.236; 6.EB.157.237; 6.EB.157.238; 6.EB.157.239; 6.EB.157.154; 6.EB.157.157; 6.EB.157.166; 6.EB.157.169; 6.EB.157.172; 6.EB.157.175; 6.EB.157.240; 6.EB.157.244; 6.EB.166.228; 6.EB.166.229; 6.EB.166.230; 6.EB.166.231; 6.EB.166.236; 6.EB.166.237; 6.EB.166.238; 6.EB.166.239; 6.EB.166.154; 6.EB.166.157; 6.EB.166.166; 6.EB.166.169; 6.EB.166.172; 6.EB.166.175; 6.EB.166.240; 6.EB.166.244; 6.EB.169.228; 6.EB.169.229; 6.EB.169.230; 6.EB.169.231; 6.EB.169.236; 6.EB.169.237; 6.EB.169.238; 6.EB.169.239; 6.EB.169.154; 6.EB.169.157; 6.EB.169.166; 6.EB.169.169; 6.EB.169.172; 6.EB.169.175; 6.EB.169.240; 6.EB.169.244; 6.EB.172.228; 6.EB.172.229; 6.EB.172.230; 6.EB.172.231; 6.EB.172.236; 6.EB.172.237; 6.EB.172.238; 6.EB.172.239; 6.EB.172.154; 6.EB.172.157; 6.EB.172.166; 6.EB.172.169; 6.EB.172.172; 6.EB.172.175; 6.EB.172.240; 6.EB.172.244; 6.EB.175.228; 6.EB.175.229; 6.EB.175.230; 6.EB.175.231; 6.EB.175.236; 6.EB.175.237; 6.EB.175.238; 6.EB.175.239; 6.EB.175.154; 6.EB.175.157; 6.EB.175.166; 6.EB.175.169; 6.EB.175.172; 6.EB.175.175; 6.EB.175.240; 6.EB.175.244; 6.EB.240.228; 6.EB.240.229; 6.EB.240.230; 6.EB.240.231; 6.EB.240.236; 6.EB.240.237; 6.EB.240.238; 6.EB.240.239; 6.EB.240.154; 6.EB.240.157; 6.EB.240.166; 6.EB.240.169; 6.EB.240.172; 6.EB.240.175; 6.EB.240.240; 6.EB.240.244; 6.EB.244.228; 6.EB.244.229; 6.EB.244.230; 6.EB.244.231; 6.EB.244.236; 6.EB.244.237; 6.EB.244.238; 6.EB.244.239; 6.EB.244.154; 6.EB.244.157; 6.EB.244.166; 6.EB.244.169; 6.EB.244.172; 6.EB.244.175; 6.EB.244.240; 6.EB.244.244;

Prodrugs of 7.B

7.B.228.228; 7.B.228.229; 7.B.228.230; 7.B.228.231; 7.B.228.236; 7.B.228.237; 7.B.228.238; 7.B.228.239; 7.B.228.154; 7.B.228.157; 7.B.228.166; 7.B.228.169; 7.B.228.172; 7.B.228.175; 7.B.228.240; 7.B.228.244; 7.B.229.228; 7.B.229.229; 7.B.229.230; 7.B.229.231; 7.B.229.236; 7.B.229.237; 7.B.229.238; 7.B.229.239; 7.B.229.154; 7.B.229.157; 7.B.229.166; 7.B.229.169; 7.B.229.172; 7.B.229.175; 7.B.229.240; 7.B.229.244; 7.B.230.228; 7.B.230.229; 7.B.230.230; 7.B.230.231; 7.B.230.236; 7.B.230.237; 7.B.230.238; 7.B.230-239; 7.B.230.154; 7.B.230.157; 7.B.230.166; 7.B.230.169; 7.B.230.172; 7.B.230.175; 7.B.230.240; 7.B.230.244; 7.B.231.228; 7.B.231.229; 7.B.231.23Q; 7.B.231.231; 7.B.231.236; 7.B.231.237; 7.B.231.238; 7.B.231.239; 7.B.231.154; 7.B.231.157; 7.B.231.166; 7.B.231.169; 7.B.231.172; 7.B.231.175; 7.B.231.240; 7.B.231.244; 7.B.236.228; 7.B.236.229; 7.B.236.230; 7.B.236.231; 7.B.236.236; 7.B.236.237; 7.B.236.238; 7.B.236.239; 7.B.236.154; 7.B.236.157; 7.B.236.166; 7.B.236.169; 7.B.236.172; 7.B.236.175; 7.B.236.240; 7.B.236.244; 7.B.237.228; 7.B.237.229; 7.B.237.230; 7.B.237.231; 7.B.237.236; 7.B.237.237; 7.B.237.238; 7.B.237.239; 7.B.237.154; 7.B.237.157; 7.B.237.166; 7.B.237.169; 7.B.237.172; 7.B.237.175; 7.B.237.240; 7.B.237.244; 7.B.238.228; 7.B.238.229; 7.B.238.230; 7.B.238.231; 7.B.238.236; 7.B.238.237; 7.B.238.238; 7.B.238.239; 7.B.238.154; 7.B.238.157; 7.B.238.166; 7.B.238.169; 7.B.238.172; 7.B.238.175; 7.B.238.240; 7.B.238.244; 7.B.239.228; 7.B.239.229; 7.B.239.230; 7.B.239.231; 7.B.239.236; 7.B.239.237; 7.B.239.238; 7.B.239.239; 7.B.239.154; 7.B.239.157; 7.B.239.166; 7.B.239.169; 7.B.239.172; 7.B.239.175; 7.B.239.240; 7.B.239.244; 7.B.154.228; 7.B.154.229; 7.B.154.230; 7.B.154.231; 7.B.154.236; 7.B.154.237; 7.B.154.238; 7.B.154.239; 7.B.154.154; 7.B.154.157; 7.B.154.166; 7.B.154.169; 7.B.154.172; 7.B.154.175; 7.B.154.240; 7.B.154.244; 7.B.157.228; 7.B.157.229; 7.B.157.230; 7.B.157.231; 7.B.157.236; 7.B.157.237; 7.B.157.238; 7.B.157.239; 73.157.154; 73.157.157; 73.157.166; 7.B.157.169; 7.B.157.172; 7.B.157.175; 7.B.157.240; 7.B.157.244; 7.B.166.228; 7.B.166.229; 7.B.166.230; 7.B.166.231; 7.B.166.236; 7.B.166.237; 7.B.166.238; 7.B.166.239; 7.B.166.154; 7.B.166.157; 7.B.166.166; 7.B.166.169; 7.B.166.172; 73.166.175; 7.B.166.240; 7.B.166.244; 7.B.169.228; 7.B.169.229; 7.B.169.230; 7.B.169.231; 7.B.169.236; 7.B.169.237; 7.B.169.238; 7.B.169.239; 7.B.169.154; 7.B.169.157; 7.B.169.166; 7.B.169.169; 7.B.169.172; 7.B.169.175; 7.B.169.240; 7.B.169.244; 7.B.172.228; 7.B.172.229; 7.B.172.230; 7.B.172.231; 7.B.172.236; 7.B.172.237; 7.B.172.238; 7.B.172.239; 7.B.172.154; 7.B.172.157; 7.B.172.166; 7.B.172.169; 7.B.172.172; 7.B.172.175; 7.B.172.240; 7.B.172.244; 7.B.175.228; 7.B.175.229; 7.B.175.230; 7.B.175.231; 7.B.175.236; 7.B.175.237; 7.B.175.238; 7.B.175.239; 7.B.175.154; 7.B.175.157; 73.175.166; 73.175.169; 73.175.172; 73.175.175; 7.B.175.240; 73.175.2U; 7.B.240.228; 7.B.240.229; 7.B.240.230; 7.B.240.231; 7.B.240.236; 7.B.24Q.237; 7.B.240.238; 7.B.240.239; 7.B.240.154; 7.B.240.157; 7.B.240.166; 7.B.240.169; 7.B.240.172; 7.B.240.175; 7.B.240.240; 7.B.240.244; 7.B.244.228; 7.B.244.229; 7.B.244.230; 7.B.244.231; 73.2U.236; 73.2U.237; 7.B.244.238; 7.B.244.239; 7.B.244.154; 7.B.244.157; 73.2U.166; 7.B.244.169; 7.B.244.172; 7.B.244.175; 73.2U.240; 73.2U.2U;

Prodrugs of 7.D

7.D.228.228; 7.D.228.229; 7.D.228.230; 7.D.228.231; 7.D.228.236; 7.D.228.237; 7.D.228.238; 7.D.228.239; 7.D.228.154; 7.D.228.157; 7.D.228.166; 7.D.228.169; 7.D.228.172; 7.D.228.175; 7.D.228.240; 7.D.228.244; 7.D.229.228; 7.D.229.229; 7.D.229.230; 7.D.229.231; 7.D.229.236; 7.D.229.237; 7.D.229.238; 7.D.229.239; 7.D.229.154; 7.D.229.157; 7.D.229.166; 7.D.229.169; 7.D.229.172; 7.D.229.175; 7.D.229.240; 7.D.229.244; 7.D.230.228; 7.D.230.229; 7.D.230.230; 7.D.230.231; 7.D.230.236; 7.D.230.237; 7.D.230.238; 7.D.230.239; 7.D.230.154; 7.D.230.157; 7.D.230.166; 7.D.230.169; 7.D.230.172; 7.D.230.175; 7.D.230.240; 7.D.230.244; 7.D.231.228; 7.D.231.229; 7.D.231.230; 7.D.231.231; 7.D.231.236; 7.D.231.237; 7.D.231.238; 7.D.231.239; 7.D.231.154; 7.D.231.157; 7.D.231.166; 7.D.231.169; 7.D.231.172; 7.D.231.175; 7.D.231.240; 7.D.231.244; 7.D.236.228; 7.D.236.229; 7.D.236.230; 7.D.236.231; 7.D.236.236; 7.D.236.237; 7.D.236.238; 7.D.236.239; 7.D.236.154; 7.D.236.157; 7.D.236.166; 7.D.236.169; 7.D.236.172; 7.D.236.175; 7.D.236.240; 7.D.236.244; 7.D.237.228; 7.D.237.229; 7.D.237.230; 7.D.237.231; 7.D.237.236; 7.D.237.237; 7.D.237.238; 7.D.237.239; 7.D.237.154; 7.D.237.157; 7.D.237.166; 7.D.237.169; 7.D.237.172; 7.D.237.175; 7.D.237.240; 7.D.237.244; 7.D.238.228; 7.D.238.229; 7.D.238.230; 7.D.238.231; 7.D.238.236; 7.D.238.237; 7.D.238.238; 7.D.238.239; 7.D.238.154; 7.D.238.157; 7.D.238.166; 7.D.238.169; 7.D.238.172; 7.D.238.175; 7.D.238.240; 7.D.238.244; 7.D.239.228; 7.D.239.229; 7.D.239.230; 7.D.239.231; 7.D.239.236; 7.D.239.237; 7.D.239.238; 7.D.239.239; 7.D.239.154; 7.D.239.157; 7.D.239.166; 7.D.239.169; 7.D.239.172; 7.D.239.175; 7.D.239.240; 7.D.239.244; 7.D.154.228; 7.D.154.229; 7.D.154.230; 7.D.154.231; 7.D.154.236; 7.D.154.237; 7.D.154.238; 7.D.154.239; 7.D.154.154; 7.D.154.157; 7.D.154.166; 7.D.154.169; 7.D.154.172; 7.D.154.175; 7.D.154.240; 7.D.154.244; 7.D.157.228; 7.D.157.229; 7.D.157.230; 7.D.157.231; 7.D.157.236; 7.D.157.237; 7.D.157.238; 7.D.157.239; 7.D.157.154; 7.D.157.157; 7.D.157.166; 7.D.157.169; 7.D.157.172; 7.D.157.175; 7.D.157.240; 7.D.157.244; 7.D.166.228; 7.D.166.229; 7.D.166.230; 7.D.166.231; 7.D.166.236; 7.D.166.237; 7.D.166.238; 7.D.166.239; 7.D.166.154; 7.D.166.157; 7.D.166.166; 7.D.166.169; 7.D.166.172; 7.D.166.175; 7.D.166.240; 7.D.166.244; 7.D.169.228; 7.D.169.229; 7.D.169.230; 7.D.169.231; 7.D.169.236; 7.D.169.237; 7.D.169.238; 7.D.169.239; 7.D.169.154; 7.D.169.157; 7.D.169.166; 7.D.169.169; 7.D.169.172; 7.D.169.175; 7.D.169.240; 7.D.169.244; 7.D.172.228; 7.D.172.229; 7.D.172.230; 7.D.172.231; 7.D.172.236; 7.D.172.237; 7.D.172.238; 7.D.172.239; 7.D.172.154; 7.D.172.157; 7.D.172.166; 7.D.172.169; 7.D.172.172; 7.D.172.175; 7.D.172.240; 7.D.172.244; 7.D.175.228; 7.D.175.229; 7.D.175.230; 7.D.175.231; 7.D.175.236; 7.D.175.237; 7.D.175.238; 7.D.175.239; 7.D.175.154; 7.D.175.157; 7.D.175.166; 7.D.175.169; 7.D.175.172; 7.D.175.175; 7.D.175.240; 7.D.175.244; 7.D.240.228; 7.D.240.229; 7.D.240.230; 7.D.240.231; 7.D.240.236; 7.D.240.237; 7.D.240.238; 7.D.240.239; 7.D.240.154; 7.D.240.157; 7.P.240.166; 7.D.240.169; 7.D.240.172; 7.D.240.175; 7.D.240.240; 7.D.240.244; 7.D.244.228; 7.D.244.229; 7.D.244.230; 7.D.244.231; 7.D.244.236; 7.D.244.237; 7.D.244.238; 7.D.244.239; 7.D.244.154; 7.D.244.157; 7.D.244.166; 7.D.244.169; 7.D.244.172; 7.D.244.175; 7.D.244.240; 7.D.244.244;

Prodrugs of 7.AB

7.AB.228.228; 7.AB.228.229; 7.AB.228.230; 7.AB.228.231; 7.AB.228.236; 7.AB.228.237; 7.AB.228.238; 7.AB.228.239; 7.AB.228.154; 7.AB.228.157; 7.AB.228.166; 7.AB.228.169; 7.AB.228.172; 7.AB.228.175; 7.AB.228.240; 7.AB.228.244; 7.AB.229.228; 7.AB.229.229; 7.AB.229.230; 7.AB.229.231; 7.AB.229.236; 7.AB.229.237; 7.AB.229.238; 7.AB.229.239; 7.AB.229.154; 7.AB.229.157; 7.AB.229.166; 7.AB.229.169; 7.AB.229.172; 7.AB.229.175; 7.AB.229.240; 7.AB.229.244; 7.AB.230.228; 7.AB.230.229; 7.AB.23Q.230; 7.AB.230.231; 7.AB.230.236; 7.AB.230.237; 7.AB.230.238; 7.AB.230.239; 7.AB.230.154; 7.AB.230.157; 7.AB.230.166; 7.AB.230.169; 7.AB.23Q.172; 7.AB.230.175; 7.AB.230.240; 7.AB.230.244; 7.AB.231.228; 7.AB.231.229; 7.AB.231.230; 7.AB.231.231; 7.AB.231.236; 7.AB.231.237; 7.AB.231.238; 7.AB.231.239; 7.AB.231.154; 7.AB.231.157; 7.AB.231.166; 7.AB.231.169; 7.AB.231.172; 7.AB.231.175; 7.AB.231.240; 7.AB.231.244; 7.AB.236.228; 7.AB.236.229; 7.AB.236.230; 7.AB.236.231; 7.AB.236.236; 7.AB.236.237; 7.AB.236.238; 7.AB.236.239; 7.AB.236.154; 7.AB.236.157; 7.AB.236.166; 7.AB.236.169; 7.AB.236.172; 7.AB.236.175; 7.AB.236.240; 7.AB.236.244; 7.AB.237.228; 7.AB.237.229; 7.AB.237.230; 7.AB.237.231; 7.AB.237.236; 7.AB.237.237; 7.AB.237.238; 7.AB.237.239; 7.AB.237.154; 7.AB.237.157; 7.AB.237.166; 7.AB.237.169; 7.AB.237.172; 7.AB.237.175; 7.AB.237.240; 7.AB.237.244; 7.AB.238.228; 7.AB.238.229; 7.AB.238.230; 7.AB.238.231; 7.AB.238.236; 7AB.238.237; 7.AB.238.238; 7.AB.238.239; 7.AB.238.154; 7.AB.238.157; 7.AB.238.166; 7.AB.238.169; 7.AB.238.172; 7.AB.238.175; 7.AB.238.240; 7.AB.238.244; 7.AB.239.228; 7.AB.239.229; 7.AB.239.230; 7.AB.239.231; 7.AB.239.236; 7.AB.239.237; 7.AB.239.238; 7.AB.239.239; 7.AB.239.154; 7AB.239.157; 7.AB.239.166; 7.AB.239.169; 7.AB.239.172; 7.AB.239.175; 7.AB.239.240; 7.AB.239.244; 7.AB.154.228; 7AB.154.229; 7.AB.154.230; 7.AB.154.231; 7.AB.154.236; 7.AB.154.237; 7.AB.154.238; 7.AB.154.239; 7.AB.154.154; 7.AB.154.157; 7.AB.154.166; 7.AB.154.169; 7.AB.154.172; 7.AB.154.175; 7.AB.154.240; 7.AB.154.244; 7.AB.157.228; 7.AB.157.229; 7.AB.157.230; 7.AB.157.231; 7.AB.157.236; 7.AB.157.237; 7.AB.157.238; 7.AB.157.239; 7.AB.157.154; 7.AB.157.157; 7.AB.157.166; 7.AB.157.169; 7.AB.157.172; 7.AB.157.175; 7.AB.157.240; 7.AB.157.244; 7.AB.166.228; 7.AB.166.229; 7.AB.166.230; 7.AB.166.231; 7.AB.166.236; 7.AB.166.237; 7.AB.166.238; 7.AB.166.239; 7.AB.166.154; 7.AB.166.157; 7.AB.166.166; 7.AB.166.169; 7.AB.166.172; 7.AB.166.175; 7.AB.166.240; 7.AB.166.244; 7.AB.169.228; 7.AB.169.229; 7.AB.169.230; 7.AB.169.231; 7.AB.169.236; 7.AB.169.237; 7.AB.169.238; 7.AB.169.239; 7.AB.169.154; 7.AB.169.157; 7.AB.169.166; 7.AB.169.169; 7.AB.169.172; 7.AB.169.175; 7.AB.169.240; 7.AB.169.244; 7.AB.172.228; 7.AB.172.229; 7.AB.172.230; 7.AB.172.231; 7.AB.172.236; 7.AB.172.237; 7.AB.172.238; 7.AB.172.239; 7.AB.172.154; 7.AB.172.157; 7.AB.172.166; 7.AB.172.169; 7.AB.172.172; 7.AB.172.175; 7.AB.172.240; 7.AB.172.244; 7.AB.175.228; 7.AB.175.229; 7.AB.175.230; 7.AB.175.231; 7.AB.175.236; 7.AB.175.237; 7.AB.175.238; 7.AB.175.239; 7.AB.175.154; 7.AB.175.157; 7.AB.175.166; 7.AB.175.169; 7.AB.175.172; 7.AB.175.175; 7.AB.175.240; 7.AB.175.244; 7.AB.240.228; 7.AB.240.229; 7.AB.240.230; 7.AB.240.231; 7.AB.240.236; 7.AB.240.237; 7.AB.240.238; 7.AB.240.239; 7.AB.240-154; 7.AB.240.157; 7.AB.240.166; 7.AB.240.169; 7.AB.240.172; 7AB.24Q.175; 7.AB.240.240; 7.AB.240.244; 7.AB.244.228; 7.AB.244.229; 7.AB.244.230; 7.AB.244.231; 7.AB.244.236; 7.AB.244.237; 7.AB.244.238; 7AB.244.239; 7.AB.244.154; 7.AB.244.157; 7.AB.244.166; 7.AB.244.169; 7.AB.244.172; 7.AB.244.175; 7.AB.244.240; 7.AB.244.244;

Prodrugs of 7.BI

7.BI.228.228; 7.BI.228.229; 7.BI.228.230; 7.BI.228.231; 7.BI.228.236; 7.BI.228.237; 7.BI.228.238; 7.BI.228.239; 7.BL228.154; 7.BI.228.157; 7.BI.228.166; 7.BI.228.169; 7.BI.228.172; 7.BI.228.175; 7.BI.228.240; 7.BI.228.244; 7.BL229.228; 7.BL229.229; 7.BI.229.230; 7.BI.229.231; 7.BI.229.236; 7.BI.229.237; 7.BI.229.238; 7.BI.229.239; 7.BI.229.154; 7.BI.229.157; 7.BI.229.166; 7.BI.229.169; 7.BI.229.172; 7.BI.229.175; 7.BI.229.240; 7.BL229.244; 7.BI.230.228; 7.BI.230.229; 7.BL230.230; 7.BI.230.231; 7.BI.230.236; 7.BI.230.237; 7.BI.230.238; 7.BI.230.239; 7.BI.230.154; 7.BI.230.157; 7.BI.230.166; 7.BI.230.169; 7.BI.230.172; 7.BL230.175; 7.BI.230.240; 7.BI.230.244; 7.BI.231.228; 7.BI.231.229; 7.BI.231.230; 7.BI.231.231; 7.BI.231.236; 7.BI.231.237; 7.BI.231.238; 7.BI.231.239; 7.BI.231.154; 7.BI.231.157; 7.BI.231.166; 7.BI.231.169; 7.BI.231.172; 7.BI.231.175; 7.BI.231.240; 7.BI.231.244; 7.BL236.228; 7.BI.236.229; 7.BI.236.230; 7.BI.236.231; 7.BI.236.236; 7.BI.236.237; 7.BI.236.238; 7.BI.236.239; 7.BI.236.154; 7.BI.236.157; 7.BI.236.166; 7.BI.236.169; 7.BI.236.172; 7.BI.236.175; 7.BI.236.240; 7.BI.236.244; 7.BI.237.228; 7.BI.237.229; 7.BI.237.230; 7.BI.237.231; 7.BI.237.236; 7.BI.237.237; 7.BL237.238; 7.BI.237.239; 7.BI.237.154; 7.BI.237.157; 7.BL237.166; 7.BI.237.169; 7.BL237.172; 7.BI.237.175; 7.BI.237.240; 7.BI.237.244; 7.BI.238.228; 7.BI.238.229; 7.BI.238.230; 7.BI.238.231; 7.BI.238.236; 7.BI.238.237; 7.BI.238.238; 7.BI.238.239; 7.BI.238.154; 7.BI.238.157; 7.BI.238.166; 7.BI.238.169; 7.BI.238.172; 7.BI.238.175; 7.BI.238.240; 7.BI.238.244; 7.BI.239.228; 7.BI.239.229; 7.BI.239.230; 7.BI.239.231; 7.BI.239.236; 7.BI.239.237; 7.BI.239.238; 7.BI.239.239; 7.BI.239.154; 7.BI.239.157; 7.BI.239.166; 7.BL239.169; 7.BI.239.172; 7.BI.239.175; 7.BI.239.240; 7.BI.239.244; 7.BI.154.228; 7.BL154.229; 7.BI.154.230; 7.BI.154.231; 7.BI.154.236; 7.BI.154.237; 7.BI.154.238; 7.BI.154.239; 7.BI.154.154; 7.BI.154.157; 7.BI.154.166; 7.BI.154.169; 7.BI.154.172; 7.BI.154.175; 7.BI.154.240; 7.BI.154.244; 7.BI.157.228; 7.BI.157.229; 7.BI.157.230; 7.BI.157.231; 7.BI.157.236; 7.BI.157.237; 7.BI.157.238; 7.BI.157.239; 7.BI.157.154; 7.BI.157.157; 7.BI.157.166; 7.BI.157.169; 7.BI.157.172; 7.BI.157.175; 7.BI.157.240; 7.BL157.244; 7.BI.166.228; 7.BI.166.229; 7.BI.166.230; 7.BI.166.231; 7.BI.166.236; 7.BI.166.237; 7.BI.166.238; 7.BI.166.239; 7.BI.166.154; 7.BI.166.157; 7.BI.166.166; 7.BI.166.169; 7.BI.166.172; 7.BI.166.175; 7.BI.166.240; 7.BI.166.244; 7.BI.169.228; 7.BI.169.229; 7.BI.169.230; 7.BI.169.231; 7.BI.169.236; 7.BI.169.237; 7.BI.169.238; 7.BI.169.239; 7.BI.169.154; 7.BI.169.157; 7.BI.169.166; 7.BI.169.169; 7.BL169.172; 7.BI.169.175; 7.BI.169.240; 7.BI.169.244; 7.BI.172.228; 7.BI.172.229; 7.BI.172.230; 7.BL172.231; 7.BI.172.236; 7.BI.172.237; 7.BI.172.238; 7.BI.172.239; 7.BI.172.154; 7.BI.172.157; 7.BI.172.166; 7.BI.172.169; 7.BI.172.172; 7.BI.172.175; 7.BI172.240; 7.BI.172.244; 7.BI.175.228; 7.BI.175.229; 7.BI.175.230; 7.BI.175.231; 7.BI.175.236; 7.BI.175.237; 7.BI.175.238; 7.BI.175.239; 7.BI.175.154; 7.BI.175.157; 7.BI.175.166; 7.BL175.169; 7.BI.175.172; 7.BI.175.175; 7.BI.175.240; 7.BI.175.244; 7.BI.240.228; 7.BI.240.229; 7.BI.240.230; 7.BI.240.231; 7.BI.240.236; 7.BI.24Q.237; 7.BI.240.238; 7.BL240.239; 7.BI.240.154; 7.BI.240.157; 7.BI.240.166; 7.BI.240.169; 7.BI.240.172; 7.BI.240.175; 7.BI.240.240; 7.BI.240.244; 7.BI.244.228; 7.BI.244.229; 7.BI.244.230; 7.BI.244.231; 7.BI.244.236; 7.BI.244.237; 7.BI.244.238; 7.BI.244.239; 7.BI.244.154; 7.BI.244.157; 7.BI.244.166; 7.BI.244.169; 7.BI.244.172; 7.BI.244.175; 7.BI.244.240; 7.BL244.244;

Prodrugs of 7.1

7.1.228.228; 7.1.228.229; 7.1.228.230; 7.1.228.231; 7.1.228.236; 7.1.228.237; 7.1.228.238; 7.1.228.239; 7.1.228.154; 7.1.228.157; 7.1.228.166; 7.1.228.169; 7.1.228.172; 7.1.228.175; 7.1.228.240; 7.1.228.244; 7.1.229.228; 7.1.229.229; 7.1.229.230; 7.1.229.231; 7.1.229.236; 7.1.229.237; 7.1.229.238; 7.1.229.239; 7.1.229.154; 7.1.229.157; 7.1.229.166; 7.1.229.169; 7.1.229.172; 7.1.229.175; 7.1.229.240; 7.1.229.244; 7.1.230.228; 7.1.230.229; 7.1.230.230; 7.1.230.231; 7.1.230.236; 7.1.230.237; 7.1.230.238; 7.1.230.239; 7.1.230.154; 7.1.230.157; 7.1.230.166; 7.1.230.169; 7.1.230.172; 7.1.230.175; 7.1.230.240; 7.1.230.244; 7.1.231.228; 7.1.231.229; 7.1.231.230; 7.1.231.231; 7.1.231.236; 7.1.231.237; 7.1.231.238; 7.1.231.239; 7.1.231.154; 7.1.231.157; 7.1.231.166; 7.1.231.169; 7.1.231.172; 7.1.231.175; 7.1.231.240; 7.1.231.244; 7.1.236.228; 7.1.236.229; 7.1.236.230; 7.1.236.231; 7.1.236.236; 7.1.236.237; 7.1.236.238; 7.1.236.239; 7.1.236.154; 7.1.236.157; 7.1.236.166; 7.1.236.169; 7.1.236.172; 7.1.236.175; 7.1.236.240; 7.1.236.244; 7.1.237.228; 7.1.237.229; 7.1.237.230; 7.1.237.231; 7.1.237.236; 7.1.237.237; 7.1.237.238; 7.1.237.239; 7.1.237.154; 7.1.237.157; 7.1.237.166; 7.1.237.169; 7.1.237.172; 7.1.237.175; 7.1.237.240; 7.1.237.244; 7.1.238.228; 7.1.238.229; 7.1.238.230; 7.1.238.231; 7.1.238.236; 7.1.238.237; 7.1.238.238; 7.1.238.239; 7.1.238.154; 7.1.238.157; 7.1.238.166; 7.1.238.169; 7.1.238.172; 7.1.238.175; 7.1.238.240; 7.1.238.244; 7.1.239.228; 7.1.239.229; 7.1.239.230; 7.1.239.231; 7.1.239.236; 7.1.239.237; 7.1.239.238; 7.1.239.239; 7.1.239.154; 7.1.239.157; 7.1.239.166; 7.1.239.169; 7.1.239.172; 7.1.239.175; 7.1.239.240; 7.1.239.244; 7.1.154.228; 7.1.154.229; 7.1.154.230; 7.1.154.231; 7.1.154.236; 7.1.154.237; 7.1.154.238; 7.1.154.239; 7.1.154.154; 7.1.154.157; 7.1.154.166; 7.1.154.169; 7.1.154.172; 7.1.154.175; 7.1.154.240; 7.1.154.244; 7.1.157.228; 7.1.157.229; 7.1.157.230; 7.1.157.231; 7.1.157.236; 7.1.157.237; 7.1.157.238; 7.1.157.239; 7.1.157.154; 7.1.157.157; 7.1.157.166; 7.1.157.169; 7.1.157.172; 7.1.157.175; 7.1.157.240; 7.1.157.244; 7.1.166.228; 7.1.166.229; 7.1.166.230; 7.1.166.231; 7.1.166.236; 7.1.166.237; 7.1.166.238; 7.1.166.239; 7.1.166.154; 7.1.166.157; 7.1.166.166; 7.1.166.169; 7.1.166.172; 7.1.166.175; 7.1.166.240; 7.1.166.244; 7.1.169.228; 7.1.169.229; 7.1.169.230; 7.1.169.231; 7.1.169.236; 7.1.169.237; 7.1.169.238; 7.1.169.239; 7.1.169.154; 7.1.169.157; 7.1.169.166; 7.1.169.169; 7.1.169.172; 7.1.169.175; 7.1.169.240; 7.1.169.244; 7.1.172.228; 7.1.172.229; 7.1.172.230; 7.1.172.231; 7.1.172.236; 7.1.172.237; 7.1.172.238; 7.1.172.239; 7.1.172.154; 7.1.172.157; 7.1.172.166; 7.1.172.169; 7.1.172.172; 7.1.172.175; 7.1.172.240; 7.1.172.244; 7.1.175.228; 7.1.175.229; 7.1.175.230; 7.1.175.231; 7.1.175.236; 7.1.175.237; 7.1.175.238; 7.1.175.239; 7.1.175.154; 7.1.175.157; 7.1.175.166; 7.1.175.169; 7.1.175.172; 7.1.175.175; 7.1.175.240; 7.1.175.244; 7.1.240.228; 7.1.240.229; 7.1.240.230; 7.1.240-231; 7.1.240.236; 7.1.240.237; 7.1.240.238; 7.1.240.239; 7.1.240.154; 7.1.240.157; 7.1.240.166; 7.1.240.169; 7.1.240.172; 7.1.240.175; 7.1.240.240; 7.1.240.244; 7.1.244.228; 7.1.244.229; 7.1.244.230; 7.1.244.231; 7.1.244.236; 7.1.244.237; 7.1.244.238; 7.1.244.239; 7.1.244.154; 7.1.244.157; 7.1.244.166; 7.1.244.169; 7.1.244.172; 7.1.244.175; 7.1.244.240; 7.1.244.244;

Prodrugs of 7.T

7.J.228.228; 7.J.228.229; 7J.228.230; 7.J.228.231; 7.J.228.236; 7.J.228.237; 7.J.228.238; 7.J.228239; 7.J.228.154; 7J.228.157; 7J.228.166; 7J.228.169; 7J.228.172; 7J.228.175; 7J.228.240; 7.J.228.244; 7J.229.228; 7J.229.229; 7J.229.230; 7J.229.231; 7J.229.236; 7.J.229.237; 7J.229.238; 7J.229.239; 7J.229.154; 7J.229.157; 7J.229.166; 7.J.229.169; 7J.229.172; 7J.229.175; 7.J.229.240; 7J.229.244; 7J.230.228; 7J.230.229; 7J.230.230; 7J.230.231; 7J.230.236; 7J.230.237; 7J.230.238; 7J.230.239; 7.J.230.154; 7J.230.157; 7J.230.166; 7J.230.169; 7J.230.172; 7J.230.175; 7J.230.240; 7.J.230.244; 7J.231.228; 7J.231.229; 7.J.231.230; 7J.231.231; 7J.231.236; 7J.231.237; 7J.231.238; 7J.231.239; 7J.231.154; 7J.231.157; 7J.231.166; 7J.231.169; 7J.231.172; 7J.231.175; 7J.231.240; 7J.231.244; 7J.236.228; 7J.236.229; 7J.236.230; 7J.236.231; 7J.236.236; 7J.236.237; 7J.236.238; 7J.236.239; 7J.236.154; 7J.236.157; 7J.236.166; 7J.236.169; 7J.236.172; 7J.236.175; 7J.236.240; 7J.236.244; 7.J.237.228; 7J.237.229; 7J.237.230; 7J.237.231; 7J.237.236; 7J.237.237; 7J.237.238; 7J.237.239; 7.J.237.154; 7.J.237.157; 7.J.237.166; 7J.237.169; 7J.237.172; 7.J.237.175; 7J.237.240; 7J.237.244; 7J.238.228; 7J.238.229; 7J.238.230; 7J.238.231; 7.J.238.236; 7J.238.237; 7J.238.238; 7J.238.239; 7.J.238.154; 7J.238.157; 7J.238.166; 7J.238.169; 7J.238.172; 7J.238.175; 7J.238.240; 7.J.238.244; 7J.239.228; 7J.239.229; 7J.239.230; 7J.239.231; 7J.239.236; 7J.239.237; 7J.239.238; 7J.239.239; 7J.239.154; 7J.239.157; 7J.239.166; 7J.239.169; 7J.239.172; 7J.239.175; 7J.239.240; 7.J.239.244; 7J.154.228; 7J.154.229; 7J.154.230; 7J.154.231; 7J.154.236; 7J.154.237; 7J.154.238; 7J.154.239; 7J.154.154; 7J.154.157; 7.J.154.166; 7J.154.169; 7J.154.172; 7J.154.175; 7J.154.240; 7J.154.244; 7J.157.228; 7.J.157.229; 7J.157.230; 7.J.157.231; 7J.157.236; 7J.157.237; 7J.157.238; 7J.157.239; 7J.157.154; 7.J.157.157; 7.J.157.166; 7J.157.169; 7J.157.172; 7J.157.175; 7J.157.240; 7J.157.244; 7.J.166.228; 7J.166.229; 7J.166.230; 7J.166.231; 7J.166.236; 7J.166.237; 7J.166.238; 7.J.166.239; 7J.166.154; 7J.166.157; 7J.166.166; 7J.166.169; 7J.166.172; 7J.166.175; 7.J.166.240; 7J.166.244; 7.J.169.228; 7J.169.229; 7J.169.230; 7J.169.231; 7J.169.236; 7J.169.237; 7J.169.238; 7J.169.239; 7J.169.154; 7J.169.157; 7.J.169.166; 7J.169.169; 7J.169.172; 7J.169.175; 7J.169.240; 7J.169.244; 7J.172.228; 7J.172.229; 7J.172.230; 7J.172.231; 7J.172.236; 7J.172.237; 7J.172.238; 7J.172.239; 7J.172.154; 7J.172.157; 7J.172.166; 7J.172.169; 7J.172.172; 7J.172.175; 7J.172.240; 7.J.172.244; 7J.175.228; 7J.175.229; 7J.175.230; 7J.175.231; 7J.175.236; 7J.175.237; 7J.175.238; 7J.175.239; 7J.175.154; 7J.175.157; 7J.175.166; 7J.175.169; 7J.175.172; 7J.175.175; 7J.175.240; 7J.175.244; 7J.240.228; 7J.240.229; 7J.240.230; 7.J.24Q.231; 7.J.240.236; 7J.240.237; 7J.240.238; 7J.240.239; 7J.240.154; 7.J.24Q.157; 7J.240.166; 7J.240.169; 7J.240.172; 7J.240.175; 7J.240.240; 7J.240.244; 7.J.244.228; 7J.244.229; 7J.244.230; 7J.244.231; 7J.244.236; 7J.244.237; 7J.244.238; 7J.244.239; 7J.244.154; 7J.244.157; 7J.244.166; 7J.244.169; 7J.244.172; 7.J.244.175; 7J.244.240; 7J.244.244;

Prodrugs of 7.L

7.L.228.228; 7.L.228.229; 7.L.228.230; 7.L.228.231; 7.L.228.236; 7.L.228.237; 7.L.228.238; 7.L.228.239; 7.L.228.154; 7.L.228.157; 7.L.228.166; 7.L.228.169; 7.L.228.172; 7.L.228.175; 7.L.228.240; 7.L.228.244; 7.L.229.228; 7.L.229.229; 7.L.229.230; 7.L.229.231; 7.L.229.236; 7.L.229.237; 7.L.229.238; 7.L.229.239; 7.L.229.154; 7.L.229.157; 7.L.229.166; 7.L.229.169; 7.L.229.172; 7.L.229.175; 7.L.229.240; 7.L.229.244; 7.L.230.228; 7.L.230.229; 7.L.230.230; 7.L.230.231; 7.L.230.236; 7.L.230.237; 7.L.230.238; 7.L.230.239; 7.L.230.154; 7.L.230.157; 7.L.230.166; 7.L.230.169; 7.L.230.172; 7.L.230.175; 7.L.230.240; 7.L.230.244; 7.L.231.228; 7.L.231.229; 7.L.231.230; 7.L.231.231; 7.L.231.236; 7.L.231.237; 7.L.231.238; 7.L.231.239; 7.L.231.154; 7.L.231.157; 7.L.231.166; 7.L.231.169; 7.L.231.172; 7.L.231.175; 7.L.231.240; 7.L.231.244; 7.L.236.228; 7.L.236.229; 7.L.236.230; 7.L.236.231; 7.L.236.236; 7.L.236.237; 7.L.236.238; 7.L.236.239; 7.L.236.154; 7.L.236.157; 7.L.236.166; 7.L.236.169; 7.L.236.172; 7.L.236.175; 7.L.236.240; 7.L.236.244; 7.L.237.228; 7.L.237.229; 7.L.237.230; 7X.237.231; 7.L.237.236; 7.L.237.237; 7.L.237.238; 7.L.237.239; 7.L.237.154; 7.L.237.157; 7.L.237.166; 7.L.237.169; 7.L.237.172; 7.L.237.175; 7.L.237.240; 7.L.237.244; 7.L.238.228; 7.L.238.229; 7.L.238.230; 7.L.238.231; 7.L.238.236; 7.L.238.237; 7.L.238.238; 7.L.238.239; 7.L.238.154; 7.L.238.157; 7.L.238.166; 7.L.238.169; 7.L.238.172; 7.L.238.175; 7.L.238.240; 7.L.238.244; 7.L.239.228; 7.L.239.229; 7.L.239.230; 7.L.239.231; 7.L.239.236; 7.L.239.237; 7.L.239.238; 7.L.239.239; 7.L.239.154; 7.L.239.157; 7.L.239.166; 7.L.239.169; 7.L.239.172; 7.L.239.175; 7.L.239.240; 7.L.239.244; 7.L.154.228; 7.L.154.229; 7.L.154.230; 7.L.154.231; 7.L.154.236; 7.L.154.237; 7.L.154.238; 7.L.154.239; 7.L.154.154; 7.L.154.157; 7.L.154.166; 7.L.154.169; 7.L.154.172; 7.L.154.175; 7.L.154.240; 7.L.154.244; 7.L.157.228; 7.L.157.229; 7.L.157.230; 7.L.157.231; 7.L.157.236; 7.L.157.237; 7.L.157.238; 7.L.157.239; 7.L.157.154; 7.L.157.157; 7.L.157.166; 7.L.157.169; 7.L.157.172; 7.L.157.175; 7.L.157.240; 7.L.157.244; 7.L.166.228; 7.L.166.229; 7.L.166.230; 7.L.166.231; 7.L.166.236; 7.L.166.237; 7.L.166.238; 7.L.166.239; 7.L.166.154; 7.L.166.157; 7.L.166.166; 7.L.166.169; 7.L.166.172; 7.L.166.175; 7.L.166.240; 7.L.166.244; 7.L.169.228; 7.L.169.229; 7.L.169.230; 7.L.169.231; 7.L.169.236; 7.L.169.237; 7.L.169.238; 7.L.169.239; 7.L.169.154; 7.L.169.157; 7.L.169.166; 7.L.169.169; 7.L.169.172; 7.L.169.175; 7.L.169.240; 7.L.169.244; 7.L.172.228; 7.L.172.229; 7.L.172.230; 7.L.172.231; 7.L.172.236; 7.L.172.237; 7.L.172.238; 7.L.172.239; 7.L.172.154; 7.L.172.157; 7.L.172.166; 7.L.172.169; 7.L.172.172; 7.L.172.175; 7.L.172.240; 7.L.172.244; 7.L.175.228; 7.L.175.229; 7.L.175.230; 7.L.175.231; 7.L.175.236; 7.L.175.237; 7.L.175.238; 7.L.175.239; 7.L.175.154; 7.L.175.157; 7.L.175.166; 7.L.175.169; 7.L.175.172; 7.L.175.175; 7.L.175.240; 7.L.175.244; 7.L.240.228; 7.L.240.229; 7.L.240.230; 7.L.240.231; 7.L.240.236; 7.L.24Q.237; 7.L.24Q.238; 7.L.24Q.239; 7.L.240.154; 7.L.240.157; 7.L.240.166; 7.L.240.169; 7.L.240.172; 7.L.240.175; 7.L.24Q.240; 7.L.240.244; 7.L.244.228; 7.L.244.229; 7.L.244.230; 7.L.244.231; 7.L.244.236; 7.L.244.237; 7.L.244.238; 7.L.244.239; 7.L.244.154; 7.L.244.157; 7.L.244.166; 7.L.244.169; 7.L.244.172; 7.L.244.175; 7.L.244.240; 7.L.244.244;

Prodrugs of 7.O

7.O.228.228; 7.O.228.229; 7.O.228.230; 7.O.228.231; 7.O.228.236; 7.O.228.237; 7.O.228.238; 7.O.228.239; 7.O.228.154; 7.O.228.157; 7.O.228.166; 7.O.228.169; 7.O.228.172; 7.O.228.175; 7.O.228.240; 7.O.228.244; 7.O.229.228; 7.O.229.229; 7.O.229.230; 7.O.229.231; 7.O.229.236; 7.O.229.237; 7.O.229.238; 7.O.229.239; 7.O.229.154; 7.O.229.157; 7.O.229.166; 7.O.229.169; 7.O.229.172; 7.O.229.175; 7.O.229.240; 7.O.229.244; 7.O.230.228; 7.O.230.229; 7.O.230.230; 7.O.230.231; 7.O.230.236; 7.O.230.237; 7.O.230.238; 7.O.230.239; 7.O.230.154; 7.O.230.157; 7.O.230.166; 7.O.230.169; 7.O.23Q.172; 7.O.230.175; 7.O.230.24Q; 7.O.230.244; 7.O.231.228; 7.O.231.229; 7.O.231.230; 7.0-231.231; 7.O.231.236; 7.O.231.237; 7.O.231.238; 7.O.231.239; 7.O.231.154; 7.O.231.157; 7.O.231.166; 7.O.231.169; 7.O.231.172; 7.O.231.175; 7.O.231.24Q; 7.O.231.244; 7.O.236.228; 7.O.236.229; 7.O.236.230; 7.O.236.231; 7.O.236.236; 7.O.236.237; 7.O.236.238; 7.O.236.239; 7.O.236.154; 7.O.236.157; 7.O.236.166; 7.O.236.169; 7.O.236.172; 7.O.236.175; 7.O.236.240; 7.O.236.244; 7.O.237.228; 7.O.237.229; 7.O.237.230; 7.O.237.231; 7.O.237.236; 7.O.237.237; 7.O.237.238; 7.O.237.239; 7.O.237.154; 7.O.237.157; 7.O.237.166; 7.O.237.169; 7.O.237.172; 7.O.237.175; 7.O.237.240; 7.O.237.244; 7.O.238.228; 7.O.238.229; 7.O.238.230; 7.Q.238.231; 7.O.238.236; 7.O.238.237; 7.O.238.238; 7.O.238.239; 7.O.238.154; 7.O.238.157; 7.O.238.166; 7.O.238.169; 7.O.238.172; 7.O.238.175; 7.O.238.24Q; 7.O.238.244; 7.O.239.228; 7.O.239.229; 7.O.239.230; 7.O.239.231; 7.O.239.236; 7.O.239.237; 7.O.239.238; 7.O.239.239; 7.O.239.154; 7.O.239.157; 7.O.239.166; 7.O.239.169; 7.O.239.172; 7.O.239.175; 7.O.239.240; 7.O.239.244; 7.O.154.228; 7.O.154.229; 7.O.154.230; 7.O.154.231; 7.O.154.236; 7.O.154.237; 7.O.154.238; 7.O.154.239; 7.O.154.154; 7.O.154.157; 7.O.154.166; 7.O.154.169; 7.O.154.172; 7.O.154.175; 7.O.154.240; 7.O.154.244; 7.O.157.228; 7.O.157.229; 7.O.157.230; 7.O.157.231; 7.O.157.236; 7.O.157.237; 7.O.157.238; 7.O.157.239; 7.O.157.154; 7.O.157.157; 7.O.157.166; 7.O.157.169; 7.O.157.172; 7.O.157.175; 7.O.157.240; 7.O.157.244; 7.O.166.228; 7.O.166.229; 7.O.166.230; 7.O.166.231; 7.O.166.236; 7.O.166.237; 7.O.166.238; 7.O.166.239; 7.O.166.154; 7.O.166.157; 7.O.166.166; 7.O.166.169; 7.O.166.172; 7.O.166.175; 7.O.166.240; 7.O.166.244; 7.O.169.228; 7.O.169.229; 7.O.169.230; 7.O.169.231; 7.O.169.236; 7.O.169.237; 7.O.169.238; 7.O.169.239; 7.O.169.154; 7.O.169.157; 7.O.169.166; 7.O.169.169; 7.O.169.172; 7.O.169.175; 7.O.169.240; 7.O.169.244; 7.O.172.228; 7.O.172.229; 7.O.172.230; 7.O.172.231; 7.O.172.236; 7.O.172.237; 7.O.172.238; 7.O.172.239; 7.O.172.154; 7.O.172.157; 7.O.172.166; 7.O.172.169; 7.O.172.172; 7.O.172.175; 7.O.172.240; 7.O.172.244; 7.O.175.228; 7.O.175.229; 7.O.175.230; 7.0.175.231; 7.O.175.236; 7.O.175.237; 7.O.175.238; 7.O.175.239; 7.O.175.154; 7.O.175.157; 7.O.175.166; 7.O.175.169; 7.O.175.172; 7.O.175.175; 7.O.175.240; 7.O.175.244; 7.O.240.228; 7.O.240.229; 7.O.240.230; 7.O.240.231; 7.O.240.236; 7.O.240.237; 7.O.240.238; 7.O.240.239; 7.O.240.154; 7.O.240.157; 7.O.240.166; 7.O.240.169; 7.O.240.172; 7.O.240.175; 7.O.240.240; 7.O.240.244; 7.O.244.228; 7.O.244.229; 7.O.244.230; 7.O.244.231; 7.O.244.236; 7.O.244.237; 7.O.244.238; 7.O.244.239; 7.O.244.154; 7.O.244.157; 7.O.244.166; 7.O.244.169; 7.O.244.172; 7.O.244.175; 7.O.244.240; 7.O.244.244;

Prodrugs of 7.P

7.P.228.228; 7.P.228.229; 7.P.228.230; 7.P.228.231; 7.P.228.236; 7.P.228.237; 7.P.228.238; 7.P.228.239; 7.P.228.154; 7.P.228.157; 7.P.228.166; 7.P.228.169; 7.P.228.172; 7.P.228.175; 7.P.228.240; 7.P.228.244; 7.P.229.228; 7.P.229.229; 7.P.229.230; 7.P.229.231; 7.P.229.236; 7.P.229.237; 7.P.229.238; 7.P.229.239; 7.P.229.154; 7.P.229.157; 7.P.229.166; 7.P.229.169; 7.P.229.172; 7.P.229.175; 7.P.229.240; 7.P.229.244; 7.P.230.228; 7.P.230.229; 7.P.230.230; 7.P.230.231; 7.P.230.236; 7.P.230.237; 7.P.230.238; 7.P.230.239; 7.P.230.154; 7.P.230.157; 7.P.230.166; 7.P.230.169; 7.P.230.172; 7.P.230.175; 7.P.230.24Q; 7.P.230.244; 7.P.231.228; 7.P.231.229; 7.P.231.230; 7.P.231.231; 7.P.231.236; 7.P.231.237; 7.P.231.238; 7.P.231.239; 7.P.231.154; 7.P.231.157; 7.P.231.166; 7.P.231.169; 7.P.231.172; 7.P.231.175; 7.P.231.240; 7.P.231.244; 7.P.236.228; 7.P.236.229; 7.P.236.230; 7.P.236.231; 7.P.236.236; 7.P.236.237; 7.P.236.238; 7.P.236.239; 7.P.236.154; 7.P.236.157; 7.P.236.166; 7.P.236.169; 7.P.236.172; 7.P.236.175; 7.P.236.240; 7.P.236.244; 7.P.237.228; 7.P.237.229; 7.P.237.230; 7.P.237.231; 7.P.237.236; 7.P.237.237; 7.P.237.238; 7.P.237.239; 7.P.237.154; 7.P.237.157; 7.P.237.166; 7.P.237.169; 7.P.237.172; 7.P.237.175; 7.P.237.24Q; 7.P.237.244; 7.P.238.228; 7.P.238.229; 7.P.238.230; 7.P.238.231; 7.P.238.236; 7.P.238.237; 7.P.238.238; 7.P.238.239; 7.P.238.154; 7.P.238.157; 7.P.238.166; 7.P.238.169; 7.P.238.172; 7.P.238.175; 7.P.238.240; 7.P.238.244; 7.P.239.228; 7.P.239.229; 7.P.239.230; 7.P.239.231; 7.P.239.236; 7.P.239.237; 7.P.239.238; 7.P.239.239; 7.P.239.154; 7.P.239.157; 7.P.239.166; 7.P.239.169; 7.P.239.172; 7.P.239.175; 7.P.239.240; 7.P.239.244; 7.P.154.228; 7.P.154.229; 7.P.154.230; 7.P.154.231; 7.P.154.236; 7.P.154.237; 7.P.154.238; 7.P.154.239; 7.P.154.154; 7.P.154.157; 7.P.154.166; 7.P.154.169; 7.P.154.172; 7.P.154.175; 7.P.154.240; 7.P.154.244; 7.P.157.228; 7.P.157.229; 7.P.157.230; 7.P.157.231; 7.P.157.236; 7.P.157.237; 7.P.157.238; 7.P.157.239; 7.P.157.154; 7.P.157.157; 7.P.157.166; 7.P.157.169; 7.P.157.172; 7.P.157.175; 7.P.157.240; 7.P.157.244; 7.P.166.228; 7.P.166.229; 7.P.166.230; 7.P.166.231; 7.P.166.236; 7.P.166.237; 7.P.166.238; 7.P.166.239; 7.P.166.154; 7.P.166.157; 7.P.166.166; 7.P.166.169; 7.P.166.172; 7.P.166.175; 7.P.166.240; 7.P.166.244; 7.P.169.228; 7.P.169.229; 7.P.169.230; 7.P.169.231; 7.P.169.236; 7.P.169.237; 7.P.169.238; 7.P.169.239; 7.P.169.154; 7.P.169.157; 7.P.169.166; 7.P.169.169; 7.P.169.172; 7.P.169.175; 7.P.169.240; 7.P.169.244; 7.P.172.228; 7.P.172.229; 7.P.172.230; 7.P.172.231; 7.P.172.236; 7.P.172.237; 7.P.172.238; 7.P.172.239; 7.P.172.154; 7.P.172.157; 7.P.172.166; 7.P.172.169; 7.P.172.172; 7.P.172.175; 7.P.172.240; 7.P.172.244; 7.P.175.228; 7.P.175.229; 7.P.175.230; 7.P.175.231; 7.P.175.236; 7.P.175.237; 7.P.175.238; 7.P.175.239; 7.P.175.154; 7.P.175.157; 7.P.175.166; 7.P.175.169; 7.P.175.172; 7.P.175.175; 7.P.175.240; 7.P.175.244; 7.P.240.228; 7.P.240.229; 7.P.240.230; 7.P.240.231; 7.P.240.236; 7.P.240.237; 7.P.240.238; 7.P.240.239; 7.P.240.154; 7.P.240.157; 7.P.240.166; 7.P.240.169; 7.P.240.172; 7.P.240.175; 7.P.240-240; 7.P.240.244; 7.P.244.228; 7.P.244.229; 7.P.244.230; 7.P.244.231; 7.P.244.236; 7.P.244.237; 7.P.244.238; 7.P.244.239; 7.P.244.154; 7.P.244.157; 7.P.244.166; 7.P.244.169; 7.P.244.172; 7.P.244.175; 7.P.244.240; 7.P.244.244;

Prodrugs of 7.U

7.U.228.228; 7.U.228.229; 7.U.228.230; 7.U.228.231; 7.U.228.236; 7.U.228.237; 7.U.228.238; 7.U.228.239; 7.U.228.154; 7.U.228.157; 7.U.228.166; 7.U.228.169; 7.U.228.172; 7.U.228.175; 7.U.228.240; 7.U.228.244; 7.U.229.228; 7.U.229.229; 7 ^'.U. ,229.230; 7 ^'.U .229.231; 7.U.229.236; 7.U.229.237; 7.U.229.238; 7.U.229.239; 7.U.229.154; 7.U.229.157; 7.U.229.166; 7.U.229.169; 7.U.229.172; 7.U.229.175; 7.U.229.240; 7.U.229.244; 7.U.230.228; 7.U.230.229; 7.U.230.230; 7.U.230.231; 7.U.230.236; 7.U.230.237; 7.U.230.238; 7.U.230.239; 7.U.230.154; 7.U.230.157; 7.U.230.166; 7.U.230.169; 7.U.230.172; 7.U.230.175; 7.U.230.240; 7.U.230.244; 7.U.231.228; 7.U.231.229; 7.U.231.230; 7.U.231.231; 7.U.231.236; 7.U.231.237; 7.U.231.238; 7.U.231.239; 7.U.231.154; 7.U.231.157; 7.U.231.166; 7.U.231.169; 7.U.231.172; 7.U.231.175; 7.U.231.240; 7.U.231.244; 7.U.236.228; 7.U.236.229; 7.U.236.230; 7.U.236.231; 7.U.236.236; 7.U.236.237; 7.U.236.238; 7.U.236.239; 7.U.236.154; 7.U.236.157; 7.U.236.166; 7.U.236.169; 7.U.236.172; 7.U.236.175; 7.U.236.240; 7.U.236.244; 7.U.237.228; 7.U.237.229; 7.U.237.230; 7.U.237.231; 7.U.237.236; 7.U.237.237; 7.U.237.238; 7.U.237.239; 7.U.237.154; 7.U-237.157; 7.U.237.166; 7.U.237.169; 7.U.237.172; 7.U.237.175; 7.U.237.240; 7.U.237.244; 7.U.238.228; 7.U.238.229; 7.U-238.230; 7.U.238.231; 7.U.238.236; 7.U.238.237; 7.U.238.238; 7.U.238.239; 7.U.238.154; 7.U.238.157; 7.U.238.166; 7.U.238.169; 7.U.238.172; 7.U.238.175; 7.U.238.240; 7.U.238.244; 7.U.239.228; 7.U.239.229; 7.U.239.230; 7.U.239.231; 7.U.239.236; 7.U.239.237; 7.U.239.238; 7.U.239.239; 7.U.239.154; 7.U.239.157; 7.U.239.166; 7.U.239.169; 7.U.239.172; 7.U.239.175; 7.U.239.240; 7.U.239.244; 7.U.154.228; 7.U.154.229; 7.U.154.230; 7.U.154.231; 7.U.154.236; 7.U.154.237; 7.U.154.238; 7.U.154.239; 7.U.154.154; 7.U.154.157; 7.U.154.166; 7.U.154.169; 7.U.154.172; 7.U.154.175; 7.U.154.240; 7.U.154.244; 7.U.157.228; 7.U.157.229; 7.U.157.230; 7.U.157.231; 7.U.157.236; 7.U.157.237; 7.U.157.238; 7.U.157.239; 7.U.157.154; 7.U.157.157; 7.U.157.166; 7.U.157.169; 7.U.157.172; 7.U.157.175; 7.U.157.240; 7.U.157.244; 7.U.166.228; 7.U.166.229; 7.U.166.230; 7.U.166.231; 7.U.166.236; 7.U.166.237; 7.U.166.238; 7.U.166.239; 7.U.166.154; 7.U.166.157; 7.U.166.166; 7.U.166.169; 7.U.166.172; 7.U.166.175; 7.U.166.240; 7.U.166.244; 7.U.169.228; 7.U.169.229; 7.U.169.230; 7.U.169.231; 7.U.169.236; 7.U.169.237; 7.U.169.238; 7.U.169.239; 7.U.169.154; 7.U.169.157; 7.U.169.166; 7.U.169.169; 7.U.169.172; 7.U.169.175; 7.U.169.240; 7.U.169.244; 7.U.172.228; 7.U.172.229; 7.U.172.230; 7.U.172.231; 7.U.172.236; 7.U.172.237; 7.U.172.238; 7.U.172.239; 7.U.172.154; 7.U.172.157; 7.U.172.166; 7.U.172.169; 7.U.172.172; 7.U.172.175; 7.U.172.240; 7.U.172.244; 7.U.175.228; 7.U.175.229; 7.U.175.230; 7.U.175.231; 7.U.175.236; 7.U.175.237; 7.U.175.238; 7.U.175.239; 7.U.175.154; 7.U.175.157; 7.U.175.166; 7.U.175.169; 7.U.175.172; 7.U.175.175; 7.U.175.240; 7.U.175.244; 7.U.240.228; 7.U.240.229; 7.U.240.230; 7.U.240.231; 7.U.240.236; 7.U.240.237; 7.U.24Q.238; 7.U.240.239; 7.U.240.154; 7.U.240.157; 7.U.240.166; 7.U.240.169; 7.U.240.172; 7.U.240.175; 7.U.240.240; 7.U.240.244; 7.U.244.228; 7.U.244.229; 7.U.244.230; 7.U.244.231; 7.U.244.236; 7.U.244.237; 7.U.244.238; 7.U.244.239; 7.U.244.154; 7.U.244.157; 7.U.244.166; 7.U.244.169; 7.U.244.172; 7.U.244.175; 7.U.244.240; 7.U.244.244;

Prodrugs of 7.CD

7.CD.228.228; 7.CD.228.229; 7.CD.228.230; 7.CD.228.231; 7.CD.228.236; 7.CD.228.237; 7.CD.228.238; 7.CD.228.239; 7.CD.228.154; 7.CD.228.157; 7.CD.228.166; 7.CD.228.169; 7.CD-228.172; 7.CD.228.175; 7.CD.228.240; 7.CD.228.244; 7.CD.229.228; 7.CD.229.229; 7.CD.229.230; 7.CD.229.231; 7.CD.229.236; 7.CD.229.237; 7.CD.229.238; 7.CD.229.239; 7.CD.229.154; 7.CD.229.157; 7.CD.229.166; 7.CD.229.169; 7.CD.229.172; 7.CD.229.175; 7.CD.229.240; 7.CD.229.244; 7.CD.230.228; 7.CD.230.229; 7.CD.230.230; 7.CD.230.231; 7.CD.230.236; 7.CD.230.237; 7.CD.230.238; 7.CD.230.239; 7.CD.230.154; 7.CD.230.157; 7.CD.230.166; 7.CD.230.169; 7.CD.230.172; 7.CD.230.175; 7.CD.23Q.240; 7.CD.230.244; 7.CD.231.228; 7.CD.231.229; 7.CD.231.230; 7.CD.231.231; 7.CD.231.236; 7.CD.231.237; 7.CD.231.238; 7.CD.231.239; 7.CD.231.154; 7.CD.231.157; 7.CD.231.166; 7.CD.231.169; 7.CD.231.172; 7.CD.231.175; 7.CD.231.240; 7.CD.231.244; 7.CD.236.228; 7.CD.236.229; 7.CD.236.230; 7..CD. ,236. ,231; 7.CD.236.236; 7.CD.236.237; 7.CD.236.238; 7.CD.236.239; 7.CD.236.154; 7.CD.236.157; 7.CD.236.166; 7.CD.236.169; 7.CD.236.172; 7.CD.236.175; 7.CD.236.240; 7.CD.236.244; 7.CD.237.228; 7.CD.237.229; 7.CD.237.230; 7.CD.237.231; 7.CD.237.236; 7.CD.237.237; 7.CD.237.238; 7.CD.237.239; 7.CD.237.154; 7.CD.237.157; 7.CD.237.166; 7.CD.237.169; 7.CD.237.172; 7.CD.237.175; 7.CD.237.240; 7.CD.237.244; 7.CD.238.228; 7.CD.238.229; 7.CD.238.230; 7.CD.238.231; 7.CD.238.236; 7.CD.238.237; 7.CD.238.238; 7.CD.238.239; 7.CD.238.154; 7.CD.238.157; 7.CD.238.166; 7.CD.238.169; 7.CD.238.172; 7.CD.238.175; 7.CD.238.240; 7.CD.238.244; 7.CD.239.228; 7.CD.239.229; 7.CD.239.230; 7.CD.239.231; 7.CD.239.236; 7.CD.239.237; 7.CD.239.238; 7.CD.239.239; 7.CD.239.154; 7.CD.239.157; 7.CD.239.166; 7.CD.239.169; 7.CD.239.172; 7.CD.239.175; 7.CD.239.240; 7.CD.239.244; 7.CD.154.228; 7.CD.154.229; 7.CD.154.230; 7.CD.154.231; 7.CD.154.236; 7.CD.154.237; 7.CD.154.238; 7.CD.154.239; 7.CD.154.154; 7.CD.154.157; 7.CD.154.166; 7.CD.154.169; 7.CD.154.172; 7.CD.154.175; 7.CD.154.240; 7.CD.154.244; 7.CD.157.228; 7.CD.157.229; 7.CD.157.230; 7.CD.157.231; 7.CD.157.236; 7.CD.157.237; 7.CD.157.238; 7.CD.157.239; 7.CD.157.154; 7.CD.157.157; 7.CD.157.166; 7.CD.157.169; 7.CD.157.172; 7.CD.157.175; 7.CD.157.240; 7.CD.157.244; 7.CD.166.228; 7.CD.166.229; 7.CD.166.230; 7.CD.166.231; 7.CD.166.236; 7.CD.166.237; 7.CD.166.238; 7.CD.166.239; 7.CD.166.154; 7.CD.166.157; 7.CD.166.166; 7.CD.166.169; 7.CD.166.172; 7.CD.166.175; 7.CD.166.240; 7.CD.166.244; 7.CD.169.228; 7.CD.169.229; 7.CD.169.230; 7.CD.169.231; 7.CD.169.236; 7.CD.169.237; 7.CD.169.238; 7.CD.169.239; 7.CD.169.154; 7.CD.169.157; 7.CD.169.166; 7.CD.169.169; 7.CD.169.172; 7.CD.169.175; 7.CD.169.240; 7.CD.169.244; 7.CD.172.228; 7.CD.172.229; 7.CD.172.230; 7.CD.172.231; 7.CD.172.236; 7.CD.172.237; 7.CD.172.238; 7.CD.172.239; 7.CD.172.154; 7.CD.172.157; 7.CD.172.166; 7.CD.172.169; 7.CD.172.172; 7.CD.172.175; 7.CD.172.240; 7.CD.172.244; 7.CD.175.228; 7.CD.175.229; 7.CD.175.230; 7.CD.175.231; 7.CD.175.236; 7.CD.175.237; 7.CD.175.238; 7.CD.175.239; 7.CD.175.154; 7. CD.175.157; 7.CP.175.166; 7. CD.175.169; 7. CD.175.172; 7.CD.175.175; 7.CD.175.240; 7.CD.175.244; 7.CD.240.228; 7.CD.240.229; 7.CD.24Q.230; 7.CD.240.231; 7.CD.240.236; 7.CD.240.237; 7.CD.240.238; 7.CD.240.239; 7.CD.240.154; 7.CD.24Q.157; 7.CD.240.166; 7.CD.240.169; 7.CD.240.172; 7.CD.240.175; 7.CD.240.240; 7.CD.240.244; 7.CD.244.228; 7.CP.244.229; 7.CD.244.230; 7.CD.244.231; 7.CD.244.236; 7.CD.244.237; 7.CD.244.238; 7.CD.244.239; 7.CD.244.154; 7.CD.244.157; 7.CD.244.166; 7.CD.244.169; 7.CD.244.172; 7.CD.244.175; 7.CD.244.240; 7.CD.244.244;

Prodrugs of 7.EB

7.EB.228.228; 7.EB.228.229; 7.EB.228.230; 7.EB.228.231; 7.EB.228.236; 7.EB.228.237; 7.EB.228.238; 7.EB.228.239; 7.EB.228.154; 7.EB.228.157; 7.EB.228.166; 7.EB.228.169; 7.EB.228.172; 7.EB.228.175; 7.EB.228.240; 7.EB.228.244; 7.EB.229.228; 7.EB.229.229; 7.EB.229.230; 7.EB.229.231; 7.EB.229.236; 7.EB.229.237; 7.EB.229.238; 7.EB.229.239; 7.EB.229.154; 7.EB.229.157; 7.EB.229.166; 7.EB.229.169; 7.EB.229.172; 7.EB.229.175; 7.EB.229.240; 7.EB.229.244; 7.EB.230.228; 7.EB.230.229; 7.EB.230.230; 7.EB.230.231; 7.EB.230.236; 7.EB.230.237; 7.EB.230.238; 7.EB.230.239; 7.EB.230.154; 7.EB.230.157; 7.EB.23Q.166; 7.EB.230.169; 7.EB.230.172; 7.EB.230.175; 7.EB.230.240; 7.EB.230.244; 7.EB.231.228; 7.EB.231.229; 7.EB.231.230; 7.EB.231.231; 7.EB.231.236; 7.EB.231.237; 7.EB.231.238; 7.EB.231.239; 7.EB.231.154; 7.EB.231.157; 7.EB.231.166; 7.EB.231.169; 7.EB.231.172; 7.EB.231.175; 7.EB.231.240; 7.EB.231.244; 7.EB.236.228; 7.EB.236.229; 7.EB.236.230; 7.EB.236.231; 7.EB.236.236; 7.EB.236.237; 7.EB.236.238; 7.EB.236.239; 7.EB.236.154; 7.EB.236.157; 7.EB.236.166; 7.EB.236.169; 7.EB.236.172; 7.EB.236.175; 7.EB.236.240; 7.EB.236.244; 7.EB.237.228; 7.EB.237.229; 7.EB.237.230; 7.EB.237.231; 7.EB.237.236; 7.EB.237.237; 7.EB.237.238; 7.EB.237.239; 7.EB.237.154; 7.EB.237.157; 7.EB.237.166; 7.EB.237.169; 7.EB.237.172; 7.EB.237.175; 7.EB.237.240; 7.EB.237.244; 7.EB.238.228; 7.EB.238.229; 7.EB.238.230; 7.EB.238.231; 7.EB.238.236; 7.EB.238.237; 7.EB.238.238; 7.EB.23.8.239; 7.EB.238.154; 7.EB.238.157; 7.EB.238.166; 7.EB.238.169; 7.EB.238.172; 7.EB.238.175; 7.EB.238.240; 7.EB.238.244; 7.EB.239.228; 7.EB.239.229; 7.EB.239.230; 7.EB.239.231; 7.EB.239.236; 7.EB.239.237; 7.EB.239.238; 7.EB.239.239; 7.EB.239.154; 7.EB.239.157; 7.EB.239.166; 7.EB.239.169; 7.EB.239.172; 7.EB.239.175; 7.EB.239.240; 7.EB.239.244; 7.EB.154.228; 7.EB.154.229; 7.EB.154.230; 7.EB.154.231; 7.EB.154.236; 7.EB.154.237; 7.EB.154.238; 7.EB.154.239; 7.EB.154.154; 7.EB.154.157; 7.EB.154.166; 7.EB.154.169; 7.EB.154.172; 7.EB.154.175; 7.EB.154.240; 7.EB.154.244; 7.EB.157.228; 7.EB.157.229; 7.EB.157.230; 7.EB.157.231; 7.EB.157.236; 7.EB.157.237; 7.EB.157.238; 7.EB.157.239; 7.EB.157.154; 7.EB.157.157; 7.EB.157.166; 7.EB.157.169; 7.EB.157.172; 7.EB.157.175; 7.EB.157.240; 7.EB.157.244; 7.EB.166.228; 7.EB.166.229; 7.EB.166.230; 7.EB.166.231; 7.EB.166.236; 7.EB.166.237; 7.EB.166.238; 7.EB.166.239; 7.EB.166.154; 7.EB.166.157; 7.EB.166.166; 7.EB.166.169; 7.EB.166.172; 7.EB.166.175; 7.EB.166.24Q; 7.EB.166.244; 7.EB.169.228; 7.EB.169.229; 7.EB.169.230; 7.EB.169.231; 7.EB.169.236; 7.EB.169.237; 7.EB.169.238; 7.EB.169.239; 7.EB.169.154; 7.EB.169.157; 7.EB.169.166; 7.EB.169.169; 7.EB.169.172; 7.EB.169.175; 7.EB.169.240; 7.EB.169.244; 7, ,EB.172.228; 7.EB.172.229; 7.EB.172.230; 7.EB.172.231; 7.EB.172.236; 7.EB.172.237; 7.EB.172.238; 7.EB.172.239; 7.EB.172.154; 7.EB.172.157; 7.EB.172.166; 7.EB.172.169; 7.EB.172.172; 7.EB.172.175; 7.EB.172.240; 7.EB.172.244; 7.EB.175.228; 7.EB.175.229; 7.EB.175.230; 7.EB.175.231; 7.EB.175.236; 7.EB.175.237; 7.EB.175.238; 7.EB.175.239; 7.EB.175.154; 7.EB.175.157; 7.EB.175.166; 7.EB.175.169; 7.EB.175.172; 7.EB.175.175; 7.EB.175.240; 7.EB.175.244; 7.EB.24Q.228; 7.EB.24Q.229; 7.EB.240.230; 7.EB.240.231; 7.EB.24Q.236; 7.EB.240.237; 7.EB.240.238; 7.EB.240.239; 7.EB.240.154; 7.EB.240.157; 7.EB.240.166; 7.EB.240.169; 7.EB.240.172; 7.EB.240.175; 7.EB.240.240; 7.EB.24Q.244; 7.EB.244.228; 7.EB.244.229; 7.EB.244.230; 7.EB.244.231; 7.EB.244.236; 7.EB.244.237; 7.EB.244.238; 7.EB.244.239; 7.EB.244.154; 7.EB.244.157; 7.EB.244.166; 7.EB.244.169; 7.EB.244.172; 7.EB.244.175; 7.EB.244.240; 7.EB.244.244;

Prodrugs of 8.B

8.B.228.228; 8.B.228.229; 8.B.228.230; 8.B.228.231; 8.B.228.236; 8.B.228.237; 8.B.228.238; 8.B.228.239; 8.B.228.154; 8.B.228.157; 8.B.228.166; 8.B.228.169; 8.B.228.172; 8.B.228.175; 8.B.228.240; 8.B.228.244; 8.B.229.228; 8.B.229.229; 8.B.229.230; 8.B.229.231; 8.B.229.236; 8.B.229.237; 8.B.229.238; 8.B.229.239; 8.B.229.154; 8.B.229.157; 8.B.229.166; 8.B.229.169; 8.B.229.172; 8.B.229.175; 8.B.229.240; 8.B.229.244; 8.B.230.228; 8.B.230.229; 8.B.230.230; 8.B.230.231; 8.B.230.236; 8.B.230.237; 8.B.230.238; 8.B.230.239; 8.B.230.154; 8.B.230.157; 8.B.230.166; 8.B.230.169; 8.B.230.172; 8.B.230.175; 8.B.230.240; 8.B.230.244; 8.B.231.228; 8.B.231.229; 8.B.231.230; 8.B.231.231; 8.B.231.236; 8.B.231.237; 8.B.231.238; 8.B.231.239; 8.B.231.154; 8.B.231.157; 8.B.231.166; 8.B.231.169; 8.B.231.172; 8.B.231.175; 8.B.231.240; 8.B.231.244; 8.B.236.228; 8.B.236.229; 8.B.236.230; 8.B.236.231; 8.B.236.236; 8.B.236.237; 8.B.236.238; 8.B.236.239; 8.B.236.154; 8.B.236.157; 8.B.236.166; 8.B.236.169; 8.B.236.172; 8.B.236.175; 8.B.236.240; 8.B.236.244; 8.B.237.228; 8.B.237.229; 8.B.237.230; 8.B.237.231; 8.B.237.236; 8.B.237.237; 8.B.237.238; 8.B.237.239; 8.B.237.154; 8.B.237.157; 8.B.237.166; 8.B.237.169; 8.B.237.172; 8.B.237.175; 8.B.237.240; 8.B.237.244; 8.B.238.228; 8.B.238.229; 8.B.238.230; 8.B.238.231; 8.B.238.236; 8.B.238.237; 8.B.238.238; 8.B.238.239; 8.B.238.154; 8.B.238.157; 8.B.238.166; 8.B.238.169; 8.B.238.172; 8.B.238.175; 8.B.238.240; 8.B.238.244; 8.B.239.228; 8.B.239.229; 8.B.239.230; 8.B.239.231; 8.B.239.236; 8.B.239.237; 8.B.239.238; 8.B.239.239; 8.B.239.154; 8.B.239.157; 8.B.239.166; 8.B.239.169; 8.B.239.172; 8.B.239.175; 8.B.239.240; 8.B.239.244; 8.B.154.228; 8.B.154.229; 8.B.154.230; 8.B.154.231; 8.B.154.236; 8.B.154.237; 8.B.154.238; 8.B.154.239; 8.B.154.154; 8.B.154.157; 8.B.154.166; 8.B.154.169; 8.B.154.172; 8.B.154.175; 8.B.154.240; 8.B.154.244; 8.B.157.228; 8.B.157.229; 8.B.157.230; 8.B.157.231; 8.B.157.236; 8.B.157.237; 8.B.157.238; 8.B.157.239; 8.B.157.154; 8.B.157.157; 83.157.166; 8.B.157.169; 8.B.157.172; 8.B.157.175; 8.B.157.240; 8.B.157.244; 8.B.166.228; 8.B.166.229; 8.B.166.230; 8.B.166.231; 8.B.166.236; 8.B.166.237; 8.B.166.238; 8.B.166.239; 8.B.166.154; 8.B.166.157; 8.B.166.166; 8.B.166.169; 8.B.166.172; 8.B.166.175; 8.B.166.240; 8.B.166.244; 8.B.169.228; 8.B.169.229; 8.B.169.230; 8.B.169.231; 8.B.169.236; 8.B.169.237; 8.B.169.238; 8.B.169.239; 8.B.169.154; 8.B.169.157; 8.B.169.166; 8.B.169.169; 8.B.169.172; 8.B.169.175; 8.B.169.240; 8.B.169.244; 8.B.172.228; 8.B.172.229; 8.B.172.230; 8.B.172.231; 8.B.172.236; 8.B.172.237; 8.B.172.238; 8.B.172.239; 8.B.172.154; 8.B.172.157; 8.B.172.166; 8.B.172.169; 8.B.172.172; 8.B.172.175; 8.B.172.240; 8.B.172.244; 8.B.175.228; 8.B.175.229; 8.B.175.230; 8.B.175.231; 8.B.175.236; 8.B.175.237; 8.B.175.238; 8.B.175.239; 8.B.175.154; 8.B.175.157; 8.B.175.166; 83-175.169; 8.B.175.172; 8.B.175.175; 8.B.175.240; 8.B.175.244; 8.B.240.228; 8.B.24Q.229; 8.B.240.230; 8.B.240.231; 8.B.240.236; 8.B.240.237; 8.B.24Q.238; 8.B.240.239; 8.B.240.154; 8.B.240.157; 8.B.240.166; 8.B.240.169; 8.B.24Q.172; 8.B.240.175; 8.B.240.240; 8.B.240.244; 8.B.244.228; 8.B.244.229; 8.B.244.230; 8.B.244.231; 8.B.244.236; 8.B.244.237; 8.B.244.238; 8.B.244.239; 8.B.244.154; 8.B.244.157; 8.B.244.166; 8.B.244.169; 8.B.244.172; 8.B.244.175; 8.B.244.24Q; 8.B.244.244;

Prodrugs of 8.D

8.D.228.228; 8.D.228.229; 8.D.228.230; 8.D.228.231; 8.D.228.236; 8.D.228.237; 8.D.228.238; 8.D.228.239; 8.D.228.154; 8.D.228.157; 8.D.228.166; 8.D.228.169; 8.D.228.172; 8.D.228.175; 8.D.228.24Q; 8.D.228.244; 8.D.229.228; 8.D.229.229; 8.D.229.230; 8.D.229.231; 8.D.229.236; 8.D.229.237; 8.D.229.238; 8.D.229.239; 8.D.229.154; 8.D.229.157; 8.D.229.166; 8.D.229.169; 8.D.229.172; 8.D.229.175; 8.D.229.240; 8.D.229.244; 8.D.230.228; 8.D.230.229; 8.D.230.230; 8.D.230.231; 8.D.230.236; 8.D.230.237; 8.D.23Q.238; 8.D.230.239; 8.D.230.154; 8.D.230.157; 8.D.230.166; 8.D.230.169; 8.D.230.172; 8.D.230.175; 8.D.230.240; 8.D.230.244; 8.D.231.228; 8.D.231.229; 8.D.231.230; 8.D.231.231; 8.D.231.236; 8.D.231.237; 8.D.231.238; 8.D.231.239; 8.D.231.154; 8.D.231.157; 8.D.231.166; 8.D.231.169; 8.D.231.172; 8.D.231.175; 8.D.231.240; 8.D.231.244; 8.D.236.228; 8.D.236.229; 8.D.236.230; 8.D.236.231; 8.D.236.236; 8.D.236.237; 8.D.236.238; 8.D.236.239; 8.D.236.154; 8.D.236.157; 8.D.236.166; 8.D.236.169; 8.D.236.172; 8.D.236.175; 8.D.236.240; 8.D.236.244; 8.D.237.228; 8.D.237.229; 8.D.237.230; 8.D.237.231; 8.D.237.236; 8.D.237.237; 8.D.237.238; 8.D.237.239; 8.D.237.154; 8.D.237.157; 8.D.237.166; 8.D.237.169; 8.D.237.172; 8.D.237.175; 8.D.237.240; 8.D.237.244; 8.D.238.228; 8.D.238.229; 8.D.238.230; 8.D.238.231; 8.D.238.236; 8.D.238.237; 8.D.238.238; 8.D.238.239; 8.D.238.154; 8.D.238.157; 8.D.238.166; 8.D.238.169; 8.D.238.172; 8.D.238.175; 8.D.238.240; 8.D.238.244; 8.D.239.228; 8.D.239.229; 8.D.239.230; 8.D.239.231; 8.D.239.236; 8.D.239.237; 8.D.239.238; 8.D.239.239; 8.D.239.154; 8.D.239.157; 8.D.239.166; 8.D.239.169; 8.D.239.172; 8.D.239.175; 8.D.239.240; 8.D.239.244; 8.D.154.228; 8.D.154.229; 8.D.154.230; 8.D.154.231; 8.D.154.236; 8.D.154.237; 8.D.154.238; 8.D.154.239; 8.D.154.154; 8.D.154.157; 8.D.154.166; 8.D.154.169; 8.D.154.172; 8.D.154.175; 8.D.154.240; 8.D.154.244; 8.D.157.228; 8.D.157.229; 8.D.157.230; 8.D.157.231; 8.D.157.236; 8.D.157.237; 8.D.157.238; 8.D.157.239; 8.D.157.154; 8.D.157.157; 8.D.157.166; 8.D.157.169; 8.D.157.172; 8.D.157.175; 8.D.157.240; 8.D.157.244; 8.D.166.228; 8.D.166.229; 8.D.166.230; 8.D.166.231; 8.D.166.236; 8.D.166.237; 8.D.166.238; 8.D.166.239; 8.D.166.154; 8.D.166.157; 8.D.166.166; 8.D.166.169; 8.D.166.172; 8.D.166.175; 8.D.166.240; 8.D.166.244; 8.D.169.228; 8.D.169.229; 8.D.169.230; 8.D.169.231; 8.D.169.236; 8.D.169.237; 8.D.169.238; 8.D.169.239; 8.D.169.154; 8.D.169.157; 8.D.169.166; 8.D.169.169; 8.D.169.172; 8.D.169.175; 8.D.169.240; 8.D.169.244; 8.D.172.228; 8.D.172.229; 8.D.172.230; 8.D.172.231; 8.D.172.236; 8.D.172.237; 8.D.172.238; 8.D.172.239; 8.D.172.154; 8.D.172.157; 8.D.172.166; 8.D.172.169; 8.D.172.172; 8.D.172.175; 8.D.172.240; 8.D.172.244; 8.D.175.228; 8.D.175.229; 8.D.175.230; 8.D.175.231; 8.D.175.236; 8.D.175.237; 8.D.175.238; 8.D.175.239; 8.D.175.154; 8.D.175.157; 8.D.175.166; 8.D.175.169; 8.D.175.172; 8.D.175.175; 8.D.175.240; 8.D.175.244; 8.D.240.228; 8.D.240.229; 8.D.240.230; 8.D.24Q.231; 8.D.240.236; 8.D.240.237; 8.D.24Q.238; 8.D.24Q.239; 8.D.240.154; 8.D.240.157; 8X>.240.166; 8.D.240.169; 8.D.240.172; 8.D.24Q.175; 8.D.240.240; 8.D.240.244; 8.D.244.228; 8.D.244.229; 8.D.244.230; 8.D.244.231; 8.D.244.236; 8.D.244.237; 8.D.244.238; 8.D.244.239; 8.D.244.154; 8.D.244.157; 8.D.244.166; 8.D.244.169; 8.D.244.172; 8.D.244.175; 8.D.244.240; 8.D.244.244;

Prodrugs of 8.AB

8.AB.228.228; 8.AB.228.229; 8.AB.228.230; 8.AB.228.231; 8.AB.228.236; 8.AB.228.237; 8.AB.228.238; 8.AB.228.239; 8.AB.228.154; 8.AB.228.157; 8.AB.228.166; 8.AB.228.169; 8.AB.228.172; 8.AB.228.175; 8.AB.228.240; 8.AB.228.244; 8.AB.229.228; 8.AB.229.229; 8.AB.229.230; 8.AB.229.231; 8.AB.229.236; 8.AB.229.237; 8.AB.229.238; 8.AB.229.239; 8.AB.229.154; 8.AB.229.157; 8.AB.229.166; 8.AB.229.169; 8.AB.229.172; 8.AB.229.175; 8.AB.229.240; 8.AB.229.244; 8.AB.230.228; 8.AB.230.229; 8.AB.230.230; 8.AB.230.231; 8.AB.230.236; 8.AB.230.237; 8.AB.230.238; 8.AB.230.239; 8.AB.230.154; 8.AB.230.157; 8.AB.230.166; 8.AB.230.169; 8.AB.230.172; 8.AB.230.175; 8.AB.230.240; 8.AB.230.244; 8.AB.231.228; 8.AB.231.229; 8.AB.231.230; 8.AB.231.231; 8.AB.231.236; 8.AB.231.237; 8.AB.231.238; 8.AB.231.239; 8.AB.231.154; 8.AB.231.157; 8.AB.231.166; 8.AB.231.169; 8.AB.231.172; 8.AB.231.175; 8.AB.231.240; 8.AB-231.244; 8.AB.236.228; 8.AB.236.229; 8.AB.236.230; 8.AB.236.231; 8.AB.236.236; 8.AB.236.237; 8.AB.236.238; 8.AB.236.239; 8.AB.236.154; 8.AB.236.157; 8.AB.236.166; 8.AB.236.169; 8.AB.236.172; 8.AB.236.175; 8.AB.236.240; 8.AB.236.244; 8.AB.237.228; 8.AB.237.229; 8.AB.237.230; 8.AB.237.231; 8.AB.237.236; 8.AB.237.237; 8.AB.237.238; 8.AB.237.239; 8.AB.237.154; 8.AB.237.157; 8.AB.237.166; 8.AB.237.169; 8.AB.237.172; 8.AB.237.175; 8.AB.237.240; 8.AB.237.244; 8.AB.238.228; 8.AB.238.229; 8.AB.238.230; 8.AB.238.231; 8.AB.238.236; 8.AB.238.237; 8.AB.238.238; 8.AB.238.239; 8.AB.238.154; 8.AB.238.157; 8.AB.238.166; 8.AB.238.169; 8.AB.238.172; 8.AB.238.175; 8.AB.238.240; 8.AB.238.244; 8.AB.239.228; 8.AB.239.229; 8.AB.239.230; 8.AB.239.231; 8.AB.239.236; 8.AB.239.237; 8.AB.239.238; 8.AB.239.239; 8.AB.239.154; 8.AB.239.157; 8.AB.239.166; 8.AB.239.169; 8.AB.239.172; 8.AB.239.175; 8.AB.239.240; 8.AB.239.244; 8.AB.154.228; 8.AB.154.229; 8.AB.154.230; 8.AB.154.231; 8.AB.154.236; 8.AB.154.237; 8.AB.154.238; 8.AB.154.239; 8.AB.154.154; 8.AB.154.157; δ.AB.154.166; 8.AB.154.169; 8.AB.154.172; 8.AB.154.175; 8.AB.154.240; 8.AB.154.244; 8.AB.157.228; 8.AB.157.229; 8.AB.157.230; 8.AB.157.231; 8.AB.157.236; 8.AB.157.237; 8.AB.157.238; 8.AB.157.239; 8.AB.157.154; 8.AB.157.157; 8.AB.157.166; 8.AB.157.169; 8.AB.157.172; 8.AB.157.175; 8.AB.157.240; 8.AB.157.244; 8.AB.166.228; 8.AB.166.229; 8.AB.166.230; 8.AB.166.231; 8.AB.166.236; 8.AB.166.237; 8.AB.166.238; 8.AB.166.239; 8.AB.166.154; 8.AB.166.157; 8.AB.166.166; 8.AB.166.169; 8.AB.166.172; 8.AB.166.175; 8.AB.166.240; 8.AB.166.244; 8.AB.169.228; 8.AB.169.229; 8.AB.169.230; 8.AB.169.231; 8.AB.169.236; 8.AB.169.237; 8.AB.169.238; 8.AB.169.239; 8.AB.169.154; 8.AB.169.157; 8.AB.169.166; 8.AB.169.169; 8.AB.169.172; 8.AB.169.175; 8.AB.169.240; 8.AB.169.244; 8.AB.172.228; 8.AB.172.229; 8.AB.172.230; 8.AB.172.231; 8.AB.172.236; 8.AB.172.237; 8.AB.172.238; 8.AB.172.239; 8.AB.172.154; 8.AB.172.157; 8.AB.172.166; 8.AB.172.169; 8.AB.172.172; 8.AB.172.175; 8.AB.172.240; 8.AB.172.244; 8.AB.175.228; 8.AB.175.229; 8.AB.175.230; 8.AB.175.231; 8.AB.175.236; 8.AB.175.237; 8.AB.175.238; 8.AB.175.239; 8.AB.175.154; 8.AB.175.157; 8.AB.175.166; 8.AB.175.169; 8.AB.175.172; 8.AB.175.175; 8.AB.175.240; 8.AB.175.244; 8.AB.240.228; 8.AB.240.229; 8.AB.240.230; 8.AB.240.231; 8.AB.240.236; 8.AB.24Q.237; 8.AB.240.238; 8.AB.240.239; 8.AB.240.154; 8.AB.240.157; 8.AB.240.166; 8.AB.240.169; 8.AB.24Q.172; 8.AB.240.175; 8.AB.240.240; 8.AB.240.244; 8.AB.244.228; 8.AB.244.229; 8.AB.244.230; 8.AB.244.231; 8.AB.244.236; 8.AB.244.237; 8.AB.244.238; 8.AB.244.239; 8.AB.244.154; 8.AB.244.157; 8.AB.244.166; 8.AB.244.169; 8.AB.244.172; 8.AB.244.175; 8.AB.244.240; 8.AB.244.244;

Prodrugs of 8.BI

8.BI.228.228; 8.BI.228.229; 8.BI.228.23Q; 8.BI.228.231; 8.BI.228.236; 8.BI.228.237; 8.BI.228.238; 8.BI.228.239; 8.BI.228.154; 8.BI.228.157; 8.BI.228.166; 8.BI.228.169; 8.BI.228.172; 8.BI.228.175; 8.BI.228.240; 8.BI.228.244; 8.BI.229.228; 8.BI.229.229; 8.BI.229.230; 8.BI.229.231; 8.BI.229.236; 8.BI.229.237; 8.BI.229.238; 8.BI.229.239; 8.BI.229.154; 8.BI.229.157; 8.BI.229.166; 8.BI.229.169; 8.BI.229.172; 8.BI.229.175; 8.BI.229.240; 8.BI.229.244; 8.BI.230.228; 8.BI.230.229; 8.BI.23Q.230; 8.BI.230.231; 8.BI.230.236; 8.BI.230.237; 8.BI.230.238; 8.BI.230.239; 8.BI.230.154; 8.BI.230.157; 8.BI.230.166; 8.BI.230.169; 8.BI.230.172; 8.BI.230.175; 8.BI.230.240; 8.BI.230.244; 8.BI.231.228; 8.BI.231.229; 8.BI.231.230; 8.BI.231.231; 8.BL231.236; 8.BL231.237; 8.BI.231.238; 8.BL231.239; 8.BI.231.154; 8.BI.231.157; 8.BI.231.166; 8.BI.231.169; 8.BI.231.172; 8.BI.231.175; 8.BI.231.240; 8.BI.231.244; 8.BI.236.228; 8.BI.236.229; 8.BI.236.230; 8.BI.236.231; 8.BI.236.236; 8.BI.236.237; 8.BI.236.238; 8.BI.236.239; 8.BI.236.154; 8.BI.236.157; 8.BI.236.166; 8.BI.236.169; 8.BI.236.172; 8.BI.236.175; 8.BI.236.240; 8.BI.236.244; 8.BI.237.228; 8.BI.237.229; 8.BI.237.230; 8.BI.237.231; 8.BI.237.236; 8.BI.237.237; 8.BI.237.238; 8.BI.237.239; 8.BI.237.154; 8.BI.237.157; 8.BI.237.166; 8.BI.237.169; 8.BI.237.172; 8.BI.237.175; 8.BI.237.240; 8.BL237.244; 8.BI.238.228; 8.BI.238.229; 8.BI.238.230; 8.BI.238.231; 8.BI.238.236; 8.BI.238.237; 8.BI.238.238; 8.BI.238.239; 8.BI.238.154; 8.BI.238.157; 8.BI.238.166; 8.BI.238.169; 8.BI.238.172; 8.BI.238.175; 8.BI.238.240; 8.BI.238.244; 8.BI.239.228; 8.BI.239.229; 8.BI.239.230; 8.BI.239.231; 8.BL239.236; 8.BI.239.237; 8.BI.239.238; 8.BI.239.239; 8.BI.239.154; 8.BI.239.157; 8.BI.239.166; 8.BI.239.169; 8.BI.239.172; 8.BI.239.175; 8.BI.239.240; 8.BI.239.244; 8.BL154.228; 8.BI.154.229; 8.BI.154.230; 8.BI.154.231; 8.BI.154.236; 8.BI.154.237; 8.BI.154.238; 8.BI.154.239; 8.BI.154.154; 8.BI.154.157; 8.BI.154.166; 8.BI.154.169; 8.BI.154.172; 8.BI.154.175; 8.BI.154.240; 8.BI.154.244; 8.BI.157.228; 8.BI.157.229; 8.BI.157.230; 8.BI.157.231; 8.BI.157.236; 8.BI.157.237; 8.BI.157.238; 8.BI.157.239; 8.BI.157.154; 8.BI.157.157; 8.BI.157.166; 8.BI.157.169; 8.BI.157.172; 8.BI.157.175; 8.BI.157.240; 8.BI.157.244; 8.BI.166.228; 8.BI.166.229; 8.BI.166.230; 8.BI.166.231; 8.BI.166.236; 8.BI.166.237; 8.BI.166.238; 8.BI.166.239; 8.BI.166.154; 8.BI.166.157; 8.BI.166.166; 8.BI.166.169; 8.BI.166.172; 8.BI.166.175; 8.BI.166.240; 8.BI.166.244; 8.BI.169.228; 8.BI.169.229; 8.BI.169.230; 8.BI.169.231; 8.BI.169.236; 8.BI.169.237; 8.BI.169.238; 8.BI.169.239; 8.BI.169.154; 8.BI.169.157; 8.BI.169.166; 8.BI.169.169; 8.BI.169.172; 8.BI.169.175; 8.BI.169.240; 8.BI.169.244; 8.BI.172.228; 8.BI.172.229; 8.BI.172.230; 8.BI.172.231; 8.BI.172.236; 8.BI.172.237; 8.BI.172.238; 8.BI.172.239; 8.BI.172.154; 8.BI.172.157; 8.BI.172.166; 8.BI.172.169; 8.BI.172.172; 8.BI.172.175; 8.BI.172.240; 8.BI.172.244; 8.BI.175.228; 8.BI.175.229; 8.BI.175.230; 8.BI.175.231; 8.BI.175.236; 8.BI.175.237; 8.BI.175.238; 8.BI.175.239; 8.BI.175.154; 8.BI.175.157; 8.BI.175.166; 8.BI.175.169; 8.BI.175.172; 8.BI.175.175; 8.BI.175.240; 8.BI.175.244; 8.BI.240.228; 8.BI.240.229; 8.BI.240.230; 8.BI.240.231; 8.BI.240.236; 8.BI.24Q.237; 8.BI.24Q.238; 8.BI.240.239; 8.BL240.154; 8.BI.240.157; 8.BI.240.166; 8.BI.240.169; 8.BI.240.172; 8.BI.240.175; 8.BI.240.240; 8.BI.240.244; 8.BI.244.228; 8.BI.244.229; 8.BI.244.230; 8.BI.244.231; 8.BI.244.236; 8.BI.244.237; 8.BI.244.238; 8.BI.244.239; 8.BI.244.154; 8.BI.244.157; 8.BI.244.166; 8.BI.244.169; 8.BI.244.172; 8.BI.244.175; 8.BI.244.240; 8.BI.244.244;

Prodrugs of 8.1

8.1.228.228; 8.1.228.229; 8.1.228.230; 8.1.228.231; 8.1.228.236; 8.1.228.237; 8.1.228.238; 8.1.228.239; 8.1.228.154; 8.1.228.157; 8.1.228.166; 8.1.228.169; 8.1.228.172; 8.1.228.175; 8.1.228.240; 8.1.228.244; 8.1.229.228; 8.1.229.229; 8.1.229.230; 8.1229.231; 8.1.229.236; 8.1.229.237; 8.1.229.238; 8.1.229.239; 8.1.229.154; 8.1.229.157; 8.1.229.166; 8.1.229.169; 8.1.229.172; 8.1.229.175; 8.1.229.240; 8.1.229.244; 8.1.230.228; 8.1.230.229; 8.1.230.230; 8.1.230.231; 8.1.230.236; 8.1.230.237; 8.1.230.238; 8.1.230.239; 8.1.230.154; 8.1.230.157; 8.1.230.166; 8.1.230.169; 8.1.230-172; 8.1.230.175; 8.1.230.240; 8.1.230.244; 8.1.231.228; 8.1.231.229; 8.1.231.230; 8.1.231.231; 8.1.231.236; 8.1.231.237; 8.1.231.238; 8.1.231.239; 8.1.231.154; 8.1.231.157; 8.1.231.166; 8.1.231.169; 8.1.231.172; 8.1.231.175; 8.1.231.240; 8.1.231.244; 8.1.236.228; 8.1.236.229; 8.1.236.230; 8.1.236.231; 8.1.236.236; 8.1.236.237; 8.1.236.238; 8.1.236.239; 8.1.236.154; 8.1.236.157; 8.1.236.166; 8.1.236.169; 8.1.236.172; 8.1.236.175; 8.1.236.240; 8.1.236.244; 8.1.237.228; 8.1.237.229; 8.1.237.230; 8.1.237.231; 8.1.237.236; 8.1.237.237; 8.1.237.238; 8.1.237.239; 8.1.237.154; 8.1.237.157; 8.1.237.166; 8.1.237.169; 8.1.237.172; 8.1.237.175; 8.1.237.240; 8.1.237.244; 8.1.238.228; 8.1.238.229; 8.1.238.230; 8.1.238.231; 8.1.238.236; 8.1.238.237; 8.1.238.238; 8.1.238.239; 8.1.238.154; 8.1.238.157; 8.1.238.166; 8.1.238.169; 8.1.238.172; 8.1.238.175; 8.1.238.240; 8.1.238.244; 8.1.239.228; 8.1.239.229; 8.1.239.230; 8.1.239.231; 8.1.239.236; 8.1.239.237; 8.1.239.238; 8.1.239.239; 8.1.239.154; 8.1.239.157; 8.1.239.166; 8.1.239.169; 8.1.239.172; 8.1.239.175; 8.1.239.240; 8.1.239.244; 8.1.154.228; 8.1.154.229; 8.1.154.230; 8.1.154.231; 8.1.154.236; 8.1.154.237; 8.1.154.238; 8.1.154.239; 8.1.154.154; 8.1.154.157; 8.1.154.166; 8.1.154.169; 8.1.154.172; 8.1.154.175; 8.1.154.240; 8.1.154.244; 8.1.157.228; 8.1.157.229; 8.1.157.230; 8.1.157.231; 8.1.157.236; 8.1.157.237; 8.1.157.238; 8.1.157.239; 8.1.157.154; 8.1.157.157; 8.1.157.166; 8.1.157.169; 8.1.157.172; 8.1.157.175; 8.1.157.240; 8.1.157.244; 8.1.166.228; 8.1.166.229; 8.1.166.230; 8.1.166.231; 8.1.166.236; 8.1.166.237; 8.1.166.238; 8.1.166.239; 8.1.166.154; 8.1.166.157; 8.1.166.166; 8.1.166.169; 8.1.166.172; 8.1.166.175; 8.1.166.240; 8.1.166.244; 8.1.169.228; 8.1.169.229; 8.1.169.230; 8.1.169.231; 8.1.169.236; 8.1.169.237; 8.1.169.238; 8.1.169.239; 8.1.169.154; 8.1.169.157; 8.1.169.166; 8.1.169.169; 8.1.169.172; 8.1.169.175; 8.1.169.240; 8.1.169.244; 8.1.172.228; 8.1.172.229; 8.1.172.230; 8.1.172.231; 8.1.172.236; 8.1.172.237; 8.1.172.238; 8.1.172.239; 8.1.172.154; 8.1.172.157; 8.1.172.166; 8.1.172.169; 8.1.172.172; 8.1.172.175; 8.1.172.240; 8.1.172.244; 8.1.175.228; 8.1.175.229; 8.1.175.230; 8.1.175.231; 8.1.175.236; 8.1.175.237; 8.1.175.238; 8.1.175.239; 8.1.175.154; 8.1.175.157; 8.1.175.166; 8.1.175.169; 8.1.175.172; 8.1.175.175; 8.1.175.240; 8.1.175.244; 8.1.240.228; 8.1.240.229; 8.1.240.230; 8.1.240.231; 8.1.240.236; 8.1.240.237; 8.1.240.238; 8.1.240.239; 8.1.240.154; 8.1.240.157; 8.1.240.166; 8.1.240.169; 8.1.240.172; 8.1.240.175; 8.1.240.240; 8.1.240.244; 8.1.244.228; 8.1.244.229; 8.1.244.230; 8.1.244.231; 8.1.244.236; 8.1.244.237; 8.1.244.238; 8.1.244.239; 8.1.244.154; 8.1.244.157; 8.1.244.166; 8.1.244.169; 8.1.244.172; 8.1.244.175; 8.1.244.240; 8.1.244.244;

Prodrugs of 8.T

8.J.228.228; 8.J.228.229; 8.J.228.230; 8J.228.231; 8.J.228.236; 8.J.228.237; 8.J.228.238; 8.J.228.239; 8.J.228.154; 8.J.228.157; 8.J.228.166; 8.J.228.169; 8.J.228.172; 8.J.228.175; 8.J.228.240; 8.J.228.244; 8.J.229.228; 8J.229.229; 8 J.229.230; 8J.229.231; 8J.229.236; 8J.229.237; 8J.229.238; 8J.229.239; 8 J.229.154; 8 J.229.157; 8J.229.166; 8J.229.169; 8.J.229.172; 8J.229.175; 8J.229.240; 8J.229.244; 8J.230.228; 8J.230.229; 8J.230.230; 8J.230.231; 8J.230.236; 8J.230.237; 8J.230.238; 8J.230.239; 8.J.23Q.154; 8J.230.157; 8 J.230.166; 8J.230.169; 8J.230.172; 8J.230.175; 8J.230.240; 8.J.230.244; 8J.231.228; 8 J.231.229; 8J.231.230; 8 J.231.231; 8J.231.236; 8J.231.237; 8J.231.238; 8.J.231.239; 8J.231.154; 8J.231.157; 8J.231.166; 8J.231.169; 8J.231.172; 8J.231.175; 8.J.231.240; 8.J.231.244; 8J.236.228; 8J.236.229; 8J.236.230; 8 J.236.231; 8J.236.236; 8 J.236.237; 8J.236.238; 8J.236.239; 8J.236.154; 8J.236.157; 8J.236.166; 8J.236.169; 8J.236.172; 8J.236.175; 8J.236.240; 8J.236.244; 8 J.237.228; 8J.237.229; 8J.237.230; 8 J.237.231; 8J.237.236; 8J.237.237; 8J.237.238; 8J.237.239; 8 J.237.154; 8J.237.157; 8 J.237.166; 8J.237.169; 8J.237.172; 8J.237.175; 8J.237.240; 8 J.237.244; 8J.238.228; 8 J.238.229; 8J.238.230; 8J.238.231; 8 J.238.236; 8 J.238.237; 8 J.238.238; 8J.238.239; 8.J.238.154; 8.J.238.157; 8 J.238.166; 8 J.238.169; 8J.238.172; 8 J.238.175; 8 J.238.240; 8.J.238.244; 8J.239.228; 8J.239.229; 8 J.239.230; 8J.239.231; 8 J.239.236; 8J.239.237; 8J.239.238; 8J.239.239; 8J.239.154; 8J.239.157; 8J.239.166; 8 J.239.169; 8 J.239.172; 8J.239.175; 8 J.239.240; 8 J.239.244; 8J.154.228; 8J.154.229; 8 J.154.230; 8 J.154.231; 8J.154.236; 8J.154.237; 8J.154.238; 8J.154.239; 8J.154.154; 8 J.154.157; 8J.154.166; 8J.154.169; 8J.154.172; 8J.154.175; 8J.154.240; 8J.154.244; 8 J.157.228; 8J.157.229; 8J.157.230; 8 J.157.231; 8 J.157.236; 8 J.157.237; 8 J.157.238; 8 J.157.239; 8J.157.154; 8J.157.157; 8J.157.166; 8J.157.169; 8 J.157.172; 8J.157.175; 8 J.157.240; 8.J.157.244; 8.J.166.228; 8 J.166.229; 8.J.166.230; 8J.166.231; 8J.166.236; 8 J.166.237; 8.J.166.238; 8J.166.239; 8J.166.154; 8J.166.157; 8J.166.166; 8J.166.169; 8J.166.172; 8J.166.175; 8 J.166.240; 8J.166.244; 8J.169.228; 8J.169.229; 8J.169.230; 8J.169.231; 8 J.169.236; 8 J.169.237; 8J.169.238; 8J.169.239; 8 J.169.154; 8.J.169.157; 8 J.169.166; 8 J.169.169; 8 J.169.172; 8J.169.175; 8 J.169.240; 8 J.169.244; 8.J.172.228; 8 J.172.229; 8 J.172.230; 8J.172.231; 8J.172.236; 8J.172.237; 8J.172.238; 8J.172.239; 8J.172.154; 8J.172.157; 8 J.172.166; 8J.172.169; 8 J.172.172; 8 J.172.175; 8 J.172.240; 8J.172.244; 8 J.175.228; 8J.175.229; 8J.175.230; 8J.175.231; 8J.175.236; 8J.175.237; 8J.175.238; 8J.175.239; 8J.175.154; 8.J.175.157; 8.J.175.166; 8.J.175.169; 8.J.175.172; 8J.175.175; 8.J.175.240; 8J.175.244; 8J.240.228; 8.J.240.229; 8J.240.230; 8J.240.231; 8J.240.236; 8J.240.237; 8J.240.238; 8.J.240.239; 8J.240.154; 8J.240.157; 8 J.240.166; 8J.240.169; 8J.240.172; 8J.240.175; 8J.240.240; 8J.240.244; 8J.244.228; 8J.244.229; 8J.244.230; 8 J.244.231; 8J.244.236; 8.J.244.237; 8J.244.238; 8 J.244.239; 8.J.244.154; 8.J.244.157; 8J.244.166; 8J.244.169; 8J.244.172; 8J.244.175; 8J.244.240; 8 J.244.244;

Prodrugs of 8.L

8.L.228.228; 8.L.228.229; 8.L.228.230; 8.L.228.231; 8.L.228.236; 8.L.228.237; 8.L.228.238; 8.L.228.239; 8.L.228.154; 8.L.228.157; 8.L.228.166; 8.L.228.169; 8.L.228.172; 8.L.228.175; 8.L.228.240; 8.L.228.244; 8.L.229.228; 8.L.229.229; 8.L.229.230; 8.L.229.231; 8.L.229.236; 8.L.229.237; 8.L.229.238; 8.L.229.239; 8.L.229.154; 8.L.229.157; 8.L.229.166; 8.L.229.169; 8.L.229.172; 8.L.229.175; 8.L.229.240; 8.L.229.244; 8.L.230.228; 8.L.23Q.229; 8.L.230.230; 8.L.230.231; 8.L.230.236; 8.L.230.237; 8.L.230.238; 8.L.230.239; 8.L.230.154; 8.L.230.157; 8.L.230.166; 8.L.230.169; 8.L.230.172; 8.L.230.175; 8.L.230.240; 8.L.230.244; 8.L.231.228; 8.L.231.229; 8.L.231.230; 8.L.231.231; 8.L.231.236; 8.L.231.237; 8.L.231.238; 8.L.231.239; 8.L.231.154; 8.L.231.157; 8.L.231.166; 8.L.231.169; 8.L.231.172; 8.L.231.175; 8.L.231.240; 8.L.231.244; 8.L.236.228; 8.L.236.229; 8.L.236.230; 8.L.236.231; 8.L.236.236; 8.L.236.237; 8.L.236.238; 8.L.236.239; 8.L.236.154; 8.L.236.157; 8.L.236.166; 8.L.236.169; 8.L.236.172; 8.L.236.175; 8.L.236.240; 8.L.236.244; 8.L.237.228; 8.L.237.229; 8.L.237.230; 8.L.237.231; 8.L.237.236; 8.L.237.237; 8.L.237.238; 8.L.237.239; 8.L.237.154; 8.L.237.157; 8.L.237.166; 8.L.237.169; 8.L.237.172; 8.L.237.175; 8.L.237.240; 8.L.237.244; 8.L.238.228; 8.L.238.229; 8.L.238.230; 8.L.238.231; 8.L.238.236; 8.L.238.237; 8.L.238.238; 8.L.238.239; 8.L.238.154; 8.L.238.157; 8.L.238.166; 8.L.238.169; 8.L.238.172; 8.L.238.175; 8.L.238.240; 8.L.238.244; 8.L.239.228; 8.L.239.229; 8.L.239.230; 8.L.239.231; 8.L.239.236; 8.L.239.237; 8.L.239.238; 8.L.239.239; 8.L.239.154; 8.L.239.157; 8.L.239.166; 8.L.239.169; 8.L.239.172; 8.L.239.175; 8.L.239.240; 8.L.239.244; 8.L.154.228; 8.L.154.229; 8.L.154.230; 8.L.154.231; 8.L.154.236; 8.L.154.237; 8.L.154.238; 8.L.154.239; 8.L.154.154; 8.L.154.157; 8.L.154.166;,8.L.154.169; 8.L.154.172; 8.L.154.175; 8.L.154.240; 8.L.154.244; 8.L.157.228; 8.L.157.229; 8.L.157.230; 8.L.157.231; 8.L.157.236; 8.L.157.237; 8.L.157.238; 8.L.157.239; 8.L.157.154; 8.L.157.157; 8.L.157.166; 8.L.157.169; 8.L.157.172; 8.L.157.175; 8.L.157.240; 8.L.157.244; 8.L.166.228; 8.L.166.229; 8.L.166.230; 8.L.166.231; 8.L.166.236; 8.L.166.237; 8.L.166.238; 8.L.166.239; 8.L.166.154; 8.L.166.157; 8.L.166.166; 8.L.166.169; 8.L.166.172; 8.L.166.175; 8.L.166.240; 8.L.166.244; 8.L.169.228; 8.L.169.229; 8.L.169.230; 8.L.169.231; 8.L.169.236; 8.L.169.237; 8.L.169.238; 8.L.169.239; 8.L.169.154; 8.L.169.157; 8.L.169.166; 8.L.169.169; 8.L.169.172; 8.L.169.175; 8.L.169.240; 8.L.169.244; 8.L.172.228; 8.L.172.229; 8.L.172.230; 8.L.172.231; 8.L.172.236; 8.L.172.237; 8.L.172.238; 8.L.172.239; 8.L.172.154; 8.L.172.157; 8.L.172.166; 8.L.172.169; 8.L.172.172; 8.L.172.175; 8.L.172.240; 8.L.172.244; 8.L.175.228; 8.L.175.229; 8.L.175.230; 8.L.175.231; 8.L.175.236; 8.L.175.237; 8.L.175.238; 8.L.175.239; 8.L.175.154; 8.L.175.157; 8.L.175.166; 8.L.175.169; 8.L.175.172; 8.L.175.175; 8.L.175.240; 8.L.175.244; 8.L.240.228; 8.^.240.229; 8.L.240.230; 8.L.240.231; 8.L.240.236; 8.L.240.237; 8.L.240.238; 8.L.240.239; 8.L.24Q.154; 8.L.240.157; 8.L.240.166; 8.L.240.169; 8.L.240.172; 8.L.240.175; 8.L.240.240; 8.L.240.244; 8.L.244.228; 8.L.244.229; 8.L.244.230; 8.L.244.231; 8.L.244.236; 8.L.244.237; 8.L.244.238; 8.L.244.239; 8.L.244.154; 8.L.244.157; 8.L.244.166; 8.L.244.169; 8.L.244.172; 8.L.244.175; 8.L.244.240; 8.L.244.244;

Prodrugs of 8.O

8.O.228.228; 8.O.228.229; 8.O.228.230; 8.O.228.231; 8.O.228.236; 8.O.228.237; 8.O.228.238; 8.O.228.239; 8.O.228.154; 8.O.228.157; 8.O.228.166; 8.O.228.169; 8.O.228.172; 8.O.228.175; 8.O.228.240; 8.O.228.244; 8.O.229.228; 8.O.229.229; 8.O.229.230; 8.O.229.231; 8.O.229.236; 8.O.229.237; 8.O.229.238; 8.O.229.239; 8.O.229.154; 8.O.229.157; 8.O.229.166; 8.O.229.169; 8.O.229.172; 8.O.229.175; 8.O.229.240; 8.O.229.244; 8.O.230.228; 8.O.23Q.229; 8.O.230.230; 8.O.230.231; 8.O.230.236; 8.O.230.237; 8.Q.230.238; 8.O-230.239; 8.O.230.154; 8.O.230.157; 8.O.230.166; 8.O-230.169; 8.O.230.172; 8.O.23Q.175; 8.O.230.240; 8.O.230.244; 8.O.231.228; 8.O.231.229; 8.O.231.230; 8.O.231.231; 8.O.231.236; 8.O.231.237; 8.O.231.238; 8.O.231.239; 8.O.231.154; 8.O.231.157; 8.O.231.166; 8.O.231.169; 8.O.231.172; 8.O.231.175; 8.O.231.240; 8.O.231.244; 8.O.236.228; 8.O.236.229; 8.O.236.230; 8.O.236.231; 8.O.236.236; 8.O.236.237; 8.O.236.238; 8.O.236.239; 8.O.236.154; 8.O.236.157; 8.O.236.166; 8.O.236.169; 8.O.236.172; 8.O.236.175; 8.O.236.240; 8.O.236.244; 8.O.237.228; 8.O.237.229; 8.O.237.230; 8.O.237.231; 8.O.237.236; 8.O.237.237; 8.O.237.238; 8.O.237.239; 8.O.237.154; 8.O.237.157; 8.O.237.166; 8.O.237.169; 8.O.237.172; 8.O.237.175; 8.O.237.240; 8.O.237.244; 8.O.238.228; 8.O.238.229; 8.O.238.230; 8.O.238.231; 8.O.238.236; 8.O.238.237; 8.O.238.238; 8.O.238.239; 8.O.238.154; 8.O.238.157; 8.O.238.166; 8.O.238.169; 8.O.238.172; 8.O.238.175; 8.O.238.240; 8.O.238.244; 8.O.239.228; 8.O.239.229; 8.O.239.230; 8.O.239.231; 8.O.239.236; 8.O.239.237; 8.O.239.238; 8.O.239.239; 8.O.239.154; 8.O.239.157; 8.O.239.166; 8.O.239.169; 8.O.239.172; 8.O.239.175; 8.O.239.240; 8.O.239.244; 8.O.154.228; 8.O.154.229; 8.O.154.230; 8.O.154.231; 8.O.154.236; 8.O.154.237; 8.O.154.238; 8.O.154.239; 8.O.154.154; 8.O.154.157; 8.O.154.166; 8.O.154.169; 8.O.154.172; 8.O.154.175; 8.O.154.240; 8.O.154.244; 8.O.157.228; 8.O.157.229; 8.O.157.230; 8.O.157.231; 8.O.157.236; 8.O.157.237; 8.O.157.238; 8.O.157.239; 8.O.157.154; 8.O.157.157; 8.O.157.166; 8.O.157.169; 8.O.157.172; 8.O.157.175; 8.O.157.240; 8.O.157.244; 8.O.166.228; 8.O.166.229; 8.O.166.230; 8.O.166.231; 8.O.166.236; 8.O.166.237; 8.O.166.238; 8.O.166.239; 8.O.166.154; 8.O.166.157; 8.O.166.166; 8.O.166.169; 8.O.166.172; 8.O.166.175; 8.O.166.240; 8.O.166.244; 8.O.169.228; 8.O.169.229; 8.O.169.230; 8.O.169.231; 8.O.169.236; 8.O.169.237; 8.O.169.238; 8.O.169.239; 8.O.169.154; 8.O.169.157; 8.O.169.166; 8.O.169.169; 8.O.169.172; 8.O.169.175; 8.O.169.240; 8.O.169.244; 8.O.172.228; 8.O.172.229; 8.O.172.230; 8.O.172.231; 8.O.172.236; 8.O.172.237; 8.O.172.238; 8.O.172.239; 8.O.172.154; 8.O.172.157; 8.O.172.166; 8.O.172.169; 8.O.172.172; 8.O.172.175; 8.O.172.24Q; 8.O.172.244; 8.O.175.228; 8.O.175.229; 8.O.175.230; 8.O.175.231; 8.O.175.236; 8.O.175.237; 8.O.175.238; 8.O.175.239; 8.O.175.154; 8.O.175.157; 8.O.175.166; 8.O.175.169; 8.O.175.172; 8.O.175.175; 8.O.175.240; 8.O.175.244; 8.O.240.228; 8.O.240.229; 8.O.240.230; 8.O.240.231; 8.O.240.236; 8.O.240.237; 8.O.240.238; 8.O.240.239; 8.O.240.154; 8.O.240.157; 8.O.240.166; 8.O.240.169; 8.O.240.172; 8.O.240.175; 8.O.240.240; 8.O.240.244; 8.O.244.228; 8.O.244.229; 8.O.244.230; 8.O.244.231; 8.O.244.236; 8.O.244.237; 8.O.244.238; 8.O.244.239; 8.O.244.154; 8.O.244.157; 8.O.244.166; 8.O.244.169; 8.O.244.172; 8.O.244.175; 8.O.244.240; 8.O.244.244;

Prodrugs of 8.P

8.P.228.228; 8.P.228.229; 8.P.228.230; 8.P.228.231; 8.P.228.236; 8.P.228.237; 8.P.228.238; 8.P.228.239; 8.P.228.154; 8.P.228.157; 8.P.228.166; 8.P.228.169; 8.P.228.172; 8.P.228.175; 8.P.228.240; 8.P.228.244; 8.P.229.228; 8.P.229.229; 8.P.229.230; 8.P.229.231; 8.P.229.236; 8.P.229.237; 8.P.229.238; 8.P.229.239; 8.P.229.154; 8.P.229.157; 8.P.229.166; 8.P.229.169; 8.P.229.172; 8.P.229.175; 8.P.229.240; 8.P.229.244; 8.P.230.228; 8.P.230.229; 8.P.230.230; 8.P.230.231; 8.P.230.236; 8.P.23Q.237; 8.P.230.238; 8.P.230.239; 8.P.230.154; 8.P.23Q.157; 8.P.230.166; 8.P.230.169; 8.P.230.172; 8.P.230.175; 8.P.23Q.240; 8.P.230.244; 8.P.231.228; 8.P.231.229; 8.P.231.230; 8.P.231.231; 8.P.231.236; 8.P.231.237; 8.P.231.238; 8.P.231.239; 8.P.231.154; 8.P.231.157; 8.P.231.166; 8.P.231.169; 8.P.231.172; 8.P.231.175; 8.P.231.240; 8.P.231.244; 8.P.236.228; 8.P.236.229; 8.P.236.230; 8.P.236.231; 8.P.236.236; 8.P.236.237; 8.P.236.238; 8.P.236.239; 8.P.236.154; 8.P.236.157; 8.P.236.166; 8.P.236.169; 8.P.236.172; 8.P.236.175; 8.P.236.240; 8.P.236.244; 8.P.237.228; 8.P.237.229; 8.P.237.230; 8.P.237.231; 8.P.237.236; 8.P.237.237; 8.P.237.238; 8.P.237.239; 8.P.237.154; 8.P.237.157; 8.P.237.166; 8.P.237.169; 8.P.237.172; 8.P.237.175; 8.P.237.240; 8.P.237.244; 8.P.238.228; 8.P.238.229; 8.P.238.230; 8.P.238.231; 8.P.238.236; 8.P.238.237; 8.P.238.238; 8.P.238.239; 8.P.238.154; 8.P.238.157; 8.P.238.166; 8.P.238.169; 8.P.238.172; 8.P.238.175; 8.P.238.240; 8.P.238.244; 8.P.239.228; 8.P.239.229; 8.P.239.230; 8.P.239.231; 8.P.239.236; 8.P.239.237; 8.P.239.238; 8.P.239.239; 8.P.239.154; 8.P.239.157; 8.P.239.166; 8.P.239.169; 8.P.239.172; 8.P.239.175; 8.P.239.240; 8.P.239.244; 8.P.154.228; 8.P.154.229; 8.P.154.230; 8.P.154.231; 8.P.154.236; 8.P.154.237; 8.P.154.238; 8.P.154.239; 8.P.154.154; 8.P.154.157; 8.P.154.166; 8.P.154.169; 8.P.154.172; 8.P.154.175; 8.P.154.240; 8.P.154.244; 8.P.157.228; 8.P.157.229; 8.P.157.230; 8.P.157.231; 8.P.157.236; 8.P.157.237; 8.P.157.238; 8.P.157.239; 8.P.157.154; 8.P.157.157; 8.P.157.166; 8.P.157.169; 8.P.157.172; 8.P.157.175; 8.P.157.240; 8.P.157.244; 8.P.166.228; 8.P.166.229; 8.P.166.230; 8.P.166.231; 8.P.166.236; 8.P.166.237; 8.P.166.238; 8.P.166.239; 8.P.166.154; 8.P.166.157; 8.P.166.166; 8.P.166.169; 8.P.166.172; 8.P.166.175; 8.P.166.240; 8.P.166.244; 8.P.169.228; 8.P.169.229; 8.P.169.230; 8.P.169.231; 8.P.169.236; 8.P.169.237; 8.P.169.238; 8.P.169.239; 8.P.169.154; 8.P.169.157; 8.P.169.166; 8.P.169.169; 8.P.169.172; 8.P.169.175; 8.P.169.240; 8.P.169.244; 8.P.172.228; 8.P.172.229; 8.P.172.230; 8.P.172.231; 8.P.172.236; 8.P.172.237; 8.P.172.238; 8.P.172.239; 8.P.172.154; 8.P.172.157; 8.P.172.166; 8.P.172.169; 8.P.172.172; 8.P.172.175; 8.P.172.240; 8.P.172.244; 8.P.175.228; 8.P.175.229; 8.P.175.230; 8.P.175.231; 8.P.175.236; 8.P.175.237; 8.P.175.238; 8.P.175.239; 8.P.175.154; 8.P.175.157; 8.P.175.166; 8.P.175.169; 8.P.175.172; 8.P.175.175; 8.P.175.240; 8.P.175.244; 8.P.240.228; 8.P.240.229; 8.P.240.230; 8.P.240.231; 8.P.240.236; 8.P.240.237; 8.P.240.238; 8.P.240.239; 8.P.240.154; 8.P.240.157; 8.P.240.166; 8.P.240.169; 8.P.240.172; 8.P.240.175; 8.P.240.240; 8.P.240.244; 8.P.244.228; 8.P.244.229; 8.P.244.230; 8.P.244.231; 8.P.244.236; 8.P.244.237; 8.P.244.238; 8.P.244.239; 8.P.244.154; 8.P.244.157; 8.P.244.166; 8.P.244.169; 8.P.244.172; 8.P.244.175; 8.P.244.240; 8.P.244.244;

Prodrugs of 8.U

8.U.228.228; 8.U.228.229; 8.U.228.230; 8.U.228.231; 8.U.228.236; 8.U.228.237; 8.U.228.238; 8.U.228.239; 8.U.228.154; 8.U.228.157; 8.U.228.166; 8.U.228.169; 8.U.228.172; 8.U.228.175; 8.U.228.240; 8.U.228.244; 8.U.229.228; 8.U.229.229; 8.U.229.230; 8.U.229.231; 8.U.229.236; 8.U.229.237; 8.U.229.238; 8.U.229.239; 8.U.229.154; 8.U.229.157; 8.U.229.166; 8.U.229.169; 8.U.229.172; 8.U.229.175; 8.U.229.240; 8.U.229.244; 8.U.230.228; 8.U.230.229; 8.U.230.230; 8.U.230.231; 8.U.230.236; 8.U.230.237; 8.U.230.238; 8.U.230.239; 8.U.230.154; 8.U.230.157; 8.U.230.166; 8.U.230.169; 8.U.230.172; 8.U.230.175; 8.U.230.240; 8.U.230.244; 8.U.231.228; 8.U.231.229; 8.U.231.230; 8.U.231.231; 8.U.231.236; 8.U.231.237; 8.U.231.238; 8.U.231.239; 8.U.231.154; 8.U.231.157; 8.U.231.166; 8.U.231.169; 8.U.231.172; 8.U.231.175; 8.U.231.240; 8.U.231.244; 8.U.236.228; 8.U.236.229; 8.U.236.230; 8.U.236.231; 8.U.236.236; 8.U.236.237; 8.U.236.238; 8.U.236.239; 8.U.236.154; 8.U.236.157; 8.U.236.166; 8.U.236.169; 8.U.236.172; 8.U.236.175; 8.U.236.240; 8.U.236.244; 8.U.237.228; 8.U.237.229; 8.U.237.230; 8.U.237.231; 8.U.237.236; 8.U.237.237; 8.U.237.238; 8.U.237.239; 8.U.237.154; 8.U.237.157; 8.U.237.166; 8.U.237.169; 8.U.237.172; 8.U.237.175; 8.U.237.240; 8.U.237.244; 8.U.238.228; 8.U.238.229; 8.U.238.230; 8.U.238.231; 8.U.238.236; 8.U.238.237; 8.U.238.238; 8.U.238.239; 8.U.238.154; 8.U.238.157; 8.U.238.166; 8.U.238.169; 8.U.238.172; 8.U.238.175; 8.U.238.24Q; 8.U.238.244; 8.U.239.228; 8.U.239.229; 8.U.239.230; 8.U.239.231; 8.U.239.236; 8.U.239.237; 8.U.239.238; 8.U.239.239; 8.U.239.154; 8.U.239.157; 8.U.239.166; 8.U.239.169; 8.U.239.172; 8.U.239.175; 8.U.239.240; 8.U.239.244; 8.U.154.228; 8.U.154.229; 8.U.154.230; 8.U.154.231; 8.U.154.236; 8.U.154.237; 8.U.154.238; 8.U.154.239; 8.U.154.154; 8.U.154.157; 8.U.154.166; 8.U.154.169; 8.U.154.172; 8.U.154.175; 8.U.154.240; 8.U.154.244; 8.U.157.228; 8.U.157.229; 8.U.157.230; 8.U.157.231; 8.U.157.236; 8.U.157.237; 8.U.157.238;-8.U.157.239; 8.U.157.154; 8.U.157.157; 8.U.157.166; 8.U.157.169; 8.U.157.172; 8.U.157.175; 8.U.157.240; 8.U.157.244; 8.U.166.228; 8.U.166.229; 8.U.166.230; 8.U.166.231; 8.U.166.236; 8.U.166.237; 8.U.166.238; 8.U.166.239; 8.U.166.154; 8.U.166.157; 8.U.166.166; 8.U.166.169; 8.U.166.172; 8.U.166.175; 8.U.166.240; 8.U.166.244; 8.U.169.228; 8.U.169.229; 8.U.169.230; 8.U.169.231; 8.U.169.236; 8.U.169.237; 8.U.169.238; 8.U.169.239; 8.U.169.154; 8.U.169.157; 8.U.169.166; 8.U.169.169; 8.U.169.172; 8.U.169.175; 8.U.169.240; 8.U.169.244; 8.U.172.228; 8.U.172.229; 8.U.172.230; 8.U.172.231; 8.U.172.236; 8.U.172.237; 8.U.172.238; 8.U.172.239; 8.U.172.154; 8.U.172.157; 8.U.172.166; 8.U.172.169; 8.U.172.172; 8.U.172.175; 8.U.172.240; 8.U.172.244; 8.U.175.228; 8.U.175.229; 8.U.175.230; 8.U.175.231; 8.U.175.236; 8.U.175.237; 8.U.175.238; 8.U.175.239; 8.U.175.154; 8.U.175.157; 8.U.175.166; 8.U.175.169; 8.U.175.172; 8.U.175.175; 8.U.175.240; 8.U.175.244; 8.U.240.228; 8.U.240.229; 8.U.240.230; 8.U.240.231; 8.U.240.236; 8.U.240.237; 8.U.240.238; 8.U.240.239; 8.U.240.154; 8.U.240.157; 8.U.240.166; 8.U.24Q.169; 8.U.240.172; 8.U.240.175; 8.U.240.240; 8.U.240.244; 8.U.244.228; 8.U.244.229; 8.U.244.230; 8.U.244.231; 8.U.244.236; 8.U.244.237; 8.U.244.238; 8.U.244.239; 8.U.244.154; 8.U.244.157; 8.U.244.166; 8.U.244.169; 8.U.244.172; 8.U.244.175; 8.U.244.240; 8.U.244.244;

Prodrugs of 8.CD

8.CD.228.228; 8.CD.228.229; 8.CD.228.230; 8.CD.228.231; 8.CD.228.236; 8.CD.228.237; 8.CD.228.238; 8.CD.228.239; 8.CD.228.154; 8.CD.228.157; 8.CD.228.166; 8.CD.228.169; 8.CD.228.172; 8.CD.228.175; 8.CD.228.240; 8.CD.228.244; 8.CD.229.228; 8.CD.229.229; 8.CD.229.230; 8.CD.229.231; 8.CD.229.236; 8.CD.229.237; 8.CD.229.238; 8.CD.229.239; 8.CD.229.154; 8.CD.229.157; 8.CD.229.166; 8.CD.229.169; 8.CD.229.172; 8.CD.229.175; 8.CD.229.240; 8.CD.229.244; 8.CD.230.228; 8.CD.230.229; 8.CD.230.230; 8.CD.230.231; 8.CD.230.236; 8.CD.230.237; 8.CD.230.238; 8.CD.23Q.239; 8.CD.230.154; 8.CD.230.157; 8.CD.230.166; 8.CD.230.169; 8.CD.230.172; 8.CD.230.175; 8.CD.230.240; 8.CD.230.244; 8.CD.231.228; 8.CD.231.229; 8.CD.231.230; 8.CD.231.231; 8.CD.231.236; 8.CD.231.237; 8.CD.231.238; 8.CD.231.239; 8.CD.231.154; 8.CD.231.157; 8.CD.231.166; 8.CD.231.169; 8.CD.231.172; 8.CD.231.175; 8.CD.231.240; 8.CD.231.244; 8.CD.236.228; 8.CD.236.229; 8.CD.236.230; 8.CD.236.231; 8.CD.236.236; 8.CD.236.237; 8.CD.236.238; 8.CD.236.239; 8.CD.236.154; 8.CD.236.157; 8.CD.236.166; 8.CD.236.169; 8.CD.236.172; 8.CD.236.175; 8.CD.236.240; 8.CD.236.244; 8.CD.237.228; 8.CD.237.229; 8.CD.237.230; 8.CD.237.231; 8.CD.237.236; 8.CD.237.237; 8.CD.237.238; 8.CD.237.239; 8.CD.237.154; 8.CD.237.157; 8.CD.237.166; 8.CD.237.169; 8.CD.237.172; 8.CD.237.175; 8.CD.237.240; 8.CD.237.244; 8.CD.238.228; 8.CD.238.229; 8.CD.238.23Q; 8.CD.238.231; 8.CD.238.236; 8.CD.238.237; 8.CD.238.238; 8.CD.238.239; 8.CD.238.154; 8.CD.238.157; 8.CD.238.166; 8.CD.238.169; 8.CD.238.172; 8.CD.238.175; 8.CD.238.240; 8.CD.238.244; 8.CD.239.228; 8.CD.239.229; 8.CD.239.230; 8.CD.239.231; 8.CD.239.236; 8.CD.239.237; 8.CD.239.238; 8.CD.239.239; 8.CD.239.154; 8.CD-239.157; 8.CD.239.166; 8.CD.239.169; 8.CD.239.172; 8.CD.239.175; 8.CD.239.240; 8.CD.239.244; 8.CD.154.228; 8.CD.154.229; 8.CD.154.230; 8.CD.154.231; 8.CD.154.236; 8.CD.154.237; 8.CD.154.238; 8.CD.154.239; 8.CD.154.154; 8.CD.154.157; 8.CD.154.166; 8.CD.154.169; 8.CD.154.172; 8.CD.154.175; 8.CD.154.240; 8.CD.154.244; 8.CD.157.228; 8.CD.157.229; 8.CD.157.230; 8.CD.157.231; 8.CD.157.236; 8.CD.157.237; 8.CD.157.238; 8.CD.157.239; 8.CD.157.154; 8.CD.157.157; 8.CD.157.166; 8.CD.157.169; 8.CD.157.172; 8.CD.157.175; 8.CD.157.240; 8.CD.157.244; 8.CD.166.228; 8.CD.166.229; 8.CD.166.230; 8.CD.166.231; 8.CD.166.236; 8.CD.166.237; 8.CD.166.238; 8.CD.166.239; 8.CD.166.154; 8.CD.166.157; 8.CD.166.166; 8.CD.166.169; 8.CD.166.172; 8.CD.166.175; 8.CD.166.240; 8.CD.166.244; 8.CD.169.228; 8.CD.169.229; 8.CD.169.230; 8.CD.169.231; 8.CD.169.236; 8.CD.169.237; 8.CD.169.238; 8.CD.169.239; 8.CD.169.154; 8.CD.169.157; 8.CD.169.166; 8.CD.169.169; 8.CD.169.172; 8.CD.169.175; 8.CD.169.240; 8.CD.169.244; 8.CD.172.228; 8.CD.172.229; 8.CD.172.230; 8.CD.172.231; 8.CD.172.236; 8.CD.172.237; 8.CD.172.238; 8.CD.172.239; 8.CD.172.154; 8.CD.172.157; 8.CD.172.166; 8.CD.172.169; 8.CD.172.172; 8.CD.172.175; 8.CD.172.240; 8.CD.172.244; 8.CD.175.228; 8.CD.175.229; 8.CD.175.230; 8.CD.175.231; 8.CD.175.236; 8.CD.175.237; 8.CD.175.238; 8.CD.175.239; 8.CD.175.154; 8.CD.175.157; 8.CD.175.166; 8.CD.175.169; 8.CD.175.172; 8.CD.175.175; 8.CD.175.240; 8.CD.175.244; 8.CD.240.228; 8.CD.240.229; 8.CD.240.230; 8.CD.240.231; 8.CD.240.236; 8.CD.240.237; 8.CD.240.238; 8.CD.240.239; 8.CD.240.154; 8.CD.240.157; 8.CD.240.166; 8.CD.240.169; 8.CD.240.172; 8.CD.240.175; 8.CD.240.240; 8.CD.240.244; 8.CD.244.228; 8.CD.244.229; 8.CD.244.230; 8.CD.244.231; 8.CD.244.236; 8.CD.244.237; 8.CD.244.238; 8.CD.244.239; 8.CD.244.154; 8.CD.244.157; 8.CD.244.166; 8.CD.244.169; 8.CD.244.172; 8.CD.244.175; 8.CP.244.240; 8.CD.244.244;

Prodrugs of 8.EB

8.EB.228.228; 8.EB.228.229; 8.EB.228.230; 8.EB.228.231; 8.EB.228.236; 8.EB.228.237; 8.EB.228.238; 8.EB.228.239; 8.EB.228.154; 8.EB.228.157; 8.EB.228.166; 8.EB.228.169; 8.EB.228.172; 8.EB.228.175; 8.EB.228.240; 8.EB.228.244; 8.EB.229.228; 8.EB.229.229; 8.EB.229.230; 8.EB.229.231; 8.EB.229.236; 8.EB.229.237; 8.EB.229.238; 8.EB.229.239; 8.EB.229.154; 8.EB.229.157; 8.EB.229.166; 8.EB.229.169; 8.EB.229.172; 8.EB.229.175; 8.EB.229.240; 8.EB.229.244; 8.EB.230.228; 8.EB.230.229; 8.EB.230.230; 8.EB.230.231; 8.EB.230.236; 8.EB.230.237; 8.EB.230.238; 8.EB.230.239; 8.EB.230.154; 8.EB.23Q.157; 8.EB.230.166; 8.EB.230.169; 8.EB.230.172; 8.EB.230.175; 8.EB.230.240; 8.EB.230.244; 8.EB.231.228; 8.EB.231.229; 8.EB.231.230; 8.EB.231.231; 8.EB.231.236; 8.EB.231.237; 8.EB.231.238; 8.EB.231.239; 8.EB.231.154; 8.EB.231.157; 8.EB.231.166; 8.EB.231.169; 8.EB.231.172; 8.EB.231.175; 8.EB.231.240; 8.EB.231.244; 8.EB.236.228; 8.EB.236.229; 8.EB.236.230; 8.EB.236.231; 8.EB.236.236; 8.EB.236.237; 8.EB.236.238; 8.EB.236.239; 8.EB.236.154; 8.EB.236.157; 8.EB.236.166; 8.EB.236.169; 8.EB.236.172; 8.EB.236.175; 8.EB.236.240; 8.EB.236.244; 8.EB.237.228; 8.EB.237.229; 8.EB.237.230; 8.EB.237.231; 8.EB.237.236; 8.EB.237.237; 8.EB.237.238; 8.EB.237.239; 8.EB.237.154; 8.EB.237.157; 8.EB.237.166; 8.EB.237.169; 8.EB.237.172; 8.EB.237.175; 8.EB.237.240; 8.EB.237.244; 8.EB.238.228; 8.EB.238.229; 8.EB.238.230; 8.EB.238.231; 8.EB.238.236; 8.EB.238.237; 8.EB.238.238; 8.EB.238.239; 8.EB.238.154; 8.EB.238.157; 8.EB.238.166; 8.EB.238.169; 8.EB.238.172; 8.EB.238.175; 8.EB.238.240; 8.EB.238.244; 8.EB.239.228; 8.EB.239.229; 8.EB.239.230; 8.EB.239.231; 8.EB.239.236; 8.EB.239.237; 8.EB.239.238; 8.EB.239.239; 8.EB.239.154; 8.EB.239.157; 8.EB.239.166; 8.EB.239.169; 8.EB.239.172; 8.EB.239.175; 8.EB.239.240; 8.EB.239.244; 8.EB.154.228; 8.EB.154.229; 8.EB.154.230; 8.EB.154.231; 8.EB.154.236; 8.EB.154.237; 8.EB.154.238; 8.EB.154.239; 8.EB.154.154; 8.EB.154.157; 8.EB.154.166; 8.EB.154.169; 8.EB.154.172; 8.EB.154.175; 8.EB.154.240; 8.EB.154.244; 8.EB.157.228; 8.EB.157.229; 8.EB.157.230; 8.EB.157.231; 8.EB.157.236; 8.EB.157.237; 8.EB.157.238; 8.EB.157.239; 8.EB.157.154; 8.EB.157.157; 8.EB.157.166; 8.EB.157.169; 8.EB.157.172; 8.EB.157.175; 8.EB.157.240; 8.EB.157.244; 8.EB.166.228; 8.EB.166.229; 8.EB.166.230; 8.EB.166.231; 8.EB.166.236; 8.EB.166.237; 8.EB.166.238; 8.EB.166.239; 8.EB.166.154; 8.EB.166.157; 8.EB.166.166; 8.EB.166.169; 8.EB.166.172; 8.EB.166.175; 8.EB.166.240; 8.EB.166.244; 8.EB.169.228; 8.EB.169.229; 8.EB.169.230; 8.EB.169.231; 8.EB.169.236; 8.EB.169.237; 8.EB.169.238; 8.EB.169.239; 8.EB.169.154; 8.EB.169.157; 8.EB.169.166; 8.EB.169.169; 8.EB.169.172; 8.EB.169.175; 8.EB.169.240; 8.EB.169.244; 8.EB.172.228; 8.EB.172.229; 8.EB.172.230; 8.EB.172.231; 8.EB.172.236; 8.EB.172.237; 8.EB.172.238; 8.EB.172.239; 8.EB.172.154; 8.EB.172.157; 8.EB.172.166; 8.EB.172.169; 8.EB.172.172; 8.EB.172.175; 8.EB.172.240; 8.EB.172.244; 8.EB.175.228; 8.EB.175.229; 8.EB.175.230; 8.EB.175.231; 8.EB.175.236; 8.EB.175.237; 8.EB.175.238; 8.EB.175.239; 8.EB.175.154; 8.EB.175.157; 8.EB.175.166; 8.EB.175.169; 8.EB.175.172; 8.EB.175.175; 8.EB.175.240; 8.EB.175.244; 8.EB.240.228; 8.EB.240.229; 8.EB.240.230; 8.EB.240.231; 8.EB.240.236; 8.EB.240.237; 8.EB.24Q.238; 8.EB.240.239; 8.EB.240.154; 8.EB.240.157; 8.EB.240.166; 8.EB.24Q.169; 8.EB.240.172; 8.EB.240.175; 8.EB.240.240; 8.EB.240.244; 8.EB.244.228; 8.EB.244.229; 8.EB.244.230; 8.EB.244.231; 8.EB.244.236; 8.EB.244.237; 8.EB.244.238; 8.EB.244.239; 8.EB.244.154; 8.EB.244.157; 8.EB.244.166; 8.EB.244.169; 8.EB.244.172; 8.EB.244.175; 8.EB.244.240; 8.EB.244.244;

Prodrugs of 9.B

9.B.228.228; 9.B.228.229; 9.B.228.230; 9.B.228.231; 9.B.228.236; 9.B.228.237; 9.B.228.238; 9.B.228.239; 9.B.228.154; 9.B.228.157; 9.B.228.166; 9.B.228.169; 9.B.228.172; 9.B.228.175; 9.B.228.240; 9.B.228.244; 9.B.229.228; 9.B.229.229; 9.B.229.230; 9.B.229.231; 9.B.229.236; 9.B.229.237; 9.B.229.238; 9.B.229.239; 9.B.229.154; 9.B.229.157; 9.B.229.166; 9.B.229.169; 9.B.229.172; 9.B.229.175; 9.B.229.240; 9.B.229.244; 9.B.230.228; 9.B.230.229; 9.B.230.230; 9.B.230.231; 9.B.230.236; 9.B.230.237; 9.B.230.238; 9.B.230.239; 9.B.230.154; 9.B.230.157; 9.B.230.166; 9.B.230.169; 9.B.230.172; 9.B.230.175; 9.B.230.240; 9.B.230.244; 9.B.231.228; 9.B.231.229; 9.B.231.230; 9.B.231.231; 9.B.231.236; 9.B.231.237; 9.B.231.238; 9.B.231.239; 9.B.231.154; 9.B.231.157; 9.B.231.166; 9.B.231.169; 9.B.23U72; 9.B.231.175; 9.B.231.240; 9.B.231.244; 9.B.236.228; 9.B.236.229; 9.B.236.230; 9.B.236.231; 9.B.236.236; 9.B.236.237; 9.B.236.238; 9.B.236.239; 9.B.236.154; 9.B.236.157; 9.B.236.166; 9.B.236.169; 9.B.236.172; 9.B.236.175; 9.B.236.240; 9.B.236.244; 9.B.237.228; 9.B.237.229; 9.B.237.230; 9.B.237.231; 9.B.237.236; 9.B.237.237; 9.B.237.238; 9.B.237.239; 9.B.237.154; 9.B.237.157; 9.B.237.166; 9.B.237.169; 9.B.237.172; 9.B.237.175; 9.B.237.240; 9.B.237.244; 9.B.238.228; 9.B.238.229; 9.B.238.230; 9.B.238.231; 9.B.238.236; 9.B.238.237; 9.B.238.238; 9.B.238.239; 9.B.238.154; 9.B.238.157; 9.B.238.166; 9.B.238.169; 9.B.238.172; 9.B.238.175; 9.B.238.240; 9.B.238.244; 9.B.239.228; 9.B.239.229; 9.B.239.230; 9.B.239.231; 9.B-239.236; 9.B.239.237; 9.B.239.238; 9.B.239.239; 9.B.239.154; 9.B.239.157; 9.B.239.166; 9.B.239.169; 9.B.239.172; 9.B.239.175; 9.B.239.240; 9.B.239.244; 9.B.154.228; 9.B.154.229; 9.B.154.230; 9.B.154.231; 9.B.154.236; 9.B.154.237; 9.B.154.238; 9.B.154.239; 9.B.154.154; 9.B.154.157; 9.B.154.166; 9.B.154.169; 9.B.154.172; 9.B.154.175; 9.B.154.240; 9.B.154.244; 9.B.157.228; 9.B.157.229; 9.B.157.230; 9.B.157.231; 9.B.157.236; 9.B.157.237; 9.B.157.238; 9.B.157.239; 9.B.157.154; 9.B.157.157; 9.B.157.166; 9.B.157.169; 9.B.157.172; 9.B.157.175; 9.B.157.240; 9.B.157.244; 9.B.166.228; 9.B.166.229; 9.B.166.230; 9.B.166.231; 9.B.166.236; 9.B.166.237; 9.B.166.238; 9.B.166.239; 9.B.166.154; 9.B.166.157; 9.B.166.166; 9.B.166.169; 9.B..166.172; 9.B.166.175; 9.B.166.240; 9.B.166.244; 9.B.169.228; 9.B.169.229; 9.B.169.230; 9.B.169.231; 9.B.169.236; 9.B.169.237; 9.B.169.238; 9.B.169.239; 9.B.169.154; 9.B.169.157; 9.B.169.166; 9.B.169.169; 9.B.169.172; 9.B.169.175; 9.B.169.240; 9.B.169.244; 9.B.172.228; 9.B.172.229; 9.B.172.230; 9.B.172.231; 9.B.172.236; 9.B.172.237; 9.B.172.238; 9.B.172.239; 9.B.172.154; 9.B.172.157; 9.B.172.166; 9.B.172.169; 9.B.172.172; 9.B.172.175; 9.B.172.240; 9.B.172.244; 9.B.175.228; 9.B.175.229; 9.B.175.230; 9.B.175.231; 9.B.175.236; 9.B.175.237; 9.B.175.238; 9.B.175.239; 9.B.175.154; 9.B.175.157; 9.B.175.166; 9.B.175.169; 9.B.175.172; 9.B.175.175; 9.B.175.240; 9.B.175.244; 9.B.24Q.228; 9.B.240.229; 9.B.240.230; 9.B.240.231; 9.B.240.236; 9.B.240.237; 9.B.240.238; 9.B.24Q.239; 9.B.240.154; 9.B.240.157; 9.B.240.166; 9.B.240.169; 9.B.24Q.172; 9.B.240.175; 9.B.240.240; 9.B.240.244; 9.B.244.228; 9.B.244.229; 9.B.244.23Q; 9.B.244.231; 9.B.244.236; 9.B.244.237; 9.B.244.238; 9.B.244.239; 9.B.244.154; 9.B.244.157; 9.B.244.166; 9.B.244.169; 9.B.244.172; 9.B.244.175; 9.B.244.240; 9.B.244.244;

Prodrugs of 9.D

9.D.228.228; 9.D.228.229; 9.D.228.230; 9.D.228.231; 9.D.228.236; 9.D.228.237; 9.D.228.238; 9.D.228.239; 9.D.228.154; 9.D.228.157; 9.D.228.166; 9.D.228.169; 9.D.228.172; 9.D.228.175; 9.D.228.240; 9.D.228.244; 9.D.229.228; 9.D.229.229; 9.D.229.230; 9.D.229.231; 9.D.229.236; 9.D.229.237; 9.D.229.238; 9.D.229.239; 9.D.229.154; 9.D.229.157; 9.D.229.166; 9.D.229.169; 9.D.229.172; 9.D.229.175; 9.D.229.240; 9.D.229.244; 9.D.230.228; 9.D.230.229; 9.D.230.230; 9.D.230.231; 9.D.230.236; 9.D.230.237; 9.D.230.238; 9.D.230.239; 9.D.230.154; 9.D.230.157; 9.D.230.166; 9.D.23Q.169; 9.D.230.172; 9.D.230.175; 9.D.230.240; 9.D.230.244; 9.D.231.228; 9.D.231.229; 9.D.231.230; 9.D.231.231; 9.D.231.236; 9.D.231.237; 9.D.231.238; 9.D.231.239; 9.D.231.154; 9.D.231.157; 9.D.231.166; 9.D.231.169; 9.D.231.172; 9.D.231.175; 9.D.231.240; 9.D.231.244; 9.D.236.228; 9.D.236.229; 9.D.236.230; 9.D.236.231; 9.D.236.236; 9.D.236.237; 9.D.236.238; 9.D.236.239; 9.D.236.154; 9.D.236.157; 9.D.236.166; 9.D.236.169; 9.D.236.172; 9.D.236.175; 9.D.236.240; 9.D.236.244; 9.D.237.228; 9.D.237.229; 9.D.237.230; 9.D.237.231; 9.D.237.236; 9.D.237.237; 9.D.237.238; 9.D.237.239; 9.D.237.154; 9.D.237.157; 9.D.237.166; 9.D.237.169; 9.D.237.172; 9.D.237.175; 9.D.237.240; 9.D.237.244; 9.D.238.228; 9.D.238.229; 9.D.238.230; 9.D.238.231; 9.D.238.236; 9.D.238.237; 9.D.238.238; 9.D.238.239; 9.D.238.154; 9.D.238.157; 9.D.238.166; 9.D.238.169; 9.D.238.172; 9.D.238.175; 9.D.238.240; 9.D.238.244; 9.D.239.228; 9.D.239.229; 9.D.239.230; 9.D.239.231; 9.D.239.236; 9.D.239.237; 9.D.239.238; 9.D.239.239; 9.D.239.154; 9.D.239.157; 9.D.239.166; 9.D.239.169; 9.D.239.172; 9.D.239.175; 9.D.239.240; 9.D.239.244; 9.D.154.228; 9.D.154.229; 9.D.154.230; 9.D.154.231; 9.D.154.236; 9.D.154.237; 9.D.154.238; 9.D.154.239; 9.D.154.154; 9.D.154.157; 9.D.154.166; 9.D.154.169; 9.D.154.172; 9.D.154.175; 9.D.154.240; 9.D.154.244; 9.D.157.228; 9.D.157.229; 9.D.157.230; 9.D.157.231; 9.D.157.236; 9.D.157.237; 9.D.157.238; 9.D.157.239; 9.D.157.154; 9.D.157.157; 9.D.157.166; 9.D.157.169; 9.D.157.172; 9.D.157.175; 9.D.157.240; 9.D.157.244; 9.D.166.228; 9.D.166.229; 9.D.166.230; 9.D.166.231; 9.D.166.236; 9.D.166.237; 9.D.166.238; 9.D.166.239; 9.D.166.154; 9.D.166.157; 9.D.166.166; 9.D.166.169; 9.D.166.172; 9.D.166.175; 9.D.166.240; 9.D.166.244; 9.D.169.228; 9.D.169.229; 9.D.169.230; 9.D.169.231; 9.D.169.236; 9.D.169.237; 9.D.169.238; 9.D.169.239; 9.D.169.154; 9.D.169.157; 9.D.169.166; 9.D.169.169; 9.D.169.172; 9.D.169.175; 9.D.169.240; 9.D.169.244; 9.D.172.228; 9.D.172.229; 9.D.172.230; 9.D.172.231; 9.D.172.236; 9.D.172.237; 9.D.172.238; 9.D.172.239; 9.D.172.154; 9.D.172.157; 9.D.172.166; 9.D.172.169; 9.D.172.172; 9.D.172.175; 9.D.172.240; 9.D.172.244; 9.D.175.228; 9.D.175.229; 9.D.175.230; 9.D.175.231; 9.D.175.236; 9.D.175.237; 9.D.175.238; 9.D.175.239; 9.D.175.154; 9.D.175.157; 9.D.175.166; 9.D.175.169; 9.D.175.172; 9.D.175.175; 9.D.175.240; 9.D.175.244; 9.D.240.228; 9.D.240.229; 9.D.240.230; 9.D.240.231; 9.D.240.236; 9.D.240.237; 9.D.240.238; 9.D.240.239; 9.D.240.154; 9.D.240.157; 9.D.240.166; 9.D.240.169; 9.D.240.172; 9.D.24Q.175; 9.D.240.240; 9.D.240.244; 9.D.244.228; 9.D.244.229; 9.D.244.230; 9.D.244.231; 9.D.244.236; 9.D.244.237; 9.D.244.238; 9.D.244.239; 9.D.244.154; 9.D.244.157; 9.D.244.166; 9.D.244.169; 9.D.244.172; 9.D.244.175; 9.D.244.240; 9.D.244.244;

Prodrugs of 9.AB

9.AB.228.228; 9.AB.228.229; 9.AB.228.230; 9.AB.228.231; 9.AB.228.236; 9.AB.228.237; 9.AB.228.238; 9.AB.228.239; 9.AB.228.154; 9.AB.228.157; 9.AB.228.166; 9.AB.228.169; 9.AB.228.172; 9.AB.228.175; 9.AB.228.240; 9.AB.228.244; 9.AB.229.228; 9.AB.229.229; 9.AB.229.230; 9.AB.229.231; 9.AB.229.236; 9.AB.229.237; 9.AB.229.238; 9.AB.229.239; 9.AB.229.154; 9.AB.229.157; 9.AB.229.166; 9.AB.229.169; 9.AB.229.172; 9.AB.229.175; 9.AB.229.240; 9.AB.229.244; 9.AB.230.228; 9.AB.230.229; 9.AB.230.230; 9.AB.230.231; 9.AB.23Q.236; 9.AB.230.237; 9.AB.230.238; 9.AB.230.239; 9.AB.230.154; 9.AB.230.157; 9.AB.230.166; 9.AB.230.169; 9.AB.230.172; 9.AB.230.175; 9.AB.230.240; 9.AB.230.244; 9.AB.231.228; 9.AB.231.229; 9AB.231.230; 9.AB.231.231; 9.AB.231.236; 9.AB.231.237; 9.AB.231.238; 9AB.231.239; 9.AB.231.154; 9.AB.231.157; 9.AB.231.166; 9.AB.231.169; 9.AB.231.172; 9.AB.231.175; 9.AB.231.240; 9.AB.231.244; 9.AB.236.228; 9.AB.236.229; 9.AB.236.230; 9.AB.236.231; 9.AB.236.236; 9.AB.236.237; 9 AB.236.238; 9.AB.236.239; 9.AB.236.154; 9.AB.236.157; 9.AB.236.166; 9 AB.236.169; 9.AB.236.172; 9.AB.236.175; 9.AB.236.240; 9.AB.236.244; 9 AB.237.228; 9.AB.237.229; 9.AB.237.230; 9.AB.237.231; 9.AB.237.236; 9 AB.237.237; 9.AB.237.238; 9.AB.237.239; 9.AB.237.154; 9.AB.237.157; 9 AB.237.166; 9.AB.237.169; 9 AB.237.172; 9.AB.237.175; 9.AB.237.240; 9 AB.237.244; 9.AB.238.228; 9.AB.238.229; 9.AB.238.230; 9.AB.238.231; 9 AB.238.236; 9.AB.238.237; 9.AB.238.238; 9.AB.238.239; 9.AB.238.154; 9 AB.238.157; 9.AB.238.166; 9.AB.238.169; 9.AB.238.172; 9.AB.238.175; 9 AB.238.240; 9.AB.238.244; 9.AB.239.228; 9.AB.239.229; 9.AB.239.230; 9 AB.239.231; 9.AB.239.236; 9.AB.239.237; 9.AB.239.238; 9.AB.239.239; 9 AB.239.154; 9.AB.239.157; 9 AB.239.166; 9.AB.239.169; 9.AB.239.172; 9 AB.239.175; 9.AB.239.240; 9.AB.239.244; 9.AB.154.228; 9.AB.154.229; 9.AB.154.230; 9.AB.154.231; 9.AB.154.236; 9.AB.154.237; 9.AB.154.238; 9 AB.154.239; 9.AB.154.154; 9.AB.154.157; 9.AB.154.166; 9.AB.154.169; 9 AB.154.172; 9.AB.154.175; 9.AB.154.240; 9.AB.154.244; 9.AB.157.228; 9 AB.157.229; 9.AB.157.230; 9.AB.157.231; 9.AB.157.236; 9.AB.157.237; 9 AB.157.238; 9.AB.157.239; 9.AB.157.154; 9.AB.157.157; 9.AB.157.166; 9 AB.157.169; 9.AB.157.172; 9 AB.157.175; 9.AB.157.240; 9.AB.157.244; 9 AB.166.228; 9.AB.166.229; 9.AB.166.230; 9.AB.166.231; 9.AB.166.236; 9 AB.166.237; 9.AB.166.238; 9.AB.166.239; 9.AB.166.154; 9.AB.166.157; 9 AB.166.166; 9.AB.166.169; 9.AB.166.172; 9.AB.166.175; 9.AB.166.240; 9 AB.166.244; 9.AB.169.228; 9.AB.169.229; 9.AB.169.230; 9.AB.169.231; 9 AB.169.236; 9.AB.169.237; 9.AB.169.238; 9.AB.169.239; 9.AB.169.154; 9.AB.169.157; 9.AB.169.166; 9.AB.169.169; 9.AB.169.172; 9.AB.169.175; 9.AB.169.240; 9.AB.169.244; 9.AB.172.228; 9.AB.172.229; 9.AB.172.230; 9.AB.172.231; 9.AB.172.236; 9.AB.172.237; 9.AB.172.238; 9.AB.172.239; 9.AB.172.154; 9.AB.172.157; 9.AB.172.166; 9.AB.172.169; 9.AB.172.172; 9.AB.172.175; 9.AB.172.240; 9.AB.172.244; 9.AB.175.228; 9.AB.175.229; 9.AB.175.230; 9.AB.175.231; 9.AB.175.236; 9.AB.175.237; 9.AB.175.238; 9.AB.175.239; 9.AB.175.154; 9.AB.175.157; 9.AB.175.166; 9.AB.175.169; 9.AB.175.172; 9.AB.175.175; 9.AB.175.240; 9.AB.175.244; 9.AB.240.228; 9.AB-240.229; 9.AB.240.230; 9.AB.240.231; 9.AB.240.236; 9.AB.240.237; 9.AB.240.238; 9.AB.240.239; 9.AB.240.154; 9.AB.240.157; 9.AB.240.166; 9.AB.240.169; 9.AB.24Q.172; 9.AB.240.175; 9.AB.240.240; 9.AB.240.244; 9.AB.244.228; 9.AB.244.229; 9.AB.244.230; 9.AB.244.231; 9.AB.244.236; 9.AB.244.237; 9.AB.244.238; 9.AB.244.239; 9.AB.244.154; 9.AB.244.157; 9.AB.244.166; 9.AB.244.169; 9.AB.244.172; 9.AB.244.175; 9.AB.244.240; 9.AB.244.244;

Prodrugs of 9.BI

9÷BI.228.228; 9.BI.228.229; 9.BI.228.230; 9.BI.228.231; 9.BI.228.236; 9.BI.228.237; 9.BI.228.238; 9.BI.228.239; 9.BI.228.154; 9.BI.228.157; 9.BI.228.166; 9.BI.228.169; 9.BI.228.172; 9.BI.228.175; 9.BI.228.240; 9.BI.228.244; 9.BI.229.228; 9.BI.229.229; 9.BI.229.230; 9.BI.229.231; 9.BI.229.236; 9.BI.229.237; 9.BI.229.238; 9.BI.229.239; 9.BI.229.154; 9.BI.229.157; 9.BI.229.166; 9.BI.229.169; 9.BL229.172; 9.BI.229.175; 9.BI.229.240; 9.BL229.244; 9.BI.230.228; 9.BI.230.229; 9.BI.230.230; 9.BI.230.231; 9.BI.230.236; 9.BI.230.237; 9.BI.230.238; 9.BI.230.239; 9.BI.230.154; 9.BI.230.157; 9.BI.230.166; 9.BI.23Q.169; 9.BI.230.172; 9.BI.23Q.175; 9.BL230.240; 9.BI.230.244; 9.BI.231.228; 9.BI.231.229; 9.BI.231.230; 9.BI.231.231; 9.BI.231.236; 9.BI.231.237; 9.BI.231.238; 9.BL231.239; 9.BI.231.154; 9.BL231.157; 9.BI.231.166; 9.BI.231.169; 9.BI.231.172; 9.BI.231.175; 9.BI.231.240; 9.BL231.244; 9.BI.236.228; 9.BI.236.229; 9.BI.236.230; 9.BI.236.231; 9.BI.236.236; 9.BI.236.237; 9.BI.236.238; 9.BI.236.239; 9.BI.236.154; 9.BI.236.157; 9.BI.236.166; 9.BI.236.169; 9.BL236.172; 9.BI.236.175; 9.BI.236.240; 9.BI.236.244; 9.BI.237.228; 9.BI-237.229; 9.BI.237.230; 9.BI.237.231; 9.BI.237.236; 9.BI.237.237; 9.BI.237.238; 9.BI.237.239; 9.BI.237.154; 9.BI.237.157; 9.BI.237.166; 9.BI.237.169; 9.BI.237.172; 9.BI.237.175; 9.BI.237.240; 9.BI.237.244; 9.BI.238.228; 9.BI.238.229; 9.BI.238.230; 9.BI.238.231; 9.BI.238.236; 9.BI.238.237; 9.BI.238.238; 9.BI.238.239; 9.BI.238.154; 9.BI.238.157; 9.BI.238.166; 9.BI.238.169; 9.BI.238.172; 9.BI.238.175; 9.BI.238.240; 9.BI.238.244; 9.BI.239.228; 9.BI.239.229; 9.BI.239.230; 9.BI.239.231; 9.BI.239.236; 9.BI.239.237; 9.BI.239.238; 9.BI.239.239; 9.BI.239.154; 9.BI.239.157; 9.BI.239.166; 9.BI.239.169; 9.BI.239.172; 9.BI.239.175; 9.BI.239.240; 9.BI.239.244; 9.BL154.228; 9.BI.154.229; 9.BI.154.230; 9.BI.154.231; 9.BI.154.236; 9.BI.154.237; 9.BI.154.238; 9.BI.154.239; 9.BI.154.154; 9.BI.154.157; 9.BI.154.166; 9.BI.154.169; 9.BI.154.172; 9.BI.154.175; 9.BI.154.240; 9.BI.154.244; 9.BI.157.228; 9.BI.157.229; 9.BI.157.230; 9.BI.157.231; 9.BI.157.236; 9.BI.157.237; 9.BI.157.238; 9.BI.157.239; 9.BI.157.154; 9.BI.157.157; 9.BL157.166; 9.BI.157.169; 9.BI.157.172; 9.BI.157.175; 9.BI.157.240; 9.BI.157.244; 9.BI.166.228; 9.BI.166.229; 9.BI.166.230; 9.BI.166.231; 9.BI.166.236; 9.BI.166.237; 9.BI.166.238; 9.BI.166.239; 9.BI.166.154; 9.BI.166.157; 9.BI.166.166; 9.BI.166.169; 9.BI.166.172; 9.BL166.175; 9.BI.166.240; 9.BI.166.244; 9.BI.169.228; 9.BI.169.229; 9.BI.169.230; 9.BI.169.231; 9.BI.169.236; 9.BI.169.237; 9.BI.169.238; 9.BI.169.239; 9.BI.169.154; 9.BI.169.157; 9.BI.169.166; 9.BI.169.169; 9.BI.169.172; 9.BI.169.175; 9.BI.169.240; 9.BI.169.244; 9.BI.172.228; 9.BI.172.229; 9.BI.172.230; 9.BI.172.231; 9.BI.172.236; 9.BI.172.237; 9.BI.172.238; 9.BI.172.239; 9.BI.172.154; 9.BI.172.157; 9.BI.172.166; 9.BI.172.169; 9.BI.172.172; 9.BI.172.175; 9.BI.172.240; 9.BI.172.244; 9.BI.175.228; 9.BI.175.229; 9.BI.175.230; 9.BI.175.231; 9.BI.175.236; 9.BI.175.237; 9.BL175.238; 9.BI.175.239; 9.BI.175.154; 9.BI.175.157; 9.BI.175.166; 9.BI.175.169; 9.BI.175.172; 9.BI.175.175; 9.BI.175.240; 9.BI.175.244; 9.BI.240.228; 9.BI.240.229; 9.BI.240.230; 9.BI.240.231; 9.BI.240.236; 9.BI.240.237; 9.BI.240.238; 9.BI.240.239; 9.BI.240.154; 9.BI.240.157; 9.BI.240.166; 9.BI.240.169; 9.BL240.172; 9.BI.240.175; 9.BI.240.240; 9.BI.240.244; 9.BI.244.228; 9.BI.244.229; 9.BI.244.230; 9.BI.244.231; 9.BI.244.236; 9.BI.244.237; 9.BI.244.238; 9.BI.244.239; 9.BI.244.154; 9.BI.244.157; 9.BI.244.166; 9.BI.244.169; 9.BI.244.172; 9.BI.244.175; 9.BI.244.240; 9.BI.244.244;

Prodrugs of 9.1

9.1.228.228; 9.1.228.229; 9.1.228.230; 9.1.228.231; 9.1.228.236; 9.1.228.237; 9.1.228.238; 9.1.228.239; 9.1.228.154; 9.1.228.157; 9.1.228.166; 9.1.228.169; 9.1.228.172; 9.1.228.175; 9.1.228.240; 9.1.228.244; 9.1.229.228; 9.1.229.229; 9.1.229.230; 9.1.229.231; 9.1.229.236; 9.1.229.237; 9.1.229.238; 9.1.229.239; 9.1.229.154; 9.1.229.157; 9.1.229.166; 9.1.229.169; 9.1.229.172; 9.1.229.175; 9.1.229.240; 9.1.229.244; 9.1.230.228; 9.1.230.229; 9.1.230.230; 9.1.230.231; 9.1.230.236; 9.1.230.237; 9.1.230.238; 9.1.230.239; 9.1.230.154; 9.1.230.157; 9.1.230.166; 9.1.230.169; 9.1.230.172; 9.1.230.175; 9.1.230.240; 9.1.230.244; 9.1.231.228; 9.1.231.229; 9.1.231.230; 9.1.231.231; 9.1.231.236; 9.1.231.237; 9.1.231.238; 9.1.231.239; 9.1.231.154; 9.1.231.157; 9.1.231.166; 9.1.231.169; 9.1.231.172; 9.1.231.175; 9.1.231.240; 9.1.231.244; 9.1.236.228; 9.1.236.229; 9.1.236.230; 9.1.236.231; 9.1.236.236; 9.1.236.237; 9.1.236.238; 9.1.236.239; 9.1.236.154; 9.1.236.157; 9.1.236.166; 9.1.236.169; 9.1.236.172; 9.1.236.175; 9.1.236.240; 9.1.236.244; 9.1.237.228; 9.1.237.229; 9.1.237.230; 9.1.237.231; 9.1.237.236; 9.1.237.237; 9.1.237.238; 9.1.237.239; 9.1.237.154; 9.1.237.157; 9.1.237.166; 9.1.237.169; 9.1.237.172; 9.1.237.175; 9.1.237.240; 9.1.237.244; 9.1.238.228; 9.1.238.229; 9.1.238.230; 9.1.238.231; 9.1.238.236; 9.1.238.237; 9.1.238.238; 9.1.238.239; 9.1.238.154; 9.1.238.157; 9.1.238.166; 9.1.238.169; 9.1.238.172; 9.1.238.175; 9.1.238.240; 9.1.238.244; 9.1.239.228; 9.1.239.229; 9.1.239.230; 9.1.239.231; 9.1.239.236; 9.1.239.237; 9.1.239.238; 9.1.239.239; 9.1.239.154; 9.1.239.157; 9.1.239.166; 9.1.239.169; 9.1.239.172; 9.1.239.175; 9.1.239.240; 9.1.239.244; 9.1.154.228; 9.1.154.229; 9.1.154.230; 9.1.154.231; 9.1.154.236; 9.1.154.237; 9.1.154.238; 9.1.154.239; 9.1.154.154; 9.1.154.157; 9.1.154.166; 9.1.154.169; 9.1.154.172; 9.1.154.175; 9.1.154.240; 9.1.154.244; 9.1.157.228; 9.1.157.229; 9.1.157.230; 9.1.157.231; 9.1.157.236; 9.1.157.237; 9.1.157.238; 9.1.157.239; 9.1.157.154; 9.1.157.157; 9.1.157.166; 9.1.157.169; 9.1.157.172; 9.1.157.175; 9.1.157.240; 9.1.157.244; 9.1.166.228; 9.1.166.229; 9.1.166.230; 9.1.166.231; 9.1.166.236; 9.1.166.237; 9.1.166.238; 9.1.166.239; 9.1.166.154; 9.1.166.157; 9.1.166.166; 9.1.166.169; 9.1.166.172; 9.1.166.175; 9.1.166.240; 9.1.166.244; 9.1.169.228; 9.1.169.229; 9.1.169.230; 9.1.169.231; 9.1.169.236; 9.1.169.237; 9.1.169.238; 9.1.169.239; 9.1.169.154; 9.1.169.157; 9.1.169.166; 9.1.169.169; 9.1.169.172; 9.1.169.175; 9.1.169.240; 9.1.169.244; 9.1.172.228; 9.1.172.229; 9.1.172.230; 9.1.172.231; 9.1.172.236; 9.1.172.237; 9.1.172.238; 9.1.172.239; 9.1.172.154; 9.1.172.157; 9.1.172.166; 9.1.172.169; 9.1.172.172; 9.1.172.175; 9.1.172.240; 9.1.172.244; 9.1.175.228; 9.1.175.229; 9.1.175.230; 9.1.175.231; 9.1.175.236; 9.1.175.237; 9.1.175.238; 9.1.175.239; 9.1.175.154; 9.1.175.157; 9.1.175.166; 9.1.175.169; 9.1.175.172; 9.1.175.175; 9.1.175.240; 9.1.175.244; 9.1.240.228; 9.1.240.229; 9.1.240.230; 9.1.240.231; 9.1.240.236; 9.1.240.237; 9.1.240.238; 9.1.240.239; 9.1.240.154; 9.1.240.157; 9.1.240.166; 9.1.240.169; 9.1.240.172; 9.1.240.175; 9.1.240.240; 9.1.240.244; 9.1.244.228; 9.1.244.229; 9.1.244.230; 9.1.244.231; 9.1.244.236; 9.1.244.237; 9.1.244.238; 9.1.244.239; 9.1.244.154; 9.1.244.157; 9.1.244.166; 9.1.244.169; 9.1.244.172; 9.1.244.175; 9.1.244.240; 9.1.244.244;

Prodrugs of 9.T

9J.228.228; 9.J.228.229; 9.J.228.230; 9.J.228.231; 9.J.228.236; 9.J.228.237; 9.J.228.238; 9.J.228.239; 9.J.228.154; 9.J.228.157; 9.J.228.166; 9.J.228.169; 9.J.228.172; 9J.228.175; 9.J.228.240; 9J.228.244; 9 J.229.228; 9 J.229.229; 9J.229.230; 9.J.229.231; 9 J.229.236; 9.J.229.237; 9J.229.238; 9J.229.239; 9 J.229.154; 9 J.229.157; 9 J.229.166; 9J.229.169; 9 J.229.172; 9 J.229.175; 9 J.229.240; 9 J.229.244; 9 J.230.228; 9.J.230.229; 9J.230.230; 9 J.230.231; 9J.230.236; 9 J.230.237; 9J.230.238; 9 J.230.239; 9J.230.154; 9J.230.157; 9 J.230.166; 9 J.230.169; 9 J.230.172; 9 J.230.175; 9.J.230.240; 9 J.230.244; 9J.231.228; 9J.231.229; 9J.231.230; 9 J.231.231; 9J.231.236; 9J.231.237; 9J.231.238; 9J.231.239; 9J.231.154; 9 J.231.157; 9J.231.166; 9 J.231.169; 9J.231.172; 9J.231.175; 9J.231.240; 9J.231.244; 9J.236.228; 9J.236.229; 9J.236.230; 9J.236.231; 9J.236.236; 9J.236.237; 9J.236.238; 9J.236.239; 9 J.236.154; 9J.236.157; 9 J.236.166; 9J.236.169; 9 J.236.172; 9 J.236.175; 9J.236.240; 9J.236.244; 9J.237.228; 9J.237.229; 9 J.237.230; 9J.237.231; 9 J.237.236; 9 J.237.237; 9 J.237.238; 9J.237.239; 9 J.237.154; 9J.237.157; 9 J.237.166; 9J.237.169; 9 J.237.172; 9 J.237.175; 9J.237.240; 9 J.237.244; 9J.238.228; 9.J.238.229; 9 J.238.230; 9 J.238.231; 9 J.238.236; 9 J.238.237; 9J.238.238; 9 J.238.239; 9 J.238.154; 9 J.238.157; 9 J.238.166; 9J.238.169; 9J.238.172; 9 J.238.175; 9 J.238.240; 9 J.238.244; 9J.239.228; 9J.239.229; 9 J.239.230; 9 J.239.231; 9J.239.236; 9J.239.237; 9J.239.238; 9J.239.239; 9J.239.154; 9 J.239.157; 9 J.239.166; 9J.239.169; 9 J.239.172; 9 J.239.175; 9 J.239.240; 9J.239.244; 9 J.154.228; 9 J.154.229; 9 J.154.230; 9 J.154.231; 9 J.154.236; 9 J.154.237; 9 J.154.238; 9J.154.239; 9J.154.154; 9J.154.157; 9 J.154.166; 9 J.154.169; 9 J.154.172; 9J.154.175; 9J.154.240; 9 J.154.244; 9J.157.228; 9 J.157.229; 9J.157.230; 9 J.157.231; 9J.157.236; 9 J.157.237; 9 J.157.238; 9 J.157.239; 9 J.157.154; 9J.157.157; 9 J.157.166; 9 J.157.169; 9 J.157.172; 9 J.157.175; 9J.157.240; 9 J.157.244; 9 J.166.228; 9J.166.229; 9J.166.230; 9 J.166.231; 9J.166.236; 9J.166.237; 9 J.166.238; 9J.166.239; 9 J.166.154; 9 J.166.157; 9J.166.166; 9 J.166.169; 9J.166.172; 9 J.166.175; 9J.166.240; 9 J.166.244; 9 J.169.228; 9 J.169.229; 9 J.169.230; 9 J.169.231; 9J.169.236; 9 J.169.237; 9 J.169.238; 9 J.169.239; 9J.169.154; 9 J.169.157; 9J.169.166; 9J.169.169; 9 J.169.172; 9 J.169.175; 9J.169.240; 9J.169.244; 9 J.172.228; 9 J.172.229; 9J.172.230; 9J.172.231; 9 J.172.236; 9 J.172.237; 9 J.172.238; 9J.172.239; 9J.172.154; 9 J.172.157; 9 J.172.166; 9 J.172.169; 9 J.172.172; 9J.172.175; 9 J.172.240; 9 J.172.244; 9 J.175.228; 9 J.175.229; 9 J.175.230; 9J.175.231; 9 J.175.236; 9 J.175.237; 9 J.175.238; 9 J.175.239; 9 J.175.154; 9 J.175.157; 9J.175.166; 9 J.175.169; 9J.175.172; 9 J.175.175; 9 J.175.240; 9 J.175.244; 9 J.240.228; 9 J.240.229; 9 J.240.230; 9.J.240.231; 9J.240.236; 9J.240.237; 9 J.240.238; 9J.240.239; 9J.240.154; 9 J.240.157; 9 J.240.166; 9 J.240.169; 9 J.240.172; 9J.240.175; 9J.240.240; 9J.240.244; 9 J.244.228; 9J.244.229; 9J.244.230; 9 J.244.231; 9 J.244.236; 9 J.244.237; 9 J.244.238; 9 J.244.239; 9 J.244.154; 9J.244.157; 9 J.244.166; 9J.244.169; 9 J.244.172; 9 J.244.175; 9J.244.240; 9J.244.244; Prodrugs of 9 X

9.L.228.228; 9.L.228.229; 9.L.228.230; 9.L.228.231; 9.L.228.236; 9.L.228.237; 9.L.228.238; 9.L.228.239; 9.L.228.154; 9.L.228.157; 9.L.228.166; 9.L.228.169; 9.L.228.172; 9.L.228.175; 9.L.228.240; 9.L.228.244; 9.L.229.228; 9.L.229.229; 9.L.229.230; 9.L.229.231; 9X.229.236; 9.L.229.237; 9.L.229.238; 9.L.229.239; 9.L.229.154; 9.L.229.157; 9.L.229.166; 9.L.229.169; 9.L.229.172; 9.L.229.175; 9.L.229.240; 9.L.229.244; 9.L.230.228; 9X.230.229; 9X.230.230; 9.L.230.231; 9.L.230.236; 9.L.230.237; 9.L.230.238; 9X.230.239; 9.L.230.154; 9.L.230.157; 9X.230.166; 9X.230.169; 9.L.23Q.172; 9X.230.175; 9.L.230.240; 9.L.230.244; 9X.231.228; 9.L.231.229; 9.L.231.230; 9.L.231.231; 9.L.231.236; 9.L.231.237; 9.L.231.238; 9X.231.239; 9X.231.154; 9.L.231.157; 9.L.231.166; 9.L.231.169; 9.L.231.172; 9X.231.175; 9.L.231.240; 9.L.231.244; 9.L.236.228; 9.L.236.229; 9.L.236.230; 9X.236.231; 9.L.236.236; 9.L.236.237; 9.L.236.238; 9.L.236.239; 9.L.236.154; 9.L.236.157; 9.L.236.166; 9.L.236.169; 9.L.236.172; 9X.236.175; 9.L.236.240; 9.L.236.244; 9X.237.228; 9X.237.229; 9X.237.230; 9X.237.231; 9X.237.236; 9X.237.237; 9X.237.238; 9X.237.239; 9X.237.154; 9X.237.157; 9X.237.166; 9X.237.169; 9X.237.172; 9X.237.175; 9X.237.240; 9X.237.244; 9X.238.228; 9X.238.229; 9X.238.230; 9X.238.231; 9X.238.236; 9X.238.237; 9X.238.238; 9X.238.239; 9X.238.154; 9X.238.157; 9X.238.166; 9X.238.169; 9X.238.172; 9X.238.175; 9X.238.240; 9X.238.244; 9X.239.228; 9X.239.229; 9X.239.230; 9X.239.231; 9X.239.236; 9X.239.237; 9X.239.238; 9X.239.239; 9X.239.154; 9X.239.157; 9X.239.166; 9X.239.169; 9X.239.172; 9X.239.175; 9X.239.240; 9X.239.244; 9X.154.228; 9X.154.229; 9X.154.230; 9X.154.231; 9X.154.236; 9X.154.237; 9X.154.238; 9X.154.239; 9X.154.154; 9X.154.157; 9X.154.166; 9X.154.169; 9X.154.172; 9X.154.175; 9X.154.240; 9X.154.244; 9X.157.228; 9X.157.229; 9X.157.230; 9X.157.231; 9X.157.236; 9X.157.237; 9X.157.238; 9X.157.239; 9X.157.154; 9X.157.157; 9X.157.166; 9X.157.169; 9X.157.172; 9X.157.175; 9.L.157.240; 9X.157.244; 9X.166.228; 9X.166.229; 9X.166.230; 9X.166.231; 9X.166.236; 9X.166.237; 9X.166.238; 9X.166.239; 9X.166.154; 9X.166.157; 9X.166.166; 9X.166.169; 9X.166.172; 9X.166.175; 9X.166.240; 9X.166.244; 9X.169.228; 9X.169.229; 9X.169.230; 9X.169.231; 9X.169.236; 9X.169.237; 9X.169.238; 9X.169.239; 9X.169.154; 9X.169.157; 9X.169.166; 9X.169.169; 9X.169.172; 9X.169.175; 9X.169.240; 9X.169.244; 9X.172.228; 9X.172.229; 9X.172.230; 9X.172.231; 9X.172.236; 9X.172.237; 9X.172.238; 9X.172.239; 9X.172.154; 9X.172.157; 9X.172.166; 9X.172.169; 9X.172.172; 9X.172.175; 9X.172.240; 9X.172.244; 9X.175.228; 9X.175.229; 9X.175.230; 9X.175.231; 9X.175.236; 9X.175.237; 9X.175.238; 9X.175.239; 9X.175.154; 9X.175.157; 9X.175.166; 9X.175.169; 9X.175.172; 9X.175.175; 9X.175.240; 9X.175.244; 9X.240.228; 9X.240.229; 9X.240.230; 9X.240.231; 9X.240.236; 9X.240.237; 9X.240.238; 9X.240.239; 9X.240.154; 9X.240.157; 9X.240.166; 9X.240.169; 9X.240.172; 9X.240.175; 9X.240.240; 9X.240.244; 9X.244.228; 9X.244.229; 9X.244.230; 9X.244.231; 9X.244.236; 9X.244.237; 9X.244.238; 9X.244.239; 9X.244.154; 9X.244.157; 9X.244.166; 9X.244.169; 9X.244.172; 9X.244.175; 9X.244.240; 9X.244.244; Prodrugs of 9.O

9.O.228.228; 9.O.228.229; 9.O.228.230; 9.O.228.231; 9.O.228.236; 9.O.228.237; 9.O.228.238; 9.0-228.239; 9.O.228.154; 9.O.228.157; 9.O.228.166; 9.O.228.169; 9.O.228.172; 9.O.228.175; 9.O.228.240; 9.O.228.244; 9.O.229.228; 9.O.229.229; 9.O.229.230; 9.O.229.231; 9.O.229.236; 9.O.229.237; 9.O.229.238; 9.O.229.239; 9.O.229.154; 9.O.229.157; 9.O.229.166; 9.Q.229.169; 9.O.229.172; 9.O.229.175; 9.O.229.240; 9.O.229.244; 9.O.230.228; 9.O.230.229; 9.O.230.23Q; 9.O.230.231; 9.O.230.236; 9.O.230.237; 9.O.230.238; 9.O.230.239; 9.O.230.154; 9.O.230.157; 9.O.230.166; 9.O.230.169; 9.O.230.172; 9.O.230.175; 9.O.230.240; 9.O.230.244; 9.Q.231.228; 9.O.231.229; 9.O.231.230; 9.O.231.231; 9.O.231.236; 9.O.231.237; 9.O.231.238; 9.O.231.239; 9.O.231.154; 9.O.231.157; 9.O.231.166; 9.O.231.169; 9.O.231.172; 9.O.231.175; 9.O.231.240; 9.O.231.244; 9.O.236.228; 9.O.236.229; 9.O.236.230; 9.O.236.231; 9.O.236.236; 9.O.236.237; 9.O.236.238; 9.O.236.239; 9.O.236.154; 9.Q.236.157; 9.O.236.166; 9.O.236.169; 9.O.236.172; 9.O.236.175; 9.O.236.240; 9.O.236.244; 9.O.237.228; 9.O.237.229; 9.O.237.230; 9.O.237.231; 9.O.237.236; 9.O.237.237; 9.O.237.238; 9.O.237.239; 9.O.237.154; 9.O.237.157; 9.O.237.166; 9.O.237.169; 9.O.237.172; 9.O.237.175; 9.O.237.240; 9.O.237.244; 9.O.238.228; 9.O.238.229; 9.O.238.230; 9.O.238.231; 9.O.238.236; 9.O.238.237; 9.O.238.238; 9.O.238.239; 9.O.238.154; 9.O.238.157; 9.O.238.166; 9.O.238.169; 9.O.238.172; 9.O.238.175; 9.O.238.240; 9.O.238.244; 9.O.239.228; 9.O.239.229; 9.O.239.230; 9.O.239.231; 9.O.239.236; 9.O.239.237; 9.O.239.238; 9.O.239.239; 9.O.239.154; 9.O.239.157; 9.O.239.166; 9.O.239.169; 9.O.239.172; 9.O.239.175; 9.O.239.240; 9.O.239.244; 9.O.154.228; 9.O.154.229; 9.O.154.230; 9.O.154.231; 9.O.154.236; 9.O.154.237; 9.O.154.238; 9.O.154.239; 9.O.154.154; 9.O.154.157; 9.O.154.166; 9.O.154.169; 9.O.154.172; 9.O.154.175; 9.O.154.240; 9.O.154.244; 9.O.157.228; 9.O.157.229; 9.O.157.23Q; 9.O.157.231; 9.O.157.236; 9.O.157.237; 9.O.157.238; 9.O.157.239; 9.O.157.154; 9.O.157.157; 9.O.157.166; 9.O.157.169; 9.O.157.172; 9.O.157.175; 9.O.157.240; 9.O.157.244; 9.O.166.228; 9.O.166.229; 9.O.166.230; 9.O.166.231; 9.O.166.236; 9.O.166.237; 9.O.166.238; 9.O.166.239; 9.O.166.154; 9.O.166.157; 9.O.166.166; 9.O.166.169; 9.O.166.172; 9.O.166.175; 9.O.166.240; 9.O.166.244; 9.O.169.228; 9.O.169.229; 9.O.169.230; 9.O.169.231; 9.O.169.236; 9.O.169.237; 9.O.169.238; 9.O.169.239; 9.O.169.154; 9.O.169.157; 9.O.169.166; 9.O.169.169; 9.O.169.172; 9.O.169.175; 9.O.169.240; 9.O.169.244; 9.O.172.228; 9.O.172.229; 9.O.172.230; 9.O172.231; 9.O.172.236; 9.O.172.237; 9.O.172.238; 9.O.172.239; 9.O.172.154; 9.O.172.157; 9.O.172.166; 9.O.172.169; 9.O.172.172; 9.O.172.175; 9.O.172.240; 9.O.172.244; 9.O.175.228; 9.O.175.229; 9.O.175.230; 9.O.175.231; 9.O.175.236; 9.O.175.237; 9.O.175.238; 9.O.175.239; 9.O.175.154; 9.O.175.157; 9.O.175.166; 9.O.175.169; 9.O.175.172; 9.O.175.175; 9.O.175.240; 9.O.175.244; 9.O.240.228; 9.O.240.229; 9.O.240.230; 9.O.240.231; 9.O.240.236; 9.O.240.237; 9.O.240.238; 9.O.240.239; 9.O.240.154; 9.O.240.157; 9.O.240.166; 9.O.240.169; 9.O.240.172; 9.O.240.175; 9.O.240.240; 9.O.240.244; 9.O.244.228; 9.O.244.229; 9.O.244.230; 9.O.244.231; 9.O.244.236; 9.O.244.237; 9.O.244.238; 9.O.244.239; 9.O.244.154; 9.O.244.157; 9.O.244.166; 9.O.244.169; 9.O.244.172; 9.O.244.175; 9.O.244.240; 9.O.244.244;

Prodrugs of 9.P 9.P.228.228; 9.P.228.229; 9.P.228.230; 9.P.228.231; 9.P.228.236; 9.P.228.237; 9.P.228.238; 9.P.228.239; 9.P.228.154; 9.P.228.157; 9.P.228.166; 9.P.228.169; 9.P.228.172; 9.P.228.175; 9.P.228.240; 9.P.228.244; 9.P.229.228; 9.P.229.229; 9.P.229.230; 9.P.229.231; 9.P.229.236; 9.P.229.237; 9.P.229.238; 9.P.229.239; 9.P.229.154; 9.P.229.157; 9.P.229.166; 9.P.229.169; 9.P.229.172; 9.P.229.175; 9.P.229.240; 9.P.229.244; 9.P.230.228; 9.P.230.229; 9.P.230.230; 9.P.230.231; 9.P.230.236; 9.P.230.237; 9.P.230.238; 9.P.230.239; 9.P.230.154; 9.P.230.157; 9.P.230.166; 9.P.230.169; 9.P.230.172; 9.P.230.175; 9.P.230.240; 9.P.230.244; 9.P.231.228; 9.P.231.229; 9.P.231.230; 9.P.231.231; 9.P.231.236; 9.P.231.237; 9.P.231.238; 9.P.231.239; 9.P.231.154; 9.P.231.157; 9.P.231.166; 9.P.231.169; 9.P.231.172; 9.P.231.175; 9.P.231.24Q; 9.P.231.244; 9.P.236.228; 9.P.236.229; 9.P.236.230; 9.P.236.231; 9.P.236.236; 9.P.236.237; 9.P.236.238; 9.P.236.239; 9.P.236.154; 9.P.236.157; 9.P.236.166; 9.P.236.169; 9.P.236.172; 9.P.236.175; 9.P.236.240; 9.P.236.244; 9.P.237.228; 9.P.237.229; 9.P.237.230; 9.P.237.231; 9.P.237.236; 9.P.237.237; 9.P.237.238; 9.P.237.239; 9.P.237.154; 9.P.237.157; 9.P.237.166; 9.P.237.169; 9.P.237.172; 9.P.237.175; 9.P.237.240; 9.P.237.244; 9.P.238.228; 9.P.238.229; 9.P.238.230; 9.P.238.231; 9.P.238.236; 9.P.238.237; 9.P.238.238; 9.P.238.239; 9.P.238.154; 9.P.238.157; 9.P.238.166; 9.P.238.169; 9.P.238.172; 9.P.238.175; 9.P.238.240; 9.P.238.244; 9.P.239.228; 9.P.239.229; 9.P.239.230; 9.P.239.231; 9.P.239.236; 9.P.239.237; 9.P.239.238; 9.P.239.239; 9.P.239.154; 9.P.239.157; 9.P.239.166; 9.P.239.169; 9.P.239.172; 9.P.239.175; 9.P.239.240; 9.P.239.244; 9.P.154.228; 9.P.154.229; 9.P.154.230; 9.P.154.231; 9.P.154.236; 9.P.154.237; 9.P.154.238; 9.P.154.239; 9.P.154.154; 9.P.154.157; 9.P.154.166; 9.P.154.169; 9.P.154.172; 9.P.154.175; 9.P.154.240; 9.P.154.244; 9.P.157.228; 9.P.157.229; 9.P.157.23Q; 9.P.157.231; 9.P.157.236; 9.P.157.237; 9.P.157.238; 9.P.157.239; 9.P.157.154; 9.P.157.157; 9.P.157.166; 9.P.157.169; 9.P.157.172; 9.P.157.175; 9.P.157.240; 9.P.157.244; 9.P.166.228; 9.P.166.229; 9.P.166.230; 9.P.166.231; 9.P.166.236; 9.P.166.237; 9.P.166.238; 9.P.166.239; 9.P.166.154; 9.P.166.157; 9.P.166.166; 9.P.166.169; 9.P.166.172; 9.P.166.175; 9.P.166.240; 9.P.166.244; 9.P.169.228; 9.P.169.229; 9.P.169.230; 9.P.169.231; 9.P.169.236; 9.P.169.237; 9.P.169.238; 9.P.169.239; 9.P.169.154; 9.P.169.157; 9.P.169.166; 9.P.169.169; 9.P.169.172; 9.P.169.175; 9.P.169.240; 9.P.169.244; 9.P.172.228; 9.P.172.229; 9.P.172.230; 9.P.172.231; 9.P.172.236; 9.P.172.237; 9.P.172.238; 9.P.172.239; 9.P.172.154; 9.P.172.157; 9.P.172.166; 9.P.172.169; 9.P.172.172; 9.P.172.175; 9.P.172.240; 9.P.172.244; 9.P.175.228; 9.P.175.229; 9.P.175.230; 9.P.175.231; 9.P.175.236; 9.P.175.237; 9.P.175.238; 9.P.175.239; 9.P.175.154; 9.P.175.157; 9.P.175.166; 9.P.175.169; 9.P.175.172; 9.P.175.175; 9.P.175.240; 9.P.175.244; 9.P.240.228; 9.P.240.229; 9.P.240.230; 9.P.240.231; 9.P.240.236; 9.P.240.237; 9.P.240.238; 9.P.240.239; 9.P.240.154; 9.P.240.157; 9.P.240.166; 9.P.24Q.169; 9.P.240.172; 9.P.240.175; 9.P.240.240; 9.P.240.244; 9.P.244.228; 9.P.244.229; 9.P.244.230; 9.P.244.231; 9.P.244.236; 9.P.244.237; 9.P.244.238; 9.P.244.239; 9.P.244.154; 9.P.244.157; 9.P.244.166; 9.P.244.169; 9.P.244.172; 9.P.244.175; 9.P.244.240; 9.P.244.244;

Prodrugs of 9.U 9.U.228.228; 9.U.228.229; 9.U.228.230; 9.U.228.231; 9.U.228.236; 9.U.228.237; 9.U.228.238; 9.U.228.239; 9.U.228.154; 9.U.228.157; 9.U.228.166; 9.U.228.169; 9.U.228.172; 9.U.228.175; 9.U.228.240; 9.U.228.244; 9.U.229.228; 9.U.229.229; 9.U.229.230; 9.U.229.231; 9.U.229.236; 9.U.229.237; 9.U.229.238; 9.U.229.239; 9.U.229.154; 9.U.229.157; 9.U.229.166; 9.U.229.169; 9.U.229.172; 9.U.229.175; 9.U.229.240; 9.U.229.244; 9.U.230.228; 9.U.230.229; 9.U.230.230; 9.U.230.231; 9.U.230.236; 9.U.230.237; 9.U.230.238; 9.U.230.239; 9.U.230.154; 9.U.230.157; 9.U.230.166; 9.U.230.169; 9.U.230.172; 9.U.230.175; 9.U.230.240; 9.U.230.244; 9.U.231.228; 9.U.231.229; 9.U.231.230; 9.U.231.231; 9.U.231.236; 9.U.231.237; 9.U.231.238; 9.U.231.239; 9.U.231.154; 9.U.231.157; 9.U.231.166; 9.U.231.169; 9.U.231.172; 9.U.231.175; 9.U.231.240; 9.U.231.244; 9.U.236.228; 9.U.236.229; 9.U.236.230; 9.U.236.231; 9.U.236.236; 9.U.236.237; 9.U.236.238; 9.U..236.239; 9.U.236.154; 9.U.236.157; 9.U.236.166; 9.U.236.169; 9.U.236.172; 9.U.236.175; 9.U.236.240; 9.U.236.244; 9.U.237.228; 9.U.237.229; 9.U.237.230; 9.U.237.231; 9.U.237.236; 9.U.237.237; 9.U.237.238; 9.U.237.239; 9.U.237.154; 9.U.237.157; 9.U.237.166; 9.U.237.169; 9.U.237.172; 9.U.237.175; 9.U.237.240; 9.U.237.244; 9.U.238.228; 9.U.238.229; 9.U.238.230; 9.U.238.231; 9.U.238.236; 9.U.238.237; 9.U.238.238; 9.U.238.239; 9.U.238.154; 9.U.238.157; 9.U.238.166; 9.U.238.169; 9.U.238.172; 9.U.238.175; 9.U.238.240; 9.U.238.244; 9.U.239.228; 9.U.239.229; 9.U.239.230; 9.U.239.231; 9.U.239.236; 9.U.239.237; 9.U.239.238; 9.U.239.239; 9.U.239.154; 9.U.239.157; 9.U.239.166; 9.U.239.169; 9.U.239.172; 9.U.239.175; 9.U.239.240; 9.U.239.244; 9.U.154.228; 9.U.154.229; 9.U.154.230; 9.U.154.231; 9.U.154.236; 9.U.154.237; 9.U.154.238; 9.U.154.239; 9.U.154.154; 9.U.154.157; 9.U.154.166; 9.U.154.169; 9.U.154.172; 9.U.154.175; 9.U.154.240; 9.U.154.244; 9.U.157.228; 9.U.157.229; 9.U.157.230; 9.U.157.231; 9.U.157.236; 9.U.157.237; 9.U.157.238; 9.U.157.239; 9.U.157.154; 9.U.157.157; 9.U.157.166; 9.U.157.169; 9.U.157.172; 9.U.157.175; 9.U.157.240; 9.U.157.244; 9.U.166.228; 9.U.166.229; 9.U.166.230; 9.U.166.231; 9.U.166.236; 9.U.166.237; 9.U.166.238; 9.U.166.239; 9.U.166.154; 9.U.166.157; 9.U.166.166; 9.U.166.169; 9.U.166.172; 9.U.166.175; 9.U.166.240; 9.U.166.244; 9.U.169.228; 9.U.169.229; 9.U.169.230; 9.U.169.231; 9.U.169.236; 9.U.169.237; 9.U.169.238; 9.U.169.239; 9.U.169.154; 9.U.169.157; 9.U.169.166; 9.U.169.169; 9.U.169.172; 9.U.169.175; 9.U.169.240; 9.U.169.244; 9.U.172.228; 9.U.172.229; 9.U.172.230; 9.U.172.231; 9.U.172.236; 9.U.172.237; 9.U.172.238; 9.U.172.239; 9.U.172.154; 9.U.172.157; 9.U.172.166; 9.U.172.169; 9.U.172.172; 9.U.172.175; 9.U.172.240; 9.U.172.244; 9.U.175.228; 9.U.175.229; 9.U.175.230; 9.U.175.231; 9.U.175.236; 9.U.175.237; 9.U.175.238; 9.U.175.239; 9.U.175.154; 9.U.175.157; 9.U.175.166; 9.U.175.169; 9.U.175.172; 9.U.175.175; 9.U.175.240; 9.U.175.244; 9.U.240.228; 9.U.240.229; 9.U.240.230; 9.U.240.231; 9.U.240.236; 9.U.240.237; 9.U.240.238; 9.U.240.239; 9.U.240.154; 9.U.240.157; 9.U.240.166; 9.U.240.169; 9.U.240.172; 9.U.240.175; 9.U.240.240; 9.U.240.244; 9.U.244.228; 9.U.244.229; 9.U.244.230; 9.U.244.231; 9.U.244.236; 9.U.244.237; 9.U.244.238; 9.U.244.239; 9.U.244.154; 9.U.244.157; 9.U.244.166; 9.U.244.169; 9.U.244.172; 9.U.244.175; 9.U.244.240; 9.U.244.244;

Prodrugs of 9.CD 9.CD.228.228; 9.CD.228.229; 9.CD.228.230; 9.CD.228.231; 9.CD.228.236; 9.CD.228.237; 9.CD.228.238; 9. CD.22% 239; 9.CD.228.154; 9.CD.228.157; 9.CD.228.166; 9.CD.228.169; 9. CD.22%.172; 9.CD.228.175; 9.CD.228.240; 9.CD.228.244; 9.CD.229.228; 9.CD.229.229; 9.CD.229.230; 9.CD.229.231; 9.CD.229.236; 9.CD.229.237; 9.CD.229.238; 9.CD.229.239; 9.CD.229.154; 9.CD.229.157; 9.CD.229.166; 9.CD.229.169; 9.CD.229.172; 9.CD.229.175; 9.CD.229.240; 9.CD.229.244; 9.CD.230.228; 9.CD.230.229; 9.CD.230.230; 9.CD.230.231; 9.CD.230.236; 9.CD.230.237; 9.CD.230.238; 9.CD.230.239; 9.CD.230.154; 9.CD.230.157; 9.CD.230.166; 9.CD.230.169; 9.CD.230.172; 9.CD.230.175; 9.CD.23Q.240; 9.CD.230.244; 9.CD.231.228; 9.CD.231.229; 9.CD.231.230; 9.CP.231.231; 9.CD.231.236; 9.CD.231.237; 9.CD.231.238; 9.CD.231.239; 9.CD.231.154; 9.CD.231.157; 9.CD.231.166; 9.CD.231.169; 9.CD.231.172; 9.CD.231.175; 9.CD.231.240; 9.CD.231.244; 9.CD.236.228; 9. CD..236.229; 9.CD.236.230; 9.CD.236.231; 9.CD.236.236; 9.CD.236.237; 9.CD.236.238; 9.CD.236.239; 9.CD.236.154; 9.CD.236.157; 9.CD.236.166; 9.CD.236.169; 9. CD.236.172; 9.CD.236.175; 9.CD.236.240; 9.CD.236.244; 9.CD.237.228; 9.CD.237.229; 9.CD.237.230; 9.CD.237.231; 9.CD.237.236; 9.CD.237.237; 9.CD.237.238; 9.CD.237.239; 9.CD.237.154; 9.CD.237.157; 9.CD.237.166; 9.CD.237.169; 9.CD.237.172; 9.CD.237.175; 9.CD.237.240; , 9.CD.237.244; 9.CD.238.228; 9.CD.238.229; 9.CD.238.230; 9.CD.238.231; 9.CD.238.236; 9.CD.238.237; 9.CD.238.238; 9.CD.238.239; 9.CD.238.154; 9.CD.238.157; 9.CD.238.166; 9.CD.238.169; 9.CD.238.172; 9.CD.238.175; 9.CD.238.240; 9.CD.238.244; 9.CD.239.228; 9.CD.239.229; 9.CD.239.230; 9.CD.239.231; 9.CD.239.236; 9.CD.239.237; 9.CD.239.238; 9.CD.239.239; 9.CD.239.154; 9.CD.239.157; 9.CD.239.166; 9.CD.239.169; 9.CD.239.172; 9.CD.239.175; 9.CD.239.240; 9.CD.239.244; 9.CD.154.228; 9.CD.154.229; 9.CD.154.230; 9.CD.154.231; 9.CD.154.236; 9.CD.154.237; 9.CD.154.238; 9.CD.154.239; 9.CD.154.154; 9.CD.154.157; 9.CD.154.166; 9.CD.154.169; 9.CD.154.172; 9.CD.154.175; 9.CD.154.240; 9.CD.154.244; 9.CD.157.228; 9.CD.157.229; 9.CD.157.230; 9.CD.157.231; 9.CD.157.236; 9.CD.157.237; 9.CD.157.238; 9.CD.157.239; 9.CD.157.154; 9.CD.157.157; 9.CD.157.166; 9.CD.157.169; 9.CD.157.172; 9.CD.157.175; 9.CD.157.240; 9.CD.157.244; 9.CD.166.228; 9.CD.166.229; 9.CD.166.230; 9.CD.166.231; 9.CD.166.236; 9.CD.166.237; 9.CD.166.238; 9.CD.166.239; 9.CD.166.154; 9.CD.166.157; 9.CD.166.166; 9.CD.166.169; 9.CD.166.172; 9.CD.166.175; 9.CD.166.240; 9.CD.166.244; 9.CD.169.228; 9.CD.169.229; 9.CD.169.230; 9.CD.169.231; 9.CD.169.236; 9.CD.169.237; 9.CD.169.238; 9.CD.169.239; 9.CD.169.154; 9.CD.169.157; 9.CD.169.166; 9.CD.169.169; 9.CD.169.172; 9.CD.169.175; 9.CD.169.240; 9.CD.169.244; 9.CD.172.228; 9.CD.172.229; 9.CD.172.230; 9.CD.172.231; 9.CD.172.236; 9.CD.172.237; 9.CD.172.238; 9.CD.172.239; 9.CD.172.154; 9.CD.172.157; 9.CD.172.166; 9.CD.172.169; 9.CD.172.172; 9.CD.172.175; 9.CD.172.240; 9.CD.172.244; 9.CD.175.228; 9.CD.175.229; 9.CD.175.230; 9.CD.175.231; 9.CD.175.236; 9.CD.175.237; 9.CD.175.238; 9.CD.175.239; 9.CD.175.154; 9.CD.175.157; 9.CD.175.166; 9.CD.175.169; 9.CD.175.172; 9.CD.175.175; 9.CD.175.240; 9.CD.175.244; 9.CD.240.228; 9.CD.240.229; 9.CD.240.230; 9.CD.240.231; 9.CD.240.236; 9.CD.240.237; 9.CD.240.238; 9.CD.240.239; 9.CD.240.154; 9.CD.240.157; 9.CD.240.166; 9.CD.240.169; 9.CD.240.172; 9.CD.240.175; 9.CD.240.240; 9.CD.240.244; 9.CD.244.228; 9.CD.244.229; 9.CD.244.230; 9.CD.244.231; 9.CD.244.236; 9.CD.244.237; 9.CD.244.238; 9.CD.244.239; 9.CD.244.154; 9.CD.244.157; 9.CD.244.166; 9.CD.244.169; 9.CD.244.172; 9.CD.244.175; 9.CD.244.240; 9.CD.244.244;

Prodrugs of 9.EB

9.EB.228.228; 9.EB.228.229; 9.EB.228.230; 9.EB.228.231; 9.EB.228.236; 9.EB.228.237; 9.EB.228.238; 9.EB.228.239; 9.EB.228.154; 9.EB.228.157; 9.EB.228.166; 9.EB.228.169; 9.EB.228.172; 9.EB.228.175; 9.EB.228.240; 9.EB.228.244; 9.EB.229.228; 9.EB.229.229; 9.EB.229.230; 9.EB.229.231; 9.EB.229.236; 9.EB.229.237; 9.EB.229.238; 9.EB.229.239; 9.EB.229.154; 9.EB.229.157; 9.EB.229.166; 9.EB.229.169; 9.EB.229.172; 9.EB.229.175; 9.EB.229.240; 9.EB.229.244; 9.EB.23Q.228; 9.EB.230.229; 9.EB.230.230; 9.EB.23Q.231; 9.EB.230.236; 9.EB.230.237; 9.EB.230.238; 9.EB.230.239; 9.EB.230.154; 9.EB.230.157; 9.EB.23Q.166; 9.EB.230.169; 9.EB.230.172; 9.EB.230.175; 9.EB.230.240; 9.EB.230.244; 9.EB.231.228; 9.EB.231.229; 9.EB.231.230; 9.EB.231.231; 9.EB.231.236; 9.EB.231.237; 9.EB.231.238; 9.EB.231.239; 9.EB.231.154; 9.EB.231.157; 9.EB.231.166; 9.EB.231.169; 9.EB.231.172; 9.EB.231.175; 9.EB.231.240; 9.EB.231.244; 9.EB.236.228; 9.EB.236.229; 9.EB.236.230; 9.EB.236.231; 9.EB.236.236; 9.EB.236.237; 9.EB.236.238; 9.EB.236.239; 9.EB.236.154; 9.EB.236.157; 9.EB.236.166; 9.EB.236.169; 9.EB.236.172; 9.EB.236.175; 9.EB.236.240; 9.EB.236.244; 9.EB.237.228; 9.EB.237.229; 9.EB.237.230; 9.EB.237.231; 9.EB.237.236; 9.EB.237.237; 9.EB.237.238; 9.EB.237.239; 9.EB.237.154; 9.EB.237.157; 9..EB.231 '.166; 9.EB.237.169; 9.EB.237.172; 9ΞB.237175; 9.EB.237.240; 9.EB.237.244; 9.EB.238.228; 9.EB.238.229; 9.EB.238.230; 9.EB.238.231; 9.EB.238.236; 9.EB.238.237; 9.EB.238.238; 9.EB.238.239; 9.EB.238.154; 9.EB.238.157; 9.EB.238.166; 9.EB.238.169; 9.EB.238.172; 9.EB.238.175; 9.EB.238.240; 9.EB.238.244; 9.EB.239.228; 9.EB.239.229; 9.EB.239.230; 9.EB.239.231; 9.EB.239.236; 9.EB.239.237; 9.EB.239.238; 9.EB.239.239; 9.EB.239.154; 9.EB.239.157; 9.EB.239.166; 9.EB.239.169; 9.EB.239.172; 9.EB.239.175; 9.EB.239.240; 9.EB.239.244; 9.EB.154.228; 9.EB.154.229; 9.EB.154.230; 9.EB.154.231; 9.EB.154.236; 9.EB.154.237; 9.EB.154.238; 9.EB.154.239; 9.EB.154.154; 9.EB.154.157; 9.EB.154.166; 9.EB.154.169; 9.EB.154.172; 9.EB.154.175; 9.EB.154.240; 9.EB.154.244; 9.EB.157.228; 9.EB.157.229; 9.EB.157.230; 9.EB.157.231; 9.EB.157.236; 9.EB.157.237; 9.EB.157.238; 9.EB.157.239; 9.EB.157.154; 9.EB.157.157; 9.EB.157.166; 9.EB.157.169; 9.EB.157.172; 9.EB.157.175; 9.EB.157.240; 9.EB.157.244; 9.EB.166.228; 9.EB.166.229; 9.EB.166.230; 9.EB.166.231; 9.EB.166.236; 9.EB.166.237; 9.EB.166.238; 9.EB.166.239; 9.EB.166.154; 9.EB.166.157; 9.EB.166.166; 9.EB.166.169; 9.EB.166.172; 9.EB.166.175; 9.EB.166.240; 9.EB.166.244; 9.EB.169.228; 9.EB.169.229; 9.EB.169.230; 9.EB.169.231; 9.EB.169.236; 9.EB.169.237; 9.EB.169.238; 9.EB.169.239; 9.EB.169.154; 9.EB.169.157; 9.EB.169.166; 9.EB.169.169; 9.EB.169.172; 9.EB.169.175; 9.EB.169.240; 9.EB.169.244; 9.EB.172.228; 9.EB.172.229; 9.EB.172.230; 9.EB.172.231; 9.EB.172.236; 9.EB.172.237; 9.EB.172.238; 9.EB.172.239; 9.EB.172.154; 9.EB.172.157; 9.EB.172.166; 9.EB.172.169; 9.EB.172.172; 9.EB.172.175; 9.EB.172.240; 9.EB.172.244; 9.EB.175.228; 9.EB.175.229; 9.EB.175.230; 9.EB.175.231; 9.EB.175.236; 9.EB.175.237; 9.EB.175.238; 9.EB.175.239; 9.EB.175.154; 9.EB.175.157; 9.EB.175.166; 9.EB.175.169; 9.EB.175.172; 9.EB.175.175; 9.EB.175.240; 9.EB.175.244; 9.EB.240.228; 9.EB.240.229; 9.EB.240.230; 9.EB.240.231; 9.EB.240.236; 9.EB.240.237; 9.EB.240.238; 9.EB.240.239; 9.EB.240.154; 9.EB.240.157; 9.EB.240.166; 9.EB.24Q.169; 9.EB.240.172; 9.EB.240.175; 9.EB.240.240; 9.EB.240.244; 9.EB.244.228; 9.EB.244.229; 9.EB.244.230; 9.EB.244.231; 9.EB.244.236; 9.EB.244.237; 9.EB.244.238; 9.EB.244.239; 9.EB.244.154; 9.EB.244.157; 9.EB.244.166; 9.EB.244.169; 9.EB.244.172; 9.EB.244.175; 9.EB.244.240; 9.EB.244.244;

Prodrugs of 10.B

10.B.228.228; 10.B.228.229; 10.B.228.230; 10.B.228.231; 1Q.B.228.236; 10.B.228.237; 10.B.228.238; 10.B.228.239; 10.B.228.154; 10.B.228.157; 10.B.228.166; 10.B.228.169; 10.B.228.172; 10.B.228.175; 1Q.B.228.240; 10.B.228.244; 10.B.229.228; 10.B.229.229; 10-B.229.230; 10.B.229.231; 10.B.229.236; 1Q.B.229.237; 10.B.229.238; 10.B.229.239; 10.B.229.154; 10.B.229.157; 10.B.229.166; 10.B.229.169; 10.B.229.172; 10.B.229.175; 10.B.229.240; 10.B.229.244; 10.B.230.228; 10.B.230.229; 10.B.230.230; 10.B.230.231; 10.B.230.236; 10.B.230.237; 10.B.230.238; 10.B.230.239; 10.B.230.154; 10.B.230.157; 10.B.230.166; 10.B.230.169; 10.B.230.172; 10.B.230.175; 10.B.230.240; 10.B.230.244; 1Q.B.231.228; 10.B.231.229; 10.B.231.230; 10.B.231.231; 10.B.231.236; 10.B.231.237; 10.B.231.238; 10.B.231.239; 10.B.231.154; 10.B.231.157; 10.B.231.166; 10.B.231.169; 10.B.231.172; 10.B.231.175; 10.B.231.240; 10.B.231.244; 10.B.236.228; 10.B.236.229; 10.B.236.230; 10.B.236.231; 10.B.236.236; 10.B.236.237; 10.B.236.238; 10.B.236.239; 10.B.236.154; 10.B.236.157; 10.B.236.166; 10.B.236.169; 10.B.236.172; 10.B.236.175; 10.B.236.240; 10.B.236.244; 10.B.237.228; 10.B.237.229; 10.B.237.230; 10.B.237.231; 10.B.237.236; 1Q.B.237.237; 1Q.B.237.238; 10.B.237.239; 10.B.237.154; 10.B.237.157; 10.B.237.166; 10.B.237.169; 10.B.237.172; 10.B.237.175; 10.B.237.240; 10.B.237.244; 10.B.238.228; 10.B.238.229; 10.B.238.230; 10.B.238.231; 10.B.238.236; 10.B.238.237; 1Q.B.238.238; 10.B.238.239; 10.B.238.154; 10.B.238.157; 10.B.238.166; 10.B.238.169; 10.B.238.172; 10.B.238.175; 10.B.238.240; 10.B.238.244; 10.B.239.228; 10.B.239.229; 10.B.239.230; IQ.B.239.231; 10.B.239.236; 10.B.239.237; 10.B.239.238; 10.B.239.239; 10.B.239.154; 10.B.239.157; 10.B.239.166; 10.B.239.169; 10.B.239.172; 10.B.239.175; 10.B.239.240; 10.B.239.244; 1Q.B.154.228; 10.B.154.229; 10.B.154.230; 10.B.154.231; 10.B.154.236; 10.B.154.237; 10.B.154.238; 10.B.154.239; 10.B.154.154; 10.B.154.157; 10.B.154.166; 10.B.154.169; 10.B.154.172; 10.B.154.175; 10.B.154.240; 10.B.154.244; 10.B.157.228; 1Q.B.157.229; 10.B.157.230; 10.B.157.231; 10.B.157.236; 10.B.157.237; 10.B.157.238; 10.B.157.239; 10.B.157.154; 10.B.157.157; 10.B.157.166; 10.B.157.169; 10.B.157.172; 10.B.157.175; 10.B.157.240; 10.B.157.244; 10.B.166.228; 10.B.166.229; 10.B.166.230; 10.B.166.231; 10.B.166.236; 10.B.166.237; 10.B.166.238; 10.B.166.239; 10.B.166.154; 10.B.166.157; 10.B.166.166; 10.B.166.169; 10.B.166.172; 10.B.166.175; 10.B.166.240; 10.B.166.244; 10.B.169.228; 10.B.169.229; 10.B.169.230; 10.B.169.231; 10.B.169.236; 10.B.169.237; 10.B.169.238; 10.B.169.239; 10.B.169.154; 10.B.169.157; 10.B.169.166; 10.B.169.169; 10.B.169.172; 10.B.169.175; 10.B.169.240; 10.B.169.244; 10.B.172.228; 10.B.172.229; 1Q.B.172.230; 10.B.172.231; 10.B.172.236; 10.B.172.237; 10.B.172.238; 10.B.172.239; 10.B.172.154; 10.B.172.157; 10.B.172.166; 10.B.172.169; 10.B.172.172; 10.B.172.175; 10.B.172.240; 10.B.172.244; 10.B.175.228; 10.B.175.229; 10.B.175.230; 10.B.175.231; 10.B.175.236; 10.B.175.237; 10.B.175.238; 10.B.175.239; 10.B.175.154; 10.B.175.157; 10.B.175.166; 10.B.175.169; 10.B.175.172; 10.B.175.175; 10.B.175.240; 10.B.175.244; 10.B.240.228; 10.B.240.229; 10.B.240.230; 10.B.240.231; 10.B.240.236; 10.B.240.237; 10.B.240.238; 10.B.240.239; 10.B.240.154; 10.B.240.157; 10.B.240.166; 10.B.240.169; 10.B.240.172; 10.B.240.175; 10.B.240.240; 10.B.240.244; 10.B.244.228; 10.B.244.229; 10.B.244.230; 10.B.244.231; 10.B.244.236; 10.B.244.237; 10.B.244.238; 10.B.244.239; 10.B.244.154; 10.B.244.157; 10.B.244.166; 10.B.244.169; 10.B.244.172; 10.B.244.175; 1Q.B.244.240; 10.B.244.244;

Prodrugs of 10.D

10.P.228.228; 10.D.228.229; 10.D.228.230; 1Q.P.228.231; 10.D.228.236; 10.D.228.237; 10.D.228.238; 1Q.P.228.239; 10.D.228.154; 10.D.228.157; 10.D.228.166; 10.D.228.169; 10.P.228.172; 10.D.228.175; 10.D.228.240; 10.D.228.244; 10.D.229.228; 10.D.229.229; 10.D.229.230; 10.D.229.231; 10.D.229.236; 10.D.229.237; 10.D.229.238; 10.D.229.239; 10.D.229.154; 10.D.229.157; 10.D.229.166; 10.D.229.169; 10.D.229.172; 10.D.229.175; 10.D.229.240; 10.D.229.244; 10.P.23Q.228; 1Q.P.230.229; 10.D.230.230; 10.D.230.231; 10.D.230.236; 10.D.230.237; 10.D.230.238; 10.D.230.239; 10.D.230.154; 10.D.230.157; 1Q.P.230.166; 10.D.230.169; 10.D.230.172; IO.D.230.175; 10.D.230.240; 10.D.230.244; IO.D.231.228; 10.D.231.229; 10.D.231.230; 10.D.231.231; 10.D.231.236; 10.D.231.237; 10.D.231.238; 10.D.231.239; 10.D.231.154; 10.D.231.157; 10.D.231.166; 10.D.231.169; 10.D.231.172; 10.D.231.175; 10.D.231.240; 10.D.231.244; 1Q.P.236.228; 10.D.236.229; 10.D.236.230; 10.D.236.231; 10.D.236.236; 10.D.236.237; . 10.D.236.238; 10.D.236.239; 10.D.236.154; 10.D.236.157; 10.D.236.166; 10.D.236.169; 10.D.236.172; 10.D.236.175; IO.D.236.240; 10.D.236.244; 10.D.237.228; 10.D.237.229; 10.D.237.230; 10.D.237.231; 10.D.237.236; 10.D.237.237; 10.D.237.238; 10.D.237.239; 10.D.237.154; 10.D.237.157; 10.D.237.166; 10.D.237.169; 10.D.237.172; IO.D.237.175; 10.P.237.240; 10.P.237.244; 10.P.238.228; IO.P.238.229; 10.P.238.230; 10.P.238.231; 10.P.238.236; 10.P.238.237; 10.P.238.238; 10.P.238.239; 10.P.238.154; 10.P.238.157; 10.D.238.166; 10.P.238.169; 10.P.238.172; 10.P.238.175; 10.P.238.240; 10.D.238.244; 10.P.239.228; 10.P.239.229; 10.P.239.230; 10.P.239.231; 10.D.239.236; 1Q.P.239.237; 10.P.239.238; 10.P.239.239; 10.P.239.154; 10.D.239.157; 10.P.239.166; IO.P.239.169; 1Q.P.239.172; 10.P.239.175; 10.P.239.240; 10.P.239.244; 10.P.154.228; 10.P.154.229; 10.P.154.230; 10.P.154.231; 10.P.154.236; 10.P.154.237; 10.P.154.238; 10.P.154.239; 10.P.154.154; 10.P.154.157; 10.P.154.166; 10.P.154.169; 10.P.154.172; 10.P.154.175; 10.P.154.240; 10.P.154.244; 10.P.157.228; 10.P.157.229; 10.P.157.230; 10.P.157.231; 10.P.157.236; 10.P.157.237; 10.P.157.238; 10.P.157.239; 10.P.157.154; 10.0.157.157; 10.P.157.166; 10.P.157.169; 10.P.157.172; 10.P.157.175; 10.P.157.240; 10.P.157.244; 10.P.166.228; 10.P.166.229; 10.P.166.230; 10.P.166.231; 10.P.166.236; 10.P.166.237; 10.P.166.238; 10.P.166.239; 10.P.166.154; 10.P.166.157; 10.P.166.166; 10.P.166.169; 10.P.166.172; 10.P.166.175; 10.P.166.240; 10.P.166.244; 10.D.169.228; 10.P.169.229; 10.P.169.230; 10.P.169.231; 10.P.169.236; 10.P.169.237; 10.P.169.238; 10.P.169.239; 10.P.169.154; 10.P.169.157; 10.P.169.166; 10.P.169.169; 10.P.169.172; 10.P.169.175; 10.P.169.240; 10.D.169.244; 10.P.172.228; 10.P.172.229; 10.P.172.230; 10.P.172.231; 10.P.172.236; 10.P.172.237; 10.P.172.238; 10.P.172.239; 10.D.172.154; 10.D.172.157; 10.D.172.166; 10.D.172.169; 10.D.172.172; 10.D.172.175; 10.D.172.240; 10.D.172.244; 10.D.175.228; 10.D.175.229; 10.D.175.230; 10.D.175.231; 10.D.175.236; 10.D.175.237; 10.D.175.238; 10.D.175.239; 10.D.175.154; 10.D.175.157; 10.D.175.166; 10.D.175.169; 10.D.175.172; 10.D.175.175; 10.D.175.240; 10.D.175.244; 10.D.240.228; 10.D.240.229; 10.D.240.230; 1Q.D.240.231; 10.D.240.236; 10.D.240.237; 10.D.240.238; 10.D.240.239; 10.D.240.154; 10.D.240.157; 10.D.240.166; 10.D.240.169; 10.D.240.172; 10.D.240.175; 10.D.240.240; 10.D.240.244; 10.D.244.228; 10.D.244.229; 10.D.244.23Q; 10.D.244.231; 10.D.244.236; 10.D.244.237; 10.D.244.238; 10.D.244.239; 10.D.244.154; 10.D.244.157; 10.D.244.166; 10.D.244.169; 10.D.244.172; 10.D.244.175; 10.D.244.240; 10.D.244.244;

Prodrugs of 10.AB

10.AB.228.228; 10.AB.228.229; 10.AB.228.230; 10.AB.228.231; 10.AB.228.236; 10.AB.228.237; 10AB.228.238; 10.AB.228.239; 10.AB.228.154; 10.AB.228.157; 10.AB.228.166; 10AB.228.169; 1Q.AB.228.172; 10.AB.228.175; 10.AB.228.240; 10.AB.228.244; 10.AB.229.228; 10.AB.229.229; 10.AB.229.230; 10.AB.229.231; 10.AB.229.236; 10.AB.229.237; 10.AB.229.238; 1Q.AB.229.239; 10.AB.229.154; 10.AB.229.157; 10AB.229.166; 10. AB.229.169; 10.AB.229.172; 10.AB.229.175; 10.AB.229.240; 10.AB.229.244; 10.AB.230.228; 1Q.AB.230.229; 10.AB.230.230; 10.AB.230.231; 10.AB.230.236; 10.AB.230.237; 10.AB.230.238; 10.AB.230.239; 10.AB.230.154; 10.AB.230.157; 10.AB.230.166; 10.AB.230.169; 10.AB.230.172; 10.AB.230.175; 10.AB.230.240; 10.AB.230.244; 10.AB.231.228; 10.AB.231.229; 10.AB.231.230; 10.AB.231.231; 10.AB.231.236; 10.AB.231.237; 10.AB.231.238; 10.AB.231.239; 10.AB.231.154; 10.AB.231.157; 10.AB.231.166; 10.AB.231.169; 10.AB.231.172; 10.AB.231.175; 10.AB.231.240; 10.AB.231.244; 10.AB.236.228; 10.AB.236.229; 10.AB.236.230; 10.AB.236.231; 10.AB.236.236; 10.AB.236.237; 10.AB.236.238; IO.AB.236.239; 10.AB.236.154; 10.AB.236.157; 10.AB.236.166; 10.AB.236.169; 10.AB.236.172; 10.AB.236.175; 10.AB.236.240; 10.AB.236.244; 10.AB.237.228; 10.AB.237.229; 10.AB.237.230; 10.AB.237.231; 10.AB.237.236; 10.AB.237.237; 10.AB.237.238; 10.AB.237.239; 10.AB.237.154; 10.AB.237.157; 10.AB.237.166; 10.AB.237.169; 1Q.AB.237.172; 10.AB.237.175; 10.AB.237.240; 10.AB.237.244; 10.AB.238.228; 10.AB.238.229; 10.AB.238.230; 10.AB.238.231; 10.AB.238.236; 10.AB.238.237; 10.AB.238.238; 10. AB.238.239; 10.AB.238.154; 10.AB.238.157; 10.AB.238.166; 10.AB.238.169; 10.AB.238.172; 10. AB.238.175; 10.AB.238.240; 10.AB.238.244; 10.AB.239.228; 10.AB.239.229; 10.AB.239.230; 10.AB.239.231; 10.AB.239.236; 10.AB.239.237; 10.AB.239.238; 10.AB.239.239; 10.AB.239.154; 10.AB.239.157; 10.AB.239.166; 10.AB.239.169; 10. AB.239.172; 10.AB.239.175; 10. AB.239.240; 10.AB.239.244; 10.AB.154.228; 10.AB.154.229; 10.AB.154.230; 10.AB.154.231; IO-AB.154.236; 10.AB.154.237; 10.AB.154.238; 10.AB.154.239; 10.AB.154.154; 10.AB.154.157; 10.AB.154.166; 10.AB.154.169; 10.AB.154.172; 10.AB.154.175; 10.AB.154.240; 10.AB.154.244; 10.AB.157.228; 10.AB.157.229; 10.AB.157.230; 10.AB.157.231; 10.AB.157.236; 10.AB.157.237; 10.AB.157.238; 10.AB.157.239; 10.AB.157.154; 10.AB.157.157; 10.AB.157.166; 10.AB.157.169; IO.AB.157.172; 10.AB.157.175; 10.AB.157.240; 10.AB.157.244; 10.AB.166.228; 10. AB.166.229; 10.AB.166.230; 10.AB.166.231; 10.AB.166.236; 10.AB.166.237; 10.AB.166.238; 10.AB.166.239; 10.AB.166.154; 10.AB.166.157; 10.AB.166.166; 10.AB.166.169; 10.AB.166.172; 10.AB.166.175; 10.AB.166.240; 10.AB.166.244; 10.AB.169.228; 10.AB.169.229; IO.AB.169.230; 10.AB.169.231; 10.AB.169.236; 10.AB.169.237; 10.AB.169.238; 10.AB.169.239; 10.AB.169.154; 10.AB.169.157; 10.AB.169.166; 10.AB.169.169; 10.AB.169.172; 10.AB.169.175; 10.AB.169.240; 10.AB.169.244; 10.AB.172.228; 10.AB.172.229; 10.AB.172.230; 10.AB.172.231; 10.AB.172.236; 10.AB.172.237; 10.AB.172.238; 10.AB.172.239; 10.AB.172.154; 10.AB.172.157; 10.AB.172.166; 10.AB.172.169; 10.AB.172.172; 10.AB.172.175; 1Q.AB.172.240; 10.AB.172.244; 10. AB.175.228; 10.AB.175.229; 10.AB.175.230; 10.AB.175.231; 1Q.AB.175.236; 10.AB.175.237; 10.AB.175.238; 10.AB.175.239; 10.AB.175.154; 10.AB.175.157; 10.AB.175.166; 10.AB.175.169; 10.AB.175.172; 10.AB.175.175; 1Q.AB.175.240; 10.AB.175.244; 10.AB.240.228; 10.AB.240.229; 10.AB.240.230; 10.AB.240.231; 10.AB.240.236; 10.AB.240.237; 10.AB.240.238; 10.AB.240.239; 10.AB.240.154; 10.AB.240.157; 10.AB.240.166; 10.AB.240.169; 10.AB.240.172; 10.AB.240.175; 10.AB.240.240; 10.AB.240.244; 10.AB.244.228; 10.AB.244.229; 10.AB.244.230; 10.AB.244.231; 10.AB.244.236; 10.AB.244.237; 10.AB.244.238; 10.AB.244.239; 10.AB.244.154; 10.AB.244.157; 10.AB.244.166; 10.AB.244.169; 10.AB.244.172; 10.AB.244.175; 10.AB.244.240; 10.AB.244.244;

Prodrugs of 10.BI

10.BI.228.228; 10.BI.228.229; 10.BI.228.230; 1Q.BI.228.231; 10.BI.228.236; 10.BI.228.237; 10.BI.228.238; 10.BI.228.239; 10.BI.228.154; 10.BI.228.157; 10.BI.228.166; 10.BI.228.169; 10.BI.228.172; 10.BI.228.175; 10.BI.228.240; 10.BI.228.244; 10.BI.229.228; 10.BI.229.229; 10.BI.229.230; 10.BI.229.231; 10.BI.229.236; 10.BI.229.237; 10.BI.229.238; 10.BI.229.239; 10.BI.229.154; 10.BI.229.157; 10.BI.229.166; 10.BI.229.169; 10.BI.229.172; 10.BI.229.175; 10.BI.229.240; 10.BI.229.244; 10.BI.230.228; 10.BI.230.229; 10.BI.230.230; 10.BI.230.231; 10.BI.230.236; 10.BI.230.237; 10.BI.230.238; 10.BI.230.239; 10.BI.230.154; 10.BI.230.157; 10.BI.230.166; 10.BI.230.169; 10.BI.230.172; 10.BI.230.175; 10.BI.230.240; 10.BI.230.244; 10.BI.231.228; 10.BI.231.229; 10.BI.231.230; 10.BL231.231; 10.BI.231.236; 10.BI.231.237; 10.BI.231.238; 10.BI.231.239; 10.BI.231.154; 10.BI.231.157; 10.BI.231.166; 10.BI.231.169; 10.BI.231.172; 10.BI.231.175; 10.BI.231.240; 10.BI.231.244; 10.BI.236.228; 10.BI.236.229; 10.BI.236.230; 10.BI.236.231; 10.BI.236.236; 10.BI.236.237; 10.BI.236.238; 10.BI.236.239; 10.BI.236.154; 10.BI.236.157; 10.BI.236.166; 10.BI.236.169; 10.BI.236.172; 10.BI.236.175; 10.BI.236.240; 10.BI.236.244; 10.BI.237.228; 10.BI.237.229; 10.BI.237.230; 10.BI.237.231; 10.BI.237.236; 10.BI.237.237; 10.BI.237.238; 10.BI.237.239; 10.BI.237.154; 10.BI.237.157; 10.BL237.166; 10.BI.237.169; 10.BI.237.172; 10.BL237.175; 10.BI.237.240; 10.BI.237.244; 10.BI.238.228; 10.BI.238.229; 10.BI.238.230; 10.BI.238.231; 10.BI.238.236; 10.BI.238.237; 10.BI.238.238; 10.BI.238.239; 10.BI.238.154; 10.BI.238.157; 10.BI.238.166; 10.BI.238.169; 10.BI.238.172; 10.BL238.175; 10.BI.238.240; 10.BI.238.244; 10.BI.239.228; 10.BI.239.229; 10.BI.239.230; 10.BI.239.231; 10.BI.239.236; 10.BI.239.237; 10.BI.239.238; 10.BI.239.239; 10.BI.239.154; 10.BI.239.157; 1Q.BL239.166; 10.BI.239.169; 10.BI.239.172; 10.BI.239.175; 10.BI.239.240; 10.BI.239.244; 10.BI.154.228; 10.BI.154.229; 10.BI.154.230; 10.BI.154.231; IO.BI.154.236; IO.BI.154.237; 10.BI.154.238; 10.BI.154.239; 10.BI.154.154; 10.BI.154.157; 10.BI.154.166; 10.BI.154.169; 10.BI.154.172; 10.BI.154.175; 1Q.BI.154.240; 10.BI.154.244; IO.BI.157.228; 10.BI.157.229; 10.BI.157.230; 10.BI.157.231; 10.BI.157.236; 10.BL157.237; 10.BI.157.238; 10.BI.157.239; 10.BI.157.154; 1031.157.157; 10.BI.157.166; 10.BI.157.169; IO.BI.157.172; 10.BI.157.175; 10.BI.157.240; 10.BI.157.244; 10.BI.166.228; 10.BI.166.229; 10.BI.166.230; 10.BI.166.231; 10.BI.166.236; 10.BI.166.237; 10.BI.166.238; 10.BI.166.239; 10.BI.166.154; 10.BI.166.157; 10.BI.166.166; 1Q.BI.166.169; 10.BI.166.172; 10.BI.166.175; 10.BI.166.240; 10.BI.166.244; 10.BI.169.228; 10.BI.169.229; 10.BI.169.230; 10.BI.169.231; 10.BI.169.236; 10.BI.169.237; 10.BI.169.238; 10.BI.169.239; 10.BI.169.154; 10.BI.169.157; 10.BI.169.166; 10.BI.169.169; 10.BI.169.172; 10.BL169.175; 10.BI.169.240; IO.BI.169.244; IO.BI.172.228; 10.BI.172.229; 10.BI.172.230; 10.BI.172.231; IO.BI.172.236; 10.BI.172.237; IO.BI.172.238; 10.BI.172.239; 10.BI.172.154; 10.BI.172.157; IO.BI.172.166; 10.BI.172.169; 10.BI.172.172; 10.BI.172.175; 10.BI.172.240; 10.BI.172.244; 10.BI.175.228; 10.BI.175.229; IO.BI.175.230; 10.BI.175.231; 10.BI.175.236; 10.BI.175.237; 10.BI.175.238; 10.BI.175.239; 10.BI.175.154; 10.BI.175.157; 10.BI.175.166; 10.BI.175.169; 10.BI.175.172; 10.BI.175.175; 10.BI.175.240; 10.BI.175.244; 10.BI.240.228; 10.BI.240.229; 10.BI.240.230; 10.BI.240.231; 10.BI.240.236; 10.BI.240.237; 10.BI.240.238; 10.BI.240.239; 10.BI.240.154; 10.BI.240.157; 10.BI.240.166; 10.BI.240.169; 10.BI.240.172; 10.BI.240.175; 10.BI.240.240; 10.BI.240.244; 10.BI.244.228; 10.BI.244.229; 10.BI.244.230; 10.BI.244.231; 10.BI.244.236; 10.BI.244.237; 10.BI.244.238; 10.BI.244.239; 10.BL244.154; 10.BI.244.157; 10.BI.244.166; 10.BI.244.169; 10.BI.244.172; 10.BI.244.175; 10.BI.244.240; 10.BI.244.244;

Prodrugs of 10.1

10.1.228.228; 10.1.228.229; 10.1.228.230; 10.1.228.231; 10.1.228.236; 10.1.228.237; 10.1.228.238; 10.1.228.239; 10.1.228.154; 10.1.228.157; 10.1.228.166; 10.1.228.169; 10.1.228.172; 10.1.228.175; 10.1.228.240; 10.1.228.244; 10.1.229.228; 10.1.229.229; 10.1.229.230; 10.1.229.231; 10.1.229.236; 10.1.229.237; 10.1.229.238; 10.1.229.239; 10.1.229.154; 10.1.229.157; 10.1.229.166; 10.1.229.169; 10.1.229.172; 10.1.229.175; 10.1.229.240; 10.1.229.244; 10.1.230.228; 10.1.230.229; 10.1.230.230; 10.1.230.231; 10.1.230.236; 10.1.230.237; 10.1.230.238; 10.1.230.239; 10.1.230.154; 10.1.230.157; 10.1.230.166; 10.1.230.169; 10.1.230.172; 10.1.230.175; 10X230.240; 10.1.230.244; 10.1.231.228; 10.1.231.229; 10.1.231.230; 10.1.231.231; 10.1.231.236; 10.1.231.237; 10.1.231.238; 10.1.231.239; 10.1.231.154; 10.1.231.157; 10.1.231.166; 10.1.231.169; 10.1.231.172; 10.1.231.175; 10.1.231.240; 10.1.231.244; 10.1.236.228; 10.1.236.229; 10.1.236.230; 10.1.236.231; 10.1.236.236; 10.1.236.237; 10.1.236.238; 10.1.236.239; 10.1.236.154; 10.1.236.157; 10.1.236.166; 10.1.236.169; 10.1.236.172; 10.1.236.175; 10.1.236.240; 10.1.236.244; 10.1.237.228; 10.1.237.229; 10.1.237.230; 10.1.237.231; 10.1.237.236; 10.1.237.237; 10.1.237.238; 10.1.237.239; 10.1.237.154; 10.1.237.157; 10.1.237.166; 10.1.237.169; 10.1.237.172; 10.1.237.175; 10.1.237.240; 10.1.237.244; 10.1.238.228; 10.1.238.229; 10.1.238.230; 10.1.238.231; 10.1.238.236; 10.1.238.237; 10.1.238.238; 10.1.238.239; 10.1.238.154; 10.1.238.157; 10.1.238.166; 10.1.238.169; 10.1.238.172; 10.1.238.175; 10.1.238.240; 10.1.238.244; 10.1.239.228; 10.1.239.229; 10.1.239.230; 10.1.239.231; 10.1.239.236; 10.1.239.237; 10.1.239.238; 10.1.239.239; 10.1.239.154; 10.1.239.157; 10.1.239.166; 10.1.239.169; 10.1.239.172; 10.1.239.175; 10.1.239.240; 10.1.239.244; 10.1.154.228; 10.1.154.229; 10.1.154.230; 10.1.154.231; 10.1.154.236; 10.1.154.237; 10.1.154.238; 10-1.154.239; 10.1.154.154; 10.1.154.157; 10.1.154.166; 10.1.154.169; 10.1.154.172; 10.1.154.175; 10.1.154.240; 10.1.154.244; 10.1.157.228; 10.1.157.229; 10.1.157.230; 10.1.157.231; 10.1.157.236; 10.1.157.237; 10.1.157.238; 10.1.157.239; 101.157.154; 10.1.157.157; 10.1.157.166; 10.1.157.169; 10.1.157.172; 10.1.157.175; 10.1.157.240; 10.1.157.244; 10.1.166.228; 10.1.166.229; 10.1.166.230; 10.1.166.231; 10.1.166.236; 10.1.166.237; 10.1.166.238; 10.1.166.239; 10.1.166.154; 10.1.166.157; 10.1.166.166; 10.1.166.169; 10.1.166.172; 10.1.166.175; 10.1.166.240; 10.1.166.244; 10.1.169.228; 1Q.I.169.229; 101.169.230; 10.1.169.231; 10.1.169.236; 10.1.169.237; 10.1.169.238; 10.1.169.239; 10.1.169.154; 10.1.169.157; 10.1.169.166; 10.1.169.169; 10.1.169.172; 10.1.169.175; 10.1.169.240; 10.1.169.244; 10.1.172.228; 10.1.172.229; 10.1.172.230; 10.1.172.231; 10.1.172.236; 10.1.172.237; 10.1.172.238; 10.1.172.239; 10.1.172.154; 10.1.172.157; 10.1.172.166; 10.1.172.169; 10.1.172.172; 10.1.172.175; 10.1.172.240; 10.1.172.244; 10.1.175.228; 10.1.175.229; 10.1.175.230; 10.1.175.231; 10.1.175.236; 10.1.175.237; 10.1.175.238; 10.1.175.239; 10.1.175.154; 10.1.175.157; 10.1.175.166; 10.1.175.169; 10.1.175.172; 10.1.175.175; 10.1.175.240; 10.1.175.244; 10.1.240.228; 10.1.240.229; 10.1.240.230; 10.1.240.231; 10.1.240.236; 10.1.240.237; 10.1.240.238; 10.1.240.239; 10.1.240.154; 10.1.240.157; 10.L240.166; 10.1.240.169; 10-1.240.172; 10.1.240.175; 10.1.240.240; 10.1.240.244; 10.1.244.228; 10.1.244.229; 10.1.244.230; 10.1.244.231; 10.1.244.236; 10.1.244.237; 10.1.244.238; 10.1.244.239; 10.1.244.154; 10.1.244.157; 10.1.244.166; 10.1.244.169; 10.1.244.172; 10.1.244.175; 10.1.244.240; 10.1.244.244;

Prodrugs of 10. T

10.J.228.228; 10.J.228.229; 10.J.228.230; 10.J.228.231; 10.J.228.236; 10.J.228.237; 10.J.228.238; 10.J.228.239; 10.J.228.154; 10J.228.157; 10.J.228.166; IO.J.228.169; IO.J.228.172; 10.J.228.175; 10.J.228.240; 10.J.228.244; IO.J.229.228; IOJ.229.229; 10.J.229.230; 10.J.229.231; IO.J.229.236; 10.J.229.237; IO.J.229.238; IO.J.229.239; 10.J.229.154; 10.J.229.157; IO.J.229.166; IO.J.229.169; 10.J.229.172; 1O.].229.175; 10.J.229.240; 10.J.229.244; 10.J.230.228; IOJ.230.229; 1QJ.230.230; 10.J.230.231; IO.J.230.236; IOJ.230.237; 10.J.230.238; 10.J.230.239; 10.J.230.154; 10.J.230.157; 10.J.230.166; 10.J.230.169; 10.J.230.172; 10.J.230.175; 10.J.230.240; 10.J.230.244; 10.J.231.228; 10.J.231.229; IO.J.231.230; IOJ.231.231; 10.J.231.236; IO.J.231.237; IO.J.231.238; 10.J.231.239; 10.J.231.154; IO.J.231.157; 10.J.231.166; 10.J.231.169; 10.J.231.172; 10.J.231.175; 10.J.231.240; IO.J.231.244; IOJ.236.228; 10.J.236.229; 10.J.236.230; IO.J.236.231; IO.J.236.236; 10J.236.237; IOJ.236.238; IO.J.236.239; IO.J.236.154; 10.J.236.157; IOJ.236.166; IO.J.236.169; 10.J.236.172; IO.J.236.175; 10.J.236.240; IO.J.236.244; 10.J.237.228; 10.J.237.229; 10.J.237.230; IO.J.237.231; IO.J.237.236; 10.J.237.237; IO.J.237.238; 10.J.237.239; 10.J.237.154; IO.J.237.157; 10.J.237.166; IO.J.237.169; 10.J.237.172; IO.J.237.175; 10.J.237.240; 10.J.237.244; 10.J.238.228; 10.J.238.229; IO.J.238.230; IO.J.238.231; 10.J.238.236; 10.J.238.237; IOJ.238.238; 10.J.238.239; 10.J.238.154; IOJ.238.157; IOJ.238.166; 10.J.238.169; IO.J.238.172; 1Q.J.238.175; 10.J.238.240; IOJ.238.244; 10.J.239.228; 10.J.239.229; 10.J.239.230; IOJ.239.231; 10.J.239.236; IOJ.239.237; IO.J.239.238; 10.J.239.239; 10.J.239.154; IO.J.239.157; 10.J.239.166; 10.J.239.169; IO.J.239.172; 10.J.239.175; 10.J.239.240; 10.J.239.244; 10.J.154.228; 10.J.154.229; IO.J.154.230; 10.J.154.231; IO.J.154.236; 10.J.154.237; IOJ.154.238; IO.J.154.239; IOJ.154.154; 10.J.154.157; IOJ.154.166; 10.J.154.169; IOJ.154.172; IO.J.154.175; 10.J.154.240; 10.J.154.244; 10.J.157.228; IO.J.157.229; IO.J.157.230; IO.J.157.231; 10.J.157.236; 1Q.J.157.237; 10.J.157.238; IOJ.157.239; 10.J.157.154; IO.J.157.157; IO.J.157.166; IO.J.157.169; 10.J.157.172; 10.J.157.175; 10.J.157.240; 10.J.157.244; 10.J.166.228; IOJ.166.229; 10.J.166.230; 10.J.166.231; 10.J.166.236; IOJ.166.237; 10J.166.238; 10.J.166.239; IO.J.166.154; IO.J.166.157; 10.J.166.166; 10.J.166.169; IOJ.166.172; 10.J.166.175; 10.J.166.240; IO.J.166.244; 10.J.169.228; 10.J.169.229; 10.J.169.230; IO.J.169.231; 10.J.169.236; 10.J.169.237; 10J.169.238; IOJ.169.239; IOJ.169.154; IOJ.169.157; 10.J.169.166; 10.J.169.169; IOJ.169.172; IO.J.169.175; 10.J.169.240; IO.J.169.244; IO.J.172.228; IO.J.172.229; IO.J.172.230; IO.J.172.231; IOJ.172.236; IO.J.172.237; 10.J.172.238; 10.J.172.239; IO.J.172.154; 10.].172.157; IOJ.172.166; 10.J.172.169; IO.J.172.172; 10.J.172.175; IOJ.172.240; IOJ.172.244; 10.J.175.228; IOJ.175.229; 10.J.175.230; IQJ.175.231; 10.J.175.236; IO.J.175.237; 10.J.175.238; 1Q.J.175.239; 10.J.175.154; 10.J.175.157; 10J.175.166; IOJ.175.169; IOJ.175.172; 10.J.175.175; 10.J.175.240; 10.J.175.244; 10.J.240.228; IO.J.240.229; IO.J.240.230; 10.J.240.231; 10.J.240.236; 10.J.24Q.237; IOJ.240.238; 10.J.240.239; IO.J.240.154; 10.J.240.157; 10.J.240.166; 10.J.240.169; 10.J.240.172; IOJ.240.175; IO.J.240.240; IO.J.240.244; 10.J.244.228; IO.J.244.229; 10.J.244.230; IO.J.244.231; 10.J.244.236; 10.J.244.237; 10.J.244.238; 10.J.244.239; 10.J.244.154; IQJ.244.157; 10.J.244.166; 10.J.244.169; IO.J.244.172; 10.J.244.175; 10.J.244.240; IOJ.244.244;

Prodrugs of 10.L

IO.L.228.228; 1Q.L.228.229; 10.L.228.230; 10.L.228.231; 10.L.228.236; 10.L.228.237; 10.L.228.238; 10.L.228.239; 10.L.228.154; 10.L.228.157; 10.L.228.166; 10.L.228.169; 10.L.228.172; 10.L.228.175; 10.L.228.240; 10.L.228.244; 10.L.229.228; 10.L.229.229; 10.L.229.230; 10.L.229.231; 10.L.229.236; 10.L.229.237; 10.L.229.238; 10.L.229.239; 10.L.229.154; 10.L.229.157; 10.L.229.166; 10.L.229.169; 10.L.229.172; 10.L.229.175; 10.L.229.240; 10.L.229.244; 10.L.23Q.228; 10.L.230.229; 10.L.230.230; 10.L.230.231; 10.L.230.236; 10.L.230.237; 10.L.230.238; 10.L.230.239; 10.L.230.154; 10.L.230.157; 10.L.230.166; 10.L.230.169; 10.L.23Q.172; 10.L.230.175; 10.L.230.240; 10.L.230.244; 10.L.231.228; 10.L.231.229; 10.L.231.230; 10.L.231.231; 10.L.231.236; 10.L.231.237; 10.L.231.238; 10.L.231.239; 10.L.231.154; 10.L.231.157; 10.L.231.166; 10.L.231.169; 10.L.231.172; 10.L.231.175; 10.L.231.240; 10.L.231.244; 10.L.236.228; 10.L.236.229; 10.L.236.230; 10.L.236.231; 10.L.236.236; 10.L.236.237; 10.L.236.238; 10.L.236.239; 10.L.236.154; 10.L.236.157; 10.L.236.166; 10.L.236.169; 10.L.236.172; 10.L.236.175; 1Q.L.236.240; 10.L.236.244; 10.L.237.228; 10.L.237.229; 10.L.237.230; 10.L.237.231; 10.L.237.236; 10.L.237.237; 10.L.237.238; 10.L.237.239; 10.L.237.154; 10.L.237.157; 10.L.237.166; 10.L.237.169; 10.L.237.172; 10.L.237.175; 10.L.237.240; 10.L.237.244; 10.L.238.228; 10.L.238.229; 10.L.238.230; 10.L.238.231; 10.L.238.236; 10.L.238.237; 10.L.238.238; 10.L.238.239; 10.L.238.154; 10.L.238.157; 10.L.238.166; 10.L.238.169; 10.L.238.172; 10.L.238.175; 10.L.238.240; 10.L.238.244; 10.L.239.228; 10.L.239.229; 10.L.239.230; IO.L.239.231; 10.L.239.236; 10.L.239.237; 1QX.239.238; 10.L.239.239; 10.L.239.154; 10X.239.157; 1QX.239.166; 10.L.239.169; 10.L.239.172; 10.L.239.175; 1QX.239.240; 10.L.239.244; 10.L.154.228; 10.L.154.229; 10.L.154.230; 10.L.154.231; 10.L.154.236; 10.L.154.237; 10.L.154.238; 10.L.154.239; 10.L.154.154; 10.L.154.157; 10.L.154.166; 10.L.154.169; 10.L.154.172; 10.L.154.175; 10.L.154.240; 10.L.154.244; 10.L.157.228; 10.L.157.229; 10.L.157.230; 10.L.157.231; 10.L.157.236; 10.L.157.237; 10X.157.238; 10X.157.239; 1Q.L.157.154; 10.L.157.157; 10.L.157.166; 10.L.157.169; IO.L.157.172; 10.L.157.175; 10.L.157.240; 10.L.157.244; 10.L.166.228; 10.L.166.229; 10.L.166.230; 10.L.166.231; 10.L.166.236; 10.L.166.237; 10.L.166.238; 10.L.166.239; 10.L.166.154; 10.L.166.157; 10.L.166.166; 10X.166.169; 10.L.166.172; 10.L.166.175; 10X.166.240; 10.L.166.244; 10.L.169.228; 10.L.169.229; 10.L.169.230; 10.L.169.231; 1QX.169.236; 10.L.169.237; 10.L.169.238; 10.L.169.239; 10.L.169.154; 10.L.169.157; 10.L.169.166; 10.L.169.169; 10.L.169.172; 10.L.169.175; 10.L.169.240; 10.L.169.244; 10.L.172.228; 10.L.172.229; 10.L.172.230; 10.L.172.231; 10.L.172.236; 10.L.172.237; 10.L.172.238; 10.L.172.239; IO.L.172.154; 10.L.172.157; 10.L.172.166; 10.L.172.169; IO.L.172.172; 10.L.172.175; 10.L.172.240; 10X.172.244; 10X.175.228; 10.L.175.229; 10X.175.230; 10X175.231; 10X.175.236; 10X.175.237; 10X.175.238; 10X.175.239; 10X.175.154; 10X.175.157; 10.L.175.166; 10X175.169; 10X.175.172; 10X.175.175; 10X.175.240; 10X.175.244; 10X.240.228; 10X.240.229; 10X.240.230; 10X.240.231; 10X.240.236; 10X.240.237; 1QX.240.238; 10X.240.239; 10X.240.154; 10X.240.157; 10X.240.166; 10X.240.169; 10X.240.172; 10X.240.175; 10X.240.240; 10X.240.244; 10X.244.228; 10X.244.229; 10X.244.230; 10X.244.231; 10X.244.236; 10X.244.237; 10X.244.238; 10X.244.239; 10X.244.154; 10X.244.157; 10X.244.166; 10X.244.169; 10X.244.172; 10X.244.175; 10X.244.240; 10X.244.244;

Prodrugs of lO.O

10.O.228.228; 10.O.228.229; 1Q.O.228.230; 10.O.228.231; 10.O.228.236; 10.O.228.237; 10.O.228.238; 10.O.228.239; 10.O.228.154; 10.O.228.157; 10.O.228.166; 10.O.228.169; 10.O.228.172; 10.O.228.175; 10.O.228.240; 10.O.228.244; 10.O.229.228; 10.O.229.229; 10.O.229.230; 10.O.229.231; 10.O.229.236; 10.O.229.237; 10.O.229.238; 10.O.229.239; 10.O.229.154; 10.O.229.157; 10.O.229.166; 10.O.229.169; 10.O.229.172; 10.O.229.175; 10.O.229.240; 10.O.229.244; 10.O.230.228; 10.O.230.229; 10.O.230.230; 10.O.230.231; 10.O.230.236; 10.O.230.237; 10.O.230.238; 10.O.230.239; 10.O.230.154; 10.O.230.157; 10.O.230.166; 10.O.230.169; 10.O.230.172; 10.O.230.175; 10.O.230.240; 10.O.230.244; 10.O.231.228; 10.O.231.229; 10.O.231.230; 10.O.231.231; 10.O.231.236; 10.O.231.237; 10.O.231.238; 10.O.231.239; 10.O.231.154; 10.O.231.157; 10.O.231.166; 10.O.231.169; 10.O.231.172; 10.O.231.175; 10.O.231.240; 10.O.231.244; 10.O.236.228; 10.O.236.229; 10.O.236.230; 10.O.236.231; 10.O.236.236; 10.O.236.237; 10.O.236.238; 10.O.236.239; 10.O.236.154; 10.O.236.157; 10.O.236.166; 10.O.236.169; 10.O.236.172; 10.O.236.175; 10.O.236.240; 10.O.236.244; 10.O.237.228; 10.O.237.229; 10.O.237.230; 10.O.237.231; 10.O.237.236; 10.O.237.237; 10.O.237.238; 10.O.237.239; 10.O.237.154; 10.O.237.157; 10.O.237.166; 10.O.237.169; 10.O.237.172; 10.O.237.175; 10.O.237.240; 10.O.237.244; 10.O.238.228; 10.O.238.229; 10.O.238.230; 10.O.238.231; 10.O.238.236; 10.O.238.237; 10.O.238.238; 10.O.238.239; 10.O.238.154; 10.O.238.157; 10.O.238.166; 10.O.238.169; 10.O.238.172; 10.O.238.175; 10.O.238.240; 10.O.238.244; 10.O.239.228; 10.O.239.229; 10.O.239.230; 10.O.239.231; 10.O.239.236; 10.O.239.237; 10.O.239.238; 10.O.239.239; 10.O.239.154; 10.O.239.157; 10.O.239.166; 10.O.239.169; 10.O.239.172; 10.O.239.175; 10.O.239.240; 10.O.239.244; 10.O.154.228; 10.O.154.229; 10.O.154.230; 10.O.154.231; 10.O.154.236; 10.O.154.237; 10.O.154.238; 10.O.154.239; 10.O.154.154; 10.O.154.157; 10.O.154.166; 10.O.154.169; 10.O.154.172; 10.O.154.175; 10.O.154.240; 10.O.154.244; 10.O.157.228; 10.O.157.229; 10.O.157.230; 10.O.157.231; 10.O.157.236; 10.O.157.237; 10.O.157.238; 10.O.157.239; 10.Q.157.154; 10.O.157.157; 10.O.157.166; 10.CU57.169; 10.O.157.172; 10.O.157.175; 10.O.157.240; 10.O.157.244; 10.O.166.228; 10.O.166.229; 10.O.166.230; 10.O.166.231; 10.O.166.236; 10.O.166.237; 10.O.166.238; 10.O.166.239; 10.O.166.154; 10.O.166.157; 10.O.166.166; 10.O.166.169; 10.O.166.172; 10.O.166.175; 10.O.166.240; 10.O.166.244; 10.O.169.228; 10.O.169.229; 10.O.169.230; 10.O.169.231; 10.O.169.236; 10.O.169.237; 10.O.169.238; 10.O.169.239; 10.O.169.154; 1Q.O.169.157; 10.O.169.166; 10.O.169.169; 10.O.169.172; 10.O.169.175; 10.O.169.240; 10.O.169.244; 10.O.172.228; 10.O.172.229; 10.O.172.230; 10.O.172.231; 10.O.172.236; 10.O.172.237; 10.O.172.238; 10.O.172.239; 10.O.172.154; 10.O.172.157; 10.O.172.166; 10.O.172.169; 10.O.172.172; 10.O.172.175; 10.O.172.240; 10.O.172.244; 10.O.175.228; 10.O.175.229; 10.O.175.230; 10.O.175.231; 10.O.175.236; 10.O.175.237; 10.O.175.238; 10.O.175.239; 10.O.175.154; 10.O.175.157; 10.O.175.166; 10.O.175.169; 10.O.175.172; 10.O.175.175; 10.Q.175.240; 10.O.175.244; 10.O.240.228; 10.O.240.229; 10.O.240.230; 10.O.24Q.231; 10.O.240.236; 10.O.240.237; 10.O.240.238; 10.O.240.239; 10.O.240.154; 1Q.O.240.157; 10.Q.240.166; 10.O.240.169; 10.O.240.172; 1Q.O.240.175; 10.O.240.240; 10.O.240.244; 10.O.244.228; 10.O.244.229; 1Q.O.244.230; 10.O.244.231; 10.O.244.236; 10.O.244.237; 10.O.244.238; 10.O.244.239; 1Q.O.244.154; 10.O.244.157; 10.O.244.166; 10.O.244.169; 10.O.244.172; 10.O.244.175; 10.O.244.240; 10.O.244.244;

Prodrugs of 10.P

10.P.228.228; 10.P.228.229; 10.P.228.230; 10.P.228.231; 10.P.228.236; 10.P.228.237; 10.P.228.238; 10.P.228.239; 10.P.228.154; 10.P.228.157; 10.P.228.166; 10.P.228.169; 10.P.228.172; 10.P.228.175; 10.P.228.240; 10.P.228.244; 10.P.229.228; 10.P.229.229; 10.P.229.230; 10.P.229.231; 10.P.229.236; 10.P.229.237; 10.P.229.238; 10.P.229.239; 10.P.229.154; 10.P.229.157; 10.P.229.166; 10.P.229.169; 10.P.229.172; 10.P.229.175; 10.P.229.240; 10.P.229.244; 10.P.230.228; 10.P.230.229; 10.P.230.230; 10.P.230.231; 10.P.230.236; 10.P.230.237; 10.P.230.238; 10.P.230.239; 10.P.230.154; 10.P.230.157; 10.P.230.166; 10.P.230.169; 10.P.230.172; 10.P.230.175; 10.P.230.240; 10.P.230.244; 10.P.231.228; 10.P.231.229; 10.P.231.23Q; 10.P.231.231; 10.P.231.236; IO.P.231.237; 10.P.231.238; 10.P.231.239; 10.P.231.154; 10.P.231.157; 10.P.231.166; 10.P.231.169; 10.P.231.172; 10.P.231.175; 10.P.231.240; 10.P.231.244; 10.P.236.228; 10.P.236.229; 10.P.236.230; 10.P.236.231; 10.P.236.236; 10.P.236.237; 10.P.236.238; 10.P.236.239; 10.P.236.154; 1Q.P.236.157; 10.P.236.166; 10.P.236.169; 10.P.236.172; 10.P.236.175; 10.P.236.240; 10.P.236.244; 10.P.237.228; 10.P.237.229; 10.P.237.230; 10.P.237.231; 10.P.237.236; 10.P.237.237; 10.P.237.238; 10.P.237.239; 10.P.237.154; 10.P.237.157; 10. P.237.166; 10.P.237.169; 10.P.237.172; 10.P.237.175; 10.P.237.240; 10.P.237.244; 10.P.238.228; 10.P.238.229; 10.P.238.230; 10.P.238.231; 10.P.238.236; 10.P.238.237; 10.P.238.238; 10.P.238.239; 1Q.P.238.154; 10.P.238.157; 10.P.238.166; 10.P.238.169; 10.P.238.172; 10.P.238.175; 10.P.238.240; 10.P.238.244; 10.P.239.228; 10.P.239.229; 10.P.239.230; 10.P.239.231; 10.P.239.236; 10.P.239.237; 10.P.239.238; 10.P.239.239; 10.P.239.154; 1Q.P.239.157; 10.P.239.166; 10.P.239.169; 10.P.239.172; 10.P.239.175; 10.P.239.240; 10.P.239.244; 10.P.154.228; 10.P.154.229; 10.P.154.230; 10.P.154.231; 10.P.154.236; 10.P.154.237; 10.P.154.238; 10.P.154.239; 1Q.P.154.154; 10.P.154.157; 10.P.154.166; 10.P.154.169; 10.P.154.172; 10.P.154.175; 10.P.154.240; 10.P.154.244; 10.P.157.228; 10.P.157.229; 10.P.157.230; 10.P.157.231; 1Q.P.157.236; 10.P.157.237; 10.P.157.238; 10.P.157.239; 10.P.157.154; 10.P.157.157; 10.P.157.166; 10.P.157.169; 10.P.157.172; 10.P.157.175; 10.P.157.240; 10.P.157.244; 10.P.166.228; 10.P.166.229; 10.P.166.230; 10.P.166.231; 10.P.166.236; 10.P.166.237; 10.P.166.238; 10.P.166.239; 10.P.166.154; 10.P.166.157; 10.P.166.166; 10.P.166.169; 10.P.166.172; 10.P.166.175; 10.P.166.240; 10.P.166.244; 10.P.169.228; 10.P.169.229; 10.P.169.230; 10.P.169.231; 10.P.169.236; 10.P.169.237; 10.P.169.238; 10.P.169.239; 10.P.169.154; 10.P.169.157; 10.P.169.166; 10.P.169.169; 10.P.169.172; 10.P.169.175; 10.P.169.240; 10.P.169.244; 10.P.172.228; 10.P.172.229; IO.P.172.230; 10.P.172.231; 10.P.172.236; 10.P.172.237; 10.P.172.238; 10.P.172.239; 10.P.172.154; 10.P.172.157; 10.P.172.166; 10.P.172.169; IO.P.172.172; 10.P.172.175; 10.P.172.240; 10.P.172.244; 10.P.175.228; 10.P.175.229; 10.P.175.230; 10.P.175.231; 10.P.175.236; 10.P.175.237; 10.P.175.238; 10.P.175.239; 10.P.175.154; 10.P.175.157; 10.P.175.166; 10.P.175.169; 10.P.175.172; 10.P.175.175; 10.P.175.240; 10.P.175.244; 10.P.240.228; 10.P.240.229; 10.P.240.230; 10.P.240.231; 10.P.240.236; 10.P.240.237; 10.P.240.238; 10.P.240.239; 1Q.P.240.154; 10.P.240.157; 10.P.240.166; 10.P.240.169; 10.P.240.172; 10.P.240.175; 10.P.240.240; 10.P.240.244; 10.P.244.228; 10.P.244.229; 10.P.244.230; 10.P.244.231; 10.P.244.236; 10.P.244.237; 10.P.244.238; 10.P.244.239; 10.P.244.154; 10.P.244.157; 10.P.244.166; 10.P.244.169; 10.P.244.172; 10.P.244.175; 10.P.244.240; 10.P.244.244;

Prodrugs of 10.U

10.U.228.228; 10.U.228.229; 10.U.228.230; 10.U.228.231; 10.U.228.236; 10.U.228.237; 10.U.228.238; 10.U.228.239; 10.U.228.154; 10.U.228.157; 10.U.228.166; 10.U.228.169; 10.U.228.172; 10.U.228.175; 10.U.228.240; 10.U.228.244; 10.U.229.228; 10.U.229.229; 10.U.229.230; 10.U.229.231; 10.U.229.236; 10.U.229.237; 10.U.229.238; 10.U.229.239; 10.U.229.154; 10.U.229.157; 10.U.229.166; 10.U.229.169; 10.U.229.172; 10.U.229.175; 10.U.229.240; 10.U.229.244; 10.U.230.228; 10.U.230.229; 10.U.230.230; 10.U.230.231; 10.U.230.236; 10.U.230.237; 10.U.230.238; 10.U.230.239; 10.U.230.154; 10.U.230.157; 10.U.230.166; 10.U.230.169; 10.U.230.172; 10.U.230.175; 10.U.230.240; 10.U.230.244; 10.U.231.228; 10.U.231.229; 10.U.231.230; 10.U.231.231; 10.U.231.236; 10.U.231.237; 10.U.231.238; 10.U.231.239; 10.U.231.154; 10.U.231.157; 10.U.231.166; 10.U.231.169; 10.U.231.172; 10.U.231.175; 10.U.231.240; 10.U.231.244; 10.U.236.228; 10.U.236.229; 10.U.236.230; 10.U.236.231; 10.U.236.236; 10.U.236.237; 10.U.236.238; 10.U.236.239; 10.U.236.154; 10.U.236.157; 10.U.236.166; 10.U.236.169; 10.U.236.172; 10.U.236.175; 10.U.236.240; 10.U.236.244; 10.U.237.228; 10.U.237.229; 10.U.237.230; 10.U.237.231; 10.U.237.236; 10.U.237.237; 10.U.237.238; 10.U.237.239; 10.U.237.154; 10.U.237.157; 10.U.237.166; 10.U.237.169; 10.U.237.172; 1Q.U.237.175; 10.U.237.240; 10.U.237.244; 10.U.238.228; 10.U.238.229; 10.U.238.230; 10.U.238.231; 10.U.238.236; 10.U.238.237; 10.U.238.238; 10.U.238.239; 10.U.238.154; 10.U.238.157; 10.U.238.166; 10.U.238.169; 10.U.238.172; 10.U.238.175; 10.U.238.240; 10.U.238.244; 10.U.239.228; 10.U.239.229; 10.U.239.230; 10.U.239.231; 10.U.239.236; 10.U.239.237; 10.U.239.238; 10.U.239.239; 10.U.239.154; 10.U.239.157; 10.U.239.166; 10.U.239.169; 10.U.239.172; 10.U.239.175; 10.U.239.240; 10.U.239.244; 10.U.154.228; 10.U.154.229; 10.U.154.230; 10.U.154.231; 10.U.154.236; 10.U.154.237; 10.U.154.238; 10.U.154.239; 10.U.154.154; 10.U.154.157; 10.U.154.166; 10.U.154.169; 10.U.154.172; 10.U.154.175; 10.U.154.240; 10.U.154.244; 10.U.157.228; 10.U.157.229; 10.U.157.230; 10.U.157.231; 10.U.157.236; 10.U.157.237; 10.U.157.238; 10.U.157.239; 10.U.157.154; 10.U.157.157; 10.U.157.166; 10.U.157.169; 10.U.157.172; 10.U.157.175; 10.U.157.240; 10.U.157.244; 10.U.166.228; 10.U.166.229; 10.U.166.230; 10.U.166.231; 10.U.166.236; 10.U.166.237; 10.U.166.238; 1Q.U.166.239; 10.U.166.154; 10.U.166.157; 10.U.166.166; 10.U.166.169; 10.U.166.172; 10.U.166.175; 10.U.166.240; 10.U.166.244; 10.U.169.228; 10.U.169.229; 10.U.169.230; 10.U.169.231; 10.U.169.236; 10.U.169.237; 1Q.U.169.238; 10.U.169.239; 1Q.U.169.154; 10.U.169.157; 10.U.169.166; 10.U.169.169; 10.U.169.172; 10.U.169.175; 10.U.169.240; 10.U.169.244; 10.U.172.228; 10.U.172.229; 10.U.172.230; 10.U.172.231; 10.U.172.236; 10.U.172.237; 10.U.172.238; 10.U.172.239; 10.U.172.154; 10.U.172.157; 10.U.172.166; 10.U.172.169; 10.U.172.172; 10.U.172.175; 10.U.172.240; 10.U.172.244; 10.U.175.228; 10.U.175.229; 10.U.175.230; 10.U.175.231; 1Q.U.175.236; 10.U.175.237; 10.U.175.238; 10.U.175.239; 10.U.175.154; 10.U.175.157; 10.U.175.166; 1Q.U.175.169; 10.U.175.172; 10.U.175.175; 10.U.175.240; 10.U.175.244; 10.U.240.228; 10.U.240.229; 10.U.240.230; 10.U.24Q.231; 10.U.240.236; 10.U.240.237; 10.U.240.238; 10.U.240.239; 10.U.240.154; 10.U.240.157; 10.U.240.166; 10.U.240.169; 10.U.240.172; 10.U.240.175; 10.U.240.240; 10.U.240.244; 10.U.244.228; 10.U.244.229; 10.U.244.230; 10.U.244.231; 10.U.244.236; 10.U.244.237; 10.U.244.238; 10.U.244.239; 10.U.244.154; 10.U.244.157; 10.U.244.166; 10.U.244.169; 10.U.244.172; 10.U.244.175; 10.U.244.240; 10.U.244.244;

Prodrugs of 10.CD

IO.CD.228.228; IO.CD.228.229; IO.CD.228.230; IO.CD.228.231; IO.CD.228.236; IO.CD.228.237; IO.CD.228.238; IO.CD.228.239; IO.CD.228.154; IO.CD.228.157; IO.CD.228.166; IO.CD.228.169; IO.CD.228.172; IO.CD.228.175; IO.CD.228.240; IO.CD.228.244; IO.CD.229.228; IO.CD.229.229; IO.CD.229.230; IO.CD.229.231; IO.CD.229.236; IO.CD.229.237; IO.CD.229.238; IO.CD.229.239; IO.CD.229.154; IO.CD.229.157; IO.CD.229.166; IO.CD.229.169; IO.CD.229.172; IO.CD.229.175; IO.CD.229.240; IO.CD.229.244; IO.CD.230.228; IO.CD.230.229; IO.CD.230.230; IO.CD.230.231; IO.CD.230.236; IO.CD.230.237; IO.CD.230.238; IO.CD.230.239; IO.CD.230.154; IO.CD.230.157; IO.CD.230.166; IO.CD.230.169; IO.CD.230.172; IO.CD.230.175; 10.CD.230.24Q; IO.CD.230.244; IO.CD.231.228; IO.CD.231.229; IO.CD.231.230; IO.CD.231.231; IO.CD.231.236; IO.CD.231.237; IO.CD.231.238; IO.CD.231.239; IO.CD.231.154; IO.CD.231.157; IO.CD.231.166; IO.CD.231.169; 10.CU231.172; IO.CD.231.175; IQ.CD.231.240; IO.CD.231.244; IO.CD.236.228; IO.CD.236.229; IO.CD.236.230; IO.CD.236.231; IO.CD.236.236; IO.CD.236.237; IO.CD.236.238; IO.CD.236.239; IO.CD.236.154; IO.CD.236.157; IO.CD.236.166; IO.CD.236.169; IO.CD.236.172; IO.CD.236.175; IO.CD.236.240; IO.CD.236.244; IO.CD.237.228; IO.CD.237.229; IO.CD.237.230; IO.CD.237.231; IO.CD.237.236; IO.CD.237.237; IO.CD.237.238; IO.CD.237.239; IO.CD.237.154; IO.CD.237.157; IO.CD.237.166; IO.CD.237.169; IO.CD.237.172; IO.CD.237.175; IO.CD.237.240; IO.CD.237.244; IO.CD.238.228; IO.CD.238.229; IO.CD.238.230; IO.CD.238.231; IO.CD.238.236; IO.CD.238.237; IO.CD.238.238; IO.CD.238.239; IO.CD.238.154; IO.CD.238.157; IO.CD.238.166; IO.CD.238.169; 1Q.CD.238.172; IO.CD.238.175; IO.CD.238.240; IO.CD.238.244; IO.CD.239.228; IO.CD.239.229; IO.CD.239.230; IO.CD.239.231; IO.CD.239.236; IQ.CD.239.237; IO.CD.239.238; IO.CD.239.239; IO.CD.239.154; IO.CD.239.157; IO.CD.239.166; IO.CD.239.169; IO.CD.239.172; IO.CD.239.175; IO.CD.239.240; IO.CD.239.244; IO.CD.154.228; IO.CD.154.229; IO.CD.154.230; IO.CD.154.231; IO.CD.154.236; IO.CD.154.237; IO.CD.154.238; IO.CD.154.239; IO.CD.154.154; IO.CD.154.157; IO.CD.154.166; IO.CD.154.169; IO.CD.154.172; IO.CD.154.175; IQ.CD.154.240; IO.CD.154.244; IO.CD.157.228; IO.CD.157.229; IO.CD.157.230; IO.CD.157.231; IO.CD.157.236; IO.CD.157.237; IO.CD.157.238; IO.CD.157.239; IO.CD.157.154; IO.CD.157.157; IO.CD.157.166; IO.CD.157.169; IO.CD.157.172; IO.CD.157.175; IO.CD.157.240; IO.CD.157.244; IO.CD.166.228; IO.CD.166.229; 1Q.CD.166.23Q; IO.CD.166.231; IO.CD.166.236; IO.CD.166.237; IO.CD.166.238; IO.CD.166.239; IO.CD.166.154; IO.CD.166.157; IO.CD.166.166; IO.CD.166.169; IO.CD.166.172; IO.CD.166.175; IO.CD.166.240; IO.CD.166.244; IO.CD.169.228; IO.CD.169.229; IO.CD.169.230; IO.CD.169.231; IO.CD.169.236; IO.CD.169.237; IO.CD.169.238; IO.CD.169.239; IO.CD.169.154; IO.CD.169.157; IO.CD.169.166; IQ.CD.169.169; IO.CD.169.172; IO.CD.169.175; IO.CD.169.240; IO.CD.169.244; IO.CD.172.228; IO.CD.172.229; IO.CD.172.230; IO.CD.172.231; IO.CD.172.236; IO.CD.172.237; IO.CD.172.238; IO.CD.172.239; IO.CD.172.154; IO.CD.172.157; IO.CD.172.166; IO.CD.172.169; IO.CD.172.172; IO.CD.172.175; IO.CD.172.240; IO.CD.172.244; IO.CD.175.228; IO.CD.175.229; IO.CD.175.230; IO.CD.175.231; IO.CD.175.236; IO.CD.175.237; IO.CD.175.238; IO.CD.175.239; IO.CD.175.154; IO.CD.175.157; IO.CD.175.166; IO.CD.175.169; IO.CD.175.172; IO.CD.175.175; IO.CD.175.240; IO.CD.175.244; IO.CD.240.228; IO.CD.240.229; IO.CD.240.230; IO.CD.240.231; IO.CD.240.236; IO.CD.240.237; IO.CD.240.238; IO.CD.240.239; IO.CD.240.154; IO.CD.240.157; IO.CD.240.166; IO.CD.240.169; 10. CD.240.172; IO.CD.240.175; IO.CD.240.240; IO.CD.240.244; IO.CD.244.228; IO.CD.244.229; IO.CD.244.230; IO.CD.244.231; IO.CD.244.236; IO.CD.244.237; IO.CD.244.238; IO.CD.244.239; IO.CD.244.154; IO.CD.244.157; IO.CD.244.166; IO.CD.244.169; IO.CD.244.172; IO.CD.244.175; IO.CD.244.240; IO.CD.244.244;

Prodrugs of 10.EB

10.EB.228.228; 10.EB.228.229; 10.EB.228.230; 10.EB.228.231; 10.EB.228.236; 10.EB.228.237; 10.EB.228.238; 10.EB.228.239; 10.EB.228.154; 10.EB.228.157; 10.EB.228.166; 10.EB.228.169; 10.EB.228.172; 10.EB.228.175; 10.EB.228.240; 10.EB.228.244; 10.EB.229.228; 10.EB.229.229; 10.EB.229.230; 10.EB.229.231; 10.EB.229.236; 10.EB.229.237; 10.EB.229.238; 1Q.EB.229.239; 10.EB.229.154; 10.EB.229.157; 10.EB.229.166; 10.EB.229.169; 10.EB.229.172; 10.EB.229.175; 10.EB.229.240; 10.EB.229.244; 10.EB.230.228; 10.EB.230.229; 10.EB.230.230; 10.EB.230.231; 10.EB.230.236; 10.EB.230.237; 10.EB.230.238; 10.EB.230.239; 10.EB.230.154; 10.EB.230.157; 10.EB.230.166; 10.EB.230.169; 10.EB.230.172; 10.EB.230.175; 1Q.EB.230.240; 10.EB.230.244; 10.EB.231.228; 10.EB.231.229; 10.EB.231.230; 10.EB.231.231; 10.EB.231.236; 10.EB.231.237; 10.EB.231.238; 10.EB.231.239; 10.EB.231.154; 10.EB.231.157; 10.EB.231.166; 10.EB.231.169; 10.EB.231.172; 10.EB.231.175; 10.EB.231.240; 10. EB.231.244; 10.EB.236.228; 10.EB.236.229; 10.EB.236.230; 10.EB.236.231; 10.EB.236.236; 10.EB.236.237; 10.EB.236.238; 10.EB.236.239; 10.EB.236.154; 10.EB.236.157; 10.EB.236.166; 10.EB.236.169; 10.EB.236.172; IO.EB.236.175; 10.EB.236.240; 10.EB.236.244; 10.EB.237.228; 10.EB.237.229; 10.EB.237.230; 10.EB.237.231; 10.EB.237.236; 10.EB.237.237; 10.EB.237.238; 1Q.EB.237.239; 10.EB.237.154; 10.EB.237.157; 10.EB.237.166; 10.EB.237.169; 10.EB.237.172; 10.EB.237.175; 10.EB.237.240; 10.EB.237.244; 10.EB.238.228; 10.EB.238.229; 10-EB.238.230; 10.EB.238.231; 10.EB.238.236; 10.EB.238.237; 10.EB.238.238; 10.EB.238.239; 10.EB.238.154; 10.EB.238.157; 10.EB.238.166; 10.EB.238.169; 10.EB.238.172; 10.EB.238.175; 10.EB.238.240; 10.EB.238.244; 10.EB.239.228; 10.EB.239.229; 10.EB.239.230; 10.EB.239.231; 10.EB.239.236; 10.EB.239.237; 10.EB.239.238; 10.EB.239.239; 10.EB.239.154; 10.EB.239.157; 10.EB.239.166; 10.EB.239.169; 10.EB.239.172; 10.EB.239.175; 10.EB.239.240; 10.EB.239.244; 10.EB.154.228; 10.EB.154.229; 10.EB.154.230; 10.EB.154.231; 10.EB.154.236; 10.EB.154.237; 10.EB.154.238; 10.EB.154.239; 10.EB.154.154; 10.EB.154.157; 10.EB.154.166; 10.EB.154.169; 10.EB.154.172; 10.EB.154.175; 10.EB.154.240; 10.EB.154.244; 10.EB.157.228; 10.EB.157.229; 10.EB.157.230; 10.EB.157.231; 10.EB.157.236; 10.EB.157.237; 10.EB.157.238; 10.EB.157.239; 10.EB.157.154; 10.EB.157.157; 10.EB.157.166; 10.EB.157.169; 10.EB.157.172; 10.EB.157.175; 10.EB.157.240; 10.EB.157.244; 10.EB.166.228; 10.EB.166.229; 10.EB.166.230; 10.EB.166.231; 10.EB.166.236; 10.EB.166.237; 10.EB.166.238; 10.EB.166.239; 10.EB.166.154; 10.EB.166.157; 10.EB.166.166; 10.EB.166.169; 10.EB.166.172; 10.EB.166.175; 10.EB.166.240; 10.EB.166.244; 10.EB.169.228; 10.EB.169.229; 10.EB.169.230; 10.EB.169.231; 10.EB.169.236; 10.EB.169.237; 10.EB.169.238; 10.EB.169.239; 10.EB.169.154; 10.EB.169.157; 10.EB.169.166; 10.EB.169.169; 10.EB.169.172; 10.EB.169.175; 10.EB.169.240; 10.EB.169.244; 10.EB.172.228; 10. EB.172.229; 10.EB.172.230; 10.EB.172.231; 10.EB.172.236; 10.EB.172.237; 10.EB.172.238; 10.EB.172.239; 10.EB.172.154; 10.EB.172.157; 10.EB.172.166; 10.EB.172.169; 10.EB.172.172; 10.EB.172.175; 10.EB.172.240; 10.EB.172.244; 10.EB.175.228; 10. EB.175.229; 10.EB.175.230; 10.EB.175.231; 10.EB.175.236; 10.EB.175.237; 10.EB.175.238; 10.EB.175.239; 10.EB.175.154; 10.EB.175.157; 10.EB.175.166; 10.EB.175.169; 10.EB.175.172; 10.EB.175.175; 10.EB.175.24Q; 10.EB.175.244; 10.EB.240.228; 10.EB.240.229; 10.EB.240.230; 10.EB.240.231; 10.EB.240.236; 10.EB.240.237; 10.EB.240.238; 10.EB.240.239; 10.EB.240.154; 10.EB.240.157; 10.EB.240.166; 10.EB.240.169; 10.EB.240.172; 10.EB.240.175; 10. EB.240.240; 10.EB.240.244; 10.EB.244.228; 10.EB.244.229; 10.EB.244.230; 10.EB.244.231; 10.EB.244.236; 10.EB.244.237; 10.EB.244.238; 10.EB.244.239; 10.EB.244.154; 10.EB.244.157; 10.EB.244.166; 10.EB.244.169; 10.EB.244.172; 10.EB.244.175; 10.EB.244.240; 10.EB.244.244;

Prodrugs of 11. B ll.B.228.228; ll.B.228.229; ll.B.228.230; ll.B.228.231; ll.B.228.236; ll.B.228.237; ll.B.228.238; ll.B.228.239; ll.B.228.154; ll.B.228.157; ll.B.228.166; ll.B.228.169; ll.B.228.172; ll.B.228.175; ll.B.228.240; ll.B.228.244; ll.B.229.228; ll.B.229.229; ll.B.229.230; ll.B.229.231; ll.B.229.236; ll.B.229.237; ll.B.229.238; ll.B.229.239; ll.B.229.154; ll.B.229.157; ll.B.229.166; ll.B.229.169; ll.B.229.172; ll.B.229.175; ll.B.229.240; ll.B.229.244; ll.B.230.228; ll.B.230.229; ll.B.230.230; ll.B.230.231; ll.B.230.236; ll.B.230.237; ll.B.230.238; ll.B.230.239; ll.B.230.154; ll.B.230.157; ll.B.230.166; ll.B.230.169; ll.B.230.172; ll.B.230.175; ll.B.230.240; ll.B.230.244; ll.B.231.228; ll.B.231.229; ll.B.231.230; ll.B.231.231; ll.B.231.236; ll.B.231.237; ll.B.231.238; ll.B.231.239; ll.B.231.154; ll.B.231.157; ll.B.231.166; ll.B.231.169; ll.B.231.172; ll.B.231.175; ll.B.231,240; ll.B.231.244; ll.B.236.228; ll.B.236.229; ll.B.236.230; ll.B.236.231; ll.B.236.236; ll.B.236.237; ll.B.236.238; ll.B.236.239; ll.B.236.154; ll.B.236.157; ll.B.236.166; ll.B.236.169; ll.B.236.172; ll.B.236.175; ll.B.236.240; ll.B.236.244; ll.B.237.228; ll.B.237.229; ll.B.237.230; ll.B.237.231; ll.B.237.236; ll.B.237.237; ll.B.237.238; ll.B.237.239; ll.B.237.154; ll.B.237.157; ll.B.237.166; ll.B.237.169; ll.B.237.172; ll.B.237.175; ll.B.237.240; ll.B.237.244; ll.B.238.228; ll.B.238.229; ll.B.238.230; ll.B.238.231; ll.B.238.236; ll.B.238.237; ll.B.238.238; ll.B.238.239; ll.B.238.154; ll.B.238.157; ll.B.238.166; ll.B.238.169; ll.B.238.172; ll.B.238.175; ll.B.238.240; ll.B.238.244; ll.B.239.228; ll.B.239.229; ll.B.239.230; ll.B.239.231; ll.B.239.236; ll.B.239.237; ll.B.239.238; ll.B.239.239; ll.B.239.154; ll.B.239.157; ll.B.239.166; ll.B.239.169; ll.B.239.172; ll.B.239.175; ll.B.239.240; ll.B.239.244; ll.B.154.228; ll.B.154.229; ll.B.154.230; ll.B.154.231; ll.B.154.236; ll.B.154.237; ll.B.154.238; ll.B.154.239; ll.B.154.154; ll.B.154.157; ll.B.154.166; ll.B.154.169; ll.B.154.172; ll.B.154.175; ll.B.154.240; ll.B.154.244; ll.B.157.228; ll.B.157.229; ll.B.157.230; ll.B.157.231; ll.B.157.236; ll.B.157.237; ll.B.157.238; ll.B.157.239; ll.B.157.154; ll.B.157.157; ll.B.157.166; ll.B.157.169; ll.B.157.172; ll.B.157.175; ll.B.157.240; ll.B.157.244; ll.B.166.228; ll.B.166.229; ll.B.166.230; ll.B.166.231; ll.B.166.236; ll.B.166.237; ll.B.166.238; ll.B.166.239; ll.B.166.154; ll.B.166.157; ll.B.166.166; ll.B.166.169; ll.B.166.172; ll.B.166.175; ll.B.166.240; ll.B.166.244; ll.B.169.228; ll.B.169.229; ll.B.169.230; ll.B.169.231; ll.B.169.236; ll.B.169.237; ll.B.169.238; ll.B.169.239; ll.B.169.154; ll.B.169.157; ll.B.169.166; ll.B.169.169; ll.B.169.172; ll.B.169.175; ll.B.169.240; ll.B.169.244; ll.B.172.228; ll.B.172.229; ll.B.172.230; ll.B.172.231; ll.B.172.236; ll.B.172.237; ll.B.172.238; ll.B.172.239; ll.B.172.154; ll.B.172.157; ll.B.172.166; ll.B.172.169; ll.B.172.172; ll.B.172.175; ll.B.172.240; ll.B.172.244; ll.B.175.228; ll.B.175.229; ll.B.175.230; ll.B.175.231; ll.B.175.236; ll.B.175.237; ll.B.175.238; ll.B.175.239; ll.B.175.154; ll.B.175.157; ll.B.175.166; ll.B.175.169; ll.B.175.172; ll.B.175.175; ll.B.175.240; ll.B.175.244; ll.B.240.228; ll.B.240.229; ll.B.240.230; ll.B.240.231; ll.B.240.236; ll.B.240.237; ll.B.240.238; ll.B.240.239; ll.B.240.154; ll.B.240.157; ll.B.240.166; ll.B.240.169; ll.B.240.172; ll.B.240.175; ll.B.240.240; ll.B.240.244; ll.B.244.228; ll.B.244.229; ll.B.244.230; ll.B.244.231; ll.B.244.236; ll.B.244.237; ll.B.244.238; ll.B.244.239; ll.B.244.154; ll.B.244.157; ll.B.244.166; ll.B.244.169; ll.B.244.172; ll.B.244.175; ll.B.244.240; ll.B.244.244;

Prodrugs of 11. D ll.D.228.228; ll.D.228.229; ll.D.228.230; ll.D.228.231; ll.D.228.236; ll.D.228.237; ll.D.228.238; ll.D.228.239; ll.D.228.154; ll.D.228.157; ll.D.228.166; ll.D.228.169; ll.D.228.172; ll.D.228.175; ll.D.228.240; ll.D.228.244; ll.D.229.228; ll.D.229.229; ll.D.229.230; ll.D.229.231; ll.D.229.236; ll.D.229.237; ll.D.229.238; ll.D.229.239; ll.D.229.154; ll.D.229.157; ll.D.229.166; ll.D.229.169; ll.D.229.172; ll.D.229.175; ll.D.229.240; ll.D.229.244; ll.D.230.228; ll.D.230.229; ll.D.230.230; ll.D.230.231; ll.D.230.236; ll.D.230.237; ll.D.230.238; ll.D.230.239; ll.D.230.154; ll.D.230.157; ll.D.230.166; ll.D.230.169; ll.D.230.172; ll.D.230.175; ll.D.230.240; ll.D.230.244; ll.D.231.228; ll.D.231.229; ll.D.231.230; ll.D.231.231; ll.D.231.236; ll.D.231.237; ll.D.231.238; ll.D.231.239; ll.D.231.154; ll.D.231.157; ll.D.231.166; ll.D.231.169; ll.D.231.172; ll.D.231.175; ll.D.231.240; ll.D.231.244; ll.D.236.228; ll.D.236.229; ll.D.236.230; ll.D.236.231; ll.D.236.236; ll.D.236.237; ll.D.236.238; ll.D.236.239; ll.D.236.154; ll.D.236.157; ll.D.236.166; ll.D.236.169; ll.D.236.172; ll.D.236.175; ll.D.236.240; ll.D.236.244; ll.D.237.228; ll.D.237.229; ll.D.237.230; ll.D.237.231; ll.D.237.236; ll.D.237.237; ll.D.237.238; ll.D.237.239; ll.D.237.154; ll.D.237.157; ll.D.237.166; ll.D.237.169; ll.D.237.172; ll.D.237.175; ll.D.237.240; ll.D.237.244; ll.D.238.228; ll.D.238.229; ll.D.238.230; ll.D.238.231; ll.D.238.236; ll.D.238.237; ll.D.238.238; ll.D.238.239; ll.D.238.154; ll.D.238.157; ll.D.238.166; ll.D.238.169; ll.D.238.172; ll.D.238.175; ll.D.238.240; ll.D.238.244; ll.D.239.228; ll.D.239.229; ll.D.239.230; ll.D.239.231; ll.D.239.236; ll.D.239.237; ll.D.239.238; ll.D.239.239; ll.D.239.154; ll.D.239.157; ll.D.239.166; ll.D.239.169; ll.D.239.172; ll.D.239.175; ll.D.239.240; ll.D.239.244; ll.D.154.228; ll.D.154.229; ll.D.154.230; ll.D.154.231; ll.D.154.236; ll.D.154.237; ll.D.154.238; ll.D.154.239; ll.D.154.154; ll.D.154.157; ll.D.154.166; ll.D.154.169; ll.D.154.172; ll.D.154.175; ll.D.154.240; ll.D.154.244; ll.D.157.228; ll.D.157.229; ll.D.157.230; ll.D.157.231; ll.D.157.236; ll.D.157.237; ll.D.157.238; ll.D.157.239; ll.D.157.154; ll.D.157.157; ll.D.157.166; ll.D.157.169; ll.D.157.172; ll.D.157.175; ll.D.157.240; ll.D.157.244; ll.D.166.228; ll.D.166.229; ll.D.166.230; ll.D.166.231; ll.D.166.236; ll.D.166.237; ll.D.166.238; ll.D.166.239; ll.D.166.154; ll.D.166.157; ll.D.166.166; ll.D.166.169; ll.D.166.172; ll.D.166.175; ll.D.166.240; ll.D.166.244; ll.D.169.228; ll.D.169.229; 11D.169.230; ll.D.169.231; ll.D.169.236; ll.D.169.237; ll.D.169.238; ll.D.169.239; ll.D.169.154; ll.D.169.157; ll.D.169.166; ll.D.169.169; ll.D.169.172; ll.D.169.175; ll.D.169.240; ll.D.169.244; ll.D.172.228; ll.D.172.229; ll.D.172.230; ll.D.172.231; ll.D.172.236; ll.D.172.237; ll.D.172.238; ll.D.172.239; ll.D.172.154; ll.D.172.157; ll.D.172.166; ll.D.172.169; ll.D.172.172; ll.D.172.175; ll.D.172.240; ll.D.172.244; ll.D.175.228; ll.D.175.229; ll.D.175.230; ll.D.175.231; ll.D.175.236; ll.D.175.237; ll.D.175.238; ll.D.175.239; ll.D.175.154; ll.D.175.157; ll.D.175.166; ll.D.175.169; ll.D.175.172; ll.D.175.175; ll.D.175.240; ll.D.175.244; ll.D.240.228; ll.D.240.229; ll.D.240.230; ll.D.240.231; ll.D.240.236; ll.D.240.237; ll.D.240.238; ll.D.240.239; ll.D.240.154; ll.D.240.157; ll.D.240.166; ll.D.240.169; ll.D.240.172; ll.D.240.175; ll.D.240.240; ll.D.240.244; ll.D.244.228; ll.D.244.229; ll.D.244.230; ll.D.244.231; ll.D.244.236; ll.D.244.237; ll.D.244.238; ll.D.244.239; ll.D.244.154; ll.D.244.157; ll.D.244.166; ll.D.244.169; ll.D.244.172; ll.D.244.175; ll.D.244.240; ll.D.244.244;

Prodrugs of 11.AB ll.AB.228.228; ll.AB.228.229; ll.AB.228.230; ll.AB.228.231; 11. AB.228.236; ll.AB.228.237; 11. AB.228.238; ll.AB.228.239; ll.AB.228.154; ll.AB.228.157; ll.AB.228.166; ll.AB.228.169; ll.AB.228.172; 11. AB.228.175; ll.AB.228.240; ll.AB.228.244; 11. AB.229.228; ll.AB.229.229; ll.AB.229.230; ll.AB.229.231; ll.AB.229.236; 11. AB.229.237; ll.AB.229.238; ll.AB.229.239; ll.AB.229.154; ll.AB.229.157; ll.AB.229.166; ll.AB.229.169; ll.AB.229.172; 11. AB .229.175; ll.AB.229.240; 11. AB.229.244; ll.AB.230.228; ll.AB.230.229; ll.AB.230.230; ll.AB.230.231; ll.AB.230.236; ll.AB.230.237; 11.AB.23Q.238; 11. AB .230.239; ll.AB.230.154; ll.AB.230.157; ll.AB.230.166; ll.AB.230.169; ll.AB.230.172; ll.AB.230.175; ll.AB.230.240; ll.AB.230.244; 11. AB.231.228; ll.AB.231.229; ll.AB.231.230; ll.AB.231.231; ll.AB.231.236; ll.AB.231.237; 11. AB.231.238; ll.AB.231.239; ll.AB.231.154; ll.AB.231.157; ll.AB.231.166; ll.AB.231.169; ll.AB.231.172; ll.AB.231.175; 11. AB .231.240; 11. AB.231.244; ll.AB.236.228; ll.AB.236.229; ll.AB.236.230; ll.AB.236.231; ll.AB.236.236; 11. AB .236.237; ll.AB.236.238; ll.AB.236.239; ll.AB.236.154; ll.AB.236.157; ll.AB.236.166; ll.AB.236.169; ll.AB.236.172; 11. AB .236.175; ll.AB.236.240; ll.AB.236.244; ll.AB.237.228; 11. AB.237.229; ll.AB.237.230; ll.AB.237.231; 11. AB.237.236; ll.AB.237.237; ll.AB.237.238; ll.AB.237.239; ll.AB.237.154; ll.AB.237.157; ll.AB.237.166; ll.AB.237.169; ll.AB.237.172; ll.AB.237.175; 11. AB.237.240; ll.AB.237.244; 11. AB.238.228; ll.AB.238.229; ll.AB.238.230; ll.AB.238.231; ll.AB.238.236; ll.AB.238.237; ll.AB.238.238; ll.AB.238.239; ll.AB.238.154; ll.AB.238.157; ll.AB.238.166; ll.AB.238.169; ll.AB.238.172; ll.AB.238.175; ll.AB.238.240; 11. AB.238.244; ll.AB.239.228; ll.AB.239.229; ll.AB.239.230; ll.AB.239.231; ll.AB.239.236; 11. AB .239.237; ll.AB.239.238; ll.AB.239.239; ll.AB.239.154; ll.AB.239.157; ll.AB.239.166; ll.AB.239.169; 11. AB.239.172; ll.AB.239.175; ll.AB.239.240; 11. AB .239.244; ll.AB.154.228; ll.AB.154.229; ll.AB.154.230; ll.AB.154.231; ll.AB.154.236; ll.AB.154.237; ll.AB.154.238; ll.AB.154.239; ll.AB.154.154; ll.AB.154.157; ll.AB.154.166; ll.AB.154.169; ll.AB.154.172; ll.AB.154.175; ll.AB.154.240; ll.AB.154.244; ll.AB.157.228; ll.AB.157.229; ll.AB.157.230; ll.AB.157.231; ll.AB.157.236; ll.AB.157.237; ll.AB.157.238; ll.AB.157.239; ll.AB.157.154; 11. AB.157.157; ll.AB.157.166; ll.AB.157.169; ll.AB.157.172; ll.AB.157.175; ll.AB.157.240; ll.AB.157.244; ll.AB.166.228; ll.AB.166.229; ll.AB.166.230; ll.AB.166.231; ll.AB.166.236; ll.AB.166.237; ll.AB.166.238; 11. AB.166.239; ll.AB.166.154; ll.AB.166.157; ll.AB.166.166; ll.AB.166.169; ll.AB.166.172; ll.AB.166.175; 11. AB.166.240; ll.AB.166.244; ll.AB.169.228; ll.AB.169.229; ll.AB.169.230; ll.AB.169.231; ll.AB.169.236; ll.AB.169.237; ll.AB.169.238; ll.AB.169.239; ll.AB.169.154; ll.AB.169.157; ll.AB.169.166; ll.AB.169.169; ll.AB.169.172; ll.AB.169.175; ll.AB.169.240; ll.AB.169.244; ll.AB.172.228; ll.AB.172.229; ll.AB.172.230; ll.AB.172.231; ll.AB.172.236; ll.AB.172.237; ll.AB.172.238; ll.AB.172.239; ll.AB.172.154; ll.AB.172.157; ll.AB.172.166; ll.AB.172.169; ll.AB.172.172; ll.AB.172.175; ll.AB.172.240; ll.AB.172.244; 11. AB.175.228; 11. AB.175.229; ll.AB.175.230; ll.AB.175.231; 11. AB.175.236; ll.AB.175.237; 11. AB.175.238; ll.AB.175.239; ll.AB.175.154; ll.AB.175.157; ll.AB.175.166; ll.AB.175.169; ll.AB.175.172; ll.AB.175.175; 11. AB.175.240; 11. AB.175.244; ll.AB.240.228; ll.AB.240.229; ll.AB.240.230; ll.AB.240.231; ll.AB.240.236; ll.AB.240.237; ll.AB.240.238; ll.AB.240.239; ll.AB.240.154; ll.AB.240.157; ll.AB.240.166; ll.AB.240.169; ll.AB.240.172; ll.AB.240.175; ll.AB.240.240; ll.AB.240.244; ll.AB.244.228; ll.AB.244.229; ll.AB.244.230; ll.AB.244.231; ll.AB.244.236; ll.AB.244.237; ll.AB.244.238; ll.AB.244.239; ll.AB.244.154; 11. AB.244.157; ll.AB.244.166; ll.AB.244.169; ll.AB.244.172; ll.AB.244.175; ll.AB.244.240; ll.AB.244.244;

Prodrugs of 11.BI ll.BI.228.228; ll.BI.228.229; ll.BI.228.230; ll.BI.228.231; ll.BI.228.236; ll.BI.228.237; ll.BI.228.238; ll.BI.228.239; ll.BI.228.154; ll.BI.228.157; ll.BI.228.166; ll.BI.228.169; ll.BI.228.172; ll.BI.228.175; ll.BI.228.240; ll.BI.228.244; ll.BI.229.228; ll.BI.229.229; ll.BI.229.230; ll.BI.229.231; ll.BI.229.236; ll.BI.229.237; ll.BI.229.238; ll.BI.229.239; ll.BI.229.154; ll.BI.229.157; ll.BI.229.166; ll.BI.229.169; ll.BI.229.172; ll.BI.229.175; ll.BI.229.240; ll.BI.229.244; ll.BI.230.228; ll.BI.230.229; ll.BI.230.230; ll.BI.230.231; ll.BI.230.236; ll.BI.230.237; ll.BI.230.238; ll.BI.230.239; ll.BI.230.154; ll.BI.230.157; ll.BI.230.166; ll.BI.230.169; ll.BI.230.172; ll.BI.230.175; ll.BI.230.240; ll.BI.230.244; ll.BI.231.228; ll.BI.231.229; ll.BI.231.230; ll.BI.231.231; ll.BI.231.236; ll.BI.231.237; ll.BI.231.238; ll.BI.231.239; ll.BI.231.154; ll.BI.231.157; ll.BI.231.166; ll.BI.231.169; ll.BI.231.172; ll.BI.231.175; ll.BI.231.240; ll.BI.231.244; ll.BI.236.228; ll.BI.236.229; ll.BI.236.230; ll.BI.236.231; ll.BI.236.236; ll.BI.236.237; ll.BI.236.238; ll.BI.236.239; ll.BI.236.154; ll.BI.236.157; ll.BI.236.166; ll.BI.236.169; ll.BI.236.172; ll.BI.236.175; ll.BI.236.240; ll.BI.236.244; ll.BI.237.228; ll.BI.237.229; ll.BI.237.230; ll.BI.237.231; ll.BI.237.236; ll.BI.237.237; ll.BI.237.238; ll.BI.237.239; ll.BI.237.154; ll.BI.237.157; ll.BI.237.166; ll.BI.237.169; ll.BI.237.172; ll.BI.237.175; ll.BI.237.240; ll.BI.237.244; ll.BI.238.228; ll.BI.238.229; ll.BI.238.230; ll.BI.238.231; ll.BI.238.236; ll.BI.238.237; ll.BI.238.238; ll.BI.238.239; ll.BI.238.154; ll.BI.238.157; ll.BI.238.166; ll.BI.238.169; ll.BI.238.172; ll.BI.238.175; ll.BI.238.240; ll.BI.238.244; ll.BI.239.228; ll.BI.239.229; ll.BI.239.230; ll.BI.239.231; ll.BI.239.236; ll.BI.239.237; ll.BI.239.238; ll.BI.239.239; ll.BI.239.154; ll.BI.239.157; ll.BI.239.166; ll.BI.239.169; ll.BI.239.172; ll.BI.239.175; ll.BI.239.240; ll.BI.239.244; ll.BI.154.228; ll.BI.154.229; ll.BI.154.230; ll.BI.154.231; 11. BI.154.236; ll.BI.154.237; ll.BI.154.238; ll.BI.154.239; ll.BI.154.154; 11. BI.154.157; ll.BI.154.166; 11. BI.154.169; ll.BI.154.172; ll.BI.154.175; 11. BI.154.240; ll.BI.154.244; ll.BI.157.228; ll.BI.157.229; ll.BI.157.230; ll.BI.157.231; ll.BI.157.236; ll.BI.157.237; ll.BI.157.238; ll.BI.157.239; ll.BI.157.154; ll.BI.157.157; ll.BI.157.166; ll.BI.157.169; ll.BI.157.172; ll.BI.157.175; ll.BI.157.240; 11. BI.157.244; ll.BI.166.228; ll.BI.166.229; ll.BI.166.230; ll.BI.166.231; 11. BI.166.236; ll.BI.166.237; ll.BI.166.238; ll.BI.166.239; ll.BI.166.154; ll.BI.166.157; ll.BI.166.166; ll.BI.166.169; ll.BI.166.172; ll.BI.166.175; ll.BI.166.240; ll.BI.166.244; ll.BI.169.228; ll.BI.169.229; ll.BI.169.230; ll.BI.169.231; ll.BI.169.236; ll.BI.169.237; ll.BI.169.238; ll.BI.169.239; ll.BI.169.154; ll.BI.169.157; ll.BI.169.166; ll.BI.169.169; ll.BI.169.172; ll.BI.169.175; ll.BI.169.240; ll.BI.169.244; 11. BI.172.228; ll.BI.172.229; 11. BI.172.230; ll.BI.172.231; ll.BI.172.236; 11. BI.172.237; ll.BI.172.238; 11. BI.172.239; ll.BI.172.154; ll.BI.172.157; ll.BI.172.166; ll.BI.172.169; ll.BI.172.172; ll.BI.172.175; ll.BI.172.240; 11. BI.172.244; ll.BI.175.228; ll.BI.175.229; ll.BI.175.230; ll.BI.175.231; ll.BI.175.236; ll.BI.175.237; ll.BI.175.238; ll.BI.175.239; ll.BI.175.154; ll.BI.175.157; ll.BI.175.166; ll.BI.175.169; ll.BI.175.172; ll.BI.175.175; ll.BI.175.240; ll.BI.175.244; ll.BI.240.228; ll.BI.240.229; ll.BI.240.230; ll.BI.240.231; ll.BI.240.236; ll.BI.240.237; 11.BL240.238; ll.BI.240.239; ll.BI.240.154; ll.BI.240.157; ll.BI.240.166; ll.BI.240.169; ll.BI.240.172; ll.BI.240.175; ll.BI.240.240; ll.BI.240.244; ll.BI.244.228; ll.BI.244.229; ll.BI.244.230; ll.BI.244.231; ll.BI.244.236; ll.BI.244.237; ll.BI.244.238; ll.BI.244.239; ll.BI.244.154; ll.BI.244.157; ll.BI.244.166; ll.BI.244.169; ll.BI.244.172; ll.BI.244.175; 11.BL244.240; 11.BL244.244;

Prodrugs of 11.1

11.1.228.228; 11.1.228.229; 11.1.228.230; 11.1.228.231; 11.1.228.236; 11.1.228.237; 11.1.228.238; 11.1.228.239; 11.1.228.154; 11.1.228.157; 11.1.228.166; 11.1.228.169; 11.1.228.172; 11.1.228.175; 11.1.228.240; 11.1.228.244; 11.1.229.228; 11.1.229.229; 11.1.229.230; 11.1.229.231; 11.1.229.236; 11.1.229.237; 11.1.229.238; 11.1.229.239; 11.1.229.154; 11.1.229.157; 11.1.229.166; 11.1.229.169; 11.1.229.172; 11.1.229.175; 11.1.229.240; 11.1.229.244; 11.1.230.228; 11.1.230.229; 11.1.230.230; 11.1.230.231; 11.1.230.236; 11.1.230.237; 11.1.230.238; 11.1.230.239; 11.1.230.154; 11.1.230.157; 11.1.230.166; 11.1.230.169; 11.1.230.172; 11.1.230.175; 11.1.230.240; 11.1.230.244; 11.1.231.228; 11.1.231.229; 11.1.231.230; 11.1.231.231; 11.1.231.236; 11.1.231.237; 11.1.231.238; 11.1.231.239; 11.1.231.154; 11.1.231.157; 11.1.231.166; 11.1.231.169; 11.1.231.172; 11.1.231.175; 11.1.231.240; 11.1.231.244; 11.1.236.228; 11.1.236.229; 11.1.236.230; 11.1.236.231; 11.1.236.236; 11.1.236.237; 11.1.236.238; 11.1.236.239; 11.1.236.154; 11.1.236.157; 11.1.236.166; 11.1.236.169; 11.1.236.172; 11.1.236.175; 11.1.236.240; 11.1.236.244; 11.1.237.228; 11.1.237.229; 11.1.237.230; 11.1.237.231; 11.1.237.236; 11.1.237.237; 11.1.237.238; 11.1.237.239; 11.1237.154; 11.1.237.157; 11.1.237.166; 11.1.237.169; 11.1.237.172; 11.1.237.175; 11.1.237.240; 11.1.237.244; 11.1.238.228; 11.1.238.229; 11.1.238.230; 11.1.238.231; 11.1.238.236; 11.1.238.237; 11.1.238.238; 11.1.238.239; 11.1.238.154; 11.1.238.157; 11.1.238.166; 11.1.238.169; 11.1.238.172; 11.1.238.175; 11.1.238.240; 11.1.238.244; 11.1.239.228; 11.1.239.229; 11.1.239.230; 11.1.239.231; 11.1.239.236; 11.1.239.237; 11.1.239.238; 11.1.239.239; 11.1.239.154; 11.1.239.157; 11.1.239.166; 11.1.239.169; 11.1.239.172; 11.1.239.175; 11.1.239.240; 11.1.239.244; 11.1.154.228; 11.1.154.229; 11.1.154.230; 11.1.154.231; 11.1.154.236; 11.1.154.237; 11.1.154.238; 11.1.154.239; 11.1.154.154; 11.1.154.157; 11.1.154.166; 11.1.154.169; 11.1.154.172; 11.1.154.175; 11.1.154.240; 11.1.154.244; 11.1.157.228; 11.1.157.229; 11.1.157.230; 11.1.157.231; 11.1.157.236; 11.1.157.237; 11.1.157.238; 11.1.157.239; 11.1.157.154; 11.1.157.157; 11.1.157.166; 11.1.157.169; 11.1.157.172; 11.1.157.175; 11.1.157.240; 11.1.157.244; 11.1.166.228; 11.1.166.229; 11.1.166.230; 11.1.166.231; 11.1.166.236; 11.1.166.237; 11.1.166.238; 11.1.166.239; 11.1.166.154; 11.1.166.157; 11.1.166.166; 11.1.166.169; 11.1.166.172; 11.1.166.175; 11.1.166.240; 11.1.166.244; 11.1.169.228; 11.1.169.229; 11.1.169.230; 11.1.169.231; 11.1.169.236; 11.1.169.237; 11.1.169.238; 11.1.169.239; 11.1.169.154; 11.1.169.157; 11.1.169.166; 11.1.169.169; 11.1.169.172; 11.1.169.175; 11.1.169.240; 11.1.169.244; 11.1.172.228; 11.1.172.229; 11.1.172.230; 11.1.172.231; 11.1.172.236; 11.1.172.237; 11.1.172.238; 11.1.172.239; 11.1.172.154; 11.1.172.157; 11.1.172.166; 11.1.172.169; 11.1.172.172; 11.1.172.175; 11.1.172.240; 11.1.172.244; 11.1.175.228; 11.1.175.229; 11.1.175.230; 11.1.175.231; 11.1.175.236; 11.1.175.237; 11.1.175.238; 11.1.175.239; 11.1.175.154; 11.1.175.157; 11.1.175.166; 11.1.175.169; 11.1.175.172; 11.1.175.175; 11.1.175.240; 11.1.175.244; 11.1.240.228; 11.1.240.229; 11.1.240.230; 11.1.240.231; 11.1.240.236; 11.1.240.237; 11.1.240.238; 11.1.240.239; 11.1.240.154; 11.1.240.157; 11.1.240.166; 11.1.240.169; 11.1.240.172; 11.1.240.175; 11.1.240.240; 11.1.240.244; 11.1.244.228; 11.1.244.229; 11.1.244.230; 11.1.244.231; 11.1.244.236; 11.1.244.237; 11.1.244.238; 11.1.244.239; 11.1.244.154; 11.1.244.157; 11.1.244.166; 11.1.244.169; 11.1.244.172; 11.1.244.175; 11.1.244.240; 11.1.244.244;

Prodrugs of 11. T ll.J.228.228; ll.J.228.229; ll.J.228.230; ll.J.228.231; ll.J.228.236; ll.J.228.237; ll.J.228.238; ll.J.228.239; ll.J.228.154; ll.J.228.157; ll.J.228.166; ll.J.228.169; ll.J.228.172; ll.J.228.175; ll.J.228.240; ll.J.228.244; ll.J.229.228; ll.J.229.229; ll.J.229.230; ll.J.229.231; ll.J.229.236; ll.J.229.237; ll.J.229.238; ll.J.229.239; ll.J.229.154; ll.J.229.157; ll.J.229.166; ll.J.229.169; ll.J.229.172; ll.J.229.175; ll.J.229.240; ll.J.229.244; ll.J.230.228; ll.J.230.229; ll.J.230.230; ll.J.230.231; ll.J.230.236; ll.J.230.237; ll.J.230.238; 11J.230.239; ll.J.230.154; ll.J.230.157; ll.J.230.166; ll.J.230.169; ll.J.230.172; ll.J.230.175; ll.J.230.240; ll.J.230.244; ll.J.231.228; ll.J.231.229; ll.J.231.230; ll.J.231.231; ll.J.231.236; ll.J.231.237; ll.J.231.238; ll.J.231.239; ll.J.231.154; ll.J.231.157; ll.J.231.166; ll.J.231.169; ll.J.231.172; ll.J.231.175; ll.J.231.240; ll.J.231.244; ll.J.236.228; ll.J.236.229; ll.J.236.230; ll.J.236.231; ll.J.236.236; ll.J.236.237; ll.J.236.238; ll.J.236.239; ll.J.236.154; ll.J.236.157; 11J.236.166; ll.J.236.169; ll.J.236.172; ϊl.J.236.175; ll.J.236.240; ll.J.236.244; ll.J.237.228; ll.J.237.229; ll.J.237.230; ll.J.237.231; ll.J.237.236; ll.J.237.237; ll.J.237.238; ll.J.237.239; ll.J.237.154; ll.J.237.157; ll.J.237.166; ll.J.237.169; ll.J.237.172; ll.J.237.175; ll.J.237.240; ll.J.237.244; ll.J.238.228; ll.J.238.229; ll.J.238.230; ll.J.238.231; ll.J.238.236; ll.J.238.237; ll.J.238.238; ll.J.238.239; ll.J.238.154; ll.J.238.157; ll.J.238.166; ll.J.238.169; ll.J.238.172; ll.J.238.175; ll.J.238.240; ll.J.238.244; ll.J.239.228; ll.J.239.229; 11J.239.230; ll.J.239.231; ll.J.239.236; ll.J.239.237; ll.J.239.238; ll.J.239.239; ll.J.239.154; ll.J.239.157; ll.J.239.166; ll.J.239.169; ll.J.239.172; ll.J.239.175; ll.J.239.240; ll.J.239.244; ll.J.154.228; ll.J.154.229; ll.J.154.230; ll.J.154.231; ll.J.154.236; ll.J.154.237; ll.J.154.238; ll.J.154.239; ll.J.154.154; ll.J.154.157; ll.J.154.166; ll.J.154.169; ll.J.154.172; ll.J.154.175; ll.J.154.240; ll.J.154.244; ll.J.157.228; ll.J.157.229; ll.J.157.230; ll.J.157.231; ll.J.157.236; ll.J.157.237; ll.J.157.238; ll.J.157.239; ll.J.157.154; ll.J.157.157; ll.J.157.166; ll.J.157.169; ll.J.157.172; ll.J.157.175; ll.J.157.240; ll.J.157.244; ll.J.166.228; ll.J.166.229; ll.J.166.230; ll.J.166.231; ll.J.166.236; ll.J.166.237; ll.J.166.238; ll.J.166.239; ll.J.166.154; ll.J.166.157; ll.J.166.166; ll.J.166.169; ll.J.166.172; ll.J.166.175; 11.J.166.24Q; ll.J.166.244; ll.J.169.228; ll.J.169.229; ll.J.169.230; ll.J.169.231; ll.J.169.236; ll.J.169.237; ll.J.169.238; ll.J.169.239; ll.J.169.154; ll.J.169.157; ll.J.169.166; ll.J.169.169; ll.J.169.172; ll.J.169.175; ll.J.169.240; ll.J.169.244; ll.J.172.228; ll.J.172.229; ll.J.172.230; ll.J.172.231; ll.J.172.236; ll.J.172.237; ll.J.172.238; ll.J.172.239; ll.J.172.154; ll.J.172.157; ll.J.172.166; ll.J.172.169; ll.J.172.172; ll.J.172.175; ll.J.172.240; ll.J.172.244; ll.J.175.228; ll.J.175.229; ll.J.175.230; ll.J.175.231; ll.J.175.236; ll.J.175.237; ll.J.175.238; ll.J.175.239; ll.J.175.154; ll.J.175.157; ll.J.175.166; ll.J.175.169; ll.J.175.172; ll.J.175.175; ll.J.175.240; ll.J.175.244; ll.J.240.228; ll.J.240.229; ll.J.240.230; ll.J.240.231; ll.J.240.236; ll.J.240.237; ll.J.240.238; ll.J.240.239; ll.J.240.154; ll.J.240.157; ll.J.240.166; ll.J.240.169; ll.J.240.172; ll.J.240.175; ll.J.240.240; ll.J.240.244; ll.J.244.228; ll.J.244.229; ll.J.244.230; ll.J.244.231; ll.J.244.236; ll.J.244.237; ll.J.244.238; ll.J.244.239; ll.J.244.154; ll.J.244.157; ll.J.244.166; ll.J.244.169; ll.J.244.172; ll.J.244.175; ll.J.244.240; ll.J.244.244;

Prodrugs of 11. L ll.L.228.228; ll.L.228.229; ll.L.228.230; ll.L.228.231; ll.L.228.236; ll.L.228.237; ll.L.228.238; ll.L.228.239; ll.L.228.154; ll.L.228.157; ll.L.228.166; ll.L.228.169; ll.L.228.172; ll.L.228.175; ll.L.228.240; 11X.228.244; ll.L.229.228; ll.L.229.229; ll.L.229.230; ll.L.229.231; ll.L.229.236; ll.L.229.237; ll.L.229.238; ll.L.229.239; ll.L.229.154; ll.L.229.157; ll.L.229.166; ll.L.229.169; ll.L.229.172; ll.L.229.175; ll.L.229.240; ll.L.229.244; ll.L.230.228; ll.L.230.229; ll.L.230.230; ll.L.230.231; ll.L.230.236; ll.L.230.237; ll.L.230.238; ll.L.230.239; ll.L.230.154; ll.L.230.157; ll.L.230.166; ll.L.230.169; ll.L.230.172; ll.L.230.175; ll.L.230.240; ll.L.230.244; ll.L.231.228; ll.L.231.229; ll.L.231.230; ll.L.231.231; ll.L.231.236; ll.L.231.237; ll.L.231.238; ll.L.231.239; ll.L.231.154; ll.L.231.157; ll.L.231.166; ll.L.231.169; ll.L.231.172; ll.L.231.175; ll.L.231.240; ll.L.231.244; ll.L.236.228; ll.L.236.229; ll.L.236.230; ll.L.236.231; ll.L.236.236; ll.L.236.237; ll.L.236.238; ll.L.236.239; ll.L.236.154; ll.L.236.157; ll.L.236.166; ll.L.236.169; ll.L.236.172; ll.L.236.175; ll.L.236.240; ll.L.236.244; ll.L.237.228; ll.L.237.229; ll.L.237.230; ll.L.237.231; ll.L.237.236; ll.L.237.237; ll.L.237.238; ll.L.237.239; ll.L.237.154; ll.L.237.157; ll.L.237.166; ll.L.237.169; ll.L.237.172; ll.L.237.175; ll.L.237.240; ll.L.237.244; ll.L.238.228; ll.L.238.229; ll.L.238.230; ll.L.238.231; ll.L.238.236; ll.L.238.237; ll.L.238.238; ll.L.238.239; ll.L.238.154; ll.L.238.157; ll.L.238.166; ll.L.238.169; ll.L.238.172; ll.L.238.175; ll.L.238.240; ll.L.238.244; ll.L.239.228; ll.L.239.229; ll.L.239.230; ll.L.239.231; ll.L.239.236; ll.L.239.237; ll.L.239.238; ll.L.239.239; ll.L.239.154; ll.L.239.157; ll.L.239.166; ll.L.239.169; ll.L.239.172; ll.L.239.175; ll.L.239.240; ll.L.239.244; ll.L.154.228; ll.L.154.229; ll.L.154.230; ll.L.154.231; ll.L.154.236; ll.L.154.237; ll.L.154.238; ll.L.154.239; ll.L.154.154; ll.L.154.157; 11X.154.166; ll.L.154.169; ll.L.154.172; ll.L.154.175; ll.L.154.240; ll.L.154.244; ll.L.157.228; ll.L.157.229; ll.L.157.230; ll.L.157.231; ll.L.157.236; ll.L.157.237; ll.L.157.238; ll.L.157.239; ll.L.157.154; ll.L.157.157; ll.L.157.166; ll.L.157.169; ll.L.157.172; ll.L.157.175; ll.L.157.240; ll.L.157.244; ll.L.166.228; ll.L.166.229; ll.L.166.230; ll.L.166.231; ll.L.166.236; ll.L.166.237; ll.L.166.238; ll.L.166.239; ll.L.166.154; ll.L.166.157; ll.L.166.166; ll.L.166.169; ll.L.166.172; ll.L.166.175; ll.L.166.240; ll.L.166.244; ll.L.169.228; ll.L.169.229; ll.L.169.230; ll.L.169.231; ll.L.169.236; ll.L.169.237; ll.L.169.238; ll.L.169.239; ll.L.169.154; ll.L.169.157; ll.L.169.166; ll.L.169.169; ll.L.169.172; ll.L.169.175; ll.L.169.240; ll.L.169.244; ll.L.172.228; ll.L.172.229; ll.L.172.230; ll.L.172.231; ll.L.172.236; ll.L.172.237; ll.L.172.238; ll.L.172.239; ll.L.172.154; ll.L.172.157; ll.L.172.166; ll.L.172.169; ll.L.172.172; ll.L.172.175; ll.L.172.240; ll.L.172.244; ll.L.175.228; ll.L.175.229; ll.L.175.230; ll.L.175.231; ll.L.175.236; ll.L.175.237; ll.L.175.238; ll.L.175.239; ll.L.175.154; ll.L.175.157; ll.L.175.166; ll.L.175.169; ll.L.175.172; ll.L.175.175; 11.L.175.24Q; ll.L.175.244; ll.L.240.228; ll.L.240.229; ll.L.240.230; ll.L.240.231; ll.L.240.236; ll.L.240.237; ll.L.240.238; ll.L.240.239; ll.L.240.154; ll.L.240.157; ll.L.240.166; ll.L.240.169; ll.L.240.172; ll.L.240.175; ll.L.240.240; ll.L.240.244; ll.L.244.228; ll.L.244.229; ll.L.244.230; ll.L.244.231; ll.L.244.236; ll.L.244.237; ll.L.244.238; ll.L.244.239; ll.L.244.154; ll.L.244.157; ll.L.244.166; ll.L.244.169; ll.L.244.172; ll.L.244.175; ll.L.244.240; ll.L.244.244;

Prodrugs of 11.0

11.O.228.228; 11.O.228.229; 11.O.228.230; 11.O.228.231; 11.O.228.236; 11.O.228.237; 11.O.228.238; 11.O.228.239; 11.O.228.154; 11.O.228.157; 11.O.228.166; 11.O.228.169; 11.O.228.172; 11.O.228.175; 11.O.228.240; 11.O.228.244; 11.O.229.228; 11.O.229.229; 11.O.229.230; 11.O.229.231; 11.O.229.236; 11.O.229.237; 11.O.229.238; 11.O.229.239; 11.O.229.154; 11.O.229.157; 11.O.229.166; 11.O.229.169; 11.O.229.172; 11.O.229.175; 11.O.229.240; 11.O.229.244; 11.O.230.228; 11.O.230.229; 11.O.230.230; 11.O.230.231; 11.O.230.236; 11.O.230.237; 11.O.230.238; 11.O.230.239; 11.O.230.154; 11.O.230.157; 11.O.230.166; 11.O.230.169; 11.O.230.172; 11.O.230.175; 11.O.230.240; 11.O.230.244; 11.O.231.228; 11.O.231.229; 11.O.231.230; 11.O.231.231; 11.O.231.236; 11.O.231.237; 11.O.231.238; 11.O.231.239; 11.O.231.154; 11.O.231.157; 11.O.231.166; 11.O.231.169; 11.O.231.172; 11.O.231.175; 11.O.231.240; 11.O.231.244; 11.O.236.228; 11.O.236.229; 11.O.236.230; 11.O.236.231; 11.O.236.236; 11.O.236.237; 11.O.236.238; 11.O.236.239; 11.O.236.154; 11.O.236.157; 11.O.236.166; 11.O.236.169; 11.O.236.172; 11.O.236.175; 11.O.236.240; 11.O.236.244; 11.O.237.228; 11.O.237.229; 11.O.237.230; 11.O.237.231; 11.O.237.236; 11.O.237.237; 11.O.237.238; 11.O.237.239; 11.O.237.154; 11.O.237.157; 11.O.237.166; 11.O.237.169; 11.O.237.172; 11.O.237.175; 11.O.237.240; 11.O.237.244; 11.O.238.228; 11.O.238.229; 11.O.238.230; 11.O.238.231; 11.O.238.236; 11.O.238.237; 11.O.238.238; 11.O.238.239; 11.O.238.154; 11.O.238.157; 11.O.238.166; 11.O.238.169; 11.O.238.172; 11.O.238.175; 11.O.238.240; ll.Q.238.244; ll.Q.239.228; 11.O.239.229; 11.O.239.230; 11.O.239.231; 11.O.239.236; 11.O.239.237; 11.O.239.238; 11.O.239.239; 11.O.239.154; 11.O.239.157; 11.O.239.166; 11.O.239.169; 11.O.239.172; 11.O.239.175; 11.O.239.240; 11.O.239.244; 11.O.154.228; 11.O.154.229; 11.O.154.230; 11.O.154.231; 11.O.154.236; 11.O.154.237; 11.O.154.238; 11.O.154.239; 11.O.154.154; 11.O.154.157; 11.O.154.166; 11.O.154.169; 11.O.154.172; ll.O-154.175; 11.O.154.240; 11.O.154.244; 11.O.157.228; 11.O.157.229; 11.O.157.230; 11.O.157.231; 11.O.157.236; 11.O.157.237; 11.O.157.238; 11.O.157.239; 11.O.157.154; 11.O.157.157; 11.O.157.166; ^' 11.O.157.169; 11.O.157.172; 11.O.157.175; 11.O.157.240; 11.O.157.244; 11.O.166.228; 11.O.166.229; 11.O.166.230; 11.O.166.231; 11.O.166.236; 11.O.166.237; 11.O.166.238; 11.O.166.239; 11.O.166.154; 11.O.166.157; 11.O.166.166; 11.O.166.169; 11.O.166.172; 11.O.166.175; 11.O.166.240; 11.O.166.244; 11.O.169.228; 11.O.169.229; 11.O.169.230; 11.O.169.231; 11.O.169.236; 11.O.169.237; 11.O.169.238; 11.O.169.239; 11.O.169.154; 11.O.169.157; 11.O.169.166; 11.O.169.169; 11.O.169.172; 11.O.169.175; 11.O.169.240; 11.O.169.244; 11.O.172.228; 11.O.172.229; 11.O.172.230; 11.O.172.231; 11.O.172.236; 11.O.172.237; 11.O.172.238; 11.O.172.239; 11.O.172.154; ll.Q.172.157; ll.Q.172.166; 11.O.172.169; 11.O.172.172; 11.O.172.175; 11.O.172.240; 11.O.172.244; 11.O.175.228; 11.O.175.229; 11.O.175.230; 11.O.175.231; 11.O.175.236; 11.O.175.237; 11.O.175.238; 11.O.175.239; 11.O.175.154; 11.O.175.157; 11.O.175.166; 11.O.175.169; 11.O.175.172; 11.O.175.175; 11.O.175.240; 11.O.175.244; 11.O.240.228; 11.O.240.229; 11.O.240.230; 11.O.240.231; 11.O.240.236; 11.O.240.237; 11.O.240.238; 11.O.24Q.239; 11.O.240.154; 11.O.240.157; 11.O.240.166; 11.O.240.169; 11.O.240.172; 11.O.240.175; 11.O.240.240; 11.O.240.244; 11.O.244.228; 11.O.244.229; 11.O.244.230; 11.O.244.231; 11.O.244.236; 11.O.244.237; 11.O.244.238; 11.O.244.239; 11.O.244.154; 11.O.244.157; 11.O.244.166; 11.O.244.169; 11.O.244.172; 11.O.244.175; 11.O.244.240; 11.O.244.244;

Prodrugs of 11. P ll.P.228.228; ll.P.228.229; ll.P.228.230; ll.P.228.231; ll.P.228.236; ll.P.228.237; ll.P.228.238; ll.P.228.239; ll.P.228.154; ll.P.228.157; ll.P.228.166; ll.P.228.169; ll.P.228.172; ll.P.228.175; ll.P.228.240; ll.P.228.244; ll.P.229.228; ll.P.229.229; ll.P.229.230; ll.P.229.231; ll.P.229.236; ll.P.229.237; ll.P.229.238; ll.P.229.239; ll.P.229.154; ll.P.229.157; ll.P.229.166; ll.P.229.169; ll.P.229.172; ll.P.229.175; ll.P.229.240; ll.P.229.244; ll.P.230.228; ll.P.230.229; ll.P.230.230; ll.P.230.231; ll.P.230.236; ll.P.230.237; ll.P.230.238; ll.P.230.239; ll.P.230.154; ll.P.230.157; ll.P.230.166; ll.P.230.169; ll.P.230.172; ll.P.230.175; ll.P.230.240; ll.P.230.244; ll.P.231.228; ll.P.231.229; ll.P.231.230; ll.P.231.231; ll.P.231.236; ll.P.231.237; ll.P.231.238; ll.P.231.239; ll.P.231.154; ll.P.231.157; ll.P.231.166; ll.P.231.169; ll.P.231.172; ll.P.231.175; ll.P.231.240; ll.P.231.244; ll.P.236.228; ll.P.236.229; ll.P.236.230; ll.P.236.231; ll.P.236.236; ll.P.236.237; ll.P.236.238; ll.P.236.239; ll.P.236.154; ll.P.236.157; ll.P.236.166; ll.P.236.169; ll.P.236.172; ll.P.236.175; ll.P.236.240; ll.P.236.244; ll.P.237.228; ll.P.237.229; ll.P.237.230; ll.P.237.231; ll.P.237.236; ll.P.237.237; ll.P.237.238; ll.P.237.239; ll.P.237.154; ll.P.237.157; ll.P.237.166; ll.P.237.169; ll.P.237.172; ll.P.237.175; ll.P.237.240; ll.P.237.244; ll.P.238.228; ll.P.238.229; ll.P.238.230; ll.P.238.231; ll.P.238.236; ll.P.238.237; ll.P.238.238; ll.P.238.239; ll.P.238.154; ll.P.238.157; ll.P.238.166; ll.P.238.169; ll.P.238.172; ll.P.238.175; ll.P.238.240; ll.P.238.244; ll.P.239.228; ll.P.239.229; ll.P.239.230; ll.P.239.231; ll.P.239.236; ll.P.239.237; ll.P.239.238; ll.P.239.239; ll.P.239.154; ll.P.239.157; ll.P.239.166; ll.P.239.169; ll.P.239.172; ll.P.239.175; ll.P.239.240; ll.P.239.244; ll.P.154.228; ll.P.154.229; ll.P.154.230; ll.P.154.231; ll.P.154.236; ll.P.154.237; ll.P.154.238; ll.P.154.239; ll.P.154.154; ll.P.154.157; ll.P.154.166; ll.P.154.169; ll.P.154.172; ll.P.154.175; ll.P.154.240; ll.P.154.244; ll.P.157.228; ll.P.157.229; ll.P.157.230; ll.P.157.231; ll.P.157.236; ll.P.157.237; ll.P.157.238; ll.P.157.239; ll.P.157.154; ll.P.157.157; ll.P.157.166; ll.P.157.169; ll.P.157.172; ll.P.157.175; ll.P.157.240; ll.P.157.244; ll.P.166.228; ll.P.166.229; ll.P.166.230; ll.P.166.231; ll.P.166.236; ll.P.166.237; ll.P.166.238; ll.P.166.239; ll.P.166.154; ll.P.166.157; ll.P.166.166; ll.P.166.169; ll.P.166.172; ll.P.166.175; ll.P.166.240; ll.P.166.244; ll.P.169.228; ll.P.169.229; ll.P.169.230; ll.P.169.231; ll.P.169.236; ll.P.169.237; ll.P.169.238; ll.P.169.239; ll.P.169.154; ll.P.169.157; ll.P.169.166; ll.P.169.169; ll.P.169.172; ll.P.169.175; ll.P.169.240; ll.P.169.244; ll.P.172.228; ll.P.172.229; ll.P.172.230; ll.P.172.231; ll.P.172.236; ll.P.172.237; ll.P.172.238; ll.P.172.239; ll.P.172.154; ll.P.172.157; ll.P.172.166; ll.P.172.169; ll.P.172.172; ll.P.172.175; ll.P.172.240; ll.P.172.244; ll.P.175.228; ll.P.175.229; ll.P.175.230; ll.P.175.231; ll.P.175.236; ll.P.175.237; ll.P.175.238; ll.P.175.239; ll.P.175.154; ll.P.175.157; ll.P.175.166; ll.P.175.169; ll.P.175.172; ll.P.175.175; ll.P.175.240; ll.P.175.244; ll.P.240.228; ll.P.240.229; ll.P.240.230; ll.P.240.231; ll.P.240.236; ll.P.240.237; ll.P.240.238; ll.P.240.239; ll.P.240.154; ll.P.240.157; ll.P.240.166; ll.P.240.169; ll.P.240.172; ll.P.240.175; ll.P.240.240; ll.P.240.244; ll.P.244.228; ll.P.244.229; ll.P.244.230; ll.P.244.231; ll.P.244.236; ll.P.244.237; ll.P.244.238; ll.P.244.239; ll.P.244.154; ll.P.244.157; ll.P.244.166; ll.P.244.169; ll.P.244.172; ll.P.244.175; ll.P.244.240; ll.P.244.244;

Prodrugs of 11.U ll.U.228.228; ll.U.228.229; ll.U.228.230; ll.U.228.231; ll.U.228.236; ll.U.228.237; ll.U.228.238; ll.U.228.239; ll.U.228.154; ll.U.228.157; ll.U.228.166; ll.U.228.169; ll.U.228.172; ll.U.228.175; ll.U.228.240; ll.U.228.244; ll.U.229.228; ll.U.229.229; ll.U.229.230; ll.U.229.231; ll.U.229.236; ll.U.229.237; ll.U.229.238; ll.U.229.239; ll.U.229.154; ll.U.229.157; ll.U.229.166; ll.U.229.169; ll.U.229.172; ll.U.229.175; ll.U.229.240; ll.U.229.244; ll.U.230.228; ll.U.230.229; ll.U.230.230; ll.U.230.231; ll.U.230.236; ll.U.230.237; ll.U.230.238; ll.U.230.239; ll.U.230.154; ll.U.230.157; ll.U.230.166; ll.U.230.169; ll.U.230.172; ll.U.230.175; ll.U.230.240; ll.U.230.244; ll.U.231.228; ll.U.231.229; ll.U.231.230; ll.U.231.231; ll.U.231.236; ll.U.231.237; ll.U.231.238; ll.U.231.239; ll.U.231.154; ll.U.231.157; ll.U.231.166; ll.U.231.169; ll.U.231.172; ll.U.231.175; ll.U.231.240; ll.U.231.244; ll.U.236.228; ll.U.236.229; ll.U.236.230; ll.U.236.231; ll.U.236.236; ll.U.236.237; ll.U.236.238; ll.U.236.239; ll.U.236.154; ll.U.236.157; ll.U.236.166; ll.U.236.169; ll.U.236.172; ll.U.236.175; ll.U.236.240; ll.U.236.244; ll.U.237.228; ll.U.237.229; ll.U.237.230; ll.U.237.231; ll.U.237.236; ll.U.237.237; ll.U.237.238; ll.U.237.239; ll.U.237.154; ll.U.237.157; ll.U.237.166; ll.U.237.169; ll.U.237.172; ll.U.237.175; ll.U.237.240; ll.U.237.244; ll.U.238.228; ll.U.238.229; ll.U.238.230; ll.U.238.231; ll.U.238.236; ll.U.238.237; ll.U.238.238; ll.U.238.239; ll.U.238.154; ll.U.238.157; ll.U.238.166; ll.U.238.169; ll.U.238.172; ll.U.238.175; ll.U.238.240; ll.U.238.244; ll.U.239.228; ll.U.239.229; ll.U.239.230; ll.U.239.231; ll.U.239.236; ll.U.239.237; ll.U.239.238; ll.U.239.239; ll.U.239.154; 11.0.239.157; ll.U.239.166; ll.U.239.169; ll.U.239.172; ll.U.239.175; 11.U.239.24Q; ll.U.239.244; ll.U.154.228; ll.U.154.229; ll.U.154.230; ll.U.154.231; ll.U.154.236; ll.U.154.237; ll.U.154.238; ll.U.154.239; ll.U.154.154; ll.U.154.157; ll.U.154.166; ll.U.154.169; ll.U.154.172; ll.U.154.175; ll.U.154.240; ll.U.154.244; ll.U.157.228; ll.U.157.229; ll.U.157.230; ll.U.157.231; ll.U.157.236; ll.U.157.237; ll.U.157.238; ll.U.157.239; 11. U.157.154; ll.U.157.157; ll.U.157.166; ll.U.157.169; ll.U.157.172; 11. V.157.175; ll.U.157.240; ll.U.157.244; ll.U.166.228; ll.U.166.229; ll.U.166.230; ll.U.166.231; ll.U.166.236; ll.U.166.237; ll.U.166.238; ll.U.166.239; ll.U.166.154; ll.U.166.157; ll.U.166.166; ll.U.166.169; ll.U.166.172; ll.U.166.175; ll.U.166.240; ll.U.166.244; ll.U.169.228; ll.U.169.229; ll.U.169.230; ll.U.169.231; ll.U.169.236; ll.U.169.237; ll.U.169.238; ll.U.169.239; ll.U.169.154; ll.U.169.157; ll.U.169.166; ll.U.169.169; ll.U.169.172; ll.U.169.175; ll.U.169.240; ll.U.169.244; ll.U.172.228; ll.U.172.229; ll.U.172.230; ll.U.172.231; ll.U.172.236; ll.U.172.237; ll.U.172.238; ll.U.172.239; ll.U.172.154; ll.U.172.157; ll.U.172.166; ll.U.172.169; ll.U.172.172; ll.U.172.175; ll.U.172.240; ll.U.172.244; ll.U.175.228; ll.U.175.229; ll.U.175.230; ll.U.175.231; ll.U.175.236; 11. \J.175.237; ll.U.175.238; ll.U.175.239; ll.U.175.154; ll.U.175.157; ll.U.175.166; 11..U..175.169; ll.U.175.172; ll.U.175.175; ll.U.175.240; ll.U.175.244; ll.U.240.228; ll.U.240.229; ll.U.240.230; ll.U.240.231; ll.U.240.236; ll.U.240.237; ll.U.240.238; ll.U.240.239; ll.U.240.154; ll.U.240.157; ll.U.240.166; ll.U.240.169; ll.U.240.172; ll.U.240.175; ll.U.240.240; ll.U.240.244; ll.U.244.228; ll.U.244.229; ll.U.244.230; ll.U.244.231; ll.U.244.236; ll.U.244.237; ll.U.244.238; ll.U.244.239; ll.U.244.154; ll.U.244.157; ll.U.244.166; ll.U.244.169; ll.U.244.172; ll.U.244.175; ll.U.244.240; ll.U.244.244; Prodrugs of ll.CD ll.CD.228.228; ll.CD.228.229; ll.CD.228.230; ll.CD.228.231; ll.CD.228.236; ll.CD.228.237; ll.CD.228.238; ll.CD.228.239; ll.CD.228.154; ll.CD.228.157; ll.CD.228.166; ll.CD.228.169; ll.CD.228.172; ll.CD.228.175; ll.CD.228.240; ll.CD.228.244; ll.CD.229.228; ll.CD.229.229; ll.CD.229.230; ll.CD.229.231; ll.CD.229.236; ll.CD.229.237; ll.CD.229.238; ll.CD.229.239; ll.CD.229.154; ll.CD.229.157; ll.CD.229.166; ll.CD.229.169; ll.CD.229.172; 11. CD.229.175; ll.CD.229.240; ll.CD.229.244; ll.CD.230.228; 11. CD.230.229; ll.CD.230.230; ll.CD.230.231; ll.CD.230.236; ll.CD.230.237; ll.CD.230.238; ll.CD.230.239; ll.CD.230.154; ll.CD.230.157; ll.CD.230.166; ll.CD.230.169; ll.CD.230.172; ll.CD.230.175; ll.CD.230.240; ll.CD.230.244; ll.CD.231.228; ll.CD.231.229; , ll.CD.231.230; ll.CD.231.231; ll.CD.231.236; ll.CD.231.237; ll.CD.231.238; ll.CD.231.239; ll.CD.231.154; ll.CD.231.157; ll.CD.231.166; ll.CD.231.169; ll.CD.231.172; ll.CD.231.175; ll.CD.231.240; ll.CD.231.244; ll.CD.236.228; ll.CD.236.229; ll.CD.236.230; ll.CD.236.231; ll.CD.236.236; ll.CD.236.237; ll.CD.236.238; ll.CD.236.239; ll.CD.236.154; ll.CD.236.157; ll.CD.236.166; ll.CD.236.169; ll.CD.236.172; ll.CD.236-175; ll.CD.236.240; ll.CD.236.244; ll.CD.237.228; 11. CD.237.229; ll.CD.237.230; ll.CD.237.231; ll.CD.237.236; ll.CD.237.237; ll.CD.237.238; ll.CD.237.239; ll.CD.237.154; ll.CD.237.157; ll.CD.237.166; ll.CD.237.169; ll.CD.237.172; ll.CD.237.175; ll.CD.237.240; ll.CD.237.244; ll.CD.238.228; ll.CD.238.229; ll.CD.238.230; ll.CD.238.231; ll.CD.238.236; ll.CD.238.237; ll.CD.238.238; ll.CD.238.239; ll.CD.238.154; ll.CD.238.157; ll.CD.238.166; ll.CD.238.169; ll.CD.238.172; ll.CD.238.175; ll.CD.238.240; ll.CD.238.244; ll.CD.239.228; ll.CD.239.229; ll.CD.239.230; ll.CD.239.231; ll.CD.239.236; ll.CD.239.237; ll.CD.239.238; ll.CD.239.239; ll.CD.239.154; ll.CD.239.157; ll.CD.239.166; ll.CD.239.169; 11. CD.239.172; ll.CD.239.175; ll.CD.239.240; ll.CD.239.244; ll.CD.154.228; ll.CD.154.229; ll.CD.154.230; ll.CD-154.231; ll.CD.154.236; ll.CD.154.237; ll.CD.154.238; ll.CD.154.239; ll.CD.154.154; ll.CD.154.157; ll.CD.154.166; ll.CD.154.169; ll.CD.154.172; ll.CD.154.175; ll.CD.154.240; ll.CD.154.244; ll.CD.157.228; ll.CD.157.229; ll.CD.157.230; ll.CD.157.231; ll.CD.157.236; ll.CD.157.237; ll.CD.157.238; ll.CD.157.239; ll.CD.157.154; ll.CD.157.157; ll.CD.157.166; ll.CD.157.169; 11. CD.157.172; ll.CD.157.175; ll.CD.157.240; ll.CD.157.244; ll.CD.166.228; ll.CD.166.229; ll.CD.166.230; ll.CD.166.231; ll.CD.166.236; ll.CD.166.237; ll.CD.166.238; ll.CD.166.239; ll.CD.166.154; ll.CD.166.157; ll.CD.166.166; ll.CD.166.169; ll.CD.166.172; ll.CD.166.175; ll.CD.166.240; ll.CD.166.244; ll.CD.169.228; ll.CD.169.229; 11.CD.169.23Q; ll.CD.169.231; ll.CD.169.236; ll.CD.169.237; ll.CD.169.238; ll.CD.169.239; ll.CD.169.154; ll.CD.169.157; ll.CD.169.166; ll.CD.169.169; ll.CD.169.172; ll.CD.169.175; ll.CD.169.240; 11. CD.169.244; ll.CD.172.228; ll.CD.172.229; 11. CD.172.230; ll.CD.172.231; ll.CD.172.236; ll.CD.172.237; ll.CD.172.238; ll.CD.172.239; ll.CD.172.154; 11. CD.172.157; ll.CD.172.166; ll.CD.172.169; ll.CD.172.172; ll.CD.172.175; ll.CD.172.240; ll.CD.172.244; ll.CD.175.228; ll.CD.175.229; ll.CD.175.230; ll.CD.175.231; ll.CD.175.236; ll.CD.175.237; ll.CD.175.238; ll.CD.175.239; ll.CD.175.154; ll.CD.175.157; ll.CD.175.166; ll.CD.175.169; ll.CD.175.172; ll.CD.175.175; ll.CD.175.240; ll.CD.175.244; ll.CD.240.228; ll.CD.240.229; ll.CD.240.230; ll.CD.240.231; ll.CD.240.236; ll.CD.240.237; ll.CD.240.238; ll.CD.240.239; 11.CD.24Q.154; ll.CD.240.157; ll.CD.240.166; ll.CD.240.169; ll.CD.240.172; ll.CD.240.175; ll.CD.240.240; ll.CD.240.244; ll.CD.244.228; ll.CD.244.229; ll.CD.244.230; ll.CD.244.231; ll.CD.244.236; ll.CD.244.237; ll.CD.244.238; ll.CD.244.239; ll.CD.244.154; ll.CD.244.157; ll.CD.244.166; ll.CD.244.169; ll.CD.244.172; ll.CD.244.175; ll.CD.244.240; ll.CD.244.244;

Prodrugs of 11.EB ll.EB.228.228; 11. EB.228.229; 11. EB.228.230; ll.EB.228.231; ll.EB.228.236; ll.EB.228.237; ll.EB.228.238; 11. EB .228.239; ll.EB.228.154; ll.EB.228.157; ll.EB.228.166; ll.EB.228.169; ll.EB.228.172; ll.EB.228.175; ll.EB.228.240; ll.EB.228.244; ll.EB.229.228; ll.EB.229.229; ll.EB.229.230; ll.EB.229.231; ll.EB.229.236; ll.EB.229.237; ll.EB.229.238; ll.EB.229.239; ll.EB.229.154; ll.EB.229.157; ll.EB.229.166; ll.EB.229.169; ll.EB.229.172; 11. EB.229.175; ll.EB.229.240; ll.EB.229.244; ll.EB.230.228; ll.EB.230.229; ll.EB.230.230; ll.EB.230.231; ll.EB.230.236; ll.EB.230.237; ll.EB.230.238; ll.EB.230.239; ll.EB.230.154; ll.EB.230.157; ll.EB.230.166; ll.EB.230.169; 11. EB .230.172; ll.EB.230.175; ll.EB.230.240; ll.EB.230.244; ll.EB.231.228; ll.EB.231.229; ll.EB.231.230; ll.EB.231.231; ll.EB.231.236; ll.EB.231.237; ll.EB.231.238; ll.EB.231.239; ll.EB.231.154; ll.EB.231.157; ll.EB.231.166; ll.EB.231.169; ll.EB.231.172; ll.EB.231.175; 11. EB .231.240; 11. EB.231.244; ll.EB.236.228; ll.EB.236.229; ll.EB.236.230; ll.EB.236.231; ll.EB.236.236; ll.EB.236.237; ll.EB.236.238; ll.EB.236.239; ll.EB.236.154; ll.EB.236.157; ll.EB.236.166; ll.EB.236.169; ll.EB.236.172; ll.EB.236.175; ll.EB.236.240; ll.EB.236.244; ll.EB.237.228; 11. EB.237.229; ll.EB.237.230; ll.EB.237.231; ll.EB.237.236; ll.EB.237.237; 11. EB.237.238; ll.EB.237.239; ll.EB.237.154; ll.EB.237.157; ll.EB.237.166; ll.EB.237.169; 11, .EB..237.172; ll.EB.237.175; ll.EB.237.240; ll.EB.237.244; ll.EB.238.228; ll.EB.238.229; ll.EB.238.230; ll.EB.238.231; ll.EB.238.236; ll.EB.238.237; ll.EB.238.238; ll.EB.238.239; ll.EB.238.154; ll.EB.238.157; ll.EB.238.166; 11. EB.238.169; 11. EB .238.172; ll.EB.238.175; ll.EB.238.240; 11. EB.238.244; ll.EB.239.228; 11. EB.239.229; ll.EB.239.230; ll.EB.239.231; 11. EB.239.236; ll.EB.239.237; ll.EB.239.238; ll.EB.239.239; ll.EB.239.154; ll.EB.239.157; ll.EB.239.166; ll.EB.239.169; ll.EB.239.172; ll.EB.239.175; ll.EB.239.240; ll.EB.239.244; ll.EB.154.228; ll.EB.154.229; ll.EB.154.230; ll.EB.154.231; ll.EB.154.236; ll.EB.154.237; ll.EB.154.238; ll.EB.154.239; ll.EB.154.154; ll.EB.154.157; ll.EB.154.166; ll.EB.154.169; ll.EB.154.172; ll.EB.154.175; ll.EB.154.240; ll.EB.154.244; ll.EB.157.228; ll.EB.157.229; ll.EB.157.230; ll.EB.157.231; ll.EB.157.236; ll.EB.157.237; ll.EB.157.238; ll.EB.157.239; ll.EB.157.154; ll.EB.157.157; ll.EB.157.166; ll.EB.157.169; ll.EB.157.172; ll.EB.157.175; ll.EB.157.240; 11. EB.157.244; ll.EB.166.228; ll.EB.166.229; ll.EB.166.230; ll.EB.166.231; ll.EB.166.236; ll.EB.166.237; ll.EB.166.238; ll.EB.166.239; ll.EB.166.154; ll.EB.166.157; ll.EB.166.166; ll.EB.166.169; ll.EB.166.172; ll.EB.166.175; ll.EB.166.240; ll.EB.166.244; 11. EB.169.228; 11. EB.169.229; ll.EB.169.230; ll.EB.169.231; ll.EB.169.236; ll.EB.169.237; ll.EB.169.238; ll.EB.169.239; ll.EB.169.154; ll.EB.169.157; ll.EB.169.166; ll.EB.169.169; ll.EB.169.172; ll.EB.169.175; ll.EB.169.240; ll.EB.169.244; ll.EB.172.228; ll.EB.172.229; ll.EB.172.230; ll.EB.172.231; ll.EB.172.236; 11.EB.172.237} ll.EB.172.238; 11. EB.172.239; ll.EB.172.154; ll.EB.172.157; ll.EB.172.166; ll.EB.172.169; ll.EB.172.172; ll.EB.172.175; ll.EB.172.240; ll.EB.172.244; ll.EB.175.228; 11. EB.175.229; ll.EB.175.230; ll.EB.175.231; ll.EB.175.236; ll.EB.175.237; ll.EB.175.238; ll.EB.175.239; ll.EB.175.154; ll.EB.175.157; ll.EB.175.166; ll.EB.175.169; ll.EB.175.172; ll.EB.175.175; ll.EB.175.240; 11. EB.175.244; ll.EB.240.228; 11.EB.24Q.229; ll.EB.240.230; ll.EB.240.231; ll.EB.240.236; ll.EB.240.237; ll.EB.240.238; ll.EB.240.239; ll.EB.240.154; ll.EB.240.157; ll.EB.240.166; ll.EB.240.169; 11. EB .240.172; ll.EB.240.175; ll.EB.240.240; ll.EB.240.244; ll.EB.244.228; ll.EB.244.229; ll.EB.244.230; ll.EB.244.231; 11. EB.244.236; ll.EB.244.237; ll.EB.244.238; ll.EB.244.239; ll.EB.244.154; ll.EB.244.157; ll.EB.244.166; ll.EB.244.169; ll.EB.244.172; ll.EB.244.175; 11. EB.244.240; ll.EB.244.244;

Prodrugs of 12.B

12.B.228.228; 12.B.228.229; 12.B.228.230; 12.B.228.231; 12.B.228.236; 12.B.228.237; 12.B.228.238; 12.B.228.239; 12.B.228.154; 12.B.228.157; 12.B.228.166; 12.B.228.169; 12.B.228.172; 12.B.228.175; 12.B.228.240; 12.B.228.244; 12.B.229.228; 12.B.229.229; 12.B.229.230; 12.B.229.231; 12.B.229.236; 12.B.229.237; 12.B.229.238; 12.B.229.239; 12.B.229.154; 12.B.229.157; 12.B.229.166; 12.B.229.169; 12.B.229.172; 12.B.229.175; 12.B.229.240; 12.B.229.244; 12.B.230.228; 12.B.230.229; 12.B.230.230; 12.B.230.231; 12.B.230.236; 12.B.230.237; 12.B.230.238; 12.B.230.239; 12.B.230.154; 12.B.230.157; 12.B.230.166; 12.B.230.169; 12.B.23Q.172; 12.B.230.175; 12.B.230.240; 12.B.230.244; 12.B.231.228; 12.B.231.229; 12.B.231.230; 12.B.231.231; 12.B.231.236; 12.B.231.237; 12.B.231.238; 12.B.231.239; 12.B.231.154; 12.B.231.157; 12.B.231.166; 12.B.231.169; 12.B.231.172; 12.B.231.175; 12.B.231.240; 12.B.231.244; 12.B.236.228; 12.B.236.229; 12.B.236.230; 12.B.236.231; 12.B.236.236; 12.B.236.237; 12.B.236.238; 12.B.236.239; 12.B.236.154; 12.B.236.157; 12.B.236.166; 12.B.236.169; 12.B.236.172; 12.B.236.175; 12.B.236.240; 12.B.236.244; 12.B.237.228; 12.B.237.229; 12.B.237.230; 12.B.237.231; 12.B.237.236; 12.B.237.237; 12.B.237.238; 12.B.237.239; 12.B.237.154; 12.B.237.157; 12.B.237.166; 12.B.237.169; 12.B.237.172; 12.B.237.175; 12.B.237.240; 12.B.237.244; 12.B.238.228; 12.B.238.229; 12.B.238.230; 12.B.238.231; 12.B.238.236; 12.B.238.237; 12.B.238.238; 12.B.238.239; 12.B.238.154; 12.B.238.157; 12.B.238.166; 12.B.238.169; 12.B.238.172; 12.B.238.175; 12.B.238.240; 12.B.238.244; 12.B.239.228; 12.B.239.229; 12.B.239.230; 12.B.239.231; 12.B.239.236; 12.B.239.237; 12.B.239.238; 12.B.239.239; 12.B.239.154; 12.B.239.157; 12.B.239.166; 12.B.239.169; 12.B.239.172; 12.B.239.175; 12.B.239.240; 12.B.239.244; 12.B.154.228; 12.B.154.229; 12.B.154.230; 12.B.154.231; 12.B.154.236; 12.B.154.237; 12.B.154.238; 12.B.154.239; 12.B.154.154; 12.B.154.157; 12.B.154.166; 12.B.154.169; 12.B.154.172; 12.B.154.175; 12.B.154.240; 12.B.154.244; 12.B.157.228; 12.B.157.229; 12.B.157.230; 12.B.157.231; 12.B.157.236; 12.B.157.237; 12.B.157.238; 12.B.157.239; 12.B.157.154; 12.B.157.157; 12.B.157.166; 12.B.157.169; 12.B.157.172; 12.B.157.175; 12.B.157.240; 12.B.157.244; 12.B.166.228; 12.B.166.229; 12.B.166.230; 12.B.166.231; 12.B.166.236; 12.B.166.237; 12.B.166.238; 12.B.166.239; 12.B.166.154; 12.B.166.157; 12.B.166.166; 12.B.166.169; 12.B.166.172; 12.B.166.175; 12.B.166.240; 12.B.166.244; 12.B.169.228; 12.B.169.229; 12.B.169.230; 12.B.169.231; 12.B.169.236; 12.B.169.237; 12.B.169.238; 12.B.169.239; 12.B.169.154; 12.B.169.157; 12.B.169.166; 12.B.169.169; 12.B.169.172; 12.B.169.175; 12.B.169.240; 12.B.169.244; 12.B.172.228; 12.B.172.229; 12.B.172.230; 12.B.172.231; 12.B.172.236; 12.B.172.237; 12.B.172.238; 12.B.172.239; 12.B.172.154; 12.B.172.157; 12.B.172.166; 12.B.172.169; 12.B.172.172; 12.B.172.175; 12.B.172.240; 12.B.172.244; 12.B.175.228; 12.B.175.229; 12.B.175.230; 12.B.175.231; 12.B.175.236; 12.B.175.237; 12.B.175.238; 12.B.175.239; 12.B.175.154; 12.B.175.157; 12.B.175.166; 12.B.175.169; 12.B.175.172; 12.B.175.175; 12.B.175.240; 12.B.175.244; 12.B.240.228; 12.B.240.229; 12.B.240.230; 12.B.240.231; 12.B.240.236; 12.B.240.237; 12.B.240.238; 12.B.240.239; 12.B.240.154; 12.B.240.157; 12.B.240.166; 12.B.240.169; 12.B.240.172; 12.B.240.175; 12.B.240.240; 12.B.240.244; 12.B.244.228; 12.B.244.229; 12.B.244.230; 12.B.244.231; 12.B.244.236; 12.B.244.237; 12.B.244.238; 12.B.244.239; 12.B.244.154; 12.B.244.157; 12.B.244.166; 12.B.244.169; 12.B.244.172; 12.B.244.175; 12.B.244.240; 12.B.244.244;

Prodrugs of 12.D

12.D.228.228; 12.D.228.229; 12.D.228.230; 12.D.228.231; 12.D.228.236; 12.D.228.237; 12.D.228.238; 12.D.228.239; 12.D.228.154; 12.D.228.157; 12.D.228.166; 12.D.228.169; 12.D.228.172; 12.P.228.175; 12.D.228.240; 12.D.228.244; 12.D.229.228; 12.D.229.229; 12.D.229.230; 12.D.229.231; 12.D.229.236; 12.D.229.237; 12.D.229.238; 12.D.229.239; 12.D.229.154; 12.D.229.157; 12.D.229.166; 12.D.229.169; 12.D.229.172; 12.D.229.175; 12.D.229.240; 12.D.229.244; 12.D.230.228; 12.D.230.229; 12.D.230.230; 12.D.230.231; 12.D.230.236; 12.D.230.237; 12.D.230.238; 12.D.230.239; 12.D.230.154; 12.D.230.157; 12.D.230.166; 12.D.230.169; 12.D.230.172; 12.D.230.175; 12.D.230.240; 12.D.230.244; 12.D.231.228; 12.D.231.229; 12.D.231.230; 12.D.231.231; 12.D.231.236; 12.D.231.237; 12.D.231.238; 12.D.231.239; 12.D.231.154; 12.D.231.157; 12.D.231.166; 12.D.231.169; 12.D.231.172; 12.D.231.175; 12.D.231.240; 12.D.231.244; 12.D.236.228; 12.D.236.229; 12.D.236.230; 12.D.236.231; 12.D.236.236; 12.D.236.237; 12.D.236.238; 12.D.236.239; 12.D.236.154; 12.D.236.157; 12.D.236.166; 12.D.236.169; 12.D.236.172; 12.D.236.175; 12.D.236.240; 12.D.236.244; 12.D.237.228; 12.D.237.229; 12.D.237.230; 12.D.237.231; 12.D.237.236; 12.D.237.237; 12.D.237.238; 12.D.237.239; 12.D.237.154; 12.D.237.157; 12.D.237.166; 12.D.237.169; 12.D.237.172; 12.D.237.175; 12.D.237.240; 12.D.237.244; 12.D.238.228; 12.D.238.229; 12.D.238.230; 12.D.238.231; 12.D.238.236; 12.D.238.237; 12.D.238.238; 12.D.238.239; 12.D.238.154; 12.D.238.157; 12.D.238.166; 12.D.238.169; 12.D.238.172; 12.D.238.175; 12.D.238.240; 12.D.238.244; 12.D.239.228; 12.D.239.229; 12.D.239.230; 12.D.239.231; 12.D.239.236; 12.D.239.237; 12.D.239.238; 12.D.239.239; 12.D.239.154; 12.D.239.157; 12.D.239.166; 12.D.239.169; 12.D.239.172; 12.D.239.175; 12.D.239.240; 12.D.239.244; 12.D.154.228; 12.D.154.229; 12.D.154.230; 12.D.154.231; 12.D.154.236; 12.D.154.237; 12.D.154.238; 12.D.154.239; 12.D.154.154; 12.D.154.157; 12.D.154.166; 12.D.154.169; 12.D.154.172; 12.D.154.175; 12.D.154.240; 12.D.154.244; 12.D.157.228; 12.D.157.229; 12.D.157.230; 12.D.157.231; 12.D.157.236; 12.D.157.237; 12.D.157.238; 12.D.157.239; 12.D.157.154; 12.D.157.157; 12.D.157.166; 12.D.157.169; 12.D.157.172; 12.D.157.175; 12.D.157.240; 12.D.157.244; 12.D.166.228; 12.D.166.229; 12.D.166.230; 12.D.166.231; 12.D.166.236; 12.D.166.237; 12.D.166.238; 12.D.166.239; 12.D.166.154; 12.D.166.157; 12.D.166.166; 12.D.166.169; 12.D.166.172; 12.D.166.175; 12.D.166.240; 12.D.166.244; 12.D.169.228; 12.D.169.229; 12.D.169.230; 12.D.169.231; 12.D.169.236; 12.D.169.237; 12.D.169.238; 12.D.169.239; 12.D.169.154; 12.D.169.157; 12.D.169.166; 12.D.169.169; 12.D.169.172; 12.D.169.175; 12.D.169.240; 12.D.169.244; 12.D.172.228; 12.D.172.229; 12.D.172.230; 12.D.172.231; 12.D.172.236; 12.D.172.237; 12.D.172.238; 12.D.172.239; 12.D.172.154; 12.D.172.157; 12.D.172.166; 12.D.172.169; 12.D.172.172; 12.D.172.175; 12.D.172.24Q; 12.D.172.244; 12.D.175.228; 12.D.175.229; 12.D.175.230; 12.D.175.231; 12.D.175.236; 12.D.175.237; 12.D.175.238; 12.D.175.239; 12.D.175.154; 12.D.175.157; 12.D.175.166; 12.D.175.169; 12.D.175.172; 12.D.175.175; 12.D.175.240; 12.D.175.244; 12.D.240.228; 12.D.240.229; 12.D.240.230; 12.D.240.231; 12.D.240.236; 12.D.240.237; 12.D.240.238; 12.D.240.239; 12.D.240.154; 12.D.240.157; 12.D.240.166; 12.D.240.169; 12.D.240.172; 12.D.240.175; 12.D.240.240; 12.D.240.244; 12.D.244.228; 12.D.244.229; 12.D.244.230; 12.D.244.231; 12.D:244.236; 12.D.244.237; 12.D.244.238; 12.D.244.239; 12.D.244.154; 12.D.244.157; 12.D.244.166; 12.D.244.169; 12.D.244.172; 12.D.244.175; 12.D.244.240; 12.D.244.244;

Prodrugs of 12.AB

12.AB.228.228; 12.AB.228.229; 12.AB.228.230; 12.AB.228.231; 12.AB.228.236; 12.AB.228.237; 12.AB.228.238; 12.AB.228.239; 12.AB.228.154; 12.AB.228.157; 12.AB.228.166; 12.AB.228.169; 12.AB.228.172; 12.AB.228.175; 12.AB.228.240; 12.AB.228.244; 12.AB.229.228; 12.AB.229.229; 12.AB.229.230; 12.AB.229.231; 12.AB.229.236; 12.AB.229.237; 12.AB.229.238; 12.AB.229.239; 12.AB.229.154; 12.AB.229.157; 12.AB.229.166; 12.AB.229.169; 12.AB.229.172; 12.AB.229.175; 12.AB.229.240; 12.AB.229.244; 12.AB.230.228; 12.AB.230.229; 12.AB.230.230; 12.AB.230.231; 12.AB.230.236; 12.AB.230.237; 12.AB.230.238; 12. AB.230.239; 12.AB.230.154; 12.AB.230.157; 12.AB.230.166; 12.AB.230.169; 12.AB.230.172; 12.AB.230.175; 12.AB.230.240; 12.AB.230.244; 12.AB.231.228; 12.AB.231.229; 12.AB.231.230; 12.AB.231.231; 12.AB.231.236; 12.AB.231.237; 12.AB.231.238; 12.AB.231.239; 12.AB.231.154; 12.AB.231.157; 12.AB.231.166; 12.AB.231.169; 12.AB.231.172; 12.AB.231.175; 12.AB.231.240; 12.AB.231.244; 12.AB.236.228; 12.AB.236.229; 12.AB.236.230; 12.AB.236.231; 12.AB.236.236; 12.AB.236.237; 12.AB.236.238; 12.AB.236.239; 12.AB.236.154; 12.AB.236.157; 12.AB.236.166; 12.AB.236.169; 12.AB.236.172; 12.AB.236.175; 12.AB.236.240; 12.AB.236.244; 12.AB.237.228; 12.AB.237.229; 12.AB.237.230; 12.AB.237.231; 12.AB.237.236; 12.AB.237.237; 12.AB.237.238; 12.AB.237.239; 12.AB.237.154; 12.AB.237.157; 12.AB.237.166; 12.AB.237.169; 12.AB.237.172; 12.AB.237.175; 12.AB.237.240; 12.AB.237.244; 12.AB.238.228; 12.AB.238.229; 12.AB.238.230; 12.AB.238.231; 12.AB.238.236; 12.AB.238.237; 12.AB.238.238; 12.AB.238.239; 12.AB.238.154; 12.AB.238.157; 12.AB.238.166; 12.AB.238.169; 12.AB.238.172; 12.AB.238.175; 12.AB.238.240; 12.AB.238.244; 12.AB.239.228; 12.AB.239.229; 12.AB.239.230; 12.AB.239.231; 12.AB.239.236; 12.AB.239.237; 12.AB.239.238; 12.AB.239.239; 12.AB.239.154; 12.AB.239.157; 12.AB.239.166; 12.AB.239.169; 12.AB.239.172; 12.AB.239.175; 12.AB.239.240; 12.AB.239.244; 12.AB.154.228; 12.AB.154.229; 12.AB.154.230; 12.AB.154.231; 12.AB.154.236; 12.AB.154.237; 12.AB.154.238; 12.AB.154.239; 12.AB.154.154; 12.AB.154.157; 12.AB.154.166; 12.AB.154.169; 12.AB.154.172; 12.AB.154.175; 12.AB.154.240; 12.AB.154.244; 12.AB.157.228; 12.AB.157.229; 12.AB.157.230; 12.AB.157.231; 12.AB.157.236; 12.AB.157.237; 12.AB.157.238; 12.AB.157.239; 12.AB.157.154; 12.AB.157.157; 12.AB.157.166; 12.AB.157.169; 12.AB.157.172; 12.AB.157.175; 12.AB.157.240; 12.AB.157.244; 12.AB.166.228; 12.AB.166.229; 12.AB.166.230; 12.AB.166.231; 12.AB.166.236; 12.AB.166.237; 12.AB.166.238; 12.AB.166.239; 12.AB.166.154; 12.AB.166.157; 12.AB.166.166; 12.AB.166.169; 12.AB.166.172; 12.AB.166.175; 12.AB.166.24Q; 12.AB.166.244; 12. AB.169.228; 12.AB.169.229; 12.AB.169.230; 12.AB.169.231; 12.AB.169.236; 12.AB.169.237; 12.AB.169.238; 12.AB.169.239; 12.AB.169.154; 12.AB.169.157; 12.AB.169.166; 12.AB.169.169; 12.AB.169.172; 12.AB.169.175; 12.AB.169.240; 12. AB.169.244; 12.AB.172.228; 12.AB.172.229; 12.AB.172.230; 12.AB.172.231; 12.AB.172.236; 12.AB.172.237; 12.AB.172.238; 12.AB.172.239; 12.AB.172.154; 12.AB.172.157; 12.AB.172.166; 12.AB.172.169; 12.AB.172.172; 12.AB.172.175; 12.AB.172.240; 12.AB.172.244; 12.AB.175.228; 12.AB.175.229; 12.AB.175.230; 12.AB.175.231; 12. AB.175.236; 12.AB.175.237; 12.AB.175.238; 12.AB.175.239; 12.AB.175.154; 12.AB.175.157; 12.AB.175.166; 12.AB.175.169; 12.AB.175.172; 12.AB.175.175; 12.AB.175.240; 12.AB.175.244; 12.AB.240.228; 12.AB.240.229; 12.AB.240.230; 12.AB.240.231; 12.AB.24Q.236; 12.AB.240.237; 12.AB.240.238; 12.AB.240.239; 12.AB.240.154; 12.AB.240.157; 12.AB.240.166; 12.AB.240.169; 12.AB.240.172; 12.AB.240.175; 12.AB.240.240; 12.AB.240.244; 12.AB.244.228; 12.AB.244.229; 12.AB.244.230; 12.AB.244.231; 12.AB.244.236; 12.AB.244.237; 12.AB.244.238; 12.AB.244.239; 12.AB.244.154; 12.AB.244.157; 12.AB.244.166; 12.AB.244.169; 12.AB.244.172; 12.AB.244.175; 12.AB.244.240; 12.AB.244.244;

Prodrugs of 12.BI

12.BI.228.228; 12.BI.228.229; 12.BI.228.230; 12.BI.228.231; 12.BI.228.236; 12.BI.228.237; 12.BI.228.238; 12.BI.228.239; 12.BI.228.154; 12.BI.228.157; 12.BI.228.166; 12.BI.228.169; 12.BI.228.172; 12.BI.228.175; 12.BI.228.240; 12.BI.228.244; 12.BI.229.228; 12.BI.229.229; 12.BI.229.230; 12.BI.229.231; 12.BI.229.236; 12.BI.229.237; 12.BI.229.238; 12.BI.229.239; 12.BI.229.154; 12.BI.229.157; 12.BI.229.166; 12.BI.229.169; 12.BI.229.172; 12.BI.229.175; 12.BI.229.240; 12.BI.229.244; 12.BI.230.228; 12.BI.230.229; 12.BI.230.230; 12.BI.230.231; 12.BI.230.236; 12.BI.230.237; 12.BI.230.238; 12.BI.230.239; 12.BI.230.154; 12.BI.230.157; 12.BI.230.166; 12.BL230.169; 12.BI.230.172; 12.BI.230.175; 12.BI.230.240; 12.BI.230.244; 12.BI.231.228; 12.BI.231.229; 12.BI.231.230; 12.BI.231.231; 12.BI.231.236; 12.BI.231.237; 12.BI.231.238; 12.BI.231.239; 12.BI.231.154; 12.BI.231.157; 12.BI.231.166; 12.BI.231.169; 12.BI.231.172; 12.BI.231.175; 12.BI.231.240; 12.BI.231.244; 12.BI.236.228; 12.BI.236.229; 12.BI.236.230; 12.BI.236.231; 12.BI.236.236; 12.BI.236.237; 12.BI.236.238; 12.BI.236.239; 12.BI.236.154; 12.BI.236.157; 12.BI.236.166; 12.BI.236.169; 12.BI.236.172; 12.BI.236.175; 12.BI.236.240; 12.BI.236.244; 12.BI.237.228; 12.BI.237.229; 12.BI.237.230; 12.BI.237.231; 12.BI.237.236; 12.BI.237.237; 12.BI.237.238; 12.BI.237.239; 12.BI.237.154; 12.BI.237.157; 12.BI.237.166; 12.BI.237.169; 12.BI.237.172; 12.BI.237.175; 12.BI.237.240; 12.BI.237.244; 12.BI.238.228; 12.BI.238.229; 12.BI.238.230; 12.BI.238.231; 12.BI.238.236; 12.BI.238.237; 12.BI.238.238; 12.BI.238.239; 12.BI.238.154; 12.BI.238.157; 12.BI.238.166; 12.BI.238.169; 12.BI.238.172; 12.BI.238.175; 12.BI.238.240; 12.BI.238.244; 12.BI.239.228; 12.BI.239.229; 12.BI.239.230; 12.BI.239.231; 12.BI.239.236; 12.BI.239.237; 12.BL239.238; 12.BI.239.239; 12.BI.239.154; 12.BI.239.157; 12.BI.239.166; 12.BL239.169; 12.BI.239.172; 12.BI.239.175; 12.BI.239.240; 12.BI.239.244; 12.BI.154.228; 12.BI.154.229; 12.BI.154.230; 12.BI.154.231; 12.BI.154.236; 12.BI.154.237; 12.BI.154.238; 12.BI.154.239; 12.BI.154.154; 12.BI.154.157; 12.BI.154.166; 12.BI.154.169; 12.BI.154.172; 12.BI.154.175; 12.BI.154.240; 12.BI.154.244; 12.BI.157.228; 12.BI.157.229; 12.BI.157.230; 12.BI.157.231; 12.BI.157.236; 12.BI.157.237; 12.BI.157.238; 12.BI.157.239; 12.BI.157.154; 12.BI.157.157; 12.BI.157.166; 12.BI.157.169; 12.BI.157.172; 12.BI.157.175; 12.BI.157.240; 12.BI.157.244; 12.BI.166.228; 12.BI.166.229; 12.BI.166.230; 12.BI.166.231; 12.BI.166.236; 12.BI.166.237; 12.BI.166.238; 12.BI.166.239; 12.BI.166.154; 12.BI.166.157; 12.BI.166.166; 12.BI.166.169; 12.BI.166.172; 12.BI.166.175; 12.BI.166.240; 12.BI.166.244; 12.BI.169.228; 12.BI.169.229; 12.BI.169.230; 12.BI.169.231; 12.BI.169.236; 12.BI.169.237; 12.BI.169.238; 12.BI.169.239; 12.BI.169.154; 12.BI.169.157; 12.BI.169.166; 12.BI.169.169; 12.BI.169.172; 12.BI.169.175; 12.BI.169.240; 12.BI.169.244; 12.BI.172.228; 12.BI.172.229; 12.BI.172.230; 12.BI.172.231; 12.BL172.236; 12.BI.172.237; 12.BI.172.238; 12.BI.172.239; 12.BI.172.154; 12.BI.172.157; 12.BI.172.166; 12.BI.172.169; 12.BI.172.172; 12.BI.172.175; 12.BI.172.240; 12.BI.172.244; 12.BI.175.228; 12.BI.175.229; 12.BI.175.230; 12.BI.175.231; 12.BI.175.236; 12.BI.175.237; 12.BI.175.238; 12.BI.175.239; 12.BI.175.154; 12.BI.175.157; 12.BI.175.166; 12.BI.175.169; 12.BI.175.172; 12.BI.175.175; 12.BI.175.240; 12.BI.175.244; 12.BI.240.228; 12.BI.240.229; 12.BL240.230; 12.BI.24Q.231; 12.BI.240.236; 12.BI.240.237; 12.BI.240.238; 12.BI.240.239; 12.BI.240.154; 12.BL240.157; 12.BI.240.166; 12.BI.240.169; 12.BI.240.172; 12.BI.240.175; 12.BI.240.240; 12.BI.240.244; 12.BI.244.228; 12.BI.244.229; 12.BI.244.230; 12.BI.244.231; 12.BI.244.236; 12.BI.244.237; 12.BI.244.238; 12.BI.244.239; 12.BI.244.154; 12.BI.244.157; 12.BI.244.166; 12.BI.244.169; 12.BI.244.172; 12.BI.244.175; 12.BI.244.240; 12.BI.244.244;

Prodrugs of 12.1

12.1.228.228; 12.1.228.229; 12.1.228.230; 12.1.228.231; 12.1.228.236; 12.1.228.237; 12.1.228.238; 12.1.228.239; 12.1.228.154; 12.1.228.157; 12.1.228.166; 12.1.228.169; 12.1.228.172; 12.1.228.175; 12.1.228.240; 12.1.228.244; 12.1.229.228; 12.1.229.229; 12.1.229.230; 12.1.229.231; 12.1.229.236; 12.1.229.237; 12.1.229.238; 12.1.229.239; 12.1.229.154; 12.1.229.157; 12.1.229.166; 12.1.229.169; 12.1.229.172; 12.1.229.175; 12.1.229.240; 12.1.229.244; 12.1.230.228; 12.1.230.229; 12.1.230.230; 12.1.230.231; 12.1.230.236; 12.1.230.237; 12.1.230.238; 12.1.230.239; 12.1.230.154; 12.1.230.157; 12.1.230.166; 12.1.230.169; 12.1.230.172; 12.1.230.175; 12.1.230.240; 12.1.230.244; 12.1.231.228; 12.1.231.229; 12.1.231.230; 12.1.231.231; 12.1.231.236; 12.1.231.237; 12.1.231.238; 12.1.231.239; 12.1.231.154; 12.1.231.157; 12.1.231.166; 12.1.231.169; 12.1.231.172; 12.1.231.175; 12.1.231.240; 12.1.231.244; 12.1.236.228; 12.1.236.229; 12.1.236.230; 12.1.236.231; 12.1.236.236; 12.1.236.237; 12.1.236.238; 12.1.236.239; 12.1.236.154; 12.1.236.157; 12.1.236.166; 12.1.236.169; 12.1.236.172; 12.1.236.175; 12.1.236.240; 12.1.236.244; 12.1.237.228; 12.1.237.229; 12.1.237.230; 12.1.237.231; 12.1.237.236; 12.1.237.237; 12.1.237.238; 12.1.237.239; 12.1.237.154; 12.1.237.157; 12.1.237.166; 12.1.237.169; 12.1.237.172; 12.1.237.175; 12.1.237.240; 12.1.237.244; 12.1.238.228; 12.1.238.229; 12.1.238.230; 12.1.238.231; 12.1.238.236; 12.1.238.237; 12.1.238.238; 12.1238.239; 12.1.238.154; 12.1.238.157; 12.1.238.166; 12.1.238.169; 12.1.238.172; 12.1.238.175; 12.1.238.240; 12.1.238.244; 12.1.239.228; 12.1.239.229; 12.1.239.230; 12.1.239.231; 12.1.239.236; 12.1.239.237; 12.1.239.238; 12.1.239.239; 12.1.239.154; 12.1.239.157; 12.1.239.166; 12.1.239.169; 12.1.239.172; 12.1.239.175; 12.1.239.240; 12.1.239.244; 12.1.154.228; 12.1.154.229; 12.1.154.230; 12.1.154.231; 12.1.154.236; 12.1.154.237; 12.1.154.238; 12.1.154.239; 12.1.154.154; 12.1.154.157; 12.1.154.166; 12.1.154.169; 12.1.154.172; 12.1.154.175; 12.1.154.240; 12.1.154.244; 12.1.157.228; 12.1.157.229; 12.1.157.230; 12.1.157.231; 12.1.157.236; 12.1.157.237; 12.1.157.238; 12.1.157.239; 12.1.157.154; 12.1.157.157; 12.1.157.166; 12.1.157.169; 12.1.157.172; 12.1.157.175; 12.1.157.240; 12.1.157.244; 12.1.166.228; 12.1.166.229; 12.1.166.230; 12.1.166.231; 12.1.166.236; 12.1.166.237; 12.1.166.238; 12.1.166.239; 12.1.166.154; 12.1.166.157; 12.1.166.166; 12.1.166.169; 12.1.166.172; 12.1.166.175; 12.1.166.240; 12.1.166.244; 12.1.169.228; 12.1.169.229; 12.1.169.230; 12.1.169.231; 12.1.169.236; 12.1.169.237; 12.1.169.238; 12.1.169.239; 12.1.169.154; 12.1.169.157; 12.1.169.166; 12.1.169.169; 12.1.169.172; 12.1.169.175; 12.1.169.240; 12.1.169.244; 12.1.172.228; 12.1.172.229; 12.1.172.230; 12.1.172.231; 12.1.172.236; 12.1.172.237; 12.1.172.238; 12.1.172.239; 12.1.172.154; 12.1.172.157; 12.1.172.166; 12.1.172.169; 12.1.172.172; 12.1.172.175; 12.1.172.240; 12.1.172.244; 12.1.175.228; 12.1.175.229; 12.1.175.230; 12.1.175.231; 12.1.175.236; 12.1.175.237; 12.1.175.238; 12.1.175.239; 12.1.175.154; 12.1.175.157; 12.1.175.166; 12.1.175.169; 12.1.175.172; 12.1.175.175; 12.1.175.240; 12.1.175.244; 12.1.240.228; 12.1.240.229; 12.1.240.230; 12.1.240.231; 12.1.240.236; 12.1.240.237; 12.1.240.238; 12.1.240.239; 12.1.240.154; 12.1.240.157; 12.1.240.166; 12.1.240.169; 12.1.240.172; 12.1.240.175; 12.1.240.240; 12.1.240.244; 12.1.244.228; 12.1.244.229; 12.1.244.230; 12.1.244.231; 12.1.244.236; 12.1.244.237; 12.1.244.238; 12.1.244.239; 12.1.244.154; 12.1.244.157; 12.1.244.166; 12.1.244.169; 12.1.244.172; 12.1.244.175; 12.1.244.240; 12.1.244.244;

Prodrugs of 12.T

12.J.228.228; 12.J.228.229; 12.J.228.230; 12J.228.231; 12.J.228.236; 12.J.228.237; 12.J.228.238; 12.J.228.239; 12.J.228.154; 12.J.228.157; 12.J.228.166; 12.J.228.169; 12.J.228.172; 12.J.228.175; 12.J.228.240; 12.J.228.244; 12.J.229.228; 12.J.229.229; 12.J.229.230; 12J.229.231; 12.J.229.236; 12.J.229.237; 12.J.229.238; 12.J.229.239; 12.J.229.154; 12.J.229.157; 12.J.229.166; 12.J.229.169; 12.J.229.172; 12.J.229.175; 12.J.229.240; 12.J.229.244; 12.J.230.228; 12.J.230.229; 12.J.230.230; 12 J.230.231; 12.J.230.236; 12.J.230.237; 12.J.230.238; 12.J.230.239; 12.J.230.154; 12.J.230.157; 12.J.230.166; 12.J.230.169; 12.J.230.172; 12.J.230.175; 12.J.230.240; 12.J.230.244; 12.J.231.228; 12.J.231.229; 12.J.231.230; 12J.231.231; 12J.231.236; 12J.231.237; 12J.231.238; 12J.231.239; 12J.231.154; 12J.231.157; 12J.231.166; 12J.231.169; 12J.231.172; 12J.231.175; 12J.231.240; 12J.231.244; 12J.236.228; 12J.236.229; 12J.236.230; 12 J.236.231; 12.J.236.236; 12J.236.237; 12J.236.238; 12J.236.239; 12J.236.154; 12.J.236.157; 12J.236.166; 12.J.236.169; 12J.236.172; 12J.236.175; 12J.236.240; 12J.236.244; 12J.237.228; 12J.237.229; 12J.237.230; 12J.237.231; 12J.237.236; 12J.237.237; 12J.237.238; 12J.237.239; 12J.237.154; 12J.237.157; 12J.237.166; 12J.237.169; 12J.237.172; 12J.237.175; 12.J.237.240; 12J.237.244; 12J.238.228; 12J.238.229; 12.J.238.230; 12J.238.231; 12J.238.236; 12J.238.237; 12J.238.238; 12J.238.239; 12J.238.154; 12J.238.157; 12J.238.166; 12J.238.169; 12J.238.172; 12J.238.175; 12J.238.240; 12J.238.244; 12J.239.228; 12J.239.229; 12J.239.230; 12J.239.231; 12J.239.236; 12J.239.237; 12J.239.238; 12J.239.239; 12J.239.154; 12J.239.157; 12J.239.166; 12.J.239.169; 12J.239.172; 12J.239.175; 12J.239.240; 12.J.239.244; 12J.154.228; 12J.154.229; 12J.154.230; 12J.154.231; 12J.154.236; 12J.154.237; 12J.154.238; 12J.154.239; 12J.154.154; 12J.154.157; 12J.154.166; 12J.154.169; 12J.154.172; 12J.154.175; 12J.154.240; 12J.154.244; 12J.157.228; 12J.157.229; 12J.157.230; 12J.157.231; 12J.157.236; 12J.157.237; 12.J.157.238; 12J.157.239; 12J.157.154; 12J.157.157; 12J.157.166; 12J.157.169; 12J.157.172; 12J.157.175; 12.J.157.240; 12J.157.244; 12.J.166.228; 12J.166.229; 12.J.166.230; 12J.166.231; 12J.166.236; 12J.166.237; 12J.166.238; 12J.166.239; 12J.166.154; 12J.166.157; 12J.166.166; 12J.166.169; 12J.166.172; 12J.166.175; 12.J.166.240; 12J.166.244; 12J.169.228; 12J.169.229; 12J.169.230; 12J.169.231; 12J.169.236; 12J.169.237; 12J.169.238; 12J.169.239; 12J.169.154; 12J.169.157; 12J.169.166; 12J.169.169; 12J.169.172; 12J.169.175; 12J.169.240; 12J.169.244; 12J.172.228; 12J.172.229; 12J.172.230; 12J.172.231; 12J.172.236; 12J.172.237; 12J.172.238; 12J.172.239; 12J.172.154; 12J.172.157; 12J.172.166; 12J.172.169; 12J.172.172; 12J.172.175; 12J.172.240; 12J.172.244; 12J.175.228; 12J.175.229; 12J.175.230; 12J.175.231; 12J.175.236; 12J.175.237; 12J.175.238; 12J.175.239; 12J.175.154; 12J.175.157; 12J.175.166; 12J.175.169; 12J.175.172; 12J.175.175; 12 J.175.240; 12 J.175.244; 12J.240.228; 12J.240.229; 12J.240.230; 12J.240.231; 12 J.240.236; 12J.240.237; 12.J.240.238; 12J.240.239; 12J.240.154; 12J.240.157; 12J.240.166; 12J.240.169; 12J.240.172; 12J.240.175; 12J.240.240; 12J.240.244; 12.J.244.228; 12J.244.229; 12J.244.230; 12J.244.231; 12J.244.236; 12J.244.237; 12J.244.238; 12 J.244.239; 12.J.244.154; 12.J.244.157; 12J.244.166; 12J.244.169; 12J.244.172; 12J.244.175; 12J.244.240; 12J.244.244;

Prodrugs of 12.L

12.L.228.228; 12.L.228.229; 12.L.228.230; 12.L.228.231; 12.L.228.236; 12.L.228.237; 12.L.228.238; 12.L.228.239; 12.L.228.154; 12.L.228.157; 12.L.228.166; 12.L.228.169; 12.L.228.172; 12.L.228.175; 12.L.228.240; 12.L.228.244; 12.L.229.228; 12.L.229.229; 12.L.229.230; 12.L.229.231; 12.L.229.236; 12.L.229.237; 12.L.229.238; 12.L.229.239; 12.L.229.154; 12.L.229.157; 12.L.229.166; 12.L.229.169; 12.L.229.172; 12.L.229.175; 12.L.229.240; 12.L.229.244; 12.L.230.228; 12.L.230.229; 12.L.230.230; 12.L.230.231; 12.L.230.236; 12.L.230.237; 12.L.230.238; 12.L.230.239; 12.L.230.154; 12.L.230.157; 12.L.230.166; 12.L.230.169; 12.L.230.172; 12.L.230.175; 12.L.230.240; 12.L.230.244; 12.L.231.228; 12.L.231.229; 12.L.231.230; 12.L.231.231; 12.L.231.236; 12.L.231.237; 12.L.231.238; 12.L.231.239; 12.L.231.154; 12.L.231.157; 12.L.231.166; 12.L.231.169; 12.L.231.172; 12.L.231.175; 12.L.231.240; 12.L.231.244; 12.L.236.228; 12.L.236.229; 12.L.236.230; 12.L.236.231; 12.L.236.236; 12.L.236.237; 12.L.236.238; 12.L.236.239; 12.L.236.154; 12.L.236.157; 12.L.236.166; 12.L.236.169; 12.L.236.172; 12.L.236.175; 12.L.236.240; 12.L.236.244; 12.L.237.228; 12.L.237.229; 12.L.237.230; 12.L.237.231; 12.L.237.236; 12.L.237.237; 12.L.237.238; 12.L.237.239; 12.L.237.154; 12.L.237.157; 12.L.237.166; 12.L.237.169; 12.L.237.172; 12.L.237.175; 12.L.237.240; 12.L.237.244; 12.L.238.228; 12.L.238.229; 12.L.238.23Q; 12.L.238.231; 12.L.238.236; 12.L.238.237; 12.L.238.238; 12.L.238.239; 12.L.238.154; 12.L.238.157; 12.L.238.166; 12.L.238.169; 12.L.238.172; 12.L.238.175; 12.L.238.240; 12.L.238.244; 12.L.239.228; 12.L.239.229; 12.L.239.230; 12.L.239.231; 12.L.239.236; 12.L.239.237; 12.L.239.238; 12.L.239.239; 12.L.239.154; 12.L.239.157; 12.L.239.166; 12.L.239.169; 12.L.239.172; 12.L.239.175; 12.L.239.240; 12.L.239.244; 12.L.154.228; 12.L.154.229; 12.L.154.230; 12.L.154.231; 12.L.154.236; 12.L.154.237; 12.L.154.238; 12.L.154.239; 12.L.154.154; 12.L.154.157; 12.L.154.166; 12.L.154.169; 12.L.154.172; 12.L.154.175; 12.L.154.240; 12.L.154.244; 12.L.157.228; 12.L.157.229; 12.L.157.230; 12.L.157.231; 12.L.157.236; 12.L.157.237; 12.L.157.238; 12.L.157.239; 12.L.157.154; 12.L.157.157; 12.L.157.166; 12.L.157.169; 12.L.157.172; 12.L.157.175; 12.L.157.240; 12.L.157.244; 12.L.166.228; 12.L.166.229; 12.L.166.230; 12.L.166.231; 12.L.166.236; 12.L.166.237; 12.L.166.238; 12.L.166.239; 12.L.166.154; 12.L.166.157; 12.L.166.166; 12X.166.169; 12.L.166.172; 12.L.166.175; 12.L.166.24Q; 12X.166.244; 12X.169.228; 12X.169.229; 12.L.169.230; 12X.169.231; 12X.169.236; 12X.169.237; 12X.169.238; 12X.169.239; 12X.169.154; 12X.169.157; 12X.169.166; 12X.169.169; 12X.169.172; 12X.169.175; 12.L.169.240; 12X.169.244; 12X.172.228; 12X.172.229; 12X.172.230; 12X.172.231; 12X.172.236; 12X.172.237; 12X.172.238; 12X.172.239; 12X.172.154; 12X.172.157; 12X.172.166; 12X.172.169; 12X.172.172; 12X.172.175; 12X.172.240; 12X.172.244; 12X175.228; 12X.175.229; 12X.175.230; 12X.175.231; 12X.175.236; 12X.175.237; 12X.175.238; 12X.175.239; 12X.175.154; 12X.175.157; 12X.175.166; 12X.175.169; 12X.175.172; 12X.175.175; 12X.175.240; 12X.175.244; 12X.240.228; 12X.240.229; 12.L.240.230; 12X.240.231; 12X.240.236; 12X.240.237; 12X.240.238; 12X.240.239; 12X.240.154; 12X.240.157; 12X.240.166; 12X.240.169; 12X.240.172; 12X.240.175; 12X.240.240; 12X.240.244; 12X.244.228; 12X.244.229; 12X.244.230; 12X.244.231; 12X.244.236; 12X.244.237; 12X.244.238; 12X.244.239; 12X.244.154; 12X.244.157; 12X.244.166; 12X.244.169; 12X.244.172; 12X.244.175; 12X.244.240; 12X.244.244;

Prodrugs of 12.O

12.O.228.228; 12.O.228.229; 12.O.228.230; 12.O.228.231; 12.O.228.236; 12.O.228.237; 12.O.228.238; 12.O.228.239; 12.O.228.154; 12.O.228.157; 12.O.228.166; 12.O.228.169; 12.O.228.172; 12.O.228.175; 12.O.228.240; 12.O.228.244; 12.O.229.228; 12.O.229.229; 12.O.229.230; 12.O.229.231; 12.O.229.236; 12.O.229.237; 12.O.229.238; 12.O.229.239; 12.O.229.154; 12.O.229.157; 12.O.229.166; 12.O.229.169; 12.O.229.172; 12.O.229.175; 12.O.229.240; 12.O.229.244; 12.O.230.228; 12.O.230.229; 12.O.230.230; 12.O.230.231; 12.O.230.236; 12.O.230.237; 12.O.230.238; 12.O.230.239; 12.O.230.154; 12.O.23Q.157; 12.O.230.166; 12.O.230.169; 12.O.230.172; 12.O.230.175; 12.O.230.240; 12.O.230.244; 12.O.231.228; 12.O.231.229; 12.O.231.230; 12.O.231.231; 12.O.231.236; 12.O.231.237; 12.O.231.238; 12.O.231.239; 12.O.231.154; 12.0.231.157; 12.O.231.166; 12.O.231.169; 12.O.231.172; 12.O.231.175; 12.O.231.240; 12.O.231.244; 12.O.236.228; 12.O.236.229; 12.O.236.230; 12.O.236.231; 12.O.236.236; 12.O.236.237; 12.O.236.238; 12.O.236.239; 12.O.236.154; 12.O.236.157; 12.O.236.166; 12.O.236.169; 12.O.236.172; 12.O.236.175; 12.O.236.240; 12.O.236.244; 12.O.237.228; 12.O.237.229; 12.O.237.230; 12.O.237.231; 12.O.237.236; 12.O.237.237; 12.O.237.238; 12.O.237.239; 12.O.237.154; 12.O.237.157; 12.O.237.166; 12.O.237.169; 12.O.237.172; 12.O.237.175; 12.O.237.240; 12.O.237.244; 12.O.238.228; 12.O.238.229; 12.O.238.230; 12.O.238.231; 12.O.238.236; 12.O.238.237; 12.O.238.238; 12.O.238.239; 12.O.238.154; 12.O.238.157; 12.O.238.166; 12.O.238.169; 12.O.238.172; 12.O.238.175; 12.O.238.240; 12.O.238.244; 12.O.239.228; 12.Q.239.229; 12.O.239.230; 12.O.239.231; 12.O.239.236; 12.O.239.237; 12.O.239.238; 12.O.239.239; 12.O.239.154; 12.O.239.157; 12.O.239.166; 12.O.239.169; 12.O.239.172; 12.O.239.175; 12.O.239.240; 12.O.239.244; 12.O.154.228; 12.O.154.229; 12.O.154.230; 12.O.154.231; 12.O.154.236; 12.O.154.237; 12.O.154.238; 12.O.154.239; 12.O.154.154; 12.O.154.157; 12.O.154.166; 12.O.154.169; 12.O.154.172; 12.O.154.175; 12.O.154.240; 12.O.154.244; 12.O.157.228; 12.O.157.229; 12.O.157.230; 12.O.157.231; 12.O.157.236; 12.O.157.237; 12.O.157.238; 12.O.157.239; 12.O.157.154; 12.O.157.157; 12.O.157.166; 12.O.157.169; 12.O.157.172; 12.O.157.175; 12.O157.240; 12.O.157.244; 12.O.166.228; 12.O.166.229; 12.O.166.230; 12.O.166.231; 12.O.166.236; 12.O.166.237; 12.O.166.238; 12.O.166.239; 12.O.166.154; 12.O-166.157; 12.O.166.166; 12.O.166.169; 12.O.166.172; 12.0-166.175; 12.O.166.240; 12.O.166.244; 12.O.169.228; 12.O.169.229; 12.O.169.230; 12.O.169.231; 12.O.169.236; 12.O.169.237; 12.O.169.238; 12.O.169.239; 12.O.169.154; 12.O.169.157; 12.O.169.166; 12.O.169.169; 12.O.169.172; 12.O.169.175; 12.O.169.240; 12.O.169.244; 12.O.172.228; 12.O.172.229; 12.O.172.230; 12.O.172.231; 12.O.172.236; 12.O-172.237; 12.0172.238; 12.O-172.239; 12.O.172.154; 12.O-172.157; 12.O.172.166; 12.O.172.169; 12.O.172.172; 12.O.172.175; 12.O.172.240; 12.O.172.244; 12.0.175.228; 12.O.175.229; 12.O.175.230; 12.O.175.231; 12.O-175.236; 12.O.175.237; 12.O.175.238; 12.O.175.239; 12.O.175.154; 12.O.175.157; 12.O.175.166; 12.O.175.169; 12.O.175.172; 12.O.175.175; 12.O.175.240; 12.O.175.244; 12.O.240.228; 12.O.240.229; 12.O.240.230; 12.O.240.231; 12.O.240.236; 12.O.240.237; 12.O.240.238; 12.O.240.239; 12.O.240.154; 12.O.240.157; 12.O.240.166; 12.O.240.169; 12.O.240.172; 12.O.240.175; 12.O.240.240; 12.O.240.244; 12.O.244.228; 12.O.244.229 ; 12.O.244.230; 12.O.244.231; 12.O.244.236; 12.O.244.237; 12.O.244.238; 12.O.244.239; 12.O.244.154; 12.O.244.157; 12.O.244.166; 12.O.244.169; 12.O.244.172; 12.O.244.175; 12.O.244.240; 12.O.244.244;

Prodrugs of 12.P 12.P.228.228; 12.P.228.229; 12.P.228.230; 12.P.228.231; 12.P.228.236; 12.P.228.237; 12.P.228.238; 12.P.228.239; 12.P.228.154; 12.P.228.157; 12.P.228.166; 12.P.228.169; 12.P.228.172; 12.P.228.175; 12.P.228.240; 12.P.228.244; 12.P.229.228; 12.P.229.229; 12.P.229.230; 12.P.229.231; 12.P.229.236; 12.P.229.237; 12.P.229.238; 12.P.229.239; 12.P.229.154; 12.P.229.157; 12.P.229.166; 12.P.229.169; 12.P.229.172; 12.P.229.175; 12.P.229.240; 12.P.229.244; 12.P.230.228; 12.P.230.229; 12.P.230.230; 12.P.230.231; 12.P.230.236; 12.P.230.237; 12.P.230.238; 12.P.230.239; 12.P.230.154; 12.P.230.157; 12.P.230.166; 12.P.230.169; 12.P.230.172; 12.P.230.175; 12.P.230.240; 12.P.230.244; 12.P.231.228; 12.P.231.229; 12.P.231.230; 12.P.231.231; 12.P.231.236; 12.P.231.237; 12.P.231.238; 12.P.231.239; 12.P.231.154; 12.P.231.157; 12.P.231.166; 12.P.231.169; 12.P.231.172; 12.P.231.175; 12.P.231.240; 12.P.231.244; 12.P.236.228; 12.P.236.229; 12.P.236.230; 12.P.236.231; 12.P.236.236; 12.P.236.237; 12.P.236.238; 12.P.236.239; 12.P.236.154; 12.P.236.157; 12.P.236.166; 12.P.236.169; 12.P.236.172; 12.P.236.175; 12.P.236.240; 12.P.236.244; 12.P.237.228; 12.P.237.229; 12.P.237.230; 12.P.237.231; 12.P.237.236; 12.P.237.237; 12.P.237.238; 12.P.237.239; 12.P.237.154; 12.P.237.157; 12.P.237.166; 12.P.237.169; 12.P.237.172; 12.P.237.175; 12.P.237.240; 12.P.237.244; 12.P.238.228; 12.P.238.229; 12.P.238.230; 12.P.238.231; 12.P.238.236; 12.P.238.237; 12.P.238.238; 12.P.238.239; 12.P.238.154; 12.P.238.157; 12.P.238.166; 12.P.238.169; 12.P.238.172; 12.P.238.175; 12.P.238.240; 12.P.238.244; 12.P.239.228; 12.P.239.229; 12.P.239.230; 12.P.239.231; 12.P.239.236; 12.P.239.237; 12.P.239.238; 12.P.239.239; 12.P.239.154; 12.P.239.157; 12.P.239.166; 12.P.239.169; 12.P.239.172; 12.P.239.175; 12.P.239.240; 12.P.239.244; 12.P.154.228; 12.P.154.229; 12.P.154.230; 12.P.154.231; 12.P.154.236; 12.P.154.237; 12.P.154.238; 12.P.154.239; 12.P.154.154; 12.P.154.157; 12.P.154.166; 12.P.154.169; 12.P.154.172; 12.P.154.175; 12.P.154.240; 12.P.154.244; 12.P.157.228; 12.P.157.229; 12.P.157.230; 12.P.157.231; 12.P.157.236; 12.P.157.237; 12.P.157.238; 12.P.157.239; 12.P.157.154; 12.P.157.157; 12.P.157.166; 12.P.157.169; 12.P.157.172; 12.P.157.175; 12.P.157.240; 12.P.157.244; 12.P.166.228; 12.P.166.229; 12.P.166.230; 12.P.166.231; 12.P.166.236; 12.P.166.237; 12.P.166.238; 12.P.166.239; 12.P.166.154; 12.P.166.157; 12.P.166.166; 12.P.166.169; 12.P.166.172; 12.P.166.175; 12.P.166.240; 12.P.166.244; 12.P.169.228; 12.P.169.229; 12.P.169.230; 12.P.169.231; 12.P.169.236; 12.P.169.237; 12.P.169.238; 12.P.169.239; 12.P.169.154; 12.P.169.157; 12.P.169.166; 12.P.169.169; 12.P.169.172; 12.P.169.175; 12.P.169.240; 12.P.169.244; 12.P.172.228; 12.P.172.229; 12.P.172.230; 12.P.172.231; 12.P.172.236; 12.P.172.237; 12.P.172.238; 12.P.172.239; 12.P.172.154; 12.P.172.157; 12.P.172.166; 12.P.172.169; 12.P.172.172; 12.P.172.175; 12.P.172.240; 12.P.172.244; 12.P.175.228; 12.P.175.229; 12.P.175.230; 12.P.175.231; 12.P.175.236; 12.P.175.237; 12.P.175.238; 12.P.175.239; 12.P.175.154; 12.P.175.157; 12.P.175.166; 12.P.175.169; 12.P.175.172; 12.P.175.175; 12.P.175.240; 12.P.175.244; 12.P.240.228; 12.P.240.229; 12.P.240.230; 12.P.240.231; 12.P.240.236; 12.P.240.237; 12.P.240.238; 12.P.240.239; 12.P.240.154; 12.P.240.157; 12.P.240.166; 12.P.240.169; 12.P.240.172; 12.P.240.175; 12.P.240.240; 12.P.240.244; 12.P.244.228; 12.P.244.229; 12.P.244.230; 12.P.244.231; 12.P.244.236; 12.P.244.237; 12.P.244.238; 12.P.244.239; 12.P.244.154; 12.P.244.157; 12.P.244.166; 12.P.244.169; 12.P.244.172; 12.P.244.175; 12.P.244.240; 12.P.244.244;

Prodrugs of 12.U 12.U.228.228; 12.U.228.229; 12.U.228.230; 12.U.228.231; 12.U.228.236; 12.U.228.237; 12.U.228.238; 12.U.228.239; 12.U.228.154; 12.U.228.157; 12.U.228.166; 12.U.228.169; 12.U.228.172; 12.U.228.175; 12.U.228.240; 12.U.228.244; 12.U.229.228; 12.U.229.229; 12.U.229.230; 12.U.229.231; 12.U.229.236; 12.U.229.237; 12.U.229.238; 12.U.229.239; 12.U.229.154; 12.U.229.157; 12.U.229.166; 12.U.229.169; 12.U.229.172; 12.U.229.175; 12.U.229.240; 12.U.229.244; 12.U.230.228; 12.U.230.229; 12.U.230.230; 12.U.230.231; 12.U.230.236; 12.U.230.237; 12.U.230.238; 12.U.230.239; 12.U.230.154; 12.U.230.157; 12.U.230.166; 12.U.230.169; 12.U.230.172; 12.U.230.175; 12.U.230.240; 12.U.230.244; 12.U.231.228; 12.U.231.229; 12.U.231.230; 12.U.231.231; 12.U.231.236; 12.U.231.237; 12.U.231.238; 12.U.231.239; 12.U.231.154; 12.U.231.157; 12.U.231.166; 12.U.231.169; 12.U.231.172; 12.U.231.175; 12.U.231.240; 12.U.231.244; 12.U.236.228; 12.U.236.229; 12.U.236.230; 12.U.236.231; 12.U.236.236; 12.U.236.237; 12.U.236.238; 12.U.236.239; 12.U.236.154; 12.U.236.157; 12.U.236.166; 12.U.236.169; 12.U.236.172; 12.U.236.175; 12.U.236.240; 12.U.236.244; 12.U.237.228; 12.U.237.229; 12.U.237.230; 12.U.237.231; 12.U.237.236; 12.U.237.237; 12.U.237.238; 12.U.237.239; 12.U.237.154; 12.U.237.157; 12.U.237.166; 12.U.237.169; 12.U.237.172; 12.U.237.175; 12.U.237.240; 12.U.237.244; 12.U.238.228; 12.U.238.229; 12.U.238.230; 12.U.238.231; 12.U.238.236; 12.U.238.237; 12.U.238.238; 12.U.238.239; 12.U.238.154; 12.U.238.157; 12.U.238.166; 12.U.238.169; 12.U.238.172; 12.U.238.175; 12.U.238.240; 12.U.238.244; 12.U.239.228; 12.U.239.229; 12.U.239.230; 12.U.239.231; 12.U.239.236; 12.U.239.237; 12.U.239.238; 12.U.239.239; 12.U.239.154; 12.U.239.157; 12.U.239.166; 12.U.239.169; 12.U.239.172; 12.U.239.175; 12.U.239.240; 12.U.239.244; 12.U.154.228; 12.U.154.229; 12.U.154.230; 12.U.154.231; 12.U.154.236; 12.U.154.237; 12.U.154.238; 12.U.154.239; 12.U.154.154; 12.U.154.157; 12.U.154.166; 12.U.154.169; 12.U.154.172; 12.U.154.175; 12.U.154.240; 12.U.154.244; 12.U.157.228; 12.U.157.229; 12.U.157.230; 12.U.157.231; 12.U.157.236; 12.U.157.237; 12.U.157.238; 12.U.157.239; 12.U.157.154; 12.U.157.157; 12.U.157.166; 12.U.157.169; 12.U.157.172; 12.U.157.175; 12.U.157.240; 12.U.157.244; 12.U.166.228; 12.U.166.229; 12.U.166.230; 12.U.166.231; 12.U.166.236; 12.U.166.237; 12.U.166.238; 12.U.166.239; 12.U.166.154; 12.U.166.157; 12.U.166.166; 12.U.166.169; 12.U.166.172; 12.U.166.175; 12.U.166.240; 12.U.166.244; 12.U.169.228; 12.U.169.229; 12.U.169.230; 12.U.169.231; 12.U.169.236; 12.U.169.237; 12.U.169.238; 12.U.169.239; 12.U.169.154; 12.U.169.157; 12.U.169.166; 12.U.169.169; 12.U.169.172; 12.U.169.175; 12.U.169.240; 12.U.169.244; 12.U.172.228; 12.U.172.229; 12.U.172.230; 12.U.172.231; 12.U.172.236; 12.U.172.237; 12.U.172.238; 12.U.172.239; 12.U.172.154; 12.U.172.157; 12.U.172.166; 12.U.172.169; 12.U.172.172; 12.U.172.175; 12.U.172.240; 12.U.172.244; 12.U.175.228; 12.U.175.229; 12.U.175.230; 12.U.175.231; 12.U.175.236; 12.U.175.237; 12.U.175.238; 12.U.175.239; 12.U.175.154; 12.U.175.157; 12.U.175.166; 12.U.175.169; 12.U.175.172; 12.U.175.175; 12.U.175.240; 12.U.175.244; 12.U.240.228; 12.U.240.229; 12.U.240.230; 12.U.240.231; 12.U.240.236; 12.U.240.237; 12.U.240.238; 12.U.240.239; 12.U.240.154; 12.U.240.157; 12.U.240.166; 12.U.240.169; 12.U.240.172; 12.U.240.175; 12.U.240.240; 12.U.240.244; 12.U.244.228; 12.U.244.229; 12.U.244.230; 12.U.244.231; 12.U.244.236; 12.U.244.237; 12.U.244.238; 12.U.244.239; 12.U.244.154; 12.U.244.157; 12.U.244.166; 12.U.244.169; 12.U.244.172; 12.U.244.175; 12.U.244.240; 12.U.244.244;

Prodrugs of 12.CD

12.CD.228.228; 12.CD.228.229; 12.CD.228.230; 12.CD.228.231; 12.CD.228.236; 12.CD.228.237; 12.CD.228.238; 12.CD.228.239; 12.CD.228.154; 12.CD.228.157; 12.CD.228.166; 12.CD.228.169; 12.CD.228.172; 12.CD.228.175; 12.CD.228.240; 12.CD.228.244; 12.CD.229.228; 12.CD.229.229; 12.CD.229.230; 12.CD.229.231; 12.CD.229.236; 12.CD.229.237; 12.CD.229.238; 12.CD.229.239; 12.CD.229.154; 12.CD.229.157; 12.CD.229.166; 12.CD.229.169; 12.CD.229.172; 12.CD.229.175; 12.CD.229.240; 12.CD.229.244; 12.CD.230.228; 12.CD.230.229; 12.CD.230.230; 12.CD.230.231; 12.CD.230.236; 12.CD.230.237; 12.CD.230.238; 12.CD.230.239; 12.CD.230.154; 12.CD.230.157; 12.CD.230.166; 12.CD.230.169; 12.CD.230.172; 12.CD.230.175; 12.CD.230.240; 12.CD.230.244; 12.CD.231.228; 12.CD.231.229; 12.CD.231.230; 12.CD.231.231; 12.CD.231.236; 12.CD.231.237; 12.CD.231.238; 12.CD.231.239; 12.CD.231.154; 12.CD.231.157; 12.CD.231.166; 12.CD.231.169; 12.CD.231.172; 12.CD.231.175; 12.CD.231.240; 12.CD.231.244; 12.CD.236.228; 12.CD.236.229; 12.CD.236.230; 12.CD.236.231; 12.CD.236.236; 12.CD.236.237; 12.CD.236.238; 12.CD.236.239; 12.CD.236.154; 12.CD.236.157; 12.CD.236.166; 12.CD.236.169; 12.CD.236.172; 12.CD.236.175; 12.CD.236.240; 12.CD.236.244; 12.CD.237.228; 12.CD.237.229; 12.CD.237.230; 12.CD.237.231; 12.CD.237.236; 12.CD.237.237; 12.CD.237.238; 12.CD.237.239; 12.CD.237.154; 12.CD.237.157; 12.CD.237.166; 12.CD.237.169; 12.CD.237.172; 12.CU237.175; 12.CD.237.240; 12.CD.237.244; 12.CD.238.228; 12.CD.238.229; 12.CD.238.230; 12.CD.238.231; 12.CD.238.236; 12.CD.238.237; 12.CD.238.238; 12.CD.238.239; 12.CD.238.154; 12.CD.238.157; 12.CD.238.166; 12.CD.238.169; 12.CD.238.172; 12.CD.238.175; 12.CD.238.240; 12.CD.238.244; 12.CD.239.228; 12.CD.239.229; 12.CD.239.230; 12.CD.239.231; 12.CD.239.236; 12.CD.239.237; 12.CD.239.238; 12.CD.239.239; 12.CD.239.154; 12.CD.239.157; 12.CD.239.166; 12.CD.239.169; 12.CD.239.172; 12.CD.239.175; 12.CD.239.240; 12.CD.239.244; 12.CD.154.228; 12.CD.154.229; 12.CD.154.230; 12.CD.154.231; 12.CD.154.236; 12.CD.154.237; 12.CD.154.238; 12.CD.154.239; 12.CD.154.154; 12.CD.154.157; 12.CD.154.166; 12.CD.154.169; 12.CD.154.172; 12.CD.154.175; 12.CD.154.240; 12.CD.154.244; 12.CD.157.228; 12.CD.157.229; 12.CD.157.230; 12.CD.157.231; 12.CD.157.236; 12.CD.157.237; 12.CD.157.238; 12.CD.157.239; 12.CD.157.154; 12.CD.157.157; 12.CD.157.166; 12.CD.157.169; 12.CD.157.172; 12.CD.157.175; 12.CD.157.240; 12.CD.157.244; 12.CD.166.228; 12.CD.166.229; 12.CD.166.230; 12.CD.166.231; 12.CD.166.236; 12.CD.166.237; 12.CD.166.238; 12.CD.166.239; 12.CD.166.154; 12.CD.166.157; 12.CD.166.166; 12.CD.166.169; 12.CD.166.172; 12.CD.166.175; 12.CD.166.240; 12.CD.166.244; 12.CD.169.228; 12.CD.169.229; 12.CD.169.230; 12.CD.169.231; 12.CD.169.236; 12.CD.169.237; 12.CD.169.238; 12.CD.169.239; 12.CD.169.154; 12.CD.169.157; 12.CD.169.166; 12.CD.169.169; 12.CD.169.172; 12.CD.169.175; 12.CD.169.240; 12.CD.169.244; 12.CD.172.228; 12.CD.172.229; 12.CD.172.230; 12.CD.172.231; 12.CD.172.236; 12.CD.172.237; 12.CD.172.238; 12.CD.172.239; 12.CD.172.154; 12.CD.172.157; 12.CD.172.166; 12.CD.172.169; 12.CD.172.172; 12.CD.172.175; 12.CD.172.240; 12.CD.172.244; 12.CD.175.228; 12.CD.175.229; 12.CD.175.230; 12.CD.175.231; 12.CD.175.236; 12.CD.175.237; 12.CD.175.238; 12.CD.175.239; 12.CD.175.154; 12.CD.175.157; 12.CD.175.166; 12.CD.175.169; 12.CD.175.172; 12.CD.175.175; 12.CD.175.240; 12.CD.175.244; 12.CD.240.228; 12.CD.240.229; 12.CD.240.230; 12.CD.240.231; 12.CD.240.236; 12.CD.240.237; 12.CD.240.238; 12.CD.24Q.239; 12.CD.240.154; 12.CD.240.157; 12.CD.240.166; 12.CD.240.169; 12.CD.240.172; 12.CD.240.175; 12.CD.240.240; 12.CD.240.244; 12.CD.244.228; 12.CD.244.229; 12.CD.244.230; 12.CD.244.231; 12.CD.244.236; 12.CD.244.237; 12.CD.244.238; 12.CD.244.239; 12.CD.244.154; 12.CD.244.157; 12.CD.244.166; 12.CD.244.169; 12.CD.244.172; 12.CD.244.175; 12.CD.244.240; 12.CD.244.244;

Prodrugs of 12.EB

12.EB.228.228; 12.EB.228.229; 12.EB.228.230; 12.EB.228.231; 12.EB.228.236; 12.EB.228.237; 12.EB.228.238; 12.EB.228.239; 12.EB.228.154; 12.EB.228.157; 12.EB.228.166; 12.EB.228.169; 12.EB.228.172; 12.EB.228.175; 12.EB.228.240; 12.EB.228.244; 12.EB.229.228; 12.EB.229.229; 12.EB.229.230; 12.EB.229.231; 12.EB.229.236; 12.EB.229.237; 12.EB.229.238; 12.EB.229.239; 12.EB.229.154; 12.EB.229.157; 12.EB.229.166; 12.EB.229.169; 12.EB.229.172; 12.EB.229.175; 12.EB.229.240; 12.EB.229.244; 12.EB.230.228; 12.EB.230.229; 12.EB.230.230; 12.EB.230.231; 12.EB.230.236; 12.EB.230.237; 12.EB.230.238; 12.EB.230.239; 12.EB.230.154; 12.EB.230.157; 12.EB.230.166; 12.EB.230.169; 12.EB.230.172; 12.EB.230.175; 12.EB.230.240; 12.EB.230.244; 12.EB.231.228; 12.EB.231.229; 12.EB.231.230; 12.EB.231.231; 12.EB.231.236; 12.EB.231.237; 12.EB.231.238; 12.EB.231.239; 12.EB.231.154; 12.EB.231.157; 12.EB.231.166; 12.EB.231.169; 12.EB.231.172; 12.EB.231.175; 12.EB.231.240; 12.EB.231.244; 12.EB.236.228; 12.EB.236.229; 12.EB.236.230; 12.EB.236.231; 12.EB.236.236; 12.EB.236.237; 12.EB.236.238; 12.EB.236.239; 12.EB.236.154; 12.EB.236.157; 12.EB.236.166; 12.EB.236.169; 12.EB.236.172; 12.EB.236.175; 12.EB.236.240; 12.EB.236.244; 12.EB.237.228; 12.EB.237.229; 12.EB.237.230; 12.EB.237.231; 12.EB.237.236; 12.EB.237.237; 12.EB.237.238; 12.EB.237.239; 12.EB.237.154; 12.EB.237.157; 12.EB.237.166; 12.EB.237.169; 12.EB.237.172; 12.EB.237.175; 12.EB.237.240; 12.EB.237.244; 12.EB.238.228; 12.EB.238.229; 12.EB.238.230; 12.EB.238.231; 12.EB.238.236; 12.EB.238.237; 12.EB.238.238; 12.EB.238.239; 12.EB.238.154; 12.EB.238.157; 12.EB.238.166; 12.EB.238.169; 12.EB.238.172; 12.EB.238.175; 12.EB.238.240; 12.EB.238.244; 12.EB.239.228; 12.EB.239.229; 12.EB.239.230; 12.EB.239.231; 12.EB.239.236; 12.EB.239.237; 12.EB.239.238; 12.EB.239.239; 12.EB.239.154; 12.EB.239.157; 12.EB.239.166; 12.EB.239.169; 12.EB.239.172; 12.EB.239.175; 12.EB.239.240; 12.EB.239.244; 12.EB.154.228; 12.EB.154.229; 12.EB.154.230; 12.EB.154.231; 12.EB.154.236; 12.EB.154.237; 12.EB.154.238; 12.EB.154.239; 12.EB.154.154; 12.EB.154.157; 12.EB.154.166; 12.EB.154.169; 12.EB.154.172; 12.EB.154.175; 12.EB.154.240; 12.EB.154.244; 12.EB.157.228; 12.EB.157.229; 12.EB.157.230; 12.EB.157.231; 12.EB.157.236; 12.EB.157.237; 12.EB.157.238; 12.EB.157.239; 12.EB.157.154; 12.EB.157.157; 12.EB.157.166; 12.EB.157.169; 12.EB.157.172; 12.EB.157.175; 12.EB.157.240; 12.EB.157.244; 12.EB.166.228; 12.EB.166.229; 12.EB.166.230; 12.EB.166.231; 12.EB.166.236; 12.EB.166.237; 12.EB.166.238; 12.EB.166.239; 12.EB.166.154; 12.EB.166.157; 12.EB.166.166; 12.EB.166.169; 12.EB.166.172; 12.EB.166.175; 12.EB.166.240; 12.EB.166.244; 12.EB.169.228; 12.EB.169.229; 12.EB.169.230; 12.EB.169.231; 12.EB.169.236; 12.EB.169.237; 12.EB.169.238; 12.EB.169.239; 12.EB.169.154; 12.EB.169.157; 12.EB.169.166; 12.EB.169.169; 12.EB.169.172; 12.EB.169.175; 12.EB.169.240; 12.EB.169.244; 12.EB.172.228; 12.EB.172.229; 12.EB.172.230; 12.EB.172.231; 12.EB.172.236; 12.EB.172.237; 12.EB.172.238; 12.EB.172.239; 12.EB.172.154; 12.EB.172.157; 12.EB.172.166; 12.EB.172.169; 12.EB.172.172; 12.EB.172.175; 12.EB.172.240; 12.EB.172.244; 12.EB.175.228; 12.EB.175.229; 12.EB.175.230; 12.EB.175.231; 12.EB.175.236; 12.EB.175.237; 12.EB.175.238; 12.EB.175.239; 12.EB.175.154; 12.EB.175.157; 12.EB.175.166; 12.EB.175.169; 12.EB.175.172; 12.EB.175.175; 12.EB.175.240; 12.EB.175.244; 12.EB.240.228; 12.EB.240.229; 12.EB.240.230; 12.EB.24Q.231; 12.EB.240.236; 12.EB.240.237; 12.EB.240.238; 12.EB,240.239; 12.EB.240.154; 12.EB.240.157; 12.EB.240.166; 12.EB.240.169; 12.EB.240.172; 12.EB.240.175; 12.EB.240.240; 12.EB.240.244; 12.EB.244.228; 12.EB.244.229; 12.EB.244.230; 12.EB.244.231; 12.EB.244.236; 12.EB.244.237; 12.EB.244.238; 12.EB.244.239; 12.EB.244.154; 12.EB.244.157; 12.EB.244.166; 12.EB.244.169; 12.EB.244.172; 12.EB.244.175; 12.EB.244.240; 12.EB.244.244.

Prodrugs of 13.B

13.B.228.228; 13.B.228.229; 13.B.228.230; 13.B.228.231; 13.B.228.236; 13.B.228.237; 13.B.228.238; 13.B.228.239; 13.B.228.154; 13.B.228.157; 13.B.228.166; 13.B.228.169; 13.B.228.172; 13.B.228.175; 13.B.228.240; 13.B.228.244; 13.B.229.228; 13.B.229.229; 13.B.229.230; 13.B.229.231; 13.B.229.236; 13.B.229.237; 13.B.229.238; 13.B.229.239; 13.B.229.154; 13.B.229.157; 13.B.229.166; 13.B.229.169; 13.B.229.172; 13.B.229.175; 13.B.229.240; 13.B.229.244; 13.B.230.228; 13.B.230.229; 13.B.230.230; 13.B.230.231; 13.B.230.236; 13.B.230.237; 13.B.230.238; 13.B.230.239; 13.B.23Q.154; 13.B.230.157; 13.B.230.166; 13.B.230.169; 13.B.230.172; 13.B.230.175; 13.B.230.240; 13.B.230.244; 13.B.231.228; 13.B.231.229; 13.B.231.230; 13.B.231.231; 13.B.231.236; 13.B.231.237; 13.B.231.238; 13.B.231.239; 13.B.231.154; 13.B.231.157; 13.B.231.166; 13.B.231.169; 13.B.231.172; 13.B.231.175; 13.B.231.240; 13.B.231.244; 13.B.236.228; 13.B.236.229; 13.B.236.230; 13.B.236.231; 13.B.236.236; 13.B.236.237; 13.B.236.238; 13.B.236.239; 13.B.236.154; 13.B.236.157; 13.B.236.166; 13.B.236.169; 13.B.236.172; 13.B.236.175; 13.B.236.240; 13.B.236.244; 13.B.237.228; 13.B.237.229; 13.B.237.230; 13.B.237.231; 13.B.237.236; 13.B.237.237; 13.B.237.238; 13.B.237.239; 13.B.237.154; 13.B.237.157; 13.B.237.166; 13.B.237.169; 13.B.237.172; 13.B.237.175; 13.B.237.240; 13.B.237.244; 13.B.238.228; 13.B.238.229; 13.B.238.230; 13.B.238.231; 13.B.238.236; 13.B.238.237; 13.B.238.238; 13.B.238.239; 13.B.238.154; 13.B.238.157; 13.B.238.166; 13.B.238.169; 13.B.238.172; 13.B.238.175; 13.B.238.240; 13.B.238.244; 13.B.239.228; 13.B.239.229; 13.B.239.230; 13.B.239.231; 13.B.239.236; 13.B.239.237; 13.B.239.238; 13.B.239.239; 13.B.239.154; 13.B.239.157; 13.B.239.166; 13.B.239.169; 13.B.239.172; 13.B.239.175; 13.B.239.240; 13.B.239.244; 13.B.154.228; 13.B.154.229; 13.B.154.230; 13.B.154.231; 13.B.154.236; 13.B.154.237; 13.B.154.238; 13.B.154.239; 13.B.154.154; 13.B.154.157; 13.B.154.166; 13.B.154.169; 13.B.154.172; 13.B.154.175; 13.B.154.240; 13.B.154.244; 13.B.157.228; 13.B.157.229; 13.B.157.230; 13.B.157.231; 13.B.157.236; 13.B.157.237; 13.B.157.238; 13.B.157.239; 13.B.157.154; 13.B.157.157; 13.B.157.166; 13.B.157.169; 13.B.157.172; 13.B.157.175; 13.B.157.240; 13.B.157.244; 13.B.166.228; 13.B.166.229; 13.B.166.230; 13.B.166.231; 13.B.166.236; 13.B.166.237; 13.B.166.238; 13.B.166.239; 13.B.166.154; 13.B.166.157; 13.B.166.166; 13.B.166.169; 13.B.166.172; 13.B.166.175; 13.B.166.240; 13.B.166.244; 13.B.169.228; 13.B.169.229; 13.B.169.230; 13.B.169.231; 13.B.169.236; 13.B.169.237; 13.B.169.238; 13.B.169.239; 13.B.169.154; 13.B.169.157; 13.B.169.166; 13.B.169.169; 13.B.169.172; 13.B.169.175; 13.B.169.240; 13.B.169.244; 13.B.172.228; 13.B.172.229; 13.B.172.230; 13.B.172.231; 13.B.172.236; 13.B.172.237; 13.B.172.238; 13.B.172.239; 13.B.172.154; 13.B.172.157; 13.B.172.166; 13.B.172.169; 13.B.172.172; 13.B.172.175; 13.B.172.240; 13.B.172.244; 13.B.175.228; 13.B.175.229; 13.B.175.230; 13.B.175.231; 13.B.175.236; 13.B.175.237; 13.B.175.238; 13.B.175.239; 13.B.175.154; 13.B.175.157; 13.B.175.166; 13.B.175.169; 13.B.175.172; 13.B.175.175; 13.B.175.240; 13.B.175.244; 13.B.240.228; 13.B.240.229; 13.B.240.230; 13.B.240.231; 13.B.240.236; 13.B.240.237; 13.B.240.238; 13.B.24Q.239; 13.B.240.154; 13.B.240.157; 13.B.240.166; 13.B.240.169; 13.B.240.172; 13.B.240.175; 13.B.240.240; 13.B.240.244; 13.B.244.228; 13.B.244.229; 13.B.244.230; 13.B.244.231; 13.B.244.236; 13.B.244.237; 13.B.244.238; 13.B.244.239; 13.B.244.154; 13.B.244.157; 13.B.244.166; 13.B.244.169; 13.B.244.172; 13.B.244.175; 13.B.244.240; 13.B.244.244;

Prodrugs of 13.D

13.D.228.228; 13.D.228.229; 13.D.228.230; 13.D.228.231; 13.D.228.236; 13.D.228.237; 13.D.228.238; 13.D.228.239; 13.D.228.154; 13.D.228.157; 13.D.228.166; 13.D.228.169; 13.D.228.172; 13.D.228.175; 13.D.228.240; 13.D.228.244; 13.D.229.228; 13.D.229.229; 13.D.229.230; 13.D.229.231; 13.D.229.236; 13.D.229.237; 13.D.229.238; 13.D.229.239; 13.D.229.154; 13.D.229.157; 13.D.229.166; 13D.229.169; 13.D.229.172; 13.D.229.175; 13.D.229.240; 13.D.229.244; 13.D.230.228; 13.D.230.229; 13.D.230.230; 13.D.230.231; 13.D.230.236; 13.D.230.237; 13.D.230.238; 13.D.23Q.239; 13.D.230.154; 13.D.230.157; 13.D.230.166; 13.D.230.169; 13.D.230.172; 13.D.230.175; 13.D.230.240; 13.D.23Q.244; 13.D.231.228; 13.D.231.229; 13.D.231.230; 13.D.231.231; 13.D.231.236; 13.D.231.237; 13.D.231.238; 13.D.231.239; 13.D.231.154; 13.D.231.157; 13.D.231.166; 13.D.231.169; 13.D.231.172; 13.D.231.175; 13.D.231.240; 13.D.231.244; 13.D.236.228; 13.D.236.229; 13.D.236.230; 13.D.236.231; 13.D.236.236; 13.D.236.237; 13.D.236.238; 13.D.236.239; 13.D.236.154; 13.D.236.157; 13.D.236.166; 13.D.236.169; 13.D.236.172; 13.D.236.175; 13.D.236.240; 13.D.236.244; 13.D.237.228; 13.D.237.229; 13.D.237.230; 13.D.237.231; 13.D.237.236; 13.D.237.237; 13.D.237.238; 13.D.237.239; 13.D.237.154; 13.D.237.157; 13.D.237.166; 13.D.237.169; 13.D.237.172; 13.D.237.175; 13.D.237.240; 13.D.237.244; 13.D.238.228; 13.D.238.229; 13.D.238.230; 13.D.238.231; 13.D.238.236; 13.D.238.237; 13.D.238.238; 13.D.238.239; 13.D.238.154; 13.D.238.157; 13.D.238.166; 13.D.238.169; 13.D.238.172; 13.D.238.175; 13.D.238.240; 13.D.238.244; 13.D.239.228; 13.D.239.229; 13.D.239.230; 13.D.239.231; 13.D.239.236; 13.D.239.237; 13.D.239.238; 13.D.239.239; 13.D.239.154; 13.D.239.157; 13.D.239.166; 13.D.239.169; 13.D.239.172; 13.D.239.175; 13.D.239.240; 13.D.239.244; 13.D.154.228; 13.D.154.229; 13.D.154.230; 13.D.154.231; 13.D.154.236; 13.D.154.237; 13.D.154.238; 13.D.154.239; 13.D.154.154; 13.D.154.157; 13.D.154.166; 13.D.154.169; 13.D.154.172; 13.D.154.175; 13.D.154.240; 13.D.154.244; 13.D.157.228; 13.D.157.229; 13.D.157.230; 13.D.157.231; 13.D.157.236; 13.D.157.237; 13.D.157.238; 13.D.157.239; 13.D.157.154; 13.D.157.157; 13.D.157.166; 13.D.157.169; 13.D.157.172; 13.D.157.175; 13.D.157.240; 13.D.157.244; 13.D.166.228; 13.D.166.229; 13.D.166.230; 13.D.166.231; 13.D.166.236; 13.D.166.237; 13.D.166.238; 13.D.166.239; 13.D.166.154; 13.D.166.157; 13.D.166.166; 13.D.166.169; 13.D.166.172; 13.D.166.175; 13.D.166.240; 13.D.166.244; 13.D.169.228; 13.D.169.229; 13.D.169.230; 13.D.169.231; 13.D.169.236; 13.D.169.237; 13.D.169.238; 13.D.169.239; 13.D.169.154; 13.D.169.157; 13.D.169.166; 13.D.169.169; 13.D.169.172; 13.D.169.175; 13.D.169.240; 13.D.169.244; 13.D.172.228; 13.D.172.229; 13.D.172.230; 13.D.172.231; 13.D.172.236; 13.D.172.237; 13.D.172.238; 13.D.172.239; 13.D.172.154; 13.D.172.157; 13.D.172.166; 13.D.172.169; 13.D.172.172; 13.D.172.175; 13.D.172.240; 13.D.172.244; 13.D.175.228; 13.D.175.229; 13.D.175.230; 13.D.175.231; 13.D.175.236; 13.D.175.237; 13.D.175.238; 13.D.175.239; 13.D.175.154; 13.D.175.157; 13.D.175.166; 13.D.175.169; 13.D.175.172; 13.D.175.175; 13.D.175.240; 13.D.175.244; 13.D.240.228; 13.D.240.229; 13.D.240.230; 13.D.240.231; 13.D.240.236; 13.D.240.237; 13.D.240.238; 13.D.240.239; 13.D.240.154; 13.D.240.157; 13.D.240.166; 13.D.240.169; 13.D.240.172; 13.D.240.175; 13.D.240.240; 13.D.240.244; 13.D.244.228; 13.D.244.229; 13.D.244.230; 13.D.244.231; 13.D.244.236; 13.D.244.237; 13.D.244.238; 13.D.244.239; 13.D.244.154; 13.D.244.157; 13.D.244.166; 13.D.244.169; 13.D.244.172; 13.D.244.175; 13.D.244.240; 13.D.244.244;

Prodrugs of 13.AB

13.AB.228.228; 13.AB.228.229; 13.AB.228.230; 13.AB.228.231; 13.AB.228.236; 13AB.228.237; 13.AB.228.238; 13.AB.228.239; 13.AB.228.154; 13.AB.228.157; 13AB.228.166; 13.AB.228.169; 13.AB.228.172; 13.AB.228.175; 13.AB.228.240; 13.AB.228.244; 13.AB.229.228; 13.AB.229.229; 13.AB.229.230; 13.AB.229.231; 13.AB.229.236; 13.AB.229.237; 13.AB.229.238; 13.AB.229.239; 13.AB.229.154; 13.AB.229.157; 13.AB.229.166; 13.AB.229.169; 13.AB.229.172; 13.AB.229.175; 13.AB.229.240; 13.AB.229.244; 13.AB.230.228; 13.AB.230.229; 13.AB.23Q.230; 13AB.230.231; 13.AB.230.236; 13.AB.230.237; 13.AB.230.238; 13.AB.230.239; 13.AB.230.154; 13.AB.230.157; 13.AB.230.166; 13.AB.230.169; 13.AB.230.172; 13.AB.230.175; 13.AB.230.240; 13.AB.230.244; 13.AB.231.228; 13.AB.231.229; 13.AB.231.230; 13.AB.231.231; 13.AB.231.236; 13.AB.231.237; 13.AB.231.238; 13.AB.231.239; 13.AB.231.154; 13.AB.231.157; 13.AB.231.166; 13.AB.231.169; 13.AB.231.172; 13.AB.231.175; 13.AB.231.240; 13.AB.231.244; 13.AB.236.228; 13.AB.236.229; 13 AB.236.230; 13.AB.236.231; 13.AB.236.236; 13.AB.236.237; 13.AB.236.238; 13.AB.236.239; 13.AB.236.154; 13.AB.236.157; 13.AB.236.166; 13.AB.236.169; 13.AB.236.172; 13.AB.236.175; 13.AB.236.240; 13.AB.236.244; 13.AB.237.228; 13.AB.237.229; 13.AB.237.230; 13.AB.237.231; 13.AB.237.236; 13.AB.237.237; 13.AB.237.238; 13.AB.237.239; 13.AB.237.154; 13.AB.237.157; 13.AB.237.166; 13.AB.237.169; 13.AB.237.172; 13.AB.237.175; 13.AB.237.240; 13.AB.237.244; 13.AB.238.228; 13.AB.238.229; 13.AB.238.230; 13.AB.238.231; 13.AB.238.236; 13.AB.238.237; 13.AB.238.238; 13.AB.238.239; 13.AB.238.154; 13.AB.238.157; 13.AB.238.166; 13.AB.238.169; 13. AB .238.172; 13.AB.238.175; 13.AB.238.240; 13.AB.238.244; 13.AB.239.228; 13.AB.239.229; 13.AB.239.230; 13.AB.239.231; 13.AB.239.236; 13. AB.239.237; 13.AB.239.238; 13.AB.239.239; 13.AB.239.154; 13. AB.239.157; 13.AB.239.166; 13.AB.239.169; 13.AB.239.172; 13.AB.239.175; 13.AB.239.240; 13. AB.239.244; 13.AB.154.228; 13.AB.154.229; 13.AB.154.230; 13.AB.154.231; 13.AB.154.236; 13.AB.154.237; 13.AB.154.238; 13.AB.154.239; 13.AB.154.154; 13.AB.154.157; 13.AB.154.166; 13.AB.154.169; 13.AB.154.172; 13.AB.154.175; 13.AB.154.240; 13.AB.154.244; 13.AB.157.228; 13.AB.157.229; 13.AB.157.230; 13.AB.157.231; 13.AB.157.236; 13.AB.157.237; 13.AB.157.238; 13.AB.157.239; 13.AB.157.154; 13.AB.157.157; 13.AB.157.166; 13.AB.157.169; 13.AB.157.172; 13.AB.157.175; 13.AB.157.240; 13.AB.157.244; 13.AB.166.228; 13.AB.166.229; 13.AB.166.230; 13.AB.166.231; 13.AB.166.236; 13.AB.166.237; 13.AB.166.238; 13.AB.166.239; 13.AB.166.154; 13.AB.166.157; 13.AB.166.166; 13.AB.166.169; 13.AB.166.172; 13.AB.166.175; 13.AB.166.240; 13.AB.166.244; 13.AB.169.228; 13.AB.169.229; 13.AB.169.230; 13.AB.169.231; 13.AB.169.236; 13.AB.169.237; 13.AB.169.238; 13.AB.169.239; 13.AB.169.154; 13.AB.169.157; 13.AB.169.166; 13.AB.169.169; 13.AB.169.172; 13.AB.169.175; 13.AB.169.240; 13.AB.169.244; 13.AB.172.228; 13.AB.172.229; 13.AB.172.230; 13.AB.172.231; 13.AB.172.236; 13.AB.172.237; 13.AB.172.238; 13.AB.172.239; 13.AB.172.154; 13.AB.172.157; 13.AB.172.166; 13.AB.172.169; 13.AB.172.172; 13.AB.172.175; 13.AB.172.240; 13.AB.172.244; 13.AB.175.228; 13.AB.175.229; 13.AB.175.230; 13.AB.175.231; 13.AB.175.236; 13.AB.175.237; 13.AB.175.238; 13.AB.175.239; 13.AB.175.154; 13.AB.175.157; 13.AB.175.166; 13.AB.175.169; 13.AB.175.172; 13.AB.175.175; 13.AB.175.240; 13.AB.175.244; 13.AB.240.228; 13.AB.240.229; 13.AB.240.230; 13.AB.240.231; 13.AB.240.236; 13.AB.240.237; 13.AB.240.238; 13.AB.240.239; 13.AB.240.154; 13.AB.240.157; 13.AB.240.166; 13.AB.240.169; 13.AB.240.172; 13.AB.240.175; 13.AB.240.240; 13.AB.240.244; 13.AB.244.228; 13.AB.244.229; 13.AB.244.230; 13.AB.244.231; 13.AB.244.236; 13.AB.244.237; 13.AB.244.238; 13-AB.244.239; 13.AB.244.154; 13.AB.244.157; 13.AB.244.166; 13.AB.244.169; 13.AB.244.172; 13.AB.244.175; 13.AB.244.240; 13.AB.244.244;

Prodrugs of 13.BI

13.BI.228.228; 13.BI.228.229; 13.BI.228.230; 13.BI.228.231; 13.BI.228.236; 13.BI.228.237; 13.BL228.238; 13.BI.228.239; 13.BI.228.154; 13.BI.228.157; 13.BI.228.166; 13.BI.228.169; 13.BI.228.172; 13.BI.228.175; 13.BI.228.240; 13.BI.228.244; 13.BI.229.228; 13.BI.229.229; 13.BI.229.230; 13.BI.229.231; 13.BI.229.236; 13.BI.229.237; 13.BI.229.238; 13.BI.229.239; 13.BI.229.154; 13.BI.229.157; 13.BI.229.166; 13.BI.229.169; 13.BI.229.172; 13.BI.229.175; 13.BI.229.240; 13.BI.229.244; 13.BI.230.228; 13.BI.230.229; 13.BI.230.230; 13.BI.230.231; 13.BI.230.236; 13.BI.230.237; 13.BI.230.238; 13.BI.230.239; 13.BI.230.154; 13.BI.230.157; 13.BL230.166; 13.BI.230.169; 13.BI.230.172; 13.BI.230.175; 13.BI.230.240; 13.BI.230.244; 13.BI.231.228; 13.BI.231.229; 13.BI.231.230; 13.BI.231.231; 13.BI.231.236; 13.BI.231.237; 13.BI.231.238; 13.BI.231.239; 13.BI.231.154; 13.BI.231.157; 13.BI.231.166; 13.BI.231.169; 13.BI.231.172; 13.BI.231.175; 13.BI.231.240; 13.BI.231.244; 13.BI.236.228; 13.BI.236.229; 13.BI.236.230; 13.BI.236.231; 13.BI.236.236; 13.BI.236.237; 13.BI.236.238; 13.BI.236.239; 13.BI.236.154; 13.BI.236.157; 13.BI.236.166; 13.BI.236.169; 13.BI.236.172; 13.BI.236.175; 13.BI.236.240; 13.BI.236.244; 13.BI.237.228; 13.BI.237.229; 13.BI.237.230; 13.BI.237.231; 13.BI.237.236; 13.BI.237.237; 13.BI.237.238; 13.BI.237.239; 13.BI.237.154; 13.BI.237.157; 13.BL237.166; 13.BI.237.169; 13.BI.237.172; 13.BI.237.175; 13.BI.237.240; 13.BI.237.244; 13.BI.238.228; 13.BI.238.229; 13.BI.238.230; 13.BI.238.231; 13.BI.238.236; 13.BI.238.237; 13.BI.238.238; 13.BI.238.239; 13.BI.238.154; 13.BL238.157; 13.BI.238.166; 13.BI.238.169; 13.BI.238.172; 13.BI.238.175; 13.BI.238.240; 13.BI.238.244; 13.BI.239.228; 13.BI.239.229; 13.BI.239.230; 13.BI.239.231; 13.BI.239.236; 13.BI.239.237; 13.BI.239.238; 13.BI.239.239; 13.BI.239.154; 13.BI.239.157; 13.BI.239.166; 13.BI.239.169; 13.BI.239.172; 13.BI.239.175; 13.BI.239.240; 13.BI.239.244; 13.BI.154.228; 13.BI.154.229; 13.BI.154.230; 13.BI.154.231; 13.BI.154.236; 13.BI.154.237; 13.BI.154.238; 13.BI.154.239; 13.BI.154.154; 13.BI.154.157; 13.BI.154.166; 13.BI.154.169; 13.BI.154.172; 13.BI.154.175; 13.BI.154.240; 13.BI.154.244; 13.BI.157.228; 13.BI.157.229; 13.BI.157.230; 13.BI.157.231; 13.BI.157.236; 13.BI.157.237; 13.BL157.238; 13.BI.157.239; 13.BI.157.154; 13.BI.157.157; 13.BI.157.166; 13.BI.157.169; 13.BI.157.172; 13.BI.157.175; 13.BI.157.240; 13.BI.157.244; 13.BI.166.228; 13.BI.166.229; 13.BI.166.23Q; 13.BI.166.231; 13.BI.166.236; 13.BI.166.237; 13.BI.166.238; 13.BI.166.239; 13.BI.166.154; 13.BI.166.157; 13.BI.166.166; 13.BI.166.169; 13.BI.166.172; 13.BI.166.175; 13.BI.166.240; 13.BI.166.244; 13.BI.169.228; 13.BI.169.229; 13.BI.169.230; 13.BI.169.231; 13.BI.169.236; 13.BI.169.237; 13.BI.169.238; 13.BI.169.239; 13.BI.169.154; 13.BI.169.157; 13.BI.169.166; 13.BI.169.169; 13.BI.169.172; 13.BI.169.175; 13.BI.169.240; 13.BI.169.244; 13.BI.172.228; 13.BI.172.229; 13.BI.172.230; 13.BL172.231; 13.BI.172.236; 13.BI.172.237; 13.BI.172.238; 13.BI.172.239; 13.BI.172.154; 13.BI.172.157; 13.BI.172.166; 13.BI.172.169; 13.BI.172.172; 13.BI.172.175; 13.BI.172.240; 13.BI.172.244; 13.BI.175.228; 13.BI.175.229; 13.BI.175.230; 13.BI.175.231; 13.BI.175.236; 13.BI.175.237; 13.BI.175.238; 13.BI.175.239; 13.BI.175.154; 13.BI.175.157; 13.BI.175.166; 13.BI.175.169; 13.BI.175.172; 13.BI.175.175; 13.BI.175.240; 13.BI.175.244; 13.BL240.228; 13.BI.240.229; 13.BI.240.230; 13.BI.240.231; 13.BI.240.236; 13.BI.240.237; 13.BI.240.238; 13.BI.240.239; 13.BI.240.154; 13.BI.240.157; 13.BI.240.166; 13.BI.240.169; 13.BI.240.172; 13.BI.240.175; 13.BI.240.240; 13.BI.240.244; 13.BI.244.228; 13.BI.244.229; 13.BI.244.230; 13.BI.244.231; 13.BL244.236; 13.BI.244.237; 13.BI.244.238; 13.BI.244.239; 13.BI.244.154; 13.BI.244.157; 13.BI.244.166; 13.BL244.169; 13.BI.244.172; 13.BI.244.175; 13.BI.244.240; 13.BI.244.244;

Prodrugs of 13.1

13.1.228.228; 13.1.228.229; 13.1.228.230; 13.1.228.231; 13.1.228.236; 13.1.228.237; 13.1.228.238; 13.1.228.239; 13.1.228.154; 13.1.228.157; 13.1.228.166; 13.1.228.169; 13.1.228.172; 13.1.228.175; 13.1.228.240; 13.1.228.244; 13.1.229.228; 13.1.229.229; 13.1.229.230; 13.1.229.231; 13.1.229.236; 13.1.229.237; 13.1.229.238; 13.1.229.239; 13.1.229.154; 13.1.229.157; 13.1.229.166; 13.1.229.169; 13.1.229.172; 13.1.229.175; 13.1.229.240; 13.1.229.244; 13.1.230.228; 13.1.230.229; 13.1.230.230; 13.1.230.231; 13.1.230.236; 13.1.230.237; 13.1.230-238; 13.1.230.239; 13.1.230.154; 13.1.230.157; 13.1.230.166; 13.1.230.169; 13.1.230.172; 13.1.230.175; 13.1.230.240; 13.1.230.244; 13.1.231.228; 13.1.231.229; 13.1.231.230; 13.1.231.231; 13.1.231.236; 13-1.231.237; 13.1.231.238; 13.1.231.239; 13.1.231.154; 13.1.231.157; 13.1.231.166; 13.1.231.169; 13.1.231.172; 13.1.231.175; 13.1.231.240; 13.1.231.244; 13.1.236.228; 13.1.236.229; 13.1.236.230; 13.1.236.231; 13.1.236-236; 13.1.236.237; 13.1.236.238; 13.1.236.239; 13.1.236.154; 13.1.236.157; 13.1.236.166; 13.1.236.169; 13.1.236.172; 13.1.236.175; 13.1.236.240; 13.1.236-244; 13.1.237.228; 13.1.237.229; 13.1.237.230; 13.1.237.231; 13.1.237.236; 13.1.237.237; 13.1.237.238; 13.1.237.239; 13.1.237.154; 13.1.237.157; 13.1.237.166; 13.1.237.169; 13.1.237.172; 13.1.237.175; 13.1.237.240; 13.1.237.244; 13.1.238.228; 13.1.238.229; 13.1.238.230; 13.1.238.231; 13.1.238.236; 13.1.238.237; 13.1.238.238; 13.1.238.239; 13.1.238.154; 13.1.238.157; 13.1.238.166; 13.1.238.169; 13.1.238.172; 13-1-238.175; 13.1.238.240; 13.1.238.244; 13.1.239.228; 13.1.239.229; 13.1.239.230; 13.1.239.231; 13.1.239.236; 13.1.239.237; 13.1.239.238; 13.1.239.239; 13.1.239.154; 13.1.239.157; 13.1.239.166; 13.1.239.169; 13.1.239.172; 13.1.239.175; 13.1.239.240; 13.1.239.244; 13.1.154.228; 13.1.154.229; 13.1.154.230; 13.1.154.231; 13.1.154.236; 13.1.154.237; 13.1.154.238; 13.1.154.239; 13.1.154.154; 13.1.154.157; 13.1.154.166; 13.1.154.169; 13.1.154.172; 13.1.154.175; 13.1.154.240; 13.1.154.244; 13.1.157.228; 13.1.157.229; 13.1.157.230; 13.1.157.231; 13.1.157.236; 13.1.157.237; 13.1.157.238; 13.1.157.239; 13.1.157.154; 13.1.157.157; 13.1.157.166; 13.1.157.169; 13.1.157.172; 13.1.157.175; ,13.1.157.240; 13.1.157.244; 13.1.166.228; 13.1.166.229; 13.1.166.230; 13.1.166.231; 13.1.166.236; 13.1.166.237; 13.1.166.238; 13.1.166.239; 13.1.166.154; 13.1.166.157; 13.1.166-166; 13.1.166.169; 13.1.166.172; 13.1.166.175; 13.1.166.240; 13.1.166.244; 13.1.169.228; 13.1.169.229; 13.1.169.230; 13.1.169.231; 13.1.169.236; 13.1.169.237; 13.1.169.238; 13.1.169.239; 13.1.169.154; 13.1.169.157; 13.1.169.166; 13.1.169.169; 13.1.169.172; 13.1.169.175; 13.1.169.240; 13.1.169.244; 13.1.172.228; 13.1.172.229; 13.1.172.230; 13.1.172.231; 13.1.172.236; 13.1.172.237; 13.1.172.238; 13.1.172.239; 13.1.172.154; 13.1.172.157; 13.1.172.166; 13.1.172.169; 13.1.172.172; 13.1.172.175; 13.1.172.240; 13.1.172.244; 13.1.175.228; 13.1.175.229; 13.1.175.230; 13.1.175.231; 13.1.175.236; 13.1.175.237; 13.1.175.238; 13.1.175.239; 13.1.175.154; 13.1.175.157; 13.1.175.166; 13.1.175.169; 13.1.175.172; 13.1.175.175; 13.1.175.240; 13.1.175.244; 13.1.240.228; 13.1.240.229; 13.1.240.230; 13.1.240.231; 13.1.240.236; 13.1.240.237; 13.1.240.238; 13.1.240.239; 13.1.240.154; 13.1.240.157; 13.1.240.166; 13.1.240.169; 13.1.240.172; 13.1.240.175; 13.1.240.240; 13.1.240.244; 13.1.244.228; 13.1.244.229; 13.1.244.230; 13.1.244.231; 13.1.244.236; 13.1.244.237; 13.1.244.238; 13.1.244.239; 13.1.244.154; 13.1.244.157; 13.1.244.166; 13.1.244.169; 13.1.244.172; 13.1.244.175; 13.1.244.240; 13.1.244.244;

Prodrugs of 13 J

13J.228.228; 13.J.228.229; 13.J.228.230; 13.J.228.231; 13.J.228.236; 13.J.228.237; 13.J.228.238; 13.J.228.239; 13.J.228.154; 13.J.228.157; 13.J.228.166; 13.J.228.169; 13.J.228.172; 13.J.228.175; 13.J.228.240; 13.J.228.244; 13.J.229.228; 13.J.229.229; 13.J.229.230; 13J.229.231; 13J.229.236; 13J.229.237; 13J.229.238; 13J.229.239; 13J.229.154; 13J.229.157; 13J.229.166; 13J.229.169; 13J.229.172; 13J.229.175; 13J.229.240; 13J.229.244; 13J.230.228; 13J.230.229; 13J.230.230; 13J.230.231; 13J.230.236; 13.J.230.237; 13J.230.238; 13J.230.239; 13J.230.154; 13J.230.157; 13J.230.166; 13J.230.169; 13J.230.172; 13J.230.175; 13J.23Q.240; 13J.230.244; 13J.231.228; 13J.231.229; 13J.231.230; 13J.231.231; 13J.231.236; 13J.231.237; 13J.231.238; 13J.231.239; 13J.231.154; 13J.231.157; 13J.231.166; 13J.231.169; 13J.231.172; 13J.231.175; 13J.231.240; 13J.231.244; 13J.236.228; 13J.236.229; 13J.236.230; 13J.236.231; 13J.236.236; 13J.236.237; 13J.236.238; 13J.236.239; 13J.236.154; 13J.236.157; 13J.236.166; 13.J.236.169; 13J.236.172; 13J.236.175; 13J.236.240; 13J.236.244; 13J.237.228; 13J.237.229; 13J.237.230; 13J.237.231; 13J.237.236; 13J.237.237; 13J.237.238; 13.J.237.239; 13J.237.154; 13J.237.157; 13J.237.166; 13.J.237.169; 13J.237.172; 13J.237.175; 13J.237.240; 13J.237.244; 13J.238.228; 13J.238.229; 13J.238.230; 13J.238.231; 13J.238.236; 13J.238.237; 13J.238.238; 13J.238.239; 13J.238.154; 13J.238.157; 13J.238.166; 13J.238.169; 13J.238.172; 13.J.238.175; 13J.238.240; 13J.238.244; 13J.239.228; 13J.239.229; 13J.239.230; 13J.239.231; 13J.239.236; 13J.239.237; 13J.239.238; 13J.239.239; 13J.239.154; 13J.239.157; 13J.239.166; 13J.239.169; 13J.239.172; 13J.239.175; 13J.239.240; 13J.239.244; 13J.154.228; 13J.154.229; 13J.154.230; 13J.154.231; 13J.154.236; 13J.154.237; 13J.154.238; 13J.154.239; 13J.154.154; 13J.154.157; 13J.154.166; 13J.154.169; 13J.154.172; 13J.154.175; 13J.154.240; 13J.154.244; 13J.157.228; 13J.157.229; 13.J.157.230; 13J.157.231; 13J.157.236; 13J.157.237; 13J.157.238; 13J.157.239; 13J.157.154; 13J.157.157; 13J.157.166; 13J.157.169; 13J.157.172; 13J.157.175; 13.J.157.24Q; 13J.157.244; 13J.166.228; 13J.166.229; 13J.166.230; 13J.166.231; 13J.166.236; 13J.166.237; 13J.166.238; 13.J.166.239; 13J.166.154; 13J.166.157; 13J.166.166; 13J.166.169; 13J.166.172; 13J.166.175; 13J.166.240; 13.J.166.244; 13J.169.228; 13J.169.229; 13J.169.230; 13J.169.231; 13J.169.236; 13J.169.237; 13J.169.238; 13J.169.239; 13J.169.154; 13J.169.157; 13J.169.166; 13J.169.169; 13J.169.172; 13J.169.175; 13J.169.240; 13J.169.244; 13J.172.228; 13J.172.229; 13J.172.230; 13J.172.231; 13J.172.236; 13J.172.237; 13J.172.238; 13.J.172.239; 13J.172.154; 13J.172.157; 13J.172.166; 13J.172.169; 13J.172.172; 13J.172.175; 13J.172.240; 13J.172.244; 13J.175.228; 13J.175.229; 13J.175.230; 13J.175.231; 13J.175.236; 13.J.175.237; 13J.175.238; 13J.175.239; 13J.175.154; 13.J.175.157; 13J.175.166; 13J.175.169; 13J.175.172; 13J.175.175; 13J.175.240; 13J.175.244; 13J.240.228; 13J.240.229; 13J.240.230; 13J.240.231; 13J.240.236; 13J.240.237; 13J.240.238; 13J.240.239; 13J.240.154; 13.J.240.157; 13J.240.166; 13J.240.169; 13J.240.172; 13J.240.175; 13.J.240.240; 13J.240.244; 13.J.244.228; 13.J.244.229; 13J.244.230; 13J.244.231; 13J.244.236; 13J.244.237; 13J.244.238; 13J.244.239; 13J.244.154; 13J.244.157; 13J.244.166; 13J.244.169; 13J.244.172; 13J.244.175; 13.J.244.240; 13J.244.244;

Prodrugs of 13.L

13.L.228.228; 13.L.228.229; 13.L.228.230; 13.L.228.231; 13.L.228.236; 13.L.228.237; 13.L.228.238; 13.L.228.239; 13.L.228.154; 13.L.228.157; 13.L.228.166; 13.L.228.169; 13.L.228.172; 13.L.228.175; 13.L.228.240; 13.L.228.244; 13.L.229.228; 13.L.229.229; 13.L.229.230; 13.L.229.231; 13.L.229.236; 13.L.229.237; 13.L.229.238; 13.L.229.239; 13.L.229.154; 13.L.229.157; 13.L.229.166; 13.L.229.169; 13.L.229.172; 13.L.229.175; 13.L.229.240; 13.L.229.244; 13.L.230.228; 13.L.230.229; 13.L.230.230; 13.L.230.231; 13.L.230.236; 13.L.230.237; 13.L.230.238; 13.L.230.239; 13.L.230.154; 13.L.230.157; 13.L.230.166; 13.L.230.169; 13.L.230.172; 13.L.230.175; 13.L.230.240; 13.L.230.244; 13.L.231.228; 13.L.231.229; 13.L.231.230; 13.L.231.231; 13.L.231.236; 13.L.231.237; 13.L.231.238; 13.L.231.239; 13.L.231.154; 13.L.231.157; 13.L.231.166; 13.L.231.169; 13.L.231.172; 13.L.231.175; 13.L.231.240; 13.L.231.244; 13.L.236.228; 13.L.236.229; 13.L.236.230; 13.L.236.231; 13.L.236.236; 13.L.236.237; 13.L.236.238; 13.L.236.239; 13.L.236.154; 13.L.236.157; 13.L.236.166; 13.L.236.169; 13.L.236.172; 13X.236.175; 13.L.236.240; 13.L.236.244; 13.L.237.228; 13.L.237.229; 13.L.237.230; 13.L.237.231; 13.L.237.236; 13.L.237.237; 13.L.237.238; 13.L.237.239; 13.L.237.154; 13.L.237.157; 13.L.237.166; 13.L.237.169; 13.L.237.172; 13.L.237.175; 13.L.237.240; 13.L.237.244; 13.L.238.228; 13.L.238.229; 13.L.238.230; 13.L.238.231; 13.L.238.236; 13.L.238.237; 13.L.238.238; 13.L.238.239; 13.L.238.154; 13.L.238.157; 13.L.238.166; 13.L.238.169; 13.L.238.172; 13.L.238.175; 13.L.238.240; 13.L.238.244; 13.L.239.228; 13.L.239.229; 13.L.239.230; 13.L.239.231; 13.L.239.236; 13.L.239.237; 13.L.239.238; 13.L.239.239; 13X.239.154; 13.L.239.157; 13.L.239.166; 13.L.239.169; 13.L.239.172; 13.L.239.175; 13X.239.240; 13X.239.244; 13X.154.228; 13X.154.229; 13X.154.230; 13X.154.231; 13X.154.236; 13X.154.237; 13X.154.238; 13X.154.239; 13X.154.154; 13X.154.157; 13X.154.166; 13X.154.169; 13X.154.172; 13X.154.175; 13X.154.240; 13X.154.244; 13X.157.228; 13X.157.229; 13X.157.230; 13X.157.231; 13X.157.236; 13X157.237; 13X.157.238; 13X.157.239; 13X.157.154; 13X.157.157; 13X.157.166; 13X.157.169; 13.L.157.172; 13X.157.175; 13X.157.240; 13X.157.244; 13X.166.228; 13X.166.229; 13X.166.230; 13X.166.231; 13X.166.236; 13X.166.237; 13.L.166.238; 13X.166.239; 13X.166.154; 13X.166.157; 13X.166.166; 13X.166.169; 13X.166.172; 13X.166.175; 13X.166.240; 13X.166.244; 13X.169.228; 13X.169.229; 13X.169.230; 13X.169.231; 13X.169.236; 13X.169.237; 13X.169.238; 13X.169.239; 13X.169.154; 13X.169.157; 13X.169.166; 13X.169.169; 13X.169.172; 13X.169.175; 13X.169.240; 13X.169.244; 13X.172.228; 13X.172.229; 13X.172.230; 13X.172.231; 13X.172.236; 13X.172.237; 13X.172.238; 13X.172.239; 13X.172.154; 13X.172.157; 13X.172.166; 13X.172.169; 13X.172.172; 13X.172.175; 13X.172.240; 13X.172.244; 13X.175.228; 13X.175.229; 13X.175.230; 13X.175.231; 13X.175.236; 13X.175.237; 13X.175.238; 13X.175.239; 13X.175.154; 13X175.157; 13X175166; 13X175.169; 13X175172; 13X175175; 13X175.240; 13X175.244; 13X.240.228; 13X.240.229; 13X.240.230; 13X.240.231; 13X.240.236; 13X.240.237; 13X.240.238; 13X.240.239; 13X.240154; 13X.240157; 13.L.240166; 13X.240169; 13X.240172; 13X.240175; 13X.240.240; 13X.240.244; 13X.244.228; 13X.244.229; 13X.244.230; 13X.244.231; 13X.244.236; 13X.244.237; 13X.244.238; 13X.244.239; 13X.244154; 13X.244.157; 13X.244166; 13X.244169; 13X.244172; 13X.244175; 13X.244.240; 13X.244.244;

Prodrugs of 13.0

13.0.228.228; 13.O.228.229; 13.O.228.230; 13.O.228.231; 13.O.228.236; 13.O.228.237; 13.O.228.238; 13.O.228.239; 13.O.228154; 13.O.228157; 13.O.228166; 13.O.228169; 13.O.228172; 13.O.228175; 13.O.228.240; 13.O.228.244; 13.O.229.228; 13.O.229.229; 13.O.229.230; 13.O.229.231; 13.O.229.236; 13.O.229.237; 13.O.229.238; 13.O.229.239; 13.O.229154; 13.O.229.157; 13.O.229.166; 13.O.229.169; 13.O.229.172; 13.O.229.175; 13.O.229.240; 13.O.229.244; 13.O.230.228; 13.O.230.229; 13.O.230.230; 13.O.230.231; 13.O.230.236; 13.O.23Q.237; 13.O.230.238; 13.O.230.239; 13.O.230.154; 13.O.230.157; 13.O.230.166; 13.O.230.169; 13.O.230.172; 13.O.230.175; 13.O.230.240; 13.O.230.244; 13.O.231.228; 13.O.231.229; 13.O.231.230; 13.O.231.231; 13.O.231.236; 13.O.231.237; 13.O.231.238; 13.O.231.239; 13.O.231.154; 13.O.231.157; 13.O.231.166; 13.O.231.169; 13.O.231.172; 13.O.231.175; 13.O.231.240; 13.O.231.244; 13.O.236.228; 13.O.236.229; 13.O.236.230; 13.O.236.231; 13.O.236.236; 13.O.236.237; 13.O.236.238; 13.O.236.239; 13.O.236.154; 13.O.236.157; 13.O.236.166; 13.O.236.169; 13.O.236.172; 13.O.236.175; 13.O.236.240; 13.O.236.244; 13.O.237.228; 13.O.237.229; 13.O.237.230; 13.O.237.231; 13.O.237.236; 13.O.237.237; 13.O.237.238; 13.O.237.239; 13.O.237.154; 13.O.237.157; 13.O.237.166; 13.O.237.169; 13.O.237.172; 13.O.237.175; 13.O.237.240; 13.O.237.244; 13.O.238.228; 13.O.238.229; 13.O.238.230; 13.O.238.231; 13.O.238.236; 13.O.238.237; 13.O.238.238; 13.O.238.239; 13.O.238.154; 13.O.238.157; 13.O.238.166; 13.O.238.169; 13.O.238.172; 13.O.238.175; 13.O.238.240; 13.O.238.244; 13.O.239.228; 13.O.239.229; 13.O.239.230; 13.O.239.231; 13.O.239.236; 13.O.239.237; 13.O.239.238; 13.O.239.239; 13.O.239.154; 13.O.239.157; 13.O.239.166; 13.O.239.169; 13.O-239.172; 13.O.239.175; 13.O.239.240; 13.O.239.244; 13.O.154.228; 13.O.154.229; 13.O.154.230; 13.O.154.231; 13.O.154.236; 13.O.154.237; 13.O.154.238; 13.O.154.239; 13.O.154.154; 13.O.154.157; 13.O.154.166; 13.O.154.169; 13.O.154.172; 13.O.154.175; 13.O.154.240; 13.O.154.244; 13.O.157.228; 13.O.157.229; 13.O.157.230; 13.O.157.231; 13.O.157.236; 13.O.157.237; 13.O.157.238; 13.O.157.239; 13.O.157.154; 13.O.157.157; 13.O.157.166; 13.O.157.169; 13.O.157.172; 13.O.157.175; 13.O.157.240; 13.O.157.244; 13.O.166.228; 13.O.166.229; 13.O.166.230; 13.O.166.231; 13.O.166.236; 13.O.166.237; 13.O.166.238; 13.O.166.239; 13.O.166.154; 13.O.166.157; 13.O.166.166; 13.O.166.169; 13.O.166.172; 13.O.166.175; 13.O.166.240; 13.O.166.244; 13.O.169.228; 13.O.169.229; 13.O.169.230; 13.O.169.231; 13.O.169.236; 13.O.169.237; 13.O.169.238; 13.O.169.239; 13.O.169.154; 13.O.169.157; 13.O.169.166; 13.O.169.169; 13.O.169.172; 13.O.169.175; 13.O.169.240; 13.O.169.244; 13.O.172.228; 13.O.172.229; 13.O.172.230; 13.O.172.231; 13.O.172.236; 13.O.172.237; 13.O.172.238; 13.O.172.239; 13.O.172.154; 13.O.172.157; 13.O.172.166; 13.O.172.169; 13.O.172.172; 13.O.172.175; 13.O.172.240; 13.O.172.244; 13.O.175.228; 13.O.175.229; 13.O.175.230; 13.O.175.231; 13.O.175.236; 13.O.175.237; 13.O.175.238; 13.O.175.239; 13.O.175.154; 13.O.175.157; 13.O.175.166; 13.O.175.169; 13.O.175.172; 13.O.175.175; 13.O.175.240; 13.O.175.244; 13.O.240.228; 13.O.240.229; 13.O.240.230; 13.O.240.231; 13.O.240.236; 13.O.240.237; 13.O.240.238; 13.O.240.239; 13.O.240.154; 13.O.240.157; 13.O.240.166; 13.O.240.169; 13.O.240.172; 13.O.240.175; 13.O.240.240; 13.O.240.244; 13.O.244.228; 13.O.244.229; 13.O.244.230; 13.O.244.231; 13.O.244.236; 13.O.244.237; 13.O.244.238; 13.O.244.239; 13.O.244.154; 13.O.244.157; 13.O.244.166; 13.O.244.169; 13.O.244.172; 13.O.244.175; 13.O.244.240; 13.O.244.244;

Prodrugs of 13.P

13.P.228.228; 13.P.228.229; 13.P.228.230; 13.P.228.231; 13.P.228.236; 13.P.228.237; 13.P.228.238; 13.P.228.239; 13.P.228.154; 13.P.228.157; 13.P.228.166; 13.P.228.169; 13.P.228.172; 13.P.228.175; 13.P.228.240; 13.P.228.244; 13.P.229.228; 13.P.229.229; 13.P.229.230; 13.P.229.231; 13.P.229.236; 13.P.229.237; 13.P.229.238; 13.P.229.239; 13.P.229.154; 13.P.229.157; 13.P.229.166; 13.P.229.169; 13.P.229.172; 13.P.229.175; 13.P.229.240; 13.P.229.244; 13.P.230.228; 13.P.230.229; 13.P.230.230; 13.P.230.231; 13.P.230.236; 13.P.230.237; 13.P.230.238; 13.P.230.239; 13.P.230.154; 13.P.230.157; 13.P.230.166; 13.P.230.169; 13.P.230.172; 13.P.230.175; 13.P.230.240; 13.P.230.244; 13.P.231.228; 13.P.231.229; 13.P.231.230; 13.P.231.231; 13.P.231.236; 13.P.231.237; 13.P.231.238; 13.P.231.239; 13.P.231.154; 13.P.231.157; 13.P.231.166; 13.P.231.169; 13.P.231.172; 13.P.231.175; 13.P.231.240; 13.P.231.244; 13.P.236.228; 13.P.236.229; 13.P.236.230; 13.P.236.231; 13.P.236.236; 13.P.236.237; 13.P.236.238; 13.P.236.239; 13.P.236.154; 13.P.236.157; 13.P.236.166; 13.P.236.169; 13.P.236.172; 13.P.236.175; 13.P.236.240; 13.P.236.244; 13.P.237.228; 13.P.237.229; 13.P.237.230; 13.P.237.231; 13.P.237.236; 13.P.237.237; 13.P.237.238; 13.P.237.239; 13.P.237.154; 13.P.237.157; 13.P.237.166; 13.P.237.169; 13.P.237.172; 13.P.237.175; 13.P.237.240; 13.P.237.244; 13.P.238.228; 13.P.238.229; 13.P.238.230; 13.P.238.231; 13.P.238.236; 13.P.238.237; 13.P.238.238; 13.P.238.239; 13.P.238.154; 13.P.238.157; 13.P.238.166; 13.P.238.169; 13.P.238.172; 13.P.238.175; 13.P.238.240; 13.P.238.244; 13.P.239.228; 13.P.239.229; 13.P.239.230; 13.P.239.231; 13.P.239.236; 13.P.239.237; 13.P.239.238; 13.P.239.239; 13.P.239.154; 13.P.239.157; 13.P.239.166; 13.P.239.169; 13.P.239.172; 13.P.239.175; 13.P.239.240; 13.P.239.244; 13.P.154.228; 13.P.154.229; 13.P.154.230; 13.P.154.231; 13.P.154.236; 13.P.154.237; 13.P.154.238; 13.P.154.239; 13.P.154.154; 13.P.154.157; 13.P.154.166; 13.P.154.169; 13.P.154.172; 13.P.154.175; 13.P.154.240; 13.P.154.244; 13.P.157.228; 13.P.157.229; 13.P.157.230; 13.P.157.231; 13.P.157.236; 13.P.157.237; 13.P.157.238; 13.P.157.239; 13.P.157.154; 13.P.157.157; 13.P.157.166; 13.P.157.169; 13.P.157.172; 13.P.157.175; 13.P.157.240; 13.P.157.244; 13.P.166.228; 13.P.166.229; 13.P.166.230; 13.P.166.231; 13.P.166.236; 13.P.166.237; 13.P.166.238; 13.P.166.239; 13.P.166.154; 13.P.166.157; 13.P.166.166; 13.P.166.169; 13.P.166.172; 13.P.166.175; 13.P.166.240; 13.P.166.244; 13.P.169.228; 13.P.169.229; 13.P.169.230; 13.P.169.231; 13.P.169.236; 13.P.169.237; 13.P.169.238; 13.P.169.239; 13.P.169.154; 13.P.169.157; 13.P.169.166; 13.P.169.169; 13.P.169.172; 13.P.169.175; 13.P.169.240; 13.P.169.244; 13.P.172.228; 13.P.172.229; 13.P.172.230; 13.P.172.231; 13.P.172.236; 13.P.172.237; 13.P.172.238; 13.P.172.239; 13.P.172.154; 13.P.172.157; 13.P.172.166; 13.P.172.169; 13.P.172.172; 13.P.172.175; 13.P.172.240; 13.P.172.244; 13.P.175.228; 13.P.175.229; 13.P.175.230; 13.P.175.231; 13.P.175.236; 13.P.175.237; 13.P.175.238; 13.P.175.239; 13.P.175.154; 13.P.175.157; 13.P.175.166; 13.P.175.169; 13.P.175.172; 13.P.175.175; 13.P.175.240; 13.P.175.244; 13.P.240.228; 13.P.240.229; 13.P.240.230; 13.P.240.231; 13.P.240.236; 13.P.240.237; 13.P.240.238; 13.P.240.239; 13.P.240.154; 13.P.240.157; 13.P.240.166; 13.P.240.169; 13.P.240.172; 13.P.240.175; 13.P.240.240; 13.P.240.244; 13.P.244.228; 13.P.244.229; 13.P.244.230; 13.P.244.231; 13.P.244.236; 13.P.244.237; 13.P.244.238; 13.P.244.239; 13.P.244.154; 13.P.244.157; 13.P.244.166; 13.P.244.169; 13.P.244.172; 13.P.244.175; 13.P.244.240; 13.P.244.244;

Prodrugs of 13.U

13.U.228.228; 13.U.228.229; 13.U.228.230; 13.U.228.231; 13.U.228.236; 13.U.228.237; 13.U.228.238; 13.U.228.239; 13.U.228.154; 13.U.228.157; 13.U.228.166; 13.U.228.169; 13.U.228.172; 13.U.228.175; 13.U.228.240; 13.U.228.244; 13.U.229.228; 13.U.229.229; 13.U.229.230; 13.U.229.231; 13.U.229.236; 13.U.229.237; 13.U.229.238; 13.U.229.239; 13.U.229.154; 13.U.229.157; 13.U.229.166; 13.U.229.169; 13.U.229.172; 13.U.229.175; 13.U.229.240; 13.U.229.244; 13.U.230.228; 13.U.230.229; 13.U.230.230; 13.U.230.231; 13.U.230.236; 13.U.230.237; 13.U.23Q.238; 13.U.230.239; 13.U.230.154; 13.U.230.157; 13.U.230.166; 13.U.230.169; 13.U.230.172; 13.U.230.175; 13.U.230.240; 13.U.230.244; 13.U.231.228; 13.U.231.229; 13.U.231.230; 13.U.231.231; 13.U.231.236; 13.U.231.237; 13.U.231.238; 13.U.231.239; 13.U.231.154; 13.U.231.157; 13.U.231.166; 13.U.231.169; 13.U.231.172; 13.U.231.175; 13.U.231.240; 13.U.231.244; 13.U.236.228; 13.U.236.229; 13.U.236.230; 13.U.236.231; 13.U.236.236; 13.U.236.237; 13.U.236.238; 13.U.236.239; 13.U.236.154; 13.U.236.157; 13.U.236.166; 13.U.236.169; 13.U.236.172; 13.U.236.175; 13.U.236.24Q; 13.U.236.244; 13.U.237.228; 13.U.237.229; 13.U.237.230; 13.U.237.231; 13.U.237.236; 13.U.237.237; 13.U.237.238; 13.U.237.239; 13.U.237.154; 13.U.237.157; 13.U.237.166; 13.U.237.169; 13.U.237.172; 13.U.237.175; 13.U.237.240; 13.U.237.244; 13.U.238.228; 13.U.238.229; 13.U.238.230; 13.U.238.231; 13.U.238.236; 13.U.238.237; 13.U.238.238; 13.U.238.239; 13.U.238.154; 13.U.238.157; 13.U.238.166; 13.U.238.169; 13.U.238.172; 13.U.238.175; 13.U.238.240; 13.U.238.244; 13.U.239.228; 13.U.239.229; 13.U.239.230; 13.U.239.231; 13.U.239.236; 13.U.239.237; 13.U.239.238; 13.U.239.239; 13.U.239.154; 13.U.239.157; 13.U.239.166; 13.U.239.169; 13.U.239.172; 13.U.239.175; 13.U.239.240; 13.U.239.244; 13.U.154.228; 13.U.154.229; 13.U.154.230; 13.U.154.231; 13.U.154.236; 13.U.154.237; 13.U.154.238; 13.U.154.239; 13.U.154.154; 13.U.154.157; 13-U.154.166; 13.U.154.169; 13.U.154.172; 13.U.154.175; 13.U.154.240; 13.U.154.244; 13.U.157.228; 13.U.157.229; 13.U.157.230; 13.U.157.231; 13.U.157.236; 13.U.157.237; 13.U.157.238; 13.U.157.239; 13.U.157.154; 13.U.157.157; 13.U.157.166; 13.U.157.169; 13.U.157.172; 13.U.157.175; 13.U.157.240; 13.U.157.244; 13.U.166.228; 13.U.166.229; 13.U.166.230; 13.U.166.231; 13.U.166.236; 13.U.166.237; 13.U.166.238; 13.U.166.239; 13.U.166.154; 13.U.166.157; 13.U.166.166; 13.U.166.169; 13.U.166.172; 13.U.166.175; 13.U.166.240; 13.U.166.244; 13.U.169.228; 13.U.169.229; 13.U.169.230; 13.U.169.231; 13.U.169.236; 13.U.169.237; 13.U.169.238; 13.U.169.239; 13.U.169.154; 13.U.169.157; 13.U.169.166; 13.U.169.169; 13.U.169.172; 13.U.169.175; 13.U.169.240; 13.U.169.244; 13.U.172.228; 13.U.172.229; 13.U.172.230; 13.U.172.231; 13.U.172.236; 13.U.172.237; 13.U.172.238; 13.U.172.239; 13.U.172.154; 13.U.172.157; 13.U.172.166; 13.U.172.169; 13.U.172.172; 13.U.172.175; 13.U.172.240; 13.U.172.244; 13.U.175.228; 13.U.175.229; 13.U.175.230; 13.U.175.231; 13.U.175.236; 13.U.175.237; 13.U.175.238; 13.U.175.239; 13.U.175.154; 13.U.175.157; 13.U.175.166; 13.U.175.169; 13.U.175.172; 13.U.175.175; 13.U.175.240; 13.U.175.244; 13.U.240.228; 13.U.240.229; 13.U.240.230; 13.U.240.231; 13.U.240.236; 13.U.240.237; 13.U.240.238; 13.U.240.239; 13.U.240.154; 13.U.240.157; 13.U.240.166; 13.U.240.169; 13.U.240.172; 13.U.240.175; 13.U.240.240; 13.U.240.244; 13.U.244.228; 13.U.244.229; 13.U.244.230; 13.U.244.231; 13.U.244.236; 13.U.244.237; 13.U.244.238; 13.U.244.239; 13.U.244.154; 13.U.244.157; 13.U.244.166; 13.U.244.169; 13.U.244.172; 13.U.244.175; 13.U.244.240; 13.U.244.244;

Prodrugs of 13.CD

13.CD.228.228; 13.CD.228.229; 13.CD.228.230; 13.CD.228.231; 13.CD.228.236; 13.CD.228.237; 13.CD.228.238; 13.CD.228.239; 13.CD.228.154; 13.CD.228.157; 13.CD.228.166; 13.CD.228.169; 13.CD.228.172; 13.CD.228.175; 13.CD.228.24Q; 13.CD.228.244; 13.CD.229.228; 13.CD.229.229; 13.CD.229.230; 13.CD.229.231; 13.CD.229.236; 13.CD.229.237; 13.CD.229.238; 13.CD.229.239; 13.CD.229.154; 13.CD.229.157; 13.CD.229.166; 13.CD.229.169; 13.CD.229.172; 13.CD.229.175; 13.CD.229.240; 13.CD.229.244; 13.CD.230.228; 13.CD.230.229; 13.CD.230.230; 13.CD.230.231; 13.CD.230.236; 13.CD.230.237; 13.CD.230.238; 13.CD.230.239; 13.CD.230.154; 13.CD.230.157; 13.CD.230.166; 13.CD.230.169; 13.CD.230.172; 13.CD.230.175; 13.CD.230.240; 13.CD.230.244; 13.CD.231.228; 13.CD.231.229; 13.CD.231.230; 13.CD.231.231; 13.CD.231.236; 13.CD.231.237; 13.CD.231.238; 13.CD.231.239; 13.CD.231.154; 13.CD.231.157; 13.CD.231.166; 13.CD.231.169; 13.CD.231.172; 13.CD.231.175; 13.CD.231.240; 13.CD.231.244; 13.CD.236.228; 13.CD.236.229; 13.CD.236.230; 13.CD.236.231; 13.CD.236.236; 13.CD.236.237; 13.CD.236.238; 13.CD.236.239; 13.CD.236.154; 13.CD.236.157; 13.CD.236.166; 13.CD.236.169; 13.CD.236.172; 13.CD.236.175; 13.CD.236.240; 13.CD.236.244; 13.CD.237.228; 13.CD.237.229; 13.CD.237.230; 13.CD.237.231; 13.CD.237.236; 13.CD.237.237; 13.CD.237.238; 13.CD.237.239; 13.CD.237.154; 13.CD.237.157; 13.CD.237.166; 13.CD.237.169; 13.CD.237.172; 13.CD.237.175; 13.CD.237.240; 13.CD.237.244; 13.CD.238.228; 13.CD.238.229; 13.CD.238.230; 13.CD.238.231; 13.CD.238.236; 13.CD.238.237; 13.CD.238.238; 13.CD.238.239; 13.CD.238.154; 13.CD.238.157; 13.CD.238.166; 13.CD.238.169; 13.CD.238.172; 13.CD.238.175; 13.CD.238.240; 13.CD.238.244; 13.CD.239.228; 13.CD.239.229; 13.CD.239.230; 13.CD.239.231; 13.CD.239.236; 13.CD.239.237; 13.CD.239.238; 13.CD.239.239; 13.CD.239.154; 13.CD.239.157; 13.CD.239.166; 13.CD.239.169; 13.CD.239.172; 13.CD.239.175; 13.CD.239.240; 13.CD.239.244; 13.CD.154.228; 13.CD.154.229; 13.CD.154.230; 13.CD.154.231; 13.CD.154.236; 13.CD.154.237; 13.CD.154.238; 13.CD.154.239; 13.CD.154.154; 13.CD.154.157; 13.CD.154.166; 13.CD.154.169; 13.CD.154.172; 13.CD.154.175; 13.CD.154.240; 13.CD.154.244; 13.CD.157.228; 13.CD.157.229; 13.CD.157.230; 13.CD.157.231; 13.CD.157.236; 13.CD.157.237; 13.CD.157.238; 13.CD.157.239; 13.CD.157.154; 13.CD.157.157; 13.CD.157.166; 13.CD.157.169; 13.CD.157.172; 13.CD.157.175; 13.CD.157.240; 13.CD.157.244; 13.CD.166.228; 13.CD.166.229; 13.CD.166.230; 13.CD.166.231; 13.CD.166.236; 13.CD.166.237; 13.CD.166.238; 13.CD.166.239; 13.CD.166.154; 13.CD.166.157; 13.CD.166.166; 13.CD.166.169; 13. CD.166.172; 13.CD.166.175; 13.CD.166.240; 13.CD.166.244; 13.CD.169.228; 13.CD.169.229; 13.CD.169.230; 13.CD.169.231; 13.CD.169.236; 13.CD.169.237; 13.CD.169.238; 13. CD..169..239; 13.CD.169.154; 13.CD.169.157; 13.CD.169.166; 13.CD.169.169; 13.CD.169.172; 13.CD.169.175; 13.CD.169.240; 13.CD.169.244; 13.CD.172.228; 13.CD.172.229; 13.CD.172.230; 13.CD.172.231; 13. CD.172236; 13. CD.172.237; 13.CD.172.238; 13.CD.172.239; 13.CD.172.154; 13.CD.172.157; 13.CD.172.166; 13.CD.172.169; 13.CD.172.172; 13.CD172.175; 13.CD.172.240; 13.CD.172.244; 13.CD.175.228; 13.CD.175.229; 13.CD.175.230; 13.CD.175.231; 13.CD.175.236; 13.CD.175.237; 13.CD.175.238; 13.CD.175.239; 13.CD.175.154; 13.CD.175.157; 13.CD.175.166; 13.CD.175.169; 13.CD.175.172; 13.CD.175.175; 13.CD.175.240; 13.CD.175.244; 13.CD.240.228; 13.CD.240.229; 13.CD.240.230; 13.CP.240.231; 13.CD.240.236; 13.CD.240.237; 13.CD.240.238; 13.CD.24Q.239; 13.CD.240.154; 13.CD.240.157; 13.CD.240.166; 13.CD.240.169; 13.CD.240.172; 13.CD.240.175; 13.CD.240.240; 13.CD.240.244; 13.CD.244.228; 13.CD.244.229; 13.CD.244.230; 13.CD.244.231; 13.CD.244.236; 13.CD.244.237; 13.CD.244.238; 13.CD.244.239; 13.CD.244.154; 13.CD.244.157; 13.CD.244.166; 13.CD.244.169; 13.CD.244.172; 13.CD.244.175; 13.CD.244.240; 13.CD.244.244;

Prodrugs of 13.EB

13.EB.228.228; 13.EB.228.229; 13.EB.228.230; 13.EB.228.231; 13.EB.228.236; 13.EB.228.237; 13.EB.228.238; 13.EB.228.239; 13.EB.228.154; 13.EB.228.157; 13.EB.228.166; 13.EB.228.169; 13.EB.228.172; 13.EB.228.175; 13.EB.228.240; 13.EB.228.244; 13.EB.229.228; 13.EB.229.229; 13.EB.229.230; 13.EB.229.231; 13.EB.229.236; 13.EB.229.237; 13.EB.229.238; 13.EB.229.239; 13.EB.229.154; 13.EB.229.157; 13.EB.229.166; 13.EB.229.169; 13.EB.229.172; 13.EB.229.175; 13.EB.229.240; 13.EB.229.244; 13.EB.230.228; 13.EB.230.229; 13.EB.230.230; 13.EB.230.231; 13.EB.230.236; 13.EB.23Q.237; 13.EB.230.238; 13.EB.230.239; 13.EB.230.154; 13.EB.230.157; 13.EB.230.166; 13.EB.230.169; 13.EB.230.172; 13.EB.230.175; 13.EB.230.240; 13.EB.23Q.244; 13.EB.231.228; 13.EB.231.229; 13.EB.231.230; 13.EB.231.231; 13.EB.231.236; 13.EB.231.237; 13.EB.231.238; 13.EB.231.239; 13.EB.231.154; 13.EB.231.157; 13.EB.231.166; 13.EB.231.169; 13.EB.231.172; 13.EB.231.175; 13.EB.231.240; 13.EB.231.244; 13.EB.236.228; 13.EB.236.229; 13.EB.236.230; 13.EB.236.231; 13.EB.236.236; 13.EB.236.237; 13.EB.236.238; 13.EB.236.239; 13.EB.236.154; 13.EB.236.157; 13.EB.236.166; 13.EB.236.169; 13.EB.236.172; 13.EB.236.175; 13.EB.236.240; 13.EB.236.244; 13.EB.237.228; 13.EB.237.229; 13.EB.237.230; 13.EB.237.231; 13.EB.237.236; 13.EB.237.237; 13.EB.237.238; 13.EB.237.239; 13.EB.237.154; 13.EB.237.157; 13.EB.237.166; 13.EB.237.169; 13.EB.237.172; 13.EB.237.175; 13.EB.237.240; 13.EB.237.244; 13.EB.238.228; 13.EB.238.229; 13.EB.238.230; 13.EB.238.231; 13.EB.238.236; 13.EB.238.237; 13.EB.238.238; 13.EB.238.239; 13.EB.238.154; 13.EB.238.157; 13.EB.238.166; 13.EB.238.169; 13.EB.238.172; 13.EB.238.175; 13.EB.238.240; 13.EB.238.244; 13.EB.239.228; 13.EB.239.229; 13.EB.239.230; 13.EB.239.231; 13.EB.239.236; 13.EB.239.237; 13.EB.239.238; 13.EB.239.239; 13.EB.239.154; 13.EB.239.157; 13.EB.239.166; 13.EB.239.169; 13.EB.239.172; 13.EB.239.175; 13.EB.239.240; 13.EB.239.244; 13.EB.154.228; 13.EB.154.229; 13.EB.154.230; 13.EB.154.231; 13.EB.154.236; 13.EB.154.237; 13.EB.154.238; 13.EB.154.239; 13.EB.154.154; 13.EB.154.157; 13.EB.154.166; 13.EB.154.169; 13.EB.154.172; 13.EB.154.175; 13.EB.154.240; 13.EB.154.244; 13.EB.157.228; 13.EB.157.229; 13.EB.157.230; 13.EB.157.231; 13.EB.157.236; 13.EB.157.237; 13.EB.157.238; 13.EB.157.239; 13.EB.157.154; 13.EB.157.157; 13.EB.157.166; 13.EB.157.169; 13.EB.157.172; 13.EB.157.175; 13.EB.157.240; 13.EB.157.244; 13.EB.166.228; 13.EB.166.229; 13.EB.166.230; 13.EB.166.231; 13.EB.166.236; 13.EB.166.237; 13.EB.166.238; 13.EB.166.239; 13.EB.166.154; 13.EB.166.157; 13.EB.166.166; 13.EB.166.169; 13.EB.166.172; 13.EB.166.175; 13.EB.166.240; 13.EB.166.244; 13.EB.169.228; 13.EB.169.229; 13.EB.169.230; 13.EB.169.231; 13.EB.169.236; 13.EB.169.237; 13.EB.169.238; 13.EB.169.239; 13.EB.169.154; 13.EB.169.157; 13.EB.169166; 13.EB.169.169; 13. ΕQ.169.172; 13.EB.169.175; 13.EB.169.240; 13.EB.169.244; 13.EB.172.228; 13.EB.172.229; 13.EB.172.230; 13.EB.172.231; 13.EB.172.236; 13.EB.172.237; 13.EB.172.238; 13.EB.172.239; 13.EB.172.154; 13.EB.172.157; 13.EB.172.166; 13.EB.172.169; 13. ΕQ.172.172; 13.EB.172.175; 13.EB.172.240; 13.EB.172.244; 13.EB.175.228; 13.EB.175.229; 13.EB.175.230; 13.EB.175.231; 13.EB.175.236; 13.EB.175.237; 13.EB.175.238; 13.EB.175.239; 13.EB.175.154; 13.EB.175.157; 13.EB.175.166; 13.EB.175.169; 13.EB.175.172; 13.EB.175.175; 13.EB.175.240; 13.EB.175.244; 13.EB.240.228; 13.EB.240.229; 13.EB.240.230; 13.EB.240.231; 13.EB.240.236; 13.EB.240.237; 13.EB.240.238; 13.EB.240.239; 13.EB.240.154; 13.EB.240.157; 13.EB.240.166; 13.EB.240.169; 13.EB.240.172; 13.EB.240.175; 13.EB.240.240; 13.EB.240.244; 13.EB.244.228; 13.EB.244.229; 13.EB.244.230; 13.EB.244.231; 13.EB.244.236; 13.EB.244.237; 13.EB.244.238; 13.EB.244.239; 13.EB.244.154; 13.EB.244.157; 13.EB.244.166; 13.EB.244.169; 13.EB.244.172; 13.EB.244.175; 13.EB.244.240; 13.EB.244.244;

Prodrugs of 14.B

14.B.228.228; 14.B.228.229; 14.B.228.230; 14.B.228.231; 14.B.228.236; 14.B.228.237; 14.B.228.238; 14.B.228.239; 14.B.228.154; 14.B.228.157; 14.B.228.166; 14.B.228.169; 14.B.228.172; 14.B.228.175; 14.B.228.240; 14.B.228.244; 14.B.229.228; 14.B.229.229; 14.B.229.230; 14.B.229.231; 14.B.229.236; 14.B.229.237; 14.B.229.238; 14.B.229.239; 14.B.229.154; 14.B.229.157; 14.B.229.166; 14.B.229.169; 14.B.229.172; 14.B.229.175; 14.B.229.240; 14.B.229.244; 14.B.230.228; 14.B.230.229; 14.B.230.230; 14.B.230.231; 14.B.230.236; 14.B.230.237; 14.B.230.238; 14.B.230.239; 14.B.230.154; 14.B.230.157; 14.B.230.166; 14.B.230.169; 14.B.230.172; 14.B.230.175; 14.B.230.240; 14.B.230.244; 14.B.231.228; 14.B.231.229; 14.B.231.230; 14.B.231.231; 14.B.231.236; 14.B.231.237; 14.B.231.238; 14.B.231.239; 14.B.231.154; 14.B.231.157; 14.B.231.166; 14.B.231.169; 14.B.231.172; 14.B.231.175; 14.B.231.240; 14.B.231.244; 14.B.236.228; 14.B.236.229; 14.B.236.230; 14.B.236.231; 14.B.236.236; 14.B.236.237; 14.B.236.238; 14.B.236.239; 14.B.236.154; 14.B.236.157; 14.B.236.166; 14.B.236.169; 14.B.236.172; 14.B.236.175; 14.B.236.240; 14.B.236.244; 14.B.237.228; 14.B.237.229; 14.B.237.230; 14.B.237.231; 14.B.237.236; 14.B.237.237; 14.B.237.238; 14.B.237.239; 14.B.237.154; 14.B.237.157; 14.B.237.166; 14.B.237.169; 14.B.237.172; 14.B.237.175; 14.B.237.240; 14.B.237.244; 14.B.238.228; 14.B.238.229; 14.B.238.230; 14.B.238.231; 14.B.238.236; 14.B.238.237; 14.B.238.238; 14.B.238.239; 14.B.238.154; 14.B.238.157; 14.B.238.166; 14.B.238.169; 14.B.238.172; 14.B.238.175; 14.B.238.240; 14.B.238.244; 14.B.239.228; 14.B.239.229; 14.B.239.230; 14.B.239.231; 14.B.239.236; 14.B.239.237; 14.B.239.238; 14.B.239.239; 14.B.239.154; 14.B.239.157; 14.B.239.166; 14.B.239.169; 14.B.239.172; 14.B.239.175; 14.B.239.240; 14.B.239.244; 14.B.154.228; 14.B.154.229; 14.B.154.230; 14.B.154.231; 14.B.154.236; 14.B.154.237; 14.B.154.238; 14.B.154.239; 14.B.154.154; 14.B.154.157; 14.B.154.166; 14.B.154.169; 14.B.154.172; 14.B.154.175; 14.B.154.240; 14.B.154.244; 14.B.157.228; 14.B.157.229; 14.B.157.230; 14.B.157.231; 14.B.157.236; 14.B.157.237; 14.B.157.238; 14.B.157.239; 14.B.157.154; 14.B.157.157; 14.B.157.166; 14.B.157.169; 14.B.157.172; 14.B.157.175; 14.B.157.240; 14.B.157.244; 14.B.166.228; 14.B.166.229; 14.B.166.230; 14.B.166.231; 14.B.166.236; 14.B.166.237; 14.B.166.238; 14.B.166.239; 14.B.166.154; 14.B.166.157; 14.B.166.166; 14.B.166.169; 14.B.166.172; 14.B.166.175; 14.B.166.240; 14.B.166.244; 14.B.169.228; 14.B.169.229; 14.B.169.230; 14.B.169.231; 14.B.169.236; 14.B.169.237; 14.B.169.238; 14.B.169.239; 14.B.169.154; 14.B.169.157; 14.B.169.166; 14.B.169.169; 14.B.169.172; 14.B.169.175; 14.B.169.240; 14.B.169.244; 14.B.172.228; 14.B.172.229; 14.B.172.230; 14.B.172.231; 14.B.172.236; 14.B.172.237; 14.B.172.238; 14.B.172.239; 14.B.172.154; 14.B.172.157; 14.B.172.166; 14.B.172.169; 14.B.172.172; 14.B.172.175; 14.B.172.240; 14.B.172.244; 14.B.175.228; 14.B.175.229; 14.B.175.230; 14.B.175.231; 14.B.175.236; 14.B.175.237; 14.B.175.238; 14.B.175.239; 14.B.175.154; 14.B.175.157; 14.B.175.166; 14.B.175.169; 14.B.175.172; U3.175.175; 14.B.175.240; 14.B.175.244; 14.B.240.228; 14.B.240.229; 14.B.240.230; 14.B.240.231; 14.B.240.236; 14.B.240.237; 14.B.240.238; 14.B.240.239; 14.B.240.154; 14.B.240.157; 14.B.240.166; 14.B.240.169; 14.B.24Q.172; 14.B.240.175; 14.B.240.240; 14.B.240.244; 14.B.244.228; 14.B.244.229; 14.B.244.230; 14.B.244.231; 14.B.244.236; 14.B.244.237; 14.B.244.238; 14.B.244.239; 14.B.244.154; 14.B.244.157; 14.B.244.166; 14.B.244.169; 14.B.244.172; 14.B.244.175; 14.B.244.240; 14.B.244.244;

Prodrugs of 14.D

14.D.228.228; 14.D.228.229; 14.D.228.230; 14.D.228.231; 14.D.228.236; 14.D.228.237; 14.D.228.238; 14.D.228.239; 14.D.228.154; 14.D.228.157; 14.D.228.166; 14.D.228.169; 14.D.228.172; 14.D.228.175; 14.D.228.240; 14.D.228.244; 14.D.229.228; 14.D.229.229; 14.D.229.230; 14.D.229.231; 14.D.229.236; 14.D.229.237; 14.P.229.238; 14.D.229.239; 14.D.229.154; 14.D.229.157; 14.D.229.166; 14.D.229.169; 14.D.229.172; 14.D.229.175; 14.D.229.240; 14.D.229.244; 14.D.230.228; 14.D.230.229; 14.D.230.230; 14.D.230.231; 14.D.230.236; 14.D.230.237; 14.D.230.238; 14.D.230.239; 14.D.230.154; 14.D.230.157; 14.D.230.166; 14.D.230.169; 14.D.230.172; 14.D.230.175; 14.D.230.240; 14.D.230.244; 14.D.231.228; 14.D.231.229; 14.D.231.230; 14.D.231.231; 14.D.231.236; 14.D.231.237; 14.D.231.238; 14÷D.231.239; 14.D.231.154; 14.D.231.157; 14.D.231.166; 14.D.231.169; 14.D.231.172; 14.D.231.175; 14.D.231.240; 14.D.231.244; 14.D.236.228; 14.D.236.229; 14.D.236.230; 14.D.236.231; 14.D.236.236; 14.D.236.237; 14.D.236.238; 14.D.236.239; 14.D.236.154; 14.D.236.157; 14.D.236.166; 14.D.236.169; 14.D.236.172; 14.D.236.175; 14.D.236.240; 14.D.236.244; 14.D.237.228; 14.D.237.229; 14.D.237.230; 14.D.237.231; 14.D.237.236; 14.D.237.237; 14.D.237.238; 14.D.237.239; 14.D.237.154; 14.D.237.157; 14.D.237.166; 14.D.237.169; 14.D.237.172; 14.D.237.175; 14.D.237.240; 14.D.237.244; 14.D.238.228; 14.D.238.229; 14.D.238.230; 14.D.238.231; 14.D.238.236; 14.D.238.237; 14.D.238.238; 14.D.238.239; 14.D.238.154; 14.D.238.157; 14.D.238.166; 14.D.238.169; 14.D.238.172; 14.D.238.175; 14.D.238.240; 14.D.238.244; 14.D.239.228; 14.D.239.229; 14.D.239.230; 14.D.239.231; 14.D.239.236; 14.D.239.237; 14.D.239.238; 14.D.239.239; 14.D.239.154; 14.D.239.157; 14.D.239.166; 14.D.239.169; 14.D.239.172; 14.D.239.175; 14.D.239.240; 14.D.239.244; 14.D.154.228; 14.D.154.229; 14.D.154.230; 14.D.154.231; 14.D.154.236; 14.D.154.237; 14.D.154.238; 14.D.154.239; 14.D.154.154; 14.D.154.157; 14.D.154.166; 14.D.154.169; 14.D.154.172; 14.D.154.175; 14.D.154.240; 14.D.154.244; 14.D.157.228; 14.D.157.229; 14.D.157.230; 14.D.157.231; 14.D.157.236; 14.D.157.237; 14.D.157.238; 14.D.157.239; 14.D.157.154; 14.D.157.157; 14.D.157.166; 14.D.157.169; 14.D.157.172; 14.D.157.175; 14.D.157.240; 14.D.157.244; 14.D.166.228; 14.D.166.229; 14.D.166.230; 14.D.166.231; 14.D.166.236; 14.D.166.237; 14.D.166.238; 14.D.166.239; 14.D.166.154; 14.D.166.157; 14.D.166.166; 14.D.166.169; 14.D.166.172; 14.D.166.175; 14.D.166.240; 14.D.166.244; 14.D.169.228; 14.D.169.229; 14.D.169.230; 14.D.169.231; 14.D.169.236; 14.D.169.237; 14.D.169.238; 14.D.169.239; 14.D.169.154; 14.D.169.157; 14.D.169.166; 14.D.169.169; 14.D.169.172; 14.D.169.175; 14.D.169.240; 14.D.169.244; 14.D.172.228; 14.D.172.229; 14.D.172.230; 14.D.172.231; 14.D.172.236; 14.D.172.237; 14.D.172.238; 14.D.172.239; 14.D.172.154; 14.D.172.157; 14.D.172.166; 14.D.172.169; 14.D.172.172; 14.D.172.175; 14.D.172.240; 14.D.172.244; 14.D.175.228; 14.D.175.229; 14.D.175.230; 14.D.175.231; 14.D.175.236; 14.D.175.237; 14.D.175.238; 14.D.175.239; 14.D.175.154; 14.D.175.157; 14.D.175.166; 14.D.175.169; 14.D.175.172; 14.D.175.175; 14.D.175.240; 14.D.175.244; 14.D.240.228; 14.D.240.229; 14.D.240.230; 14.D.240.231; 14.D.240.236; 14.D.240.237; 14.D.240.238; 14.D.240.239; 14.D.240.154; 14.D.240.157; 14.D.240.166; 14.D.240.169; 14.D.240.172; 14.D.240.175; 14.D.240.240; 14.D.240.244; 14.D.244.228; 14.D.244.229; 14.D.244.230; 14.D.244.231; 14.D.244.236; 14.D.244.237; 14.D.244.238; 14.D.244.239; 14.D.244.154; 14.D.244.157; 14.D.244.166; 14.D.244.169; 14.D.244.172; 14.D.244.175; 14.D.244.240; 14.D.244.244;

Prodrugs of 14.AB

14.AB.228.228; 14.AB.228.229; 14.AB.228.230; 14.AB.228.231; 14.AB.228.236; 14.AB.228.237; 14.AB.228.238; 14.AB.228.239; 14.AB.228.154; 14.AB.228.157; 14.AB.228.166; 14.AB.228.169; 14.AB.228.172; 14.AB.228.175; 14.AB.228.240; 14.AB.228.244; 14.AB.229.228; 14.AB.229.229; 14. AB.229.230; 14.AB.229.231; 14.AB.229.236; 14.AB.229.237; 14.AB.229.238; 14.AB.229.239; 14.AB.229.154; 14.AB.229.157; 14.AB.229.166; 14.AB.229.169; 14.AB.229.172; 14.AB.229.175; 14.AB.229.240; 14.AB.229.244; 14.AB.230.228; 14.AB.230.229; 14.AB.230.230; 14.AB.230.231; 14.AB.230.236; 14.AB.230.237; 14.AB.230.238; 14.AB.230.239; 14.AB.230.154; 14.AB.230.157; 14.AB.230.166; 14.AB.230.169; 14.AB.230.172; 14.AB.230.175; 14.AB.230.240; 14.AB.230.244; 14.AB.231.228; 14.AB.231.229; 14.AB.231.230; 14.AB.231.231; 14.AB.231.236; 14. AB .231.237; 14.AB.231.238; 14.AB.231.239; 14.AB.231.154; 14.AB.231.157; 14.AB.231.166; 14.AB.231.169; 14.AB.231.172; 14.AB.231.175; 14.AB.231.240; 14.AB.231.244; 14.AB.236.228; 14.AB.236.229; 14.AB.236.230; 14.AB.236.231; 14.AB.236.236; 14.AB.236.237; 14.AB.236.238; 14.AB.236.239; 14.AB.236.154; 14.AB.236.157; 14.AB.236.166; 14.AB.236.169; 14.AB.236.172; 14.AB.236.175; 14.AB.236.240; 14.AB.236.244; 14.AB.237.228; 14. AB.237.229; 14.AB.237.230; 14.AB.237.231; 14.AB.237.236; 14.AB.237.237; 14.AB.237.238; 14.AB.237.239; 14.AB.237.154; 14.AB.237.157; 14.AB.237.166; 14.AB.237.169; 14.AB.237.172; 14.AB.237.175; 14.AB.237.240; 14.AB.237.244; 14.AB.238.228; 14.AB.238.229; 14.AB.238.230; 14.AB.238.231; 14.AB.238.236; 14.AB.238.237; 14.AB.238.238; 14.AB.238.239; 14.AB.238.154; 14.AB.238.157; 14.AB.238.166; 14.AB.238.169; 14. AB .238.172; 14.AB.238.175; 14.AB.238.240; 14.AB.238.244; 14.AB.239.228; 14.AB.239.229; 14.AB.239.230; 14.AB.239.231; 14.AB.239.236; 14.AB.239.237; 14. AB .239.238; 14.AB.239.239; 14.AB.239.154; 14.AB.239.157; 14.AB.239.166; 14.AB.239.169; 14.AB.239.172; 14.AB.239.175; 14. AB.239.240; 14.AB.239.244; 14.AB.154.228; 14.AB.154.229; 14.AB.154.230; 14.AB.154.231; 14.AB.154.236; 14.AB.154.237; 14.AB.154.238; 14.AB.154.239; 14.AB.154.154; 14.AB.154.157; 14.AB.154.166; 14.AB.154.169; 14.AB.154.172; 14.AB.154.175; 14.AB.154.240; 14.AB.154.244; 14.AB.157.228; 14.AB.157.229; 14.AB.157.230; 14.AB.157.231; 14.AB.157.236; 14.AB.157.237; 14.AB.157.238; 14.AB.157.239; 14.AB.157.154; 14.AB.157.157; 14.AB.157.166; 14.AB.157.169; 14.AB.157.172; 14.AB.157.175; 14.AB.157.240; 14.AB.157.244; 14.AB.166.228; 14.AB.166.229; 14.AB.166.230; 14.AB.166.231; 14.AB.166.236; 14.AB.166.237; 14.AB.166.238; 14.AB.166.239; 14.AB.166.154; 14.AB.166.157; 14.AB.166.166; 14.AB.166.169; 14.AB.166.172; 14.AB.166.175; 14.AB.166.240; 14.AB.166.244; 14.AB.169.228; 14.AB.169.229; 14.AB.169.230; 14.AB.169.231; 14.AB.169.236; 14.AB.169.237; 14.AB.169.238; 14.AB.169.239; 14.AB.169.154; 14.AB.169.157; 14.AB.169.166; 14.AB.169.169; 14.AB.169.172; 14.AB.169.175; 14.AB.169.240; 14.AB.169.244; 14.AB.172.228; 14.AB.172.229; 14.AB.172.230; 14.AB.172.231; 14.AB.172.236; 14.AB.172.237; 14.AB.172.238; 14.AB.172.239; 14.AB.172.154; 14.AB.172.157; 14.AB.172.166; 14.AB.172.169; 14.AB.172.172; 14.AB.172.175; 14.AB.172.240; 14.AB.172.244; 14.AB.175.228; 14.AB.175.229; 14.AB.175.230; 14.AB.175.231; 14.AB.175.236; 14.AB.175.237; 14.AB.175.238; 14.AB.175.239; 14.AB.175.154; 14.AB.175.157; 14.AB.175.166; 14.AB.175.169; 14.AB.175.172; 14.AB.175.175; 14.AB.175.240; 14.AB.175.244; 14.AB.240.228; 14.AB.240.229; 14.AB.240.230; 14.AB.240.231; 14.AB.240.236; 14.AB.240.237; 14.AB.240.238; 14.AB.240.239; 14.AB.240.154; 14.AB.240.157; 14.AB.240.166; 14.AB.240.169; 14.AB.240.172; 14. AB .240.175; 14.AB.240.240; 14.AB.240.244; 14.AB.244.228; 14.AB .244.229; 14.AB.244.230; 14.AB.244.231; 14.AB.244.236; 14.AB.244.237; 14.AB.244.238; 14.AB.244.239; 14.AB.244.154; 14.AB.244.157; 14.AB.244.166; 14.AB.244.169; 14.AB.244.172; 14.AB.244.175; 14.AB.244.240; 14.AB.244.244;

Prodrugs of 14.BI

14.BL228.228; 14.BI.228.229; 14.BI.228.230; 14.BI.228.231; 14.BI.228.236; 14.BI.228.237; 14.BI.228.238; 14.BI.228.239; 14.BI.228.154; 14.BI.228.157; 14.BI.228.166; 14.BI.228.169; 14.BI.228.172; 14.BI.228.175; 14.BI.228.240; 14.BI.228.244; 14.BI.229.228; 14.BI.229.229; 14.BI.229.230; 14.BI.229.231; 14.BI.229.236; 14.BI.229.237; 14.BI.229.238; 14.BI.229.239; 14.BI.229.154; 14.BI.229.157; 14.BI.229.166; 14.BI.229.169; 14.BI.229.172; 14.BI.229.175; 14.BI.229.240; 14.BI.229.244; 14.BI.230.228; 14.BI.230.229; 14.BI.230.230; 14.BL230.231; 14.BI.230.236; 14.BI.230.237; 14.BI.230.238; 14.BI.230.239; 14.BI.230.154; 14.BI.230.157; 14.BI.230.166; 14.BI.230.169; 14.BI.230.172; 14.BI.230.175; 14.BI.230.240; 14.BI.230.244; 14.BI.231.228; 14.BI.231.229; 14.BI.231.230; 14.BI.231.231; 14.BI.231.236; 14.BI.231.237; 14.BI.231.238; 14.BI.231.239; 14.BI.231.154; 14.BI.231.157; 14.BI.231.166; 14.BI.231.169; 14.BI.231.172; 14.BI.231.175; 14.BI.231.240; 14.BI.231.244; 14.BI.236.228; 14.BI.236.229; 14.BI.236.230; 14.BI.236.231; 14.BI.236.236; 14.BI.236.237; 14.BI.236.238; 14.BI.236.239; 14.BI.236.154; 14.BI.236.157; 14.BI.236.166; 14.BI.236.169; 14.BI.236.172; 14.BI.236.175; 14.BI.236.240; 14.BI.236.244; 14.BI.237.228; 14.BI.237.229; 14.BI.237.230; 14.BL237.231; 14.BI.237.236; 14.BI.237.237; 14.BI.237.238; 14.BI.237.239; 14.BI.237.154; 14.BI.237.157; 14.BI.237.166; 14.BI.237.1£9; 14.BI.237.172; 14.BI.237.175; 14.BI.237.240; 14.BL237.244; 14.BI.238.228; 14.BI.238.229; 14.BI.238.230; 14.BI.238.231; 14.BI.238.236; 14.BI.238.237; 14.BI.238.238; 14.BI.238.239; 14.BI.238.154; 14.BI.238.157; 14.BI.238.166; 14.BI.238.169; 14.BI.238.172; 14.BI.238.175; 14.BI.238.240; 14.BI.238.244; 14.BI.239.228; 14.BI.239.229; 14.BI.239.230; 14.BI.239.231; 14.BI.239.236; 14.BI.239.237; 14.BI.239.238; 14.BI.239.239; 14.BI.239.154; 14.BI.239.157; 14.BI.239.166; 14.BL239.169; 14.BI.239.172; 14.BI.239.175; 14.BI.239.240; 14.BI.239.244; 14.BI.154.228; 14.BI.154.229; 14.BI.154.230; 14.BI.154.231; 14.BI.154.236; 14.BI.154.237; 14.BI.154.238; 14.BI.154.239; 14.BI.154.154; 14.BI.154.157; 14.BL154.166; 14.BI.154.169; 14.BI.154.172; 14.BI.154.175; 14.BI.154.240; 14.BI.154.244; 14.BI.157.228; 14.BI.157.229; 14.BI.157.230; 14.BI.157.231; 14.BI.157.236; 14.BI.157.237; 14.BI.157.238; 14.BI.157.239; 14.BI.157.154; 14.BI.157.157; 14.BI.157.166; 14.BI.157.169; 14.BI.157.172; 14.BI.157.175; 14.BI.157.240; 14.BI.157.244; 14.BI.166.228; 14.BI.166.229; 14.BI.166.230; 14.BI.166.231; 14.BI.166.236; 14.BI.166.237; 14.BI.166.238; 14.BI.166.239; 14.BI.166.154; 14.BI.166.157; 14.BI.166.166; 14.BI.166.169; 14.BI.166.172; 14.BI.166.175; 14.BI.166.240; 14.BI.166.244; 14.BI.169.228; 14.BI.169.229; 14.BI.169.230; 14.BI.169.231; 14.BI.169.236; 14.BI.169.237; 14.BI.169.238; 14.BI.169.239; 14.BI.169.154; 14.BI.169.157; 14.BI.169.166; 14.BI.169.169; 14.BI.169.172; 14.BI.169.175; 14.BI.169.240; 14.BI.169.244; 14.BI.172.228; 14.BI.172.229; 14.BI.172.230; 14.BI.172.231; 14.BI.172.236; 14.BI.172.237; 14.BI.172.238; 14.BI.172.239; 14.BI.172.154; 14.BI.172.157; 14.BI.172.166; 14.BI.172.169; 14.BI.172.172; U3l.172.175; 14.BI.172.240; 14.BI.172.244; 14.BI.175.228; 14.BI.175.229; 14.BI.175.230; 14.BI.175.231; 14.BI.175.236; 14.BI.175.237; 14.BI.175.238; 14.BI.175.239; 14.BI.175.154; 14.BI.175.157; 14.BI.175.166; 14.BI.175.169; 14.BI.175.172; 14.BI.175.175; 14.BI.175.240; 14.BI.175.244; 14.BI.240.228; 14.BI.240.229; 14.BI.240.230; 14.BI.240.231; 14.BI.240.236; 14.BI.240.237; 14.BI.240.238; 14.BI.240.239; 14.BI.240.154; 14.BI.240.157; 14.BI.240.166; 14.BI.240.169; 14.BI.240.172; 14.BI.240.175; 14.BI.240.240; 14.BI.240.244; 14.BI.244.228; 14.BI.244.229; 14.BI.244.230; 14.BI.244.231; 14.BI.244.236; 14.BI.244.237; 14.BI.244.238; 14.BI.244.239; 14.BI.244.154; 14.BI.244.157; 14.BI.244.166; 14.BI.244.169; 14.BI.244.172; 14.BI.244.175; 14.BI.244.240; 14.BL244.244;

Prodrugs of 14.1

14.1.228.228; 14.1.228.229; 14.1.228.230; 14.1.228.231; 14.1.228.236; 14.1.228.237; 14.1.228.238; 14.1.228.239; 14.1.228.154; 14.1.228.157; 14.1.228.166; 14.1.228.169; 14.1.228.172; 14.1.228.175; 14.1.228.240; 14.1.228.244; 14.1.229.228; 14.1.229.229; 14.1.229.230; 14.1.229.231; 14.1.229.236; 14.1.229.237; 14.1.229.238; 14.1.229.239; 14.1.229.154; 14.1.229.157; 14.1.229.166; 14.1.229.169; 14.1.229.172; 14.1.229.175; 14.1.229.240; 14.1.229.244; 14.1.230.228; 14.1.230.229; 14.1.230.230; 14.1.230.231; 14.1.230.236; 14.1.230.237; 14.1.230.238; 14.1.230.239; 14.1.230.154; 14.1.230.157; 14.1.230.166; 14.1.230.169; 14.1.230.172; 14.1.230.175; 14.1.230.240; 14.1.230.244; 14.1.231.228; 14.1.231.229; 14.1.231.230; 14.1.231.231; 14.1.231.236; 14.1.231.237; 14.1.231.238; 14.1.231.239; 14.1.231.154; 14.1.231.157; 14.1.231.166; 14.1.231.169; 14.1.231.172; 14.1.231.175; 14.1.231.240; 14.1.231.244; 14.1.236.228; 14.1.236.229; 14.1.236.230; 14.1.236.231; 14.1.236.236; 14.1.236.237; 14.1.236.238; 14.1.236.239; 14.1.236.154; 14.1.236.157; 14.1.236.166; 14.1.236.169; 14.1.236.172; 14.1.236.175; 14.1.236.240; 14.1.236.244; 14.1.237.228; 14.1.237.229; 14.1.237.230; 14.1.237.231; 14.1.237.236; 14.1.237.237; 14.1.237.238; 14.1.237.239; 14.1.237.154; 14.1.237.157; 14.1.237.166; 14.1.237.169; 14.1.237.172; 14.1.237.175; 14.1.237.240; 14.1.237.244; 14.1.238.228; 14.1.238.229; 14.1.238.230; 14.1.238.231; 14.1.238.236; 14.1.238.237; 14.1.238.238; 14.1.238.239; 14.1.238.154; 14.1.238.157; 14.1.238.166; 14.1.238.169; 14.1.238.172; 14.1.238.175; 14.1.238.240; 14.1.238.244; 14.1.239.228; 14.1.239.229; 14.1.239.230; 14.1.239.231; 14.1.239.236; 14.1.239.237; 14.1.239.238; 14.1.239.239; 14.1.239.154; 14.1.239.157; 14.1.239.166; 14.1.239.169; 14.1.239.172; 14.1.239.175; 14.1.239.240; 14.1.239.244; 14.1.154.228; 14.1.154.229; 14.1.154.230; 14.1.154.231; 14.1.154.236; 14.1.154.237; 14.1.154.238; 14.1.154.239; 14.1.154.154; 14.1.154.157; 14.1.154.166; 14.1.154.169; 14.1.154.172; 14.1.154.175; 14.1.154.240; 14.1.154.244; 14.1.157.228; 14.1.157.229; 14.1.157.230; 14.1.157.231; 14.1.157.236; 14.1.157.237; 14.1.157.238; 14.1.157.239; 14.1.157.154; 14.1.157.157; 14.1.157.166; 14.1.157.169; 14.1.157.172; 14.1.157.175; 14.1.157.240; 14.1.157.244; 14.1.166.228; 14.1.166.229; 14.1.166.230; 14.1.166.231; 14.1.166.236; 14.1.166.237; 14.1.166.238; 14.1.166.239; 14.1.166.154; 14.1.166.157; 14.1.166.166; 14.1.166.169; 14.1.166.172; 14.1.166.175; 14.1.166.240; 14.1.166.244; 14.1.169.228; 14.1.169.229; 14.1.169.230; 14.1.169.231; 14.1.169.236; 14.1.169.237; 14.1.169.238; 14.1.169.239; 14.1.169.154; 14.1.169.157; 14.1.169.166; 14.1.169.169; 14.1.169.172; 14.1.169.175; 14.1.169.240; 14.1.169.244; 14.1.172.228; 14.1.172.229; 14.1.172.230; 14.1.172.231; 14.1.172.236; 14.1.172.237; 14.1.172.238; 14.1.172.239; 14.1.172.154; 14.1.172.157; 14.1.172.166; 14.1.172.169; 14.1.172.172; 14.1.172.175; 14.1.172.240; 14.1.172.244; 14.1.175.228; 14.1.175.229; 14.1.175.230; 14.1.175.231; 14.1.175.236; 14.1.175.237; 14.1.175.238; 14.1.175.239; 14.1.175.154; 14.1.175.157; 14.1.175.166; 14.1.175.169; 14.1.175.172; 14.1.175.175; 14.1.175.240; 14.1.175.244; 14.1.240.228; 14.1.240.229; 14.1.240.230; 14.1.240.231; 14.1.240.236; 14.1.240.237; 14.1.240.238; 14.1.240.239; 14.1.240.154; 14.1.240.157; 14.1.240.166; 14.1.240-169; 14.1.240.172; 14.1.240.175; 14.1.240.240; 14.1.240.244; 14.1.244.228; 14.1.244.229; 14.1.244.230; 14.1.244.231; 14.1.244.236; 14.1.244.237; 14.1.244.238; 14.1.244.239; 14.1.244.154; 14.1.244.157; 14.1.244.166; 14.1.244.169; 14.1.244.172; 14.1.244.175; 14.1.244.240; 14.1.244.244;

Prodrugs of 14.T

14.J.228.228; 14.J.228.229; 14.J.228.230; 14J.228.231; 14.J.228.236; 14.J.228.237; 14.J.228.238; 14.J.228.239; 14.J.228.154; 14.J.228.157; 14J.228.166; 14J.228.169; 14J.228.172; 14.J.228.175; 14J.228.240; 14.J.228.244; 14J.229.228; 14J.229.229; 14J.229.230; 14.J.229.231; 14.J.229.236; 14J.229.237; 14J.229.238; 14.J.229.239; 14J.229.154; 14J.229.157; 14J.229.166; 14J.229.169; 14J.229.172; 14J.229.175; 14J.229.240; 14.J.229.244; 14J.230.228; 14.J.230.229; 14J.230.230; 14J.230.231; 14.J.230.236; 14J.230.237; 14J.230.238; 14J.230.239; 14J.230.154; 14J.230.157; 14J.230.166; 14.J.230.169; 14J.230.172; 14J.230.175; 14J.230.240; 14J.230.244; 14J.231.228; 14J.231.229; 14J.231.230; 14J.231.231; 14J.231.236; 14J.231.237; 14J.231.238; 14J.231.239; 14J.231.154; 14J.231.157; 14J.231.166; 14J.231.169; 14J.231.172; 14J.231.175; 14J.231.240; 14J.231.244; 14J.236.228; 14J.236.229; 14J.236.230; 14J.236.231; 14J.236.236; 14J.236.237; 14.J.236.238; 14J.236.239; 14J.236.154; 14J.236.157; 14J.236.166; 14J.236.169; 14J.236.172; 14J.236.175; 14.J.236.240; 14J.236.244; 14J.237.228; 14J.237.229; 14J.237.230; 14J.237.231; 14J.237.236; 14J.237.237; 14J.237.238; 14J.237.239; 14J.237.154; 14J.237.157; 14J.237.166; 14J.237.169; 14J.237.172; 14J.237.175; 14J.237.240; 14J.237.244; 14J.238.228; 14J.238.229; 14J.238.230; 14J.238.231; 14J.238.236; 14J.238.237; 14J.238.238; 14.J.238.239; 14J.238.154; 14J.238.157; 14J.238.166; 14J.238.169; 14.J.238.172; 14J.238.175; 14J.238.240; 14.J.238.244; 14J.239.228; 14J.239.229; 14J.239.230; 14J.239.231; 14J.239.236; 14J.239.237; 14.J.239.238; 14J.239.239; 14J.239.154; 14.J.239.157; 14J.239.166; 14.J.239.169; 14J.239.172; 14.J.239.175; 14.J.239.240; 14J.239.244; 14J.154.228; 14J.154.229; 14J.154.230; 14J.154.231; 14J.154.236; 14.J.154.237; 14J.154.238; 14J.154.239; 14J.154.154; 14.J.154.157; 14.J.154.166; 14J.154.169; 14J.154.172; 14J.154.175; 14J.154.240; 14J.154.244; 14J.157.228; 14J.157.229; 14J.157.230; 14J.157.231; 14J.157.236; 14.J.157.237; 14J.157.238; 14.J.157.239; 14J.157.154; 14J.157.157; 14J.157.166; 14J.157.169; 14J.157.172; 14J.157.175; 14J.157.240; 14J.157.244; 14J.166.228; 14J.166.229; 14J.166.230; 14J.166.231; 14J.166.236; 14J.166.237; 14J.166.238; 14J.166.239; 14 J.166.154; 14J.166.157; 14J.166.166; 14J.166.169; 14J.166.172; 14J.166.175; 14J.166.240; 14J.166.244; 14J.169.228; 14J.169.229; 14J.169.230; 14J.169.231; 14J.169.236; 14J.169.237; 14J.169.238; 14J.169.239; 14J.169.154; 14J.169.157; 14.J.169.166; 14J.169.169; 14J.169.172; 14J.169.175; 14J.169.240; 14J.169.244; 14J.172.228; 14J.172.229; 14J.172.230; 14J.172.231; 14J.172.236; 14J.172.237; 14.J.172.238; 14J.172.239; 14J.172.154; 14J.172.157; 14J.172.166; 14.J.172.169; 14J.172.172; 14.J.172.175; 14J.172.240; 14.J.172.244; 14J.175.228; 14J.175.229; 14J.175.230; 14J.175.231; 14J.175.236; 14J.175.237; 14J.175.238; 14J.175.239; 14J.175.154; 14J.175.157; 14J.175.166; 14.J.175.169; 14J.175.172; 14J.175.175; 14 J.175.240; 14J.175.244; 14.J.240.228; 14J.240.229; 14J.240.230; 14.J.240.231; 14J.240.236; 14J.240.237; 14J.240.238; 14.J.240.239; 14.J.240.154; 14J.240.157; 14J.240.166; 14J.240.169; 14.J.240.172; 14J.240.175; 14J.240.240; 14.J.240.244; 14J.244.228; 14J.244.229; 14J.244.230; 14J.244.231; 14.J.244.236; 14J.244.237; 14.J.244.238; 14.J.244.239; 14.J.244.154; 14.J.244.157; 14.J.244.166; 14.J.244.169; 14.J.244.172; 14.J.244.175; 14.J.244.240; 14.J.244.244;

Prodrugs of 14.L

14.L.228.228; 14.L.228.229; 14.L.228.230; 14.L.228.231; 14.L.228.236; 14.L.228.237; 14.L.228.238; 14.L.228.239; 14.L.228.154; 14.L.228.157; 14.L.228.166; 14.L.228.169; 14.L.228.172; 14.L.228.175; 14.L.228.240; 14.L.228.244; 14.L.229.228; 14.L.229.229; 14.L.229.23Q; 14.L.229.231; 14.L.229.236; 14.L.229.237; 14.L.229.238; 14.L.229.239; 14.L.229.154; 14.L.229.157; 14.L.229.166; 14.L.229.169; 14.L.229.172; 14.L.229.175; 14.L.229.240; 14.L.229.244; 14.L.230.228; 14.L.230.229; 14.L.230.230; 14.L.230.231; 14.L.230.236; 14.L.230.237; 14.L.230.238; 14.L.230.239; 14.L.230.154; 14.L.230.157; 14.L.230.166; 14.L.230.169; 14.L.230.172; 14.L.230.175; 14.L.230.240; 14.L.230.244; 14.L.231.228; 14.L.231.229; 14.L.231.230; 14.L.231.231; 14.L.231.236; 14.L.231.237; 14.L.231.238; 14.L.231.239; 14.L.231.154; 14.L.231.157; 14.L.231.166; 14.L.231.169; 14.L.231.172; 14.L.231.175; 14.L.231.240; 14.L.231.244; 14.L.236.228; 14.L.236.229; 14.L.236.230; 14.L.236.231; 14.L.236.236; 14.L.236.237; 14.L.236.238; 14.L.236.239; 14.L.236.154; 14.L.236.157; 14.L.236.166; 14.L.236.169; 14.L.236.172; 14.L.236.175; 14.L.236.240; 14.L.236.244; 14.L.237.228; 14.L.237.229; 14.L.237.230; 14.L.237.231; 14.L.237.236; 14.L.237.237; 14.L.237.238; 14.L.237.239; 14.L.237.154; 14.L.237.157; 14.L.237.166; 14.L.237.169; 14.L.237.172; 14.L.237.175; 14.L.237.240; 14.L.237.244; 14.L.238.228; 14.L.238.229; 14.L.238.230; 14.L.238.231; 14.L.238.236; 14.L.238.237; 14.L.238.238; 14.L.238.239; 14.L.238.154; 14.L.238.157; 14.L.238.166; 14.L.238.169; 14.L.238.172; 14.L.238.175; 14.L.238.240; 14.L.238.244; 14.L.239.228; 14.L.239.229; 14.L.239.230; 14.L.239.231; 14.L.239.236; 14.L.239.237; 14.L.239.238; 14.L.239.239; 14.L.239.154; 14.L.239.157; 14.L.239.166; 14.L.239.169; 14.L.239.172; 14.L.239.175; 14.L.239.240; 14.L.239.244; 14.L.154.228; 14.L.154.229; 14.L.154.230; 14.L.154.231; 14.L.154.236; 14.L.154.237; 14.L.154.238; 14.L.154.239; 14.L.154.154; 14.L.154.157; 14.L.154.166; 14.L.154.169; 14.L.154.172; 14.L.154.175; 14.L.154.240; 14.L.154.244; 14.L.157.228; 14.L.157.229; 14.L.157.230; 14.L.157.231; 14.L.157.236; 14.L.157.237; 14.L.157.238; 14.L.157.239; 14.L.157.154; 14.L.157.157; 14.L.157.166; 14.L.157.169; 14.L.157.172; 14.L.157.175; 14.L.157.240; 14.L.157.244; 14.L.166.228; 14.L.166.229; 14.L.166.230; 14.L.166.231; 14.L.166.236; 14.L.166.237; 14.L.166.238; 14.L.166.239; 14.L.166.154; 14.L.166.157; 14.L.166.166; 14.L.166.169; 14.L.166.172; 14.L.166.175; 14.L.166.240; 14.L.166.244; 14.L.169.228; 14.L.169.229; 14.L.169.230; 14.L.169.231; 14.L.169.236; 14.L.169.237; 14.L.169.238; 14.L.169.239; 14.L.169.154; 14.L.169.157; 14.L.169.166; 14.L.169.169; 14.L.169.172; 14.L.169.175; 14.L.169.240; 14.L.169.244; 14.L.172.228; 14.L.172.229; 14.L.172.230; 14.L.172.231; 14.L.172.236; 14.L.172.237; 14.L.172.238; 14.L.172.239; 14.L.172.154; 14.L.172.157; 14.L.172.166; 14.L.172.169; 14.L.172.172; 14.L.172.175; 14.L.172.240; 14.L.172.244; 14.L.175.228; 14.L.175.229; 14.L.175.230; 14.L.175.231; 14.L.175.236; 14.L.175.237; 14.L.175.238; 14.L.175.239; 14.L.175.154; 14.L.175.157; 14.L.175.166; 14.L.175.169; 14.L.175.172; 14.L.175.175; 14.L.175.240; 14.L.175.244; 14.L.240.228; 14.L.240.229; 14.L.240.230; 14.L.240.231; 14.L.240.236; 14.L.240.237; 14.L.240.238; 14.L.240.239; 14.L.240.154; 14.L.240.157; 14.L.240.166; 14.L.240.169; 14.L.240172; 14.L.240.175; 14.L.240.240; 14.L.240.244; 14.L.244.228; 14.L.244.229; 14.L.244.230; 14.L.244.231; 14.L.244.236; 14.L.244.237; 14.L.244.238; 14.L.244.239; 14.L.244.154; 14.L.244.157; 14.L.244.166; 14.L.244.169; 14.L.244.172; 14.L.244.175; 14.L.244.240; 14.L.244.244;

Prodrugs of 14.O

14.O.228.228; 14.O.228.229; 14.O.228.230; 14.O.228.231; 14.O.228.236; 14.O.228.237; 14.O.228.238; 14.O.228.239; 14.O.228.154; 14.O.228.157; 14.O.228.166; 14.O.228.169; 14.O.228.172; 14.O.228.175; 14.O.228.240; 14.O.228.244; 14.O.229.228; 14.O.229.229; 14.O.229.230; 14.O.229.231; 14.O.229.236; 14.O.229.237; 14.O.229.238; 14.Q.229.239; 14.O.229.154; 14.O.229.157; 14.O.229.166; 14.O.229.169; 14.O.229.172; 14.O.229.175; 14.O.229.240; 14.O.229.244; 14.O.230.228; 14.O.230.229; 14.O.230.230; 14.O.230.231; 14.O.230.236; 14.O.230.237; 14.O.23Q.238; 14.O.230.239; 14.O.230.154; 14.O.230.157; 14.O.230.166; 14.O.230.169; 14.O.230.172; 14.O.230.175; 14.O.230.240; 14.O.230.244; 14.O.231.228; 14.O.231.229; 14.O.231.230; 14.O.231.231; 14.O.231.236; 14.O.231.237; 14.O.231.238; 14.O.231.239; 14.O.231.154; 14.O.231.157; 14.O.231.166; 14.O.231.169; 14.O.231.172; 14.O.231.175; 14.O.231.240; 14.O.231.244; 14.O.236.228; 14.O.236.229; 14.O.236.230; 14.O.236.231; 14.O.236.236; 14.O.236.237; 14.O.236.238; 14.O.236.239; 14.O.236.154; 14.O.236.157; 14.O.236.166; 14.O.236.169; 14.O.236.172; 14.O.236.175; 14.O.236.240; 14.O.236.244; 14.O.237.228; 14.O.237.229; 14.O.237.230; 14.O.237.231; 14.O.237.236; 14.O.237.237; 14.O.237.238; 14.O.237.239; 14.O.237.154; 14.O.237.157; 14.O.237.166; 14.O.237.169; 14.O.237.172; 14.O.237.175; 14.O.237.240; 14.O.237.244; 14.O-238.228; 14.O.238.229; 14.O.238.230; 14.O.238.231; 14.O.238.236; 14.O.238.237; 14.O.238.238; 14.O.238.239; 14.O.238.154; 14.O.238.157; 14.O.238.166; 14.O.238.169; 14.O.238.172; 14.O.238.175; 14.O.238.240; 14.O.238.244; 14.O.239.228; 14.O.239.229; 14.O.239.230; 14.O.239.231; 14.O.239.236; 14.O.239.237; 14.O.239.238; 14.O.239.239; 14.O.239.154; 14.O.239.157; 14.O.239.166; 14.O.239.169; 14.O.239.172; 14.O.239.175; 14.O.239.240; 14.O.239.244; 14.O.154.228; 14.O.154.229; 14.O.154.230; 14.O.154.231; 14.O.154.236; 14.O.154.237; 14.O.154.238; 14.O.154.239; 14.O.154.154; 14.O.154.157; 14.O.154.166; 14.O.154.169; 14.O.154.172; 14.O.154.175; 14.O.154.240; 14.O.154.244; 14.O.157.228; 14.O.157.229; 14.O.157.230; 14.O.157.231; 14.O.157.236; 14.O.157.237; 14.O.157.238; 14.O.157.239; 14.O.157.154; 14.O.157.157; 14.O.157.166; 14.O.157.169; 14.O.157.172; 14.O.157.175; 14.O.157.240; 14.O.157.244; 14.O.166.228; 14.O.166.229; 14.O.166.230; 14.O.166.231; 14.O.166.236; 14.O.166.237; 14.O.166.238; 14.O.166.239; 14.O.166.154; 14.O.166.157; 14.O.166.166; 14.O.166.169; 14.O.166.172; 14.O.166.175; 14.O.166.240; 14.O.166.244; 14.O.169.228; 14.O.169.229; 14.O.169.230; 14.O.169.231; 14.O.169.236; 14.O.169.237; 14.O.169.238; 14.O.169.239; 14.O.169.154; 14.O.169.157; 14.O.169.166; 14.O.169.169; 14.O.169.172; 14.O.169.175; 14.O.169.240; 14.O.169.244; 14.O.172.228; 14.O.172.229; 14.O.172.230; 14.O.172.231; 14.O.172.236; 14.O.172.237; 14.O.172.238; 14.O.172.239; 14.O.172.154; 14.O.172.157; 14.O.172.166; 14.O.172.169; 14.O.172.172; 14.O.172.175; 14.O.172.240; 14.O.172.244; 14.O.175.228; 14.O.175.229; 14.O.175.230; 14.O.175.231; 14.O.175.236; 14.O.175.237; 14.O.175.238; 14.O.175.239; 14.O.175.154; 14.O.175.157; 14.O.175.166; 14.O.175.169; 14.O.175.172; 14.O.175.175; 14.O.175.240; 14.O.175.244; 14.O.240.228; 14.O.240.229; 14.O.240.230; 14.O.240.231; 14.O.240.236; 14.O.240.237; 14.O.240.238; 14.O.240.239; 14.O.240.154; 14.O.240.157; 14.O.240.166; 14.O.240.169; 14.O.240.172; 14.O.240.175; 14.O.24Q.240; 14.O.240.244; 14.O.244.228; 14.O.244.229; 14.O.244.230; 14.O.244.231; 14.O.244.236; 14.O.244.237; 14.O.244.238; 14.O.244.239; 14.O.244.154; 14.O.244.157; 14.O.244.166; 14.O.244.169; 14.O.244.172; 14.O.244.175; 14.O.244.240; 14.O.244.244;

Prodrugs of 14.P

14.P.228.228; 14.P.228.229; 14.P.228.230; 14.P.228.231; 14.P.228.236; 14.P.228.237; 14.P.228.238; 14.P.228.239; 14.P.228.154; 14.P.228.157; 14.P.228.166; 14.P.228.169; 14.P.228.172; 14.P.228.175; 14.P.228.240; 14.P.228.244; 14.P.229.228; 14.P.229.229; 14.P.229.230; 14.P.229.231; 14.P.229.236; 14.P.229.237; 14.P.229.238; 14.P.229.239; 14.P.229.154; 14.P.229.157; 14.P.229.166; 14.P.229.169; 14.P.229.172; 14.P.229.175; 14.P.229.240; 14.P.229.244; 14.P.230.228; 14.P.230.229; 14.P.230.230; 14.P.230.231; 14.P.230.236; 14.P.230.237; 14.P.230.238; 14.P.230.239; 14.P.230.154; 14.P.230.157; 14.P.230.166; 14.P.230.169; 14.P.230.172; 14.P.230.175; 14.P.230.240; 14.P.230.244; 14.P.231.228; 14.P.231.229; 14.P.231.230; 14.P.231.231; 14.P.231.236; 14.P.231.237; 14.P.231.238;14.P.231.239; 14.P.231.154; 14.P.231.157; 14.P.231.166; 14.P.231.169; 14.P.231.172; 14.P.231.175; 14.P.231.240; 14.P.231.244; 14.P.236.228; 14.P.236.229; 14.P.236.230; 14.P.236.231; 14.P.236.236; 14.P.236.237; 14.P.236.238; 14.P.236.239; 14.P.236.154; 14.P.236.157; 14.P.236.166; 14.P.236.169; 14.P.236.172; 14.P.236.175; 14.P.236.240; 14.P.236.244; 14.P.237.228; 14.P.237.229; 14.P.237.230; 14.P.237.231; 14.P.237.236; 14.P.237.237; 14.P.237.238; 14.P.237.239; 14.P.237.154; 14.P.237.157; 14.P.237.166; 14.P.237.169; 14.P.237.172; 14.P.237.175; 14.P.237.240; 14.P.237.244; 14.P.238.228; 14.P.238.229; 14.P.238.230; 14.P.238.231; 14.P.238.236; 14.P.238.237; 14.P.238.238; 14.P.238.239; 14.P.238.154; 14.P.238.157; 14.P.238.166; 14.P.238.169; 14.P.238.172; 14.P.238.175; 14.P.238.240; 14.P.238.244; 14.P.239.228; 14.P.239.229; 14.P.239.230; 14.P.239.231; 14.P.239.236; 14.P.239.237; 14.P.239.238; 14.P.239.239; 14.P.239.154; 14.P.239.157; 14.P.239.166; 14.P.239.169; 14.P.239.172; 14.P.239.175; 14.P.239.240; 14.P.239.244; 14.P.154.228; 14.P.154.229; 14.P.154.230; 14.P.154.231; 14.P.154.236; 14.P.154.237; 14.P.154.238; 14.P.154.239; 14.P.154.154; 14.P.154.157; 14.P.154.166; 14.P.154.169; 14.P.154.172; 14.P.154.175; 14.P.154.240; 14.P.154.244; 14.P.157.228; 14.P.157.229; 14.P.157.230; 14.P.157.231; 14.P.157.236; 14.P.157.237; 14.P.157.238; 14.P.157.239; 14.P.157.154; 14.P.157.157; 14.P.157.166; 14.P.157.169; 14.P.157.172; 14.P.157.175; 14.P.157.240; 14.P.157.244; 14.P.166.228; 14.P.166.229; 14.P.166.230; 14.P.166.231; 14.P.166.236; 14.P.166.237; 14.P.166.238; 14.P.166.239; 14.P.166.154; 14.P.166.157; 14.P.166.166; 14.P.166.169; 14.P.166.172; 14.P.166.175; 14.P.166.240; 14.P.166.244; 14.P.169.228; 14.P.169.229; 14.P.169.230; 14.P.169.231; 14.P169.236; 14.P.169.237; 14.P.169.238; 14.P.169.239; 14.P.169.154; 14.P.169.157; 14.P.169.166; 14.P.169.169; 14.P.169.172; 14.P.169.175; 14.P.169.240; 14.P.169.244; 14.P.172.228; 14.P.172.229; 14.P.172.230; 14.P.172.231; 14.P.172.236; 14.P.172.237; 14.P.172.238; 14.P.172.239; 14.P.172.154; 14.P.172.157; 14.P.172.166; 14.P.172.169; 14.P.172.172; 14.P.172.175; 14.P.172.240; 14.P.172.244; 14.P.175.228; 14.P.175.229; 14.P.175.230; 14.P.175.231; 14.P.175.236; 14.P.175.237; 14.P.175.238; 14.P.175.239; 14.P.175.154; 14.P.175.157; 14.P.175.166; 14.P.175.169; 14.P.175.172; 14.P.175.175; 14.P.175.240; 14.P.175.244; 14.P.240.228; 14.P.240.229; 14.P.240.230; 14.P.240.231; 14.P.240.236; 14.P.240.237; 14.P.240.238; 14.P.240.239; 14.P.240.154; 14.P.240.157; 14.P.240.166; 14.P.240.169; 14.P.240.172; 14.P.240.175; 14.P.240.240; 14.P.240.244; 14.P.244.228; 14.P.244.229; 14.P.244.230; 14.P.244.231; 14.P.244.236; 14.P.244.237; 14.P.244.238; 14.P.244.239; 14.P.244.154; 14.P.244.157; 14.P.244.166; 14.P.244.169; 14.P.244.172; 14.P.244.175; 14.P.244.240; 14.P.244.244;

Prodrugs of 14.U

14.U.228.228; 14.U.228.229; 14.U.228.230; 14.U.228.231; 14.U.228.236; 14.U.228.237; 14.U.228.238; 14.U.228.239; 14.U.228.154; 14.U.228.157; 14.U.228.166; 14.U.228.169; 14.U.228.172; 14.U.228.175; 14.U.228.240; 14.U.228.244; 14.U.229.228; 14.U.229.229; 14.U.229.230; 14.U.229.231; 14.U.229.236; 14.U.229.237; 14.U.229.238; 14.U.229.239; 14.U.229.154; 14.U.229.157; 14.U.229.166; 14.U.229.169; 14.U.229.172; 14.U.229.175; 14.U.229.240; 14.U.229.244; 14.U.230.228; 14.U.230.229; 14.U.230.230; 14.U.230.231; 14.U.230.236; 14.U.230.237; 14.U.230.238; 14.U.230.239; 14.U.230.154; 14.U.230.157; 14.U.230.166; 14.U.230.169; 14.U.230.172; 14.U.230.175; 14.U.230.24Q; 14.U.230.244; 14.U.231.228; 14.U.231.229; 14.U.231.230; 14.U.231.231; 14.U.231.236; 14.U.231.237; 14.U.231.238; 14.U.231.239; 14.U.231.154; 14.U.231.157; 14.U.231.166; 14.U.231.169; 14.U.231.172; 14.U.231.175; 14.U.231.240; 14.U.231.244; 14.U.236.228; 14.U.236.229; 14.U.236.230; 14.U.236.231; 14.U.236.236; 14.U.236.237; 14.U.236.238; 14.U.236.239; 14.U.236.154; 14.U.236.157; 14.U.236.166; 14.U.236.169; 14.U.236.172; 14.U.236.175; 14.U.236-240; 14.U.236.244; 14.U.237.228; 14.U.237.229; 14.U.237.230; 14.U.237.231; 14.U.237.236; 14.U.237.237; 14.U.237.238; 14.U.237.239; 14.U.237.154; 14.U.237.157; 14.U.237.166; 14.U.237.169; 14.U.237.172; 14.U.237.175; 14.U.237.240; 14.U.237.244; 14.U.238.228; 14.U.238.229; 14.U.238.230; 14.U.238.231; 14.U.238.236; 14.U.238.237; 14.U.238.238; 14.U.238.239; 14.U.238.154; 14.U.238.157; 14.U.238.166; 14.U.238.169; 14.U.238.172; 14.U.238.175; 14.U.238.240; 14.U.238.244; 14.U.239.228; 14.U.239.229; 14.U.239.230; 14.U.239.231; 14.U.239.236; 14.U.239.237; 14.U.239.238; 14.U.239.239; 14.U.239.154; 14.U.239.157; 14.U.239.166; 14.U.239.169; 14.U.239.172; 14.U.239.175; 14.U.239.240; 14.U.239.244; 14.U.154.228; 14.U.154.229; 14.U.154.230; 14.U.154.231; 14.U.154.236; 14.U.154.237; 14.U.154.238; 14.U.154.239; 14.U.154.154; 14.U.154.157; 14.U.154.166; 14.U.154.169; 14.U.154.172; 14.U.154.175; 14.U.154.240; 14.U.154.244; 14.U.157.228; 14.U.157.229; 14.U.157.230; 14.U.157.231; 14.U.157.236; 14.U.157.237; 14.U.157.238; 14.U.157.239; 14.U.157.154; 14.U.157.157; 14.U.157.166; 14.U.157.169; 14.U.157.172; 14.U.157.175; 14.U.157.240; 14.U.157.244; 14.U.166.228; 14.U.166.229; 14.U.166.230; 14.U.166.231; 14.U.166.236; 14.U.166.237; 14.U.166.238; 14.U.166.239; 14.U.166.154; 14.U.166.157; 14.U.166.166; 14.U.166.169; 14.U.166.172; 14.U.166.175; 14.U.166.240; 14.U.166.244; 14.U.169.228; 14.U.169.229; 14.U.169.230; 14.U.169.231; 14.U.169.236; 14.U.169.237; 14.U.169.238; 14.U.169.239; 14.U.169.154; 14.U.169.157; 14.U.169.166; 14.IJ.169.169; 14.U.169.172; 14.U.169.175; 14.U.169.240; 14.U.169.244; UV .172.228; 14.U.172.229; 14.U.172.230; 14.U.172.231; 14.U.172.236; 14.U.172.237; 14.U.172.238; 14.U.172.239; 14.U.172.154; 14.U.172.157; 14.U.172.166; 14.U.172.169; 14.U.172.172; 14.U.172.175; 14.U.172.240; 14.U.172.244; 14.U.175.228; 14.U.175.229; 14.U.175.230; 14.U.175.231; 14.U.175.236; 14.U.175.237; 14.U.175.238; 14.U.175.239; 14.U.175.154; 14.U.175.157; 14.U.175.166; 14.U.175.169; 14.U.175.172; 14.U.175.175; 14.U.175.240; 14.U.175.244; 14.U.240.228; 14.U.240.229; 14.U.240.230; 14.U.240.231; 14.U.240.236; 14.U.240.237; 14.U.240.238; 14.U.240.239; 14.U.24Q.154; 14.U.240.157; 14.U.240.166; 14.U.240.169; 14.U.240.172; 14.U.240.175; 14.U.240.240; 14.U.240.244; 14.U.244.228; 14.U.244.229; 14.U.244.230; 14.U.244.231; 14.U.244.236; 14.U.244.237; 14.U.244.238; 14.U.244.239; 14.U.244.154; 14.U.244.157; 14.U.244.166; 14.U.244.169; 14.U.244.172; 14.U.244.175; 14.U.244.240; 14.U.244.244;

Prodrugs of 14.CD

14.CD.228.228; 14.CD.228.229; 14.CD.228.230; 14.CD.228.231; 14.CD.228.236; 14.CD.228.237; 14.CD.228.238; 14.CD.228.239; 14.CD.228.154; 14.CD.228.157; 14.CD.228.166; 14.CD.228.169; 14.CD.228.172; 14.CD.228.175; 14.CD.228.240; 14.CD.228.244; 14.CD.229.228; 14.CD.229.229; 14.CD.229.230; 14.CD.229.231; 14.CD.229.236; 14.CD.229.237; 14.CD.229.238; 14.CD.229.239; 14.CD.229.154; 14.CD.229.157; 14.CD.229.166; 14.CD.229.169; 14.CD.229.172; 14.CD.229.175; 14.CD.229.240; 14.CD.229.244; 14.CD.230.228; 14.CD.230.229; 14.CD.230.230; 14.CD.230.231; 14.CD.230.236; 14.CD.230.237; 14.CD.230.238; 14.CD.230.239; 14.CD.230.154; 14.CD.230.157; 14.CD.230.166; 14.CD.230.169; 14.CD.230.172; 14.CD.230.175; 14.CD.230.240; 14.CD.230.244; 14.CD.231.228; 14.CD.231.229; 14.CD.231.230; 14.CD.231.231; 14.CD.231.236; 14.CD.231.237; 14.CD.231.238; 14.CD.231.239; 14.CD.231.154; 14.CD.231.157; 14.CD.231.166; 14.CD.231.169; 14.CD.231.172; 14.CD.231.175; 14.CD.231.240; 14.CD.231.244; 14.CD.236.228; 14.CD.236.229; 14.CD.236.230; 14.CD.236.231; 14.CD.236.236; 14.CD.236.237; 14.CD.236.238; 14.CD.236.239; 14.CD.236.154; 14.CD.236.157; 14.CD.236.166; 14.CD.236.169; 14.CD.236.172; 14.CD.236.175; 14.CD.236.240; 14.CD.236.244; 14.CD.237.228; 14.CD.237.229; 14.CD.237.230; 14.CD.237.231; 14.CD.237.236; 14.CD.237.237; 14.CD.237.238; 14.CD.237.239; 14.CD.237.154; 14.CD.237.157; 14.CD.237.166; 14.CD.237.169; 14.CD.237.172; 14.CD.237.175; 14.CD.237.240; 14.CD.237.244; 14.CD.238.228; 14.CD.238.229; 14.CD.238.230; 14.CD.238.231; 14.CD.238.236; 14.CD.238.237; 14.CD.238.238; 14.CD.238.239; 14.CD.238.154; 14.CD.238.157; 14.CD.238.166; 14.CD.238.169; 14.CD.238.172; 14.CD.238.175; 14.CD.238.240; 14.CD.238.244; 14.CD.239.228; 14.CD.239.229; 14.CD.239.230; 14.CD.239.231; 14.CD.239.236; 14.CD.239.237; 14.CD.239.238; 14.CD.239.239; 14.CD.239.154; 14.CD.239.157; 14.CD.239.166; 14.CD.239.169; 14.CD.239.172; 14.CD.239.175; 14.CD.239.240; 14.CD.239.244; 14.CD.154.228; 14.CD.154.229; 14.CD.154.230; 14.CD.154.231; 14.CD.154.236; 14.CD.154.237; 14.CD.154.238; 14.CD.154.239; 14.CD.154.154; 14.CU154.157; 14.CD.154.166; 14.CD.154.169; 14.CD.154.172; 14.CD.154.175; 14.CD.154.240; 14.CD.154.244; 14.CD.157.228; 14.CD.157.229; 14.CD.157.230; 14.CD.157.231; 14.CD.157.236; 14.CD.157.237; 14.CD.157.238; 14.CD.157.239; 14.CD.157.154; 14.CD.157.157; 14.CD.157.166; 14.CD.157.169; 14.CD.157.172; 14.CD.157.175; 14.CP.157.240; 14.CD.157.244; 14.CD.166.228; 14.CD.166.229; 14.CD.166.230; 14.CD.166.231; 14.CD.166.236; 14.CD.166.237; 14.CD.166.238; 14.CD.166.239; 14.CD.166.154; 14.CD.166.157; 14.CD.166.166; 14.CD.166.169; 14.CD.166.172; 14.CD.166.175; 14.CD.166.240; 14.CD.166.244; 14.CD.169.228; 14.CD.169.229; 14.CD.169.230; 14.CD.169.231; 14.CD.169.236; 14.CD.169.237; 14.CD.169.238; 14.CD.169.239; 14.CD.169.154; 14.CD.169.157; 14.CD.169.166; 14.CD.169.169; 14.CD.169.172; 14.CD.169.175; 14.CD.169.240; 14.CD.169.244; 14.CD.172.228; 14.CD.172.229; 14.CD.172.230; 14.CD.172.231; 14.CD.172.236; 14.CD.172.237; 14.CD.172.238; 14.CD.172.239; 14.CD.172.154; 14.CD.172.157; 14.CD.172.166; 14.CD.172.169; 14.CD.172.172; 14.CD.172.175; 14.CD.172.240; 14.CD.172.244; 14.CD.175.228; 14.CD.175.229; 14.CD.175.230; 14.CD.175.231; 14.CD.175.236; 14.CD.175.237; 14.CD.175.238; 14.CD.175.239; 14.CD.175.154; 14.CD.175.157; 14.CD.175.166; 14.CD.175.169; 14.CD.175.172; 14.CD.175.175; 14.CD.175.240; 14.CD.175.244; 14.CD.240.228; 14.CD.240.229; 14.CD.240.230; 14.CD.240.231; 14.CD.240.236; 14.CD.240.237; 14.CD.240.238; 14.CD.240.239; 14.CP.240.154; 14.CD.240.157; 14.CD.240.166; 14.CD.240.169; 14.CD.240.172; 14.CD.240.175; 14.CD.240.240; 14.CD.240.244; 14.CD.244.228; 14.CD.244.229; 14.CD.244.230; 14.CD.244.231; 14.CD.244.236; 14.CD.244.237; 14.CD.244.238; 14.CD.244.239; 14.CD.244.154; 14.CD.244.157; 14.CD.244.166; 14.CD.244.169; 14.CD.244.172; 14.CD.244.175; 14.CD.244.240; 14.CD.244.244;

Prodrugs of 14.EB

14.EB.228.228; 14.EB.228.229; 14.EB.228.230; 14.EB.228.231; 14.EB.228.236; 14.EB.228.237; 14.EB.228.238; 14.EB.228.239; 14.EB.228.154; 14.EB.228.157; 14.EB.228.166; 14.EB.228.169; 14. EB.228.172; 14.EB.228.175; 14.EB.228.240; 14.EB.228.244; 14.EB.229.228; 14.EB.229.229; 14.EB.229.230; 14.EB.229.231; 14.EB.229.236; 14.EB.229.237; 14.EB.229.238; 14.EB.229.239; 14.EB.229.154; 14.EB.229.157; 14.EB.229.166; 14.EB.229.169; 14.EB.229.172; 14.EB.229.175; 14.EB.229.240; 14.EB.229.244; 14.EB.230.228; 14.EB.230.229; 14.EB.230.230; 14.EB.230.231; 14.EB.230.236; 14.EB.230.237; 14.EB.230.238; 14.EB.230.239; 14.EB.230.154; 14.EB.230.157; 14.EB.230.166; 14.EB.230.169; 14.EB.230.172; 14.EB.230.175; 14.EB.230.240; 14.EB.230.244; 14.EB.231.228; 14.EB .231.229; 14.EB.231.230; 14.EB.231.231; 14.EB.231.236; 14.EB.231.237; 14.EB.231.238; 14.EB.231.239; 14.EB.231.154; 14.EB.231.157; 14.EB.231.166; 14.EB.231.169; 14.EB.231.172; 14.EB.231.175; 14.EB.231.240; 14.EB.231.244; 14.EB .236.228; 14.EB.236.229; 14.EB.236.230; 14.EB.236.231; 14.EB.236.236; 14.EB.236.237; 14.EB.236.238; 14.EB.236.239; 14.EB.236.154; 14.EB.236.157; 14.EB.236.166; 14.EB.236.169; 14.EB.236.172; 14.EB.236.175; 14.EB.236.240; 14.EB.236.244; 14.EB.237.228; 14.EB.237.229; 14.EB.237.230; 14.EB.237.231; 14.EB.237.236; 14.EB.237.237; 14.EB.237.238; 14.EB.237.239; 14.EB.237.154; 14.EB.237.157; 14.EB.237.166; 14.EB.237.169; 14.EB.237.172; 14.EB.237.175; 14.EB.237.240; 14.EB.237.244; 14.EB.238.228; 14.EB.238.229; 14.EB.238.230; 14.EB.238.231; 14.EB.238.236; 14.EB.238.237; 14.EB.238.238; 14.EB.238.239; 14.EB.238.154; 14.EB.238.157; 14.EB.238.166; 14.EB.238.169; 14.EB.238.172; 14.EB.238.175; 14.EB.238.240; 14.EB.238.244; 14.EB.239.228; 14.EB.239.229; 14.EB.239.230; 14.EB.239.231; 14.EB .239.236; 14.EB.239.237; 14.EB .239.238; 14.EB.239.239; 14.EB.239.154; 14.EB.239.157; 14.EB.239.166; 14.EB.239.169; 14.EB.239.172; 14.EB.239.175; 14.EB.239.240; 14.EB.239.244; 14.EB.154.228; 14.EB.154.229; 14.EB.154.230; 14.EB.154.231; 14.EB.154.236; 14.EB.154.237; 14.EB.154.238; 14.EB.154.239; 14.EB.154.154; 14.EB.154.157; 14.EB.154.166; 14.EB.154.169; 14.EB.154.172; 14.EB.154.175; 14.EB.154.240; 14.EB.154.244; 14.EB.157.228; 14.EB.157.229; 14.EB.157.230; 14.EB.157.231; 14.EB.157.236; 14.EB.157.237; 14.EB.157.238; 14.EB.157.239; 14.EB.157.154; 14.EB.157.157; 14.EB.157.166; 14.EB.157.169; 14.EB.157.172; 14.EB.157.175; 14.EB.157.240; 14.EB.157.244; 14.EB.166.228; 14.EB.166.229; 14.EB.166.230; 14.EB.166.231; 14.EB.166.236; 14.EB.166.237; 14.EB.166.238; 14.EB.166.239; 14.EB.166.154; 14.EB.166.157; 14.EB.166.166; 14.EB.166.169; 14.EB.166.172; 14.EB.166.175; 14.EB.166.240; 14.EB.166.244; 14.EB.169.228; 14.EB.169.229; 14.EB.169.230; 14.EB.169.231; 14.EB.169.236; 14.EB.169.237; 14.EB.169.238; 14.EB.169.239; 14.EB.169.154; 14.EB.169.157; 14.EB.169.166; 14.EB.169.169; 14.EB.169.172; 14.EB.169.175; 14.EB.169.240; 14.EB.169.244; 14.EB.172.228; 14.EB.172.229; 14.EB.172.230; 14.EB.172.231; 14.EB.172.236; 14.EB.172.237; 14.EB.172.238; 14.EB.172.239; 14.EB.172.154; 14.EB.172.157; 14.EB.172.166; 14.EB.172.169; 14.EB.172.172; 14.EB.172.175; 14.EB.172.240; 14.EB.172.244; 14. EB.175.228; 14.EB.175.229; 14.EB.175.230; 14.EB.175.231; 14.EB.175.236; 14.EB.175.237; 14.EB.175.238; 14.EB.175.239; 14.EB.175.154; 14.EB.175.157; 14.EB.175.166; 14.EB.175.169; 14.EB.175.172; 14.EB.175.175; 14.EB.175.240; 14.EB.175.244; 14.EB.240.228; 14.EB.240.229; 14.EB.240.230; 14.EB.240.231; 14.EB.240.236; 14.EB.240.237; 14.EB.240.238; 14.EB.240.239; 14.EB.240.154; 14.EB.240.157; 14.EB.240.166; 14.EB.240.169; 14.EB.240.172; 14.EB.240.175; 14.EB.240.240; 14.EB.240.244; 14.EB.244.228; 14.EB.244.229; 14.EB.244.230; 14.EB.244.231; 14.EB.244.236; 14.EB.244.237; 14.EB.244.238; 14.EB.244.239; 14.EB.244.154; 14.EB.244.157; 14.EB.244.166; 14.EB.244.169; 14.EB.244.172; 14.EB.244.175; 14.EB.244.240; 14.EB.244.244;

Prodrugs of 15.B

15.B.228.228; 15.B.228.229; 15.B.228.230; 15.B.228.231; 15.B.228.236; 15.B.228.237; 15.B.228.238; 15.B.228.239; 15.B.228.154; 15.B.228.157; 15.B.228.166; 15.B.228.169; 15.B.228.172; 15.B.228.175; 15.B.228.240; 15.B.228.244; 15.B.229.228; 15.B.229.229; 15.B.229.230; 15.B.229.231; 15.B.229.236; 15.B.229.237; 15.B.229.238; 15.B.229.239; 15.B.229.154; 15.B.229.157; 15.B.229.166; 15.B.229.169; 15.B.229.172; 15.B.229.175; 15.B.229.240; 15.B.229.244; 15.B.230.228; 15.B.230.229; 15.B.230.230; 15.B.230.231; 15.B.230.236; 15.B.230.237; 15.B.230.238; 15.B.230.239; 15.B.230.154; 15.B.230.157; 15.B.230.166; 15.B.230.169; 15.B.230.172; 15.B.230.175; 15.B.230.240; 15.B.230.244; 15.B.231.228; 15.B.231.229; 15.B.231.230; 15.B.231.231; 15.B.231.236; 15.B.231.237; 15.B.231.238; 15.B.231.239; 15.B.231.154; 15.B.231.157; 15.B.231.166; 15.B.231.169; 15.B.231.172; 15.B.231.175; 15.B.231.240; 15.B.231.244; 15.B.236.228; 15.B.236.229; 15.B.236.230; 15.B.236.231; 15.B.236.236; 15.B.236.237; 15.B.236.238; 15.B.236.239; 15.B.236.154; 15.B.236.157; 15.B.236.166; 15.B.236.169; 15.B.236.172; 15.B.236.175; 15.B.236.240; 15.B.236.244; 15.B-237.228; 15.B.237.229; 15.B.237.230; 15.B.237.231; 15.B.237.236; 15.B.237.237; 15.B.237.238; 15.B.237.239; 15.B.237.154; 15.B.237.157; 15.B.237.166; 15.B.237.169; 15.B.237.172; 15.B.237.175; 15.B.237.240; 15.B.237.244; 15.B.238.228; 15.B.238.229; 15.B.238.230; 15.B.238.231; 15.B.238.236; 15.B.238.237; 15.B.238.238; 15.B.238.239; 15.B.238.154; 15.B.238.157; 15.B.238.166; 15.B.238.169; 15.B.238.172; 15.B.238.175; 15.B.238.240; 15.B.238.244; 15.B.239.228; 15.B.239.229; 15.B.239.230; 15.B.239.231; 15.B.239.236; 15.B.239.237; 15.B.239.238; 15.B.239.239; 15.B.239.154; 15.B.239.157; 15.B.239.166; 15.B.239.169; 15.B.239.172; 15.B.239.175; 15.B.239.240; 15.B.239.244; 15.B.154.228; 15.B.154.229; 15.B.154.230; 15.B.154.231; 15.B.154.236; 15.B.154.237; 15.B.154.238; 15.B.154.239; 15.B.154.154; 15.B.154.157; 15.B.154.166; 15.B.154.169; 15.B.154.172; 15.B.154.175; 15.B.154.240; 15.B.154.244; 15.B.157.228; 15.B.157.229; 15.B.157.230; 15.B.157.231; 15.B.157.236; 15.B.157.237; 15.B.157.238; 15.B.157.239; 15.B.157.154; 15.B.157.157; 15.B.157.166; 15.B.157.169; 15.B.157.172; 15.B.157.175; 15.B.157.240; 15.B.157.244; 15.B.166.228; 15.B.166.229; 15.B.166-230; 15.B.166.231; 15.B.166.236; 15.B.166.237; 15.B.166.238; 15.B.166.239; 15.B.166.154; 15.B.166.157; 15.B.166.166; 15.B.166.169; 15.B.166.172; 15.B.166.175; 15.B.166.240; 15.B.166.244; 15.B.169.228; 15.B.169.229; 15.B.169.230; 15.B.169.231; 15.B.169.236; 15.B.169.237; 15.B.169.238; 15.B.169.239; 15.B.169.154; 15.B.169.157; 15.B.169.166; 15.B.169.169; 15.B.169.172; 15.B.169.175; 15.B.169.240; 15.B.169.244; 15.B.172.228; 15.B.172.229; 15.B.172.230; 15.B.172.231; 15.B.172.236; 15.B.172.237; 15.B.172.238; 15.B.172.239; 15.B.172.154; 15.B.172.157; 15.B.172.166; 15.B.172.169; 15.B.172.172; 15.B.172.175; 15.B.172.240; 15.B.172.244; 15.B.175.228; 15.B.175.229; 15.B.175.230; 15.B.175.231; 15.B.175.236; 15.B.175.237; 15.B.175.238; 15.B.175.239; 15.B.175.154; 153.175.157; 15.B.175.166; 15.B.175.169; 15.B.175.172; 15.B.175.175; 15.B.175.240; 15.B.175.244; 15.B.240.228; 15.B.240.229; 15.B.240.230; 15.B.240.231; 15.B.24Q.236; 15.B.240.237; 15.B.240.238; 15.B.240.239; 15.B.240.154; 15.B.240.157; 15.B.240.166; 15.B.240.169; 15.B.24Q.172; 15.B.240.175; 15.B.240.240; 15.B.240.244; 15.B.244.228; 15.B.244.229; 15.B.244.230; 15.B.244.231; 15.B.244.236; 15.B.244.237; 15.B.244.238; 15.B.244.239; 15.B.244.154; 15.B.244.157; 15.B.244.166; 15.B.244.169; 15.B.244.172; 15.B.244.175; 15.B.244.240; 15.B.244.244;

Prodrugs of 15.D

15.D.228.228; 15.D.228.229; 15.D.228.230; 15.D.228.231; 15.D.228.236; 15.D.228.237; 15.D.228.238; 15.D.228.239; 15.D.228.154; 15.D.228.157; 15.D.228.166; 15.D.228.169; 15.D.228.172; 15.D.228.175; 15.D.228.240; 15.D.228.244; 15.D.229.228; 15.D.229.229; 15.D.229.230; 15.D.229.231; 15.D.229.236; 15.D.229.237; 15.D.229.238; 15.D.229.239; 15.D.229.154; 15.D.229.157; 15.D.229.166; 15.D.229.169; 15.D.229.172; 15.D.229.175; 15.D.229.240; 15.D.229.244; 15.D.230.228; 15.D.230.229; 15.D.230.230; 15.D.230.231; 15.D.230.236; 15.D.230.237; 15.D.230.238; 15.D.230.239; 15.D.230.154; 15.D.230.157; 15.D.230.166; 15.D.230.169; 15.D.230.172; 15.D.230.175; 15.D.230.240; 15.D.230.244; 15.D.231.228; 15.D.231.229; 15.D.231.230; 15.D.231.231; 15.D.231.236; 15.D.231.237; 15.D.231.238; 15.D.231.239; 15.D.231.154; 15.D.231.157; 15.D.231.166; 15.D.231.169; 15.D.231.172; 15.D.231.175; 15.D.231.240; 15.D.231.244; 15.D.236.228; 15.D.236.229; 15.D.236.230; 15.D.236.231; 15.D.236.236; 15.D.236.237; 15.D.236.238; 15.D.236.239; 15.D.236.154; 15.D.236.157; 15.D.236.166; 15.D.236.169; 15.D.236.172; 15.D.236.175; 15.D.236.240; 15.D.236.244; 15.D.237.228; 15.D.237.229; 15.D.237.230; 15.D.237.231; 15.D.237.236; 15.D.237.237; 15.D.237.238; 15.D.237.239; 15.D.237.154; 15.D.237.157; 15.D.237.166; 15.D.237.169; 15.D.237.172; 15.D.237.175; 15.D.237.240; 15.D.237.244; 15.D.238.228; 15.D.238.229; 15.D.238.230; 15.D.238.231; 15.D.238.236; 15.D.238.237; 15.D.238.238; 15.D.238.239; 15.D.238.154; 15.D.238.157; 15.D.238.166; 15.D.238.169; 15.D.238.172; 15.D.238.175; 15.D.238.240; 15.D.238.244; 15.D.239.228; 15.D.239.229; 15.D.239.230; 15.D.239.231; 15.D.239.236; 15.D.239.237; 15.D.239.238; 15.D.239.239; 15.D.239.154; 15.D.239.157; 15.D.239.166; 15.D.239.169; 15.D.239.172; 15.D.239.175; 15.D.239.24Q; 15.D.239.244; 15.D.154.228; 15.D.154.229; 15.D.154.230; 15.D.154.231; 15.D.154.236; 15.D.154.237; 15.D.154.238; 15.D.154.239; 15.D.154.154; 15.D.154.157; 15.D.154.166; 15.D.154.169; 15.D.154.172; 15.D.154.175; 15.D.154.240; 15.D.154.244; 15.D.157.228; 15.D.157.229; 15.D.157.230; 15.D.157.231; 15.D.157.236; 15.D.157.237; 15.D.157.238; 15.D.157.239; 15.D.157.154; 15.D.157.157; 15.D.157.166; 15.D.157.169; 15.D.157.172; 15.D.157.175; 15.D.157.240; 15.D.157.244; 15.D.166.228; 15.D.166.229; 15.D.166.230; 15.D.166.231; 15.D.166.236; 15.D.166.237; 15.D.166.238; 15.D.166.239; 15.D.166.154; 15.D.166.157; 15.D.166.166; 15.D.166.169; 15.D.166.172; 15.D.166.175; 15.D.166.240; 15.D.166.244; 15.D.169.228; 15.D.169.229; 15.D.169.230; 15.D.169.231; 15.D.169.236; 15.D.169.237; 15.D.169.238; 15.D.169.239; 15.D.169.154; 15.D.169.157; 15.D.169.166; 15.D.169.169; 15.D.169.172; 15.D.169.175; 15.D.169.240; 15.D.169.244; 15.D.172.228; 15.D.172.229; 15.D.172.230; 15.D.172.231; 15.D.172.236; 15.D.172.237; 15.D.172.238; 15.D.172.239; 15.D.172.154; 15.D.172.157; 15.D.172.166; 15.D.172.169; 15.D.172.172; 15.D.172.175; 15.D.172.240; 15.D.172.244; 15.D.175.228; 15.D.175.229; 15.D.175.230; 15.D.175.231; 15.D.175.236; 15.D.175.237; 15.D.175.238; 15.D.175.239; 15.D.175.154; 15. D.175.157; 15.D.175.166; 15.D.175.169; 15.D.175.172; 15.D.175.175; 15.D.175.240; 15.D.175.244; 15.D.24Q.228; 15.D.240.229; 15.D.240.230; 15.D.240.231; 15.D.240.236; 15.D.240.237; 15.D.240.238; 15.D.240.239; 15.D.240.154; 15.D.240.157; 15.D.240.166; 15.D.240.169; 15.D.240.172; 15.D.240.175; 15.D.240.240; 15.D.240.244; 15.D.244.228; 15.D.244.229; 15.D.244.230; 15.D.244.231; 15.D.244.236; 15.D.244.237; 15.D.244.238; 15.D.244.239; 15.D.244.154; 15.D.244.157; 15.D.244.166; 15.D.244.169; 15.D.244.172; 15.D.244.175; 15.D.244.240; 15.D.244.244;

Prodrugs of 15.AB

15.AB.228.228; 15.AB.228.229; 15.AB.228.230; 15.AB.228.231; 15.AB.228.236; 15.AB.228.237; 15.AB.228.238; 15.AB.228.239; 15.AB.228.154; 15.AB.228.157; 15.AB.228.166; 15.AB.228.169; 15.AB.228.172; 15.AB.228.175; 15.AB.228.240; 15.AB.228.244; 15.AB.229.228; 15.AB.229.229; 15.AB.229.230; 15.AB.229.231; 15.AB, .229.236; 15.AB .229.237; 15.AB 229.238; 15.AB .229.239; 15.AB.229.154; 15.AB, .229.157; 15.AB .229.166; 15.AB 229.169; 15.AB 229.172; 15.AB.229.175; 15.AB. ,229.240; 15.AB 229.244; 15.AB, 230.228; 15.AB, 230.229; 15.AB.230230; 15.AB, ,230.231; 15.AB 230.236; 15.AB, 230.237; 15.AB, 230.238; 15.AB.230.239; 15.AB, ,230.154; 15.AB .230.157; 15.AB, .230.166; 15.AB, .230.169; 15.AB.230.172; 15.AB, ,230.175; 15.AB 230.240; 15.AB 230244; 15.AB, 231.228; 15.AB.231.229; 15.AB, ,231.230; 15.AB 231.231; 15.AB 231.236; 15.AB 231.237; 15.AB.231.238; 15.AB, ,231.239; 15.AB 231.154; 15.AB 231.157; 15.AB .231.166; 15.AB.231.169; 15.AB, ,231.172; 15.AB .231.175; 15.AB .231240; 15.AB .231244; 15.AB.236.228; 15.AB, ,236.229; 15.AB 236.230; 15.AB .236.231; 15.AB .236.236; 15.AB.236.237; 15.AB, ,236.238; 15.AB 236.239; 15.AB .236.154; 15.AB 236.157; 15.AB, 236.166; 15.AB, ,236.169; 15.AB 236.172; 15.AB .236.175; 15.AB .236.240; 15.AB, 236.244; 15.AB, ,237.228; 15.AB 237.229; 15.AB 237.230; 15.AB .237.231; 15.AB, 237.236; 15.AB, ,237.237; 15.AB .237.238; 15.AB 237239; 15.AB 237.154; 15.AB, 237.157; 15.AB, .237.166; 15.AB .237.169; 15.AB .237.172; 15.AB 237.175; 15.AB, ,237.240; 15.AB .237.244; 15.AB .238.228; 15.AB 238.229; 15.AB 238.230; 15.AB, 238231; 15.AB .238.236; 15.AB .238.237; 15.AB 238.238; 15.AB .238.239; 15.AB 238.154; 15.AB .238.157; 15.AB .238.166; 15.AB 238.169; 15.AB .238.172; 15.AB .238.175; 15.AB .238.240; 15.AB 238244; 15.AB .239.228; 15.AB .239.229; 15.AB .239.230; 15.AB, ,239.231; 15.AB 239.236; 15.AB .239237; 15.AB .239.238; 15.AB, 239239; 15.AB, ,239.154; 15.AB 239.157; 15.AB 239.166; 15.AB 239.169; 15.AB, ,239.172; 15.AB, ,239.175; 15.AB .239.240; 15.AB 239.244; 15.AB .154.228; 15.AB, 154.229; 15.AB .154.230; 15.AB .154.231; 15.AB .154236; 15.AB .154.237; 15.AB, 154.238; 15.AB .154.239; 15.AB .154.154; 15.AB .154.157; 15.AB .154.166; 15.AB, 154.169; 15.AB .154.172; 15.AB .154.175; 15.AB .154.240; 15.AB .154.244; 15.AB 157.228; 15.AB .157.229; 15.AB .157230; 15.AB .157.231; 15.AB .157.236; 15.AB 157237; 15.AB, .157.238; 15.AB .157.239; 15.AB .157.154; 15.AB .157.157; 15.AB .157.166; 15.AB .157.169; 15.AB .157.172; 15.AB .157.175; 15.AB .157.240; 15.AB .157.244; 15.AB 166.228; 15.AB .166.229; 15.AB .166.230; 15.AB .166.231; 15.AB .166.236; 15.AB, .166.237; 15.AB .166.238; 15.AB .166.239; 15.AB .166.154; 15.AB 166.157; 15.AB, .166.166; 15.AB .166.169; 15.AB .166.172; 15.AB .166.175; 15.AB 166.240; 15.AB, 166.244; 15.AB .169.228; 15.AB .169.229; 15.AB .169.230; 15.AB .169.231; 15.AB, 169.236; 15.AB .169.237; 15.AB .169.238; 15.AB .169.239; 15.AB .169.154; 15.AB, 169.157; 15.AB .169.166; 15.AB .169.169; 15.AB .169.172; 15.AB 169.175; 15.AB, 169.240; 15.AB .169244; 15.AB .172.228; 15.AB .172.229; 15.AB 172.230; 15.AB.172.231; 15.AB, .172236; 15.AB .172.237; 15.AB .172.238; 15.AB, 172239; 15.AB.172.154; 15.AB, .172.157; 15.AB .172.166; 15.AB .172.169; 15.AB, 172.172; 15.AB.172.175; 15.AB, .172240; 15.AB .172.244; 15.AB .175.228; 15.AB, 175.229; 15.AB.175.230; 15.AB .175.231; 15.AB .175236; 15.AB .175.237; 15.AB, 175.238; 15.AB.175.239; 15.AB .175.154; 15.AB .175.157; 15.AB .175.166; 15.AB, 175.169; 15.AB.175.172; 15.AB .175.175; 15.AB .175.240; 15.AB .175.244; 15.AB, 240.228; 15.AB.240.229; 15.AB 240230; 15.AB 240.231; 15.AB .240.236; 15.AB, 240.237; 15.AB.240.238; 15.AB .240.239; 15.AB .240.154; 15.AB 240.157; 15.AB, 240.166; 15.AB.240.169; 15.AB 240.172; 15.AB .240.175; 15.AB 240.240; 15.AB, 240.244; 15.AB.244.228; 15.AB .244.229; 15.AB 244.230; 15.AB 244.231; 15.AB, 244.236; 15.AB.244.237; 15.AB 244.238; 15.AB .244239; 15.AB .244.154; 15.AB, 244.157; 15.AB.244.166; 15.AB.244.169; 15.AB.244.172; 15.AB.244.175; 15.AB.244.240; 15.AB.244.244;

Prodrugs of 15.BI

15.BI.228.228; 15.BI.228.229; 15.BI.228.230; 15.BI.228.231; 15.BI.228.236; 15.BI.228.237; 15.BI.228.238; 15.BI.228.239; 15.BI.228.154; 15.BI.228.157; 15.BI.228.166; 15.BI.228.169; 15.BI.228.172; 15.BI.228.175; 15.BI.228.240; 15.BI.228.244; 15.BI.229.228; 15.BI.229.229; 15.BI.229.230; 15.BI.229.231; 15.BI.229.236; 15.BI.229.237; 15.BI.229.238; 15.BI.229.239; 15.BI.229.154; 15.BI.229.157; 15.BI.229.166; 15.BI.229.169; 15.BI.229.172; 15.BI.229.175; 15.BI.229.240; 15.BI.229.244; 15.BI.230.228; 15.BI.230.229; 15.BI.230.230; 15.BI.230.231; 15.BI.230.236; 15.BI.230.237; 15.BI.23Q.238; 15.BI.230.239; 15.BI.230.154; 15.BI.230.157; 15.BI.230.166; 15.BI.230.169; 15.BI.230.172; 15.BI.230.175; 15.BI.230.240; 15.BI.230.244; 15.BI.231.228; 15.BI.231.229; 15.BI.231.230; 15.BI.231.231; 15.BI.231.236; 15.BI.231.237; 15.BI.231.238; 15.BI.231.239; 15.BI.231.154; 15.BI.231.157; 15.BI.231.166; 15.BI.231.169; 15.BI.231.172; 15.BI.231.175; 15.BI.231.240; 15.BI.231.244; 15.BI.236.228; 15.BI.236.229; 15.BI.236.230; 15.BI.236.231; 15.BL236.236; 15.BI.236.237; 15.BI.236.238; 15.BI.236.239; 15.BI.236.154; 15.BI.236.157; 15.BI.236.166; 15.BL236.169; 15.BI.236.172; 15.BI.236.175; 15.BI.236.240; 15.BI.236.244; 15.BI.237.228; 15.BI.237.229; 15.BI.237.230; 15.BI.237.231; 15.BL237.236; 15.BI.237.237; 15.BI.237.238; 15.BL237.239; 15.BI.237.154; 15.BI.237.157; 15.BI.237.166; 15.BI.237.169; 15.BI.237.172; 15.BI.237.175; 15.BI.237.240; 15.BI.237.244; 15.BI.238.228; 15.BI.238.229; 15.BI.238.230; 15.BI.238.231; 15.BI.238.236; 15.BI.238.237; 15.BI.238.238; 15.BI.238.239; 15.BI.238.154; 15.BI.238.157; 15.BI.238.166; 15.BI.238.169; 15.BI.238.172; 15.BI.238.175; 15.BI.238.240; 15.BI.238.244; 15.BI.239.228; 15.BI.239.229; 15.BI.239.230; 15.BI.239.231; 15.BI.239.236; 15.BI.239.237; 15.BI.239.238; 15.BI.239.239; 15.BI.239.154; 15.BI.239.157; 15.BI.239.166; 15.BI.239.169; 15.BI.239.172; 15.BI.239.175; 15.BI.239.240; 15.BI.239.244; 15.BI.154.228; 15.BL154.229; 15.BI.154.230; 15.BI.154.231; 15.BI.154.236; 15.BI.154.237; 15.BI.154.238; 15.BI.154.239; 15.BI.154.154; 15.BI.154.157; 15.BL154.166; 15.BI.154.169; 15.BI.154.172; 15.BI.154.175; 15.BI.154.240; 15.BI.154.244; 15.BI.157.228; 15.BI.157.229; 15.BI.157.230; 15.BI.157.231; 15.BL157.236; 15.BI.157.237; 15.BI.157.238; 15.BI.157.239; 15.BI.157.154; 15.BI.157.157; 15.BI.157.166; 15.BI.157.169; 15.BI.157.172; 1531.157.175; 15.BL157.240; 15.BI.157.244; 15.BI.166.228; 15.BI.166.229; 15.BI.166.230; 15.BI.166.231; 15.BI.166.236; 15.BI.166.237; 15.BI.166.238; 15.BI.166.239; 15.BL166.154; 15.BI.166.157; 15.BI.166.166; 15.BI.166.169; 15.BI.166.172; 15.BI.166.175; 15.BI.166.240; 15.BI.166.244; 15.BI.169.228; 15.BI.169.229; 15.BI.169.230; 15.BI.169.231; 15.BI.169.236; 15.BI.169.237; 15.BI.169.238; 15.BI.169.239; 15.BI.169.154; 15.BI.169.157; 15.BI.169.166; 15.BI.169.169; 15.BI.169.172; 15.BI.169.175; 15.BI.169.240; 15.BI.169.244; 15.BI.172.228; 15.BI.172.229; 15.BI.172.230; 15.BI.172.231; 15.BI.172.236; 15.BI.172.237; 15.BI.172.238; 15.BI.172.239; 15.BI.172.154; 15.BI.172.157; 15.BI.172.166; 15.BI.172.169; 15.BI.172.172; 15.BI.172.175; 15.BI.172.240; 15.BI.172.244; 15.BI.175.228; 15.BI.175.229; 15.BI.175.230; 15.BI.175.231; 15.BI.175.236; 15.BI.175.237; 15.BI.175.238; 15.BI.175.239; 15.BI.175.154; 15.BI.175.157; 15.BI.175.166; 15.BI.175.169; 15.BI.175.172; 15.BI.175.175; 15.BI.175.240; 15.BI.175.244; 15.BI.240.228; 15.BI.240.229; 15.BI.240.230; 15.BI.240.231; 15.BI.240.236; 15.BI.240.237; 15.BI.240.238; 15.BI.240.239; 15.BI.240.154; 15.BI.240.157; 15.BI.240.166; 15.BI.240.169; 15.BI.240.172; 15.BI.240.175; 15.BI.240.240; 15.BI.240.244; 15.BI.244.228; 15.BI.244.229; 15.BI.244.230; 15.BL244.231; 15.BI.244.236; 15.BI.244.237; 15.BI.244.238; 15.BI.244.239; 15.BI.244.154; 15.BI.244.157; 15.BI.244.166; 15.BI.244.169; 15.BI.244.172; 15.BI.244.175; 15.BI.244.240; 15.BI.244.244;

Prodrugs of 15.1

15.1.228.228; 15.1.228.229; 15.1.228.230; 15.1.228.231; 15.1.228.236; 15.1.228.237; 15.1.228.238; 15.1.228.239; 15.1.228.154; 15.1.228.157; 15.1.228.166; 15.1.228.169; 15.1.228.172; 15.1.228.175; 15.1.228.240; 15.1.228.244; 15.1.229.228; 15.1.229.229; 15.1.229.230; 15.1.229.231; 15.1.229.236; 15.1.229.237; 15.1.229.238; 15.1.229.239; 15.1.229.154; 15.1.229.157; 15.1.229.166; 15.1.229.169; 15.1.229.172; 15.1.229.175 ; 15.1.229.240; 15.1.229.244; 15.1.230.228; 15.1.230.229; 15.1.230.230; 15.1.230.231; 15.1.230.236; 15.1.230.237; 15.1.230.238; 15.1.230.239; 15.1.230.154; 15.1.230.157; 15.1.230.166; 15.1.230.169; 15.1.230.172; 15.1.230.175; 15.1.230.240; 15.1.230.244; 15.1.231.228; 15.1.231.229; 15.1.231.230; 15.1.231.231; 15.1.231.236; 15.1.231.237; 15.1.231.238; 15.1.231.239; 15.1.231.154; 15.1.231.157; 15.1.231.166; 15.1.231.169; 15.1.231.172; 15.1.231.175; 15.1.231.240; 15.1.231.244; 15.1.236.228; 15.1.236.229; 15.1.236.230; 15.1.236.231; 15.1.236.236; 15.1.236.237; 15.1.236.238; 15.1.236.239; 15.1.236.154; 15.1.236.157; 15.1.236.166; 15.1.236.169; 15.1.236.172; 15.1.236.175; 15.1.236.240; 15.1.236.244; 15.1.237.228; 15.1.237.229; 15.1.237.230; 15.1.237.231; 15.1.237.236; 15.1.237.237; 15.1.237.238; 15.1.237.239; 15.1.237.154; 15.1.237.157; 15.1.237.166; 15.1.237.169; 15.1.237.172; 15.1.237.175; 15.1.237.240; 15.1.237.244; 15.1.238.228; 15.1.238.229; 15.1.238.230; 15.1.238.231; 15.1.238.236; 15.1.238.237; 15.1.238.238; 15.1.238.239; 15.1.238.154; 15.1.238.157; 15.1.238.166; 15.1.238.169; 15.1.238.172; 15.1.238.175; 15.1.238.240; 15.1.238.244; 15.1.239.228; 15.1.239.229; 15.1.239.230; 15.1.239.231; 15.1.239.236; 15.1.239.237; 15.1.239.238; 15.1.239.239; 15.1.239.154; 15.1.239.157; 15.1.239.166; 15.1.239.169; 15.1.239.172; 15.1.239.175; 15.1.239.240; 15.1.239.244; 15.1.154.228; 15.1.154.229; 15.1.154.230; 15.1.154.231; 15.1.154.236; 15.1.154.237; 15.1.154.238; 15.1.154.239; 15.1.154.154; 15.1.154.157; 15.1.154.166; 15.1.154.169; 15.1.154.172; 15.1.154.175; 15.1.154.240; 15.1.154.244; 15.1.157.228; 15.1.157.229; 15.1.157.230; 15.1.157.231; 15.1.157.236; 15.1.157.237; 15.1.157.238; 15.1.157.239; 15.1.157.154; 15.1.157.157; 15.1.157.166; 15.1.157.169; 15.1.157.172; 15.1.157.175; 15.1.157.240; 15.1.157.244; 15.1.166.228; 15.1.166.229; 15.1.166.230; 15.1.166.231; 15.1.166.236; 15.1.166.237; 15.1.166.238; 15.1.166.239; 15.1.166.154; 15.1.166.157; 15.1.166.166; 15.1.166.169; 15.1.166.172; 15.1.166.175; 15.1.166.240; 15.1.166.244; 15.1.169.228; 15.1.169.229; 15.1.169.230; 15.1.169.231; 15.1.169.236; 15.1.169.237; 15.1.169.238; 15.1.169.239; 15.1.169.154; 15.1.169.157; 15.1.169.166; 15.1.169.169; 15.1.169.172; 15.1.169.175; 15.1.169.240; 15.1.169.244; 15.1.172.228; 15.1.172.229; 15.1.172.230; 15.1.172.231; 15.1.172.236; 15.1.172.237; 15.1.172.238; 15.1.172.239; 15.1.172.154; 15.1.172.157; 15.1.172.166; 15.1.172.169; 15.1.172.172; 15.1.172.175; 15.1.172.240; 15.1.172.244; 15.1.175.228; 15.1.175.229; 15.1.175.230; 15.1.175.231; 15.1.175.236; 15.1.175.237; 15.1.175.238; 15.1.175.239; 15.1.175.154; 15.1.175.157; 15.1.175.166; 15.1.175.169; 15.1.175.172; 15.1.175.175; 15.1.175.240; 15.1.175.244; 15.1.240.228; 15.1.240.229; 15.1.240.230; 15.1.240.231; 15.1.240.236; 15.1.240.237; 15.1.240.238; 15.1.240.239; 15.1.240.154; 15.1.240.157; 15.1.240.166; 15.1.240.169; 15.1.240.172; 15.1.240.175; 15.1.240.240; 15.1.240.244; 15.1.244.228; 15.1.244.229; 15.1.244.230; 15.1.244.231; 15.1.244.236; 15.1.244.237; 15.1.244.238; 15.1.244.239; 15.1.244.154; 15.1.244.157; 15.1.244.166; 15.1.244.169; 15.1.244.172; 15.1.244.175; 15.1.244.240; 15.1.244.244;

Prodrugs of 15J

15.J.228.228; 15.J.228.229; 15.J.228.230; 15.J.228.231; 15.J.228.236; 15.J.228.237; 15.J.228.238; 15J.228.239; 15.J.228.154; 15.J.228.157; 15.J.228.166; 15.J.228.169; 15.J.228.172; 15J.228.175; 15J.228.240; 15J.228.244; 15J.229.228; 15J.229.229; 15J.229.230; 15J.229.231; 15J.229.236; 15J.229.237; 15J.229.238; 15.J.229.239; 15J.229.154; 15J.229.157; 15.J.229.166; 15J.229.169; 15J.229.172; 15J.229.175; 15J.229.240; 15J.229.244; 15J.230.228; 15J.230.229; 15J.230.230; 15J.230.231; 15J.230.236; 15J.230.237; 15J.230.238; 15J.230.239; 15J.230.154; 15J.230.157; 15J.230.166; 15J.230.169; 15J.230.172; 15J.230.175; 15J.230.240; 15J.230.244; 15.J.231.228; 15J.231.229; 15J.231.230; 15J.231.231; 15J.231.236; 15J.231.237; 15J.231.238; 15J.231.239; 15J.231.154; 15J.231.157; 15J.231.166; 15J.231.169; 15J.231.172; 15J.231.175; 15J.231.240; 15J.231.244; 15J.236.228; 15J.236.229; 15.J.236.230; 15J.236.231; 15J.236.236; 15J.236.237; 15.J.236.238; 15J.236.239; 15J.236.154; 15J.236.157; 15J.236.166; 15J.236.169; 15J.236.172; 15J.236.175; 15J.236.240; 15J.236.244; 15J.237.228; 15J.237.229; 15J.237.230; 15J.237.231; 15J.237.236; 15J.237.237; 15.J.237.238; 15J.237.239; 15J.237.154; 15.J.237.157; 15J.237.166; 15J.237.169; 15J.237.172; 15.J.237.175; 15J.237.240; 15J.237.244; 15J.238.228; 15J.238.229; 15J.238.230; 15J.238.231; 15J.238.236; 15J.238.237; 15J.238.238; 15J.238.239; 15J.238.154; 15J.238.157; 15.J.238.166; 15J.238.169; 15J.238.172; 15J.238.175; 15J.238.240; 15J.238.244; 15J.239.228; 15J.239.229; 15J.239.230; 15J.239.231; 15J.239.236; 15J.239.237; 15J.239.238; 15J.239.239; 15J.239.154; 15J.239.157; 15J.239.166; 15J.239.169; 15J.239.172; 15J.239.175; 15J.239.240; 15J.239.244; 15J.154.228; 15J.154.229; 15.J.154.230; 15J.154.231; 15J.154.236; 15J.154.237; 15J.154.238; 15J.154.239; 15J.154.154; 15J.154.157; 15J.154.166; 15J.154.169; 15J.154.172; 15J.154.175; 15J.154.240; 15J.154.244; 15J.157.228; 15J.157.229; 15J.157.230; 15J.157.231; 15J.157.236; 15.J.157.237; 15J.157.238; 15.J.157.239; 15J.157.154; 15J.157.157; 15J.157.166; 15J.157.169; 15J.157.172; 15J.157.175; 15J.157.240; 15J.157.244; 15J.166.228; 15J.166.229; 15J.166.230; 15J.166.231; 15J.166.236; 15J.166.237; 15J.166.238; 15J.166.239; 15J.166.154; 15J.166.157; 15J.166.166; 15J.166.169; 15J.166.172; 15J.166.175; 15J.166.240; 15J.166.244; 15J.169.228; 15J.169.229; 15J.169.230; 15J.169.231; 15.J.169.236; 15.J.169.237; 15J.169.238; 15J.169.239; 15J.169.154; 15.J.169.157; 15J.169.166; 15J.169.169; 15J.169.172; 15J.169.175; 15J.169.240; 15J.169.244; 15J.172.228; 15J.172.229; 15J.172.230; 15J.172.231; 15J.172.236; 15J.172.237; 15J.172.238; 15.J.172.239; 15J.172.154; 15.J.172.157; 15J.172.166; 15J.172.169; 15J.172.172; 15J.172.175; 15J.172.240; 15J.172.244; 15J.175.228; 15J.175.229; 15.J.175.230; 15J.175.231; 15J.175.236; 15.J.175.237; 15.J.175.238; 15.J.175.239; 15.J.175.154; 15J.175.157; 15J.175.166; 15J.175.169; 15J.175.172; 15J.175.175; 15J.175.240; 15J.175.244; 15J.240.228; 15J.240.229; 15J.240.230; 15J.240.231; 15J.240.236; 15J.240.237; 15.J.240.238; 15J.240.239; 15J.240.154; 15J.240.157; 15J.240.166; 15J.240.169; 15J.240.172; 15J.240.175; 15J.240.240; 15J.240.244; 15J.244.228; 15J.244.229; 15J.244.230; 15J.244.231; 15J.244.236; 15J.244.237; 15 J.244.238; 15J.244.239; 15J.244.154; 15J.244.157; 15J.244.166; 15J.244.169; 15J.244.172; 15 J.244.175; 15J.244.240; 15J.244.244;

Prodrugs of 15. L

15.L.228.228; 15.L.228.229; 15.L.228.230; 15.L.228.231; 15.L.228.236; 15.L.228.237; 15.L.228.238; 15.L.228.239; 15.L.228.154; 15.L.228.157; 15.L.228.166; 15.L.228.169; 15.L.228.172; 15.L.228.175; 15.L.228.240; 15.L.228.244; 15.L.229.228; 15.L.229.229; 15.L.229.230; 15.L.229.231; 15.L.229.236; 15.L.229.237; 15.L.229.238; 15.L.229.239; 15.L.229.154; 15.L.229.157; 15.L.229.166; 15.L.229.169; 15.L.229.172; 15.L.229.175; 15.L.229.240; 15.L.229.244; 15.L.230.228; 15.L.230.229; 15.L.230-230; 15.L.230.231; 15.L.230.236; 15.L.230.237; 15.L.230.238; 15.L.230.239; 15.L.230.154; 15.L.230.157; 15.L.230.166; 15.L.230.169; 15.L.230.172; 15.L.230.175; 15.L.230.240; 15.L.230.244; 15.L.231.228; 15.L.231.229; 15.L.231.230; 15.L.231.231; 15.L.231.236; 15.L.231.237; 15.L.231.238; 15.L.231.239; 15.L.231.154; 15.L.231.157; 15.L.231.166; 15.L.231.169; 15.L.231.172; 15.L.231.175; 15.L.231.240; 15.L.231.244; 15.L.236.228; 15.L.236.229; 15.L.236.230; 15.L.236.231; 15.L.236.236; 15.L.236.237; 15.L.236.238; 15.L.236.239; 15.L.236.154; 15.L.236.157; 15.L.236.166; 15.L.236.169; 15.L.236.172; 15.L.236.175; 15.L.236.240; 15.L.236.244; 15.L.237.228; 15.L.237.229; 15.L.237.230; 15.L.237.231; 15.L.237.236; 15.L.237.237; 15.L.237.238; 15.L.237.239; 15.L.237.154; 15.L.237.157; 15.L.237.166; 15.L.237.169; 15.L.237.172; 15.L.237.175; 15.L.237.240; 15.L.237.244; 15.L.238.228; 15.L.238.229; 15.L.238.230; 15.L.238.231; 15.L.238.236; 15.L.238.237; 15.L.238.238; 15.L.238.239; 15.L.238.154; 15.L.238.157; 15.L.238.166; 15.L.238.169; 15.L.238.172; 15.L.238.175; 15.L.238.240; 15.L.238.244; 15.L.239.228; 15.L.239.229; 15.L.239.230; 15.L.239.231; 15.L.239.236; 15.L.239.237; 15.L.239.238; 15.L.239.239; 15.L.239.154; 15.L.239.157; 15.L.239.166; 15.L.239.169; 15.L.239.172; 15.L.239.175; 15.L.239.240; 15.L.239.244; 15.L.154.228; 15.L.154.229; 15.L.154.230; 15.L.154.231; 15.L.154.236; 15.L.154.237; 15.L.154.238; 15.L.154.239; 15.L.154.154; 15.L.154.157; 15.L.154.166; 15.L.154.169; 15.L.154.172; 15.L.154.175; 15.L.154.240; 15.L.154.244; 15.L.157.228; 15.L.157.229; 15.L.157.230; 15.L.157.231; 15.L.157.236; 15.L.157.237; 15.L.157.238; 15.L.157.239; 15.L.157.154; 15.L.157.157; 15.L.157.166; 15.L.157.169; 15.L.157.172; 15.L.157.175; 15.L.157.240; 15.L.157.244; 15.L.166.228; 15.L.166.229; 15.L.166.230; 15.L.166.231; 15.L.166.236; 15.L.166.237; 15.L.166.238; 15.L.166.239; 15.L.166.154; 15.L.166.157; 15.L.166.166; 15.L.166.169; 15.L.166.172; 15.L.166.175; 15.L.166.240; 15.L.166.244; 15.L.169.228; 15.L.169.229; 15.L.169.230; 15.L.169.231; 15.L.169.236; 15.L.169.237; 15.L.169.238; 15.L.169.239; 15.L.169.154; 15.L.169.157; 15.L.169.166; 15.L.169.169; 15.L.169.172; 15.L.169.175; 15.L.169.240; 15.L.169.244; 15.L.172.228; 15.L.172.229; 15.L.172.230; 15.L.172.231; 15.L.172.236; 15.L.172.237; 15.L.172.238; 15.L.172.239; 15.L.172.154; 15.L.172.157; 15X.172.166; 15.L.172.169; 15.L.172.172; 15.L.172.175; 15.L.172.240; 15.L.172.244; 15.L.175.228; 15.L.175.229; 15.L.175.230; 15.L.175.231; 15.L.175.236; 15.L.175.237; 15.L.175.238; 15.L.175.239; 15.L.175.154; 15.L.175.157; 15.L.175.166; 15.L.175.169; 15.L.175.172; 15.L.175.175; 15.L.175.240; 15.L.175.244; 15.L.240.228; 15.L.240.229; 15.L.240.230; 15.L.240.231; 15.L.240.236; 15.L.240.237; 15.L.240.238; 15.L.240.239; 15.L.240.154; 15.L.240.157; 15.L.240.166; 15.L.240.169; 15.L.240.172; 15.L.240.175; 15.L.240.240; 15.L.240.244; 15.L.244.228; 15.L.244.229; 15.L.244.230; 15.L.244.231; 15.L.244.236; 15.L.244.237; 15.L.244.238; 15.L.244.239; 15.L.244.154; 15.L.244.157; 15.L.244.166; 15.L.244.169; 15.L.244.172; 15.L.244.175; 15.L.244.240; 15.L.244.244;

Prodrugs of 15.O

15.O.228.228; 15.O.228.229; 15.O.228.230; 15.O.228.231; 15.O.228.236; 15.O.228.237; 15.O.228.238; 15.O.228.239; 15.O.228.154; 15.O.228.157; 15.O.228.166; 15.O.228.169; 15.O.228.172; 15.O.228.175; 15.O.228.240; 15.O.228.244; 15.O.229.228; 15.O.229.229; 15.O.229.230; 15.O.229.231; 15.O.229.236; 15.O.229.237; 15.O.229.238; 15.O.229.239; 15.O.229.154; 15.O.229.157; 15.O-229.166; 15.O.229.169; 15.O.229.172; 15.O.229.175; 15.O.229.240; 15.O.229.244; 15.O.230.228; 15.O.230.229; 15.O.230.230; 15.O.230.231; 15.O.230.236; 15.O.230.237; 15.O.230.238; 15.O.230.239; 15.O.230.154; 15.O.230.157; 15.O.230.166; 15.O.230.169; 15.O.230.172; 15.O.230.175; 15.O.230.240; 15.O.230.244; 15.O.231.228; 15.O.231.229; 15.O.231.230; 15.O.231.231; 15.O.231.236; 15.O.231.237; 15.O.231.238; 15.O.231.239; 15.O.231.154; 15.O.231.157; 15.O.231.166; 15.O.231.169; 15.O.231.172; 15.O.231.175; 15.O.231.240; 15.O.231.244; 15.O.236.228; 15.O.236.229; 15.O.236.230; 15.O.236.231; 15.O.236.236; 15.O.236.237; 15.O.236.238; 15.O.236.239; 15.O.236.154; 15.O.236.157; 15.O.236.166; 15.O.236.169; 15.O.236.172; 15.O.236.175; 15.O.236.240; 15.O.236.244; 15.O.237.228; 15.O.237.229; 15.O.237.230; 15.O.237.231; 15.O.237.236; 15.O.237.237; 15.O.237.238; 15.O.237.239; 15.O.237.154; 15.O.237.157; 15.O.237.166; 15.O.237.169; 15.O.237.172; 15.O.237.175; 15.O.237.240; 15.O.237.244; 15.O.238.228; 15.O.238.229; 15.O.238.230; 15.O.238.231; 15.O.238.236; 15.O.238.237; 15.O.238.238; 15.O.238.239; 15.O.238.154; 15.O.238.157; 15.Q.238.166; 15.O.238.169; 15.O.238.172; 15.O.238.175; 15.O.238.240; 15.O-238.244; 15.O.239.228; 15.O.239.229; 15.O.239.230; 15.O.239.231; 15.O.239.236; 15.O.239.237; 15.O.239.238; 15.O.239.239; 15.O.239.154; 15.O.239.157; 15.O.239.166; 15.O.239.169; 15.O.239.172; 15.O.239.175; 15.O.239.240; 15.O.239.244; 15.O.154.228; 15.O.154.229; 15.O.154.230; 15.O.154.231; 15.O.154.236; 15.O.154.237; 15.O.154.238; 15.O.154.239; 15.O.154.154; 15.O.154.157; 15.O.154.166; 15.O.154.169; 15.O.154.172; 15.O.154.175; 15.O.154.240; 15.O.154.244; 15.O.157.228; 15.O.157.229; 15.O.157.230; 15.O.157.231; 15.O.157.236; 15.O.157.237; 15.O.157.238; 15.O.157.239; 15.O.157.154; 15.O.157.157; 15.O.157.166; 15.O.157.169; 15.O.157.172; 15.O.157.175; 15.O.157.240; 15.O.157.244; 15.O.166.228; 15.O.166.229; 15.O.166.230; 15.O.166.231; 15.O.166.236; 15.O.166.237; 15.O.166.238; 15.O.166.239; 15.O.166.154; 15.O.166.157; 15.O.166.166; 15.O.166.169; 15.O.166.172; 15.O.166.175; 15.O.166.240; 15.O.166.244; 15.O.169.228; 15.O.169.229; 15.O.169.230; 15.O.169.231; 15.O.169.236; 15.O.169.237; 15.O.169.238; 15.O.169.239; 15.O.169.154; 15.O.169.157; 15.O.169.166; 15.O.169.169; 15.O.169.172; 15.O.169.175; 15.O.169.240; 15.O.169.244; 15.O.172.228; 15.0-172.229; 15.O.172.230; 15.O.172.231; 15.O.172.236; 15.O.172.237; 15.O.172.238; 15.O.172.239; 15.O.172.154; 15.O.172.157; 15.O.172.166; 15.O.172.169; 15.O.172.172; 15.O.172.175; 15.O.172.240; 15.O.172.244; 15.O.175.228; 15.O.175.229; 15.O.175.230; 15.O.175.231; 15.O.175.236; 15.O.175.237; 15.O.175.238; 15.O.175.239; 15.O.175.154; 15.O.175.157; 15.O.175.166; 15.O.175.169; 15.O.175.172; 15.O.175.175; 15.O.175.240; 15.O.175.244; 15.O.240.228; 15.O.240.229; 15.O.240.230; 15.O.240.231; 15.O.240.236; 15.O.240.237; 15.O.240.238; 15.O.240.239; 15.O.240.154; 15.O.240.157; 15.O.240.166; 15.O.240.169; 15.O.240.172; 15.O.240.175; 15.O.240.240; 15.O.240.244; 15.O.244.228; 15.O.244.229; 15.O.244.230; 15.O.244.231; 15.O.244.236; 15.O.244.237; 15.O.244.238; 15.O.244.239; 15.O.244.154; 15.O.244.157; 15.O.244.166; 15.O.244.169; 15.O.244.172; 15.O.244.175; 15.O.244.240; 15.O.244.244;

Prodrugs of 15.P

15.P.228.228; 15.P.228.229; 15.P.228.230; 15.P.228.231; 15.P.228.236; 15.P.228.237; 15.P.228.238; 15.P.228.239; 15.P.228.154; 15.P.228.157; 15.P.228.166; 15.P.228.169; 15.P.228.172; 15.P.228.175; 15.P.228.240; 15.P.228.244; 15.P.229.228; 15.P.229.229; 15.P.229.230; 15.P.229.231; 15.P.229.236; 15.P.229.237; 15.P.229.238; 15.P.229.239; 15.P.229.154; 15.P.229.157; 15.P.229.166; 15.P.229.169; 15.P.229.172; 15.P.229.175; 15.P.229.240; 15.P.229.244; 15.P.230.228; 15.P.230.229; 15.P.230.230; 15.P.230.231; 15.P.230.236; 15.P.230.237; 15.P.230.238; 15.P.230.239; 15.P.230.154; 15.P.230.157; 15.P.230.166; 15.P.230.169; 15.P.230.172; 15.P.230.175; 15.P.230.240; 15.P.230.244; 15.P.231.228; 15.P.231.229; 15.P.231.230; 15.P.231.231; 15.P.231.236; 15.P.231.237; 15.P.231.238; 15.P.231.239; 15.P.231.154; 15.P.231.157; 15.P.231.166; 15.P.231.169; 15.P.231.172; 15.P.231.175; 15.P.231.240; 15.P.231.244; 15.P.236.228; 15.P.236.229; 15.P.236.230; 15.P.236.231; 15.P.236.236; 15.P.236.237; 15.P.236.238; 15.P.236.239; 15.P.236.154; 15.P.236.157; 15.P.236.166; 15.P.236.169; 15.P.236.172; 15.P.236.175; 15.P.236.240; 15.P.236.244; 15.P.237.228; 15.P.237.229; 15.P.237.230; 15.P.237.231; 15.P.237.236; 15.P.237.237; 15.P.237.238; 15.P.237.239; 15.P.237.154; 15.P.237.157; 15.P.237.166; 15.P.237.169; 15.P.237.172; 15.P.237.175; 15.P.237.240; 15.P.237.244; 15.P.238.228; 15.P.238.229; 15.P.238.230; 15.P.238.231; 15.P.238.236; 15.P.238.237; 15.P.238.238; 15.P.238.239; 15.P.238.154; 15.P.238.157; 15.P.238.166; 15.P.238.169; 15.P.238.172; 15.P.238.175; 15.P.238.240; 15.P.238.244; 15.P.239.228; 15.P.239.229; 15.P.239.230; 15.P.239.231; 15.P.239.236; 15.P.239.237; 15.P.239.238; 15.P.239.239; 15.P.239.154; 15.P.239.157; 15.P.239.166; 15.P.239.169; 15.P.239.172; 15.P.239.175; 15.P.239.240; 15.P.239.244; 15.P.154.228; 15.P.154.229; 15.P.154.230; 15.P.154.231; 15.P.154.236; 15.P.154.237; 15.P.154.238; 15.P.154.239; 15.P.154.154; 15.P.154.157; 15.P.154.166; 15.P.154.169; 15.P.154.172; 15.P.154.175; 15.P.154.240; 15.P.154.244; 15.P.157.228; 15.P.157.229; 15.P.157.230; 15.P.157.231; 15.P.157.236; 15.P.157.237; 15.P.157.238; 15.P.157.239; 15.P.157.154; 15.P.157.157; 15.P.157.166; 15.P.157.169; 15.P.157.172; 15.P.157.175; 15.P.157.240; 15.P.157.244; 15.P.166.228; 15.P.166.229; 15.P.166.230; 15.P.166.231; 15.P.166.236; 15.P.166.237; 15.P.166.238; 15.P.166.239; 15.P.166.154; 15.P.166.157; 15.P.166.166; 15.P.166.169; 15.P.166.172; 15.P.166.175; 15.P.166.240; 15.P.166.244; 15.P.169.228; 15.P.169.229; 15.P.169.230; 15.P.169.231; 15.P.169.236; 15.P.169.237; 15.P.169.238; 15.P.169.239; 15.P.169.154; 15.P.169.157; 15.P.169.166; 15.P.169.169; 15.P.169.172; 15.P.169.175; 15.P.169.240; 15.P.169.244; 15.P.172.228; 15.P.172.229; 15.P.172.230; 15.P.172.231; 15.P.172.236; 15.P.172.237; 15.P.172.238; 15.P.172.239; 15. P.172.154; 15.P.172.157; 15.P.172.166; 15.P.172.169; 15.P.172.172; 15.P.172.175; 15.P.172.240; 15.P.172.244; 15.P.175.228; 15.P.175.229; 15.P.175.230; 15.P.175.231; 15.P.175.236; 15.P.175.237; 15.P.175.238; 15.P.175.239; 15.P.175.154; 15.P.175.157; 15.P.175.166; 15.P.175.169; 15.P.175.172; 15.P.175.175; 15.P.175.240; 15.P.175.244; 15.P.240.228; 15.P.240.229; 15.P.240.230; 15.P.240.231; 15.P.24Q.236; 15.P.240.237; 15.P.240.238; 15.P.240.239; 15.P.240.154; 15.P.240.157; 15.P.240.166; 15.P.240.169; 15.P.240.172; 15.P.240.175; 15.P.240.240; 15.P.24Q.244; 15.P.244.228; 15.P.244.229; 15.P.244.230; 15.P.244.231; 15.P.244.236; 15.P.244.237; 15.P.244.238; 15.P.244.239; 15.P.244.154; 15.P.244.157; 15.P.244.166; 15.P.244.169; 15.P.244.172; 15.P.244.175; 15.P.244.240; 15.P.244.244;

Prodrugs of 15.U

15.U.228.228; 15.U.228.229; 15.U.228.230; 15.U.228.231; 15.U.228.236; 15.U.228.237; 15.U.228.238; 15.U.228.239; 15.U.228.154; 15.U.228.157; 15.U.228.166; 15.U.228.169; 15.U.228.172; 15.U.228.175; 15.U.228.240; 15.U.228.244; 15.U.229.228; 15.U.229.229; 15.U.229.230; 15.U.229.231; 15.U.229.236; 15.U.229.237; 15.U.229.238; 15.U.229.239; 15.U.229.154; 15.U.229.157; 15.U.229.166; 15.U.229.169; 15.U.229.172; 15.U.229.175; 15.U.229.240; 15.U.229.244; 15.U.230.228; 15.U.230.229; 15.U.230.230; 15.U.230.231; 15.U.230.236; 15.U.230.237; 15.U.230.238; 15.U.230.239; 15.U.230.154; 15.U.230.157; 15.U.230.166; 15.U.230.169; 15.U.230.172; 15.U.230.175; 15.U.230.240; 15.U.230.244; 15.U.231.228; 15.U.231.229; 15.U.231.230; 15.U.231.231; 15.U.231.236; 15.U.231.237; 15.U.231.238; 15.U.231.239; 15.U.231.154; 15.U.231.157; 15.U.231.166; 15.U.231.169; 15.U.231.172; 15.U.231.175; 15.U.231.240; 15.U.231.244; 15.U.236.228; 15.U.236.229; 15.U.236.230; 15.U.236.231; 15.U.236.236; 15.U.236.237; 15.U.236.238; 15.U.236.239; 15.U.236.154; 15.U.236.157; 15.U.236.166; 15.U.236.169; 15.U.236.172; 15.U.236.175; 15.IJ.236.240; 15.U.236.244; 15.U.237.228; 15.U.237.229; 15.U.237.230; 15.U.237.231; 15.U.237.236; 15.U.237.237; 15.U.237.238; 15.U.237.239; 15.U.237.154; 15.U.237.157; 15.U.237.166; 15.U.237.169; 15.U.237.172; 15.U.237.175; 15.U.237.240; 15.U.237.244; 15.U.238.228; 15.U.238.229; 15.U.238.230; 15.U.238.231; 15.U.238.236; 15.U.238.237; 15.U.238.238; 15.U.238.239; 15.U.238.154; 15.U.238.157; 15.U.238.166; 15.U.238.169; 15.U.238.172; 15.U.238.175; 15.U.238.240; 15.U.238.244; 15.U.239.228; 15.U.239.229; 15.U.239.230; 15.U.239.231; 15.U.239.236; 15.U.239.237; 15.U.239.238; 15.U.239.239; 15.U.239.154; 15.U.239.157; 15.U.239.166; 15.U.239.169; 15.U.239.172; 15.U.239.175; 15.U.239.240; 15.U.239.244; 15.U.154.228; 15.U.154.229; 15.U.154.230; 15.U.154.231; 15.U.154.236; 15.U.154.237; 15.U.154.238; 15.U.154.239; 15.U.154.154; 15.U.154.157; 15.U.154.166; 15.U.154.169; 15.U.154.172; 15.U.154.175; 15.U.154.240; 15.U.154.244; 15.U.157.228; 15.U.157.229; 15.U.157.230; 15.U.157.231; 15.U.157.236; 15.U.157.237; 15.U.157.238; 15.U.157.239; 15.U.157.154; 15. V.157.157} 15.U.157.166; 15.U.157.169; 15.U.157.172; 15.U.157.175; 15.U.157.240; 15.U.157.244; 15.U.166.228; 15.U.166.229; 15.U.166.230; 15.U.166.231; 15.U.166.236; 15.U.166.237; 15.U.166.238; 15.U.166.239; 15.U.166.154; 15.U.166.157; 15.U.166.166; 15.U.166.169; 15.U.166.172; 15.U.166.175; 15.U.166.240; 15.U.166.244; 15.U.169.228; 15.U.169.229; 15.U.169.230; 15.U.169.231; 15.U.169.236; 15.U.169.237; 15.U.169.238; 15.U.169.239; 15.U.169.154; 15.U.169.157; 15.U.169.166; 15.U.169.169; 15.U.169.172; 15.U.169.175; 15.U.169.240; 15.U.169.244; 15.U.172.228; 15.U.172.229; 15.U.172.230; 15.U.172.231; 15.U.172.236; 15.U.172.237; 15.U.172.238; 15.U.172.239; 15.U.172.154; 15.U.172.157; 15.U.172.166; 15.U.172.169; 15. V.172.172; 15.U.172.175; 15.U.172.240; 15.U.172.244; 15.U.175.228; 15.U.175.229; 15.U.175.230; 15.U.175.231; 15.U.175.236; 15.U.175.237; 15.U.175.238; 15.U.175.239; 15.U.175.154; 15.U.175.157; 15.U.175.166; 15.U.175.169; 15.U.175.172; 15.U.175.175; 15.U.175.240; 15.U.175.244; 15.U.240.228; 15.U.240.229; 15.U.240.230; 15.XJ.240.231; 15.U.240.236; 15.U.240.237; 15.U.240.238; 15.U.24Q.239; 15.U.240.154; 15.U.240.157; 15.U.24Q.166; 15.U.240.169; 15.U.240.172; 15.U.240.175; 15.U.240.240; 15.U.240.244; 15.U.244.228; 15.U.244.229; 15.U.244.230; 15.U.244.231; 15.U.244.236; 15.U.244.237; 15.U.244.238; 15.U.244.239; 15.U.244.154; 15.U.244.157; 15.U.244.166; 15.U.244.169; 15.U.244.172; 15.U.244.175; 15.U.244.240; 15.U.244.244;

Prodrugs of 15.CD

15.CD.228.228; 15.CD.228.229; 15.CD.228.230; 15.CD.228.231; 15.CD.228.236; 15.CD.228.237; 15.CD.228.238; 15.CD.228.239; 15.CD.228.154; 15.CD.228.157; 15.CD.228.166; 15.CD.228.169; 15.CD.228.172; 15.CD.228.175; 15.CD.228.240; 15.CD.228.244; 15.CD.229.228; 15.CD.229.229; 15.CD.229.230; 15.CD.229.231; 15.CD.229.236; 15.CD.229.237; 15.CD.229.238; 15.CD.229.239; 15.CD.229.154; 15.CD.229.157; 15.CD.229.166; 15.CD.229.169; 15.CD.229.172; 15.CD.229.175; 15.CD.229.240; 15.CD.229.244; 15.CD.230.228; 15.CD.230.229; 15.CD.230.230; 15.CD.230.231; 15.CD.230.236; 15.CD.230.237; 15.CD.230.238; 15.CD.230.239; 15.CD.230.154; 15.CD.230.157; 15.CD.230.166; 15.CD.230.169; 15.CD.230.172; 15.CD.230.175; 15.CD.230.240; 15.CD.230.244; 15.CD.231.228; 15.CD.231.229; 15.CD.231.230; 15.CD.231.231; 15.CD.231.236; 15.CD.231.237; 15.CD.231.238; 15.CD.231.239; 15.CD.231.154; 15.CD.231.157; 15.CD.231.166; 15.CD.231.169; 15.CD.231.172; 15.CD.231.175; 15.CD.231.240; 15.CD.231.244; 15.CD.236.228; 15.CD.236.229; 15.CD.236.230; 15.CD.236.231; 15.CD.236.236; 15.CD.236.237; 15.CD.236.238; 15.CD.236.239; 15.CD.236.154; 15.CD.236.157; 15.CD.236.166; 15.CD.236.169; 15.CD.236.172; 15.CD.236.175; 15.CD.236.240; 15.CD.236.244; 15.CD.237.228; 15.CD.237.229; 15.CD.237.230; 15.CD.237.231; 15.CD.237.236; 15.CD.237.237; 15.CD.237.238; 15.CD.237.239; 15.CD.237.154; 15.CD.237.157; 15.CD.237.166; 15.CD.237.169; 15.CD.237.172; 15.CD.237.175; 15.CD.237.240; 15.CD.237.244; 15.CD.238.228; 15.CD.238.229; 15.CD.238.230; 15.CD.238.231; 15.CD.238.236; 15.CD.238.237; 15.CD.238.238; 15.CD.238.239; 15.CD.238.154; 15.CD.238.157; 15.CD.238.166; 15.CD.238.169; 15.CD.238.172; 15.CD.238.175; 15.CD.238.240; 15.CD.238.244; 15.CD.239.228; 15.CD.239.229; 15.CD.239.230; 15.CD.239.231; 15.CD.239.236; 15.CD.239.237; 15.CD.239.238; 15.CD.239.239; 15.CD.239.154; 15.CD.239.157; 15.CD.239.166; 15.CD.239.169; 15.CD.239.172; 15.CD.239.175; 15.CD.239.240; 15.CD.239.244; 15.CD.154.228; 15.CD.154.229; 15.CD.154.230; 15.CD.154.231; 15.CD.154.236; 15.CD.154.237; 15.CD.154.238; 15.CD.154.239; 15.CD.154.154; 15.CD.154.157; 15.CD.154.166; 15.CD.154.169; 15.CD.154.172; 15.CP.154.175; 15.CD.154.240; 15.CD.154.244; 15.CD.157.228; 15.CD.157.229; 15.CD.157.230; 15.CD.157.231; 15.CD.157.236; 15.CD.157.237; 15.CD.157.238; 15.CD.157.239; 15.CD.157.154; 15.CD.157.157; 15.CD.157.166; 15.CD.157.169; 15.CD.157.172; 15.CD.157.175; 15.CD.157.240; 15.CD.157.244; 15.CD.166.228; 15.CD.166.229; 15.CD.166.230; 15.CD.166.231; 15.CD.166.236; 15.CD.166.237; 15.CD.166.238; 15.CD.166.239; 15.CD.166.154; 15.CD.166.157; 15.CD.166.166; 15.CD.166.169; 15.CD.166.172; 15.CD.166.175; 15.CD.166.240; 15.CD.166.244; 15.CD.169.228; 15.CD.169.229; 15.CD.169.230; 15.CD.169.231; 15.CD.169.236; 15.CD.169.237; 15.CD.169.238; 15.CD.169.239; 15.CD.169.154; 15.CD.169.157; 15.CD.169.166; 15.CD.169.169; 15.CD.169.172; 15.CD.169.175; 15.CD.169.240; 15.CD.169.244; 15.CD.172.228; 15.CD.172.229; 15.CD.172.230; 15.CD.172.231; 15.CD.172.236; 15.CD.172.237; 15.CD.172.238; 15. CD.172.239; 15.CD.172.154; 15.CD.172.157; 15.CD.172.166; 15.CD.172.169; 15. CD.172.172; 15.CD, 172.175; 15.CD.172.240; 15.CD.172.244; 15.CD.175.228; 15. CD.175.229; 15.CD.175.230; 15.CD.175.231; 15.CD.175.236; 15.CD.175.237; 15.CD.175.238; 15.CD.175.239; 15.CD.175.154; 15.CD.175.157; 15.CD.175.166; 15.CD.175.169; 15.CD.175.172; 15.CD.175.175; 15.CD.175.240; 15.CD.175.244; 15.CD.240.228; 15.CD.240.229; 15.CD.240.230; 15.CD.240.231; 15.CD.240.236; 15.CD.240.237; 15.CD.240.238; 15.CD.240.239; 15.CD.240.154; 15.CD.240.157; 15.CD.240.166; 15.CD.240.169; 15.CD.240.172; 15.CD.240.175; 15.CD.240.240; 15.CD.240.244; 15.CD.244.228; 15.CD.244.229; 15.CD.244.230; 15.CD.244.231; 15.CD.244.236; 15.CD.244.237; 15.CD.244.238; 15.CD.244.239; 15.CD.244.154; 15.CD.244.157; 15.CD.244.166; 15.CD.244.169; 15.CD.244.172; 15.CD.244.175; 15.CD.244.240; 15.CD.244.244;

Prodrugs of 15.EB

15.EB.228.228; 15.EB.228.229; 15.EB.228.230; 15.EB.228.231; 15.EB.228.236; 15.EB.228.237; 15.EB.228.238; 15.EB.228.239; 15.EB.228.154; 15.EB.228.157; 15.EB.228.166; 15.EB.228.169; 15.EB.228.172; 15.EB.228.175; 15.EB.228.240; 15.EB.228.244; 15.EB.229.228; 15.EB.229.229; 15.EB.229.230; 15.EB.229.231; 15.EB.229.236; 15.EB.229.237; 15.EB.229.238; 15.EB.229.239; 15.EB.229.154; 15.EB.229.157; 15.EB.229.166; 15.EB.229.169; 15.EB.229.172; 15.EB.229.175; 15.EB.229.240; 15.EB.229.244; 15.EB.230.228; 15.EB.230.229; 15.EB.230.230; 15.EB.230.231; 15.EB.230.236; 15.EB.230.237; 15.EB.230.238; 15.EB.230.239; 15.EB.230.154; 15.EB.230.157; 15.EB.230.166; 15.EB.230.169; 15.EB.230.172; 15.EB.230.175; 15.EB.230.240; 15.EB.230.244; 15.EB.231.228; 15.EB.231.229; 15.EB.231.230; 15.EB.231.231; 15.EB.231.236; 15.EB.231.237; 15.EB.231.238; 15.EB.231.239; 15.EB.231.154; 15.EB.231.157; 15.EB.231.166; 15.EB.231.169; 15.EB.231.172; 15.EB.231.175; 15.EB.231.240; 15.EB.231.244; 15.EB.236.228; 15.EB.236.229; 15.EB.236.230; 15.EB.236.231; 15.EB.236.236; 15.EB.236.237; 15.EB.236.238; 15.EB.236.239; 15.EB.236.154; 15.EB.236.157; 15.EB.236.166; 15.EB.236.169; 15.EB.236.172; 15.EB.236.175; 15.EB.236.240; 15.EB.236.244; 15.EB.237.228; 15.EB.237.229; 15.EB.237.230; 15.EB.237.231; 15.EB.237.236; 15.EB.237.237; 15.EB.237.238; 15.EB.237.239; 15.EB.237.154; 15.EB.237.157; 15.EB.237.166; 15.EB.237.169; 15.EB.237.172; 15.EB.237.175; 15. EB.237.240; 15.EB.237.244; 15.EB.238.228; 15.EB.238.229; 15.EB.238.230; 15.EB.238.231; 15.EB.238.236; 15.EB.238.237; 15.EB.238.238; 15.EB.238.239; 15.EB.238.154; 15.EB.238.157; 15.EB.238.166; 15.EB.238.169; 15.EB.238.172; 15.EB.238.175; 15.EB.238.240; 15.EB.238.244; 15.EB.239.228; 15.EB.239.229; 15.EB.239.230; 15.EB.239.231; 15.EB.239.236; 15.EB.239.237; 15.EB.239.238; 15.EB.239.239; 15.EB.239.154; 15.EB.239.157; 15.EB.239.166; 15.EB.239.169; 15.EB.239.172; 15.EB.239.175; 15.EB.239.240; 15.EB.239.244; 15.EB.154.228; 15.EB.154.229; 15.EB.154.230; 15.EB.154.231; 15.EB.154.236; 15.EB.154.237; 15.EB.154.238; 15.EB.154.239; 15.EB.154.154; 15.EB.154.157; 15.EB.154.166; 15.EB.154.169; 15.EB.154.172; 15.EB.154.175; 15.EB.154.240; 15.EB.154.244; 15.EB.157.228; 15.EB.157.229; 15.EB.157.230; 15.EB.157.231; 15.EB.157.236; 15.EB.157.237; 15.EB.157.238; 15.EB.157.239; 15.EB.157.154; 15.EB.157.157; 15.EB.157.166; 15.EB.157.169; 15.EB.157.172; 15.EB.157.175; 15.EB.157.240; 15.EB.157.244; 15.EB.166.228; 15.EB.166.229; 15.EB.166.230; 15.EB.166.231; 15.EB.166.236; 15.EB.166.237; 15.EB.166.238; 15.EB.166.239; 15.EB.166.154; 15.EB.166.157; 15.EB.166.166; 15.EB.166.169; 15.EB.166.172; 15.EB.166.175; 15.EB.166.240; 15.EB.166.244; 15.EB.169.228; 15.EB.169.229; 15.EB.169.230; 15.EB.169.231; 15.EB.169.236; 15.EB.169.237; 15.EB.169.238; 15.EB.169.239; 15.EB.169.154; 15.EB.169.157; 15.EB.169.166; 15.EB.169.169; 15.EB.169.172; 15.EB.169.175; 15.EB.169.240; 15.EB.169.244; 15.EB.172.228; 15.EB.172.229; 15.EB.172.230; 15.EB.172.231; 15.EB.172.236; 15.EB.172.237; 15.EB.172.238; 15.EB.172.239; 15.EB.172.154; 15.EB.172.157; 15.EB.172.166; 15.EB.172.169; 15.EB.172.172; 15.EB.172.175; 15.EB.172.240; 15.EB.172.244; 15. EB.175.228; 15.EB.175.229; 15.EB.175.230; 15.EB.175.231; 15.EB.175.236; 15.EB.175.237; 15.EB.175.238; 15.EB.175.239; 15.EB.175.154; 15.EB.175.157; 15.EB.175.166; 15.EB.175.169; 15.EB.175.172; 15.EB.175.175; 15.EB.175.240; 15.EB.175.244; 15.EB.240.228; 15.EB.240.229; 15.EB.240.230; 15.EB.240.231; 15.EB.240.236; 15. EB.240.237; 15.EB.240.238; 15.EB.240.239; 15.EB.240.154; 15.EB.240.157; 15.EB.240.166; 15.EB.240.169; 15. EB.240.172; 15.EB.240.175; 15.EB.240.240; 15.EB.240.244; 15.EB.244.228; 15.EB.244.229; 15. EB.244.230; 15.EB.244.231; 15.EB.244.236; 15.EB.244.237; 15.EB.244.238; 15.EB.244.239; 15.EB.244.154; 15.EB.244.157; 15.EB.244.166; 15. EB .244.169; 15.EB.244.172; 15.EB.244.175; 15.EB.244.240; 15.EB.244.244;

Prodrugs of 16.B

16.B.228.228; 16.B.228.229; 16.B.228.230; 16.B.228.231; 16.B.228.236; 16.B.228.237; 16.B.228.238; 16.B.228.239; 16.B.228.154; 16.B.228.157; 16.B.228.166; 16.B.228.169; 16.B.228.172; 16.B.228.175; 16.B.228.240; 16.B.228.244; 16.B.229.228; 16.B.229.229; 16.B.229.230; 16.B.229.231; 16.B.229.236; 16.B.229.237; 16.B.229.238; 16.B.229.239; 16.B.229.154; 16.B.229.157; 16.B.229.166; 16.B.229.169; 16.B.229.172; 16.B.229.175; 16.B.229.240; 16.B.229.244; 16.B.230.228; 16.B.230.229; 16.B.230.230; 16.B.230.231; 16.B.230.236; 16.B.230.237; 16.B.230.238; 16.B.230.239; 16.B.230.154; 16.B.230.157; 16.B.230.166; 16.B.230.169; 16.B.230.172; 16.B.230.175; 16.B.230.240; 16.B.230.244; 16.B.231.228; 16.B.231.229; 16.B.231.230; 16.B.231.231; 16.B.231.236; 16.B.231.237; 16.B.231.238; 16.B.231.239; 16.B.231.154; 16.B.231.157; 16.B.231.166; 16.B.231.169; 16.B.231.172; 16.B.231.175; 16.B.231.240; 16.B.231.244; 16.B.236.228; 16.B.236.229; 16.B.236.230; 16.B.236.231; 16.B.236.236; 16.B.236.237; 16.B.236.238; 16.B.236.239; 16.B.236.154; 16.B.236.157; 16.B.236.166; 16.B.236.169; 16.B.236.172; 16.B.236.175; 16.B.236.240; 16.B.236.244; 16.B.237.228; 16.B.237.229; 16.B.237.230; 16.B.237.231; 16.B.237.236; 16.B.237.237; 16.B.237.238; 16.B.237.239; 16.B.237.154; 16.B.237.157; 16.B.237.166; 16.B.237.169; 16.B.237.172; 16.B.237.175; 16.B.237.240; 16.B.237.244; 16.B.238.228; 16.B.238.229; 16.B.238.230; 16.B.238.231; 16.B.238.236; 16.B.238.237; 16.B.238.238; 16.B.238.239; 16.B.238.154; 16.B.238.157; 16.B.238.166; 16.B.238.169; 16.B.238.172; 16.B.238.175; 16.B.238.240; 16.B.238.244; 16.B.239.228; 16.B.239.229; 16.B.239.23Q; 16.B.239.231; 16.B.239.236; 16.B.239.237; 16.B.239.238; 16.B.239.239; 16.B.239.154; 16.B.239.157; 16.B.239.166; 16.B.239.169; 16.B.239.172; 16.B.239.175; 16.B.239.240; 16.B.239.244; 16.B.154.228; 16.B.154.229; 16.B.154.230; 16.B.154.231; 16.B.154.236; 16.B.154.237; 16.B.154.238; 16.B.154.239; 16.B.154.154; 16.B.154.157; 16.B.154.166; 16.B.154.169; 16.B.154.172; 16.B.154.175; 16.B.154.240; 16.B.154.244; 16.B.157.228; 16.B.157.229; 16.B.157.230; 16.B.157.231; 16.B.157.236; 16.B.157.237; 16.B.157.238; 16.B.157.239; 16.B.157.154; 16.B.157.157; 16.B.157.166; 16.B.157.169; 16.B.157.172; 16.B.157.175; 16.B.157.240; 16.B.157.244; 16.B.166.228; 16.B.166.229; 16.B.166.230; 16.B.166.231; 16.B.166.236; 16.B.166.237; 16.B.166.238; 16.B.166.239; 16.B.166.154; 16.B.166.157; 16.B.166.166; 16.B.166.169; 16.B.166.172; 16.B.166.175; 16.B.166.240; 16.B.166.244; 16.B.169.228; 16.B.169.229; 16.B.169.230; 16.B.169.231; 16.B.169.236; 16.B.169.237; 16.B.169.238; 16.B.169.239; 16.B.169.154; 16.B.169.157; 16.B.169.166; 16.B.169.169; 16.B.169.172; 16.B.169.175; 16.B.169.240; 16.B.169.244; 16.B.172.228; 16.B.172.229; 16.B.172.230; 16.B.172.231; 16.B.172.236; 16.B.172.237; 16.B.172.238; 16.B.172.239; 16.B.172.154; 16.B.172.157; 16.B.172.166; 16.B.172.169; 16.B.172.172; 16.B.172.175; 16.B.172.240; 16.B.172.244; 16.B.175.228; 16.B.175.229; 16.B.175.230; 16.B.175.231; 16.B.175.236; 16.B.175.237; 16.B.175-238; 16.B.175.239; 16.B.175.154; 16.B.175.157; 16.B.175.166; 16.B.175.169; 16.B.175.172; 16.B.175.175; 16.B.175.240; 16.B.175.244; 16.B.240.228; 16.B.240.229; 16.B.24Q.230; 16.B.240.231; 16.B.240.236; 16.B.240.237; 16.B.24Q.238; 16.B.240.239; 16.B.24Q.154; 16.B.240.157; 16.B.240.166; 16.B.240.169; 16.B.240.172; 16.B.240.175; 16.B.240.240; 16.B.240.244; 16.B.244.228; 16.B.244.229; 16.B.244.230; 16.B.244.231; 16.B.244.236; 16.B.244.237; 16.B.244.238; 16.B.244.239; 16.B.244.154; 16.B.244.157; 16.B.244.166; 16.B.244.169; 16.B.244.172; 16.B.244.175; 16.B.244.240; 16.B.244.244;

Prodrugs of 16.D

16.D.228.228; 16.D.228.229; 16.D.228.230; 16.D.228.231; 16.D.228.236; 16.D.228.237; 16.D.228.238; 16.D.228.239; 16.D.228.154; 16.D.228.157; 16.D.228.166; 16.D.228.169; 16.D.228.172; 16.D.228.175; 16.D.228.240; 16.D.228.244; 16.D.229.228; 16.D.229.229; 16.D.229.230; 16.D.229.231; 16.D.229.236; 16.D.229.237; 16.D.229.238; 16.D.229.239; 16.D.229.154; 16.D.229.157; 16.D.229.166; 16.D.229.169; 16.D.229.172; 16.D.229.175; 16.D.229.240; 16.D.229.244; 16.D.230.228; 16.D.230.229; 16.D.230.230; 16.D.230.231; 16.D.230.236; 16.D.230.237; 16.D.230.238; 16.D.230.239; 16.D.230.154; 16.D.230.157; 16.D.230.166; 16.D.23Q.169; 16.D.230.172; 16.D.230.175; 16.D.23Q.240; 16.D.230.244; 16.D.231.228; 16.D.231.229; 16.D.231.230; 16.D.231.231; 16.D.231.236; 16.D.231.237; 16.D.231.238; 16.D.231.239; 16.D.231.154; 16.D.231.157; 16.D.231.166; 16.D.231.169; 16.D.231.172; 16.D.231.175; 16.D.231.240; 16.D.231.244; 16.D.236.228; 16.D.236.229; 16.D.236.230; 16.D.236.231; 16.D.236.236; 16.D.236.237; 16.D.236.238; 16.D.236.239; 16.D.236.154; 16.D.236.157; 16.D.236.166; 16.D.236.169; 16.D.236.172; 16.D.236.175; 16.D.236.240; 16.D.236.244; 16.D.237.228; 16.D.237.229; 16.D.237.230; 16.D.237.231; 16.D.237.236; 16.D.237.237; 16.D.237.238; 16.D.237.239; 16.D.237.154; 16.D.237.157; 16.D.237.166; 16.D.237.169; 16.D.237.172; 16.D.237.175; 16.D.237.240; 16.D.237.244; 16.D.238.228; 16.D.238.229; 16.D.238.230; 16.D.238.231; 16.D.238.236; 16.D.238.237; 16.D.238.238; 16.D.238.239; 16.D.238.154; 16.D.238.157; 16.D.238.166; 16.D.238.169; 16.D.238.172; 16.D.238.175; 16.D.238.240; 16.D.238.244; 16.D.239.228; 16.D.239.229; 16.D.239.230; 16.D.239.231; 16.D.239.236; 16.D.239.237; 16.D.239.238; 16.D.239.239; 16.D.239.154; 16.D.239.157; 16.D.239.166; 16.D.239.169; 16.D.239.172; 16.D.239.175; 16.D.239.240; 16.D.239.244; 16.D.154.228; 16.D.154.229; 16.D.154.230; 16.D.154.231; 16.D.154.236; 16.D.154.237; 16.D.154.238; 16.D.154.239; 16.D.154.154; 16.D.154.157; 16.D.154.166; 16.D.154.169; 16.D.154.172; 16.D.154.175; 16.D.154.240; 16.D.154.244; 16.D.157.228; 16.D.157.229; 16.D.157.230; 16.D.157.231; 16.D.157.236; 16.D.157.237; 16.D.157.238; 16.D.157.239; 16.D.157.154; 16.D.157.157; 16.D.157.166; 16.D.157.169; 16.D.157.172; 16.D.157.175; 16.D.157.240; 16.D.157.244; 16.D.166.228; 16.D.166.229; 16.D.166.230; 16.D.166.231; 16.D.166.236; 16.D.166.237; 16.D.166.238; 16.D.166.239; 16.D.166.154; 16.D.166.157; 16.D.166.166; 16.D.166.169; 16.D.166.172; 16.D.166.175; 16.D.166.240; 16.D.166.244; 16.D.169.228; 16.D.169.229; 16.D.169.230; 16.D.169.231; 16.D.169.236; 16.D.169.237; 16.D.169.238; 16.D.169.239; 16.D.169.154; 16.D.169.157; 16.D.169.166; 16.D.169.169; 16.D.169.172; 16.D.169.175; 16.D.169.240; 16.D.169.244; 16.D.172.228; 16.D.172.229; 16.D.172.230; 16.D.172.231; 16.D.172.236; 16.D.172.237; 16.D.172.238; 16.D.172.239; 16.D.172.154; 16.D.172.157; 16.D.172.166; 16.D.172.169; 16.D.172.172; 16.D.172.175; 16.D.172.240; 16.D.172.244; 16.D.175.228; 16.D.175.229; 16.D.175.230; 16.D.175.231; 16.D.175.236; 16.D.175.237; 16.D.175.238; 16.D.175.239; 16.D.175.154; 16.D.175.157; 16.D.175.166; 16.D.175.169; 16.D.175.172; 16.D.175.175; 16.D.175.240; 16.D.175.244; 16.D.240.228; 16.D.240.229; 16.D.240.230; 16.D.240.231; 16.D.240.236; 16.D.240.237; 16.D.240.238; 16.D.240.239; 16.D.240.154; 16.D.240.157; 16.D.240.166; 16.D.240.169; 16.D.240.172; 16.D.240.175; 16.D.240.240; 16.D.240.244; 16.D.244.228; 16.D.244.229; 16.D.244.230; 16.D.244.231; 16.D.244.236; 16.D.244.237; 16.D.244.238; 16.D.244.239; 16.D.244.154; 16.D.244.157; 16.D.244.166; 16.D.244.169; 16.D.244.172; 16.D.244.175; 16.D.244.240; 16.D.244.244; Prodrugs of 16.AB

16.AB.228.228; 16.AB.228.229; 16.AB.228.230; 16.AB.228.231; 16.AB.228.236; 16.AB.228.237; 16.AB.228.238; 16.AB.228.239; 16.AB.228.154; 16.AB.228.157; 16.AB.228.166; 16.AB.228.169; 16.AB.228.172; 16.AB.228.175; 16.AB.228.240; 16.AB.228.244; 16.AB.229.228; 16.AB.229.229; 16.AB.229.230; 16.AB.229.231; 16.AB.229.236; 16.AB.229.237; 16.AB.229.238; 16.AB.229.239; 16. AB.229.154; 16.AB.229.157; 16.AB.229.166; 16.AB.229.169; 16.AB.229.172; 16.AB.229.175; 16.AB.229.240; 16.AB.229.244; 16.AB.230.228; 16.AB.230.229; 16.AB.230.230; 16.AB.230.231; 16.AB.230.236; 16.AB.230.237; 16.AB.230.238; 16.AB.230.239; 16.AB.230.154; 16.AB.230.157; 16.AB.230.166; 16.AB.23Q.169; 16.AB.230.172; 16.AB.230.175; 16.AB.230.240; 16.AB.230.244; 16.AB.231.228; 16.AB.231.229; 16.AB.231.230; 16.AB.231.231; 16.AB.231.236; 16.AB.231.237; 16.AB.231.238; 16.AB.231.239; 16.AB.231.154; 16.AB.231.157; 16.AB.231.166; 16.AB.231.169; 16.AB.231.172; 16.AB.231.175; 16.AB.231.240; 16.AB.231.244; 16.AB.236.228; 16.AB.236.229; 16.AB.236.23Q; 16.AB.236.231; 16.AB.236.236; 16.AB.236.237; 16.AB.236.238; 16.AB.236.239; 16.AB.236.154; 16.AB.236.157; 16.AB.236.166; 16.AB.236.169; 16.AB.236.172; 16.AB.236.175; 16.AB.236.240; 16.AB.236.244; 16.AB.237.228; 16. AB.237.229; 16.AB.237.23Q; 16.AB.237.231; 16.AB.237.236; 16.AB.237.237; 16.AB.237.238; 16.AB.237.239; 16.AB.237.154; 16.AB.237.157; 16.AB.237.166; 16.AB.237.169; 16.AB.237.172; 16.AB.237.175; 16.AB.237.240; 16.AB.237.244; 16.AB.238.228; 16.AB.238.229; 16.AB.238.230; 16.AB.238.231; 16.AB.238.236; 16.AB.238.237; 16.AB.238.238; 16.AB.238.239; 16.AB.238.154; 16.AB.238.157; 16.AB.238.166; 16.AB.238.169; 16.AB.238.172; 16.AB.238.175; 16.AB.238.240; 16.AB.238.244; 16.AB.239.228; 16.AB.239.229; 16. AB.239.230; 16.AB.239.231; 16.AB.239.236; 16.AB.239.237; 16.AB.239.238; 16.AB.239.239; 16.AB.239.154; 16.AB.239.157; 16.AB.239.166; 16.AB.239.169; 16. AB.239.172; 16.AB.239.175; 16.AB.239.240; 16.AB.239.244; 16.AB.154.228; 16.AB.154.229; 16.AB.154.230; 16.AB.154.231; 16.AB.154.236; 16.AB.154.237; 16.AB.154.238; 16.AB.154.239; 16.AB.154.154; 16.AB.154.157; 16.AB.154.166; 16.AB.154.169; 16.AB.154.172; 16.AB.154.175; 16.AB.154.240; 16.AB.154.244; 16.AB.157.228; 16.AB.157.229; 16.AB.157.230; 16.AB.157.231; 16.AB.157.236; 16.AB.157.237; 16.AB.157.238; 16.AB.157.239; 16.AB.157.154; 16.AB.157.157; 16.AB.157.166; 16.AB.157.169; 16.AB.157.172; 16.AB.157.175; 16.AB.157.240; 16.AB.157.244; 16.AB.166.228; 16.AB.166.229; 16.AB.166.230; 16.AB.166.231; 16.AB.166.236; 16.AB.166.237; 16.AB.166.238; 16.AB.166.239; 16-AB.166.154; 16.AB.166.157; 16.AB.166.166; 16.AB.166.169; 16.AB.166.172; 16.AB.166.175; 16.AB.166.240; 16.AB.166.244; 16.AB.169.228; 16.AB.169.229; 16.AB.169.230; 16.AB.169.231; 16.AB.169.236; 16.AB.169.237; 16.AB.169.238; 16.AB.169.239; 16.AB.169.154; 16.AB.169.157; 16.AB.169.166; 16.AB.169.169; 16.AB.169.172; 16.AB.169.175; 16.AB.169.240; 16.AB.169.244; 16.AB.172.228; 16.AB.172.229; 16.AB.172.230; 16.AB.172.231; 16.AB.172.236; 16.AB.172.237; 16.AB.172.238; 16.AB.172.239; 16.AB.172.154; 16.AB.172.157; 16.AB.172.166; 16.AB.172.169; 16.AB.172.172; 16.AB.172.175; 16.AB.172.240; 16.AB.172.244; 16.AB.175.228; 16. AB.175.229; 16.AB.175.230; 16.AB.175.231; 16.AB.175.236; 16.AB.175.237; 16.AB.175.238; 16.AB.175.239; 16.AB.175.154; 16.AB.175.157; 16.AB.175.166; 16.AB.175.169; 16.AB.175.172; 16.AB.175.175; 16. AB.175.240; 16.AB.175.244; 16.AB.240.228; 16.AB.240.229; 16.AB.240.230; 16.AB.240.231; 16.AB.240.236; 16.AB.240.237; 16.AB.240.238; 16. AB.240.239; 16.AB.240.154; 16.AB.240.157; 16.AB.240.166; 16.AB.240.169; 16.AB.240.172; 16.AB.240.175; 16. AB .240.240; 16.AB.240.244; 16.AB.244.228; 16.AB.244.229; 16.AB.244.230; 16.AB.244.231; 16.AB.244.236; 16.AB.244.237; 16.AB.244.238; 16.AB.244.239; 16.AB.244.154; 16.AB.244.157; 16.AB.244.166; 16.AB.244.169; 16.AB.244.172; 16.AB.244.175; 16.AB.244.240; 16.AB.244.244;

Prodrugs of 16.BI

16.BI.228.228; 16.BI.228.229; 16.BI.228.230; 16.BI.228.231; 16.BI.228.236; 16.BI.228.237; 16.BI.228.238; 16.BI.228.239; 16.BI.228.154; 16.BI.228.157; 16.BI.228.166; 16.BI.228.169; 16.BI.228.172; 16.BI.228.175; 16.BI.228.240; 16.BI.228.244; 16.BI.229.228; 16.BI.229.229; 16.BL229.230; 16.BI.229.231; 16.BI.229.236; 16.BI.229.237; 16.BI.229.238; 16.BI.229.239; 16.BI.229.154; 16.BI.229.157; 16.BI.229.166; 16.BI.229.169; 16.BI.229.172; 16.BI.229.175; 16.BI.229.240; 16.BI.229.244; 16.BI.230.228; 16.BI.230.229; 16.BI.230.230; 16.BI.230.231; 16.BI.230.236; 16.BI.230.237; 16.BI.230.238; 16.BI.230.239; 16.BI.230.154; 16.BI.230.157; 16.BI.230.166; 16.BL230.169; 16.BI.230.172; 16.BI.230.175; 16.BI.230.240; 16.BI.230.244; 16.BI.231.228; 16.BI.231.229; 16.BI.231.230; 16.BI.231.231; 16.BI.231.236; 16.BI.231.237; 16.BI.231.238; 16.BI.231.239; 16.BI.231.154; 16.BI.231.157; 16.BI.231.166; 16.BI.231.169; 16.BI.231.172; 16.BI.231.175; 16.BI.231.240; 16.BI.231.244; 16.BI.236.228; 16.BI.236.229; 16.BI.236.230; 16.BI.236.231; 16.BI.236.236; 16.BI.236.237; 16.BI.236.238; 16.BI.236.239; 16.BI.236.154; 16.BI.236.157; 16.BI.236.166; 16.BI.236.169; 16.BI.236.172; 16.BI.236.175; 16.BI.236.240; 16.BI.236.244; 16.BI.237.228; 16.BI.237.229; 16.BI.237.230; 16.BI.237.231; 16.BI.237.236; 16.BI.237.237; 16.BI.237.238; 16.BI.237.239; 16.BI.237.154; 16.BI.237.157; 16.BI.237.166; 16.BI.237.169; 16.BI.237.172; 16.BI.237.175; 16.BI.237.240; 16.BI.237.244; 16.BI.238.228; 16.BI.238.229; 16.BI.238.230; 16.BI.238.231; 16.BI.238.236; 16.BI.238.237; 16.BI.238.238; 16.BI.238.239; 16.BI.238.154; 16.BI.238.157; 16.BI.238.166; 16.BI.238.169; 16.BI.238.172; 16.BI.238.175; 16.BI.238.240; 16.BI.238.244; 16.BI.239.228; 16.BI.239.229; 16.BI.239.230; 16.BI.239.231; 16.BI.239.236; 16.BI.239.237; 16.BI.239.238; 16.BI.239.239; 16.BI.239.154; 16.BI.239.157; 16.BI.239.166; 16.BI.239.169; 16.BI.239.172; 16.BI.239.175; 16.BI.239.240; 16.BI.239.244; 16.BI.154.228; 16.BI.154.229; 16.BI.154.230; 16.BI.154.231; 16.BI.154.236; 16.BI.154.237; 16.BI.154.238; 16.BI.154.239; 16.BI.154.154; 16.BI.154.157; 16.BI.154.166; 16.BI.154.169; 16.BI.154.172; 16.BI.154.175; 16.BI.154.240; 16.BI.154.244; 16.BI.157.228; 16.BI.157.229; 16.BI.157.230; 16.BI.157.231; 16.BL157.236; 16.BI.157.237; 16.BI.157.238; 16.BI.157.239; 16.BI.157.154; 16.BI.157.157; 16.BI.157.166; 16.BI.157.169; 16.BI.157.172; 16.BL157.175; 16.BI.157.240; 16.BI.157.244; 16.BI.166.228; 16.BI.166.229; 16.BI.166.230; 16.BI.166.231; 16.BI.166.236; 16.BI.166.237; 16.BI.166.238; 16.BI.166.239; 16.BI.166.154; 16.BI.166.157; 16.BI.166.166; 16.BI.166.169; 16.BI.166.172; 16.BI.166.175; 16.BI.166.240; 16.BI.166.244; 16.BI.169.228; 16.BI.169.229; 16.BI.169.230; 16.BI.169.231; 16.BI.169.236; 16.BI.169.237; 16.BI.169.238; 16.BI.169.239; 16.BI.169.154; 16.BI.169.157; 16.BI.169.166; 16.BL169.169; 16.BI.169.172; 16.BI.169.175; 16.BI.169.240; 16.BI.169.244; 16.BI.172.228; 16.BI.172.229; 16.BI.172.230; 16.BI.172.231; 16.BI.172.236; 16.BI.172.237; 16.BI.172.238; 16.BI.172.239; 16.BI.172.154; 16.BI.172.157; 16.BI.172.166; 16.BI.172.169; 16.BI.172.172; 16.BI.172.175; 16.BI.172.240; 16.BI.172.244; 16.BI.175.228; 16.BI.175.229; 16.BI.175.230; 16.BI.175.231; 16.BI.175.236; 16.BI.175.237; 16.BI.175.238; 16.BI.175.239; 16.BI.175.154; 16.BI.175.157; 16.BI.175.166; 16.BI.175.169; 16.BI.175.172; 16.BI.175.175; 16.BI.175.240; 16.BI.175.244; 16.BI.240.228; 16.BI.240.229; 16.BI.240.230; 16.BI.240.231; 16.BI.240.236; 16.BI.240.237; 16.BI.240.238; 16.BI.240-239; 16.BI.240.154; 16.BI.240.157; 16.BI.240.166; 16.BI.240.169; 16.BI.240.172; 16.BI.240.175; 16.BI.240.240; 16.BI.240.244; 16.BI.244.228; 16.BI.244.229; 16.BI.244.230; 16.BI.244.231; 16.BI.244.236; 16.BI.244.237; 16.BI.244.238; 16.BI.244.239; 16.BI.244.154; 16.BI.244.157; 16.BI.244.166; 16.BI.244.169; 16.BI.244.172; 16.BI.244.175; 16.BI.244.240; 16.BI.244.244;

Prodrugs of 16.1

16.1.228.228; 16.1.228.229; 16.1.228.230; 16.1.228.231; 16.1.228.236; 16.1.228.237; 16.1.228.238; 16.1.228.239; 16.1.228.154; 16.1.228.157; 16.1.228.166; 16.1.228.169; 16.1.228.172; 16.1.228.175; 16.1.228.240; 16.1.228.244; 16.1.229.228; 16.1.229.229; 16.1.229.230; 16.1.229.231; 16.1.229.236; 16.1.229.237; 16.1.229.238; 16.1.229.239; 16.1.229.154; 16.1.229.157; 16.1.229.166; 16.1.229.169; 16.1.229.172; 16.1.229.175; 16.1.229.240; 16.1.229.244; 16.1.230.228; 16.1.230.229; 16.1.230.230; 16.1.230.231; 16.1.230.236; 16.1.230.237; 16.1.230.238; 16.1.230.239; 16.1.230.154; 16.1.230.157; 16.1.230.166; 16.1.230.169; 16.1.230.172; 16.1.230.175; 16.1.230.240; 16.1.230.244; 16.1.231.228; 16.1.231.229; 16.1.231.230; 16.1.231.231; 16.1.231.236; 16.1.231.237; 16.1.231.238; 16.1.231.239; 16.1.231.154; 16.1.231.157; 16.1.231.166; 16.1.231.169; 16.1.231.172; 16.1.231.175; 16.1.231.240; 16.1.231.244; 16.1.236.228; 16.1.236.229; 16.1.236.230; 16.1.236.231; 16.1.236.236; 16.1.236.237; 16.1.236.238; 16.1.236.239; 16.1.236.154; 16.1.236.157; 16.1.236.166; 16.1.236.169; 16.1.236.172; 16.1.236.175; 16.1.236.240; 16.1.236.244; 16.1.237.228; 16.1.237.229; 16.1.237.230; 16.1.237.231; 16.1.237.236; 16.1.237.237; 16.1.237.238; 16.1.237.239; 16.1.237.154; 16.1.237.157; 16.1.237.166; 16.1.237.169; 16.1.237.172; 16.1.237.175; 16.1.237.240; 16.1.237.244; 16.1.238.228; 16.1.238.229; 16.1.238.230; 16.1.238.231; 16.1.238.236; 16.1.238.237; 16.1.238.238; 16.1.238.239; 16.1.238.154; 16.1.238.157; 16.1.238.166; 16.1.238.169; 16.1.238.172; 16.1.238.175; 16.1.238.240; 16.1.238.244; 16.1.239.228; 16.1.239.229; 16.1.239.230; 16.1.239.231; 16.1.239.236; 16.1.239.237; 16.1.239.238; 16.1.239.239; 16.1.239.154; 16.1.239.157; 16.1.239.166; 16.1.239.169; 16.1.239.172; 161.239.175; 16.1.239.240; 16.1.239.244; 16.1.154.228; 16.1.154.229; 16.1.154.230; 16.1.154.231; 16.1.154.236; 16.1.154.237; 16.1.154.238; 16.1.154.239; 16.1.154.154; 16.1.154.157; 16.1.154.166; 16.1.154.169; 16.1.154.172; 16.1.154.175; 16.1.154.240; 16.1.154.244; 16.1.157.228; 16.1.157.229; 16.1.157.230; 16.1.157.231; 16.1.157.236; 16.1.157.237; 16.1.157.238; 16.1.157.239; 16.1.157.154; 16.1.157.157; 16.1.157.166; 16.1.157.169; 16.1.157.172; 16.1.157.175; 16.1.157.240; 16.1.157.244; 16.1.166.228; 16.1.166.229; 16.1.166.230; 16.1.166.231; 16.1.166.236; 16.1.166.237; 16.1.166.238; 16.1.166.239; 16.1.166.154; 16.1.166.157; 16.1.166.166; 16.1.166.169; 16.1.166.172; 16.1.166.175; 16.1.166.240; 16.1.166.244; 16.1.169.228; 16.1.169.229; 16.1.169.230; 16.1.169.231; 16.1.169.236; 16.1.169.237; 16.1.169.238; 16.1.169.239; 16.1.169.154; 16.1.169.157; 16.1.169.166; 16.1.169.169; 16.1.169.172; 16.1.169.175; 16.1.169.240; 16.1.169.244; 16.1.172.228; 16.1.172.229; 16.1.172.230; 16.1.172.231; 16.1.172.236; 16.1.172.237; 16.1.172.238; 16.1.172.239; 16.1.172.154; 16.1.172.157; 16.1.172.166; 16.1.172.169; 16.1.172.172; 16.1.172.175; 16.1.172.240; 16.1.172.244; 16.1.175.228; 16.1.175.229; 16.1.175.230; 16.1.175.231; 16.1.175.236; 16.1.175.237; 16.1.175.238; 16.1.175.239; 16.1.175.154; 16.1.175.157; 16.1.175.166; 16.1.175.169; 16.1.175.172; 16.1.175.175; 16.1.175.240; 16.1.175.244; 16.1.240.228; 16.1.240.229; 16.1.240.230; 16.1.240.231; 16.1.240.236; 16.1.240.237; 16.1.240.238; 16.1.240-239; 16.1.240.154; 16.1.240.157; 16.1.240.166; 16.1.240.169; 16.1.240.172; 16.1.240.175; 16.1.240.240; 16.1.240.244; 16.L244.228; 16.1.244.229; 16.1.244.230; 16.1.244.231; 16.1.244.236; 16.1.244.237; 16.1.244.238; 16.1.244.239; 16.1.244.154; 16.1.244.157; 16.1.244.166; 16.1.244.169; 16.1.244.172; 16.1.244.175; 16.1.244.240; 16.1.244.244;

Prodrugs of 16.T

16.J.228.228; 16.J.228.229; 16.J.228.230; 16J.228.231; 16.J.228.236; 16.J.228.237; 16.J.228.238; 16.J.228.239; 16.J.228.154; 16.J.228.157; 16.J.228.166; 16.J.228.169; 16.J.228.172; 16.J.228.175; 16.J.228.240; 16.J.228.244; 16.J.229.228; 16.J.229.229; 16.J.229.230; 16.J.229.231; 16.J.229.236; 16.J.229.237; 16.J.229.238; 16.J.229.239; 16.J.229.154; 16.J.229.157; 16.J.229.166; 16.J.229.169; 16.J.229.172; 16.J.229.175; 16.J.229.240; 16.J.229.244; 16.J.230.228; 16.J.230.229; 16.J.230.23Q; 16.J.230.231; 16.J.230.236; 16.J.230.237; 16.J.230.238; 16.J.230.239; 16.J.230.154; 16.J.230.157; 16.J.230.166; 16.J.230.169; 16.J.230.172; 16.J.230.175; 16.J.230.240; 16.J.230.244; 16J.231.228; 16J.231.229; 16J.231.230; 16J.231.231; 16J.231.236; 16J.231.237; 16J.231.238; 16J.231.239; 16J.231.154; 16J.231.157; 16J.231.166; 16J.231.169; 16J.231.172; 16J.231.175; 16J.231.240; 16J.231.244; 16.J.236.228; 16J.236.229; 16.J.236.230; 16J.236.231; 16.J.236.236; 16.J.236.237; 16.J.236.238; 16J.236.239; 16.J.236.154; 16.J.236.157; 16.J.236.166; 16.J.236.169; 16.J.236.172; 16.J.236.175; 16.J.236.240; 16.J.236.244; 16.J.237.228; 16.J.237.229; 16.J.237.230; 16J.237.231; 16.J.237.236; 16.J.237.237; 16.J.237.238; 16.J.237.239; 16J.237.154; 16.J.237.157; 16.J.237.166; 16.J.237.169; 16.J.237.172; 16.J.237.175; 16.J.237.240; 16.J.237.244; 16.J.238.228; 16.J.238.229; 16.J.238.230; 16 J.238.231; 16.J.238.236; 16.J.238.237; 16.J.238.238; 16.J.238.239; 16.J.238.154; 16.J.238.157; 16J.238.166; 16.J.238.169; 16.J.238.172; 16J.238.175; 16.J.238.240; 16.J.238.244; 16.J.239.228; 16.J.239.229; 16J.239.230; 16J.239.231; 16.J.239.236; 16.J.239.237; 16.J.239.238; 16.J.239.239; 16.J.239.154; 16J.239.157; 16.J.239.166; 16.J.239.169; 16.J.239.172; 16.J.239.175; 16.J.239.240; 16.J.239.244; 16.J.154.228; 16J.154.229; 16.J.154.230; 16J.154.231; 16.J.154.236; 16.J.154.237; 16J.154.238; 16.J.154.239; 16J.154.154; 16J.154.157; 16J.154.166; 16J.154.169; 16J.154.172; 16J.154.175; 16J.154.240; 16.J.154.244; 16.J.157.228; 16J.157.229; 16.J.157.230; 16J.157.231; 16J.157.236; 16.J.157.237; 16.J.157.238; 16.J.157.239; 16J.157.154; 16J.157.157; 16 J.157.166; 16J.157.169; 16J.157.172; 16 J.157.175; 16.J.157.240; 16.J.157.244; 16.J.166.228; 16.J.166.229; 16.J.166.230; 16 J.166.231; 16.J.166.236; 16.J.166.237; 16.J.166.238; 16.J.166.239; 16J.166.154; 16J.166.157; 16J.166.166; 16J.166.169; 16J.166.172; 16J.166.175; 16.J.166.240; 16.J.166.244; 16.J.169.228; 16J.169.229; 16J.169.230; 16J.169.231; 16.J.169.236; 16.J.169.237; 16.J.169.238; 16.J.169.239; 16J.169.154; 16J.169.157; 16J.169.166; 16J.169.169; 16J.169.172; 16J.169.175; 16J.169.240; 16J.169.244; 16J.172.228; 16J.172.229; 16J.172.230; 16J.172.231; 16J.172.236; 16J.172.237; 16J.172.238; 16J.172.239; 16J.172.154; 16J.172.157; 16J.172.166; 16J.172.169; 16J.172.172; 16 J.172.175; 16J.172.240; 16J.172.244; 16J.175.228; 16.J.175.229; 16J.175.230; 16J.175.231; 16J.175.236; 16J.175.237; 16J.175.238; 16J.175.239; 16J.175.154; 16J.175.157; 16J.175.166; 16J.175.169; 16J.175.172; 16J.175.175; 16J.175.240; 16J.175.244; 16J.240.228; 16J.240.229; 16J.240.230; 16 J.240.231; 16J.240.236; 16J.240.237; 16J.240.238; 16J.240.239; 16J.240.154; 16J.240.157; 16J.240.166; 16J.240.169; 16J.240.172; 16J.240.175; 16J.240.240; 16J.240.244; 16J.244.228; 16J.244.229; 16J.244.230; 16J.244.231; 16J.244.236; 16 J.244.237; 16J.244.238; 16J.244.239; 16J.244.154; 16J.244.157; 16J.244.166; 16J.244.169; 16J.244.172; 16J.244.175; 16.J.244.240; 16.J.244.244;

Prodrugs of 16.L

16.L.228.228; 16.L.228.229; 16.L.228.230; 16.L.228.231; 16.L.228.236; 16.L.228.237; 16.L.228.238; 16.L.228.239; 16.L.228.154; 16.L.228.157; 16.L.228.166; 16.L.228.169; 16.L.228.172; 16.L.228.175; 16.L.228.240; 16.L.228.244; 16.L.229.228; 16.L.229.229; 16.L.229.230; 16.L.229.231; 16.L.229.236; 16.L.229.237; 16.L.229.238; 16.L.229.239; 16.L.229.154; 16.L.229.157; 16.L.229.166; 16.L.229.169; 16.L.229.172; 16.L.229.175; 16.L.229.240; 16.L.229.244; 16.L.230.228; 16.L.230.229; 16.L.230.230; 16.L.230.231; 16.L.230.236; 16.L.230.237; 16.L.230.238; 16.L.230.239; 16.L.230.154; 16.L.230.157; 16.L.230.166; 16.L.230.169; 16.L.230.172; 16.L.230.175; 16.L.230.240; 16.L.230.244; 16.L.231.228; 16.L.231.229; 16.L.231.230; 16.L.231.231; 16.L.231.236; 16.L.231.237; 16.L.231.238; 16.L.231.239; 16.L.231.154; 16.L.231.157; 16.L.231.166; 16.L.231.169; 16.L.231.172; 16.L.231.175; 16.L.231.24Q; 16.L.231.244; 16.L.236.228; 16.L.236.229; 16.L.236.230; 16.L.236.231; 16.L.236.236; 16.L.236.237; 16.L.236.238; 16.L.236.239; 16.L.236.154; 16.L.236.157; 16.L.236.166; 16.L.236.169; 16.L.236.172; 16.L.236.175; 16.L.236.240; 16.L.236.244; 16.L.237.228; 16.L.237.229; 16.L.237.230; 16.L.237.231; 16.L.237.236; 16.L.237.237; 16.L.237.238; 16.L.237.239; 16.L.237.154; 16.L.237.157; 16.L.237.166; 16.L.237.169; 16.L.237.172; 16.L.237.175; 16.L.237.240; 16.L.237.244; 16.L.238.228; 16.L.238.229; 16.L.238.230; 16.L.238.231; 16.L.238.236; 16.L.238.237; 16.L.238.238; 16.L.238.239; 16.L.238.154; 16.L.238.157; 16.L.238.166; 16.L.238.169; Ϊ6.L.238.172; 16.L.238.175; 16.L.238.240; 16.L.238.244; 16.L.239.228; 16.L.239.229; 16.L.239.230; 16.L.239.231; 16-L.239.236; 16.L.239.237; 16.L.239.238; 16.L.239.239; 16.L.239.154; 16.L.239.157; 16.L.239.166; 16.L.239.169; 16.L.239.172; 16.L.239.175; 16.L.239.240; 16.L.239.244; 16.L.154.228; 16.L.154.229; 16.L.154.230; 16.L.154.231; 16.L.154.236; 16.L.154.237; 16.L.154.238; 16.L.154.239; 16.L.154.154; 16.L.154.157; 16.L.154.166; 16.L.154.169; 16.L.154.172; 16.L.154.175; 16.L.154.240; 16.L.154.244; 16.L.157.228; 16.L.157.229; 16.L.157.230; 16.L.157.231; 16.L.157.236; 16.L.157.237; 16.L.157.238; 16.L.157.239; 16.L.157.154; 16.L.157.157; 16.L.157.166; 16.L.157.169; 16.L.157.172; 16.L.157.175; 16.L.157.240; 16.L.157.244; 16.L.166.228; 16.L.166.229; 16.L.166.230; 16.L.166.231; 16.L.166.236; 16.L.166.237; 16.L.166.238; 16.L.166.239; 16.L.166.154; 16.L.166.157; 16.L.166.166; 16.L.166.169; 16.L.166.172; 16.L.166.175; 16.L.166.240; 16.L.166.244; 16.L.169.228; 16.L.169.229; 16.L.169.230; 16.L.169.231; 16.L.169.236; 16.L.169.237; 16.L.169.238; 16.L.169.239; 16.L.169.154; 16.L.169.157; 16.L.169.166; 16.L.169.169; 16.L.169.172; 16.L.169.175; 16.L.169.240; 16.L.169.244; 16.L.172.228; 16.L.172.229; 16.L.172.230; 16.L.172.231; 16.L.172.236; 16.L.172.237; 16.L.172.238; 16.L.172.239; 16.L.172.154; 16.L.172.157; 16.L.172.166; 16.L.172.169; 16.L.172.172; 16.L.172.175; 16.L.172.240; 16.L.172.244; 16.L.175.228; 16.L.175.229; 16.L.175.230; 16.L.175.231; 16.L.175.236; 16.L.175.237; 16.L.175.238; 16.L.175.239; 16.L.175.154; 16.L.175.157; 16.L.175.166; 16.L.175.169; 16.L.175.172; 16.L.175.175; 16.L.175.240; 16.L.175.244; 16.L.240.228; 16.L.240.229; 16.L.240.230; 16.L.240.231; 16.L.240.236; 16.L.240.237; 16.L.24Q.238; 16.L.240.239; 16.L.240.154; 16.L.240.157; 16.L.240.166; 16.L.240.169; 16.L.240.172; 16.L.240.175; 16.L.240.240; 16.L.240.244; 16.L.244.228; 16.L.244.229; 16.L.244.230; 16.L.244.231; 16.L.244.236; 16.L.244.237; 16.L.244.238; 16.L.244.239; 16.L.244.154; 16.L.244.157; 16.L.244.166; 16.L.244.169; 16.L.244.172; 16.L.244.175; 16.L.244.240; 16.L.244.244;

Prodrugs of 16.O

16.O.228.228; 16.O.228.229; 16.O.228.230; 16.O.228.231; 16.O.228.236; 16.O.228.237; 16.O.228.238; 16.0.228.239; 16.O.228.154; 16.O.228.157; 16.O.228.166; 16.O.228.169; 16.O.228.172; 16.O.228.175; 16.O.228.240; 16.O.228.244; 16.O.229.228; 16.O.229.229; 16.O.229.230; 16.O.229.231; 16.O-229.236; 16.O.229.237; 16.O.229.238; 16.O.229.239; 16.O.229.154; 16.O.229.157; 16.O.229.166; 16.O-229.169; 16.O.229.172; 16.O.229.175; 16.O.229.240; 16.O.229.244; 16.O.230-228; 16.O.230.229; 16.O.230.230; 16.O.230.231; 16.O.230.236; 16.O.230.237; 16.O.230.238; 16.O.230.239; 16.O.230.154; 16.O.230.157; 16.O.230.166; 16.O.230.169; 16.O.230.172; 16.O.230.175; 16.O.230.240; 16.O.230.244; 16.O.231.228; 16.O.231.229; 16.O.231.230; 16.O.231.231; 16.O.231.236; 16.O.231.237; 16.O.231.238; 16.O.231.239; 16.O.231.154; 16.O.231.157; 16.O.231.166; 16.O.231.169; 16.O.231.172; 16.O.231.175; 16.O.231.240; 16.O.231.244; 16.O.236.228; 16.O.236.229; 16.O.236.230; 16.O.236.231; 16.O.236.236; 16.O.236.237; 16.O.236.238; 16.O.236.239; 16.O.236.154; 16.O.236.157; 16.O.236.166; 16.O.236.169; 16.O.236.172; 16.O.236.175; 16.O.236.240; 16.O.236.244; 16.O.237.228; 16.O.237.229; 16.O.237.23Q; 16.O.237.231; 16.O.237.236; 16.O.237.237; 16.O.237.238; 16.O.237.239; 16.O.237.154; 16.O.237.157; 16.O.237.166; 16.O.237.169; 16.O-237.172; 16.O.237.175; 16.O.237.240; 16.O.237.244; 16.O.238.228; 16.O.238.229; 16.O.238.230; 16.O.238.231; 16.O.238.236; 16.O.238.237; 16.O.238.238; 16.O.238.239; 16.O.238.154; 16.O.238.157; 16.O.238.166; 16.O.238.169; 16.O.238.172; 16.O.238.175; 16.O.238.240; 16.O.238.244; 16.O.239.228; 16.O.239.229; 16.O.239.230; 16.O.239.231; 16.O.239.236; 16.O.239.237; 16.O.239.238; 16.O.239.239; 16.O.239.154; 16.O.239.157; 16.O.239.166; 16.O.239.169; 16.O.239.172; 16.O.239.175; 16.O.239.240; 16.O.239.244; 16.O.154.228; 16.O.154.229; 16.O.154.230; 16.O.154.231; 16.O.154.236; 16.O.154.237; 16.O.154.238; 16.O.154.239; 16.O.154.154; 16.O.154.157; 16.O.154.166; 16.O.154.169; 16.O.154.172; 16.O.154.175; 16.O.154.240; 16.O.154.244; 16.O.157.228; 16.O.157.229; 16.O.157.230; 16.O.157.231; 16.O.157.236; 16.O.157.237; 16.O.157.238; 16.O.157.239; 16.O.157.154; 16.O.157.157; 16.O.157.166; 16.O.157.169; 16.O.157.172; 16.O.157.175; 16.O.157.240; 16.O.157.244; 16.O.166.228; 16.O.166.229; 16.O.166.230; 16.O.166.231; 16.O.166.236; 16.O.166.237; 16.O.166.238; 16.O.166.239; 16.O.166.154; 16.O.166.157; 16.O.166.166; 16.O.166.169; 16.O.166.172; 16.O.166.175; 16.O.166.240; 16.O.166.244; 16.O.169.228; 16.O.169.229; 16.O.169.230; 16.O.169.231; 16.O.169.236; 16.O.169.237; 16.O.169.238; 16.O.169.239; 16.O.169.154; 16.O.169.157; 16.O.169.166; 16.O.169.169; 16.O.169.172; 16.O.169.175; 16.O.169.240; 16.O.169.244; 16.O.172.228; 16.O.172.229; 16.O.172.230; 16.O.172.231; 16.O.172.236; 16.O.172.237; 16.O.172.238; 16.O.172.239; 16.O.172.154; 16.O.172.157; 16.O172.166; 16.O.172.169; 16.O.172.172; 16.O.172.175; 16.O.172.240; 16.O.172.244; 16.O.175.228; 16.O.175.229; 16.O.175.230; 16.O.175.231; 16.O.175.236; 16.O.175.237; 16.O.175.238; 16.O.175.239; 16.O.175.154; 16.O.175.157; 16.O.175.166; 16.O.175.169; 16.O.175.172; 16.O.175.175; 16.O.175.240; 16.O.175.244; 16.O.240.228; 16.O.240.229; 16.O.240.230; 16.O.240.231; 16.O.240.236; 16.O.240.237; 16.O.240.238; 16.O.240.239; 16.O.240.154; 16.O.240.157; 16.O.240.166; 16.O.240.169; 16.O.240.172; 16.O.240.175; 16.O.240.240; 16.O.240.244; 16.O.244.228; 16.O.244.229; 16.O.244.230; 16.O.244.231; 16.O.244.236; 16.O.244.237; 16.O.244.238; 16.O.244.239; 16.O.244.154; 16.O.244.157; 16.O.244.166; 16.O.244.169; 16.O.244.172; 16.O.244.175; 16.O.244.240; 16.O.244.244;

Prodrugs of 16.P

16.P.228.228; 16.P.228.229; 16.P.228.230; 16.P.228.231; 16.P.228.236; 16.P.228.237; 16.P.228.238; 16.P.228.239; 16.P.228.154; 16.P.228.157; 16.P.228.166; 16.P.228.169; 16.P.228.172; 16.P.228.175; 16.P.228.240; 16.P.228.244; 16.P.229.228; 16.P.229.229; 16.P.229.230; 16.P.229.231; 16.P.229.236; 16.P.229.237; 16.P.229.238; 16.P.229.239; 16.P.229.154; 16.P.229.157; 16.P.229.166; 16.P.229.169; 16.P.229.172; 16.P.229.175; 16.P.229.240; 16.P.229.244; 16.P.230.228; 16.P.23Q.229; 16.P.230.230; 16.P.230.231; 16.P.230.236; 16.P.230.237; 16.P.230.238; 16.P.230.239; 16.P.230.154; 16.P.230.157; 16.P.230.166; 16.P.230.169; 16.P.230.172; 16.P.230.175; 16.P.230.240; 16.P.230.244; 16.P.231.228; 16.P.231.229; 16.P.231.230; 16.P.231.231; 16.P.231.236; 16.P.231.237; 16.P.231.238; 16.P.231.239; 16.P.231.154; 16.P.231.157; 16.P.231.166; 16.P.231.169; 16.P.231.172; 16.P.231.175; 16.P.231.240; 16.P.231.244; 16.P.236.228; 16.P.236.229; 16.P.236.230; 16.P.236.231; 16.P.236.236; 16.P.236.237; 16.P.236.238; 16.P.236.239; 16.P.236.154; 16.P.236.157; 16.P.236.166; 16.P.236.169; 16.P.236.172; 16.P.236.175; 16.P.236.240; 16.P.236.244; 16.P.237.228; 16.P.237.229; 16.P.237.230; 16.P.237.231; 16.P.237.236; 16.P.237.237; 16.P.237.238; 16.P.237.239; 16.P.237.154; 16.P.237.157; 16.P.237.166; 16.P.237.169; 16.P.237.172; 16.P.237.175; 16.P.237.240; 16.P.237.244; 16.P.238.228; 16.P.238.229; 16.P.238.230; 16.P.238.231; 16.P.238.236; 16.P.238.237; 16.P.238.238; 16.P.238.239; 16.P.238.154; 16.P.238.157; 16.P.238.166; 16.P.238.169; 16.P.238.172; 16.P.238.175; 16.P.238.240; 16.P.238.244; 16.P.239.228; 16.P.239.229; 16.P.239.230; 16.P.239.231; 16.P.239.236; 16.P.239.237; 16.P.239.238; 16.P.239.239; 16.P.239.154; 16.P.239.157; 16.P.239.166; 16.P.239.169; 16.P.239.172; 16.P.239.175; 16.P.239.240; 16.P.239.244; 16.P.154.228; 16.P.154.229; 16.P.154.230; 16.P.154.231; 16.P.154.236; 16.P.154.237; 16.P.154.238; 16.P.154.239; 16.P.154.154; 16.P.154.157; 16.P.154.166; 16.P.154.169; 16.P.154.172; 16.P.154.175; 16.P.154.240; 16.P.154.244; 16.P.157.228; 16.P.157.229; 16.P.157.230; 16.P.157.231; 16.P.157.236; 16.P.157.237; 16.P.157.238; 16.P.157.239; 16.P.157.154; 16.P.157.157; 16.P.157.166; 16.P.157.169; 16.P.157.172; 16.P.157.175; 16.P.157.240; 16.P.157.244; 16.P.166.228; 16.P.166.229; 16.P.166.230; 16.P.166.231; 16.P.166.236; 16.P.166.237; 16.P.166.238; 16.P.166.239; 16.P.166.154; 16-P166.157; 16.P.166.166; 16.P.166.169; 16.P.166.172; 16.P.166.175; 16.P.166.240; 16.P.166.244; 16.P.169.228; 16.P.169.229; 16.P.169.230; 16.P.169.231; 16.P.169.236; 16.P.169.237; 16.P.169.238; 16.P.169.239; 16.P.169.154; 16.P.169.157; 16.P.169.166; 16.P.169.169; 16.P.169.172; 16.P.169.175; 16.P.169.240; 16.P.169.244; 16.P.172.228; 16.P.172.229; 16.P.172.230; 16.P.172.231; 16.P.172.236; 16.P.172.237; 16.P.172.238; 16.P.172.239; 16.P.172.154; 16.P.172.157; 16..P '.172.166; 16.P.172.169; 16.P.172.172; 16.P.172.175; 16.P.172.240; 16.P.172.244; 16.P.175.228; 16.P.175.229; 16.P.175.230; 16.P.175.231; 16.P.175.236; 16.P.175.237; 16.P.175.238; 16.P.175.239; 16.P.175.154; 16.P.175.157; 16.P.175.166; 16.P.175.169; 16.P.175.172; 16.P.175.175; 16.P.175.240; 16.P.175.244; 16.P.240.228; 16.P.240.229; 16.P.240.230; 16.P.240.231; 16.P.240.236; 16.P.240.237; 16.P.240.238; 16.P.240.239; 16.P.240.154; 16.P.240.157; 16.P.240.166; 16.P.240.169; 16.P.240.172; 16.P.240.175; 16.P.240.240; 16.P.240.244; 16.P.244.228; 16.P.244.229; 16.P.244.230; 16.P.244.231; 16.P.244.236; 16.P.244.237; 16.P.244.238; 16.P.244.239; 16.P.244.154; 16.P.244.157; 16.P.244.166; 16.P.244.169; 16.P.244.172; 16.P.244.175; 16.P.244.240; 16.P.244.244;

Prodrugs of 16.U

16.U.228.228; 16.U.228.229; 16.U.228.230; 16.U.228.231; 16.U.228.236; 16.U.228.237; 16.U.228.238; 16.U.228.239; 16.U.228.154; 16.U.228.157; 16.U.228.166; 16.U.228.169; 16.U.228.172; 16.U.228.175; 16.U.228.240; 16.U.228.244; 16.U.229.228; 16.U.229.229; 16.U.229.230; 16.U.229.231; 16.U.229.236; 16.U.229.237; 16.U.229.238; 16.U.229.239; 16.U.229.154; 16.U.229.157; 16.U.229.166; 16.U.229.169; 16.U.229.172; 16.U.229.175; 16.U.229.240; 16.U.229.244; 16.U.230.228; 16.U.230.229; 16.U.230.230; 16.U.230.231; 16.U.230.236; 16.U.23Q.237; 16.U.230.238; 16.U.230.239; 16.U.230.154; 16.U.23Q.157; 16.U.230.166; 16.U.230.169; 16.U.230.172; 16.U.230.175; 16.U.230.24Q; 16.U.230.244; 16.U.231.228; 16.U.231.229; 16.U.231.230; 16.U.231.231; 16.U.231.236; 16.U.231.237; 16.U.231.238; 16.U.231.239; 16.U.231.154; 16.U.231.157; 16.U.231.166; 16.U.231.169; 16.U.231.172; 16.U.231.175; 16.U.231.240; 16.U.231.244; 16.U.236.228; 16.U.236.229; 16.U.236.230; 16.U.236.231; 16.U.236.236; 16.U.236.237; 16.U.236.238; 16.U.236.239; 16.U.236.154; 16.U.236.157; 16.U.236.166; 16.U.236.169; 16.U.236.172; 16.U.236.175; 16.U.236.240; 16.U.236.244; 16.U.237.228; 16.U.237.229; 16.U.237.230; 16.U.237.231; 16.U.237.236; 16.U.237.237; 16.U.237.238; 16.U.237.239; 16.U.237.154; 16.U.237.157; 16.U.237.166; 16.U.237.169; 16.U.237.172; 16.U.237.175; 16.U.237.240; 16.U.237.244; 16.U.238.228; 16.U.238.229; 16.U.238.230; 16.U.238.231; 16.U.238.236; 16.U.238.237; 16.U.238.238; 16.U.238.239; 16.U.238.154; 16.U.238.157; 16.U.238.166; 16.U.238.169; 16.U.238.172; 16.U.238.175; 16.U.238.240; 16.U.238.244; 16.U.239.228; 16.U.239.229; 16.U.239.230; 16.U.239.231; 16.U.239.236; 16.U.239.237; 16.U.239.238; 16.U.239.239; 16.U.239.154; 16.U.239.157; 16.U.239.166; 16.U.239.169; 16.U.239.172; 16.U.239.175; 16.U.239.240; 16.U.239.244; 16.U.154.228; 16.U.154.229; 16.U.154.230; 16.U.154.231; 16.U.154.236; 16.U.154.237; 16.U.154.238; 16.U.154.239; 16.U.154.154; 16.U.154.157; 16.U.154.166; 16.U.154.169; 16.U.154.172; 16.U.154.175; 16.U.154.240; 16.U.154.244; 16.U.157.228; 16.U.157.229; 16.U.157.230; 16.IJ.157.231; 16.U.157.236; 16.U.157.237; 16.U.157.238; 16.U.157.239; 16.U.157.154; 16.U.157.157; 16.U.157.166; 16.U.157.169; 16.U.157.172; 16.U.157.175; 16.U.157.240; 16.U.157.244; 16.U.166.228; 16.U.166.229; 16.U.166.230; 16.U.166.231; 16.U.166.236; 16.U.166.237; 16.U.166.238; 16.U.166.239; 16.U.166.154; 16.U.166.157; 16.U.166.166; 16.U.166.169; 16.U.166.172; 16.U.166.175; 16.U.166.240; 16.U.166.244; 16.U.169.228; 16.U.169.229; 16.U.169.230; 16.U.169.231; 16.U.169.236; 16.U.169.237; 16.U.169.238; 16.U.169.239; 16.U.169.154; 16.U.169.157; 16.U.169.166; 16.U.169.169; 16.U.169.172; 16.U.169.175; 16.U.169.240; 16.U.169.244; 16.U.172.228; 16.U.172.229; 16.U.172.230; 16.U.172.231; 16.U.172.236; 16.U.172.237; 16.U.172.238; 16.U.172.239; 16.U.172.154; 16.U.172.157; 16.U.172.166; 16.U.172.169; 16.U.172.172; 16.U.172.175; 16.U.172.240; 16.U.172.244; 16.U.175.228; 16.U.175.229; 16.U.175.230; 16.U.175.231; 16.U.175.236; 16.U.175.237; 16.U.175.238; 16.U.175.239; 16.U.175.154; 16.U.175.157; 16.U.175.166; 16.U.175.169; 16.U.175.172; 16.U.175.175; 16.U.175.240; 16.U.175.244; 16.U.240.228; 16.U.240.229; 16.U.240.230; 16.U.240.231; 16.U.240.236; 16.U.240.237; 16.U.240.238; 16.U.240.239; 16.U.240.154; 16.U.240.157; 16.U.240.166; 16.U.240.169; 16.U.240.172; 16.U.240.175; 16.U.240.240; 16.U.240.244; 16.U.244.228; 16.U.244.229; 16.U.244.23Q; 16.U.244.231; 16.U.244.236; 16.U.244.237; 16.U.244.238; 16.U.244.239; 16.U.244.154; 16.U.244.157; 16.U.244.166; 16.U.244.169; 16.U.244.172; 16.U.244.175; 16.U.244.240; 16.U.244.244;

Prodrugs of 16.CD

16.CD.228.228; 16.CD.228.229; 16.CD.228.230; 16.CD.228.231; 16.CD.228.236; 16.CD.228.237; 16.CD.228.238; 16.CD.228.239; 16.CD.228-154; 16.CD.228.157; 16.CD.228.166; 16.CD.228.169; 16.CD.228.172; 16.CD.228.175; 16.CD.228.240; 16.CD.228.244; 16.CD.229.228; 16.CD.229.229; 16.CD.229.230; 16.CD.229.231; 16.CD.229.236; 16.CD.229.237; 16.CD.229.238; 16.CD.229.239; 16.CD.229.154; 16.CD.229.157; 16.CD.229.166; 16. CD.229.169; 16. CD.229.172; 16.CD.229.175; 16.CD.229.240; 16.CD.229.244; 16.CD.230.228; 16.CD.230.229; 16.CD.230.230; 16.CD.230.231; 16.CD.230.236; 16.CD.230.237; 16.CD.230.238; 16.CD.230.239; 16.CD.230.154; 16.CD.230.157; 16.CD.230.166; 16.CD.230.169; 16.CD.230.172; 16.CD.230.175; 16.CD.230.240; 16.CD.230.244; 16.CD.231.228; 16.CD.231.229; 16.CD.231.230; 16.CD.231.231; 16.CD.231.236; 16.CD.231.237; 16.CD.231.238; 16.CD.231.239; 16.CD.231.154; 16.CD.231.157; 16.CD.231.166; 16.CD.231.169; 16.CD.231.172; 16.CD.231.175; 16.CD.231.240; 16.CD.231.244; 16.CD.236.228; 16.CD.236.229; 16.CD.236.230; 16.CD.236.231; 16.CD.236.236; 16.CD.236.237; 16.CD.236.238; 16.CD.236.239; 16.CD.236.154; 16. CD.236.157; 16.CD.236.166; 16.CD.236.169; 16. CD.236.172; 16.CD.236.175; 16.CD.236.240; 16.CD.236.244; 16.CD.237.228; 16.CD.237.229; 16.CD.237.230; 16.CD.237.231; 16.CD.237.236; 16.CD.237.237; 16.CD.237.238; 16.CD.237.239; 16.CD.237.154; 16.CD.237.157; 16.CD.237.166; 16.CD.237.169; 16-CP.237.172; 16.CD.237.175; 16.CD.237.240; 16.CD.237.244; 16.CD.238.228; 16.CD.238.229; 16.CD.238.230; 16.CD.238.231; 16.CD.238.236; 16.CD.238.237; 16.CD.238.238; 16.CD.238.239; 16.CD.238.154; 16.CD.238.157; 16.CD.238.166; 16.CD.238.169; 16.CD.238.172; 16.CD.238.175; 16.CD.238.240; 16.CD.238.244; 16.CD.239.228; 16.CD.239.229; 16.CD.239.230; 16.CD.239.231; 16.CD.239.236; 16.CD.239.237; 16.CD.239.238; 16.CD.239.239; 16.CD.239.154; 16.CD.239.157; 16.CD.239.166; 16.CD.239.169; 16.CD.239.172; 16.CD.239.175; 16.CD.239.240; 16.CD.239.244; 16.CD.154.228; 16.CD.154.229; 16.CD.154.230; 16.CD.154.231; 16.CP.154.236; 16.CD.154.237; 16.CD.154.238; 16.CP.154.239; 16.CD.154.154; 16.CD.154.157; 16.CD.154.166; 16.CD.154.169; 16.CD.154.172; 16.CD.154.175; 16.CD.154.240; 16.CD.154.244; 16.CD.157.228; 16.CD.157.229; 16.CD.157.230; 16.CD.157.231; 16.CD.157.236; 16.CD.157.237; 16.CD.157.238; 16.CD.157.239; 16.CD.157.154; 16.CD.157.157; 16.CD.157.166; 16.CD.157.169; 16.CD.157.172; 16.CD.157.175; 16.CD.157.240; 16.CD.157.244; 16.CD.166.228; 16.CD.166.229; 16.CD.166.230; 16.CD.166.231; 16.CD.166.236; 16.CD.166.237; 16.CD.166.238; 16. CD.166239; 16.CD.166.154; 16.CD.166.157; 16.CD.166.166; 16.CD.166.169; 16.CD.166.172; 16.CD.166.175; 16.CD.166.240; 16.CD.166.244; 16.CD.169.228; 16.CD.169.229; 16.CD.169.230; 16.CD.169.231; 16.CD.169.236; 16.CD.169.237; 16.CD.169.238; 16.CD.169.239; 16.CD.169.154; 16.CD.169.157; 16.CD.169.166; 16.CD.169.169; 16. CD.169.172; 16.CD.169.175; 16.CD.169.240; 16.CD.169.244; 16.CD.172.228; 16.CD.172.229; 16.CD.172.230; 16.CD.172.231; 16.CD.172.236; 16.CD.172.237; 16.CD.172.238; 16.CD.172.239; 16.CD.172.154; 16.CD.172.157; 16. CD.172.166; 16.CD.172.169; 16.CD.172.172; 16.CD.172.175; 16.CD.172.240; 16.CD.172.244; 16.CD.175.228; 16.CD.175.229; 16.CD.175.230; 16.CD.175.231; 16.CD.175.236; 16.CD.175.237; 16.CD.175.238; 16.CD.175.239; 16.CP.175.154; 16.CP.175.157; 16.CP.175.166; 16.CD.175.169; 16.CD.175.172; 16.CD.175.175; 16.CD.175.240; 16.CD.175.244; 16.CD.240.228; 16.CD.240.229; 16.CD.240.230; 16.CD.240.231; 16.CD.240.236; 16.CD.240.237; 16.CD.240.238; 16.CP.24Q.239; 16.CD.240.154; 16.CP.240.157; 16.CD.240.166; 16.CD.240.169; 16.CD.240.172; 16.CD.240.175; 16.CP.240.240; 16.CP.240.244; 16.CP.244.228; 16.CP.244.229; 16.CP.244.230; 16.CP.244.231; 16.CP.244.236; 16.CP.244.237; 16.CP.244.238; 16.CP.244.239; 16.CP.244.154; 16.CP.244.157; 16.CP.244.166; 16.CP.244.169; 16.CP.244.172; 16.CP.244.175; 16.CP.244.240; 16.CP.244.244;

Prodrugs of 16.EB

16.EB.228.228; 16.EB.228.229; 16.EB.228.230; 16.EB.228.231; 16.EB.228.236; 16.EB.228.237; 16.EB.228.238; 16.EB.228.239; 16.EB.228.154; 16.EB.228.157; 16.EB .228.166; 16.EB.228.169; 16.EB.228.172; 16.EB.228.175; 16.EB.228.240; 16.EB.228.244; 16.EB.229.228; 16.EB.229.229; 16.EB.229.230; 16.EB.229.231; 16.EB.229.236; 16.EB .229.237; 16.EB.229.238; 16.EB.229.239; 16.EB.229.154; 16.EB.229.157; 16.EB.229.166; 16.EB.229.169; 16.EB.229.172; 16.EB.229.175; 16.EB.229.240; 16.EB.229.244; 16.EB.230.228; 16.EB.230.229; 16.EB.230.230; 16.EB.230.231; 16.EB.230.236; 16.EB.230.237; 16.EB.230.238; 16.EB.230.239; 16.EB.230.154; 16.EB.230.157; 16.EB.230.166; 16.EB.230.169; 16.EB.230.172; 16.EB.230.175; 16.EB.230.240; 16.EB.230.244; 16.EB.231.228; 16.EB .231.229; 16.EB.231.230; 16.EB.231.231; 16.EB.231.236; 16.EB.231.237; 16.EB.231.238; 16.EB.231.239; 16.EB.231.154; 16.EB.231.157; 16.EB.231.166; 16.EB.231.169; 16.EB.231.172; 16.EB.231.175; 16.EB.231.240; 16.EB .231.244; 16.EB.236.228; 16.EB.236.229; 16.EB.236.230; 16.EB.236.231; 16.EB.236.236; 16.EB.236.237; 16.EB.236.238; 16.EB.236.239; 16.EB.236.154; 16.EB.236.157; 16.EB.236.166; 16.EB.236.169; 16.EB.236.172; 16.EB.236.175; 16.EB.236.240; 16.EB.236.244; 16.EB.237.228; 16.EB.237.229; 16.EB.237.230; 16.EB.237.231; 16.EB.237.236; 16.EB.237.237; 16.EB.237.238; 16.EB.237.239; 16.EB.237.154; 16.EB.237.157; 16.EB.237.166; 16.EB.237.169; 16.EB.237.172; 16.EB.237.175; 16.EB.237.240; 16.EB.237.244; 16.EB.238.228; 16.EB.238.229; 16.EB.238.230; 16.EB.238.231; 16.EB.238.236; 16.EB.238.237; 16.EB.238.238; 16.EB.238.239; 16.EB.238.154; 16.EB.238.157; 16.EB.238.166; 16.EB.238.169; 16.EB.238.172; 16.EB.238.175; 16.EB.238.240; 16.EB.238.244; 16.EB.239.228; 16.EB.239.229; 16.EB.239.230; 16.EB.239.231; 16.EB.239.236; 16.EB.239.237; 16.EB.239.238; 16.EB.239.239; 16.EB.239.154; 16.EB.239.157; 16.EB.239.166; 16.EB.239.169; 16.EB.239.172; 16.EB.239.175; 16.EB.239.240; 16.EB.239.244; 16.EB.154.228; 16.EB.154.229; 16.EB.154.230; 16.EB.154.231; 16.EB.154.236; 16.EB.154.237; 16.EB.154.238; 16.EB.154.239; 16.EB.154.154; 16.EB.154.157; 16.EB.154.166; 16.EB.154.169; 16.EB.154.172; 16.EB.154.175; 16.EB.154.240; 16.EB.154.244; 16.EB.157.228; 16.EB.157.229; 16.EB.157.230; 16.EB.157.231; 16.EB.157.236; 16.EB.157.237; 16.EB.157.238; 16.EB.157.239; 16.EB.157.154; 16.EB.157.157; 16.EB.157.166; 16.EB.157.169; 16.EB.157.172; 16.EB.157.175; 16.EB.157.240; 16.EB.157.244; 16.EB.166.228; 16.EB.166.229; 16.EB.166.230; 16.EB.166.231; 16.EB.166.236; 16.EB.166.237; 16.EB.166.238; 16.EB.166.239; 16.EB.166.154; 16.EB.166.157; 16.EB.166.166; 16.EB.166.169; 16.EB.166.172; 16.EB.166.175; 16.EB.166.240; 16.EB.166.244; 16.EB.169.228; 16.EB.169.229; 16.EB.169.230; 16.EB.169.231; 16.EB.169.236; 16.EB.169.237; 16.EB.169.238; 16.EB.169.239; 16.EB.169.154; 16.EB.169.157; 16.EB.169.166; 16.EB.169.169; 16.EB.169.172; 16.EB.169.175; 16.EB.169.240; 16.EB.169.244; 16.EB.172.228; 16.EB.172.229; 16.EB.172.230; 16.EB.172.231; 16.EB.172.236; 16.EB.172.237; 16.EB.172.238; 16.EB.172.239; 16.EB.172.154; 16.EB.172.157; 16.EB.172.166; 16.EB.172.169; 16.EB.172.172; 16.EB.172.175; 16.EB.172.240; 16.EB.172.244; 16.EB.175.228; 16.EB.175.229; 16.EB.175.230; 16.EB.175.231; 16.EB.175.236; 16.EB.175.237; 16.EB.175.238; 16.EB.175.239; 16.EB.175.154; 16.EB.175.157; 16.EB.175.166; 16.EB.175.169; 16.EB.175.172; 16.EB.175.175; 16.EB.175.240; 16.EB.175.244; 16.EB.240.228; 16.EB.240.229; 16.EB.240.230; 16.EB.240.231; 16.EB.240.236; 16.EB.240.237; 16.EB.240.238; 16.EB.240.239; 16.EB.240.154; 16.EB.240.157; 16.EB.240.166; 16.EB.240.169; 16.EB.240.172; 16.EB.240.175; 16.EB.240.240; 16.EB.240.244; 16.EB.244.228; 16.EB.244.229; 16.EB.244.230; 16.EB.244.231; 16.EB.244.236; 16.EB .244.237; 16.EB.244.238; 16.EB .244.239; 16.EB.244.154; 16.EB.244.157; 16.EB.244.166; 16.EB.244.169; 16.EB.244.172; 16.EB.244.175; 16.EB.244.240; 16.EB.244.244;

Prodrugs of 17.B

17.B.228.228; 17.B.228.229; 17.B.228.230; 17.B.228.231; 17.B.228.236; 17.B.228.237; 17.B.228.238; 17.B.228.239; 17.B.228.154; 17.B.228.157; 17.B.228.166; 17.B.228.169; 17.B.228.172; 17.B.228.175; 17.B.228.240; 17.B.228.244; 17.B.229.228; 17.B.229.229; 17.B.229.230; 17.B.229.231; 17.B.229.236; 17.B.229.237; 17.B.229.238; 17.B.229.239; 17.B.229.154; 17.B.229.157; 17.B.229.166; 17.B.229.169; 17.B.229.172; 17.B.229.175; 17.B.229.240; 17.B.229.244; 17.B.23Q.228; 17.B.230.229; 17.B.230.230; 17.B.230.231; 17.B.230.236; 17.B.230.237; 17.B.230.238; 17.B.230.239; 17.B.230.154; 17.B.230.157; 17.B.230.166; 17.B.230.169; 17.B.230.172; 17.B.230.175; 17.B.230.240; 17.B.230.244; 17.B.231.228; 17.B.231.229; 17.B.231.230; 17.B.231.231; 17.B.231.236; 17.B.231.237; 17.B.231.238; 17.B.231.239; 17.B.231.154; 17.B.231.157; 17.B.231.166; 17.B.231.169; 17.B.231.172; 17.B.231.175; 17.B.231.240; 17.B.231.244; 17.B.236.228; 17.B.236.229; 17.B.236.230; 17.B.236.231; 17.B.236.236; 17.B.236.237; 17.B.236.238; 17.B.236.239; 17.B.236.154; 17.B.236.157; 17.B.236.166; 17.B.236.169; 17.B.236.172; 17.B.236.175; 17.B.236.240; 17.B.236.244; 17.B.237.228; 17.B.237.229; 17.B.237.23Q; 17.B.237.231; 17.B.237.236; 17.B.237.237; 17.B.237.238; 17.B.237.239; 17.B.237.154; 17.B.237.157; 17.B.237.166; 17.B.237.169; 17.B.237.172; 17.B.237.175; 17.B.237.240; 17.B.237.244; 17.B.238.228; 17.B.238.229; 17.B.238.230; 17.B.238.231; 17.B.238.236; 17.B.238.237; 17.B.238.238; 17.B.238.239; 17.B.238.154; 17.B.238.157; 17.B.238.166; 17.B.238.169; 17.B.238.172; 17.B.238.175; 17.B.238.24Q; 17.B.238.244; 17.B.239.228; 17.B.239.229; 17.B.239.230; 17.B.239.231; 17.B.239.236; 17.B.239.237; 17.B.239.238; 17.B.239.239; 17.B.239.154; 17.B.239.157; 17.B.239.166; 17.B.239.169; 17.B.239.172; 17.B.239.175; 17.B.239.240; 17.B.239.244; 17.B.154.228; 17.B.154.229; 17.B.154.230; 17.B.154.231; 17.B.154.236; 17.B.154.237; 17.B.154.238; 17.B.154.239; 17.B.154.154; 17.B.154.157; 17.B.154.166; 17.B.154.169; 17.B.154.172; 17.B.154.175; 17.B.154.240; 17.B.154.244; 17.B.157.228; 17.B.157.229; 17.B.157.230; 17.B.157.231; 17.B.157.236; 17.B.157.237; 17.B.157.238; 17.B.157.239; 17.B.157.154; 17.B.157.157; 17.B.157.166; 17.B.157.169; 17.B.157.172; 17.B.157.175; 17.B.157.240; 17.B.157.244; 17.B.166.228; 17.B.166.229; 17.B.166.230; 17.B.166.231; 17.B.166.236; 17.B.166.237; 17.B.166.238; 17.B.166.239; 17.B.166.154; 17.B.166.157; 17.B.166.166; 17.B.166.169; 17.B.166.172; 17.B.166.175; 17.B.166.240; 17.B.166.244; 17.B.169.228; 17.B.169.229; 17.B.169.230; 17.B.169.231; 17.B.169.236; 17.B.169.237; 17.B.169.238; 17.B.169.239; 17.B.169.154; 17.B.169.157; 17.B.169.166; 17.B.169.169; 17.B.169.172; 17.B.169.175; 17.B.169.240; 17.B.169.244; 17.B.172.228; 17.B.172.229; 17.B.172.230; 17.B.172.231; 17.B.172.236; 17.B.172.237; 17.B.172.238; 17.B.172.239; 17.B.172.154; 17.B.172.157; 17.B.172.166; 17.B.172.169; 17.B.172.172; 17.B.172.175; 17.B.172.240; 17.B.172.244; 17.B.175.228; 17.B.175.229; 17.B.175.230; 17.B.175.231; 17.B.175.236; 17.B.175.237; 17.B.175.238; 17.B.175.239; 17.B.175.154; 17.B.175.157; 17.B.175.166; 17.B.175.169; 17.B.175.172; 17.B.175.175; 17.B.175.240; 17.B.175.244; 17.B.240.228; 17.B.240.229; 17.B.240.230; 17.B.240.231; 17.B.240.236; 17.B.240.237; 17.B.240.238; 17.B.240.239; 17.B.240.154; 17.B.240.157; 17.B.240.166; 17.B.240.169; 17.B.240.172; 17.B.240.175; 17.B.240.240; 17.B.240.244; 17.B.244.228; 17.B.244.229; 17.B.244.230; 17.B.244.231; 17.B.244.236; 17.B.244.237; 17.B.244.238; 17.B.244.239; 17.B.244.154; 17.B.244.157; 17.B.244.166; 17.B.244.169; 17.B.244.172; 17.B.244.175; 17.B.244.240; 17.B.244.244;

Prodrugs of 17.D

17.D.228.228; 17.D.228.229; 17.D.228.230; 17.D.228.231; 17.D.228.236; 17.D.228.237; 17.D.228.238; 17.D.228.239; 17.D.228.154; 17.D.228.157; 17.D.228.166; 17.D.228.169; 17.D.228.172; 17.D.228.175; 17.D.228.240; 17.D.228.244; 17.D.229.228; 17.D.229.229; 17.D.229.230; 17.D.229.231; 17.D.229.236; 17.D.229.237; 17.D.229.238; 17.D.229.239; 17.D.229.154; 17.D.229.157; 17.D.229.166; 17.D.229.169; 17.D.229.172; 17.D.229.175; 17.D.229.240; 17.D.229.244; 17.D.23Q.228; 17.D.230.229; 17.D.230.230; 17.D.230.231; 17.D.230.236; 17.D.230.237; 17.D.230.238; 17.D.230.239; 17.D.230.154; 17.D.230.157; 17.D.230.166; 17.D.23Q.169; 17.D.230.172; 17.D.230.175; 17.D.230.240; 17.D.230.244; 17.D.231.228; 17.D.231.229; 17.D.231.230; 17.D.231.231; 17.D.231.236; 17.D.231.237; 17.D.231.238; 17.D.231.239; 17.D.231.154; 17.D.231.157; 17.D.231.166; 17.D.231.169; 17.D.231.172; 17.D.231.175; 17.D.231.240; 17.D.231.244; 17.D.236.228; 17.D.236.229; 17.D.236.230; 17.D.236.231; 17.D.236.236; 17.D.236.237; 17.D.236.238; 17.D.236.239; 17.D.236.154; 17.D.236.157; 17.D.236.166; 17.D.236.169; 17.D.236.172; 17.D.236.175; 17.D.236.240; 17.D.236.244; 17.D.237.228; 17.D.237.229; 17.D.237.230; 17.D.237.231; 17.D.237.236; 17.D.237.237; 17.D.237.238; 17.D.237.239; 17.D.237.154; 17.D.237.157; 17.D.237.166; 17.D.237.169; 17.D.237.172; 17.D.237.175; 17. ,D.237. ,240; 17.D.237.244; 17.D.238.228; 17.D.238.229; 17.D.238.230; 17.D.238.231; 17.D.238.236; 17.D.238.237; 17.D.238.238; 17.D.238.239; 17.D.238.154; 17.D.238.157; 17.D.238.166; 17.D.238.169; 17.D.238.172; 17.D.238.175; 17.D.238.240; 17.D.238.244; 17.D.239.228; 17.D.239.229; 17.D.239.230; 17.D.239.231; 17.D.239.236; 17.D.239.237; 17.D.239.238; 17.D.239.239; 17.D.239.154; 17.D.239.157; 17.D.239.166; 17.D.239.169; 17.D.239.172; 17.D.239.175; 17.D.239.240; 17.D.239.244; 17.D.154.228; 17.D.154.229; 17.D.154.230; 17.D.154.231; 17.D.154.236; 17.D.154.237; 17.D.154.238; 17.D.154.239; 17.D.154154; 17.D.154.157; 17.D.154.166; 17.D.154.169; 17.D.154.172; 17.D.154.175; 17.D.154.240; 17.D.154.244; 17.D.157.228; 17.D.157.229; 17.D.157.230; 17.D.157.231; 17.D.157.236; 17.D.157.237; 17.D.157.238; 17.D.157.239; 17.D.157.154; 17.D.157.157; 17.D.157.166; 17.D.157.169; 17.D.157.172; 17.D.157.175; 17.D.157.240; 17.D.157.244; 17.D.166.228; 17.D.166.229; 17.D.166.230; 17.D.166.231; 17.D.166.236; 17.D.166.237; 17.D.166.238; 17.D.166.239; 17.D.166.154; 17.D.166.157; 17.D.166.166; 17.D.166.169; 17.D.166.172; 17.D.166.175; 17.D.166.240; 17.D.166.244; 17.D.169.228; 17.D.169.229; 17.D.169.230; 17.D.169.231; 17.D.169.236; 17.D.169.237; 17.D.169.238; 17.D.169.239; 17.D.169.154; 17.D.169.157; 17.D.169.166; 17.D.169.169; 17.D.169.172; 17.D.169.175; 17.D.169.240; 17.D.169.244; 17.D.172.228; 17.D.172.229; 17.D.172.230; 17.D.172.231; 17.D.172.236; 17.D.172.237; 17.D.172.238; 17.D.172.239; 17.D.172.154; 17.D.172.157; 17.D.172.166; 17.D.172.169; 17.D.172.172; 17.D.172.175; 17.D.172.240; 17.D.172.244; 17.D.175.228; 17.D.175.229; 17.D.175.230; 17.D.175.231; 17.D.175.236; 17.D.175.237; 17.D.175.238; 17.D.175.239; 17.D.175.154; 17.D.175.157; 17.D.175.166; 17.D.175.169; 17.D.175.172; 17.D.175.175; 17.D.175.240; 17.D.175.244; 17.D.240.228; 17.D.240.229; 17.D.240.230; 17.D.240.231; 17.D.240.236; 17.D.240.237; 17.D.240.238; 17.D.240.239; 17.D.240.154; 17.D.240.157; 17.D.240.166; 17.D.240.169; 17.D.240.172; 17.D.240.175; 17.D.240.240; 17.D.240.244; 17.D.244.228; 17.D.244.229; 17.D.244.230; 17.D.244.231; 17.D.244.236; 17.D.244.237; 17.D.244.238; 17.D.244.239; 17.D.244.154; 17.D.244.157; 17.D.244.166; 17.D.244.169; 17.D.244.172; 17.D.244.175; 17.D.244.240; 17.D.244.244;

Prodrugs of 17.AB

17.AB.228.228; 17.AB.228.229; 17. AB .228.230; 17.AB.228.231; 17.AB.228.236; 17.AB.228.237; 17.AB.228.238; 17.AB.228.239; 17.AB.228.154; 17.AB.228.157; 17.AB.228.166; 17.AB.228.169; 17.AB.228.172; 17.AB.228.175; 17.AB.228.240; 17.AB.228.244; 17.AB.229.228; 17.AB.229.229; 17. AB.229.230; 17.AB.229.231; 17.AB.229.236; 17.AB.229.237; 17.AB.229.238; 17.AB.229.239; 17.AB.229.154; 17.AB.229.157; 17.AB.229.166; 17.AB.229.169; 17. AB.229.172; 17.AB.229.175; 17.AB.229.240; 17. AB.229.244; 17.AB.230.228; 17.AB.230.229; 17. AB.230.230; 17.AB.230.231; 17.AB.230.236; 17.AB.230.237; 17.AB.230.238; 17.AB.230.239; 17.AB.230.154; 17.AB.230.157; 17.AB.230.166; 17.AB.230.169; 17.AB.230.172; 17.AB.230.175; 17.AB.230.240; 17.AB.230.244; 17.AB.231.228; 17. AB.231.229; 17.AB.231.230; 17.AB.231.231; 17.AB.231.236; 17.AB.231.237; 17.AB.231.238; 17.AB.231.239; 17.AB.231.154; 17.AB.231.157; 17.AB.231.166; 17.AB.231.169; 17.AB.231.172; 17.AB.231.175; 17.AB.231.240; 17.AB.231.244; 17.AB.236.228; 17.AB.236.229; 17.AB.236.230; 17.AB.236.231; 17.AB.236.236; 17.AB.236.237; 17.AB.236.238; 17.AB.236.239; 17.AB.236.154; 17.AB.236.157; 17.AB.236.166; 17.AB.236.169; 17.AB.236.172; 17. AB .236.175; 17.AB.236.240; 17.AB.236.244; 17.AB.237.228; 17.AB.237.229; 17.AB.237.230; 17.AB.237.231; 17.AB.237.236; 17.AB.237.237; 17.AB.237.238; 17.AB.237.239; 17.AB.237.154; 17. AB.237.157; 17.AB.237.166; 17.AB.237.169; 17.AB.237.172; 17.AB.237.175; 17.AB.237.240; 17.AB.237.244; 17.AB.238.228; 17.AB.238.229; 17.AB.238.230; 17.AB.238.231; 17.AB.238.236; 17.AB.238.237; 17.AB.238.238; 17.AB.238.239; 17.AB.238.154; 17.AB.238.157; 17.AB.238.166; 17. AB .238.169; 17.AB.238.172; 17.AB.238.175; 17.AB.238.240; 17.AB.238.244; 17.AB.239.228; 17.AB.239.229; 17.AB.239.230; 17.AB.239.231; 17.AB.239.236; 17.AB.239.237; 17.AB.239.238; 17.AB.239.239; 17.AB.239.154; 17.AB.239.157; 17.AB.239.166; 17.AB.239.169; 17.AB.239.172; 17.AB.239.175; 17.AB.239.240; 17.AB.239.244; 17.AB.154.228; 17.AB.154.229; 17.AB.154.230; 17.AB.154.231; 17.AB.154.236; 17.AB.154.237; 17.AB.154.238; 17.AB.154.239; 17.AB.154.154; 17.AB.154.157; 17.AB.154.166; 17.AB.154.169; 17.AB.154.172; 17.AB.154.175; 17.AB.154.240; 17.AB.154.244; 17.AB.157.228; 17.AB.157.229; 17.AB.157.230; 17.AB.157.231; 17.AB.157.236; 17.AB.157.237; 17.AB.157.238; 17.AB.157.239; 17.AB.157.154; 17.AB.157.157; 17.AB.157.166; 17.AB.157.169; 17.AB.157.172; 17.AB.157.175; 17.AB.157.240; 17.AB.157.244; 17.AB.166.228; 17.AB.166.229; 17.AB.166.230; 17.AB.166.231; 17.AB.166.236; 17.AB.166.237; 17.AB.166.238; 17.AB.166.239; 17.AB.166.154; 17.AB.166.157; 17.AB.166.166; 17.AB.166.169; 17.AB.166.172; 17.AB.166.175; 17.AB.166.240; 17.AB.166.244; 17.AB.169.228; 17.AB.169.229; 17.AB.169.230; 17.AB.169.231; 17.AB.169.236; 17.AB.169.237; 17.AB.169.238; 17.AB.169.239; 17.AB.169.154; 17.AB.169.157; 17.AB.169.166; 17.AB.169.169; 17.AB.169.172; 17.AB.169.175; 17.AB.169.240; 17. AB.169.244; 17.AB.172.228; 17.AB.172.229; 17.AB.172.230; 17.AB.172.231; 17. AB.172.236; 17.AB.172.237; 17.AB.172.238; 17.AB.172.239; 17.AB.172.154; 17.AB.172.157; 17.AB.172.166; 17.AB.172.169; 17.AB.172.172; 17.AB.172.175; 17.AB.172.240; 17.AB.172.244; 17. AB.175.228; 17. AB.175.229; 17.AB.175.230; 17.AB.175.231; 17. AB.175.236; 17.AB.175.237; 17.AB.175.238; 17.AB.175.239; 17.AB.175.154; 17.AB.175.157; 17.AB.175.166; 17.AB.175.169; 17.AB.175.172; 17.AB.175.175; 17.AB.175.240; 17. AB.175.244; 17.AB.240.228; 17.AB.240.229; 17.AB.240.230; 17.AB.240.231; 17.AB.240.236; 17.AB.240.237; 17.AB.240.238; 17. AB.240.239; 17.AB.24Q.154; 17.AB.240.157; 17.AB.240.166; 17.AB.240.169; 17.AB.240.172; 17.AB.240.175; 17.AB.240.240; 17.AB.240.244; 17.AB.244.228; 17.AB.244.229; 17.AB.244.230; 17.AB.244.231; 17.AB.244.236; 17.AB.244.237; 17.AB.244.238; 17.AB.244.239; 17.AB.244.154; 17.AB.244.157; 17.AB.244.166; 17.AB.244.169; 17.AB.244.172; 17.AB.244.175; 17.AB.244.240; 17.AB.244.244;

Prodrugs of 17.BI

17.BI.228.228; 17.BI.228.229; 17.BI.228.230; 17.BI.228.231; 17.BI.228.236; 17.BI.228.237; 17.BI.228.238; 17.BI.228.239; 17.BI.228.154; 17.BI.228.157; 17.BI.228.166; 17.BI.228.169; 17.BI.228.172; 17.BI.228.175; 17.BI.228.240; 17.BI.228.244; 17.BI.229.228; 17.BI.229.229; 17.BI.229.230; 17.BI.229.231; 17.BI.229.236; 17.BI.229.237; 17.BL229.238; 17.BI.229.239; 17.BI.229.154; 17.BI.229.157; 17.BL229.166; 17.BI.229.169; 17.BI.229.172; 17.BI.229.175; 17.BI.229.240; 17.BI.229.244; 17.BI.230.228; 17.BI.230.229; 17.BI.230.230; 17.BI.230.231; 17.BI.230.236; 17.BI.230.237; 17.BI.23Q.238; 17.BI.230.239; 17.BI.230.154; 17.BI.230.157; 17.BI.230.166; 17.BI.230.169; 17.BI.230.172; 17.BI.230.175; 17.BI.230.240; 17.BI.230.244; 17.BI.231.228; 17.BI.231.229; 17.BI.231.230; 17.BI.231.231; 17.BI.231.236; 17.BI.231.237; 17.BI.231.238; 17.BI.231.239; 17.BI.231.154; 17.BI.231.157; 17.BI.231.166; 17.BI.231.169; 17.BI.231.172; 17.BI.231.175; 17.BI.231.240; 17.BI.231.244; 17.BI.236.228; 17.BI.236.229; 17.BI.236.230; 17.BI.236.231; 17.BI.236.236; 17.BI.236.237; 17.BI.236.238; 17.BI.236.239; 17.BI.236.154; 17.BI.236.157; 17.BI.236.166; 17.BI.236.169; 17.BI.236.172; 17.BI.236.175; 17.BI.236.240; 17.BI.236.244; 17.BI.237.228; 17.BI.237.229; 17.BI.237.230; 17.BI.237.231; 17.BI.237.236; 17.BI.237.237; 17.BI.237.238; 17.BI.237.239; 17.BI.237.154; 17.BI.237.157; 17.BI.237.166; 17.BI.237.169; 17.BI.237.172; 17.BI.237.175; 17.BI.237.240; 17.BI.237.244; 17.BI.238.228; 17.BI.238.229; 17.BI.238.230; 17.BI.238.231; 17.BI.238.236; 17.BI.238.237; 17.BI.238.238; 17.BI.238.239; 17.BI.238.154; 17.BI.238.157; 17.BI.238.166; 17.BI.238.169; 17.BI.238.172; 17.BI.238.175; 17.BI.238.240; 17.BI.238.244; 17.BI.239.228; 17.BI.239.229; 17.BI.239.230; 17.BI.239.231; 17.BI.239.236; 17.BI.239.237; 17.BI.239.238; 17.BI.239.239; 17.BL239.154; 17.BI.239.157; 17.BI.239.166; 17.BI.239.169; 17.BI.239.172; 17.BI.239.175; 17.BI.239.240; 17.BI.239.244; 17.BI.154.228; 17.BI.154.229; 17.BI.154.230; 17.BI.154.231; 17.BI.154.236; 17.BI.154.237; 17.BI.154.238; 17.BI.154.239; 17.BL154.154; 17.BI.154.157; 17.BI.154.166; 17.BI.154.169; 17.BI.154.172; 17.BI.154.175; 17.BI.154.240; 17.BI.154.244; 17.BI.157.228; 17.BI.157.229; 17.BI.157.230; 17.BI.157.231; 17.BI.157.236; 17.BI.157.237; 17.BI.157.238; 17.BI.157.239; 17.BI.157.154; 17.BI.157.157; 17.BI.157.166; 17.BI.157.169; 17.BI.157.172; 17.BI.157.175; 17.BI.157.240; 17.BI.157.244; 17.BI.166.228; 17.BI.166.229; 17.BI.166.230; 17.BI.166.231; 17.BI.166.236; 17.BI.166.237; 17.BI.166.238; 17.BI.166.239; 17.BI.166.154; 17.BI.166.157; 17.BI.166.166; 17.BI.166.169; 17.BI.166.172; 17.BI.166.175; 17.BI.166.240; 17.BI.166.244; 17.BL169.228; 17.BI.169.229; 17.BI.169.230; 17.BI.169.231; 17.BI.169.236; 17.BI.169.237; 17.BI.169.238; 17.BI.169.239; 17.BI.169.154; 17.BI.169.157; 17.BI.169.166; 17.BI.169.169; 17.BI.169.172; 17.BI.169.175; 17.BI.169.240; 17.BI.169.244; 17.BI.172.228; 17.BI.172.229; 17.BI.172.230; 17.BI.172.231; 17.BI.172.236; 17.BI.172.237; 17.BI.172.238; 17.BI.172.239; 17.BI.172.154; 17.BI.172.157; 17.BI.172.166; 17.BI.172.169; 17.BI.172.172; 17.BI.172.175; 17.BI.172.240; 17.BI.172.244; 17.BI.175.228; 17.BI.175.229; 17.BI.175.230; 17.BI.175.231; 17.BI.175.236; 17.BI.175.237; 17.BI.175.238; 17.BI.175.239; 17.BI.175.154; 17.BI.175.157; 17.BI.175.166; 17.BI.175.169; 17.BI.175.172; 17.BI.175.175; 17.BI.175.240; 17.BI.175.244; 17.BI.240.228; 17.BI.240.229; 17.BI.240.230; 17.BI.24Q.231; 17.BI.240.236; 17.BI.240.237; 17.BI.240.238; 17.BI.240.239; 17.BI.240.154; 17.BI.240.157; 17.BI.240.166; 17.BI.240.169; 17.BI.240.172; 17.BI.240.175; 17.BI.24Q.240; 17.BI.240.244; 17.BI.244.228; 17.BI.244.229; 17.BI.244.23Q; 17.BI.244.231; 17.BI.244.236; 17.BI.244.237; 17.BI.244.238; 17.BI.244.239; 17.BI.244.154; 17.BI.244.157; 17.BI.244.166; 17.BI.244.169; 17.BI.244.172; 17.BI.244.175; 17.BI.244.240; 17.BI.244.244;

Prodrugs of 17.1

17.1.228.228; 17.1.228.229; 17.1.228.230; 17.1.228.231; 17.1.228.236; 17.1.228.237; 17.1.228.238; 17.1.228.239; 17.1.228.154; 17.1.228.157; 17.1.228.166; 17.1.228.169; 17.1.228.172; 17.1.228.175; 17.1.228.240; 17.1.228.244; 17.1.229.228; 17.1.229.229; 17.1.229.230; 17.1.229.231; 17.1.229.236; 17.1.229.237; 17.1.229.238; 17.1.229.239; 17.1.229.154; 17.1.229.157; 17.1.229.166; 17.1.229.169; 17.1.229.172; 17.1.229.175; 17.1.229.240; 17.1.229.244; 17.1.230.228; 17.1.230.229; 17.1.230.230; 17.1.230.231; 17.1.230.236; 17.1.230.237; 17.1.230.238; 17.1.230.239; 17.1.230.154; 17.1.230.157; 17.1.230.166; 17.1.230.169; 17.1.230.172; 17.1.230.175; 17.1.230.240; 17.1.230.244; 17.1.231.228; 17.1.231.229; 17.1.231.230; 17.1.231.231; 17.1.231.236; 17.1.231.237; 17.1.231.238; 17.1.231.239; 17.1.231.154; 17.1.231.157; 17.1.231.166; 17.1.231.169; 17.1.231.172; 17.1.231.175; 17.1.231.240; 17.1.231.244; 17.1.236.228; 17.1.236.229; 17.1.236.230; 17.1.236.231; 17.1.236.236; 17.1.236.237; 17.1.236.238; 17.1.236.239; 17.1.236.154; 17.1.236.157; 17.1.236.166; 17.1.236.169; 17.1.236.172; 17.1.236.175; 17.1.236.240; 17.1.236.244; 17.1.237.228; 17.1.237.229; 17.1.237.230; 17.1.237.231; 17.1.237.236; 17.1.237.237; 17.1.237.238; 17.1.237.239; 17.1.237.154; 17.1.237.157; 17.1.237.166; 17.1.237.169; 17.1.237.172; 17.1.237.175; 17.1.237.240; 17.1.237.244; 17.1.238.228; 17.1.238.229; 17.1.238.230; 17.1.238.231; 17.1.238.236; 17.1.238.237; 17.1.238.238; 17.1.238.239; 17.1.238.154; 17.1.238.157; 17.1.238.166; 17.1.238.169; 17.1.238.172; 17.1.238.175; 17.1.238.240; 17.1.238.244; 17.1.239.228; 17.1.239.229; 17.1.239.230; 17.1.239.231; 17.1.239.236; 17.1.239.237; 17.1.239.238; 17.1.239.239; 17.1.239.154; 17.1.239.157; 17.1.239.166; 17.1.239.169; 17.1.239.172; 17.1.239.175; 17.1.239.240; 17.1.239.244; 17.1.154.228; 17.1.154.229; 17.1.154.230; 17.1.154.231; 17.1.154.236; 17.1.154.237; 17.1.154.238; 17.1.154.239; 17.1.154.154; 17.1.154.157; 17.1.154.166; 17.1.154.169; 17.1.154.172; 17.1.154.175; 17.1.154.240; 17.1.154.244; 17.1.157.228; 17.1.157.229; 17.1.157.230; 17.1.157.231; 17.1.157.236; 17.1.157.237; 17.1.157.238; 17.1.157.239; 17.1.157.154; 17.1.157.157; 17.1.157.166; 17.1.157.169; 17.1.157.172; 17.1.157.175; 17.1.157.240; 17.1.157.244; 17.1.166.228; 17.1.166.229; 17.1.166.230; 17.1.166.231; 17.1.166.236; 17.1.166.237; 17.1.166.238; 17.1.166.239; 17.1.166.154; 17.1.166.157; 17.1.166.166; 17.1.166.169; 17.1.166.172; 17.1.166.175; 17.1.166.240; 17.1.166.244; 17.1.169.228; 17.1.169.229; 17.1.169.230; 17.1.169.231; 17.1.169.236; 17.1.169.237; 17.1.169.238; 17.1.169.239; 17.1.169.154; 17.1.169.157; 17.1.169.166; 17.1.169.169; 17.1.169.172; 17.1.169.175; 17.1.169.240; 17.1.169.244; 17.1.172.228; 17.1.172.229; 17.1.172.230; 17.1.172.231; 17.1.172.236; 17.1.172.237; 17.1.172.238; 17.1.172.239; 17.1.172.154; 17.1.172.157; 17.1.172.166; 17.1.172.169; 17.1.172.172; 17.1.172.175; 17.1.172.240; 17.1.172.244; 17.1.175.228; 17.1.175.229; 17.1.175.230; 17.1.175.231; 17.1.175.236; 17.1.175.237; 17.1.175.238; 17.1.175.239; 17.1.175.154; 17.1.175.157; 17.1.175.166; 17.1.175.169; 17.1.175.172; 17.1.175.175; 17.1.175.240; 17.1.175.244; 17.1.240.228; 17.1.240.229; 17.1.240.230; 17.1.240.231; 17.1.240.236; 17.1.240.237; 17.1.240.238; 17.1.240.239; 17.1.240.154; 17.1.240.157; 17.1.240.166; 17.1.240.169; 17.1.240.172; 17.1.240.175; 17.1.240.240; 17.1.240.244; 17.1.244.228; 17.1.244.229; 17.1.244.230; 17.1.244.231; 17.1.244.236; 17.1.244.237; 17.1.244.238; 17.1.244.239; 17.1.244.154; 17.1.244.157; 17.1.244.166; 17.1.244.169; 17.1.244.172; 17.1.244.175; 17.1.244.240; 17.1.244.244;

Prodrugs of 17.T

17.J.228.228; 17.J.228.229; 17.J.228.230; 17.J.228.231; 17.J.228.236; 17.J.228.237; 17.J.228.238; 17.J.228.239; 17.J.228.154; 17.J.228.157; 17.J.228.166; 17.J.228.169; 17.J.228.172; 17.J.228.175; 17.J.228.240; 17.J.228.244; 17.J.229.228; 17.J.229.229; 17.J.229.230; 17J.229.231; 17.J.229.236; 17J.229.237; 17.J.229.238; 17J.229.239; 17J.229.154; 17J.229.157; 17J.229.166; 17J.229.169; 17J.229.172; 17J.229.175; 17J.229.240; 17J.229.244; 17J.230.228; 17J.230.229; 17J.230.230; 17J.230.231; 17J.230.236; 17J.230.237; 17J.230.238; 17J.230.239; 17J.230.154; 17J.230.157; 17J.230.166; 17J.230.169; 17J.230.172; 17.J.230.175; 17J.230.240; 17J.230.244; 17J.231.228; 17J.231.229; 17J.231.230; 17J.231.231; 17J.231.236; 17.J.231.237; 17J.231.238; 17.J.231.239; 17J.231.154; 17J.231.157; 17J.231.166; 17J.231.169; 17J.231.172; 17J.231.175; 17J.231.240; 17J.231.244; 17J.236.228; 17.J.236.229; 17J.236.230; 17J.236.231; 17J.236.236; 17J.236.237; 17J.236.238; 17J.236.239; 17J.236.154; 17J.236.157; 17J.236.166; 17J.236.169; 17J.236.172; 17J.236.175; 17.J.236.240; 17J.236.244; 17J.237.228; 17J.237.229; 17J.237.230; 17J.237.231; 17J.237.236; 17J.237.237; 17J.237.238; 17J.237.239; 17J.237.154; 17J.237.157; 17J.237.166; 17J.237.169; 17J.237.172; 17J.237.175; 17J.237.240; 17J.237.244; 17.J.238.228; 17J.238.229; 17J.238.230; 17J.238.231; 17J.238.236; 17J.238.237; 17J.238.238; 17J.238.239; 17J.238.154; 17J.238.157; 17J.238.166; 17J.238.169; 17J.238.172; 17J.238.175; 17J.238.240; 17J.238.244; 17J.239.228; 17J.239.229; 17.J.239.230; 17J.239.231; 17J.239.236; 17J.239.237; 17.J.239.238; 17J.239.239; 17J.239.154; 17J.239.157; 17.J.239.166; 17J.239.169; 17J.239.172; 17J.239.175; 17J.239.240; 17J.239.244; 17J.154.228; 17J.154.229; 17J.154.230; 17J.154.231; 17J.154.236; 17J.154.237; 17J.154.238; 17J.154.239; 17J.154.154; 17J.154.157; 17J.154.166; 17J.154.169; 17J.154.172; 17J.154.175; 17.J.154.240; 17J.154.244; 17J.157.228; 17J.157.229; 17.J.157.230; 17J.157.231; 17J.157.236; 17J.157.237; 17J.157.238; 17J.157.239; 17J.157.154; 17J.157.157; 17J.157.166; 17J.157.169; 17J.157.172; 17J.157.175; 17J.157.240; 17J.157.244; 17J.166.228; 17J.166.229; 17.J.166.230; 17J.166.231; 17J.166.236; 17.J.166.237; 17J.166.238; 17J.166.239; 17J.166.154; 17J.166.157; 17J.166.166; 17J.166.169; 17J.166.172; 17J.166.175; 17J.166.240; 17J.166.244; 17J.169.228; 17J.169.229; 17J.169.230; 17J.169.231; 17J.169.236; 17J.169.237; 17J.169.238; 17J.169.239; 17J.169.154; 17J.169.157; 17J.169.166; 17J.169.169; 17.J.169.172; 17J.169.175; 17J.169.240; 17J.169.244; 17J.172.228; 17J.172.229; 17J.172.230; 17J.172.231; 17J.172.236; 17J.172.237; 17J.172.238; 17J.172.239; 17J.172.154; 17J.172.157; 17J.172.166; 17J.172.169; 17J.172.172; 17J.172.175; 17J.172.240; 17J.172.244; 17J.175.228; 17J.175.229; 17J.175.230; 17J.175.231; 17J.175.236; 17J.175.237; 17J.175.238; 17J.175.239; 17J.175.154; 17J.175.157; 17.].175.166; 17J.175.169; 17J.175.172; 17J.175.175; 17J.175.240; 17J.175.244; 17J.240.228; 17J.240.229; 17J.240.230; 17J.240.231; 17J.240.236; 17J.240.237; 17J.240.238; 17J.240.239; 17J.240.154; 17J.240.157; 17J.240.166; 17J.240.169; 17J.240.172; 17J.240.175; 17.J.240.240; 17J.240.244; 17J.244.228; 17J.244.229; 17J.244.230; 17J.244.231; 17J.244.236; 17J.244.237; 17J.244.238; 17J.244.239; 17J.244.154; 17J.244.157; 17J.244.166; 17J.244.169; 17J.244.172; 17J.244.175; 17J.244.240; 17J.244.244;

Prodrugs of 17.L

17.L.228.228; 17.L.228.229; 17.L.228.230; 17.L.228.231; 17.L.228.236; 17.L.228.237; 17.L.228.238; 17.L.228.239; 17.L.228.154; 17.L.228.157; 17.L.228.166; 17.L.228.169; 17.L.228.172; 17.L.228.175; 17.L.228.240; 17.L.228.244; 17.L.229.228; 17.L.229.229; 17.L.229.230; 17.L.229.231; 17.L.229.236; 17.L.229.237; 17.L.229.238; 17.L.229.239; 17.L.229.154; 17.L.229.157; 17.L.229.166; 17.L.229.169; 17.L.229.172; 17.L.229.175; 17.L.229.240; 17.L.229.244; 17.L.230.228; 17.L.230.229; 17.L.230.230; 17.L.230.231; 17.L.230.236; 17.L.230.237; 17.L.230.238; 17.L.230.239; 17.L.230.154; 17.L.230.157; 17.L.230.166; 17.L.230.169; 17.L.230.172; 17.L.230.175; 17.L.230.240; 17.L.230.244; 17.L.231.228; 17.L.231.229; 17.L.231.230; 17.L.231.231; 17.L.231.236; 17.L.231.237; 17.L.231.238; 17.L.231.239; 17.L.231.154; 17.L.231.157; 17.L.231.166; 17.L.231.169; 17.L.231.172; 17.L.231.175; 17.L.231.240; 17.L.231.244; 17.L.236.228; 17.L.236.229; 17.L.236.230; 17.L.236.231; 17.L.236.236; 17.L.236.237; 17.L.236.238; 17.L.236.239; 17.L.236.154; 17.L.236.157; 17.L.236.166; 17.L.236.169; 17.L.236.172; 17.L.236.175; 17.L.236.240; 17.L.236.244; 17.L.237.228; 17.L.237.229; 17.L.237.230; 17.L.237.231; 17.L.237.236; 17.L.237.237; 17.L.237.238; 17.L.237.239; 17.L.237.154; 17.L.237.157; 17.L.237.166; 17.L.237.169; 17.L.237.172; 17.L.237.175; 17.L.237.240; 17.L.237.244; 17.L.238.228; 17.L.238.229; 17.L.238.230; 17.L.238.231; 17.L.238.236; 17.L.238.237; 17.L.238.238; 17.L.238.239; 17.L.238.154; 17.L.238.157; 17.L.238.166; 17.L.238.169; 17.L.238.172; 17.L.238.175; 17.L.238.240; 17.L.238.244; 17.L.239.228; 17.L.239.229; 17.L.239.230; 17.L.239.231; 17.L.239.236; 17.L.239.237; 17.L.239.238; 17.L.239.239; 17.L.239.154; 17.L.239.157; 17.L.239.166; 17.L.239.169; 17.L.239.172; 17.L.239.175; 17.L.239.240; 17.L.239.244; 17.L.154.228; 17.L.154.229; 17.L.154.230; 17.L.154.231; 17.L.154.236; 17.L.154.237; 17.L.154.238; 17.L.154.239; 17.L.154.154; 17.L.154.157; 17.L.154.166; 17.L.154.169; 17.L.154.172; 17.L.154.175; 17.L.154.240; 17.L.154.244; 17.L.157.228; 17.L.157.229; 17.L.157.230; 17.L.157.231; 17.L.157.236; 17.L.157.237; 17.L.157.238; 17.L.157.239; 17.L.157.154; 17.L.157.157; 17.L.157.166; 17.L.157.169; 17.L.157.172; 17.L.157.175; 17.L.157.240; 17.L.157.244; 17.L.166.228; 17.L.166.229; 17.L.166.230; 17.L.166.231; 17.L.166.236; 17.L.166.237; 17.L.166.238; 17.L.166.239; 17.L.166.154; 17.L.166.157; 17.L.166.166; 17.L.166.169; 17.L.166.172; 17.L.166.175; 17.L.166.240; 17.L.166.244; 17.L.169.228; 17.L.169.229; 17.L.169.230; 17.L.169.231; 17.L.169.236; 17.L.169.237; 17.L.169.238; 17.L.169.239; 17.L.169.154; 17.L.169.157; 17.L.169.166; 17.L.169.169; 17.L.169.172; 17.L.169.175; 17.L.169.240; 17.L.169.244; 17.L.172.228; 17.L.172.229; 17.L.172.230; 17.L.172.231; 17.L.172.236; 17.L.172.237; 17.L.172.238; 17.L.172.239; 17.L.172.154; 17.L.172.157; 17.L.172.166; 17.L.172.169; 17.L.172.172; 17.L.172.175; 17.L.172.240; 17.L.172.244; 17.L.175.228; 17.L.175.229; 17.L.175.230; 17.L.175.231; 17.L.175.236; 17.L.175.237; 17.L.175.238; 17.L.175.239; 17.L.175.154; 17.1.175.157; 17.L.175.166; 17.L.175.169; 17.L.175.172; 17.L.175.175; 17.L.175.240; 17.L.175.244; 17.L.24Q.228; 17.L.240.229; 17.L.240.230; 17.L.240.231; 17.L.240.236; 17.L.240.237; 17.L.240.238; 17.L.240.239; 17.L.240.154; 17.L.240.157; 17.L.240.166; 17.L.240.169; 17.L.240.172; 17.L.240.175; 17.L.240.240; 17.L.240.244; 17.L.244.228; 17.L.244.229; 17.L.244.230; 17.L.244.231; 17.L.244.236; 17.L.244.237; 17.L.244.238; 17.L.244.239; 17.L.244.154; 17.L.244.157; 17.L.244.166; 17.L.244.169; 17.L.244.172; 17.L.244.175; 17.L.244.240; 17.L.244.244;

Prodrugs of 17.O

17.O.228.228; 17.Q.228.229; 17.Q.228.230; 17.O.228.231; 17.O.228.236; 17.O.228.237; 17.O.228.238; 17.O.228.239; 17.0.228.154; 17.O.228.157; 17.O.228.166; 17.O.228.169; 17.O.228.172; 17.O.228.175; 17.O.228.240; 17.O.228.244; 17.O.229.228; 17.O.229.229; 17.Q.229.230; 17.Q.229.231; 17.O.229.236; 17.O.229.237; 17.O.229.238; 17.O.229.239; 17.O.229.154; 17.O.229.157; 17.O.229.166; 17.O.229.169; 17.O.229.172; 17.O.229.175; 17.O.229.240; 17.O.229.244; 17.O.230.228; 17.O.230.229; 17.O.230.230; 17.O.230.231; 17.O.230.236; 17.O.230.237; 17.O.230.238; 17.O.230.239; 17.O.230.154; 17.O.230.157; 17.O.230.166; 17.O.230.169; 17.O.230.172; 17.O.230.175; 17.O.230.240; 17.O.230.244; 17.O.231.228; 17.O.231.229; 17.O.231.230; 17.O.231.231; 17.O.231.236; 17.O.231.237; 17.O.231.238; 17.O.231.239; 17.O.231.154; 17.O.231.157; 17.O.231.166; 17.O.231.169; 17.O.231.172; 17.O.231.175; 17.O.231.240; 17.O.231.244; 17.O.236.228; 17.O.236.229; 17.O.236.230; 17.O.236.231; 17.O.236.236; 17.O.236.237; 17.O.236.238; 17.O.236.239; 17.O.236-154; 17.O.236.157; 17.O.236.166; 17.O.236.169; 17.O.236.172; 17.O.236.175; 17.O.236.240; 17.O.236.244; 17.O.237.228; 17.O.237.229; 17.O.237.230; 17.O.237.231; 17.O.237.236; 17.O.237.237; 17.O.237.238; 17.O.237.239; 17.O.237.154; 17.O.237.157; 17.O.237.166; 17.O.237.169; 17.O.237.172; 17.O.237.175; 17.O.237.240; 17.O.237.244; 17.O.238.228; 17.O.238.229; 17.O.238.23Q; 17.O.238.231; 17.O.238.236; 17.O.238.237; 17.O.238.238; 17.O.238.239; 17.O.238.154; 17.O.238.157; 17.O.238.166; 17.O.238.169; 17.O.238.172; 17.O.238.175; 17.O.238.240; 17.O.238.244; 17.O.239.228; 17.O.239.229; 17.O.239.230; 17.O.239.231; 17.O.239.236; 17.O.239.237; 17.O.239.238; 17.O.239.239; 17.O.239.154; 17.O.239.157; 17.O.239.166; 17.O.239.169; 17.O.239.172; 17.O.239.175; 17.O.239.240; 17.O.239.244; 17.O.154.228; 17.O.154.229; 17.O.154.230; 17.O.154.231; 17.O.154.236; 17.O.154.237; 17.O.154.238; 17.O.154.239; 17.O.154.154; 17.O.154.157; 17.O.154.166; 17.O.154.169; 17.O.154.172; 17.O.154.175; 17.O.154.240; 17.O.154.244; 17.O.157.228; 17.O.157.229; 17.O.157.230; 17.O.157.231; 17.O.157.236; 17.O.157.237; 17.O.157.238; 17.O.157.239; 17.O.157.154; 17.O.157.157; 17.O.157.166; 17.O.157.169; 17.O.157.172; 17.O.157.175; 17.O.157.240; 17.O.157.244; 17.O.166.228; 17.O.166.229; 17.O.166.230; 17.O.166.231; 17.O.166.236; 17.O.166.237; 17.O.166.238; 17.O.166.239; 17.O.166.154; 17.O.166.157; 17.O.166.166; 17.O.166.169; 17.O.166.172; 17.O.166.175; 17.O.166.240; 17.O.166.244; 17.O.169.228; 17.O.169.229; 17.O.169.230; 17.O.169.231; 17.Q.169.236; 17.O.169.237; 17.O.169.238; 17.O.169.239; 17.O.169.154; 17.O.169.157; 17.O.169.166; 17.O.169.169; 17.O.169.172; 17.O.169.175; 17.O.169.240; 17.O.169.244; 17.O.172.228; 17.O.172.229; 17.O.172.230; 17.O.172.231; 17.O.172.236; 17.O.172.237; 17.O.172.238; 17.O.172.239; 17.O.172.154; 17.O.172.157; 17.O.172.166; 17.O.172.169; 17.O.172.172; 17.O.172.175; 17.O.172.240; 17.O.172.244; 17.O.175.228; 17.O.175.229; 17.O.175.230; 17.O.175.231; 17.O.175.236; 17.O.175.237; 17.O.175.238; 17.O.175.239; 17.O.175.154; 17.O.175.157; 17.O.175.166; 17.O-175.169; 17.O.175.172; 17.O.175.175; 17.O.175.240; 17.O.175.244; 17.O.240.228; 17.O.240.229; 17.O.240.230; 17.O.240.231; 17.O.240.236; 17.O.240.237; 17.O.240.238; 17.O.240.239; 17.O.240.154; 17.O.240.157; 17.O.240.166; 17.O.240.169; 17.O.240.172; 17.O.240.175; 17.O.240.240; 17.O.240.244; 17.O.244.228; 17.O.244.229; 17.O.244.230; 17.O.244.231; 17.O.244.236; 17.O.244.237; 17.O.244.238; 17.O.244.239; 17.O.244.154; 17.O.244.157; 17.O.244.166; 17.O.244.169; 17.O.244.172; 17.O.244.175; 17.O.244.240; 17.O.244.244;

Prodrugs of 17.P

17.P.228.228; 17.P.228.229; 17.P.228.230; 17.P.228.231; 17.P.228.236; 17.P.228.237; 17.P.228.238; 17.P.228.239; 17.P.228.154; 17.P.228.157; 17.P.228.166; 17.P.228.169; 17.P.228.172; 17.P.228.175; 17.P.228.240; 17.P.228.244; 17.P.229.228; 17.P.229.229; 17.P.229.230; 17.P.229.231; 17.P.229.236; 17.P.229.237; 17.P.229.238; 17.P.229.239; 17.P.229.154; 17.P.229.157; 17.P.229.166; 17.P.229.169; 17.P.229.172; 17.P.229.175; 17.P.229.24Q; 17.P.229.244; 17.P.230.228; 17.P.230.229; 17.P.230.230; 17.P.230.231; 17.P.230.236; 17.P.230.237; 17.P.23Q.238; 17.P.230.239; 17.P.230.154; 17.P.230.157; 17.P.230.166; 17.P.230.169; 17.P.230.172; 17.P.230.175; 17.P.230.240; 17.P.230.244; 17.P.231.228; 17.P.231.229; 17.P.231.230; 17.P.231.231; 17.P.231.236; 17.P.231.237; 17.P.231.238; 17.P.231.239; 17.P.231.154; 17.P.231.157; 17.P.231.166; 17.P.231.169; 17.P.231.172; 17.P.231.175; 17.P.231.240; 17.P.231.244; 17.P.236.228; 17.P.236.229; 17.P.236.230; 17.P.236.231; 17.P.236.236; 17.P.236.237; 17.P.236.238; 17.P.236.239; 17.P.236.154; 17.P.236.157; 17.P.236.166; 17.P.236.169; 17.P.236.172; 17.P.236.175; 17.P.236.240; 17.P.236.244; 17.P.237.228; 17.P.237.229; 17.P.237.230; 17.P.237.231; 17.P.237.236; 17.P.237.237; 17.P.237.238; 17.P.237.239; 17.P.237.154; 17.P.237.157; 17.P.237.166; 17.P.237.169; 17.P.237.172; 17.P.237.175; 17.P.237.240; 17.P.237.244; 17.P.238.228; 17.P.238.229; 17.P.238.230; 17.P.238.231; 17.P.238.236; 17.P.238.237; 17.P.238.238; 17.P.238.239; 17.P.238.154; 17.P.238.157; 17.P.238.166; 17.P.238.169; 17.P.238.172; 17.P.238.175; 17.P.238.240; 17.P.238.244; 17.P.239.228; 17.P.239.229; 17.P.239.230; 17.P.239.231; 17.P.239.236; 17.P.239.237; 17.P.239.238; 17.P.239.239; 17.P.239.154; 17.P.239.157; 17.P.239.166; 17.P.239.169; 17.P.239.172; 17.P.239.175; 17.P.239.240; 17.P.239.244; 17.P.154.228; 17.P.154.229; 17.P.154.230; 17.P.154.231; 17.P.154.236; 17.P.154.237; 17.P.154.238; 17.P.154.239; 17.P.154.154; 17.P.154.157; 17.P.154.166; 17.P.154.169; 17.P.154.172; 17.P.154.175; 17.P.154.240; 17.P.154.244; 17.P.157.228; 17.P.157.229; 17.P.157.230; 17.P.157.231; 17.P.157.236; 17.P.157.237; 17.P.157.238; 17.P.157.239; 17.P.157.154; 17.P.157.157; 17.P.157.166; 17.P.157.169; 17.P.157.172; 17.P.157.175; 17.P.157.240; 17.P.157.244; 17.P.166.228; 17.P.166.229; 17.P.166.230; 17.P.166.231; 17.P.166.236; 17.P.166.237; 17.P.166.238; 17.P.166.239; 17.P.166.154; 17.P.166.157; 17.P.166.166; 17.P.166.169; 17.P.166.172; 17.P.166.175; 17.P.166.240; 17.P.166.244; 17.P.169.228; 17.P.169.229; 17.P.169.230; 17.P.169.231; 17.P.169.236; 17.P.169.237; 17.P.169.238; 17.P.169.239; 17.P.169.154; 17.P.169.157; 17.P.169.166; 17.P.169.169; 17.P.169.172; 17.P.169.175; 17.P.169.240; 17.P.169.244; 17.P.172.228; 17.P.172.229; 17.P.172.230; 17.P.172.231; 17.P.172.236; 17.P.172.237; 17.P.172.238; 17.P.172.239; 17.P.172.154; 17.P.172.157; 17.P.172.166; 17.P.172.169; 17.P.172.172; 17.P.172.175; 17.P.172.240; 17.P.172.244; 17.P.175.228; 17.P.175.229; 17.P.175.230; 17.P.175.231; 17.P.175.236; 17.P.175.237; 17.P.175.238; 17.P.175.239; 17.P.175.154; 17.P.175.157; 17.P.175.166; 17.P.175.169; 17.P.175.172; 17.P.175.175; 17.P.175.240; 17.P.175.244; 17.P.240.228; 17.P.240.229; 17.P.240.230; 17.P.240.231; 17.P.240.236; 17.P.240.237; 17.P.240.238; 17.P.240.239; 17.P.240.154; 17.P.240.157; 17.P.240.166; 17.P.240.169; 17.P.240.172; 17.P.240.175; 17.P.240.240; 17.P.240.244; 17.P.244.228; 17.P.244.229; 17.P.244.230; 17.P.244.231; 17.P.244.236; 17.P.244.237; 17.P.244.238; 17.P.244.239; 17.P.244.154; 17.P.244.157; 17.P.244.166; 17.P.244.169; 17.P.244.172; 17.P.244.175; 17.P.244.240; 17.P.244.244;

Prodrugs of 17.U

17.U.228.228; 17.U.228.229; 17.U.228.230; 17.U.228.231; 17.U.228.236; 17.U.228.237; 17.U.228.238; 17.U.228.239; 17.U.228.154; 17.U.228.157; 17.U.228.166; 17.U.228.169; 17.U.228.172; 17.U.228.175; 17.U.228.240; 17.U.228.244; 17.U.229.228; 17.U.229.229; 17.U.229.230; 17.U.229.231; 17.U.229.236; 17.U.229.237; 17.U.229.238; 17.U.229.239; 17.U.229.154; 17.U.229.157; 17.U.229.166; 17.U.229.169; 17.U.229.172; 17.U.229.175; 17.U.229.240; 17. ,U. ,229.244; 17.U.23Q.228; 17.U.230.229; 17.U.230.230; 17.U.230.231; 17.U.230.236; 17.U.230.237; 17.U.230.238; 17.U.230.239; 17.U.230.154; 17.U.230.157; 17.U.230.166; 17.U.230.169; 17.U.230.172; 17.U.230.175; 17.U.230.240; 17.U.230.244; 17.U.231.228; 17.U.231.229; 17.U.231.230; 17.U.231.231; 17.U.231.236; 17.U.231.237; 17.U.231.238; 17.U.231.239; 17.U.231.154; 17.U.231.157; 17.U.231.166; 17.U.231.169; 17.U.231.172; 17.U.231.175; 17.U.231.240; 17.U.231.244; 17.U.236.228; 17.U.236.229; 17.U.236.23Q; 17.U.236.231; 17.U.236.236; 17.U.236.237; 17.U.236.238; 17.U.236.239; 17.U.236.154; 17.U.236.157; 17.U.236.166; 17.U.236.169; 17.U.236.172; 17.U.236.175; 17.U.236.240; 17.U.236.244; 17.U.237.228; 17.U.237.229; 17.U.237.230; 17.U.237.231; 17.U.237.236; 17.U.237.237; 17.U.237.238; 17.U.237.239; 17.U.237.154; 17.U.237.157; 17.U.237.166; 17.U.237.169; 17.U.237.172; 17.U.237.175; 17.U-237.240; 17.U.237.244; 17.U.238.228; 17.U.238.229; 17.U.238.230; 17.U.238.231; 17.U.238.236; 17.U.238.237; 17.U.238.238; 17.U.238.239; 17.U.238.154; 17.U.238.157; 17.U.238.166; 17.U.238.169; 17.U.238.172; 17.U.238.175; 17.U.238.240; 17.U.238.244; 17.U.239.228; 17.U.239.229; 17.U.239.230; 17.U.239.231; 17.U.239.236; 17.U.239.237; 17.U.239.238; 17.U.239.239; 17.U.239.154; 17.U.239.157; 17.U.239.166; 17.U.239.169; 17.U.239.172; 17.U.239.175; 17.U.239.240; 17.U.239.244; 17.U.154.228; 17.U.154.229; 17.U.154.230; 17.U.154.231; 17.U.154.236; 17.U.154.237; 17.U.154.238; 17.U.154.239; 17.U.154.154; 17.U.154.157; 17.U.154.166; 17.U.154.169; 17.U.154.172; 17.U.154.175; 17.U.154.240; 17.U.154.244; 17.U.157.228; 17.U.157.229; 17.U.157.230; 17.U.157.231; 17.U.157.236; 17.U.157.237; 17.U.157.238; 17.U.157.239; 17.U.157.154; 17.U.157.157; 17.U.157.166; 17.U.157.169; 17.U.157.172; 17.U.157.175; 17.U.157.240; 17.U.157.244; 17.U.166.228; 17.U.166.229; 17.U.166.230; 17.U.166.231; 17.U.166.236; 17.U.166.237; 17.U.166.238; 17.U.166.239; 17.U.166.154; 17.U.166.157; 17.U.166.166; 17.U.166.169; 17.U.166.172; 17.U.166.175; 17.U.166.240; 17.U.166-244; 17.U.169.228; 17.U.169.229; 17.U.169.230; 17.U.169.231; 17.U.169.236; 17.U.169.237; 17.U.169.238; 17.U.169.239; 17.U.169.154; 17.U.169.157; 17.U.169.166; 17.U.169.169; 17.U.169.172; 17.U.169.175; 17.U.169.240; 17.U.169.244; 17.U172.228; 17.U.172.229; 17.U.172.230; 17.U.172.231; 17.U.172.236; 17.U.172.237; 17.U.172.238; 17.U.172.239; 17.U.172.154; 17.U.172.157; 17.U.172.166; 17.U.172.169; 17.U.172.172; 17.U.172.175; 17.U.172.240; 17.U.172.244; 17.U.175.228; 17.U.175.229; 17.U.175.230; 17.U.175.231; 17.U.175-236; 17.U.175.237; 17.U.175.238; 17.U.175.239; 17.U.175.154; 17.U.175.157; 17.U.175.166; 17.U.175.169; 17.U.175.172; 17.U.175.175; 17.U.175.24Q; 17.U.175.244; 17.U.240.228; 17.U.240.229; 17.U.240.230; 17.U.240.231; 17.U.240.236; 17.U.240.237; 17.U.240.238; 17.U.240.239; 17.U.240.154; 17.U.240.157; 17.U.240.166; 17.U.240.169; 17.U.240.172; 17.U.240.175; 17.U.240.240; 17.U.240.244; 17.U.244.228; 17.U.244.229; 17.U.244.230; 17.U.244.231; 17.U.244.236; 17.U.244.237; 17.U.244.238; 17.U.244.239; 17.U.244.154; 17.U.244.157; 17.U.244.166; 17.U.244.169; 17.U.244.172; 17.U.244.175; 17.U.244.240; 17.U.244.244;

Prodrugs of 17.CD

17.CD.228.228; 17.CD.228.229; 17.CD.228.230; 17.CD.228.231; 17.CD.228.236; 17.CD.228.237; 17.CD.228.238; 17.CD.228.239; 17.CD.228.154; 17.CD.228.157; 17.CD.228.166; 17.CD.228.169; 17.CD.228.172; 17.CD.228.175; 17.CD.228.240; 17.CD.228.244; 17. CD.229.228; 17. CD.229.229; 17.CD.229.230; 17.CD.229.231; 17.CD.229.236; 17.CD.229.237; 17.CD.229.238; 17.CD.229.239; 17.CD.229.154; 17.CD.229.157; 17. CD.229.166; 17. CD.229.169; 17. CD.229.172; 17. CD.229.175; 17.CD.229.240; 17.CD.229.244; 17.CD.230.228; 17.CD.230.229; 17.CD.230.230; 17.CD.230.231; 17.CD.230.236; 17.CD.230.237; 17.CD.230.238; 17.CD.230.239; 17.CD.230.154; 17.CD.230.157; 17.CD.230.166; 17.CD.230.169; 17.CD.230.172; 17.CD.230.175; 17.CD.230.240; 17.CD.230.244; 17.CD.231.228; 17.CD.231.229; 17.CD.231.230; 17.CD.231.231; 17.CD.231.236; 17.CD.231.237; 17.CD.231.238; 17.CD.231.239; 17.CD.231.154; 17.CD.231.157; 17.CD.231.166; 17.CD.231.169; 17.CD.231.172; 17.CD.231.175; 17.CD.231.240; 17.CD.231.244; 17.CD.236.228; 17. CD.236.229; 17.CD.236.230; 17.CD.236.231; 17.CD.236.236; 17.CD.236.237; 17.CD.236.238; 17. CD.236.239; 17.CD.236.154; 17.CD.236.157; 17.CD.236.166; 17.CD.236.169; 17.CD.236.172; 17.CD.236.175; 17.CD.236.240; 17.CD.236.244; 17.CD.237.228; 17.CD.237.229; 17.CD.237.230; 17.CD.237.231; 17.CD.237.236; 17.CD.237.237; 17.CD.237.238; 17.CD.237.239; 17.CD.237.154; 17.CD.237.157; 17.CD.237.166; 17.CD.237.169; 17.CD.237.172; 17.CD.237.175; 17.CD.237.240; 17.CD.237.244; 17.CD.238.228; 17.CD.238.229; 17.CD.238.230; 17.CD.238.231; 17.CD.238.236; 17.CD.238.237; 17.CP.238.238; 17.CD.238.239; 17.CD.238.154; 17.CD.238.157; 17.CD.238.166; 17.CD.238.169; 17.CD.238.172; 17.CD.238.175; 17.CD.238.240; 17.CD.238.244; 17.CD.239.228; 17.CD.239.229; 17.CD.239.230; 17.CD.239.231; 17.CD.239.236; 17.CD.239.237; 17.CD.239.238; 17.CD.239.239; 17. CD.239.154:; 17.CD.239.157; 17. CD.239.166; 17..CD..239.169; 17.CD.239.172; 17.CD.239.175; 17.CD.239.240; 17.CD.239.244; 17.CD.154.228; 17.CD.154.229; 17.CD.154.230; 17.CD.154.231; 17.CD.154.236; 17. CD.154.237; 17.CD.154.238; 17.CD.154.239; 17.CD.154.154; 17.CD.154.157; 17.CD.154.166; 17.CD.154.169; 17.CD.154.172; 17.CD.154.175; 17.CD.154.240; 17.CD.154.244; 17.CD.157.228; 17.CD.157.229; 17.CD.157.230; 17.CD.157.231; 17.CD.157.236; 17.CD.157.237; 17.CD.157.238; 17.CD.157.239; 17.CD.157.154; 17.CD.157.157; 17.CD.157.166; 17.CD.157.169; 17.CD.157.172; 17.CD.157.175; 17.CD.157.240; 17.CD.157.244; 17.CD.166.228; 17.CD.166.229; 17.CD.166.230; 17.CD.166.231; 17. CD.166.236; 17.CD.166.237; 17.CD.166.238; 17.CD.166.239; 17.CD.166.154; 17.CD.166.157; 17.CD.166.166; 17. CD.166.169; 17. CD.166.172; 17.CD.166.175; 17.CD.166.240; 17.CD.166.244; 17.CD.169.228; 17.CD.169.229; 17.CD.169.230; 17.CD.169.231; 17.CD.169.236; 17.CD.169.237; 17.CD.169.238; 17.CD.169.239; 17.CD.169.154; 17.CD.169.157; 17.CD.169.166; 17.CD.169.169; 17.CD.169.172; 17.CD.169.175; 17.CD.169.240; 17.CD.169.244; 17. CD.172.228; 17.CD.172.229; 17.CD.172.230; 17.CD.172.231; 17.CD.172.236; 17.CD.172.237; 17.CD.172.238; 17.CD.172.239; 17.CD.172.154; 17.CD.172.157; 17.CD.172.166; 17. CD.172.169; 17.CD.172.172; 17.CD.172.175; 17.CD.172.240; 17.CD.172.244; 17.CD.175.228; 17.CD.175.229; 17.CD.175.230; 17.CD.175.231; 17.CD.175.236; 17.CD.175.237; 17.CD.175.238; 17.CD.175.239; 17.CD.175.154; 17.CD.175.157; 17.CD.175.166; 17.CD.175.169; 17.CD.175.172; 17.CD.175.175; 17.CD.175.240; 17.CD.175.244; 17.CD.240.228; 17.CD.240.229; 17.CD.240.230; 17.CD.240.231; 17.CD.240.236; 17.CD.240.237; 17.CD.240.238; 17.CD.240.239; 17.CD.240.154; 17.CD.240.157; 17.CD.240.166; 17.CD.240.169; 17.CD.240.172; 17.CD.240.175; 17.CD.240.240; 17.CD.240.244; 17.CD.244.228; 17.CD.244.229; 17.CD.244.230; 17.CD.244.231; 17.CD.244.236; 17.CD.244.237; 17.CD.244.238; 17.CD.244.239; 17.CD.244.154; 17.CD.244.157; 17.CD.244.166; 17.CD.244.169; 17.CD.244.172; 17.CD.244.175; 17.CD.244.240; 17.CD.244.244;

Prodrugs of 17.EB

17.EB.228.228; 17.EB.228.229; 17.EB.228.230; 17.EB.228.231; 17.EB.228.236; 17.EB.228.237; 17.EB.228.238; 17.EB.228.239; 17.EB.228.154; 17.EB.228.157; 17.EB.228.166; 17.EB.228.169; 17.EB.228.172; 17.EB.228.175; 17.EB.228.240; 17.EB.228.244; 17.EB.229.228; 17.EB.229.229; 17.EB.229.230; 17.EB.229.231; 17.EB.229.236; 17.EB.229.237; 17.EB.229.238; 17.EB.229.239; 17.EB.229.154; 17.EB.229.157; 17.EB.229.166; 17.EB.229.169; 17. ΕQ.229.172; 17.EB.229.175; 17.EB.229.240; 17.EB.229.244; 17.EB.230.228; 17.EB.230.229; 17.EB.230.230; 17.EB.230.231; 17.EB.230.236; 17.EB.230.237; 17.EB.230.238; 17.EB.230.239; 17.EB.230.154; 17.EB.230.157; 17.EB.23Q.166; 17.EB.230.169; 17.EB.230.172; 17.EB.230.175; 17.EB.230.240; 17.EB.230.244; 17.EB.231.228; 17.EB.231.229; 17.EB.231.230; 17.EB.231.231; 17.EB.231.236; 17.EB.231.237; 17.EB.231.238; 17.EB.231.239; 17.EB.231.154; 17.EB.231.157; 17.EB.231.166; 17.EB.231.169; 17.EB.231.172; 17.EB.231.175; 17.EB.231.240; 17.EB.231.244; 17.EB.236.228; 17.EB.236.229; 17.EB.236.230; 17.EB.236.231; 17.EB.236.236; 17.EB.236.237; 17.EB.236.238; 17.EB.236.239; 17.EB.236.154; 17.EB.236.157; 17.EB.236.166; 17.EB.236.169; 17.EB.236.172; 17.EB.236.175; 17.EB.236.240; 17.EB.236.244; 17.EB.237.228; 17.EB.237.229; 17.EB.237.230; 17.EB.237.231; 17.EB.237.236; 17.EB.237.237; 17.EB.237.238; 17.EB.237.239; 17.EB.237.154; 17.EB.237.157; 17.EB.237.166; 17.EB.237.169; 17.EB.237.172; 17.EB.237.175; 17.EB.237.240; 17.EB.237.244; 17.EB.238.228; 17.EB.238.229; 17.EB.238.230; 17.EB.238.231; 17.EB.238.236; 17.EB.238.237; 17.EB.238.238; 17.EB.238.239; 17.EB.238.154; 17.EB.238.157; 17.EB.238.166; 17.EB.238.169; 17.EB.238.172; 17.EB.238.175; 17.EB.238.240; 17.EB.238.244; 17.EB.239.228; 17.EB.239.229; 17.EB.239.230; 17.EB.239.231; 17.EB.239.236; 17.EB.239.237; 17.EB.239.238; 17.EB.239.239; 17.EB.239.154; 17.EB.239.157; 17.EB.239.166; 17.EB.239.169; 17.EB.239.172; 17.EB.239.175; 17.EB.239.240; 17.EB.239.244; 17.EB.154.228; 17.EB.154.229; 17.EB.154.230; 17.EB.154.231; 17.EB.154.236; 17.EB.154.237; 17.EB.154.238; 17.EB.154.239; 17.EB.154.154; 17.EB.154.157; 17.EB.154.166; 17.EB.154.169; 17.EB.154.172; 17.EB.154.175; 17.EB.154.240; 17.EB.154.244; 17.EB.157.228; 17.EB.157.229; 17.EB.157.230; 17.EB.157.231; 17.EB.157.236; 17.EB.157.237; 17.EB.157.238; 17.EB.157.239; 17.EB.157.154; 17.EB.157.157; 17.EB.157.166; 17.EB.157.169; 17.EB.157.172; 17.EB.157.175; 17.EB.157.240; 17.EB.157.244; 17.EB.166.228; 17.EB.166.229; 17.EB.166.230; 17.EB.166.231; 17.EB.166.236; 17.EB.166.237; 17.EB.166.238; 17.EB.166.239; 17.EB.166.154; 17.EB.166.157; 17.EB.166.166; 17.EB.166.169; 17.EB.166.172; 17.EB.166.175; 17.EB.166.240; 17.EB.166.244; 17.EB.169.228; 17.EB.169.229; 17.EB.169.230; 17.EB.169.231; 17.EB.169.236; 17.EB.169.237; 17.EB.169.238; 17.EB.169.239; 17.EB.169.154; 17.EB.169.157; 17.EB.169.166; 17.EB.169.169; 17.EB.169.172; 17.EB.169.175; 17.EB.169.240; 17.EB.169.244; 17.EB.172.228; 17.EB.172.229; 17.EB.172.230; 17.EB.172.231; 17.EB.172.236; 17.EB.172.237; 17.EB.172.238; 17.EB.172.239; 17.EB.172.154; 17.EB.172.157; 17.EB.172.166; 17.EB.172.169; 17. EB.172.172; 17.EB.172.175; 17.EB.172.240; 17.EB.172.244; 17.EB.175.228; 17.EB.175.229; 17.EB.175.230; 17.EB.175.231; 17.EB.175.236; 17.EB.175.237; 17.EB.175.238; 17.EB.175.239; 17.EB.175.154; 17.EB.175.157; 17.EB.175.166; 17. EB.175.169; 17.EB.175.172; 17.EB.175.175; 17.EB.175.240; 17.EB.175.244; 17.EB.240.228; 17.EB.240.229; 17.EB.240.230; 17.EB.240.231; 17.EB.240.236; 17.EB.240.237; 17.EB.240.238; 17.EB.240.239; 17.EB.240.154; 17.EB.240.157; 17.EB.240.166; 17.EB.240.169; 17.EB.240.172; 17.EB.240.175; 17.EB.240.240; 17.EB.240.244; 17.EB.244.228; 17.EB.244.229; 17.EB.244.230; 17.EB.244.231; 17.EB .244.236; 17.EB.244.237; 17.EB.244.238; 17.EB.244.239; 17.EB.244.154; 17.EB.244.157; 17.EB.244.166; 17.EB.244.169; 17.EB.244.172; 17.EB.244.175; 17.EB.244.240; 17.EB.244.244; Prodrugs of 18.B

18.B.228.228; 18.B.228.229; 18.B.228.230; 18.B.228.231; 18.B.228.236; 18.B.228.237; 18.B.228.238; 18.B.228.239; 18.B.228.154; 18.B.228.157; 18.B.228.166; 18.B.228.169; 18.B.228.172; 18.B.228.175; 18.B.228.240; 18.B.228.244; 18.B.229.228; 18.B.229.229; 18.B.229.230; 18.B.229.231; 18.B.229.236; 18.B.229.237; 18.B.229.238; 18.B.229.239; 18.B.229.154; 18.B.229.157; 18.B.229.166; 18.B.229.169; 18.B.229.172; 18.B.229.175; 18.B.229.240; 18.B.229.244; 18.B.230.228; 18.B.230.229; 18.B.230.230; 18.B.230.231; 18.B.23Q.236; 18.B.230.237; 18.B.230.238; 18.B.230.239; 18.B.230.154; 18.B.230.157; 18.B.230.166; 18.B.230.169; 18.B.230.172; 18.B.230.175; 18.B.230.240; 18.B.230.244; 18.B.231.228; 18.B.231.229; 18.B.231.230; 18.B.231.231; 18.B.231.236; 18.B.231.237; 18.B.231.238; 18.B.231.239; 18.B.231.154; 18.B.231.157; 18.B.231.166; 18.B.231.169; 18.B.231.172; 18.B.231.175; 18.B.231.240; 18.B.231.244; 18.B.236.228; 18.B.236.229; 18.B.236.230; 18.B.236.231; 18.B.236.236; 18.B.236.237; 18.B.236.238; 18.B.236.239; 18.B.236.154; 18.B.236.157; 18.B.236.166; 18.B.236.169; 18.B.236.172; 18.B.236.175; 18.B.236.240; 18.B.236.244; 18.B.237.228; 18.B.237.229; 18.B.237.230; 18.B.237.231; 18.B.237.236; 18.B.237.237; 18.B.237.238; 18.B.237.239; 18.B.237.154; 18.B.237.157; 18.B.237.166; 18.B.237.169; 18.B.237.172; 18.B.237.175; 18.B.237.240; 18.B.237.244; 18.B.238.228; 18.B.238.229; 18.B.238.230; 18.B.238.231; 18.B.238.236; 18.B.238.237; 18.B.238.238; 18.B.238.239; 18.B.238.154; 18.B.238.157; 18.B.238.166; 18.B.238.169; 18.B.238.172; 18.B.238.175; 18.B.238.240; 18.B.238.244; 18.B.239.228; 18.B.239.229; 18.B.239.230; 18.B.239.231; 18.B.239.236; 18.B. ,239..237; 18.B.239.238; 18.B.239.239; 18.B.239.154; 18.B.239.157; 18.B.239.166; 18.B.239.169; 18.B.239.172; 18.B.239.175; 18.B.239.240; 18.B.239.244; 18.B.154.228; 18.B.154.229; 18.B.154.230; 18.B.154.231; 18.B.154.236; 18.B.154.237; 18.B.154.238; 18.B.154.239; 18.B.154.154; 18.B.154.157; 18.B.154.166; 18.B.154.169; 18.B.154.172; 18.B.154.175; 18.B.154.240; 18.B.154.244; 18.B.157.228; 18.B.157.229; 18.B.157.230; 18.B.157.231; 18.B.157.236; 18.B.157.237; 18.B.157.238; 18.B.157.239; 18.B.157.154; 18.B.157.157; 18.B.157.166; 18.B.157.169; 18.B.157.172; 18.B.157.175; 18.B.157.240; 18.B.157.244; 18.B.166.228; 18.B.166.229; 18.B.166.230; 18.B.166.231; 18.B.166.236; 18.B.166.237; 18.B.166.238; 18.B.166.239; 18.B.166.154; 18.B.166.157; 18.B.166.166; 18.B.166.169; 18.B.166.172; 18.B.166.175; 18.B.166.240; 18.B.166.244; 18.B.169.228; 18.B.169.229; 18.B.169.230; 18.B.169.231; 18.B.169.236; 18.B.169.237; 18.B.169.238; 18.B.169.239; 18.B.169.154; 18.B.169.157; 18.B.169.166; 18.B.169.169; 18.B.169.172; 18.B.169.175; 18.B.169.240; 18.B.169.244; 18.B.172.228; 18.B.172.229; 18.B.172.230; 18.B.172.231; 18.B.172.236; 18.B.172.237; 18.B.172.238; 18.B.172.239; 18.B.172.154; 18.B.172.157; 18.B.172.166; 18.B.172.169; 18.B.172.172; 18.B.172.175; 18.B.172.240; 18.B.172.244; 18.B.175.228; 18.B.175.229; 18.B.175.230; 18.B.175.231; 18.B.175.236; 18.B.175.237; 18.B.175.238; 18.B.175.239; 18.B.175.154; 18.B.175.157; 18.B.175.166; 18.B.175.169; 18.B.175.172; 18.B.175.175; 18.B.175.240; 18.B.175.244; 18.B.240.228; 18.B.240.229; 18.B.240.230; 18.B.240.231; 18.B.240.236; 18.B.240.237; 18.B.240.238; 18.B.240.239; 18.B.240.154; 18.B.240.157; 18.B.240.166; 18.B.240.169; 18.B.240.172; 18.B.240175; 18.B.240.240; 18.B.240.244; 18.B.244.228; 18.B.244.229; 18.B.244.230; 18.B.244.231; 18.B.244.236; 18.B.244.237; 18.B.244.238; 18.B.244.239; 18.B.244.154; 18.B.244.157; 18.B.244.166; 18.B.244.169; 18.B.244.172; 18.B.244.175; 18.B.244.240; 18.B.244.244; Prodrugs of 18.D

18.D.228.228; 18.D.228.229; 18.D.228.230; 18.D.228.231; 18.D.228.236; 18.D.228.237; 18.D.228.238; 18.D.228.239; 18.D.228.154; 18.D.228.157; 18.D.228.166; 18.D.228.169; 18.D.228.172; 18.D.228.175; 18.D.228.240; 18.D.228.244; 18.D.229.228; 18.D.229.229; 18.D.229.230; 18.D.229.231; 18.D.229.236; 18.D.229.237; 18.D.229.238; 18.D.229.239; 18.D.229.154; 18.D.229.157; 18.D.229.166; 18.D.229.169; 18.D.229.172; 18.D.229.175; 18.D.229.240; 18.D.229.244; 18.D.230.228; 18.D.230.229; 18.D.230.230; 18.D.230.231; 18.D.230.236; 18.D.230.237; 18.D.230.238; 18.D.230.239; 18.D.230.154; 18.D.230.157; 18.D.230.166; 18.D.230.169; 18.D.230.172; 18.D.230.175; 18.D.230.240; 18.D.230.244; 18.D.231.228; 18.D.231.229; 18.D.231.230; 18.D.231.231; 18.D.231.236; 18.D.231.237; 18.D.231.238; 18.D.231.239; 18.D.231.154; 18.D.231.157; 18.D.231.166; 18.D.231.169; 18.D.231.172; 18.D.231.175; 18.D.231.240; 18.D.231.244; 18.D.236.228; 18.D.236.229; 18.D.236.230; 18.D.236.231; 18.D.236.236; 18.D.236.237; 18.D.236.238; 18.D.236.239; 18.D.236.154; 18.D.236.157; 18.D.236.166; 18.D.236.169; 18.D.236.172; 18.D.236.175; 18.D.236.240; 18.D.236.244; 18.D.237.228; 18.D.237.229; 18.D.237.230; 18.D.237.231; 18.D.237.236; 18.D.237.237; 18.D.237.238; 18.D.237.239; 18.D.237.154; 18.D.237.157; 18.D.237.166; 18.D.237.169; 18.D.237.172; 18.D.237.175; 18.D.237.240; 18.D.237.244; 18.D.238.228; 18.D.238.229; 18.D.238.230; 18.D.238.231; 18.D.238.236; 18.D.238.237; 18.P.238.238; 18.D.238.239; 18.D.238.154; 18.D.238.157; 18.D.238.166; 18.D.238.169; 18.D.238.172; 18.D.238.175; 18.D.238.240; 18.D.238.244; 18.D.239.228; 18.D.239.229; 18.D.239.230; 18.D.239.231; 18.D.239.236; 18.D.239.237; 18.D.239.238; 18.D.239.239; 18.D.239.154; 18.D.239.157; 18.D.239.166; 18.D.239.169; 18.D.239.172; 18.D.239.175; 18.D.239.240; 18.D.239.244; 18.D.154.228; 18.D.154.229; 18.D.154.230; 18.D.154.231; 18.D.154.236; 18.D.154.237; 18.D.154.238; 18.D.154.239; 18.D.154.154; 18.D.154.157; 18.D.154.166; 18.D.154.169; 18.D.154.172; 18.D.154.175; 18.D.154.240; 18.D.154.244; 18.D.157.228; 18.D.157.229; 18.D.157.230; 18.D.157.231; 18.D.157.236; 18.D.157.237; 18.D.157.238; 18.D.157.239; 18.D.157.154; 18. ,D.157.157; 18.D.157.166; 18.D.157.169; 18.D.157.172; 18.D.157.175; 18.D.157.240; 18.D.157.244; 18.D.166.228; 18.D.166.229; 18.D.166.230; 18.D.166.231; 18.D.166.236; 18.D.166.237; 18.D.166.238; 18.D.166.239; 18.D.166.154; 18.D.166.157; 18.D.166.166; 18.D.166.169; 18.D.166.172; 18.D.166.175; 18.D.166.240; 18.D.166.244; 18.D.169.228; 18.D.169.229; 18.D.169.230; 18.D.169.231; 18.D.169.236; 18.D.169.237; 18.D.169.238; 18.D.169.239; 18.D.169.154; 18.D.169.157; 18.D.169.166; 18.D.169.169; 18.D.169.172; 18.D.169.175; 18.D.169.240; 18.D.169.244; 18.D.172.228; 18.D.172.229; 18.D.172.230; 18.D.172.231; 18.D.172.236; 18.D.172.237; 18.D.172.238; 18.D.172.239; 18.D.172.154; 18.D.172.157; 18.D.172.166; 18.D.172.169; 18.D.172.172; 18.D.172.175; 18.D.172.240; 18.D.172.244; 18.D.175.228; 18.D.175.229; 18.D.175.230; 18.D.175.231; 18.D.175.236; 18.D.175.237; 18.D.175.238; 18.D.175.239; 18.D.175.154; 18.D.175.157; 18.D.175.166; 18.D.175.169; 18.D.175.172; 18.D.175.175; 18.D.175.240; 18.D.175.244; 18.D.240.228; 18.D.240.229; 18.D.240.230; 18.D.240.231; 18.D.240.236; 18.D.240.237; 18.D.240.238; 18.D.240.239; 18.D.240.154; 18.D.240.157; 18.D.240.166; 18.D.240.169; 18.D.240.172; 18.D.240.175; 18.D.240.240; 18.D.240.244; 18.D.244.228; 18.D.244.229; 18.D.244.230; 18.D.244.231; 18.D.244.236; 18.D.244.237; 18.D.244.238; 18.D.244.239; 18.D.244.154; 18.D.244.157; 18.D.244.166; 18.D.244.169; 18.D.244.172; 18.D.244.175; 18.D.244.240; 18.D.244.244;

Prodrugs of 18.AB

18.AB.228.228; 18.AB.228.229; 18.AB.228.230; 18.AB.228.231; 18.AB.228.236; 18.AB.228.237; 18.AB.228.238; 18.AB.228.239; 18.AB.228.154; 18.AB.228.157; 18.AB.228.166; 18.AB.228.169; 18. AB.228.172; 18. AB.228.175; 18. AB.228.240; 18.AB.228.244; 18.AB.229.228; 18.AB.229.229; 18.AB.229.230; 18.AB.229.231; 18.AB.229.236; 18.AB.229.237; 18.AB.229.238; 18.AB.229.239; 18.AB.229.154; 18.AB.229.157; 18. AB.229.166; 18.AB.229.169; 18. AB.229.172; 18.AB.229.175; 18.AB.229.240; 18.AB.229.244; 18.AB.230.228; 18.AB.230.229; 18.AB.230.230; 18.AB.230.231; 18.AB.230.236; 18.AB.230.237; 18.AB.23Q.238; 18.AB.230.239; 18.AB.230.154; 18.AB.230.157; 18.AB.230.166; 18.AB.230.169; 18.AB.230.172; 18.AB.230.175; 18.AB.230.240; 18. AB.230.244; 18.AB.231.228; 18.AB.231.229; 18.AB.231.230; 18.AB.231.231; 18. AB.231.236; 18.AB.231.237; 18.AB.231.238; 18.AB.231.239; 18.AB.231.154; 18.AB.231.157; 18.AB.231.166; 18.AB.231.169; 18.AB.231.172; 18.AB.231.175; 18.AB.231.240; 18.AB.231.244; 18.AB.236.228; 18.AB.236.229; 18.AB.236.230; 18.AB.236.231; 18.AB.236.236; 18.AB.236.237; 18.AB.236.238; 18.AB.236.239; 18.AB.236.154; 18.AB.236.157; 18.AB.236.166; 18.AB.236.169; 18.AB.236.172; 18.AB.236.175; 18.AB.236.240; 18.AB.236.244; 18.AB.237.228; 18.AB.237.229; 18.AB.237.230; 18.AB.237.231; 18.AB.237.236; 18.AB.237.237; 18.AB.237.238; 18.AB.237.239; 18.AB.237.154; 18.AB.237.157; 18.AB.237.166; 18. AB.237.169; 18.AB.237.172; 18.AB.237.175; 18.AB.237.240; 18.AB.237.244; 18.AB.238.228; 18.AB.238.229; 18.AB.238.230; 18.AB.238.231; 18.AB.238.236; 18.AB.238.237; 18.AB.238.238; 18.AB.238.239; 18.AB.238.154; 18.AB.238.157; 18.AB.238.166; 18.AB.238.169; 18.AB.238.172; 18.AB.238.175; 18.AB.238.240; 18.AB.238.244; 18. AB .239.228; 18.AB.239.229; 18.AB.239.230; 18.AB.239.231; 18.AB.239.236; 18.AB.239.237; 18.AB.239.238; 18. AB.239.239; 18.AB.239.154; 18.AB.239.157; 18.AB.239.166; 18.AB.239.169; 18.AB.239.172; 18.AB.239.175; 18.AB.239.240; 18.AB.239.244; 18.AB.154.228; 18.AB.154.229; 18.AB.154.230; 18.AB.154.231; 18.AB.154.236; 18.AB.154.237; 18.AB.154.238; 18.AB.154.239; 18.AB.154.154; 18.AB.154.157; 18.AB.154.166; 18.AB.154.169; 18.AB.154.172; 18.AB.154.175; 18.AB.154.240; 18.AB.154.244; 18.AB.157.228; 18.AB.157.229; 18.AB.157.230; 18.AB.157.231; 18.AB.157.236; 18.AB.157.237; 18.AB.157.238; 18.AB.157.239; 18.AB.157.154; 18.AB.157.157; 18.AB.157.166; 18.AB.157.169; 18.AB.157.172; 18.AB.157.175; 18.AB.157.240; 18.AB.157.244; 18.AB.166.228; 18.AB.166.229; 18.AB.166.230; 18.AB.166.231; 18.AB.166.236; 18.AB.166.237; 18.AB.166.238; 18.AB.166.239; 18.AB.166.154; 18.AB.166.157; 18.AB.166.166; 18.AB.166.169; 18.AB.166.172; 18.AB.166.175; 18.AB.166.240; 18.AB.166.244; 18.AB.169.228; 18.AB.169.229; 18.AB.169.230; 18.AB.169.231; 18.AB.169.236; 18.AB.169.237; 18.AB.169.238; 18.AB.169.239; 18.AB.169.154; 18.AB.169.157; 18.AB.169.166; 18.AB.169.169; 18.AB.169.172; 18.AB.169.175; 18.AB.169.240; 18. AB.169.244; 18.AB.172.228; 18.AB.172.229; 18.AB.172.230; 18.AB.172.231; 18.AB.172.236; 18.AB.172.237; 18.AB.172.238; 18.AB.172.239; 18.AB.172.154; 18.AB.172.157; 18.AB.172.166; 18.AB.172.169; 18.AB.172.172; 18.AB.172.175; 18.AB.172.240; 18.AB.172.244; 18.AB.175.228; 18.AB.175.229; 18.AB.175.230; 18.AB.175.231; 18.AB.175.236; 18.AB.175.237; 18. AB.175.238; 18.AB.175.239; 18.AB.175.154; 18.AB.175.157; 18.AB.175.166; 18.AB.175.169; 18.AB.175.172; 18.AB.175.175; 18.AB.175.240; 18.AB.175.244; 18.AB.240.228; 18.AB.240.229; 18.AB.240.230; 18.AB.240.231; 18.AB.240.236; 18.AB.240.237; 18.AB.240.238; 18.AB.240.239; 18.AB.240.154; 18.AB-240.157; 18.AB.240.166; 18.AB.240.169; 18.AB.240.172; 18. AB.240.175; 18.AB.240.240; 18. AB.240.244; 18.AB.244.228; 18.AB.244.229; 18.AB.244.230; 18.AB.244.231; 18.AB.244.236; 18.AB.244.237; 18.AB.244.238; 18.AB.244.239; 18.AB.244.154; 18.AB.244.157; 18.AB.244.166; 18.AB.244.169; 18.AB.244.172; 18.AB.244.175; 18.AB.244.240; 18.AB.244.244;

Prodrugs of 18.BI

18.BI.228.228; 18.BI.228.229; 18.BI.228.230; 18.BI.228.231; 18.BI.228.236; 18.BI.228.237; 18.BI.228.238; 18.BI.228.239; 18.BI.228.154; 18.BI.228.157; 18.BI.228.166; 18.BI.228.169; 18.BI.228.172; 18.BI.228.175; 18.BI.228.240; 18.BI.228.244; 18.BI.229.228; 18-BI.229.229; 18.BI.229.230; 18.BI.229.231; 18.BI.229.236; 18.BI.229.237; 18.BI.229.238; 18.BI.229.239; 18.BI.229.154; 18.BI.229.157; 18.BI.229.166; 18.BI.229.169; 18.BI.229.172; 18.BI.229.175; 18.BI.229.240; 18.BI.229.244; 18.BI.230.228; 18.BI.230-229; 18.BI.230.230; 18.BI.230.231; 18.BI.230.236; 18.BI.230.237; 18.BI.230.238; 18.BI.230.239; 18.BI.230.154; 18.BI.23Q.157; 18.BI.230.166; 18.BI.230.169; 18.BI.230.172; 18.BI.230.175; 18.BI.230.240; 18.BI.230.244; 18.BI.231.228; 18.BI.231.229; 18.BI.231.230; 18.BI.231.231; 18.BL231.236; 18.BI.231.237; 18.BI.231.238; 18.BI.231.239; 18.BI.231.154; 18.BI.231.157; 18.BI.231.166; 18.BI.231.169; 18.BI.231.172; 18.BI.231.175; 18.BI.231.240; 18.BI.231.244; 18.BI.236.228; 18.BI.236.229; 18.BI.236.230; 18.BI.236.231; 18.BI.236.236; 18.BI.236.237; 18.BI.236.238; 18.BI.236.239; 18.BI.236.154; 18.BI.236.157; 18.BI.236.166; 18.BI.236.169; 18.BI.236.172; 18.BI.236.175; 18.BI.236.240; 18.BI.236.244; 18.BI.237.228; 18.BI.237.229; 18.BI.237.230; 18.BI.237.231; 18.BI.237.236; 18.BI.237.237; 18.BI.237.238; 18.BI.237.239; 18.BI.237.154; 18.BI.237.157; 18.BI.237.166; 18.BI.237.169; 18.BI.237.172; 18.BI.237.175; 18.BI.237.240; 18.BI.237.244; 18.BI.238.228; 18.BI.238.229; 18.BI.238.230; 18.BI.238.231; 18.BI.238.236; 18.BI.238.237; 18.BI.238.238; 18.BI.238.239; 18.BI.238.154; 18.BI.238.157; 18.BI.238.166; 18.BI.238.169; 18.BI.238.172; 18.BI.238.175; 18.BI.238.240; 18.BI.238.244; 18.BL239.228; 18.BI.239.229; 18.BI.239.230; 18.BI.239.231; 18.BI.239.236; 18.BI.239.237; 18.BI.239.238; 18.BI.239.239; 18.BI.239.154; 18.BI.239.157; 18.BI.239.166; 18.BI.239.169; 18.BI.239.172; 18.BI.239.175; 18.BI.239.240; 18.BI.239.244; 18.BI.154.228; 18.BI.154.229; 18.BI.154.230; 18.BI.154.231; 18.BI.154.236; 18.BL154.237; 18.BI.154.238; 18.BI.154.239; 18.BI.154.154; 18.BI.154.157; 18.BI.154.166; 18.BI.154.169; 18.BI.154.172; 18.BI.154.175; 18.BI.154.240; 18.BI.154.244; 18.BI.157.228; 18.BI.157.229; 18.BL157.230; 18.BL157.231; 18.BI.157.236; 18.BI.157.237; 18.BI.157.238; 18.BI.157.239; 18.BI.157.154; 18.BI.157.157; 18.BL157.166; 18.BI.157.169; 18.BI.157.172; 18.BI.157.175; 18.BI.157.240; 18.BI.157.244; 18.BI.166.228; 18.BI.166.229; 18.BI.166.230; 18.BI.166.231; 18.BI.166.236; 18.BI.166.237; 18.BI.166.238; 18.BI.166.239; 18.BI.166.154; 18.BL166.157; 18.BI.166.166; 18.BI.166.169; 18.BI.166.172; 18.BI.166.175; 18.BI.166.240; 18.BI.166.244; 18.BI.169.228; 18.BI.169.229; 18.BI.169.230; 18.BI.169.231; 18.BI.169.236; 18.BI.169.237; 18.BI.169.238; 18.BI.169.239; 18.BI.169.154; 18.BI.169.157; 18.BI.169.166; 1831.169.169; 18.BI.169.172; 18.BI.169.175; 18.BI.169.240; 18.BI.169.244; 18.BI.172.228; 18.BI.172.229; 18.BI.172.230; 18.BI.172.231; 18.BI.172.236; 18.BI.172.237; 18.BI.172.238; 18.BI.172.239; 18.BI.172.154; 18.BI.172.157; 18.BL172.166; 18.BI.172.169; 18.BI.172.172; 18.BL172.175; 18.BI.172.240; 18.BI.172.244; 18.BI.175.228; 18.BI.175.229; 18.BI.175.230; 18.BI.175.231; 18. BI.175.236; 18.BI.175.237; 18.BI.175.238; 18.BI.175.239; 18.BI.175.154; 18.BI.175.157; 18.BI.175.166; 18.BI.175.169; 18.BI.175.172; 18.BI.175.175; 18.BI.175.240; 18.BI.175.244; 18.BI.240.228; 18.BI.240.229; 18.BI.240.230; 18.BI.240.231; 18.BI.240.236; 18.BI.240.237; 18.BI.240.238; 18.BI.240.239; 18.BI.240.154; 18.BI.240.157; 18.BI.240.166; 18.BI.240.169; 18.BI.240.172; 18.BI.240.175; 18.BI.240.240; 18.BI.240.244; 18.BI.244.228; 18.BI.244.229; 18.BI.244.230; 18.BI.244.231; 18.BI.244.236; 18.BI.244.237; 18.BI.244.238; 18.BI.244.239; 18.BI.244.154; 18.BI.244.157; 18.BI.244.166; 18.BI.244.169; 18.BI.244.172; 18.BI.244.175; 18.BI.244.240; 18.BI.244.244;

Prodrugs of 18.1

18.1.228.228; 18.1.228.229; 18.1.228.230; 18.1.228.231; 18.1.228.236; 18.1.228.237; 18.1.228.238; 18.1.228.239; 18.1.228.154; 18.1.228.157; 18.1.228.166; 18.1.228.169; 18.1.228.172; 18.1.228.175; 18.1.228.240; 18.1.228.244; 18.1.229.228; 18.1.229.229; 18.1.229.230; 18.1.229.231; 18.1.229.236; 18.1.229.237; 18.1.229.238; 18.1.229.239; 18.1.229.154; 18.1.229.157; 18.1.229.166; 18.1.229.169; 18..1.229.172; 18.1.229.175; 18.1.229.240; 18.1.229.244; 18.1.230.228; 18.1.230.229; 18.1.230.230; 18.1.230.231; 18.1.230.236; 18.1.230.237; 18.1.230.238; 18.1.230.239; 18.1.230.154; 18.1.230.157; 18.1.230.166; 18.1.230.169; 18.1.230.172; 18.1.230.175; 18.1.230.240; 18.1.230.244; 18.1.231.228; 18.1.231.229; 18.1.231.230; 18.1.231.231; 18.1.231.236; 18.1.231.237; 18.1.231.238; 18.1.231.239; 18.1.231.154; 18.1.231.157; 18.1.231.166; 18.1.231.169; 18.1.231.172; 18.1.231.175; 18.1.231.240; 18.1.231.244; 18.1.236.228; 18.1.236.229; 18.1.236.230; 18.1.236.231; 18.1.236.236; 18.1.236.237; 18.1.236.238; 18.1.236.239; 18.1.236.154; 18.1.236.157; 18.1.236.166; 18.1.236.169; 18.1.236.172; 18.1.236.175; 18.1.236.240; 18.1.236.244; 18.1.237.228; 18.1.237.229; 18.1.237.230; 18.1.237.231; ^■ 18.1.237.236; 18.1.237.237; 18.1.237.238; 18.1.237.239; 18.1.237.154; 18.1.237.157; 18.1.237.166; 18.1.237.169; 18.1.237.172; 18.1.237.175; 18.1.237.240; 18.1.237.244; 18.1.238.228; 18.1.238.229; 18.1.238.230; 18.1.238.231; 18.1.238.236; 18.1.238.237; 18.1.238.238; 18.1.238.239; 18.1.238.154; 18.1.238.157; 18.1.238.166; 18.1.238.169; 18.1.238.172; 18.1.238.175; 18.1.238.240; 18.1.238.244; 18.1.239.228; 18.1.239.229; 18.1.239.230; 18.1.239.231; 18.1.239.236; 18.1.239.237; 18.1.239.238; 18.1.239.239; 18.1.239.154; 18.1.239.157; 18.1.239.166; 18.1.239.169; 18.1.239.172; 18.1.239.175; 18.1.239.240; 18.1.239.244; 18.1.154.228; 18.1.154.229; 18.1.154.230; 18.1.154.231; 18.1.154.236; 18.1.154.237; 18.1.154.238; 18.1.154.239; 18.1.154.154; 18.1.154.157; 18.1.154.166; 18.1.154.169; 18.1.154.172; 18.1.154.175; 18.1.154.240; 18.1.154.244; 18.1.157.228; 18.1.157.229; 18.1.157.230; 18.1.157.231; 18.1.157.236; 18.1.157.237; 18.1.157.238; 18.1.157.239; 18.1.157.154; 18.1.157.157; 18.1.157.166; 18.1.157.169; 18.1.157.172; 18.1.157.175; 18.1.157.240; 18.1.157.244; 18.1.166.228; 18.1.166.229; 18.1.166.230; 18.1.166.231; 18.1.166.236; 18.1.166.237; 18.1.166.238; 18.1.166.239; 18.1.166.154; 18.1.166.157; 18.1.166.166; 18.1.166.169; 18.1.166.172; 18.1.166.175; 18.1.166.240; 18.1.166.244; 18.1.169.228; 18.1.169.229; 18.1.169.230; 18.1.169.231; 18.1.169.236; 18.1.169.237; 18.1.169.238; 18.1.169.239; 18.1.169.154; 18.1.169.157; 18.1.169.166; 18.1.169.169; 18.1.169.172; 18.1.169.175; 18.1.169.240; 18.1.169.244; 18.1.172.228; 18.1.172.229; 18.1.172.230; 18.1.172.231; 18.1.172.236; 18.1.172.237; 18.1.172.238; 18.1.172.239; 18.1.172.154; 18.1.172.157; 18.1.172.166; 18.1.172.169; 18.1.172.172; 18.1.172.175; 18.1.172.240; 18.1.172.244; 18.1.175.228; 18.1.175.229; 18.1.175.230; 18.1.175.231; 18.1.175.236; 18.1.175.237; 18.1.175.238; 18.1.175.239; 18.1.175.154; 18.1.175.157; 18.1.175.166; 18.1.175.169; 18.1.175.172; 18.1.175.175; 18.1.175.240; 18.1.175.244; 18.1.240.228; 18.1.240.229; 18.1.240.230; 18.1.240.231; 18.1.240.236; 18.1.240.237; 18.1.240.238; 18.1.240.239; 18.1.240.154; 18.1.240.157; 18.1.240.166; 18.1.240.169; 18.1.240.172; 18.1.240.175; 18.1.240.240; 18.1.240.244; 18.1.244.228; 18.1.244.229; 18.1.244.230; 18.1.244.231; 18.1.244.236; 18.1.244.237; 18.1.244.238; 18.1.244.239; 18.1.244.154; 18.1.244.157; 18.1.244.166; 18.1.244.169; 18.1.244.172; 18.1.244.175; 18.1.244.240; 18.1.244.244;

Prodrugs of 18.T

18.J.228.228; 18.J.228.229; 18.J.228.230; 18.J.228.231; 18.J.228.236; 18.J.228.237; 18.J.228.238; 18.J.228.239; 18.J.228.154; 18J.228.157; 18J.228.166; 18J.228.169; 18.J.228.172; 18J.228.175; 18J.228.240; 18J.228.244; 18J.229.228; 18J.229.229; 18.J.229.230; 18J.229.231; 18J.229.236; 18J.229.237; 18.J.229.238; 18J.229.239; 18.J.229.154; 18J.229.157; 18J.229.166; 18J.229.169; 18.J.229.172; 18J.229.175; 18J.229.240; 18J.229.244; 18J.230.228; 18J.230.229; 18J.230.230; 18J.230.231; 18J.230.236; 18J.230.237; 18J.230.238; 18J.230.239; 18J.230.154; 18J.230.157; 18J.230.166; 18J.230.169; 18J.230.172; 18J.230.175; 18J.230.240; 18J.230.244; 18J.231.228; 18J.231.229; 18J.231.230; 18J.231.231; 18J.231.236; 18J.231.237; 18.J.231.238; 18.J.231.239; 18J.231.154; 18J.231.157; 18J.231.166; 18J.231.169; 18.J.231.172; 18J.231.175; 18J.231.240; 18J.231.244; 18J.236.228; 18J.236.229; 18J.236.230; 18J.236.231; 18J.236.236; 18J.236.237; 18J.236.238; 18J.236.239; 18J.236.154; 18J.236.157; 18J.236.166; 18J.236.169; 18J.236.172; 18J.236.175; 18J.236.240; 18J.236.244; 18J.237.228; 18J.237.229; 18J.237.230; 18J.237.231; 18J.237.236; 18J.237.237; 18J.237.238; 18J.237.239; 18J.237.154; 18.J.237.157; 18J.237.166; 18J.237.169; 18J.237.172; 18J.237.175; 18.J.237.240; 18.J.237.244; 18J.238.228; 18J.238.229; 18J.238.230; 18J.238.231; 18J.238.236; 18J.238.237; 18J.238.238; 18J.238.239; 18J.238.154; 18J.238.157; 18J.238.166; 18J.238.169; 18J.238.172; 18J.238.175; 18J.238.240; 18J.238.244; 18J.239.228; 18J.239.229; 18J.239.230; 18J.239.231; 18J.239.236; 18J.239.237; 18J.239.238; 18J.239.239; 18J.239.154; 18J.239.157; 18J.239.166; 18J.239.169; 18J.239.172; 18J.239.175; 18J.239.240; 18.J.239.244; 18J.154.228; 18J.154.229; 18J.154.230; 18.J.154.231; 18.J.154.236; 18.J.154.237; 18.J.154.238; 18.J.154.239; 18.J.154.154; 18.J.154.157; 18.J.154.166; 18.J.154.169; 18.J.154.172; 18.J.154.175; 18.J.154.240; 18.J.154.244; 18.J.157.228; 18.J.157.229; 18.J.157.230; 18J.157.231; 18J.157.236; 18J.157.237; 18J.157.238; 18.J.157.239; 18.J.157.154; 18J.157.157; 18J.157.166; 18J.157.169; 18J.157.172; 18J.157.175; 18J.157.240; 18J.157.244; 18J.166.228; 18 J.166.229; 18J.166.230; 18J.166.231; 18J.166.236; 18J.166.237; 18J.166.238; 18J.166.239; 18J.166.154; 18J.166.157; 18J.166.166; 18J.166.169; 18J.166.172; 18J.166.175; 18J.166.240; 18.J.166.244; 18.J.169.228; 18J.169.229; 18.J.169.230; 18J.169.231; 18J.169.236; 18.J.169.237; 18J.169.238; 18J.169.239; 18J.169.154; 18J.169.157; 18J.169.166; 18J.169.169; 18.J..169.172; 18J.169.175; 18J.169.240; 18J.169.244; 18J.172.228; 18J.172.229; 18J.172.230; 18J.172.231; 18J.172.236; 18 J.172.237; 18J.172.238; 18J.172.239; 18J.172.154; 18J.172.157; 18J.172.166; 18J.172.169; 18.J.172.172; 18.J.172.175; 18.J.172.240; 18J.172.244; 18J.175.228; 18.J.175.229; 18J.175.230; 18J.175.231; 18J.175.236; 18J.175.237; 18J.175.238; 18.J.175.239; 18J.175.154; 18J.175.157; 18J.175.166; 18J.175.169; 18.J.175.172; 18J.175.175; 18J.175.240; 18.J.175.244; 18.J.240.228; 18J.240.229; 18J.240.230; 18J.240.231; 18J.240.236; 18J.240.237; 18.J.240.238; 18J.240.239; 18J.240.154; 18 J.240.157; 18J.240.166; 18J.240.169; 18J.240.172; 18J.240.175; 18J.240.240; 18J.240.244; 18J.244.228; 18J.244.229; 18.J.244.230; 18J.244.231; 18J.244.236; 18J.244.237; 18J.244.238; 18J.244.239; 18.J.244.154; 18J.244.157; 18J.244.166; 18J.244.169; 18J.244.172; 18J.244.175; 18.J.244.24Q; 18J.244.244;

Prodrugs of 18.L

18.L.228.228; 18.L.228.229; 18.L.228.230; 18.L.228.231; 18.L.228.236; 18.L.228.237; 18.L.228.238; 18.L.228.239; 18.L.228.154; 18.L.228.157; 18.L.228.166; 18.L.228.169; 18.L.228.172; 18.L.228.175; 18.L.228.240; 18.L.228.244; 18.L.229.228; 18.L.229.229; 18.L.229.230; 18.L.229.231; 18X.229.236; 18.L.229.237; 18.L.229.238; 18.L.229.239; 18.L.229.154; 18.L.229.157; 18.L.229.166; 18.L.229.169; 18.L.229.172; 18.L.229.175; 18.L.229.240; 18.L.229.244; 18.L.230.228; 18.L.230.229; 18.L.230.230; 18.L.230.231; 18.L.230.236; 18.L.230.237; 18.L.230.238; 18.L.230.239; 18.L.230.154; 18.L.230.157; 18.L.230.166; 18.L.230.169; 18.L.230.172; 18.L.230.175; 18.L.230.240; 18.L.230.244; 18.L.231.228; 18.L.231.229; 18.L.231.230; 18.L.231.231; 18.L.231.236; 18.L.231.237; 18.L.231.238; 18.L.231.239; 18.L.231.154; 18.L.231.157; 18X.231.166; 18.L.231.169; 18X.231.172; 18X.231.175; 18X.231.240; 18X.231.244; 18X.236.228; 18X.236.229; 18X.236.230; 18X.236.231; 18X.236.236; 18X.236.237; 18X.236.238; 18X.236.239; 18X.236.154; 18X.236.157; 18X.236.166; 18X.236.169; 18X.236.172; 18X.236.175; 18X.236.240; 18X.236.244; 18X.237.228; 18X.237.229; 18X.237.230; 18X.237.231; 18X.237.236; 18.L.237.237; 18X.237.238; 18X.237.239; 18X.237.154; 18X.237.157; 18X.237.166; 18X.237.169; 18X.237.172; 18X.237.175; 18X.237.240; 18X.237.244; 18X.238.228; 18X.238.229; 18X.238.230; 18X.238.231; 18.L.238.236; 18X.238.237; 18X.238.238; 18X.238.239; 18X.238.154; 18X.238.157; 18X.238.166; 18.L.238.169; 18X.238.172; 18X.238.175; 18X.238.240; 18.L.238.244; 18X.239.228; 18X.239.229; 18X.239.230; 18X.239.231; 18X.239.236; 18X.239.237; 18X.239.238; 18X.239.239; 18X.239.154; 18X.239.157; 18X.239.166; 18X.239.169; 18X.239.172; 18X.239.175; 18X.239.240; 18X.239.244; 18X.154.228; 18X.154.229; 18X.154.230; 18X.154.231; 18X.154.236; 18.L.154.237; 18X.154.238; 18X.154.239; 18X.154.154; 18.L.154.157; 18.L.154.166; 18.L.154.169; 18.L.154.172; 18.L.154.175; 18.L.154.240; 18.L.154.244; 18.L.157.228; 18.L.157.229; 18.L.157.230; 18.L.157.231; 18.L.157.236; 18.L.157.237; 18.L.157.238; 18.L.157.239; 18.L.157.154; 18.L.157.157; 18.L.157.166; 18.L.157.169; 18.L.157.172; 18.L.157.175; 18.L.157.240; 18.L.157.244; 18.L.166.228; 18.L.166.229; 18.L.166.230; 18.L.166.231; 18.L.166.236; 18.L.166.237; 18.L.166.238; 18.L.166.239; 18.L.166.154; 18.L.166.157; 18.L.166.166; 18.L.166.169; 18.L.166.172; 18.L.166.175; 18.L.166.240; 18.L.166.244; 18.L.169.228; 18.L.169.229; 18.L.169.230; 18.L.169.231; 18.L.169.236; 18.L.169.237; 18.L.169.238; 18.L.169.239; 18.L.169.154; 18.L.169.157; 18.L.169.166; 18.L.169.169; 18.L.169.172; 18.L.169.175; 18.L.169.240; 18.L.169.244; 18.L.172.228; 18.L.172.229; 18.L.172.230; 18.L.172.231; 18.L.172.236; 18.L.172.237; 18.L.172.238; 18.L.172.239; 18.L.172.154; 18.L.172.157; 18.L.172.166; 18.L.172.169; 18.L.172.172; 18.L.172.175; 18.L.172.240; 18.L.172.244; 18.L.175.228; 18.L.175.229; 18.L.175.230; 18.L.175.231; 18.L.175.236; 18.L.175.237; 18.L.175.238; 18.L.175.239; 18.L.175.154; 18.L.175.157; 18.L.175.166; 18.L.175.169; 18.L.175.172; 18.L.175.175; 18.L.175.24Q; 18.L.175.244; 18.L.240.228; 18.L.240.229; 18.L.240.230; 18.L.240.231; 18.L.240.236; 18.L.240.237; 18.L.240.238; 18.L.240.239; 18.L.240.154; 18.L.240.157; 18.L.240.166; 18.L.240.169; 18.L.240.172; 18.L.240.175; 18.L.240.240; 18.L.240.244; 18.L.244.228; 18.L.244.229; 18.L.244.230; 18.L.244.231; 18.L.244.236; 18.L.244.237; 18.L.244.238; 18.L.244.239; 18.L.244.154; 18.L.244.157; 18.L.244.166; 18.L.244.169; 18.L.244.172; 18.L.244.175; 18.L.244.240; 18.L.244.244;

Prodrugs of 18.O

18.O.228.228; 18.O.228.229; 18.O.228.230; 18.O.228.231; 18.O.228.236; 18.O.228.237; 18.O.228.238; 18.O.228.239; 18.0.228.154; 18.O.228.157; 18.O.228.166; 18.O.228.169; 18.O.228.172; 18.O.228.175; 18.O.228.240; 18.O.228.244; 18.O.229.228; 18.O.229.229; 18.O.229.230; 18.O.229.231; 18.O.229.236; 18.O.229.237; 18.O.229.238; 18.O.229.239; 18.O.229.154; 18.O.229.157; 18.O.229.166; 18.O.229.169; 18.O.229.172; 18.O.229.175; 18.O.229.240; 18.O.229.244; 18.O.230.228; 18.O.230.229; 18.O.230.230; 18.O.230.231; 18.O.230.236; 18.O.230.237; 18.O.230.238; 18.O.230.239; 18.O.230.154; 18.O.230.157; 18.O.230.166; 18.O.230.169; 18.O.230.172; 18.O.230.175; 18.O.230.240; 18.O.230.244; 18.O.231.228; 18.O.231.229; 18.O.231.230; 18.O.231.231; 18.O.231.236; 18.O.231.237; 18.O.231.238; 18.O.231.239; 18.O.231.154; 18.O.231.157; 18.O.231.166; 18.O.231.169; 18.O.231.172; 18.O.231.175; 18.O.231.240; 18.O.231.244; 18.O.236.228; 18.O.236.229; 18.O.236.230; 18.O.236.231; 18.O.236.236; 18.O.236.237; 18.O.236.238; 18.O.236.239; 18.O.236.154; 18.O.236.157; 18.O.236.166; 18.O.236.169; 18.O.236.172; 18.O.236.175; 18.O.236.240; 18.O.236.244; 18.O.237.228; 18.O.237.229; 18.O.237.230; 18.O.237.231; 18.O.237.236; 18.O.237.237; 18.O.237.238; 18.O.237.239; 18.O.237.154; 18.O.237.157; 18.O.237.166; 18.O.237.169; 18.O.237.172; 18.O.237.175; 18.O.237.240; 18.O.237.244; 18.O.238.228; 18.O.238.229; 18.O.238.230; 18.O.238.231; 18.O.238.236; 18.O.238.237; 18.O.238.238; 18.O.238.239; 18.O.238.154; 18.O.238.157; 18.O.238.166; 18.O.238.169; 18.O.238.172; 18.O.238.175; 18.O.238.240; 18.O.238.244; 18.O.239.228; 18.O.239.229; 18.O.239.230; 18.O.239.231; 18.O.239.236; 18.O.239.237; 18.O.239.238; 18.O.239.239; 18.O.239.154; 18.O.239.157; 18.O.239.166; 18.O.239.169; 18.O.239.172; 18.O.239.175; 18.O.239.240; 18.O.239.244; 18.O.154.228; 18.O.154.229; 18.O.154.230; 18.O.154.231; 18.O.154.236; 18.O.154.237; 18.O.154.238; 18.O.154.239; 18.O.154.154; 18.O.154.157; 18.O.154.166; 18.O.154.169; 18.O.154.172; 18.O.154.175; 18.O.154.240; 18.O.154.244; 18.O.157.228; 18.O.157.229; 18.O.157.230; 18.O.157.231; 18.O.157.236; 18.O.157.237; 18.O.157.238; 18.O.157.239; 18.O.157.154; 18.O.157.157; 18.O.157.166; 18.O.157.169; 18.O.157.172; 18.O.157.175; 18.O.157.240; 18.O.157.244; 18.O.166.228; 18.O.166.229; 18.O.166.23Q; 18.O.166.231; 18.O.166.236; 18.O.166.237; 18.O.166.238; 18.O.166.239; 18.O.166.154; 18.O.166.157; 18.O.166.166; 18.O.166.169; 18.O.166.172; 18.O.166.175; 18.O.166.240; 18.O.166.244; 18.O.169.228; 18.O.169.229; 18.O.169.230; 18.O.169.231; 18.O.169.236; 18.O.169.237; 18.O.169.238; 18.O.169.239; 18.O.169.154; 18.O.169.157; 18.O.169.166; 18.O.169.169; 18.O.169.172; 18.O.169.175; 18.O.169.240; 18.O.169.244; 18.O.172.228; 18.O.172.229; 18.O.172.230; 18.O.172.231; 18.O.172.236; 18.O.172.237; 18.O.172.238; 18.O.172.239; 18.O.172.154; 18.O.172.157; 18.O.172.166; 18.O.172.169; 18.O.172.172; 18.O.172.175; 18.O.172.240; 18.O.172.244; 18.O.175.228; 18.O.175.229; 18.O.175.230; 18.O.175.231; 18.O.175.236; 18.O.175.237; 18.O.175.238; 18.O.175.239; 18.O.175.154; 18.O.175.157; 18.O.175.166; 18.O.175.169; 18.O.175.172; 18.O.175.175; 18.O.175.240; 18.O.175.244; 18.O.240.228; 18.O.240.229; 18.O.240.230; 18.O.24Q.231; 18.O.240.236; 18.O.24Q.237; 18.O.240.238; 18.O.240.239; 18.O.240.154; 18.O.240.157; 18.O.240.166; 18.O.240.169; 18.O.240.172; 18.O.240.175; 18.O.240.240; 18.O.240.244; 18.O.244.228; 18.O.244.229; 18.O.244.230; 18.O.244.231; 18.O.244.236; 18.O.244.237; 18.O.244.238; 18.O.244.239; 18.O.244.154; 18.O.244.157; 18.O.244.166; 18.O.244.169; 18.O.244.172; 18.O.244.175; 18.O.244.240; 18.O.244.244;

Prodrugs of 18.P

18.P.228.228; 18.P.228.229; 18.P.228.230; 18.P.228.231; 18.P.228.236; 18.P.228.237; 18.P.228.238; 18.P.228.239; 18.P.228.154; 18.P.228.157; 18.P.228.166; 18.P.228.169; 18.P.228.172; 18.P.228.175; 18.P.228.240; 18.P.228.244; 18.P.229.228; 18.P.229.229; 18.P.229.230; 18.P.229.231; 18.P.229.236; 18.P.229.237; 18.P.229.238; 18.P.229.239; 18.P.229.154; 18.P.229.157; 18.P.229.166; 18.P.229.169; 18.P.229.172; 18.P.229.175; 18.P.229.240; 18.P.229.244; 18.P.230.228; 18.P.230.229; 18.P.230.230; 18.P.230.231; 18.P.230.236; 18.P.230.237; 18.P.230.238; 18.P.230.239; 18.P.230.154; 18.P.230.157; 18.P.230.166; 18.P.230.169; 18.P.230.172; 18.P.230.175; 18.P.230.240; 18.P.230.244; 18.P.231.228; 18.P.231.229; 18.P.231.230; 18.P.231.231; 18.P.231.236; 18.P.231.237; 18.P.231.238; 18.P.231.239; 18.P.231.154; 18.P.231.157; 18.P.231.166; 18.P.231.169; 18.P.231.172; 18.P.231.175; 18.P.231.240; 18.P.231.244; 18.P.236.228; 18.P.236.229; 18.P.236.230; 18.P.236.231; 18.P.236.236; 18.P.236.237; 18.P.236.238; 18.P.236.239; 18.P.236.154; 18.P.236.157; 18.P.236.166; 18.P.236.169; 18.P.236.172; 18.P.236.175; 18.P.236.240; 18.P.236.244; 18.P.237.228; 18.P.237.229; 18.P.237.230; 18.P.237.231; 18.P.237.236; 18.P.237.237; 18.P.237.238; 18.P.237.239; 18.P.237.154; 18.P.237.157; 18.P.237.166; 18.P.237.169; 18.P.237.172; 18.P.237.175; 18.P.237.240; 18.P.237.244; 18.P.238.228; 18.P.238.229; 18.P.238.230; 18.P.238.231; 18.P.238.236; 18.P.238.237; 18.P.238.238; 18.P.238.239; 18.P.238.154; 18.P.238.157; 18.P.238.166; 18.P.238.169; 18.P.238.172; 18.P.238.175; 18.P.238.240; 18.P.238.244; 18.P.239.228; 18.P.239.229; 18.P.239.230; 18.P.239.231; 18.P.239.236; 18.P.239.237; 18.P.239.238; 18.P.239.239; 18.P.239.154; 18.P.239.157; 18.P.239.166; 18.P.239.169; 18. F.239.172; 18.P.239.175; 18.P.239.240; 18.P.239.244; 18.P.154.228; 18.P.154.229; 18.P.154.230; 18.P.154.231; 18.P.154.236; 18.P.154.237; 18.P.154.238; 18.P.154.239; 18.P.154.154; 18.P.154.157; 18.P.154.166; 18.P.154.169; 18.P.154.172; 18.P.154.175; 18.P.154.24Q; 18.P.154.244; 18.P.157.228; 18.P.157.229; 18.P.157.230; 18.P.157.231; 18.P.157.236; 18.P.157.237; 18.P.157.238; 18.P.157.239; 18.P.157.154; 18.P.157.157; 18.P.157.166; 18.P.157.169; 18.P.157.172; 18.P.157.175; 18.P.157.240; 18.P.157.244; 18.P.166.228; 18.P.166.229; 18.P.166.230; 18.P.166.231; 18.P.166.236; 18.P.166.237; 18.P.166.238; 18.P.166.239; 18.P.166.154; 18.P.166.157; 18.P.166.166; 18.P.166.169; 18.P.166.172; 18.P.166.175; 18.P.166.240; 18.P.166.244; 18.P.169.228; 18.P.169.229; 18.P.169.230; 18.P.169.231; 18.P.169.236; 18.P.169.237; 18.P.169.238; 18.P.169.239; 18.P.169.154; 18.P.169.157; 18.P.169.166; 18.P.169.169; 18.P.169.172; 18.P.169.175; 18.P.169.240; 18.P.169.244; 18.P.172.228; 18.P.172.229; 18.P.172.230; 18.P.172.231; 18.P.172.236; 18.P.172.237; 18.P.172.238; 18.P.172.239; 18.P.172.154; 18.P.172.157; 18.P.172.166; 18.P.172.169; 18.P.172.172; 18.P.172.175; 18.P.172.240; 18.P.172.244; 18.P.175.228; 18.P.175.229; 18.P.175.230; 18.P.175.231; 18.P.175.236; 18.P.175.237; 18.P.175.238; 18.P.175.239; 18.P.175.154; 18.P.175.157; 18.P.175.166; 18.P.175.169; 18.P.175.172; 18.P.175.175; 18.P.175.240; 18.P.175.244; 18.P.240.228; 18.P.240.229; 18.P.240.230; 18.P.240.231; 18.P.240.236; 18.P.240.237; 18.P.240.238; 18.P.240.239; 18.P.240.154; 18.P.240.157; 18.P.240.166; 18.P.240.169; 18.P.240.172; 18.P.240.175; 18.P.240.240; 18.P.240.244; 18.P.244.228; 18.P.244.229; 18.P.244.230; 18.P.244.231; 18.P.244.236; 18.P.244.237; 18.P.244.238; 18.P.244.239; 18.P.244.154; 18.P.244.157; 18.P.244.166; 18.P.244.169; 18.P.244.172; 18.P.244.175; 18.P.244.240; 18.P.244.244;

Prodrugs of 18.U

18.U.228.228; 18.U.228.229; 18.U.228.230; 18.U.228.231; 18.U.228.236; 18.U.228.237; 18.U.228.238; 18.U.228.239; 18.U.228.154; 18.U.228.157; 18.U.228.166; 18.U.228.169; 18.U.228.172; 18.U.228.175; 18.U.228.240; 18.U.228.244; 18.U.229.228; 18.U.229.229; 18.U.229.230; 18.U.229.231; 18.U.229.236; 18.U.229.237; 18.U.229.238; 18.U.229.239; 18.U.229.154; 18.U.229.157; 18.U.229.166; 18.U.229.169; 18.U.229.172; 18.U.229.175; 18.U.229.240; 18.U.229.244; 18.U.230.228; 18.U.230.229; 18.U.230.230; 18.U.230.231; 18.U.230.236; 18.U.230.237; 18.U.230.238; 18.U.230.239; 18.U.230.154; 18.U.230.157; 18.U.230.166; 18.U.230.169; 18.U.230.172; 18.U.230.175; 18.U.230.240; 18.U.230.244; 18.U.231.228; 18.U.231.229; 18.U.231.230; 18.U.231.231; 18.U.231.236; 18.U.231.237; 18.U.231.238; 18.U.231.239; 18.U.231.154; 18.U.231.157; 18.U.231.166; 18.U.231.169; 18.U.231.172; 18.U.231.175; 18.U.231.240; 18.U.231.244; 18.U.236.228; 18.U.236.229; 18.U.236.230; 18.U.236.231; 18.U.236.236; 18.U.236.237; 18.U.236.238; 18.U.236.239; 18.U.236.154; 18.U.236.157; 18.U.236.166; 18.U.236.169; 18.U.236.172; 18.U.236.175; 18.U.236.240; 18.U.236.244; 18.U.237.228; 18.U.237.229; 18.U.237.230; 18.U.237.231; 18.U.237.236; 18.U.237.237; 18.U.237.238; 18.U.237.239; 18.U.237.154; 18.U.237.157; 18.U.237.166; 18.U.237.169; 18.U.237.172; 18.U.237.175; 18.U.237.240; 18.U.237.244; 18.U.238.228; 18.U.238.229; 18.U.238.230; 18.U.238.231; 18.U.238.236; 18.U.238.237; 18.U.238.238; 18.U.238.239; 18.U.238.154; 18.U.238.157; 18.U.238.166; 18.U.238.169; 18.U.238.172; 18.U.238.175; 18.U.238.240; 18.U.238.244; 18.U.239.228; 18.U.239.229; 18.U.239.230; 18.U.239.231; 18.U.239.236; 18.U.239.237; 18.U.239.238; 18.U.239.239; 18.U.239.154; 18.U.239.157; 18.U.239.166; 18.U.239.169; 18.U.239.172; 18.U.239.175; 18.U.239.240; 18.U.239.244; 18.U.154.228; 18.U.154.229; 18.U.154.230; 18.U.154.231; 18.U154.236; 18.U.154.237; 18.U.154.238; 18.U.154.239; 18.U.154.154; 18.U.154.157; 18.U.154.166; 18.U.154.169; 18.U.154.172; 18.U.154.175; 18.U.154.240; 18.U.154.244; 18.U.157.228; 18.U.157.229; 18.U.157.230; 18.U.157.231; 18.U.157.236; 18.U.157.237; 18.U.157.238; 18.U.157.239; 18.U.157.154; 18.U.157.157; 18.U.157.166; 18.U.157.169; 18.U.157.172; 18.U.157.175; 18.U.157.240; 18.U.157.244; 18.U.166.228; 18.U.166.229; 18.U.166.230; 18.U.166.231; 18.U.166.236; 18.U.166.237; 18.U.166.238; 18.U.166.239; 18.U.166.154; 18.U.166.157; 18.U.166.166; 18.U.166.169; 18.U.166.172; 18.U.166.175; 18.U.166.240; 18.U.166.244; 18.U.169.228; 18.U.169.229; 18.U.169.230; 18.U.169.231; 18.U.169.236; 18.U.169.237; 18.U.169.238; 18.U.169.239; 18.U.169.154; 18.U.169.157; 18.U.169.166; 18.U.169.169; 18.U.169.172; 18.U.169.175; 18.U.169.240; 18.U.169.244; 18.U.172.228; 18..U 172.229; 18.U.172.230; 18.U.172.231; 18.U.172.236; 18.U.172.237; 18.U.172.238; 18.U.172.239; 18.U.172.154; 18.U.172.157; 18.U.172.166; 18.U.172.169; 18.U.172.172; 18.U.172175; 18.U172.240; 18.U172.244; 18.U175.228; 18.U175.229; 18.U175.230; 18.U175.231; 18.U175.236; 18.U175.237; 18.U175.238; 18.U175.239; 18.U175154; 18.U175157; 18.U175166; 18.U175169; 18.U175172; 18.U175175; 18.U175.240; 18.U175.244; 18.U.240.228; 18.U.240.229; 18.U.240.230; 18.U.240.231; 18.U.240.236; 18.U.240.237; 18.U.240.238; 18.U.240.239; 18.U.240.154; 18.U.240.157; 18.U.240166; 18.U.240169; 18.U.240.172; 18.U.240.175; 18.U.240.240; 18.U.240.244; 18.U.244.228; 18.U.244.229; 18.U.244.230; 18.U.244.231; 18.U.244.236; 18.U.244.237; 18.U.244.238; 18.U.244.239; 18.U.244154; 18.U.244157; 18.U.244166; 18.U.244.169; 18.U.244.172; 18.U.244.175; 18.U.244.240; 18.U.244.244;

Prodrugs of 18.CD

18.CD.228.228; 18.CD.228.229; 18.CD.228.230; 18.CD.228.231; 18.CD.228.236; 18.CD.228.237; 18.CD.228.238; 18.CD.228.239; 18.CD.228.154; 18.CD.228.157; 18.CD.228.166; 18.CD.228169; 18.CD.228.172; 18.CD.228175; 18.CD.228.240; 18.CD.228.244; 18.CD.229.228; 18.CD.229.229; 18.CD.229.230; 18.CD.229.231; 18.CD.229.236; 18.CD.229.237; 18.CD.229.238; 18.CD.229.239; 18.CD.229154; 18.CD.229.157; 18.CD.229166; 18.CD.229169; 18.CD.229.172; 18.CD.229.175; 18.CD.229.240; 18.CD.229.244; 18.CD.230.228; 18.CD.230.229; 18.CD.230.230; 18.CD.230.231; 18.CD.230.236; 18.CD.230.237; 18.CD.230.238; 18.CD.230.239; 18.CD.230154; 18.CD.230.157; 18.CD.230166; 18.CD.230.169; 18.CD.230.172; 18.CD.230.175; 18.CD.230.240; 18.CD.230-244; 18.CD.231.228; 18.CD.231.229; 18.CD.231.230; 18.CD.231.231; 18.CD.231.236; 18.CD.231.237; 18.CD.231.238; 18.CD.231.239; 18.CD.231.154; 18.CD.231.157; 18.CD.231.166; 18.CD.231.169; 18.CD.231.172; 18.CD.231.175; 18.CD.231.240; 18.CD.231.244; 18.CD.236.228; 18.CD.236.229; 18.CD.236.230; 18.CD.236.231; 18.CD.236.236; 18.CD.236.237; 18.CD.236.238; 18.CD.236.239; 18.CD.236.154; 18.CD.236.157; 18.CD.236.166; 18.CD.236.169; 18.CD.236.172; 18.CD.236.175; 18.CD.236.240; 18.CD.236.244; 18.CD.237.228; 18.CD.237.229; 18.CD.237.230; 18.CD.237.231; 18.CD.237.236; 18.CD.237.237; 18.CD.237.238; 18.CD.237.239; 18.CD.237.154; 18.CD.237.157; 18.CD.237.166; 18.CD.237.169; 18.CD.237.172; 18.CP.237.175; 18.CD.237.240; 18.CD.237.244; 18.CD.238.228; 18.CD.238.229; 18.CD.238.230; 18.CD.238.231; 18.CD.238.236; 18.CD.238.237; 18.CD.238.238; 18.CD.238.239; 18.CD.238.154; 18.CP.238.157; 18.CD.238.166; 18.CD.238.169; 18.CD.238.172; 18.CD.238.175; 18.CD.238.240; 18.CD.238.244; 18.CD.239.228; 18.CD.239.229; 18.CD.239.230; 18.CD.239.231; 18.CD.239.236; 18.CD.239.237; 18.CD.239.238; 18.CD.239.239; 18.CD.239.154; 18.CD.239.157; 18.CD.239.166; 18.CD.239.169; 18.CD.239.172; 18.CD.239.175; 18.CD.239.240; 18.CD.239.244; 18.CD.154.228; 18.CD.154.229; 18.CD.154.230; 18.CD.154.231; 18.CD.154.236; 18.CD.154.237; 18.CD.154.238; 18.CD.154.239; 18.CD.154.154; 18.CD.154.157; 18.CP.154.166; 18.CD.154.169; 18.CD.154.172; 18.CD.154.175; 18.CD.154.240; 18.CD.154.244; 18.CD.157.228; 18.CD.157.229; 18.CD.157.230; 18.CD.157.231; 18.CD.157.236; 18.CD.157.237; 18.CD.157.238; 18.CD.157.239; 18.CD.157.154; 18.CD.157.157; 18.CD.157.166; 18.CD.157.169; 18.CD.157.172; 18.CP.157.175; 18.CP.157.240; 18.CP.157.244; 18.CP.166.228; 18.CP.166.229; 18.CP.166.230; 18.CP.166.231; 18.CP.166.236; 18.CP.166.237; 18.CP.166.238; 18.CP.166.239; 18.CP.166.154; 18.CP.166.157; 18.CP.166.166; 18.CP.166.169; 18.CP.166.172; 18.CP.166.175; 18.CP.166.240; 18.CP.166.244; 18.CP.169.228; 18.CP.169.229; 18.CP.169.230; 18.CP.169.231; 18.CP.169.236; 18.CP.169.237; 18.CP.169.238; 18.CP.169.239; 18.CP.169.154; 18.CP.169.157; 18.CP.169.166; 18.CP.169.169; 18.CP.169.172; 18.CP.169.175; 18.CP.169.240; 18.CP.169.244; 18.CP.172.228; 18. CP '.172.229; 18.CP.172.230; 18.CP.172.231; 18.CP.172.236; 18.CP.172.237; 18.CP.172.238; 18.CP.172.239; 18.CP.172.154; 18.CP.172.157; 18.CP.172.166; 18.CP.172.169; 18.CP.172.172; 18.CP.172.175; 18.CP.172.240; 18.CP.172.244; 18.CP.175.228; 18.CP.175.229; 18.CP.175.230; 18.CP.175.231; 18.CP.175.236; 18.CP.175.237; 18.CP.175.238; 18.CP.175.239; 18.CP.175.154; 18.CP.175.157; 18.CP.175.166; 18.CP.175.169; 18.CP.175.172; 18.CP.175.175; 18.CP.175.240; 18.CP.175.244; 18.CP.240.228; 18.CP.240.229; 18.CP.240.230; 18.CP.240.231; 18.CP.240.236; 18.CP.240.237; 18.CP.240.238; 18.CP.240.239; 18.CP.240.154; 18.CP.240.157; 18.CP.240.166; 18.CP.240.169; 18.CP.240.172; 18.CP.240.175; 18.CP.240.240; 18.CP.240.244; 18.CP.244.228; 18.CP.244.229; 18.CP.244.230; 18.CP.244.231; 18.CP.244.236; 18.CP.244.237; 18.CP.244.238; 18.CP.244.239; 18.CP.244.154; 18.CP.244.157; 18.CP.244.166; 18.CP.244.169; 18.CP.244.172; 18.CP.244.175; 18.CP.244.240; 18.CP.244.244;

Prodrugs of 18.EB 18.EB.228.228; 18.EB.228.229; 18.EB.228.230; 18.EB.228.231; 18.EB.228.236; 18.EB.228.237; 18.EB.228.238; 18.EB.228.239; 18.EB.228.154; 18.EB.228.157; 18.EB.228.166; 18.EB.228.169; 18.EB.228.172; 18.EB.228.175; 18.EB.228.240; 18.EB.228.244; 18.EB.229.228; 18.EB.229.229; 18.EB.229.230; 18.EB.229.231; 18.EB.229.236; 18.EB. ,229. ,237; 18.EB.229.238; 18.EB.229.239; 18.EB.229.154; 18.EB.229.157; 18.EB.229.166; 18.EB.229.169; 18. EB.229.172; 18.EB.229.175; 18.EB.229.240; 18.EB.229.244; 18.EB.230.228; 18.EB.230.229; 18.EB.230.230; 18.EB.230.231; 18.EB.230.236; 18.EB.230.237; 18.EB.230.238; 18.EB.230.239; 18.EB.230.154; 18.EB.230.157; 18.EB.230.166; 18.EB.230.169; 18.EB.230.172; 18.EB.230.175; 18.EB.230.240; 18.EB.230.244; 18.EB.231.228; 18.EB.231.229; 18.EB.231.230; 18.EB.231.231; 18.EB.231.236; 18.EB.231.237; 18.EB.231.238; 18.EB.231.239; 18.EB.231.154; 18.EB.231.157; 18.EB.231.166; 18.EB.231.169; 18.EB.231.172; 18.EB.231.175; 18.EB.231.240; 18.EB.231.244; 18.EB.236.228; 18.EB.236.229; 18.EB.236.230; 18.EB.236.231; 18.EB.236.236; 18.EB.236.237; 18.EB.236.238; 18.EB.236.239; 18.EB.236.154; 18.EB.236.157; 18.EB.236.166; 18.EB.236.169; 18.EB.236.172; 18.EB.236.175; 18.EB.236.240; 18.EB.236.244; 18.EB.237.228; 18.EB.237.229; 18.EB.237.230; 18.EB.237.231; 18.EB.237.236; 18.EB.237.237; 18.EB.237.238; 18.EB.237.239; 18.EB.237.154; 18.EB.237.157; 18.EB.237.166; 18.EB.237.169; 18.EB.237.172; 18.EB.237.175; 18.EB.237.240; 18.EB.237.244; 18.EB.238.228; 18.EB.238.229; 18.EB.238.230; 18.EB.238.231; 18.EB.238.236; 18.EB.238.237; 18.EB.238.238; 18.EB.238.239; 18.EB.238.154; 18.EB.238.157; 18.EB.238.166; 18.EB.238.169; 18. EB .238.172; 18.EB.238.175; 18.EB.238.240; 18.EB.238.244; 18.EB.239.228; 18.EB.239.229; 18.EB.239.230; 18.EB.239.231; 18.EB.239.236; 18.EB.239.237; 18.EB.239.238; 18.EB.239.239; 18.EB.239.154; 18.EB.239.157; 18.EB.239.166; 18.EB.239.169; 18. EB.239.172; 18.EB.239.175; 18.EB.239.240; 18.EB.239.244; 18.EB.154.228; 18.EB.154.229; 18.EB.154.230; 18.EB.154.231; 18.EB.154.236; 18.EB.154.237; 18.EB.154.238; 18.EB.154.239; 18.EB.154.154; 18.EB.154.157; 18.EB.154.166; 18.EB.154.169; 18.EB.154.172; 18.EB.154.175; 18.EB.154.240; 18.EB.154.244; 18.EB.157.228; 18.EB.157.229; 18.EB.157.230; 18.EB.157.231; 18.EB.157.236; 18.EB.157.237; 18.EB.157.238; 18.EB.157.239; 18.EB.157.154; 18.EB.157.157; 18.EB.157.166; 18.EB.157.169; 18.EB.157.172; 18.EB.157.175; 18.EB.157.240; 18.EB.157.244; 18.EB.166.228; 18.EB.166.229; 18.EB.166.230; 18.EB.166.231; 18.EB.166.236; 18.EB.166.237; 18.EB.166.238; 18.EB.166.239; 18.EB.166.154; 18.EB.166.157; 18.EB.166.166; 18.EB.166.169; 18.EB.166.172; 18.EB.166.175; 18.EB.166.240; 18.EB.166.244; 18.EB.169.228; 18.EB.169.229; 18.EB.169.230; 18.EB.169.231; 18.EB.169.236; 18.EB.169.237; 18.EB.169.238; 18.EB.169.239; 18.EB.169.154; 18.EB.169.157; 18.EB.169.166; 18.EB.169.169; 18.EB.169.172; 18.EB.169.175; 18.EB.169.240; 18. EB.169.244; 18.EB.172.228; 18.EB.172.229; 18.EB.172.230; 18.EB.172.231; 18.EB.172.236; 18.EB.172.237; 18.EB.172.238; 18.EB.172.239; 18.EB.172.154; 18.EB.172.157; 18.EB.172.166; 18.EB.172.169; 18.EB.172.172; 18.EB.172.175; 18.EB.172.240; 18.EB.172.244; 18. EB.175.228; 18. EB.175.229; 18.EB.175.230; 18.EB.175.231; 18.EB.175.236; 18.EB.175.237; 18.EB.175.238; 18.EB.175.239; 18.EB.175.154; 18.EB.175.157; 18.EB.175.166; 18.EB.175.169; 18.EB.175.172; 18.EB.175.175; 18.EB.175.240; 18.EB.175.244; 18.EB.240.228; 18.EB.240.229; 18.EB.240.230; 18.EB.240.231; 18.EB.240.236; 18.EB.240.237; 18.EB.240.238; 18.EB.240.239; 18.EB.240.154; 18.EB.240.157; 18.EB.240.166; 18.EB.240.169; 18.EB.240.172; 18.EB.240.175; 18.EB.240.240; 18.EB.240.244; 18.EB.244.228; 18.EB.244.229; 18.EB.244.230; 18.EB.244.231; 18.EB.244.236; 18.EB.244.237; 18.EB.244.238; 18.EB.244.239; 18.EB.244.154; 18.EB.244.157; 18.EB.244.166; 18.EB.244.169; 18.EB.244.172; 18.EB.244.175; 18. EB.244.240; 18.EB.244.244;

Prodrugs of 19.B

19.B.228.228; 19.B.228.229; 19.B.228.230; 19.B.228.231; 19.B.228.236; 19.B.228.237; 19.B.228.238; 19.B.228.239; 19.B.228.154; 19.B.228.157; 19.B.228.166; 19.B.228.169; 19.B.228.172; 19.B.228.175; 19.B.228.240; 19.B.228.244; 19.B.229.228; 19.B.229.229; 19.B.229.230; 19.B.229.231; 19.B.229.236; 19.B.229.237; 19.B.229.238; 19.B.229.239; 19.B.229.154; 19.B.229.157; 19.B.229.166; 19.B.229.169; 19.B.229.172; 19.B.229.175; 19.B.229.240; 19.B.229.244; 19.B.230.228; 19.B.230.229; 19.B.230.230; 19.B.230.231; 19.B.230.236; 19.B.23Q.237; 19.B.230.238; 19.B.230.239; 19.B.230.154; 19.B.230.157; 19.B.23Q.166; 19.B.230.169; 19.B.230.172; 19.B.230.175; 19.B.230.240; 19.B.230.244; 19.B.231.228; 19.B.231.229; 19.B.231.230; 19.B.231.231; 19.B.231.236; 19.B.231.237; 19.B.231.238; 19.B.231.239; 19.B.231.154; 19.B.231.157; 19.B.231.166; 19.B.231.169; 19.B.231.172; 19.B.231.175; 19.B.231.240; 19.B.231.244; 19.B.236.228; 19.B.236.229; 19.B.236.230; 19.B.236.231; 19.B.236.236; 19.B.236.237; 19.B.236.238; 19.B.236.239; 19.B.236.154; 19.B.236.157; 19.B.236.166; 19.B.236.169; 19.B.236.172; 19.B.236.175; 19.B.236.240; 19.B.236.244; 19.B.237.228; 19.B.237.229; 19.B.237.230; 19.B.237.231; 19.B.237.236; 19.B.237.237; 19.B.237.238; 19.B.237.239; 19.B.237.154; 19.B.237.157; 19.B.237.166; 19.B.237.169; 19.B.237.172; 19.B.237.175; 19.B.237.240; 19.B.237.244; 19.B.238.228; 19.B.238.229; 19.B.238.230; 19.B.238.231; 19.B.238.236; 19.B.238.237; 19.B.238.238; 19.B.238.239; 19.B.238.154; 19.B.238.157; 19.B.238.166; 19.B.238.169; 19.B.238.172; 19.B.238.175; 19.B.238.240; 19.B.238.244; 19.B.239.228; 19.B.239.229; 19.B.239.230; 19.B.239.231; 19.B.239.236; 19.B.239.237; 19.B.239.238; 19.B.239.239; 19.B.239.154; 19.B.239.157; 19.B.239.166; 19.B.239.169; 19.B.239.172; 19.B.239.175; 19.B.239.240; 19.B.239.244; 19.B.154.228; 19.B.154.229; 19.B.154.230; 19.B.154.231; 19.B.154.236; 19.B.154.237; 19.B.154.238; 19.B.154.239; 19.B.154.154; 19.B.154.157; 19.B.154.166; 19.B.154.169; 19.B.154.172; 19.B.154.175; 19.B.154.240; 19.B.154.244; 19.B.157.228; 19.B.157.229; 19.B.157.230; 19.B.157.231; 19.B.157.236; 19.B.157.237; 19.B.157.238; 19.B.157.239; 19.B.157.154; 19.B.157.157; 19.B.157.166; 19.B.157.169; 19.B.157.172; 19.B.157.175; 19.B.157.240; 19.B.157.244; 19.B.166.228; 19.B.166.229; 19.B.166.230; 19.B.166.231; 19.B.166.236; 19.B.166.237; 19.B.166.238; 19.B.166.239; 19.B.166.154; 19.B.166.157; 19.B.166.166; 19.B.166.169; 19.B.166.172; 19.B.166.175; 19.B.166.240; 19.B.166.244; 19.B.169.228; 19.B.169.229; 19.B.169.230; 19.B.169.231; 19.B.169.236; 19.B.169.237; 19.B.169.238; 19.B.169.239; 19.B.169.154; 19.B.169.157; 19.B.169.166; 19.B.169.169; 19.B.169.172; 19.B.169.175; 19.B.169.240; 19.B.169.244; 19.B.172.228; 19.B.172.229; 19.B.172.230; 19.B.172.231; 19.B.172.236; 19.B.172.237; 19.B.172.238; 19.B.172.239; 19.B.172.154; 19.B.172.157; 19.B.172.166; 19.B.172.169; 19.B.172.172; 19B.V72.V75,' 19.B.172.240; 19.B.172.244; 19.B.175.228; 19.B.175.229; 19.B.175.230; 19.B.175.231; 19.B.175.236; 19.B.175.237; 19.B.175.238; 19.B.175.239; 19.B.175.154; 19.B.175.157; 19.B.175.166; 19.B.175.169; 19.B.175.172; 19.B.175.175; 19.B.175.240; 19.B.175.244; 19.B.240.228; 19.B.240.229; 19.B.240.230; 19.B.240.231; 19.B.240.236; 19.B.240.237; 19.B.240.238; 19.B.240.239; 19.B.240.154; 19.B.240.157; 19.B.240.166; 19.B.240.169; 19.B.240.172; 19.B.240.175; 19.B.240.240; 19.B.240.244; 19.B.244.228; 19.B.244.229; 19.B.244.230; 19.B.244.231; 19.B.244.236; 19.B.244.237; 19.B.244.238; 19.B.244.239; 19.B.244.154; 19.B.244.157; 19.B.244.166; 19.B.244.169; 19.B.244.172; 19.B.244.175; 19.B.244.24Q; 19.B.244.244;

Prodrugs of 19.D

19.D.228.228; 19.D.228.229; 19.D.228.230; 19.D.228.231; 19.D.228.236; 19.D.228.237; 19.D.228.238; 19.D.228.239; 19.D.228.154; 19.D.228.157; 19.D.228.166; 19.D.228.169; 19.D.228.172; 19.D.228.175; 19.D.228.240; 19.D.228.244; 19.D.229.228; 19.D.229.229; 19.D.229.230; 19.D.229.231; 19.D.229.236; 19.D.229.237; 19.D.229.238; 19.D.229.239; 19.D.229.154; 19.D.229.157; 19.D.229.166; 19.D.229.169; 19.D.229.172; 19.D.229.175; 19.D.229.240; 19.D.229.244; 19.D.230.228; 19.D.230.229; 19.D.230.230; 19.D.230.231; 19.D.23Q.236; 19.D.230.237; 19.D.230.238; 19.D.230.239; 19.D.230.154; 19.D.230.157; 19.D.230.166; 19.D.230.169; 19.D.230.172; 19.D.230.175; 19.D.230.24Q; 19.D.230.244; 19.D.231.228; 19.D.231.229; 19.D.231.230; 19.D.231.231; 19.D.231.236; 19.D.231.237; 19.D.231.238; 19.D.231.239; 19.D.231.154; 19.D.231.157; 19.D.231.166; 19.D.231.169; 19.D.231.172; 19.D.231.175; 19.D.231.240; 19.D.231.244; 19.D.236.228; 19.D.236.229; 19JD.236.230; 19.D.236.231; 19.D.236.236; 19.D.236.237; 19.D.236.238; 19.D.236.239; 19.D.236.154; 19.D.236.157; 19.D.236.166; 19.D.236.169; 19.D.236.172; 19.D.236.175; 19.D.236.240; 19.D.236.244; 19.D.237.228; 19.D.237.229; 19.D.237.230; 19.D.237.231; 19.D.237.236; 19.D.237.237; 19.U237.238; 19.D.237.239; 19.D.237.154; 19.D.237.157; 19.D.237.166; 19.D.237.169; 19.D.237.172; 19.D.237.175; 19.D.237.240; 19.D.237.244; 19.D.238.228; 19.D.238.229; 19.D.238.230; 19.D.238.231; 19.D.238.236; 19.D.238.237; 19.D.238.238; 19.D.238.239; 19.D.238.154; 19.D.238.157; 19.D.238.166; 19.D.238.169; 19.D.238.172; 19.D.238.175; 19.D.238.240; 19.D.238.244; 19.D.239.228; 19.D.239.229; 19.D.239.230; 19.D.239.231; 19.D.239.236; 19.D.239.237; 19.D.239.238; 19.D.239.239; 19.D.239.154; 19.D.239.157; 19.D.239.166; 19.D.239.169; 19.D.239.172; 19.D.239.175; 19.D.239.240; 19.D.239.244; 19.D.154.228; 19.D.154.229; 19.D.154.230; 19.D.154.231; 19.D.154.236; 19.D.154.237; 19:D.154.238; 19.D.154.239; 19.D.154.154; 19.D.154.157; 19.D.154.166; 19.D.154.169; 19.D.154.172; 19.D.154.175; 19.D.154.240; 19.D.154.244; 19.D.157.228; 19.D.157.229; 19.D.157.230; 19.D.157.231; 19.D.157.236; 19.D.157.237; 19.D.157.238; 19.D.157.239; 19.D.157.154; 19.D.157.157; 19. ,D.157.166; 19.D.157.169; 19.D.157.172; 19.D.157.175; 19.D.157.240; 19.D.157.244; 19.D.166.228; 19.D.166.229; 19.D.166.230; 19.D.166.231; 19.D.166.236; 19.D.166.237; 19.D.166.238; 19.D.166.239; 19.D.166.154; 19.D.166.157; 19.D.166.166; 19.D.166.169; 19.D.166.172; 19.D.166.175; 19.D.166.240; 19.D.166.244; 19.D.169.228; 19.D.169.229; 19.D.169.230; 19.D.169.231; 19.0.169.236; 19.D.169.237; 19.D.169.238; 19.D.169.239; 19.D.169.154; 19.D.169.157; 19.D.169.166; 19.D.169.169; 19.D.169.172; 19.D.169.175; 19.D.169.240; 19.D.169.244; 19.D.172.228; 19.D.172.229; 19.D.172.230; 19.D.172.231; 19.D.172.236; 19.D.172.237; 19.D.172.238; 19.D.172.239; 19.D.172.154; 19.D.172.157; 19.D.172.166; 19.D.172.169; 19.D.172.172; 19.0.172.175; 19.D.172.240; 19.D.172.244; 19.D.175.228; 19.D.175.229; 19.D.175.230; 19.D.175.231; 19.D.175.236; 19.0.175.237; 19.D.175.238; 19.D.175.239; 19.D.175.154; 19.D.175.157; 19.D.175.166; 19.D.175.169; 19.D.175.172; 19.D.175.175; 19.D.175.24Q; 19.D.175.244; 19.D.240.228; 19.D.240.229; 19.D.240.230; 19.D.240.231; 19.D.240.236; 19.D.240.237; 19.D.240.238; 19.D.240.239; 19.D.240.154; 19.D.240.157; 19.D.240.166; 19.D.240.169; 19.D.240.172; 19.D.240.175; 19.D.240.240; 19.D.240.244; 19.D.244.228; 19.D.244.229; 19.D.244.230; 19.D.244.231; 19.D.244.236; 19.D.244.237; 19.D.244.238; 19.D.244.239; 19.D.244.154; 19.D.244.157; 19.D.244.166; 19.D.244.169; 19.D.244.172; 19.D.244.175; 19.D.244.240; 19.D.244.244;

Prodrugs of 19.AB

19.AB.228.228; 19. AB .228.229; 19.AB.228.230; 19.AB.228.231; 19.AB.228.236; 19.AB.228.237; 19.AB.228.238; 19.AB.228.239; 19.AB.228.154; 19.AB.228.157; 19.AB.228.166; 19.AB.228.169; 19.AB.228.172; 19.AB.228.175; 19.AB.228.240; 19.AB.228.244; 19.AB.229.228; 19.AB.229.229; 19.AB.229.230; 19.AB.229.231; 19.AB.229.236; 19.AB.229.237; 19.AB.229.238; 19.AB.229.239; 19.AB.229.154; 19.AB.229.157; 19. AB.229.166; 19.AB.229.169; 19.AB.229.172; 19.AB.229.175; 19.AB.229.240; 19.AB.229.244; 19.AB.230.228; 19.AB.230.229; 19.AB.230.230; 19.AB.230.231; 19.AB.230.236; 19.AB.230.237; 19.AB.230.238; 19.AB.230.239; 19.AB.230.154; 19.AB.230.157; 19.AB.230.166; 19.AB.230.169; 19.AB.230.172; 19.AB.230.175; 19.AB.230.240; 19.AB.230.244; 19.AB.231.228; 19.AB.231.229; 19.AB.231.230; 19.AB.231.231; 19.AB.231.236; 19.AB.231.237; 19.AB.231.238; 19.AB.231.239; 19.AB.231.154; 19.AB.231.157; 19.AB.231.166; 19.AB.231.169; 19.AB.231.172; 19.AB.231.175; 19.AB.231.24Q; 19.AB.231.244; 19.AB.236.228; 19.AB.236.229; 19.AB.236.230; 19.AB.236.231; 19.AB.236.236; 19.AB.236.237; 19.AB.236.238; 19.AB.236.239; 19.AB.236.154; 19.AB.236.157; 19.AB.236.166; 19.AB.236.169; 19.AB.236.172; 19.AB.236.175; 19.AB.236.240; 19.AB.236.244; 19.AB.237.228; 19.AB.237.229; 19.AB.237.230; 19.AB.237.231; 19.AB.237.236; 19.AB.237.237; 19.AB.237.238; 19.AB.237.239; 19.AB.237.154; 19.AB.237.157; 19.AB.237.166; 19. AB.237.169; 19.AB.237.172; 19.AB.237.175; 19.AB.237.240; 19.AB.237.244; 19.AB.238.228; 19.AB.238.229; 19.AB.238.230; 19.AB.238.231; 19.AB.238.236; 19.AB.238.237; 19.AB.238.238; 19.AB.238.239; 19.AB.238.154; 19.AB.238.157; 19. AB.238.166; 19.AB.238.169; 19.AB.238.172; 19.AB.238.175; 19.AB.238.240; 19.AB.238.244; 19.AB.239.228; 19.AB.239.229; 19.AB.239.230; 19.AB.239.231; 19.AB.239.236; 19.AB.239.237; 19.AB.239.238; 19.AB.239.239; 19.AB.239.154; 19.AB.239.157; 19.AB.239.166; 19.AB.239.169; 19. AB.239.172; 19.AB.239.175; 19.AB.239.240; 19.AB.239.244; 19.AB.154.228; 19.AB.154.229; 19.AB.154.230; 19.AB.154.231; 19.AB.154.236; 19.AB.154.237; 19.AB.154.238; 19.AB.154.239; 19.AB.154.154; 19.AB.154.157; 19.AB.154.166; 19.AB.154.169; 19.AB.154.172; 19.AB.154.175; 19.AB.154.240; 19.AB.154.244; 19.AB.157.228; 19.AB.157.229; 19.AB.157.230; 19.AB.157.231; 19.AB.157.236; 19.AB.157.237; 19.AB.157.238; 19.AB.157.239; 19.AB.157.154; 19.AB.157.157; 19.AB.157.166; 19.AB.157.169; 19.AB.157.172; 19.AB.157.175; 19.AB.157.240; 19.AB.157.244; 19.AB.166.228; 19.AB.166.229; 19.AB.166.23Q; 19.AB.166.231; 19.AB.166.236; 19.AB.166.237; 19.AB.166.238; 19. AB.166.239; 19.AB.166.154; 19.AB.166.157; 19.AB.166.166; 19.AB.166.169; 19.AB.166.172; 19.AB.166.175; 19.AB.166.240; 19.AB.166.244; 19.AB.169.228; 19.AB.169.229; 19.AB.169.230; 19.AB.169.231; 19.AB.169.236; 19.AB.169.237; 19. AB.169.238; 19.AB.169.239; 19.AB.169.154; 19.AB.169.157; 19.AB.169.166; 19.AB.169.169; 19.AB.169.172; 19.AB.169.175; 19.AB.169.240; 19.AB.169.244; 19.AB.172.228; 19.AB.172.229; 19.AB.172.230; 19.AB.172.231; 19.AB.172.236; 19.AB.172.237; 19.AB.172.238; 19.AB.172.239; 19.AB.172.154; 19.AB.172.157; 19.AB.172.166; 19.AB.172.169; 19.AB.172.172; 19.AB.172.175; 19.AB.172.24Q; 19.AB.172.244; 19.AB.175.228; 19. AB.175.229; 19.AB.175.230; 19.AB.175.231; 19.AB.175.236; 19.AB.175.237; 19.AB.175.238; 19.AB.175.239; 19.AB.175.154; 19.AB.175.157; 19.AB.175.166; 19.AB.175.169; 19.AB.175.172; 19.AB.175.175; 19.AB.175.24Q; 19.AB.175.244; 19. AB.240.228; 19.AB.240.229; 19.AB.240.230; 19.AB.240.231; 19.AB.240.236; 19.AB.240.237; 19.AB.240.238; 19.AB.240.239; 19.AB.240.154; 19.AB.240.157; 19.AB.240.166; 19.AB.240.169; 19.AB.240.172; 19.AB.240.175; 19.AB.240.240; 19.AB.240.244; 19.AB.244.228; 19.AB.244.229; 19.AB.244.230; 19.AB.244.231; 19.AB.244.236; 19.AB.244.237; 19.AB.244.238; 19. AB .244.239; 19.AB.244.154; 19.AB.244.157; 19.AB.244.166; 19.AB.244.169; 19.AB.244.172; 19.AB.244.175; 19.AB.244.240; 19.AB.244.244;

Prodrugs of 19.BI

19.BI.228.228; 19.BI.228.229; 19.BI.228.230; 19.BI.228.231; 19.BI.228.236; 19.BI.228.237; 19.BI.228.238; 19.BI.228.239; 19.BI.228.154; 19.BI.228.157; 19.BI.228.166; 19.BI.228.169; 19.BI.228.172; 19.BI.228.175; 19.BI.228.240; 19.BI.228.244; 19.BI.229.228; 19.BI.229.229; 19.BI.229.230; 19.BI.229.231; 19.BI.229.236; 19.BI.229.237; 19.BI.229.238; 19.BI.229.239; 19.BI.229.154; 19.BI.229.157; 19.BI.229.166; 19.BI.229.169; 19.BI.229.172; 19.BI.229.175; 19.BI.229.240; 19.BI.229.244; 19.BI.230.228; 19.BI.230.229; 19.BI.230.230; 19.BI.230.231; 19.BI.230.236; 19.BI.230.237; 19.BI.23Q.238; 19.BI.230.239; 19.BI.230.154; 19.BI.230.157; 19.BI.230.166; 19.BI.230.169; 19.BI.230.172; 19.BI.230.175; 19.BI.230.240; 19.BI.230.244; 19.BI.231.228; 19.BI.231.229; 19.BI.231.230; 19.BI.231.231; 19.BI.231.236; 19.BI.231.237; 19.BI.231.238; 19.BI.231.239; 19.BI.231.154; 19.BI.231.157; 19.BI.231.166; 19.BI.231.169; 19.BI.231.172; 19.BI.231.175; 19.BI.231.240; 19.BI.231.244; 19.BI.236.228; 19.BI.236.229; 19.BI.236.230; 19.BI.236.231; 19.BI.236.236; 19.BI.236.237; 19.BI.236.238; 19.BI.236.239; 19.BI.236.154; 19.BI.236.157; 19.BI.236.166; 19.BI.236.169; 19.BI.236.172; 19.BI.236.175; 19.BI.236.24Q; 19.BI.236.244; 19.BI.237.228; 19.BI.237.229; 19.BI.237.230; 19.BI.237.231; 19.BI.237.236; 19.BI.237.237; 19.BI.237.238; 19.BI.237.239; 19.BI.237.154; 19.BI.237.157; 19.BI.237.166; 19.BI.237.169; 19.BI.237.172; 19.BI.237.175; 19.BI.237.240; 19.BI.237.244; 19.BI.238.228; 19.BI.238.229; 19.BI.238.230; 19.BI.238.231; 19.BI.238.236; 19.BI.238.237; 19.BI.238.238; 19.BI.238.239; 19.BI.238.154; 19.BI.238.157; 19.BI.238.166; 19.BI.238.169; 19.BI.238.172; 19.BI.238.175; 19.BI.238.240; 19.BI.238.244; 19.BI.239.228; 19.BI.239.229; 19.BI.239.230; 19.BI.239.231; 19.BI.239.236; 19.BI.239.237; 19.BI.239.238; 19.BI.239.239; 19.BI.239.154; 19.BI.239.157; 19.BI.239.166; 19.BI.239.169; 19.BI.239.172; 19.BI.239.175; 19.BI.239.240; 19.BI.239.244; 19.BI.154.228; 19.BI.154.229; 19.BI.154.230; 19.BI.154.231; 19.BI.154.236; 19.BI.154.237; 19.BI.154.238; 19.BI.154.239; 19.BI.154.154; 19.BI.154.157; 19.BI.154.166; 19.BI.154.169; 19.BI.154.172; 19.BI.154.175; 19.BI.154.240; 19.BI.154.244; 19.BI.157.228; 19.BI.157.229; 19.BI.157.230; 19.BI.157.231; 19.BI.157.236; 19.BI.157.237; 19.BI.157.238; 19.BI.157.239; 19.BI.157.154; 19.BI.157.157; 19.BI.157.166; 19.BI.157.169; 19.BI.157.172; 19.BI.157.175; 19.BI.157.240; 19.BI.157.244; 19.BI.166.228; 19.BI.166.229; 19.BI.166.230; 19.BI.166.231; 19.BI.166.236; 19.BI.166.237; 19.BI.166.238; 19.BI.166.239; 19.BI.166.154; 19.BI.166.157; 19.BI.166.166; 19.BI.166.169; 19.BI.166.172; 19.BI.166.175; 19.BI.166.240; 19.BI.166.244; 19.BI.169.228; 19.BI.169.229; 19.BI.169.230; 19.BI.169.231; 19.BI.169.236; 19.BI.169.237; 19.BI.169.238; 19.BI.169.239; 19.BI.169.154; 19.BL169.157; 19.BI.169.166; 19.BI.169.169; 19.BI.169.172; 19.BI.169.175; 19.BL169.240; 19.BI.169.244; 19.BI.172.228; 19.BI.172.229; 19.BI.172.230; 19.BL172.231; 19.BI.172.236; 19.BI.172.237; 19.BI.172.238; 19.BI.172.239; 19.BI.172.154; 19.BI.172.157; 19.BI.172.166; 19.BI.172.169; 19.BI.172.172; 19.BI.172.175; 19.BI.172.240; 19.BI.172.244; 19.BL175.228; 19.BI.175.229; 19.BI.175.230; 19.BI.175.231; 19.BI.175.236; 19.BL175.237; 19.BI.175.238; 19.BI.175.239; 19.BI.175.154; 19.BI.175.157; 19.BL175.166; 19.BI.175.169; 19.BI.175.172; 19.BI.175.175; 19.BI.175.240; 19.BI.175.244; 19.BI.240.228; 19.BI.240.229; 19.BI.240.230; 19.BI.240.231; 19.BI.240.236; 19.BI.240.237; 19.BI.240.238; 19.BI.240.239; 19.BI.240.154; 19.BI.240.157; 19.BI.240.166; 19.BI.240.169; 19.BI.240.172; 19.BI.240.175; 19.BI.240.240; 19.BI.240.244; 19.BI.244.228; 19.BI.244.229; 19.BI.244.230; 19.BI.244.231; 19.BI.244.236; 19.BI.244.237; 19.BI.244.238; 19.BI.244.239; 19.BI.244.154; 19.BI.244.157; 19.BI.244.166; 19.BI.244.169; 19.BI.244.172; 19.BI.244.175; 19.BI.244.240; 19.BI.244.244;

Prodrugs of 19.1

19.1.228.228; 19.1.228.229; 19.1.228.230; 19.1.228.231; 19.1.228-236; 19.1.228.237; 19.1.228.238; 19.1.228.239; 19.1.228.154; 19.1.228.157; 19.1.228.166; 19.1.228.169; 19.1.228.172; 19.1.228.175; 19.1.228.240; 19.1.228.244; 19.1.229.228; 19.1.229.229; 19.1.229.230; 19.1.229.231; 19.1.229.236; 19.1.229.237; 19.1.229.238; 19.1.229.239; 19.1.229.154; 19.1.229.157; 19.1.229.166; 19.1.229.169; 19.1.229.172; 19.1.229.175; 19.1.229.240; 19.1.229.244; 19.1.230.228; 19.1.230.229; 19.1.230.230; 19.1.230.231; 19.1.230.236; 19.1.230.237; 19.1.230.238; 19.1.230.239; 19.1230.154; 19.1.230.157; 19.1.230.166; 19.1.230.169; 19.1.230.172; 19.1.230.175; 19.1.230.240; 19.1.230.244; 19.1.231.228; 19.1.231.229; 19.1.231.230; 19.1.231.231; 19.1.231.236; 19.1.231.237; 19.1.231.238; 19.1.231.239; 19.1.231.154; 19.1.231.157; 19.1.231.166; 19.1.231.169; 19.1.231.172; 19.1.231.175; 19.1.231.240; 19.1.231.244; 19.1.236.228; 19.1.236.229; 19.1.236.230; 19.1.236.231; 19.1.236.236; 19.1.236.237; 19.1.236.238; 19.1.236.239; 19.1.236.154; 19.1.236.157; 19.1.236.166; 19.1.236.169; 19.1.236.172; 19.1.236.175; 19.1.236.240; 19.1.236.244; 19.1.237.228; 19.1.237.229; 19.1.237.230; 19.1.237.231; 19.1.237.236; 19.1.237.237; 19.1.237.238; 19.1.237.239; 19.1.237.154; 19.1.237.157; 19.1.237.166; 19.1.237.169; 19.1.237.172; 19.1.237.175; 19.1.237.240; 19.1.237.244; 19.1.238.228; 19.1.238.229; 19.1.238.230; 19.1.238.231; 19.1.238.236; 19.1.238.237; 19.1.238.238; 19.1.238.239; 19.1.238.154; 19.1.238.157; 19.1.238.166; 19.1.238.169; 19.1.238.172; 19.1.238.175; 19.1.238.240; 19.1.238.244; 19.1.239.228; 19.1.239.229; 19.1.239.230; 19.1.239.231; 19.1.239.236; 19.1.239.237; 19.1.239.238; 19.1.239.239; 19.1.239.154; 19.1.239.157; 19.1.239.166; 19.1.239.169; 19.1.239.172; 19.1.239.175; 19.1.239.240; 19.1.239.244; 19.1.154.228; 19.1.154.229; 19.1.154.230; 19.1.154.231; 19.1.154.236; 19.1.154.237; 19.1.154.238; 19.1.154.239; 19.1.154.154; 19.1.154.157; 19.1.154.166; 19.1.154.169; 19.1.154.172; 19.1.154.175; 19.1.154.240; 19.1.154.244; 19.1.157.228; 19.1.157.229; 19.1.157.230; 19.1.157.231; 19.1.157.236; 19.1.157.237; 19.1.157.238; 19.1.157.239; 19.1.157.154; 19.1.157.157; 19.1.157.166; 19.1.157.169; 19.1.157.172; 19.1.157.175; 19.1.157.240; 19.1.157.244; 19.1.166.228; 19.1.166.229; 19.1.166.230; 19.1.166.231; 19.1.166.236; 19.1.166.237; 19.1.166.238; 19.1.166.239; 19.1.166.154; 19.1.166.157; 19.1.166.166; 19.1.166.169; 19.1.166.172; 19.1.166.175; 19.1.166.240; 19.1.166.244; 19.1.169.228; 19.1.169.229; 19.1.169.230; 19.1.169.231; 19.1.169.236; 19.1.169.237; 19.1.169.238; 19.1.169.239; 19.1.169.154; 19.1.169.157; 19.1.169.166; 19.1.169.169; 19.1.169.172; 19.1.169.175; 19.1.169.240; 19.1.169.244; 19.1.172.228; 19.1.172.229; 19.1.172.230; 19.1.172.231; 19.1.172.236; 19.1.172.237; 19.1.172.238; 19.1.172.239; 19.1.172.154; 19.1.172.157; 19.1.172.166; 19.1.172.169; 19.1.172.172; 19.1.172.175; 19.1.172.240; 19.1.172.244; 19.1.175.228; 19.1.175.229; 19.1.175.230; 19.1.175.231; 19.1.175.236; 19.1.175.237; 19.1.175.238; 19.1.175.239; 19.1.175.154; 19.1.175.157; 19.1.175.166; 19.1.175.169; 19.1.175.172; 19.1.175.175; 19.1.175.240; 19.1.175.244; 19.1.240.228; 19.1.240.229; 19.1.240.230; 19.1.240.231; 19.1.240.236; 19.1.240.237; 19.1.240.238; 19.1.240.239; 19.1.240.154; 19.1.240.157; 19.1.240.166; 19.1.240.169; 19.1.240.172; 19.1.240-175; 19.1.240.240; 19.1.240.244; 19.1.244.228; 19.1.244.229; 19.1.244.230; 19.1.244.231; 19.1.244.236; 19.1.244.237; 19.1.244.238; 19.1.244.239; 19.1.244.154; 19.1.244.157; 19.1.244.166; 19.1.244.169; 19.1.244.172; 19.1.244.175; 19.1.244.240; 19.1.244.244;

Prodrugs of 19.T

19J.228.228; 19.J.228.229; 19.J.228.230; 19.J.228.231; 19.J.228.236; 19.J.228.237; 19.J.228.238; 19.J.228.239; 19.J.228.154; 19.J.228.157; 19.J.228.166; 19.J.228.169; 19.J.228.172; 19.J.228.175; 19.J.228.240; 19.J.228.244; 19J.229.228; 19.J.229.229; 19J.229.230; 19J.229.231; 19J.229.236; 19J.229.237; 19J.229.238; 19J.229.239; 19J.229.154; 19J.229.157; 19J.229.166; 19J.229.169; 19J.229.172; 19J.229.175; 19.J.229.240; 19J.229.244; 19J.230.228; 19J.230.229; 19J.230.230; 19J.230.231; 19J.230.236; 19J.230.237; 19J.230.238; 19J.230.239; 19J.230.154; 19.J.230.157; 19J.230.166; 19J.230.169; 19J.230.172; 19J.230.175; 19J.230.240; 19J.230.244; 19J.231.228; 19J.231.229; 19J.231.230; 19J.231.231; 19J.231.236; 19J.231.237; 19J.231.238; 19J.231.239; 19J.231.154; 19J.231.157; 19J.231.166; 19J.231.169; 19J.231.172; 19J.231.175; 19J.231.240; 19J.231.244; 19J.236.228; 19J.236.229; 19J.236.230; 19J.236.231; 19J.236.236; 19.J.236.237; 19J.236.238; 19J.236.239; 19J.236.154; 19J.236.157; 19J.236.166; 19J.236.169; 19J.236.172; 19J.236.175; 19J.236.240; 19J.236.244; 19J.237.228; 19J.237.229; 19J.237.230; 19J.237.231; 19J.237.236; 19J.237.237; 19J.237.238; 19J.237.239; 19J.237.154; 19J.237.157; 19J.237.166; 19J.237.169; 19J.237.172; 19J.237.175; 19J.237.240; 19J.237.244; 19.J.238.228; 19.J.238.229; 19.J.238.230; 19.J.238.231; 19.J.238.236; 19.J.238.237; 19.J.238.238; 19.J.238.239; 19.J.238.154; 19.J.238.157; 19J.238.166; 19.J.238.169; 19J.238.172; 19J.238.175; 19J.238.240; 19J.238.244; 19J.239.228; 19J.239.229; 19J.239.230; 19J.239.231; 19J.239.236; 19J.239.237; 19J.239.238; 19J.239.239; 19J.239.154; 19J.239.157; 19J.239.166; 19.J.239.169; 19J.239.172; 19J.239.175; 19J.239.240; 19J.239.244; 19J.154.228; 19.J.154.229; 19J.154.230; 19J.154.231; 19J.154.236; 19J.154.237; 19J.154.238; 19.J.154.239; 19J.154.154; 19J.154.157; 19J.154.166; 19J.154.169; 19J.154.172; 19J.154.175; 19J.154.240; 19J.154.244; 19J.157.228; 19J.157.229; 19J.157.230; 19J.157.231; 19'J^'.157'.236; 19J.157.237; 19J.157.238; 19.J.157.239; 19J.157.154; 19.J.157.157; 19J.157.166; 19J.157.169; 19J.157.172; 19J.157.175; 19J.157.240; 19J.157.244; 19J.166.228; 19J.166.229; 19J.166.230; 19J.166.231; 19J.166.236; 19J.166.237; 19J.166.238; 19J.166.239; 19J.166.154; 19J.166.157; 19J.166.166; 19J.166.169; 19J.166.172; 19J.166.175; 19J.166.240; 19J.166.244; 19J.169.228; 19J.169.229; 19J.169.230; 19J.169.231; 19J.169.236; 19J.169.237; 19.J.169.238; 19J.169.239; 19J.169.154; 19J.169.157; 19J.169.166; 19J.169.169; 19J.169.172; 19J.169.175; 19J.169.240; 19J.169.244; 19J.172.228; 19J.172.229; 19J.172.230; 19J.172.231; 19J.172.236; 19J.172.237; 19J.172.238; 19J.172.239; 19J.172.154; 19J.172.157; 19J.172.166; 19J.172.169; 19J.172.172; 19J.172.175; 19J.172.240; 19J.172.244; 19J.175.228; 19J.175.229; 19J.175.230; 19J.175.231; 19J.175.236; 19J.175.237; 19J.175.238; 19J.175.239; 19J.175.154; 19J.175.157; 19J.175.166; 19J.175.169; 19J.175.172; 19J.175.175; 19J.175.240; 19J.175.244; 19J.240.228; 19J.240.229; 19J.240.230; 19J.240.231; 19J.240.236; 19J.240.237; 19J.240.238; 19J.240.239; 19J.240.154; 19J.240.157; 19J.240.166; 19J.240.169; 19J.240.172; 19J.240.175; 19J.240.240; 19J.240.244; 19.J.244.228; 19J.244.229; 19J.244.230; 19J.244.231; 19J.244.236; 19J.244.237; 19J.244.238; 19J.244.239; 19J.244.154; 19J.244.157; 19J.244.166; 19J.244.169; 19J.244.172; 19J.244.175; 19J.244.240; 19J.244.244;

Prodrugs of 19.L

19.L.228.228; 19.L.228.229; 19.L.228.230; 19.L.228.231; 19.L.228.236; 19.L.228.237; 19.L.228.238; 19.L.228.239; 19.L.228.154; 19.L.228.157; 19.L.228.166; 19.L.228.169; 19.L.228.172; 19.L.228.175; 19.L.228.240; 19.L.228.244; 19.L.229.228; 19.L.229.229; 19.L.229.230; 19.L.229.231; 19X.229.236; 19.L.229.237; 19.L.229.238; 19.L.229.239; 19.L.229.154; 19.L.229.157; 19.L.229.166; 19.L.229.169; 19.L.229.172; 19.L.229.175; 19.L.229.240; 19.L.229.244; 19.L.230.228; 19.L.230.229; 19.L.230.230; 19.L.230.231; 19.L.230.236; 19.L.230.237; 19.L.230.238; 19.L.230.239; 19.L.230.154; 19.L.230.157; 19.L.230.166; 19.L.230.169; 19.L.23Q.172; 19.L.230.175; 19.L.230.240; 19.L.230.244; 19.L.231.228; 19.L.231.229; 19.L.231.230; 19.L.231.231; 19.L.231.236; 19.L.231.237; 19.L.231.238; 19.L.231.239; 19.L.231.154; 19.L.231.157; 19.L.231.166; 19.L.231.169; 19.L.231.172; 19.L.231.175; 19.L.231.240; 19.L.231.244; 19.L.236.228; 19.L.236.229; 19.L.236.230; 19.L.236.231; 19.L.236.236; 19.L.236.237; 19.L.236.238; 19.L.236.239; 19.L.236.154; 19.L.236.157; 19.L.236.166; 19.L.236.169; 19.L.236.172; 19.L.236.175; 19.L.236.240; 19.L.236.244; 19.L.237.228; 19.L.237.229; 19.L.237.230; 19.L.237.231; 19.L.237.236; 19.L.237.237; 19.L.237.238; 19.L.237.239; 19.L.237.154; 19.L.237.157; 19.L.237.166; 19.L.237.169; 19.L.237.172; 19.L.237.175; 19.L.237.240; 19.L.237.244; 19.L.238.228; 19.L.238.229; 19.L.238.230; 19.L.238.231; 19.L.238.236; 19.L.238.237; 19.L.238.238; 19.L.238.239; 19.L.238.154; 19.L.238.157; 19.L.238.166; 19.L.238.169; 19.L.238.172; 19.L.238.175; 19.L.238.240; 19.L.238.244; 19.L.239.228; 19.L.239.229; 19.L.239.230; 19.L.239.231; 19.L.239.236; 19.L.239.237; 19.L.239.238; 19.L.239.239; 19.L.239.154; 19.L.239.157; 19.L.239.166; 19.L.239.169; 19.L.239.172; 19.L.239.175; 19.L.239.240; 19.L.239.244; 19.L.154.228; 19.L.154.229; 19.L.154.230; 19.L.154.231; 19.L.154.236; 19.L.154.237; 19.L.154.238; 19.L.154.239; 19.L.154.154; 19.L.154.157; 19.L.154.166; 19.L.154.169; 19.L.154.172; 19X.154.175; 19.L.154.240; 19.L.154.244; 19.L.157.228; 19.L.157.229; 19.L.157.230; 19.L.157.231; 19.L.157.236; 19.L.157.237; 19.L.157.238; 19.L.157.239; 19.L.157.154; 19.L.157.157; 19.L.157.166; 19.L.157.169; 19.L.157.172; 19.L.157.175; 19.L.157.240; 19.L.157.244; 19.L.166.228; 19.L.166.229; 19.L.166.230; 19.L.166.231; 19.L.166.236; 19.L.166.237; 19.L.166.238; 19.L.166.239; 19.L.166.154; 19.L.166.157; 19.L.166.166; 19.L.166.169; 19.L.166.172; 19.L.166.175; 19.L.166.240; 19.L.166.244; 19.L.169.228; 19.L.169.229; 19.L.169.230; 19.L.169.231; 19.L.169.236; 19.L.169.237; 19.L.169.238; 19.L.169.239; 19.L.169.154; 19.L.169.157; 19.L.169.166; 19.L.169.169; 19.L.169.172; 19.L.169.175; 19.L.169.240; 19.L.169.244; 19.L.172.228; 19.L.172.229; 19.L.172.230; 19.L.172.231; 19.L.172.236; 19.L.172.237; 19.L.172.238; 19.L.172.239; 19.L.172.154; 19.L.172.157; 19.L.172.166; 19.L.172.169; 19.L.172.172; 19.L.172.175; 19.L.172.240; 19.L.172.244; 19.L.175.228; 19.L.175.229; 19.L.175.230; 19.L.175.231; 19.L.175.236; 19.L.175.237; 19.L.175.238; 19.L.175.239; 19.L.175.154; 19.L.175.157; 19.L.175.166; 19.L.175.169; 19.L.175.172; 19.L.175.175; 19.L.175.240; 19.L.175.244; 19.L.240.228; 19.L.240.229; 19.L.24Q.230; 19.L.240.231; 19.L.240.236; 19.L.240.237; 19.L.240.238; 19.L.240.239; 19.L.240.154; 19.L.240.157; 19.L.240.166; 19.L.240.169; 19.L.240.172; 19.L.240.175; 19.L.240.240; 19.L.240.244; 19.L.244.228; 19.L.244.229; 19.L.244.230; 19.L.244.231; 19.L.244.236; 19.L.244.237; 19.L.244.238; 19.L.244.239; 19.L.244.154; 19.L.244.157; 19.L.244.166; 19.L.244.169; 19.L.244.172; 19.L.244.175; 19.L.244.240; 19.L.244.244;

Prodrugs of 19.0

19.O.228.228; 19.O.228.229; 19.O.228.230; 19.0.228.231; 19.O.228.236; 19.O.228.237; 19.O.228.238; 19.O.228.239; 19.O.228.154; 19.O.228.157; 19.O.228.166; 19.O.228.169; 19.O.228.172; 19.O.228.175; 19.O.228.240; 19.O.228.244; 19.O.229.228; 19.O.229.229; 19.O.229.230; 19.O.229.231; 19.O.229.236; 19.O.229.237; 19.O.229.238; 19.O.229.239; 19.O.229.154; 19.O.229.157; 19.O.229.166; 19.O.229.169; 19.O.229.172; 19.O.229.175; 19.O.229.240; 19.O.229.244; 19.O.230.228; 19.O.230.229; 19.O.230.23Q; 19.O.230.231; 19.O.230.236; 19.O.230.237; 19.O.230.238; 19.O.230.239; 19.O.230.154; 19.O.230.157; 19.O.230.166; 19.O.230.169; 19.O.230.172; 19.O.230.175; 19.O.230.240; 19.O.230.244; 19.O.231.228; 19.O.231.229; 19.O.231.230; 19.O.231.231; 19.O.231.236; 19.O.231.237; 19.O.231.238; 19.O.231.239; 19.O.231.154; 19.O.231.157; 19.O.231.166; 19.O.231.169; 19.O.231.172; 19.O.231.175; 19.O.231.240; 19.O.231.244; 19.O.236.228; 19.O.236.229; 19.O.236.230; 19.O.236.231; 19.O.236.236; 19.O.236.237; 19.O.236.238; 19.O.236.239; 19.O.236.154; 19.O.236.157; 19.O.236.166; 19.O.236.169; 19.O.236.172; 19.O.236.175; 19.O.236.240; 19.O.236.244; 19.O.237.228; 19.O.237.229; 19.O.237.230; 19.O.237.231; 19.O.237.236; 19.O.237.237; 19.O.237.238; 19.O.237.239; 19.O.237.154; 19.O.237.157; 19.O.237.166; 19.O.237.169; 19.O.237.172; 19.O.237.175; 19.O.237.240; 19.O.237.244; 19.O.238.228; 19.O.238.229; 19.O.238.230; 19.O.238.231; 19.O.238.236; 19.O.238.237; 19.O.238.238; 19.O.238.239; 19.O.238.154; 19.O.238.157; 19.O.238.166; 19.O.238.169; 19.O.238.172; 19.O.238.175; 19.O.238.240; 19.O.238.244; 19.O.239.228; 19.O.239.229; 19.O.239.230; 19.O.239.231; 19.O.239.236; 19.O.239.237; 19.O.239.238; 19.O.239.239; 19.O.239.154; 19.O.239.157; 19.O.239.166; 19.O.239.169; 19.O.239.172; 19.O.239.175; 19.O.239.240; 19.O.239.244; 19.O.154.228; 19.O.154.229; 19.O.154.230; 19.O.154.231; 19.O.154.236; 19.O.154.237; 19.O.154.238; 19.O.154.239; 19.O.154.154; 19.O.154.157; 19.O.154.166; 19.O.154.169; 19.O.154.172; 19.O.154.175; 19.O.154.240; 19.O.154.244; 19.O.157.228; 19.O.157.229; 19.O.157.230; 19.0157.231; 19.O.157.236; 19.O.157.237; 19.O.157.238; 19.O.157.239; 19.O.157.154; 19.O.157.157; 19.O.157.166; 19.0.157.169; 19.O.157.172; 19.O.157.175; 19.O.157.240; 19.O.157.244; 19.O.166-228; 19.O.166.229; 19.O.166.230; 19.O.166.231; 19.O.166.236; 19.O.166.237; 19.O.166.238; 19.O.166.239; 19.O.166.154; 19.O.166.157; 19.O.166.166; 19.O.166.169; 19.O.166.172; 19.O.166.175; 19.O.166.240; 19.O.166.244; 19.O.169.228; 19.O.169.229; 19.O.169.230; 19.O.169.231; 19.O.169.236; 19.O.169.237; 19.O.169.238; 19.O.169.239; 19.O.169.154; 19.O.169.157; 19.O.169.166; 19.O.169.169; 19.O.169.172; 19.O.169.175; 19.O.169.240; 19.0.169.244; 19.O.172.228; 19.O.172.229; 19.O.172.230; 19.O.172.231; 19.O.172.236; 19.O.172.237; 19.O.172.238; 19.O.172.239; 19.O.172.154; 19.O.172.157; 19.O.172.166; 19.O.172.169; 19.O.172.172; 19.O.172.175; 19.O.172.240; 19.O.172.244; 19.O.175.228; 19.O.175.229; 19.O.175.230; 19.O.175.231; 19.O.175.236; 19.O.175.237; 19.O-175.238; 19.O.175.239; 19.O.175.154; 19.O.175.157; 19.O.175.166; 19.O.175.169; 19.O.175.172; 19.O.175.175; 19.O.175.240; 19.O.175.244; 19.O.240.228; 19.O.240.229; 19.O.240.230; 19.O.240.231; 19.O.240.236; 19.O.240.237; 19.O.240.238; 19.O.240.239; 19.O-24Q.154; 19.O.240.157; 19.O.240.166; 19.O.240.169; 19.O.24Q.172; 19.O.240.175; 19.O.240.240; 19.O.240.244; 19.O.244.228; 19.O.244.229; 19.O.244.230; 19.O.244.231; 19.O.244.236; 19.O.244.237; 19.O.244.238; 19.O.244.239; 19.O.244.154; 19.O.244.157; 19.O.244.166; 19.O.244.169; 19.O.244.172; 19.O.244.175; 19.O.244.240; 19.O.244.244;

Prodrugs of 19.P

19.P.228.228; 19.P.228.229; 19.P.228.23Q; 19.P.228.231; 19.P.228.236; 19.P.228.237; 19.P.228.238; 19.P.228.239; 19.P.228.154; 19.P.228.157; 19.P.228.166; 19.P.228.169; 19.P.228.172; 19.P.228.175; 19.P.228.240; 19.P.228.244; 19.P.229.228; 19.P.229.229; 19.P.229.230; 19.P.229.231; 19.P.229.236; 19.P.229.237; 19.P.229.238; 19.P.229.239; 19.P.229.154; 19.P.229.157; 19.P.229.166; 19.P.229.169; 19.P.229.172; 19.P.229.175; 19.P.229.240; 19.P.229.244; 19.P.230.228; 19.P.230.229; 19.P.230.230; 19.P.230.231; 19.P.230.236; 19.P.230.237; 19.P.230.238; 19.P.230.239; 19.P.230.154; 19.P.230.157; 19.P.230.166; 19.P.230.169; 19.P.230.172; 19.P.230.175; 19.P.230.240; 19.P.230.244; 19.P.231.228; 19.P.231.229; 19.P.231.230; 19.P.231.231; 19.P.231.236; 19.P.231.237; 19.P.231.238; 19.P.231.239; 19.P.231.154; 19.P.231.157; 19.P.231.166; 19.P.231.169; 19.P.231.172; 19.P.231.175; 19.P.231.240; 19.P.231.244; 19.P.236.228; 19.P.236.229; 19.P.236.230; 19.P.236.231; 19.P.236.236; 19.P.236.237; 19.P.236.238; 19.P.236.239; 19.P.236.154; 19.P.236.157; 19.P.236.166; 19.P.236.169; 19.P.236.172; 19.P.236.175; 19.P.236.240; 19.P.236.244; 19.P.237.228; 19.P.237.229; 19.P.237.230; 19.P.237.231; 19.P.237.236; 19.P.237.237; 19.P.237.238; 19.P.237.239; 19.P.237.154; 19.P.237.157; 19.P.237.166; 19.P.237.169; 19.P.237.172; 19.P.237.175; 19.P.237.240; 19.P.237.244; 19.P.238.228; 19.P.238.229; 19.P.238.230; 19.P.238.231; 19.P.238.236; 19.P.238.237; 19.P.238.238; 19.P.238.239; 19.P.238.154; 19.P.238.157; 19.P.238.166; 19.P.238.169; 19.P.238.172; 19.P.238.175; 19.P.238.240; 19.P.238.244; 19.P.239.228; 19.P.239.229; 19.P.239.230; 19.P.239.231; 19.P.239.236; 19.P.239.237; 19.P.239.238; 19.P.239.239; 19.P.239.154; 19.P.239.157; 19.P.239.166; 19.P.239.169; 19.P.239.172; 19.P.239.175; 19.P.239.240; 19.P.239.244; 19.P.154.228; 19.P.154.229; 19.P.154.230; 19.P.154.231; 19.P.154.236; 19.P.154.237; 19.P.154.238; 19.P.154.239; 19.P.154.154; 19.P.154.157; 19.P.154.166; 19.P.154.169; 19.P.154.172; 19.P.154.175; 19.P.154.240; 19.P.154.244; 19.P.157.228; 19.P.157.229; 19.P.157.230; 19.P.157.231; 19.P.157.236; 19.P.157.237; 19.P.157.238; 19.P.157.239; 19.P.157.154; 19.P.157.157; 19.P.157.166; 19.P.157.169; 19.P.157.172; 19.P.157.175; 19.P.157.240; 19.P.157.244; 19.P.166.228; 19.P.166.229; 19.P.166.230; 19.P.166.231; 19.P.166.236; 19.P.166.237; 19.P.166.238; 19.P.166.239; 19.P.166.154; 19.P.166.157; 19.P.166.166; 19.P.166.169; 19.P.166.172; 19.P.166.175; 19.P.166.240; 19.P.166.244; 19.P.169.228; 19.P.169.229; 19.P.169.230; 19.P.169.231; 19.P.169.236; 19.P.169.237; 19.P.169.238; 19.P.169.239; 19.P.169.154; 19.P.169.157; 19.P.169.166; 19.P.169.169; 19.P.169.172; 19.P.169.175; 19.P.169.240; 19.P.169.244; 19.P.172.228; 19.P.172.229; 19.P.172.230; 19.P.172.231; 19.P.172.236; 19.P.172.237; 19.P.172.238; 19.P.172.239; 19.P.172.154; 19.P.172.157; 19.P.172.166; 19.P.172.169; 19.P.172.172; 19.P.172.175; 19.P.172.240; 19.P.172.244; 19.P.175.228; 19.P.175.229; 19.P.175.230; 19.P.175.231; 19.P.175.236; 19.P.175.237; 19.P.175.238; 19.P.175.239; 19.P.175.154; 19.P.175.157; 19.P.175.166; 19.P.175.169; 19.P.175.172; 19.P.175.175; 19.P.175.240; 19.P.175.244; 19.P.240.228; 19.P.240.229; 19.P.240.230; 19.P.240.231; 19.P.240.236; 19.P.240.237; 19.P.240.238; 19.P.240.239; 19.P.240.154; 19.P.240.157; 19.P.240.166; 19.P.240.169; 19.P.240.172; 19.P.240.175; 19.P.240.240; 19.P.240.244; 19.P.244.228; 19.P.244.229; 19.P.244.230; 19.P.244.231; 19.P.244.236; 19.P.244.237; 19.P.244.238; 19.P.244.239; 19.P.244.154; 19.P.244.157; 19.P.244.166; 19.P.244.169; 19.P.244.172; 19.P.244.175; 19.P.244.240; 19.P.244.244;

Prodrugs of 19.U

19.U.228.228; 19.U.228.229; 19.U.228.230; 19.U.228.231; 19.U.228.236; 19.U.228.237; 19.U.228.238; 19.U.228.239; 19.U.228.154; 19.U.228.157; 19.U.228.166; 19.U.228.169; 19.U.228.172; 19.U.228.175; 19.U.228.240; 19.U.228.244; 19.U.229.228; 19.U.229.229; 19.U.229.230; 19.U.229.231; 19.U.229.236; 19.U.229.237; 19.U.229.238; 19.U.229.239; 19.U.229.154; 19.U.229.157; 19.U.229.166; 19.U.229.169; 19.U.229.172; 19.U.229.175; 19.U.229.240; 19.U.229.244; 19.U.230.228; 19.U.230.229; 19.U.230.230; 19.U.230.231; 19.U.230.236; 19.U.230.237; 19.U.230.238; 19.U.230.239; 19.U.230.154; 19.U.230.157; 19.U.230.166; 19.U.230.169; 19.U.230.172; 19.U.230.175; 19.U.230.240; 19.U.230.244; 19.U.231.228; 19.U.231.229; 19.U.231.230; 19.U.231.231; 19.U.231.236; 19.U.231.237; 19.U.231.238; 19.U.231.239; 19.U.231.154; 19.U.231.157; 19.U.231.166; 19.U.231.169; 19.U.231.172; 19.U.231.175; 19.U.231.240; 19.U.231.244; 19.U.236.228; 19.U.236.229; 19.U.236.230; 19.U.236.231; 19.U.236.236; 19.U.236.237; 19.U.236.238; 19.U.236.239; 19.U-236.154; 19.U.236.157; 19.U.236.166; 19.U.236.169; 19.U.236.172; 19. V.236.175; 19.U.236.240; 19.U.236.244; 19.U.237.228; 19.U.237.229; 19.U.237.230; 19.U.237.231; 19.U.237.236; 19.U.237.237; 19.U.237.238; 19.U.237.239; 19.U.237.154; 19.U.237.157; 19.U.237.166; 19.U.237.169; 19.U.237.172; 19.U.237.175; 19.U.237.240; 19.U.237.244; 19.U.238.228; 19.U.238.229; 19.U.238.230; 19.U.238.231; 19.U.238.236; 19.U.238.237; 19.U.238.238; 19.U.238.239; 19.U.238.154; 19.U.238.157; 19.U.238.166; 19.U.238.169; 19.U.238.172; 19.U.238.175; 19.U.238.240; 19.U.238.244; 19.U.239.228; 19.U.239.229; 19.U.239.230; 19.U.239.231; 19.U-239.236; 19.U.239.237; 19.U.239.238; 19.U.239.239; 19.U-239.154; 19.U.239.157; 19.U.239.166; 19.U.239.169; 19.U.239.172; 19.U.239.175; 19.U.239.240; 19.U.239.244; 19.U.154.228; 19.U.154.229; 19.U154.230; 19.U154.231; 19.U.154.236; 19 '.U.154.237; 19.U.154.238; 19.U.154.239; 19.U.154.154; 19.U.154.157; 19.U.154.166; 19.U.154.169; 19.U.154.172; 19.U.154.175; 19.U.154.240; 19.U.154.244; 19.U.157.228; 19.U.157.229; 19.U.157.230; 19.U.157.231; 19.U.157.236; 19.U.157.237; 19.U.157.238; 19 '.U..157. ,239; 19.U.157.154; 19.U.157.157; 19.U.157.166; 19 '.U..157.169; 19.U.157.172; 19.U.157.175; 19.U157.24Q; 19.U.157.244; 19.U.166.228; 19.U.166.229; 19.U.166.230; 19.U.166.231; 19.U.166.236; 19.U.166.237; 19.U.166.238; 19.U.166.239; 19.U.166.154; 19.U.166.157; 19.U.166.166; 19.U.166.169; 19. ,U.166.172; 19.U.166.175; 19.U.166.240; 19.U.166.244; 19.U.169.228; 19.U.169.229; 19.U.169.230; 19.U.169.231; 19.U.169.236; 19.U.169.237; 19.U.169.238; 19.U.169.239; 19.U.169.154; 19.U.169.157; 19.U.169.166; 19.U.169.169; 19.U.169.172; 19.U.169.175; 19.U.169.240; 19.U.169.244; 19.U.172.228; 19.U.172.229; 19.U.172.230; 19.U.172.231; 19.U.172.236; 19.U.172.237; 19.U.172.238; 19.U.172.239; 19.U.172.154; 19.U.172.157; 19.U.172.166; 19.U172.169; 19.U.172172; 19.U.172.175; 19.U.172.240; 19.U.172.244; 19.U175.228; 19.U175.229; 19.U.175.230; 19.U.175.231; 19.U.175.236; 19.U175.237; 19.U.175.238; 19.U175.239; 19.U.175.154; 19.U175157; 19.U175.166; 19.U.175169; 19 '.U..175.172; 19.U175.175; 19.U.175.240; 19.U175.244; 19.U.240.228; 19.U.240.229; 19.U.240.230; 19.U.240.231; 19.U.240.236; 19.U.240.237; 19.U.240.238; 19.U.240.239; 19.U.240.154; 19.U.240.157; 19.U.240.166; 19.U.240169; 19.U.240.172; 19.U.240175; 19.U.240.240; 19.U.240.244; 19.U.244.228; 19.U.244.229; 19.U.244.230; 19.U.244.231; 19.U.244.236; 19.U.244.237; 19.U.244.238; 19.U.244.239; 19.U.244.154; 19.U.244157; 19.U.244.166; 19.U.244.169; 19.U.244.172; 19.U.244.175; 19.U.244.240; 19.U.244.244;

Prodrugs of 19.CD

19.CD.228.228; 19.CD.228.229; 19.CD.228.230; 19.CD.228.231; 19.CD.228.236; 19.CD.228.237; 19.CD.228.238; 19.CD.228.239; 19.CD.228.154; 19.CD.228.157; 19.CD.228.166; 19.CD.228169; 19.CD.228.172; 19.CD.228175; 19.CD.228.240; 19.CD.228.244; 19.CD.229.228; 19.CD.229.229; 19.CD.229.230; 19.CD.229.231; 19.CD.229.236; 19.CD.229.237; 19.CD.229.238; 19.CD.229.239; 19.CD.229.154; 19. CD.229.157; 19.CD.229.166; 19. CD 229.169; 19.CD.229.172; 19.CD.229.175; 19. CD.229.2m,- 19.CD.229.244; 19.CD.230.228; 19.CD.230.229; 19.CD.230.230; 19.CD.230.231; 19.CD.230.236; 19.CD.230.237; 19.CD.230.238; 19.CD.230.239; 19.CD.230.154; 19.CD.230.157; 19.CD.230.166; 19.CD.230.169; 19.CD.230.172; 19.CD.230.175; 19.CD.230.240; 19.CD.230.244; 19.CD.231.228; 19.CD.231.229; 19.CD.231.230; 19.CD.231.231; 19.CD.231.236; 19.CD.231.237; 19.CD.231.238; 19.CD.231.239; 19.CD.231.154; 19.CD.231.157; 19.CD.231.166; 19.CD.231.169; 19. CD.231.172; 19.CD.231.175; 19.CD.231.240; 19.CD.231.244; 19.CD.236.228; 19.CD.236.229; 19.CD.236.230; 19.CD.236.231; 19. CD.236.236; 19. CD.236.237; 19.CD.236.238; 19.CD.236.239; 19.CD.236.154; 19.CD.236.157; 19. CD.236.166; 19.CD.236.169; 19. CD.236.172; 19.CD.236.175; 19.CD.236.240; 19.CD.236.244; 19.CD.237.228; 19.CD.237.229; 19.CD.237.230; 19.CD.237.231; 19.CD.237.236; 19.CD.237.237; 19.CD.237.238; 19.CD.237.239; 19.CD.237.154; 19.CD.237.157; 19.CD.237.166; 19. CD.237.169; 19. CD.237.172; 19. CD..237.175; 19.CD.237.240; 19.CD.237.244; 19.CD.238.228; 19.CD.238.229; 19.CD.238.230; 19.CD.238.231; 19.CD.238.236; 19.CD.238.237; 19.CD.238.238; 19.CD.238-239; 19.CD.238.154; 19.CD.238.157; 19.CD.238.166; 19.CD.238.169; 19.CD.238.172; 19.CD.238.175; 19.CD.238.240; 19.CD.238.244; 19.CD.239.228; 19.CD.239.229; 19.CD.239.230; 19.CD.239.231; 19.CD.239.236; 19. CD.239.237; 19.CD.239.238; 19.CD.239.239; 19.CD.239.154; 19.CD.239.157; 19.CD.239.166; 19.CD.239.169; 19.CD.239.172; 19. CD.239.175; 19.CD.239.24Q; 19.CD.239.244; 19.CD.154.228; 19.CD.154.229; 19.CD.154.230; 19.CD.154.231; 19.CD.154.236; 19.CD.154.237; 19.CD.154.238; 19.CD.154.239; 19.CD.154.154; 19.CD.154.157; 19.CD.154.166; 19.CD.154.169; 19.CD.154.172; 19.CD.154.175; 19.CD.154.24Q; 19.CD.154.244; 19.CD.157.228; 19. CD.157.229; 19.CD.157.230; 19.CD.157.231; 19. CD.157.236; 19.CD.157.237; 19.CD.157.238; 19.CD.157.239; 19.CP.157.154; 19.CD.157.157; 19.CD.157.166; 19.CD.157.169; 19.CD.157.172; 19.CD.157.175; 19.CD.157.240; 19.CD.157.244; 19.CD.166.228; 19.CD.166.229; 19.CD.166.230; 19.CD.166.231; 19.CD.166.236; 19.CD.166.237; 19.CD.166.238; 19.CD.166.239; 19.CD.166.154; 19.CD.166.157; 19.CD.166.166; 19.CD.166.169; 19. CD.166.172; 19.CD.166.175; 19.CD.166.240; 19.CD.166.244; 19.CD.169.228; 19.CD.169.229; 19.CD.169.230; 19.CD.169.231; 19.CD.169.236; 19.CD.169.237; 19.CD.169.238; 19.CD.169.239; 19.CD.169.154; 19.CD.169.157; 19.CD.169.166; 19.CD.169.169; 19. CD.169.172; 19.CD.169.175; 19.CD.169.240; 19.CD.169.244; 19.CD.172.228; 19.CD.172.229; 19.CD.172.230; 19. CD.172.231; 19. CD.172.236; 19. CD.172.237; 19.CD.172.238; 19.CD.172.239; 19.CD.172.154; 19.CD.172.157; 19.CD.172.166; 19. CD.172.169; 19. CD.172.172; 19. CD.172.175; 19.CD.172.240; 19.CD.172.244; 19.CD.175.228; 19. CD.175.229; 19.CD.175.230; 19.CD.175.231; 19.CD.175.236; 19.CD.175.237; 19. CD.175.238; 19.CD.175.239; 19.CD.175.154; 19.CD.175.157; 19.CD.175.166; 19.CD.175.169; 19. CD.175.172; 19.CD.175.175; 19.CD.175.240; 19.CD.175.244; 19.CD.240.228; 19.CD.240.229; 19.CD.240.230; 19.CD.240.231; 19.CD.240.236; 19.CD.240.237; 19.CD.240.238; 19.CD.240.239; 19.CD.240.154; 19.CD.240.157; 19.CD.240.166; 19.CD.240.169; 19.CD.240.172; 19.CD.240.175; 19.CD.240.240; 19.CD.240.244; 19.CD.244.228; 19.CD.244.229; 19.CD.244.230; 19.CD.244.231; 19.CD.244.236; 19.CD.244.237; 19.CD.244.238; 19.CD.244.239; 19.CD.244.154; 19.CD.244.157; 19.CD.244.166; 19.CD.244.169; 19.CD.244.172; 19.CD.244.175; 19.CD.244.240; 19.CD.244.244;

Prodrugs of 19.EB

19.EB.228.228; 19.EB.228.229; 19.EB.228.230; 19.EB.228.231; 19.EB.228.236; 19.EB.228.237; 19.EB.228.238; 19.EB.228.239; 19.EB.228.154; 19.EB.228.157; 19.EB.228.166; 19.EB.228.169; 19.EB.228.172; 19.EB.228.175; 19.EB.228.240; 19.EB.228.244; 19.EB.229.228; 19.EB.229.229; 19.EB.229.230; 19.EB.229.231; 19.EB.229.236; 19.EB.229.237; 19.EB.229.238; 19.EB.229.239; 19.EB.229.154; 19.EB.229.157; 19.EB.229.166; 19.EB.229.169; 19.EB.229.172; 19.EB.229.175; 19.EB.229.240; 19.EB.229.244; 19.EB.230.228; 19.EB.230.229; 19.EB.230.230; 19.EB.230.231; 19.EB.230.236; 19.EB.230.237; 19.EB.230.238; 19.EB.230.239; 19.EB.23Q.154; 19.EB.230.157; 19.EB.230.166; 19.EB.230.169; 19.EB.230.172; 19.EB.230.175; 19.EB.230.240; 19.EB.230.244; 19.EB.231.228; 19.EB.231.229; 19.EB.231.230; 19.EB.231.231; 19.EB.231.236; 19.EB.231.237; 19.EB.231.238; 19.EB.231.239; 19.EB.231.154; 19.EB.231.157; 19.EB.231.166; 19.EB.231.169; 19.EB.231.172; 19.EB.231.175; 19.EB.231.240; 19.EB.231.244; 19.EB.236.228; 19.EB.236.229; 19.EB.236.230; 19.EB.236.231; 19.EB.236.236; 19.EB.236.237; 19.EB.236.238; 19.EB.236.239; 19.EB.236.154; 19.EB.236.157; 19.EB.236.166; 19.EB.236.169; 19.EB.236.172; 19.EB.236.175; 19.EB.236.240; 19.EB.236.244; 19.EB.237.228; 19.EB.237.229; 19.EB.237.230; 19.EB.237.231; 19.EB.237.236; 19.EB.237.237; 19.EB.237.238; 19.EB.237.239; 19.EB.237.154; 19.EB.237.157; 19.EB.237.166; 19.EB.237.169; 19.EB.237.172; 19. EB.237.175; 19.EB.237.240; 19.EB.237.244; 19.EB.238.228; 19.EB.238.229; 19.EB.238.230; 19.EB.238.231; 19.EB.238.236; 19.EB.238.237; 19.EB.238.238; 19.EB.238.239; 19.EB.238.154; 19.EB.238.157; 19.EB.238.166; 19.EB.238.169; 19.EB.238.172; 19.EB.238.175; 19.EB.238.240; 19.EB.238.244; 19.EB.239.228; 19.EB.239.229; 19.EB.239.230; 19.EB.239.231; 19.EB.239.236; 19.EB.239.237; 19.EB.239.238; 19.EB.239.239; 19.EB.239.154; 19. EB .239.157; 19.EB.239.166; 19.EB.239.169; 19.EB.239.172; 19.EB.239.175; 19.EB.239.240; 19.EB.239.244; 19.EB.154.228; 19.EB.154.229; 19.EB.154.230; 19.EB.154.231; 19.EB.154.236; 19.EB.154.237; 19.EB.154.238; 19.EB.154.239; 19.EB.154.154; 19.EB.154.157; 19.EB.154.166; 19.EB.154.169; 19.EB.154.172; 19.EB.154.175; 19.EB.154.240; 19.EB.154.244; 19.EB.157.228; 19.EB.157.229; 19.EB.157.230; 19.EB.157.231; 19.EB.157.236; 19.EB.157.237; 19.EB.157.238; 19. ΕB.157.239; 19.EB.157.154; 19.EB.157.157; 19.EB.157.166; 19.EB.157.169; 19. ΕQ.157.172; 19.EB.157.175; 19.EB.157.240; 19.EB.157.244; 19.EB.166.228; 19.EB.166.229; 19.EB.166.230; 19.EB.166.231; 19.EB.166.236; 19.EB.166.237; 19.EB.166.238; 19.EB.166.239; 19.EB.166.154; 19.EB.166.157; 19.EB.166.166; 19.EB.166.169; 19.EB.166.172; 19.EB.166.175; 19.EB.166.240; 19.EB.166.244; 19.EB.169.228; 19.EB.169.229; 19.EB.169.230; 19.EB.169.231; 19.EB.169.236; 19.EB.169.237; 19.EB.169.238; 19.EB.169.239; 19.EB.169.154; 19.EB.169.157; 19.EB.169.166; 19.EB.169.169; 19.EB.169.172; 19.EB.169.175; 19.EB.169.240; 19.EB.169.244; 19.EB.172.228; 19.EB.172.229; 19.EB.172.230; 19.EB.172.231; 19.EB.172.236; 19. Ε&.172.237; 19.EB.172.238; 19.EB.172.239; 19.EB.172.154; 19.EB.172.157; 19.EB.172.166; 19.EB.172.169; 19.EB.172.172; 19.EB.172.175; 19.EB.172.240; 19.EB.172.244; 19.EB.175.228; 19.EB.175.229; 19.EB.175.230; 19.EB.175.231; 19.EB.175.236; 19.EB.175.237; 19.EB.175.238; 19.EB.175.239; 19.EB.175.154; 19.EB.175.157; 19.EB.175.166; 19.EB.175.169; 19.EB.175.172; 19.EB.175.175; 19.EB.175.240; 19.EB.175.244; 19.EB.240.228; 19.EB.240.229; 19.EB.240.230; 19.EB.240.231; 19.EB.240.236; 19.EB.240.237; 19.EB.240.238; 19.EB.240.239; 19.EB.240.154; 19.EB.240.157; 19.EB.240.166; 19.EB.240.169; 19.EB.240.172; 19.EB.240.175; 19.EB.240.240; 19.EB.240.244; 19.EB.244.228; 19.EB.244.229; 19.EB.244.230; 19.EB.244.231; 19.EB.244.236; 19.EB.244.237; 19.EB.244.238; 19.EB.244.239; 19.EB.244.154; 19.EB.244.157; 19.EB.244.166; 19.EB.244.169; 19.EB.244.172; 19.EB.244.175; 19.EB.244.24Q; 19.EB.244.244;

Prodrugs of 20.B

20.B.228.228; 20.B.228.229; 20.B.228.230; 20.B.228.231; 20.B.228.236; 20.B.228.237; 20.B.228.238; 20.B.228.239; 20.B.228.154; 20.B.228.157; 20.B.228.166; 20.B.228.169; 20.B.228.172; 20.B.228.175; 20.B.228.240; 20.B.228.244; 20.B.229.228; 20.B.229.229; 20.B.229.230; 20.B.229.231; 2Q.B.229.236; 20.B.229.237; 20.B.229.238; 2Q.B.229.239; 20.B.229.154; 20.B.229.157; 20.B.229.166; 20.B.229.169; 20.B.229.172; 20.B.229.175; 20.B.229.240; 20.B.229.244; 20.B.230.228; 20.B.230.229; 20.B.230.230; 20.B.230.231; 20.B.230.236; 2Q.B.230.237; 20.B.230.238; 20.B.230.239; 20.B.230.154; 20.B.230.157; 20.B.230.166; 20.B.230.169; 20.B.230.172; 20.B.230.175; 20.B.230.240; 20.B.230.244; 20.B.231.228; 20.B.231.229; 20.B.231.230; 20.B.231.231; 20.B.231.236; 20.B.231.237; 20.B.231.238; 20.B.231.239; 20.B.231.154; 20.B.231.157; 20.B.231.166; 20.B.231.169; 20.B.231.172; 20.B.231.175; 20.B.231.240; 2Q.B.231.244; 20.B.236.228; 20.B.236.229; 20.B.236.230; 20.B.236.231; 20.B.236.236; 20.B.236.237; 20.B.236.238; 20.B.236.239; 20.B.236.154; 20.B.236.157; 20.B.236.166; 20.B.236.169; 20.B.236.172; 20.B.236.175; 2Q.B.236.24Q; 20.B.236.244; 20.B.237.228; 2Q.B.237.229; 20.B.237.230; 20.B.237.231; 20.B.237.236; 20.B.237.237; 20.B.237.238; 20.B.237.239; 20.B.237.154; 20.B.237.157; 2Q.B.237.166; 20.B.237.169; 20.B.237.172; 20.B.237.175; 20.B.237.240; 20.B.237.244; 20.B.238.228; 20.B.238.229; 20.B.238.230; 20.B.238.231; 20.B.238.236; 20.B.238.237; 20.B.238.238; 20.B.238.239; 20-B.238.154; 20.B.238.157; 20.B.238.166; 20.B.238.169; 2Q.B.238.172; 20.B.238.175; 20.B.238.240; 20.B.238.244; 20.B.239.228; 20.B.239.229; 20.B.239.230; 20.B.239.231; 20.B.239.236; 20.B.239.237; 20.B.239.238; 20.B.239.239; 20.B.239.154; 20.B.239.157; 20.B.239.166; 20.B.239.169; 20.B.239.172; 20.B.239.175; 20.B.239.240; 2Q.B.239.244; 20.B.154.228; 20.B.154.229; 20.B.154.230; 20.B.154.231; 20.B.154.236; 20.B.154.237; 20.B.154.238; 20.B.154.239; 20.B.154.154; 20.B.154.157; 20.B.154.166; 20.B.154.169; 20.B.154.172; 20.B.154.175; 20.B.154.240; 20.B.154.244; 20.B.157.228; 20.B.157.229; 20.B.157.230; 20.B.157.231; 20.B.157.236; 20.B.157.237; 20.B.157.238; 20.B.157.239; 20.B.157.154; 20.B.157.157; 20.B.157.166; 20.B.157.169; 20.B.157.172; 20.B.157.175; 20.B.157.240; 20.B.157.244; 20.B.166.228; 20.B.166.229; 20.B.166.230; 20.B.166.231; 20.B.166.236; 20.B.166.237; 20.B.166.238; 20.B.166.239; 20.B.166.154; 20.B.166.157; 20.B.166.166; 20.B.166.169; 20.B.166.172; 20.B.166.175; 2Q.B.166.240; 20.B.166.244; 20.B.169.228; 20.B.169.229; 20.B.169.230; 20.B.169.231; 20.B.169.236; 20.B.169.237; 20.B.169.238; 20.B.169.239; 20.B.169.154; 20.B.169.157; 20.B.169.166; 20.B.169.169; 20.B.169.172; 20.B.169.175; 20.B.169.240; 20.B.169.244; 20.B.172.228; 20.B.172.229; 20.B.172.230; 20.B.172.231; 20.B.172.236; 20.B.172.237; 20.B.172.238; 20.B.172.239; 20.B.172.154; 20.B.172.157; 20.B.172.166; 20.B.172.169; 20.B.172.172; 20.B.172.175; 20.B.172.240; 20.B.172.244; 20.B.175.228; 20.B.175.229; 20.B.175.230; 20.B.175.231; 20.B.175.236; 20.B.175.237; 20.B.175.238; 20.B.175.239; 20.B.175.154; 20.B.175.157; 20.B.175.166; 20.B.175.169; 20.B.175.172; 20.B.175.175; 20.B.175.240; 20.B.175.244; 20.B.240.228; 20.B.240.229; 20.B.240.230; 20.B.240.231; 20.B.240.236; 20.B.240.237; 20.B.240.238; 20.B.240.239; 20.B.240.154; 20.B.240.157; 20.B.240.166; 20.B.240.169; 20.B.240.172; 20.B.240.175; 20.B.240.240; 20.B.240.244; 20.B.244.228; 20.B.244.229; 20.B.244.230; 20.B.244.231; 20.B.244.236; 20.B.244.237; 20.B.244.238; 20.B.244.239; 20.B.244.154; 20.B.244.157; 20.B.244.166; 2Q.B.244.169; 20.B.244.172; 20.B.244.175; 2Q.B.244.240; 20.B.244.244;

Prodrugs of 20.D

20.D.228.228; 20.D.228.229; 20.D.228.230; 20.D.228.231; 20.D.228.236; 20.D.228.237; 20.D.228.238; 20.D.228.239; 20.D.228.154; 20.D.228.157; 20.D.228.166; 20.D.228.169; 20.D.228.172; 20.D.228.175; 20.D.228.240; 20.D.228.244; 20.D.229.228; 20.D.229.229; 20.D.229.230; 20.D.229.231; 20.D.229.236; 20.D.229.237; 20.D.229.238; 20.D.229.239; 20.D.229.154; 20.D.229.157; 20.D.229.166; 20.D.229.169; 20.D.229.172; 20.D.229.175; 20.D.229.240; 20.D.229.244; 20.D.230.228; 20.D.230.229; 20.D.230.230; 20.D.230.231; 20.D.230.236; 20.D.230.237; 20.D.230.238; 20.D.23Q.239; 20.D.230.154; 20.D.230.157; 20.D.230.166; 2Q.D.230.169; 20.D.230.172; 20.D.230.175; 20.D.230.240; 20.D.230.244; 20.D.231.228; 20.D.231.229; 20.D.231.230; 20.D.231.231; 20.D.231.236; 20.D.231.237; 20.D.231.238; 20.D.231.239; 20.D.231.154; 20.D.231.157; 20.D.231.166; 20.D.231.169; 20.D.231.172; 20.D.231.175; 20.D.231.240; 20.D.231.244; 20.D.236.228; 20.D.236.229; 20.D.236.230; 20.D.236.231; 20.D.236.236; 20.D.236.237; 20.D.236.238; 20.D.236.239; 2Q.D.236.154; 20.D.236.157; 20.D.236.166; 20.D.236.169; 20.D.236.172; 20.D.236.175; 20.D.236.240; 20.D.236.244; 20.D.237.228; 20.D.237.229; 20.D.237.230; 2Q.D.237.231; 20.D.237.236; 20.D.237.237; 20.D.237.238; 20.D.237.239; 20.D.237.154; 20.D.237.157; 20.D.237.166; 20.D.237.169; 20.D.237.172; 20.D.237.175; 20.D.237.240; 20.D.237.244; 20.D.238.228; 2Q.D.238.229; 20.D.238.230; 20.D.238.231; 20.D.238.236; 2Q.D.238.237; 20.D.238.238; 20.D.238.239; 20.D.238.154; 20.D.238.157; 20.D.238.166; 20.D.238.169; 20.D.238.172; 20.D.238.175; 20.D.238.240; 20.D.238.244; 20.D.239.228; 20.D.239.229; 20.D.239.230; 20.D.239.231; 20.D.239.236; 20.D.239.237; 20.D.239.238; 20.D.239.239; 20.D.239.154; 20.D.239.157; 20.D.239.166; 20.D.239.169; 20.D.239.172; 20.D.239.175; 20.D.239.240; 20.D.239.244; 20.D.154.228; 20.D.154.229; 20.D.154.230; 20.D.154.231; 20.D.154.236; 20.D.154.237; 20.D.154.238; 20.D.154.239; 20.D.154.154; 20.D.154.157; 20.D.154.166; 20.D.154.169; 20.D.154.172; 20.D.154.175; 20.D.154.24Q; 20.D.154.244; 20.D.157.228; 20.D.157.229; 20.D.157.230; 20.D.157.231; 20.D.157.236; 20.D.157.237; 20.D.157.238; 20.D.157.239; 20.D.157.154; 20.D.157.157; 20.D.157.166; 20.D.157.169; 20.D.157.172; 20.D.157.175; 20.D.157.240; 20.D.157.244; 20.D.166.228; 20.D.166.229; 20.D.166.230; 20.D.166.231; 20.D.166.236; 20.D.166.237; 20.D.166.238; 20.D.166.239; 20.D.166.154; 20.D.166.157; 20.D.166.166; 20.D.166.169; 20.D.166.172; 20.D.166.175; 20.D.166.240; 20.D.166.244; 20.D.169.228; 20.D.169.229; 20.D.169.230; 20.D.169.231; 20.D.169.236; 20.D.169.237; 20.D.169.238; 20.D.169.239; 20.D.169.154; 20.D.169.157; 20.D.169.166; 2Q.D.169.169; 20.D.169.172; 20.D.169.175; 20.D.169.240; 20.D.169.244; 20.D.172.228; 20.D.172.229; 20.D.172.230; 20.D.172.231; 20.D.172.236; 2Q.D.172.237; 20.D.172.238; 20.D.172.239; 20.D.172.154; 20.D.172.157; 20.D.172.166; 20.D.172.169; 20.D.172.172; 20.D.172.175; 20.D.172.240; 20.D.172.244; 20.D.175.228; 20.D.175.229; 20.D.175.230; 20.D.175.231; 20.D.175.236; 20.D.175.237; 20.D.175.238; 20.D.175.239; 20.D.175.154; 20.D.175.157; 20.D.175.166; 20.D.175.169; 20.D.175.172; 20.D.175.175; 20.D.175.240; 2Q.D.175.244; 20.D.240.228; 20.D.240.229; 20.D.240.230; 2Q.D.240.231; 20.D.240.236; 20.D.240.237; 20.D.240.238; 20.D.240.239; 20.D.240.154; 20.D.240.157; 20.D.240.166; 20.D.240.169; 20.D.240.172; 20.U240.175; 2Q.D.240.240; 20.D.240.244; 20.D.244.228; 20.D.244.229; 20.D.244.230; 20.D.244.231; 20.D.244.236; 20.D.244.237; 20.D.244.238; 20.D.244.239; 20.D.244.154; 20.D.244.157; 20.D.244.166; 20.D.244.169; 20.D.244.172; 20.D.244.175; 20.D.244.240; 20.D.244.244;

Prodrugs of 20.AB

20.AB.228.228; 20.AB.228.229; 20.AB.228.230; 20.AB.228.231; 20.AB.228.236; 20.AB.228.237; 20.AB.228.238; 20.AB.228.239; 20.AB.228.154; 20. AB.228.157; 20.AB.228.166; 20.AB.228.169; 20.AB.228.172; 20.AB.228.175; 20.AB.228.240; 20.AB.228.244; 20.AB.229.228; 20.AB.229.229; 20.AB.229.230; 20.AB.229.231; 20.AB.229.236; 20.AB.229.237; 20.AB.229.238; 20. AB.229.239; 20.AB.229.154; 20.AB.229.157; 20.AB.229.166; 20.AB.229.169; 20.AB.229.172; 20.AB.229.175; 20.AB.229.240; 20.AB.229.244; 20.AB.230.228; 20.AB.230.229; 20.AB.230.230; 20.AB.230.231; 20.AB.230.236; 20.AB.230.237; 20.AB.230.238; 20.AB.230.239; 20.AB.230.154; 20.AB.230.157; 20.AB.230.166; 20.AB.230.169; 20.AB.230.172; 20.AB.230.175; 20.AB.230.240; 20.AB.230.244; 20.AB.231.228; 20.AB.231.229; 20.AB.231.230; 20.AB.231.231; 20.AB.231.236; 20.AB.231.237; 20.AB.231.238; 20.AB.231.239; 20.AB.231.154; 20.AB.231.157; 20.AB.231.166; 20- AB.231.169; 20.AB.231.172; 20.AB.231.175; 2Q.AB.231.240; 20.AB.231.244; 20.AB.236.228; 20.AB.236.229; 20.AB.236.230; 20. AB.236.231; 20.AB.236.236; 20.AB.236.237; 20.AB.236.238; 20.AB.236.239; 20.AB.236.154; 20.AB.236.157; 20.AB.236.166; 20.AB.236.169; 20.AB.236.172; 20.AB.236.175; 20.AB.236.240; 20.AB.236.244; 20.AB.237.228; 20.AB.237.229; 20.AB.237.230; 20.AB.237.231; 20.AB.237.236; 20.AB.237.237; 20.AB.237.238; 20. AB.237.239; 20.AB.237.154; 20.AB.237.157; 20.AB.237.166; 20.AB.237.169; 20.AB.237.172; 20.AB.237.175; 20.AB.237.240; 20.AB.237.244; 20.AB.238.228; 20.AB.238.229; 20.AB.238.230; 20.AB.238.231; 20.AB.238.236; 20.AB.238.237; 20.AB.238.238; 20.AB.238.239; 20.AB.238.154; 20.AB.238.157; 20.AB.238.166; 20.AB.238.169; 20.AB.238.172; 20.AB.238.175; 20.AB.238.240; 20.AB.238.244; 20.AB.239.228; 20.AB.239.229; 20.AB.239.230; 20.AB.239.231; 2Q.AB.239.236; 20.AB.239.237; 20.AB.239.238; 20.AB.239.239; 20.AB.239.154; 20.AB.239.157; 20.AB.239.166; 20.AB.239.169; 20.AB.239.172; 20.AB.239.175; 20.AB.239.240; 20.AB.239.244; 20.AB.154.228; 20.AB.154.229; 20.AB.154.230; 20.AB.154.231; 20.AB.154.236; 20.AB.154.237; 20.AB.154.238; 20.AB.154.239; 20.AB.154.154; 20.AB.154.157; 20.AB.154.166; 20.AB.154.169; 20.AB.154.172; 20.AB.154.175; 20.AB.154.240; 20.AB.154.244; 20.AB.157.228; 20.AB.157.229; 20.AB.157.230; 20.AB.157.231; 20.AB.157.236; 20.AB.157.237; 20.AB.157.238; 20.AB.157.239; 20.AB.157.154; 20.AB.157.157; 20.AB.157.166; 20.AB.157.169; 20.AB.157.172; 20.AB.157.175; 20.AB.157.240; 20.AB.157.244; 20.AB.166.228; 20.AB.166.229; 20.AB.166.23Q; 20.AB.166.231; 20.AB.166.236; 20.AB.166.237; 20.AB.166.238; 20.AB.166.239; 2Q.AB.166.154; 2Q.AB.166.157; 20.AB.166.166; 20.AB.166.169; 20.AB.166.172; 2Q.AB.166.175; 20.AB.166.240; 20.AB.166.244; 20.AB.169.228; 20.AB.169.229; 20.AB.169.230; 20.AB.169.231; 20.AB.169.236; 20.AB.169.237; 20.AB.169.238; 20.AB.169.239; 20.AB.169.154; 20.AB.169.157; 20.AB.169.166; 2Q.AB.169.169; 20.AB.169.172; 20.AB.169.175; 20.AB.169.240; 20.AB.169.244; 20. AB.172.228; 20.AB.172.229; 20.AB.172.23Q; 20.AB.172.231; 20.AB.172.236; 20.AB.172.237; 20.AB.172.238; 20.AB.172.239; 20.AB.172.154; 20.AB.172.157; 20.AB.172.166; 2Q.AB.172.169; 20.AB.172.172; 20.AB.172.175; 20.AB.172.240; 20.AB.172.244; 2Q.AB.175.228; 20.AB.175.229; 20.AB.175.230; 20.AB.175.231; 20.AB.175.236; 20.AB.175.237; 20.AB.175.238; 20.AB.175.239; 20.AB.175.154; 20.AB.175.157; 20.AB.175.166; 20.AB.175.169; 20.AB.175.172; 20.AB.175.175; 20.AB.175.240; 20.AB.175.244; 20.AB.240.228; 20.AB.240.229; 20.AB.240.230; 20.AB.240.231; 20.AB.240.236; 20.AB.240.237; 20.AB.240.238; 20.AB.240.239; 20.AB.240.154; 20.AB.240.157; 20.AB.240.166; 20.AB.240.169; 20.AB.240.172; 20.AB.240.175; 20.AB.240.240; 2Q.AB.24Q.244; 20.AB.244.228; 20.AB.244.229; 20.AB.244.230; 20.AB.244.231; 20.AB.244.236; 20.AB.244.237; 2Q.AB.244.238; 20.AB.244.239; 20.AB.244.154; 20.AB.244.157; 20.AB.244.166; 20.AB.244.169; 20.AB.244.172; 20.AB.244.175; 20. AB.244.240; 20.AB.244.244;

Prodrugs of 20.BI

20.BI.228.228; 20.BI.228.229; 20.BI.228.230; 20.BI.228.231; 20.BI.228.236; 20.BI.228.237; 20.BI.228.238; 20.BI.228.239; 20.BI.228.154; 20.BI.228.157; 20.BI.228.166; 20.BI.228.169; 20.BI.228.172; 20.BI.228.175; 20.BI.228.240; 20.BI.228.244; 20.BI.229.228; 20.BI.229.229; 20.BI.229.230; 20.BI.229.231; 20.BI.229.236; 20.BI.229.237; 20.BI.229.238; 20.BI.229.239; 20.BI.229.154; 20.BI.229.157; 20.BI.229.166; 20.BI.229.169; 20.BI.229.172; 20.BI.229.175; 20.BI.229.240; 20.BI.229.244; 20.BI.230.228; 20.BI.230.229; 20.BI.230.230; 20.BI.230.231; 20.BI.230.236; 20.BI.230.237; 20.BI.230.238; 20.BI.230.239; 20.BI.230.154; 20.BI.230.157; 20.BI.230.166; 20.BI.230.169; 20.BI.230.172; 20.BI.230.175; 20.BI.230.240; 20.BI.230.244; 20.BI.231.228; 20.BI.231.229; 20.BI.231.230; 20.BI.231.231; 20.BI.231.236; 2Q.BI.231.237; 20.BI.231.238; 20.BI.231.239; 20.BI.231.154; 20.BI.231.157; 20.BI.231.166; 20.BI.231.169; 20.BI.231.172; 20.BI.231.175; 20.BI.231.240; 20.BI.231.244; 20.BI.236.228; 20.BI.236.229; 20.BI.236.230; 20.BI.236.231; 20.BI.236.236; 20.BI.236.237; 20.BI.236.238; 20.BI.236.239; 20.BI.236.154; 20.BI.236.157; 20.BI.236.166; 20.BI.236.169; 20.BI.236.172; 20.BI.236.175; 20.BI.236.240; 20.BI.236.244; 20.BI.237.228; 20.BI.237.229; 20.BI.237.230; 20.BI.237.231; 20.BI.237.236; 20.BI.237.237; 20.BI.237.238; 20.BI.237.239; 20.BI.237.154; 20.BI.237.157; 20.BI.237.166; 20.BI.237.169; 20.BL237.172; 20.BI.237.175; 20.BI.237.240; 20.BI.237.244; 20.BI.238.228; 20.BI.238.229; 20.BI.238.230; 20.BI.238.231; 20.BI.238.236; 20.BI.238.237; 20.BI.238.238; 20.BI.238.239; 20.BI.238.154; 20.BI.238.157; 20.BI.238.166; 20.BI.238.169; 20.BI.238.172; 20.BI.238.175; 20.BI.238.240; 20.BI.238.244; 20.BI.239.228; 20.BI.239.229; 20.BI.239.230; 20.BI.239.231; 20.BI.239.236; 20.BI.239.237; 20.BI.239.238; 20.BI.239.239; 20.BI.239.154; 20.BI.239.157; 20.BI.239.166; 20.BI.239.169; 20.BI.239.172; 20.BI.239.175; 20.BI.239.240; 20.BI.239.244; 20.BI.154.228; 20.BI.154.229; 20.BI.154.230; 20.BI.154.231; 20.BI.154.236; 20.BI.154.237; 20.BI.154.238; 20.BI.154.239; 20.BI.154.154; 20.BI.154.157; 20.BI.154.166; 20.BI.154.169; 20.BL154.172; 20.BI.154.175; 20.BI.154.240; 20.BI.154.244; 20.BI.157.228; 20.BI.157.229; 20.BI.157.230; 20.BI.157.231; 20.BI.157.236; 20.BI.157.237; 20.BL157.238; 20.BI.157.239; 20.BI.157.154; 20.BI.157.157; 20.BI.157.166; 20.BI.157.169; 20.BI.157.172; 20.BI.157.175; 20.BI.157.240; 20.BI.157.244; 20.BI.166.228; 20.BI.166.229; 20.BI.166.230; 20.BL166.231; 20.BI.166.236; 20.BI.166.237; 20.BI.166.238; 20.BI.166.239; 20.BI.166.154; 20.BI.166.157; 20.BI.166.166; 20.BI.166.169; 20.BI.166.172; 20.BL166.175; 20.BI.166.240; 20.BI.166.244; 20.BI.169.228; 20-BI.169.229; 20.BI.169.230; 20.BI.169.231; 20.BI.169.236; 20.BI.169.237; 20.BI.169.238; 20.BI.169.239; 20.BI.169.154; 20.BI.169.157; 20.BI.169.166; 20.BI.169.169; 20.BI.169.172; 20.BI.169.175; 20.BI.169.240; 20.BI.169.244; 20.BI.172.228; 20.BI.172.229; 20.BI.172.230; 20.BI.172.231; 20.BI.172.236; 20.BI.172.237; 20.BI.172.238; 20.BI.172.239; 20.BI.172.154; 20.BI.172.157; 20.BI.172.166; 20.BI.172.169; 20.BI.172.172; 20.BI.172.175; 20.BI.172.240; 20.BI.172.244; 20.BI.175.228; 20.BI.175.229; 20.BI.175.230; 20.BI.175.231; 20.BI.175.236; 20.BI.175.237; 20.BI.175.238; 20.BI.175.239; 20.BI.175.154; 20.BI.175.157; 20.BI.175.166; 20. BI.175.169; 20.BI.175.172; 20.BI.175.175; 20.BI.175.240; 20.BI.175.244; 20.BI.240.228; 20.BI.240.229; 20.BI.240.230; 20.BI.240.231; 20.BI.240.236; 20.BI.240.237; 20.BI.240.238; 20.BI.240.239; 20.BI.240.154; 20.BI.24Q.157; 20.BL240.166; 20.BI.240.169; 20.BI.240.172; 20.BI.240.175; 20.BI.240.240; 20.BI.240.244; 20.BI.244.228; 20.BI.244.229; 20.BI.244.230; 20.BI.244.231; 20.BI.244.236; 20.BI.244.237; 20.BI.244.238; 20.BI.244.239; 20.BI.244.154; 20.BI.244.157; 20.BI.244.166; 20.BI.244.169; 20.BI.244.172; 20.BI.244.175; 20.BI.244.240; 20.BI.244.244;

Prodrugs of 20.1

20.1.228.228; 20.1.228.229; 20.1.228.230; 20.1.228.231; 20.1.228.236; 20.1.228.237; 20.1.228.238; 20.1.228.239; 20.1.228.154; 20.1.228.157; 20.1.228.166; 20.1.228.169; 20.1.228.172; 20.1.228.175; 20.1.228.240; 20.1.228.244; 20.1.229.228; 20.1.229.229; 20.1.229.230; 20.1.229.231; 20.1.229.236; 20.1.229.237; 20.1.229.238; 20.1.229.239; 20.1.229.154; 20.1.229.157; 20.1.229.166; 20.1.229.169; 20.1.229.172; 201.229.175} 20.1.229.240; 20.1.229.244; 20.1.230.228; 20.1.230.229; 20.1.230.230; 20.1.230.231; 20.1.230.236; 20.1.230.237; 20.1.230.238; 20.1.230.239; 20.1.230.154; 20.1.230.157; 20.1.230.166; 20.1.230.169; 20.1.230.172; 20.1.230.175; 20.1.230.240; 20.1.230.244; 20.1.231.228; 20.1.231.229; 20.1.231.230; 20.1.231.231; 20.1.231.236; 20.1.231.237; 20.1.231.238; 20.1.231.239; 20.1.231.154; 20.1.231.157; 20.1.231.166; 20.1.231.169; 20.1.231.172; 20.1.231.175; 20.1.231.240; 20.1.231.244; 20.1.236.228; 20.1.236.229; 20.1.236.230; 20.1.236.231; 20.1.236.236; 20.1.236.237; 20.1.236.238; 20.1.236.239; 20.1.236.154; 20.1.236.157; 20.1.236.166; 20.1.236.169; 20.1.236.172; 20.1.236.175; 20.1.236.240; 20.1.236.244; 20.1.237.228; 20.1.237.229; 20.1.237.230; 20.1.237.231; 20.1.237.236; 20.1.237.237; 20.1.237.238; 20.1.237.239; 20.1.237.154; 20.1.237.157; 20.1.237.166; 20.1.237.169; 20.1.237.172; 20.1.237.175; 20.1.237.240; 20.1.237.244; 20.1.238.228; 20.1.238.229; 20.1.238.230; 20-1.238.231; 20.1.238.236; 20.1.238.237; 20.1.238.238; 20.1.238.239; 20.1.238.154; 20.1.238.157; 20.1.238.166; 20.1.238.169; 20.1.238.172; 20.1.238.175; 20.1.238.240; 20.1.238.244; 20.1.239.228; 20.1.239.229; 20.1.239.230; 20.1.239.231; 20.1.239.236; 20.1.239.237; 20.1.239.238; 20.1.239.239; 20.1.239.154;20.1.239.157;20.1.239.166;20.1.239.169;20.1.239.172;20.1.239.175; 20.1.239.240; 20.1.239.244; 20.1.154.228; 20.1.154.229; 20.1.154.230; 20.1.154.231; 20.1.154.236; 20.1.154.237; 20.1.154.238; 20.1.154.239; 20.1.154.154; 20.1.154.157; 20.1.154.166; 20.1.154.169; 20.1.154.172; 20.1.154.175; 20.1.154.240; 20.1.154.244; 20.1.157.228; 20.1.157.229; 20.1.157.230; 20.1.157.231; 2Q.I.157.236; 20.1.157.237; 20.1.157.238; 20.1.157.239; 20.1.157.154;20.1.157.157; 20.1.157.166; 20.1.157.169; 20.1.157.172; 20.1.157.175; 20.1.157.240; 20.1.157.244; 20.1.166.228; 20.1.166.229; 20.1.166.230; 20.1.166.231; 20.1.166.236; 20.1.166.237; 20.1.166.238; 20.1.166.239; 20.1.166.154; 20.1.166.157; 20.1.166.166; 20.1.166.169; 20.1.166.172; 20.1.166.175; 20.1.166.240; 20.1.166.244; 20.1.169.228; 20.1.169.229; 20.1.169.230; 20.1.169.231; 20.1.169.236; 20.1.169.237; 20.1.169.238; 20.1.169.239; 20.1.169.154; 20.1.169.157; 20.1.169.166; 20.1.169.169;20.1.169.172;20.1.169.175;20.1.169.240;20.1.169.244; 20.1.172.228; 20.1.172.229; 20.1.172.230; 20.1.172.231; 20.1.172.236; 20.1.172.237; 20.1.172.238; 20.1.172.239; 20.1.172.154; 20.1.172.157; 20.1.172.166; 20.1.172.169; 20.1.172.172; 20.1.172.175; 20.1.172.240; 20.1.172.244; 20.1.175.228; 20.1.175.229; 20.1.175.230; 20.1.175.231; 20.1.175.236; 20.1.175.237; 20.1.175.238; 20.1.175.239; 20.1.175.154; 20.1.175.157; 20.1.175.166; 20.1.175.169; 20.1.175.172; 20.1.175.175; 20.1.175.240; 20.1.175.244; 20.1.240.228; 20.1.240.229; 20.1.240.230; 20.1.240.231; 20.1.240.236; 20.1.240.237; 20.1.240.238; 20.1.240.239; 20.1.240.154; 20.1.240.157; 20.1.240.166; 20.1.240.169; 20.1.240.172; 20-1.240.175; 20.1.240.240; 20.1.240.244; 20.1.244.228; 20.1.244.229; 20.1.244.230; 20.1.244.231; 20.1.244.236; 20.1.244.237; 20.1.244.238; 20.1.244.239; 20.1.244.154; 20.1.244.157; 20.1.244.166; 20.1.244.169; 20.1.244.172; 20.1.244.175; 20.1.244.240; 20.1.244.244;

Prodrugs of20.T

20.J.228.228; 20J.228.229; 20.J.228.230; 20.J.228.231; 20.J.228.236; 20J.228.237; 20J.228.238; 20J.228.239; 20J.228.154; 20.J.228.157; 20J.228.166; 20J.228.169; 20J.228.172; 20J.228.175; 20J.228.240; 20J.228.244; 20J.229.228; 20J.229.229; 20J.229.230; 20J.229.231; 20J.229.236; 20J.229.237; 20.J.229.238; 20J.229.239; 20J.229.154; 20J.229.157; 20J.229.166; 20J.229.169; 20J.229.172; 20J.229.175; 20J.229.240; 20J.229.244; 20J.230.228; 20J.230.229; 20J.230.230; 20J.230.231; 20J.230.236; 20J.230.237; 20J.230.238; 20J.230.239; 20J.230.154; 20J.230.157; 20J.230.166;20J.230.169;20J.230.172; 20J.230.175; 20J.230.240;20J.230.244; 20J.231.228; 20J.231.229; 20J.231.230; 20J.231.231; 20J.231.236; 20J.231.237; 20J.231.238; 20J.231.239; 20J.231.154; 20J.231.157; 20J.231.166; 20J.231.169; 20J.231.172; 20J.231.175; 20J.231.240; 20J.231.244; 20J.236.228; 20J.236.229; 20.J.236.230; 20.J.236.231; 20.J.236.236; 20.J.236.237; 20.J.236.238; 20.J.236.239; 20.J.236.154; 20.J.236.157; 20J.236.166; 20J.236.169; 20J.236.172; 20J.236.175; 20J.236.240; 20J.236.244; 20.J.237.228; 20J.237.229; 20J.237.230; 20J.237.231; 20J.237.236; 20J.237.237; 20J.237.238; 20J.237.239; 20J.237.154; 20J.237.157; 20J.237.166; 20J.237.169; 20J.237.172; 20J.237.175; 20J.237.240; 20J.237.244; 20J.238.228; 20J.238.229; 20J.238.230; 20J.238.231; 20J.238.236; 20J.238.237; 20J.238.238; 20J.238.239; 20J.238.154; 20J.238.157; 20J.238.166; 20J.238.169; 20J.238.172; 20J.238.175; 20J.238.240; 20J.238.244; 20J.239.228; 20J.239.229; 20J.239.230; 20J.239.231; 20J.239.236; 20.J.239.237; 20.J.239.238; 20J.239.239; 20J.239.154; 20J.239.157; 20J.239.166; 20.J.239.169; 20.J.239.172; 20J.239.175; 20J.239.240;20J.239.244;20J.154.228;20J.154.229;20J.154.230; 20J.154.231; 20.J.154.236; 20J.154.237; 20J.154.238; 20J.154.239; 20J.154.154; 20J.154.157; 20.J.154.166; 20J.154.169; 20J.154.172; 20J.154.175; 20.J.154.240; 20J.154.244; 20.J.157.228; 20J.157.229; 20J.157.230; 20J.157.231; 20J.157.236; 20.J.157.237; 20J.157.238; 20J.157.239; 20J.157.154; 20J.157.157; 20.J.157.166; 20J.157.169; 20J.157.172; 20J.157.175; 20J.157.240; 20J.157.244; 20J.166.228; 20J.166.229; 20J.166.230; 20J.166.231; 20J.166.236; 20.J.166.237; 20J.166.238; 20.J.166.239; 20J.166.154; 20J.166.157; 20J.166.166; 20.J.166.169; 20.J.166.172; 20J.166.175; 20J.166.240; 20J.166.244; 20J.169.228; 20J.169.229; 20.J.169.230; 20J.169.231; 20J.169.236; 20J.169.237; 20J.169.238; 20.J.169.239; 20J.169.154; 20J.169.157; 20J.169.166; 20J.169.169; 20J.169.172; 20.J.169.175; 20J.169.240; 20J.169.244; 20J.172.228; 20J.172.229; 20J.172.230; 20.J.172.231; 20J.172.236; 20J.172.237; 20J.172.238; 20.J.172.239; 20J.172.154; 20J.172.157; 20J.172.166; 20J.172.169; 20J.172.172; 20.J.172.175; 20J.172.240; 20J.172.244; 20J.175.228; 20J.175.229; 20J.175.230; 20.J.175.231; 20J.175.236; 20J.175.237; 20J.175.238; 20J.175.239; 20J.175.154; 20.J.175.157; 20J.175.166; 20J.175.169; 20J.175.172; 20J.175.175; 20J.175.240; 20J.175.244; 20J.240.228; 20J.240.229; 20J.240.230; 20J.240.231; 20.J.240.236; 20J.240.237; 20J.240.238; 20J.240.239; 20J.240.154; 20J.240.157; 20.J.240.166; 20J.240.169; 20J.240.172; 20J.240.175; 20J.240.240; 20J.240.244; 20J.244.228; 20J.244.229; 20J.244.230; 20J.244.231; 20J.244.236; 20J.244.237; 20J.244.238; 20J.244.239; 20J.244.154; 20J.244.157; 20J.244.166; 20J.244.169; 20J.244.172; 20J.244.175; 20J.244.240; 20J.244.244;

Prodrugs of20.L

20.L.228.228; 20.L.228.229; 20.L.228.230; 20.L.228.231; 20.L.228.236; 20.L.228.237; 20.L.228.238; 20.L.228.239; 20.L.228.154; 20.L.228.157; 20.L.228.166; 20.L.228.169; 20.L.228.172; 20.L.228.175; 20.L.228.240; 20.L.228.244; 20.L.229.228; 20.L.229.229; 20.L.229.230; 20.L.229.231; 20.L.229.236; 20.L.229.237; 20.L.229.238; 20.L.229.239; 20.L.229.154; 20.L.229.157; 20.L.229.166; 20.L.229.169; 20.L.229.172; 20.L.229.175; 20.L.229.240; 20.L.229.244; 20.L.230.228; 20.L.230.229; 20.L.230.230; 20.L.230.231; 20.L.230.236; 20.L.230.237; 20.L.230.238; 20.L.230.239; 20.L.230.154; 20.L.230.157; 20.L.230.166; 20.L.230.169; 20.L.230.172; 20.L.230.175; 20.L.230.240; 20.L.230.244; 20.L.231.228;20.L.231.229; 20.L.231.230;20.L.231.231;20.L.231.236; 20.L.231.237; 20.L.231.238; 20.L.231.239; 20.L.231.154; 20.L.231.157; 20.L.231.166; 20.L.231.169; 20.L.231.172; 20.L.231.175; 20.L.231.240; 20.L.231.244; 20.L.236.228; 20.L.236.229; 20.L.236.230; 20.L.236.231; 20.L.236.236; 20.L.236.237; 20.L.236.238; 20.L.236.239; 20.L.236.154; 20.L.236.157; 20.L.236.166; 20.L.236.169; 20.L.236.172; 20.L.236.175; 20.L.236.240; 20.L.236.244; 20.L.237.228; 20.L.237.229; 20.L.237.230; 20.L.237.231; 20.L.237.236; 20.L.237.237; 20.L.237.238; 20.L.237.239; 20.L.237.154; 20.L.237.157; 20.L.237.166; 20.L.237.169; 20.L.237.172; 20.L.237.175; 20.L.237.240; 20.L.237.244; 20.L.238.228; 20.L.238.229; 20.L.238.230; 20.L.238.231; 20.L.238.236; 20.L.238.237; 20.L.238.238; 20.L.238.239; 20.L.238.154; 20.L.238.157; 20.L.238.166; 20.L.238.169; 20.L.238.172; 20.L.238.175; 20.L.238.240; 20.L.238.244; 20.L.239.228; 20.L.239.229; 20.L.239.230; 20.L.239.231; 20.L.239.236; 20.L.239.237; 20.L.239.238; 20.L.239.239; 20.L.239.154; 20.L.239.157; 20.L.239.166; 20.L.239.169; 20.L.239.172; 20.L.239.175; 20.L.239.240; 2Q.L.239.244; 20.L.154.228; 20.L.154.229; 20.L.154.230; 2Q.L.154.231; 20.L.154.236; 20.L.154.237; 20.L.154.238; 20.L.154.239; 20.L.154.154; 20.L.154.157; 20.L.154.166; 20.L.154.169; 20.L.154.172; 20.L.154.175; 20.L.154.240; 20.L.154.244; 20.L.157.228; 20.L.157.229; 20.L.157.230; 20.L.157.231; 20.L.157.236; 20.L.157.237; 20.L.157.238; 20.L.157.239; 20.L.157.154; 20.L.157.157; 20.L.157.166; 20.L.157.169; 20.L.157.172; 20.L.157.175; 20.L.157.240; 20.L.157.244; 2Q.L.166.228; 20.L.166.229; 20.L.166.23Q; 20.L.166.231; 20.L.166.236; 20.L.166.237; 20.L.166.238; 20.L.166.239; 20.L.166.154; 20.L.166.157; 20.L.166.166; 20X.166.169; 20.L.166.172; 20.L.166.175; 20.L.166.240; 20.L.166.244; 20.L.169.228; 20.L.169.229; 20.L.169.230; 20.L.169.231; 20.L.169.236; 20.L.169.237; 20.L.169.238; 20.L.169.239; 20.L.169.154; 20.L.169.157; 20.L.169.166; 20.L.169.169; 20.L.169.172; 20.L.169.175; 20.L.169.240; 20.L.169.244; 20.L.172.228; 2Q.L.172.229; 20.L.172.230; 2QL.V72.23l; 20.L.172.236; 20.L.172.237; 20.L.172.238; 20.L.172.239; 20.L.172.154; 20.L.172.157; 20.L.172.166; 20.L.172.169; 20.L.172.172; 20.L.172.175; 20.L.172.240; 20.L.172.244; 20.L.175.228; 20.L.175.229; 20.L.175.230; 20.L.175.231; 20.L.175.236; 20.L.175.237; 20.L.175.238; 20.L.175.239; 20.L.175.154; 20.L.175.157; 20.L.175.166; 20.L.175.169; 20.L.175.172; 20.L.175.175; 20.L.175.240; 20.L.175.244; 20.L.240.228; 20.L.240.229; 20.L.240.230; 20.L.240.231; 20.L.240.236; 20.L.240.237; 20.L.240.238; 20.L.240.239; 20.L.240.154; 20.L.240.157; 20.L.240.166; 2Q.L.240.169; 20.L.240.172; 20.L.240.175; 20.L.240.240; 20.L.240.244; 20.L.244.228; 20.L.244.229; 20.L.244.230; 2Q.L.244.231; 20.L.244.236; 20.L.244.237; 20.L.244.238; 2Q.L.244.239; 20.L.244.154; 20.L.244.157; 20.L.244.166; 20.L.244.169; 20.L.244.172; 20.L.244.175; 20.L.244.240; 20.L.244.244;

Prodrugs of 2Q.O

20.O.228.228; 20.O.228.229; 20.O.228.230; 20.O.228.231; 20.O.228.236; 20.O.228.237; 20.O.228.238; 20.O.228.239; 20.O.228.154; 20.O.228.157; 20.O.228.166; 20.O.228.169; 20.O.228.172; 20.O.228.175; 20.O.228.240; 20.O.228.244; 20.O.229.228; 20.O.229.229; 20.O.229.230; 20.O.229.231; 20.O.229.236; 20.O.229.237; 20.O.229.238; 20.O.229.239; 20.O.229.154; 20.O.229.157; 20.O.229.166; 20.O.229.169; 20.O.229.172; 20.O.229.175; 20.O.229.240; 20.O.229.244; 20.O.230.228; 20.O.230.229; 20.O.230.230; 20.O.230.231; 20.O.230.236; 20.O.230.237; 20.O.230.238; 20.O.230.239; 20.O.230.154; 20.O.230.157; 20.O.230.166; 20.O.230.169; 20.O.230.172; 20.O.230.175; 20.O.230.240; 20.O.230.244; 20.O.231.228; 20.O.231.229; 20.O.231.230; 20.O.231.231; 20.O.231.236; 20.O.231.237; 20.O.231.238; 20.O.231.239; 20.O.231.154; 20.O.231.157; 20.O.231.166; 20.O.231.169; 20.O.231.172; 20.O.231.175; 20.O.231.240; 20.Q.231.244; 20.O.236.228; 20.O.236.229; 20.O.236.230; 20.Q.236.231; 20.O.236.236; 20.O.236.237; 20.O.236.238; 20.O.236.239; 20.O.236.154; 20.O.236.157; 20.O.236.166; 20.O.236.169; 20.O.236.172; 20.O.236.175; 20.O.236.240; 20.O.236.244; 20.O.237.228; 20.O.237.229; 20.O.237.230; 20.O.237.231; 2Q.O.237.236; 20.O.237.237; 20.O.237.238; 20.O.237.239; 20.O.237.154; 20.O.237.157; 20.O.237.166; 20.O.237.169; 2Q.O.237.172; 20.O.237.175; 20.O.237.240; 20.O.237.244; 20.O.238.228; 20.O.238.229; 20.O.238.230; 20.O.238.231; 20.O.238.236; 20.O.238.237; 20.O.238.238; 20.O.238.239; 20.O.238.154; 20.O.238.157; 20.O.238.166; 20.O.238.169; 20.O.238.172; 20.O.238.175; 20.O.238.240; 20.O.238.244; 20.O.239.228; 20.O.239.229; 20.O.239.230; 20.O.239.231; 20.O.239.236; 20.O.239.237; 20.O.239.238; 20.O.239.239; 20.O.239.154; 20.O.239.157; 20.O.239.166; 20.O.239.169; 20.O.239.172; 20.O.239.175; 20.O.239.240; 20.O.239.244; 20.O.154.228; 20.O.154.229; 20.O.154.230; 2Q.O.154.231; 2Q.O.154.236; 20.O.154.237; 20.O.154.238; 20.O.154.239; 20.O.154.154; 20.O.154.157; 20.O.154.166; 20.O.154.169; 20.O.154.172; 20.O.154.175; 2Q.O.154.240; 20.O.154.244; 20.O.157.228; 20.O.157.229; 20.O.157.230; 20.O.157.231; 20.O.157.236; 20.O.157.237; 20.O.157.238; 20.O.157.239; 20.O.157.154; 20.O.157.157; 20.O.157.166; 20.O.157.169; 20.O.157.172; 20.O.157.175; 20.O.157.240; 20.O.157.244; 20.O.166.228; 20.O.166.229; 20.O.166.230; 20.O.166.231; 20.O.166.236; 20.O.166.237; 20.O.166.238; 20.O.166.239; 20.O.166.154; 20.O.166.157; 20.O.166.166; 20.O.166.169; 20.O.166.172; 20.O.166.175; 20.O.166.240; 20.O.166.244; 20.O.169.228; 20.O.169.229; 20.O.169.230; 20.O.169.231; 20.O.169.236; 20.O.169.237; 2Q.O.169.238; 20.O.169.239; 20.O.169.154; 20.O.169.157; 20.O.169.166; 20.O.169.169; 20.O.169.172; 20.O.169.175; 20.O.169.240; 20.O.169.244; 20.O.172.228; 20.O.172.229; 20.O.172.230; 20.O.172.231; 20.O.172.236; 20.CU72.237; 20.O.172.238; 20.O.172.239; 20.O.172.154; 20.O.172.157; 20.O.172.166; 20.O.172.169; 20.O.172.172; 20.O.172.175; 20.O.172.240; 20.O.172.244; 2Q.O.175.228; 20.O.175.229; 20.O.175.230; 20.O.175.231; 20.O.175.236; 2Q.O.175.237; 20.O.175.238; 20.O.175.239; 20.O.175.154; 20.O.175.157; 20.O.175.166; 20.O.175.169; 20.O.175.172; 20.O.175.175; 2Q.O.175.240; 20.O.175.244; 20.O.240.228; 20.O.240.229; 20.O.240.230; 20.O.240.231; 20.O.240.236; 20.O.240.237; 20.O.240.238; 20.O.240.239; 20.O.240.154; 20.O.240.157; 20.O.240.166; 20.O.240.169; 20.O.240.172; 20.O.240.175; 20.O.240.240; 20.O.240.244; 20.O.244.228; 20.O.244.229; 20.O,244.230; 20.O.244.231; 20.O.244.236; 20.O.244.237; 20.O.244.238; 20.O.244.239; 20.O.244.154; 20.O.244.157; 20.O.244.166; 20.O.244.169; 20.O.244.172; 20.O.244.175; 20.O.244.240; 20.O.244.244;

Prodrugs of 20.P

20.P.228.228; 20.P.228.229; 20.P.228.230; 20.P.228.231; 20.P.228.236; 20.P.228.237; 20.P.228.238; 20.P.228.239; 20.P.228.154; 20.P.228.157; 20.P.228.166; 20.P.228.169; 20.P.228.172; 20.P.228.175; 20.P.228.240; 20.P.228.244; 20.P.229.228; 20.P.229.229; 20.P.229.230; 20.P.229.231; 20.P.229.236; 20.P.229.237; 20.P.229.238; 20.P.229.239; 20.P.229.154; 20.P.229.157; 20.P.229.166; 20.P.229.169; 20.P.229.172; 20.P.229.175; 20.P.229.240; 20.P.229.244; 20.P.230.228; 20.P.230.229; 20.P.230.230; 20.P.230.231; 20.P.230.236; 20.P.230.237; 20.P.230.238; 20.P.230.239; 20.P.230.154; 20.P.230.157; 20.P.230.166; 20.P.230.169; 20.P.230.172; 20.P.230.175; 20.P.230.240; 20.P.230.244; 20.P.231.228; 20.P.231.229; 20.P.231.230; 20.P.231.231; 20.P.231.236; 20.P.231.237; 20.P.231.238; 20.P.231.239; 20.P.231.154; 20.P.231.157; 20.P.231.166; 20.P.231.169; 20.P.231.172; 20.P.231.175; 20.P.231.240; 20.P.231.244; 20.P.236.228; 20.P.236.229; 20.P.236.230; 2Q.P.236.231; 20.P.236.236; 20.P.236.237; 20.P.236.238; 20.P.236.239; 20.P.236.154; 20.P.236.157; 20.P.236.166; 20.P.236.169; 20.P.236.172; 20.P.236.175; 20.P.236.240; 20.P.236.244; 20.P.237.228; 20.P.237.229; 20.P.237.230; 20.P.237.231; 20.P.237.236; 20.P.237.237; 20.P.237.238; 20.P.237.239; 20.P.237.154; 20.P.237.157; 20.P.237.166; 20.P.237.169; 20.P.237.172; 20.P.237.175; 20.P.237.240; 20.P.237.244; 20.P.238.228; 20.P.238.229; 20.P.238.230; 20.P.238.231; 20.P.238.236; 20.P.238.237; 20.P.238.238; 20.P.238.239; 20.P.238.154; 20.P.238.157; 20.P.238.166; 20.P.238.169; 20.P.238.172; 20.P.238.175; 20.P.238.240; 20.P.238.244; 20.P.239.228; 20.P.239.229; 20.P.239.230; 20.P.239.231; 20.P.239.236; 20.P.239.237; 20.P.239.238; 20.P.239.239; 20.P.239.154; 20.P.239.157; 20.P.239.166; 20.P.239.169; 20.P.239.172; 20.P.239.175; 20.P.239.240; 20.P.239.244; 20.P.154.228; 2Q.P.154.229; 20.P.154.230; 20.P.154.231; 20.P.154.236; 20.P.154.237; 20.P.154.238; 20.P.154.239; 20.P.154.154; 20.P.154.157; 20.P.154.166; 20.P.154.169; 20.P.154.172; 20.P.154.175; 2Q.P.154.240; 20.P.154.244; 20.P.157.228; 20.P.157.229; 20.P.157.230; 20.P.157.231; 20.P.157.236; 20.P.157.237; 20.P.157.238; 20.P.157.239; 20.P.157.154; 20.P.157.157; 20.P.157.166; 20.P.157.169; 20.P.157.172; 20.P.157.175; 20.P.157.240; 20.P.157.244; 20.P.166.228; 20.P.166.229; 20.P.166.230; 20.P.166.231; 20.P.166.236; 20.P.166.237; 20.P.166.238; 20.P.166.239; 20.P.166.154; 20.P.166.157; 20.P.166.166; 20.P.166.169; 20.P.166.172; 20.P.166.175; 20.P.166.240; 20.P.166.244; 20.P.169.228; 20.P.169.229; 20.P.169.230; 20.P.169.231; 20.P.169.236; 20.P.169.237; 20.P.169.238; 20.P.169.239; 20.P.169.154; 20.P.169.157; 20.P.169.166; 20.P.169.169; 20.P.169.172; 20.P.169.175; 20.P.169.240; 20.P.169.244; 20.P.172.228; 20.P.172.229; 20.P.172.230; 20.P.172.231; 20.P.172.236; 20.P.172.237; 20.P.172.238; 20.P.172.239; 20.P.172.154; 20.P.172.157; 20.P.172.166; 20.P.172.169; 20.P.172.172; 20.P.172.175; 20.P.172.240; 20.P.172.244; 20.P.175.228; 20.P.175.229; 20.P.175.230; 20.P.175.231; 20.P.175.236; 20.P.175.237; 20.P.175.238; 20.P.175.239; 20.P.175.154; 20.P.175.157; 20.P.175.166; 20.P.175.169; 20.P.175.172; 20.P.175.175; 20.P.175.240; 20.P.175.244; 20.P.240.228; 20.P.240.229; 20.P.240.230; 20.P.240.231; 20.P.240.236; 20.P.240.237; 20.P.240.238; 20.P.240.239; 20.P.240.154; 20.P.240.157; 20.P.240.166; 2Q.P.240.169; 20.P.240.172; 20.P.240.175; 20.P.240.240; 20.P.240.244; 20.P.244.228; 20.P.244.229; 20.P.244.230; 20.P.244.231; 20.P.244.236; 20.P.244.237; 20.P.244.238; 20.P.244.239; 20.P.244.154; 20.P.244.157; 20.P.244.166; 20.P.244.169; 20.P.244.172; 20.P.244.175; 20.P.244.240; 20.P.244.244;

Prodrugs of 20.U

20.U.228.228; 20.U.228.229; 20.U.228.230; 20.U.228.231; 20.U.228.236; 20.U.228.237; 20.U.228.238; 20.U.228.239; 20.U.228.154; 20.U.228.157; 20.U.228.166; 20.U.228.169; 20.U.228.172; 20.U.228.175; 20.U.228.240; 20.U.228.244; 20.U.229.228; 20.U.229.229; 20.U.229.230; 20.U.229.231; 20.U.229.236; 20.U.229.237; 20.U.229.238; 20.U.229.239; 20.U.229.154; 20.U.229.157; 20.U.229.166; 20.U.229.169; 20.U.229.172; 20.U.229.175; 20.U..229.240;20.U.229.244; 20.U.230.228;20.U.230,,229;20.U.23Q.230; 20.U.,230.231;20.U.230,,236; 20.U.230.237;20.U.230.238; 20,.U.230.239; 20.U,.230.154;20.U.230,157; 20.U.230166;20.U.230,,169;20.U.230.172; 20.U.,230.175;20.U.230,,240; 20.U.230.244;20.U.231.228; 20,.U.231.229; 20.U.231.230; 20.U.231,,231; 20.U.231.236;20.U.231,,237; 20.U.231.238; 20.U,.231.239; 20.U.231,154; 20.U.231.157; 20.U.231.,166; 20,.U.231.169; 20.U,.231.172; 20.U.231,,175; 20.U.231.240; 20.U.231,,244; 20.U.236.228; 20.U,,236.229;20.U.236,,230;20.U.236.231;20.U.236,,236; 20.U.236.237; 20.U,.236.238; 20.U.236,,239; 20.U.236.154; 20.U.236,157; 20.U.236.166; 20.U.236.169;20.U.236172;20.U.236.175;20.U.236,,240; 20.U.236.244; 20.U..237.228; 20.U.237,,229; 20.U.237.230; 20.U.237,,231; 20 U.237.236; 20.U.237.237;20.U.237.238;20.U.237.239;20.U.237,,154; 20U.237.157; 20.U,.237.166; 2Q.U.237,.169; 20.U.237.172; 20.U.237,175; 20,U.237.240; 20.U,237.244; 20.U.238.228; 20.U.238.229; 20.U.238,.230; 20.U.238.231; 20.U..238.236; 20.U.238,.237; 20.U.238.238; 20.U.238,,239; 20 U.238.154; 20.U.238.157; 20.U.238.166; 20.U.238.169; 20.U.238,,172; 20U.238.175; 20.U.,238.240;20.U.238,,244;20.U.239.228;20.U.239,,229;20U.239.230; 20.U.239.231; 2Q.U.239,236; 20.U.239.237; 20.U.239,,238; 20U.239.239; 20.U.239.154;20.U.239157;20.U.239.166;20.U.239169;20.U.239.172; 20.U.239.175; 20.U.239.240; 20.U.239.244; 20.U.154,,228; 20U.154.229; 20.U.154.230;20.U.154.231;20.U.154.236;20.U.154.,237;20.U.154.238; 20.U.154.239; 20.U.154..154; 20.U154.157;20.U.154,166; 20U.154.169; 20.U.154.172; 20.U.154175; 20.U154.240; 20.U.154,244; 20.U.157.228; 20.U.,157.229; 20.U.157,230; 20.U.157.231; 20.U.157,,236; 20XJ.157.237; 20.U.157.238;20.U.157,239; 20.U.157.154; 20.U157157; 20.U.157.166; 20.U.,157.169;20.U.157,172;20.U.157.175; 20.U.157,240;20■U.157.244; 20.U,,166.228; 20.U.166,229; 20.U166.230; 20.U.166.,231; 20.U.166.236; 20.U,166.237;20.U.166.238;20.U.166.239;20.U.166154;20.U.166.157; 20.U,166.166; 20.U.166,169; 20.U.166.172; 20.U.166,175; 20 U.166.240; 20.U,166.244;20.U.169.,228; 20.U169.229;20.U.169.230;20.U.169.231; 20.U.,169.236;20.U.169,,237; 20.U169.238; 20.U.169,,239; 20U.169.154; 20.U.,169.157; 20.U.169,166; 20.U.169.169; 20.U.169,172; 20.U.169.175; 20.U,169.240;20.U.169,,244; 2Q.U172.228; 20.U.172,,229; 20.U.172.230; 20.U,,172.231; 20.U.172,,236; 20.U.172.237; 20.U.172,,238; 20.U.172.239; 20.U,,172.154;20.U.172,157;20.U,172.166;20.U.172,169;20.U.172.172; 20.U,172.175; 20.U.172,240; 20.U172.244; 20.U.175.228; 20,.U.175.229; 20.U,175.230;20.U.175,,231;20.U175.236;20.U.175,237;20.U.175.238; 20.U.175.239; 20.U.175,154; 20.U,175.157; 20.U.175.166; 20,.U.175.169; 20.U,175.172; 20.U.175.,175; 20.U.175.240;20.U.175.244;20,.U.240.228; 20.U.240.229; 20.U.240.230; 20.U,,240.231; 20.U.240.236; 20,,U.240.237; 20.U.240.238; 20.U.240.239; 20.U,240.154; 20.U.240.157; 20,U.240.166; 20.U,240.169; 20.U.240.172; 20.U,,240.175; 20.U.240.240;20,.U.240.244; 20.U.244.228; 20.U.244.229; 20.U,,244.230; 20.U.244.231; 20,,U.244.236; 20.U.244.237; 20.U.244,238; 20.U,,244.239;20.U.244.154;20,.U.244.157; 20.U.244.166; 20.U.244.169; 20.U,,244.172; 20.U.244.175; 20,,U.244.240; 20.U,244.244; Prodrugs of 2Q.CD

^' 20.CD.228.228; 20.CD.228.229; 20.CD.228.230; 20.CD.228.231; 20.CD.228.236; 20.CD.228.237; 20.CD.228.238; 20.CD.228.239; 20.CD.228.154; 20. CD.228.157; 20.CD.228.166; 20.CD.228.169; 20.CD.228.172; 20.CD.228.175; 20.CD.228.240; 20.CD.228.244; 20.CD.229.228; 20.CD.229.229; 20.CD.229.230; 20.CD.229.231; 20.CD.229.236; 20.CD.229.237; 20.CD.229.238; 20.CD.229.239; 20.CD.229.154; 2Q.CD.229.157; 20.CD.229.166; 20.CD.229.169; 20.CD.229.172; 20.CD.229.175; 20.CP.229.240; 20.CD.229.244; 20.CD.230.228; 20.CD.230.229; 20.CD.230.230; 20.CD.230.231; 20.CD.230.236; 20.CD.230.237; 20.CD.230.238; 20.CD.230.239; 20.CD.230.154; 20.CD.230.157; 20.CD.230.166; 20.CD.230.169; 20.CD.230.172; 20.CD.230.175; 20.CD.230.240; 20.CD.230.244; 20.CD.231.228; 20.CD.231.229; 20.CD.231.230; 20.CD.231.231; 20.CD.231.236; 20.CD.231.237; 20.CD.231.238; 20.CD.231.239; 20.CD.231.154; 2Q.CD.231.157; 20.CD.231.166; 20.CD.231.169; 20.CD.231.172; 20.CD.231.175; 20.CD.231.240; 20.CD.231.244; 20.CD.236.228; 20.CD.236.229; 2Q.CD.236.23Q; 20.CD.236.231; 20.CD.236.236; 20.CD.236.237; 2Q.CD.236.238; 20.CD.236.239; 20.CD.236.154; 20.CD.236.157; 20.CD.236.166; 20.CD.236.169; 20. CD '.236.172; 20.CD.236.175; 20.CD.236.240; 20.CD.236.244; 20.CD.237.228; 20.CD.237.229; 20.CD.237.230; 20.CD.237.231; 20.CD.237.236; 20.CD.237.237; 20.CD.237.238; 20.CD.237.239; 20.CD.237.154; 20.CD.237.157; 20.CD.237.166; 20.CD.237.169; 20.CD.237.172; 2Q.CD.237.175; 20.CD.237.240; 20.CD.237.244; 20.CD.238.228; 20.CD.238.229; 20.CD.238.230; 20.CD.238.231; 20.CD.238.236; 20.CD.238.237; 20.CD.238.238; 20.CD.238.239; 20.CD.238.154; 20.CD.238.157; 20.CD.238.166; 20.CD.238.169; 20.CD.238.172; 20.CD.238.175; 20.CD.238.240; 20.CD.238.244; 20.CD.239.228; 2Q.CD.239.229; 20.CD.239.230; 20.CD.239.231; 20.CD.239.236; 20.CD.239.237; 20.CD.239.238; 20.CD.239.239; 20.CD.239.154; 20.CD.239.157; 20.CD.239.166; 20.CD.239.169; 20.CD.239.172; 20.CD.239.175; 20.CD.239.240; 20.CD.239.244; 20.CD.154.228; 20.CD.154.229; 20.CD.154.230; 20.CD.154.231; 20.CD.154.236; 20.CD.154.237; 20.CD.154.238; 20.CD.154.239; 20.CD.154.154; 20.CD.154.157; 20.CD.154.166; 20.CD.154.169; 20.CD.154.172; 20-CD.154.175; 20.CD.154.240; 20.CD.154.244; 20.CD.157.228; 20.CD.157.229; 20.CD.157.230; 20.CD.157.231; 20.CD.157.236; 20.CD.157.237; 20.CD.157.238; 20.CD.157.239; 20.CD.157.154; 20.CD.157.157; 20.CD.157.166; 20.CD.157.169; 20.CD.157.172; 20.CD.157.175; 20.CD.157.240; 20.CD.157.244; 20.CD.166.228; 20.CD.166.229; 20.CD.166.230; 20.CD.166.231; 20.CD.166.236; 20.CD.166.237; 20.CD.166.238; 20.CD.166.239; 20.CD.166.154; 20.CD.166.157; 20.CD.166.166; 20.CD.166.169; 20.CD.166.172; 20.CD.166.175; 20.CD.166.240; 20.CD.166.244; 20.CD.169.228; 20.CD.169.229; 20.CD.169.230; 20.CD.169.231; 20.CD.169.236; 20.CD.169.237; 20.CD.169.238; 20.CD.169.239; 20.CD.169.154; 20.CD.169.157; 20.CD.169.166; 20.CD.169.169; 20.CD.169.172; 20.CD.169.175; 20.CD.169.240; 20.CD.169.244; 20.CD.172.228; 20. CD.172.229; 20.CD.172.230; 20.CD.172.231; 20.CD.172.236; 20.CD.172.237; 20.CD.172.238; 20.CD.172.239; 20.CD.172.154; 20.CD.172.157; 20.CD.172.166; 20.CD.172.169; 20.CD.172.172; 20.CD.172.175; 20.CD.172.240; 20.CD.172.244; 20.CD.175.228; 20.CD.175.229; 20.CD.175.230; 20.CD.175.231; 20.CD.175.236; 20.CD.175.237; 20.CD.175.238; 20.CD.175.239; 20.CD.175.154; 20.CD.175.157; 20.CD.175.166; 20.CD.175.169; 20.CD.175.172; 20.CD.175.175; 20.CD.175.240; 20.CD.175.244; 20.CD.240.228; 20.CD.240.229; 20.CD.240.230; 20.CD.240.231; 20.CD.240.236; 20.CD.240.237; 20.CD.240.238; 20.CD.240.239; 20.CP.240.154; 2Q.CD.240.157; 20.CD.240.166; 20.CD.240.169; 20.CD.240.172; 20.CD.240.175; 20.CD.240.240; 20.CD.240.244; 20.CD.244.228; 20.CD.244.229; 20.CD.244.230; 20.CD.244.231; 20.CP.244.236; 20.CP.244.237; 20.CP.244.238; 20.CP.244.239; 20.CP.244.154; 20.CP.244.157; 20.CP.244.166; 20.CP.244.169; 20.CP.244.172; 20.CP.244.175; 20.CP.244.240; 20.CP.244.244;

Prodrugs of 20.EB

20.EB.228.228; 20.EB.228.229; 20.EB.228.230; 20.EB.228.231; 20.EB.228.236; 20.EB.228.237; 20.EB.228.238; 20.EB.228.239; 20.EB .228.154; 20.EB.228.157; 20.EB.228.166; 20.EB.228.169; 20.EB.228.172; 20.EB.228.175; 20.EB.228.240; 20.EB.228.244; 20.EB.229.228; 20.EB.229.229; 20.EB.229.230; 20.EB.229.231; 20.EB.229.236; 20.EB.229.237; 2Q.EB.229.238; 20.EB.229.239; 20.EB.229.154; 20.EB.229.157; 20.EB.229.166; 20.EB.229.169; 20.EB.229.172; 20.EB.229.175; 20.EB.229.240; 20.EB.229.244; 20.EB.230.228; 20.EB.230.229; 20.EB.230.230; 20.EB.230.231; 20.EB.230.236; 20.EB.230.237; 20.EB.230.238; 20.EB.230.239; 20.EB.230.154; 20.EB.230.157; 20.EB.230.166; 20.EB.230.169; 20.EB.230.172; 20.EB.230.175; 20.EB.230.240; 20.EB.230.244; 20.EB.231.228; 20.EB.231.229; 20.EB.231.230; 20.EB.231.231; 20.EB.231.236; 20.EB.231.237; 20.EB .231.238; 20.EB.231.239; 20.EB .231.154; 20.EB.231.157; 20.EB.231.166; 20.EB.231.169; 20.EB.231.172; 20.EB.231.175; 20.EB.231.240; 20.EB.231.244; 20.EB.236.228; 20.EB.236.229; 20.EB.236.230; 20.EB.236.231; 20.EB.236.236; 20.EB.236.237; 20.EB.236.238; 20.EB.236.239; 20.EB.236.154; 20.EB.236.157; 20.EB.236.166; 20.EB.236.169; 20.EB.236.172; 20.EB.236.175; 20.EB.236.240; 20.EB.236.244; 20.EB.237.228; 20.EB.237.229; 20.EB.237.230; 20.EB.237.231; 20.EB.237.236; 20.EB.237.237; 20.EB .237.238; 20.EB.237.239; 20.EB.237.154; 20.EB.237.157; 20.EB.237.166; 20.EB.237.169; 20.EB.237.172; 20.EB.237.175; 20.EB.237.240; 20.EB.237.244; 20.EB.238.228; 20.EB.238.229; 20.EB.238.230; 20.EB.238.231; 20.EB.238.236; 20.EB.238.237; 20.EB.238.238; 20.EB.238.239; 20.EB.238.154; 20.EB.238.157; 20. EB.238.166; 20.EB.238.169; 20.EB.238.172; 20.EB.238.175; 20.EB.238.240; 20.EB.238.244; 20.EB.239.228; 20.EB.239.229; 20.EB.239.230; 20.EB.239.231; 20.EB.239.236; 20.EB.239.237; 20.EB.239.238; 20.EB.239.239; 20.EB.239.154; 20.EB.239.157; 20.EB.239.166; 20. EB .239.169; 20.EB.239.172; 20.EB.239.175; 20.EB.239.240; 20.EB.239.244; 20.EB.154.228; 20.EB.154.229; 20.EB.154.230; 20.EB.154.231; 20.EB.154.236; 20.EB.154.237; 20.EB.154.238; 20.EB.154.239; 20.EB.154.154; 20.EB.154.157; 20.EB.154.166; 20.EB.154.169; 20.EB.154.172; 20.EB.154.175; 20.EB.154.240; 20.EB.154.244; 20.EB.157.228; 20.EB.157.229; 20.EB.157.230; 20.EB.157.231; 20.EB.157.236; 20.EB.157.237; 20.EB.157.238; 20.EB.157.239; 20.EB.157.154; 20.EB.157.157; 20.EB.157.166; 20.EB.157.169; 20.EB.157.172; 20.EB.157.175; 20.EB.157.240; 20.EB.157.244; 20.EB.166.228; 20.EB.166.229; 20.EB.166.230; 20.EB.166.231; 20.EB.166.236; 20.EB.166.237; 20.EB.166.238; 20.EB.166.239; 20.EB.166.154; 20.EB.166.157; 20.EB.166.166; 20.EB.166.169; 20.EB.166.172; 20.EB.166.175; 20.EB.166.240; 20.EB.166.244; 20.EB.169.228; 20. EB.169.229; 20.EB.169.230; 20.EB.169.231; 20.EB.169.236; 20.EB.169.237; 2Q.EB.169.238; 20. EB.169.239; 20.EB.169.154; 20.EB.169.157; 20.EB.169.166; 20.EB.169.169; 20.EB.169.172; 20.EB.169.175; 20.EB.169.240; 20.EB.169.244; 20. EB.172.228; 20.EB.172.229; 20.EB.172.230; 20.EB.172.231; 20.EB.172.236; 20.EB.172.237; 20.EB.172.238; 20.EB.172.239; 20.EB.172.154; 20.EB.172.157; 2Q.EB.172.166; 20.EB.172.169; 20.EB.172.172; 20.EB.172.175; 20.EB.172.240; 20.EB.172.244; 20.EB.175.228; 20.EB.175.229; 20.EB.175.230; 20.EB.175.231; 20.EB.175.236; 20.EB.175.237; 20.EB.175.238; 20.EB.175.239; 20.EB.175.154; 20.EB.175.157; 20.EB.175.166; 20.EB.175.169; 20.EB.175.172; 20.EB.175.175; 20.EB.175.240; 20.EB.175.244; 20.EB.240.228; 20.EB.240.229; 20.EB.240.230; 20.EB.24Q.231; 20.EB.240.236; 20.EB.240.237; 20.EB.240.238; 20.EB.240.239; 20.EB.240.154; 20.EB.240.157; 20.EB.240.166; 20.EB.240.169; 20. EB.240.172; 20.EB.240.175; 20.EB.240.240; 20.EB.240.244; 20.EB.244.228; 20.EB.244.229; 20.EB.244.230; 20.EB.244.231; 20.EB.244.236; 20.EB.244.237; 20.EB.244.238; 20.EB.244.239; 20.EB.244.154; 20.EB.244.157; 20.EB.244.166; 20.EB.244.169; 20.EB.244.172; 20.EB.244.175; 20.EB.244.240; 20.EB.244.244;

Prodrugs of 21.B

21.B.228.228; 21.B.228.229; 21.B.228.230; 21.B.228.231; 21.B.228.236; 21.B.228.237; 21.B.228.238; 21.B.228.239; 21.B.228.154; 21.B.228.157; 21.B.228.166; 21.B.228.169; 21.B.228.172; 21.B.228.175; 21.B.228.240; 21.B.228.244; 21.B.229.228; 21.B.229.229; 21.B.229.230; 21.B.229.231; 21.B.229.236; 21.B.229.237; 21.B.229.238; 21.B.229.239; 21.B.229.154; 21.B.229.157; 21.B.229.166; 21.B.229.169; 21.B.229.172; 21.B.229.175; 21.B.229.240; 21.B.229.244; 21.B.230.228; 21.B.230.229; 21.B.230.230; 21.B.230.231; 21.B.230.236; 21.B.230.237; 21.B.23Q.238; 21.B.230.239; 21.B.230.154; 21.B.230.157; 21.B.230.166; 21.B.230.169; 21.B.230.172; 21.B.230.175; 21.B.230.240; 21.B.230.244; 21.B.231.228; 21.B.231.229; 21.B.231.230; 21.B.231.231; 21.B.231.236; 21.B.231.237; 21.B.231.238; 21.B.231.239; 21.B.231.154; 21.B.231.157; 21.B.231.166; 21.B.231.169; 21.B.231.172; 21.B.231.175; 21.B.231.240; 21.B.231.244; 21.B.236.228; 21.B.236.229; 21.B.236.230; 21.B.236.231; 21.B.236.236; 21.B.236.237; 21.B.236.238; 21.B.236.239; 21.B.236.154; 21.B.236.157; 21.B.236.166; 21.B.236.169; 21.B.236.172; 21.B.236.175; 21.B.236.240; 21.B.236.244; 21.B.237.228; 21.B.237.229; 21.B.237.230; 21.B.237.231; 21.B.237.236; 21.B.237.237; 21.B.237.238; 21.B.237.239; 21.B.237.154; 21.B.237.157; 21.B.237.166; 21.B.237.169; 21.B.237.172; 21.B.237.175; 21.B.237.240; 21.B.237.244; 21.B.238.228; 21.B.238.229; 21.B.238.230; 21.B.238.231; 21.B.238.236; 21.B.238.237; 21.B.238.238; 21.B.238.239; 21.B.238.154; 21.B.238.157; 21.B.238.166; 21.B.238.169; 21.B.238.172; 21.B.238.175; 21.B.238.240; 21.B.238.244; 21.B.239.228; 21.B.239.229; 21.B.239.230; 21.B.239.231; 21.B.239.236; 21.B.239.237; 21.B.239.238; 21.B.239.239; 21.B.239.154; 21.B.239.157; 21.B.239.166; 21.B.239.169; 21.B.239.172; 21.B.239.175; 21.B.239.240; 21.B.239.244; 21.B.154.228; 21.B.154.229; 21.B.154.230; 21.B.154.231; 21.B.154.236; 21.B.154.237; 21.B.154.238; 21.B.154.239; 21.B.154.154; 21.B.154.157; 21.B.154.166; 21.B.154.169; 21.B.154.172; 21.B.154.175; 21.B.154.240; 21.B.154.244; 21.B.157.228; 21.B.157.229; 21.B.157.230; 21.B.157.231; 21.B.157.236; 21.B.157.237; 21.B.157.238; 21.B.157.239; 21.B.157.154; 21.B.157.157; 21.B.157.166; 21.B.157.169; 21.B.157.172; 21.B.157.175; 21.B.157.240; 21.B.157.244; 21.B.166.228; 21.B.166.229; 21.B.166.230; 21.B.166.231; 21.B.166.236; 21.B.166.237; 21.B.166.238; 21.B.166.239; 21.B.166.154; 21. B.166.157; 21.B.166.166; 21.B.166.169; 21.B.166.172; 21.B.166.175; 21.B.166.240; 21.B.166.244; 21.B.169.228; 21.B.169.229; 21.B.169.230; 21.B.169.231; 21.B.169.236; 21.B.169.237; 21.B.169.238; 21.B.169.239; 21.B.169.154; 21.B.169.157; 21.B.169.166; 21.B.169.169; 21.B.169.172; 21.B.169.175; 21.B.169.240; 21.B.169.244; 21.B.172.228; 21.B.172.229; 21.B.172.230; 21.B.172.231; 21.B.172.236; 21.B.172.237; 21.B.172.238; 21.B.172.239; 21.B.172.154; 21.B.172.157; 21.B.172.166; 21.B.172.169; 21.B.172.172; 21.B.172.175; 21.B.172.240; 21.B.172.244; 21.B.175.228; 21.B.175.229; 21.B.175.230; 21.B.175.231; 21.B.175.236; 21.B.175.237; 21.B.175.238; 21.B.175.239; 21.B.175.154; 21.B.175.157; 21.B.175.166; 21.B.175.169; 21.B.175.172; 21.B.175.175; 21.B.175.240; 21.B.175.244; 21.B.240.228; 21.B.240.229; 21.B.24Q.230; 21.B.240.231; 21.B.240.236; 21.B.240.237; 21.B.24Q.238; 21.B.240.239; 21.B.240.154; 21.B.240.157; 21.B.240.166; 21.B.240.169; 21.B.240.172; 21.B.240.175; 21.B.240.240; 21.B.240.244; 21.B.244.228; 21.B.244.229; 21.B.244.230; 21.B.244.231; 21.B.244.236; 21.B.244.237; 21.B.244.238; 21.B.244.239; 21.B.244.154; 21.B.244.157; 21.B.244.166; 21.B.244.169; 21.B.244.172; 21.B.244.175; 21.B.244.240; 21.B.244.244;

Prodrugs of 21. D

21.D.228.228; 21.D.228.229; 21.D.228.230; 21.D.228.231; 21.D.228.236; 21.D.228.237; 21.D.228.238; 21.D.228.239; 21.D.228.154; 21.D.228.157; 21.D.228.166; 21.D.228.169; 21.D.228.172; 21.D.228.175; 21.D.228.240; 21.D.228.244; 21.D.229.228; 21.D.229.229; 21.D.229.230; 21.D.229.231; 21.D.229.236; 21.D.229.237; 21.D.229.238; 21.D.229.239; 21.D.229.154; 21.D.229.157; 21.D.229.166; 21.D.229.169; 21.D.229.172; 21.D.229.175; 21.D.229.240; 21.D.229.244; 21.D.230.228; 21.D.230.229; 21.D.230.230; 21.D.230.231; 21.U230.236; 21.D.230.237; 21.D.230.238; 21.D.230.239; 21.D.230.154; 21.D.230.157; 21.D.230.166; 21.D.230.169; 21.D.230.172; 21.D.230.175; 21.D.230.240; 21.D.230.244; 21.D.231.228; 21.D.231.229; 21.D.231.230; 21.D.231.231; 21.D. ,231.236; 21.D.231.237; 21.D.231.238; 21.D.231.239; 21.D.231.154; 21.D.231.157; 21.D.231.166; 21.D.231.169; 21.D.231.172; 21.D.231.175; 21.U231.240; 21.D.231.244; 21.D.236.228; 21.D.236.229; 21.D.236.230; 21.D.236.231; 21.D.236.236; 21.D.236.237; 21.D.236.238; 21.U236.239; 21.D.236.154; 21.U236.157; 21.D.236.166; 21.D.236.169; 21.D.236.172; 21.D.236.175; 21.D.236.240; 21.D.236.244; 21.D.237.228; 21.D.237.229; 21.D.237.230; 21.D.237.231; 21.D.237.236; 21.D.237.237; 21.D.237.238; 21.D.237.239; 21.D.237.154; 21.D.237.157; 21.D.237.166; 21.D.237.169; 21.D.237.172; 21.D.237.175; 21.D.237.240; 21.D.237.244; 21.D.238.228; 21.D.238.229; 21.D.238.230; 21.D.238.231; 21.D.238.236; 21.D.238.237; 21.D.238.238; 21.D.238.239; 21.D.238.154; 21.D.238.157; 21.D.238.166; 21.D.238.169; 21.D.238.172; 21.D.238.175; 21.D.238.240; 21.D.238.244; 21.D.239.228; 21.D.239.229; 21.D.239.230; 21.D.239.231; 21.D.239.236; 21.D.239.237; 21.D.239.238; 21.D.239.239; 21.D.239.154; 21.D.239.157; 21.D.239.166; 21.D.239.169; 21.D.239.172; 21.D.239.175; 21.D.239.240; 21.D.239.244; 21.D.154.228; 21.D.154.229; 21.D.154.230; 21.D.154.231; 21.D.154.236; 21.D.154.237; 21.D.154.238; 21.D.154.239; 21.D.154.154; 21.D.154.157; 21.D.154.166; 21.D.154.169; 21.D.154.172; 21.D.154.175; 21.D.154.240; 21.D.154.244; 21.D.157.228; 21.D.157.229; 21.D.157.230; 21.D.157.231; 21.D.157.236; 21.D.157.237; 21.D.157.238; 21.D.157.239; 21.D.157.154; 21.D.157.157; 21.D.157.166; 21.D.157.169; 21.D.157.172; 21.D.157.175; 21.D.157.240; 21.D.157.244; 21.D.166.228; 21.D.166.229; 21.D.166.230; 21.P.166.231; 21.D.166.236; 21.D.166.237; 21.D.166.238; 21.D.166.239; 21.D.166.154; 21.D.166.157; 21.D.166.166; 21.D.166.169; 21.D.166.172; 21.D.166.175; 21.D.166.240; 21.D.166.244; 21.D.169.228; 21.D.169.229; 21.D.169.230; 21.D.169.231; 21.D.16, 9.236; 21.D.169.237; 21.D.169.238; 21.D.169.239; 21.D.169.154; 21.D.169.157; 21.D.169.166; 21.D.169.169; 21.D.169.172; 21.D.169.175; 21.U169.240; 21.D.169.244; 21.D.172.228; 21.D.172.229; 21.D.172.230; 21.D.172.231; 21.D.172.236; 21.D.172.237; 21.D.172.238; 21.D.172.239; 21.D.172.154; 21.D.172.157; 21.D.172.166; 21.D.172.169; 21.D.172.172; 21.D.172.175; 21.D.172.240; 21.D.172.244; 21.D.175.228; 21.D.175.229; 21.D.175.230; 21.D.175.231; 21.D.175.236; 21.D.175.237; 21.D.175.238; 21.D.175.239; 21.D.175.154; 21.D.175.157; 21.D.175.166; 21.D.175.169; 21.D.175.172; 21.D.175.175; 21.D.175.240; 21.D.175.244; 21.D.240.228; 21.D.240.229; 21.D.240.230; 21.D.240.231; 21.D.240.236; 21.D.240.237; 21.D.240.238; 21.D.240.239; 21.D.240.154; 21.D.240.157; 21.D.240.166; 21.D.240.169; 21.D.240.172; 21.D.240.175; 21.D.240.240; 21.D.240.244; 21.D.244.228; 21.D.244.229; 21.D.244.230; 21.D.244.231; 21.D.244.236; 21.D.244.237; 21.D.244.238; 21.D.244.239; 21.D.244.154; 21.D.244.157; 21.D.244.166; 21.D.244.169; 21.D.244.172; 21.D.244.175; 21.D.244.240; 21.D.244.244;

Prodrugs of 21.AB

21.AB.228.228; 21.AB.228.229; 21.AB.228.230; 21.AB.228.231; 21.AB.228.236; 21.AB.228.237; 21.AB.228.238; 21.AB.228.239; 21.AB.228.154; 21.AB.228.157; 21.AB.228.166; 21.AB.228.169; 21.AB.228.172; 21.AB.228.175; 21.AB.228.240; 21.AB.228.244; 21.AB.229.228; 21.AB.229.229; 21.AB.229.230; 21.AB.229.231; 21.AB.229.236; 21.AB.229.237; 21.AB.229.238; 21.AB.229.239; 21.AB.229.154; 21.AB.229.157; 21.AB.229.166; 21.AB.229.169; 21.AB.229.172; 21.AB.229.175; 21.AB.229.240; 21.AB.229.244; 21.AB.230.228; 21.AB.230.229; 21.AB.230.230; 21.AB.230.231; 21.AB.230.236; 21.AB.23Q.237; 21.AB.230.238; 21. AB .230.239; 21.AB.230.154; 21.AB.230.157; 21.AB.230.166; 21.AB.230.169; 21.AB.230.172; 21.AB.230.175; 21.AB.230.240; 21.AB.230.244; 21.AB.231.228; 21.AB.231.229; 21.AB.231.230; 21.AB.231.231; 21.AB.231.236; 21.AB.231.237; 21.AB.231.238; 21.AB.231.239; 21.AB.231.154; 21.AB.231.157; 21.AB.231.166; 21.AB.231.169; 21.AB.231.172; 21.AB.231.175; 21.AB.231.240; 21.AB.231.244; 21.AB.236.228; 21.AB.236.229; 21.AB.236.230; 21.AB.236.231; 21.AB.236.236; 21.AB.236.237; 21.AB.236.238; 21.AB.236.239; 21.AB.236.154; 21.AB.236.157; 21.AB.236.166; 21.AB.236.169; 21.AB.236.172; 21.AB.236.175; 21.AB.236.240; 21.AB.236.244; 21.AB.237.228; 21.AB.237.229; 21.AB.237.230; 21.AB.237.231; 21.AB.237.236; 21.AB.237.237; 21.AB.237.238; 21.AB.237.239; 21.AB.237.154; 21.AB.237.157; 21.AB.237.166; 21.AB.237.169; 21.AB.237.172; 21.AB.237.175; 21.AB.237.240; 21.AB.237.244; 21.AB.238.228; 21.AB.238.229; 21.AB.238.230; 21.AB.238.231; 21.AB.238.236; 21.AB.238.237; 21.AB.238.238; 21.AB.238.239; 21.AB.238.154; 21.AB.238.157; 21.AB.238.166; 21.AB.238.169; 21.AB.238.172; 21.AB.238.175; 21.AB.238.240; 21.AB.238.244; 21.AB.239.228; 21.AB.239.229; 21.AB.239.230; 21.AB.239.231; 21.AB.239.236; 21.AB.239.237; 21.AB.239.238; 21.AB.239.239; 21.AB.239.154; 21.AB.239.157; 21.AB.239.166; 21.AB.239.169; 21.AB.239.172; 21.AB.239.175; 21.AB.239.240; 21.AB.239.244; 21. AB.154.228; 21.AB.154.229; 21.AB.154.230; 21.AB.154.231; 21.AB.154.236; 21.AB.154.237; 21.AB.154.238; 21.AB.154.239; 21.AB.154.154; 21.AB.154.157; 21.AB.154.166; 21.AB.154.169; 21.AB.154.172; 21.AB.154.175; 21.AB.154.240; 21.AB.154.244; 21.AB.157.228; 21.AB.157.229; 21.AB.157.230; 21.AB.157.231; 21.AB.157.236; 21.AB.157.237; 21.AB.157.238; 21.AB.157.239; 21.AB.157.154; 21.AB.157.157; 21.AB.157.166; 21.AB.157.169; 21.AB.157.172; 21.AB.157.175; 21.AB.157.240; 21.AB.157.244; 21.AB.166.228; 21.AB.166.229; 21.AB.166.230; 21.AB.166.231; 21.AB.166.236; 21.AB.166.237; 21.AB.166.238; 21.AB.166.239; 21.AB.166.154; 21.AB.166.157; 21.AB.166.166; 21.AB.166.169; 21.AB.166.172; 21.AB.166.175; 21.AB.166.240; 21.AB.166.244; 21.AB.169.228; 21.AB.169.229; 21.AB.169.230; 21.AB.169.231; 21.AB.169.236; 21.AB.169.237; 21.AB.169.238; 21.AB.169.239; 21.AB.169.154; 21.AB.169.157; 21.AB.169.166; 21.AB.169.169; 21.AB.169.172; 21.AB.169.175; 21.AB.169.240; 21.AB.169.244; 21.AB.172.228; 21.AB.172.229; 21.AB.172.230; 21.AB.172.231; 21.AB.172.236; 21.AB.172.237; 21.AB.172.238; 21.AB.172.239; 21.AB.172.154; 21.AB.172.157; 21.AB.172.166; 21.AB.172.169; 21.AB.172.172; 21.AB.172.175; 21.AB.172.240; 21.AB.172.244; 21.AB.175.228; 21.AB.175.229; 21.AB.175.230; 21.AB.175.231; 21.AB.175.236; 21.AB.175.237; 21.AB.175.238; 21.AB.175.239; 21.AB.175.154; 21.AB.175.157; 21.AB.175.166; 21.AB.175.169; 21.AB.175.172; 21.AB.175.175; 21.AB.175.240; 21.AB.175.244; 21.AB.240.228; 21.AB.24Q.229; 21.AB.240.230; 21.AB.240.231; 21.AB.240.236; 21.AB.240.237; 21.AB.240.238; 21.AB.240.239; 21.AB.240.154; 21.AB.24Q.157; 21.AB.240.166; 21.AB.240.169; 21.AB.240.172; 21.AB.240.175; 21.AB.240.240; 21.AB.240.244; 21.AB.244.228; 21.AB.244.229; 21.AB.244.230; 21.AB.244.231; 21.AB.244.236; 21.AB.244.237; 21.AB.244.238; 21.AB.244.239; 21.AB.244.154; 21.AB.244.157; 21.AB.244.166; 21.AB.244.169; 21.AB.244.172; 21.AB.244.175; 21.AB.244.240; 21.AB.244.244;

Prodrugs of 21.BI

21.BI.228.228; 21.BI.228.229; 21.BI.228.230; 21.BI.228.231; 21.BI.228.236; 21.BI.228.237; 21.BI.228.238; 21.BI.228.239; 21.BI.228.154; 21.BI.228.157; 21.BI.228.166; 21.BI.228.169; 21.BI.228.172; 21.BI.228.175; 21.BI.228.240; 21.BI.228.244; 21.BI.229.228; 21.BI.229.229; 21.BI.229.230; 21.BI.229.231; 21.BI.229.236; 21.BI.229.237; 21.BI.229.238; 21.BI.229.239; 21.BI.229.154; 21.BI.229.157; 21.BI.229.166; 21.BI.229.169; 21.BI.229.172; 21.BI.229.175; 21.BI.229.240; 21.BI.229.244; 21.BI.230.228; 21.BI.230.229; 21.BI.230.230; 21.BI.230.231; 21.BI.230.236; 21.BI.230.237; 21.BI.230.238; 21.BI.230.239; 21.BI.230.154; 21.BI.230.157; 21.BI.230.166; 21.BI.230.169; 21.BI.230.172; 21.BI.230.175; 21.BI.230.240; 21.BI.230.244; 21.BI.231.228; 21.BI.231.229; 21.BI.231.230; 21.BI.231.231; 21.BI.231.236; 21.BI.231.237; 21.BI.231.238; 21.BI.231.239; 21.BI.231.154; 21.BI.231.157; 21.BI.231.166; 21.BI.231.169; 21.BI.231.172; 21.BI.231.175; 21.BI.231.240; 21.BI.231.244; 21.BI.236.228; 21.BL236.229; 21.BI.236.230; 21.BI.236.231; 21.BI.236.236; 21.BL236.237; 21.BI.236.238; 21.BI.236.239; 21.BI.236.154; 21.BI.236.157; 21.BI.236.166; 21.BI.236.169; 21.BI.236.172; 21.BI.236.175; 21.BI.236.240; 21.BI.236.244; 21.BI.237.228; 21.BI.237.229; 21.BI.237.230; 21.BI.237.231; 21.BI.237.236; 21.BI.237.237; 21.BI.237.238; 21.BI.237.239; 21.BI.237.154; 21.BI.237.157; 21.BI.237.166; 21.BI.237.169; 21.BI.237.172; 21.BI.237.175; 21.BI.237.240; 21.BI.237.244; 21.BI.238.228; 21.BI.238.229; 21.BI.238.230; 21.BI.238.231; 21.BI.238.236; 21.BI.238.237; 21.BI.238.238; 21.BI.238.239; 21.BI.238.154; 21.BI.238.157; 21.BI.238.166; 21.BI.238.169; 21.BI.238.172; 21.BI.238.175; 21.BI.238.240; 21.BI.238.244; 21.BI.239.228; 21.BI.239.229; 21.BI.239.230; 21.BI.239.231; 21.BI.239.236; 21.BI.239.237; 21.BL239.238; 21.BI.239.239; 21.BL239.154; 21.BL239.157; 21.BL239.166; 21.BL239.169; 21.BI.239.172; 21.BL239.175; 21.BI.239.240; 21.BI.239.244; 21.BI.154.228; 21.BI.154.229; 21.BI.154.230; 21.BI.154.231; 21.BI.154.236; 21.BI.154.237; 21.BI.154.238; 21.BI.154.239; 21. BI.154.154; 21.BI.154.157; 21.BI.154.166; 21.BI.154.169; 21.BI.154.172; 21.BI.154.175; 21.BI.154.240; 21.BI.154.244; 21.BL157.228; 21.BI.157.229; 21. BI.157.230; 21.BL157.231; 21.BI.157.236; 21.BI.157.237; 21.BI.157.238; 21.BI.157.239; 21.BI.157.154; 21.BI.157.157; 21.BI.157.166; 21.BI.157.169; 21.BI.157.172; 2131.157.175; 21. BI.157.240; 21.BI.157.244; 21.BI.166.228; 21.BI.166.229; 21.BI.166.230; 21.BI.166.231; 21.BI.166.236; 21.BI.166.237; 21.BI.166.238; 21.BI.166.239; 21.BI.166.154; 21.BI.166.157; 21.BI.166.166; 21.BI.166.169; 21.BI.166.172; 21.BI.166.175; 21.BI.166.240; 21.BI.166.244; 21.BI.169.228; 21.BI.169.229; 21.BI.169.230; 21.BI.169.231; 21.BI.169.236; 21.BI.169.237; 21.BI.169.238; 21.BI.169.239; 21.BI.169.154; 21.BI.169.157; 21.BI.169.166; 21.BI.169.169; 21.BI.169.172; 21.BI.169.175; 21.BI.169.240; 21.BI.169.244; 21.BI.172.228; 21.BI.172.229; 21.BI.172.230; 21.BI.172.231; 21. BI.172.236; 21.BI.172.237; 21.BI.172.238; 21.BI.172.239; 21.BI.172.154; 21.BI.172.157; 21.BI.172.166; 21.BI.172.169; 21.BI.172.172; 21.BI.172.175; 21.BI.172.240; 21.BI.172.244; 21. BI.175.228; 21.BI.175.229; 21.BI.175.230; 21.BI.175.231; 21.BI.175.236; 21.BI.175.237; 21.BI.175.238; 21.BI.175.239; 21.BI.175.154; 21.BI.175.157; 21.BI.175.166; 21.BI.175.169; 21.BI.175.172; 21.BI.175.175; 21.BL175.240; 21.BI.175.244; 21.BI.240.228; 21.BI.240.229; 21.BI.240.230; 21.BI.240.231; 21.BI.240.236; 21.BI.240.237; 21.BI.240.238; 21.BI.240.239; 21.BI.240.154; 21.BI.240.157; 21.BI.240.166; 21.BI.240.169; 21.BL240.172; 21.BI.240.175; 21.BI.240.240; 21.BI.240.244; 21.BI.244.228; 21.BI.244.229; 21.BI.244.230; 21.BI.244.231; 21.BI.244.236; 21.BI.244.237; 21.BI.244.238; 21.BI.244.239; 21.BI.244.154; 21.BI.244.157; 21.BI.244.166; 21.BI.244.169; 21.BI.244.172; 21.BI.244.175; 21.BI.244.240; 21.BI.244.244;

Prodrugs of 21.1

21.1.228.228; 21.1.228.229; 21.1.228.230; 21.1.228.231; 21.1.228.236; 21.1.228.237; 21.1.228.238; 21.1.228.239; 21.1.228.154; 21.1.228.157; 21.1.228.166; 21.1.228.169; 21.1.228.172; 21.1.228.175; 21.1.228.240; 21.1.228.244; 21.1.229.228; 21.1.229.229; 21.1.229.230; 21.1.229.231; 21.1.229.236; 21.1.229.237; 21.1.229.238; 21.1.229.239; 21.1.229.154; 21.1.229.157; 21.1229.166; 21.1.229.169; 21.1.229.172; 21.1.229.175; 21.1.229.240; 21.1.229.244; 21.1.230.228; 21.1.230.229; 21.1.230.230; 21.1.230.231; 21.1.230.236; 21.1.230.237; 21.1.230.238; 21.1.230.239; 21.1.230.154; 21.1.230.157; 21.1.230.166; 21.1.230.169; 21.1.230.172; 21.1.230.175; 21.1.230.240; 21.1.230.244; 21.1.231.228; 21.1.231.229; 21.1.231.230; 21.1.231.231; 21.1.231.236; 21.1.231.237; 21.1.231.238; 21.1.231.239; 21.1.231.154; 21.1.231.157; 21.1.231.166; 21.1.231.169; 21.1.231.172; 21.1.231.175; 21.1.231.240; 21.1.231.244; 21.1.236.228; 21.1.236.229; 21.1.236.230; 21.1.236.231; 21.1.236.236; 21.1.236.237; 21.1.236.238; 21.1.236.239; 21.1.236.154; 21.1.236.157; 21.1.236.166; 21.1.236.169; 21.1.236.172; 21.1.236.175; 21.1.236.240; 21.1.236.244; 21.1.237.228; 21.1.237.229; 21.1.237.230; 21.1.237.231; 21.1.237.236; 21.1.237.237; 21.1.237.238; 21.1.237.239; 21.1.237.154; 21.1.237.157; 21.1.237.166; 21.1.237.169; 21.1.237.172; 21.1.237.175; 21.1.237.240; 21.1.237.244; 21.1.238.228; 21.1.238.229; 21.1.238.230; 21.1.238.231; 21.1.238.236; 21.1.238.237; 21.1.238.238; 21.1.238.239; 21.1.238.154; 21.1.238.157; 21.1.238.166; 21.1.238.169; 21.1.238.172; 21.1.238.175; 21.1.238.240; 21.1.238.244; 21.1.239.228; 21.1.239.229; 21.1.239.230; 21.1.239.231; 21.1.239.236; 21.1.239.237; 21.1239.238; 21.1.239.239; 21.1.239.154; 21.1.239.157; 21.1.239.166; 21.1.239.169; 21.1.239.172; 21.1.239.175; 21.1.239.240; 21.1.239.244; 21.1.154.228; 21.1.154.229; 21.1.154.230; 21.1.154.231; 21.1.154.236; 21.1.154.237; 21.1.154.238; 21.1.154.239; 21.1.154.154; 21.1.154.157; 21.1.154.166; 21.1.154.169; 21.1.154.172; 21.1.154.175; 21.1.154.240; 21.1.154.244; 21.1.157.228; 21.1.157.229; 21.1.157.230; 21.1.157.231; 21.1.157.236; 21.1.157.237; 21.1.157.238; 21.1.157.239; 21.1.157.154; 21.1.157.157; 21.1.157.166; 21.1.157.169; 21.1.157.172; 21.1.157.175; 21.1.157.240; 21.1.157.244; 21.1.166.228; 21.1.166.229; 21.1.166.230; 21.1.166.231; 21.1.166.236; 21.1.166.237; 21.1.166.238; 21.1.166.239; 21.1.166.154; 21.1.166.157; 21.1.166.166; 21.1.166.169; 21.1.166.172; 21.1.166.175; 21.1.166.240; 21.1.166.244; 21.1.169.228; 21.1.169.229; 21.1.169.230; 21.1.169.231; 21.1.169.236; 21.1.169.237; 21.1.169.238; 21.1.169.239; 21.1.169.154; 21.1.169.157; 21.1.169.166; 21.1.169.169; 21.1.169.172; 21.1.169.175; 21.1.169.240; 21.1.169.244; 21.1.172.228; 21.1.172.229; 21.1.172.230; 21.1.172.231; 21.1.172.236; 21.1.172.237; 21.1.172.238; 21.1.172.239; 21.1.172.154; 21.1.172.157; 21.1.172.166; 21.1.172.169; 21.1.172.172; 21.1.172.175; 21.1.172.240; 21.1.172.244; 21.1.175.228; 21.1.175.229; 21.1.175.230; 21.1.175.231; 21.1.175.236; 21.1.175.237; 21.1.175.238; 21.1.175.239; 21.1.175.154; 21.1.175.157; 21.1.175.166; 21.1.175.169; 21.1.175.172; 21.1.175.175; 21.1.175.240; 21.1.175.244; 21.1.240.228; 21.1.240.229; 21.1.240.230; 21.1.240.231; 21.1.240.236; 21.1.240.237; 21.1.240.238; 21.1.240.239; 21.1.240.154; 21.1.240.157; 21.1.240.166; 21.1.240.169; 21.1.240.172; 21.1.240.175; 21.1.240.240; 21.1.240.244; 21.1.244.228; 21.1.244.229; 21.1.244.230; 21.1.244.231; 21.1.244.236; 21.1.244.237; 21.1.244.238; 21.1.244.239; 21.1.244.154; 21.1.244.157; 21.1.244.166; 21.1.244.169; 21.1.244.172; 21.1.244.175; 21.1.244.240; 21.1.244.244;

Prodrugs of 21 J

21J.228.228; 21.J.228.229; 21.J.228.230; 21J.228.231; 21.J.228.236; 21J.228.237; 21J.228.238; 21 J.228.239; 21J.228.154; 21J.228.157; 21J.228.166; 21.J.228.169; 21J.228.172; 21J.228.175; 21J.228.240; 21J.228.244; 21 J.229.228; 21.J.229.229; 21J.229.230; 21J.229.231; 21 J.229.236; 21 J.229.237; 21.J.229.238; 21J.229.239; 21J.229.154; 21J.229.157; 21J.229.166; 21.J.229.169; 21J.229.172; 21.J.229.175; 21J.229.240; 21J.229.244; 21J.230.228; 21 J.230.229; 21J.230.230; 21.J.230.231; 21.J.230.236; 21.J.230.237; 21J.230.238; 21.J.230.239; 21.J.230.154; 21.J.230.157; 21J.230.166; 21J.230.169; 21J.230.172; 21J.230.175; 21J.230.240; 21J.230.244; 21J.231.228; 21J.231.229; 21J.231.230; 21J.231.231; 21J.231.236; 21J.231.237; 21J.231.238; 21J.231.239; 21.J.231.154; 21J.231.157; 21J.231.166; 21J.231.169; 21J.231.172; 21J.231.175; 21J.231.240; 21J.231.244; 21J.236.228; 21J.236.229; 21J.236.230; 21J.236.231; 21J.236.236; 21J.236.237; 21J.236.238; 21J.236.239; 21J.236.154; 21J.236.157; 21J.236.166; 21J.236.169; 21J.236.172; 21J.236.175; 21.J.236.240; 21.J.236.244; 21J.237.228; 21J.237.229; 21J.237.230; 21J.237.231; 21J.237.236; 21J.237.237; 21J.237.238; 21J.237.239; 21J.237.154; 21J.237.157; 21J.237.166; 21J.237.169; 21J.237.172; 21.J.237.175; 21.J.237.240; 21J.237.244; 21J.238.228;21J.238.229;21J.238.230; 21J.238.231;21J.238.236;21.J.238.237; 21J.238.238; 21J.238.239; 21J.238.154; 21J.238.157; 21J.238.166; 21J.238.169; 21J.238.172; 21J.238.175; 21J.238.240; 21J.238.244; 21.J.239.228; 21J.239.229; 21J.239.230; 21J.239.231; 21J.239.236; 21J.239.237; 21J.239.238; 21J.239.239; 21J.239.154; 21J.239.157; 21J.239.166; 21J.239.169; 21J.239.172; 21J.239.175; 21J.239.240; 21J.239.244; 21J.154.228; 21J.154.229; 21J.154.230; 21J.154.231; 21J.154.236; 21J.154.237; 21J.154.238; 21J.154.239; 21J.154.154; 21.J.154.157; 21J.154.166; 21J.154.169; 21J.154.172; 21J.154.175; 21J.154.240; 21J.154.244; 21J.157.228; 21J.157.229; 21J.157.230; 21J.157.231; 21J.157.236; 21J.157.237; 21J.157.238; 21J.157.239;21J.157.154;21J.157.157; 21J.157.166; 21J.157.169; 21J.157.172; 21J.157.175; 21J.157.240; 21J.157.244; 21J.166.228; 21J.166.229; 21J.166.230; 21J.166.231; 21J.166.236; 21J.166.237; 21J.166.238; 21J.166.239; 21J.166.154; 21J.166.157; 21J.166.166; 21.J.166.169; 21.J.166.172; 21J.166.175; 21J.166.240; 21J.166.244; 21J.169.228; 21J.169.229; 21J.169.230; 21J.169.231; 21.J.169.236; 21J.169.237; 21J.169.238; 21J.169.239; 21J.169.154; 21J.169.157; 21J.169.166; 21J.169.169; 21J.169.172; 21J.169.175; 21J.169.240; 21J.169.244; 21J.172.228; 21J.172.229; 21J.172.230; 21J.172.231; 21J.172.236; 21J.172.237; 21J.172.238; 21J.172.239; 21J.172.154; 21J.172.157; 21J.172.166; 21J.172.169; 21J.172.172; 21J.172.175; 21J.172.240; 21J.172.244; 21J.175.228; 21J.175.229; 21J.175.230; 21J.175.231; 21J.175.236; 21J.175.237; 21J.175.238; 21J.175.239; 21J.175.154; 21J.175.157; 21J.175.166; 21J.175.169; 21J.175.172; 21J.175.175; 21J.175.240; 21J.175.244; 21J.24Q.228; 21J.240.229; 21J.240.230; 21J.240.231; 21.J.240.236; 21J.240.237; 21J.240.238; 21J.240.239; 21J.240.154; 21J.240.157; 21J.240.166; 21J.240.169; 21J.240.172; 21J.240.175;21J.240.240;21J.240.244; 21.J.244.228; 21.J.244.229; 21.J.244.230; 21J.244.231; 21.J.244.236; 21.J.244.237; 21.J.244.238; 21.J.244.239; 21J.244.154; 21J.244.157; 21J.244.166; 21J.244.169; 21J.244.172; 21J.244.175; 21.J.244.240; 21.J.244.244;

Prodrugs of21.L

21.L.228.228; 21.L.228.229; 21.L.228.230; 21.L.228.231; 21.L.228.236; 21.L.228.237; 21.L.228.238; 21.L.228.239; 21.L.228.154; 21.L.228.157; 21.L.228.166; 21.L.228.169; 21.L.228.172; 21.L.228.175; 21.L.228.240; 21.L.228.244; 21.L.229.228; 21.L.229.229; 21.L.229.230; 21.L.229.231; 21.L.229.236; 21.L.229.237; 21.L.229.238; 21.L.229.239;21.L.229.154; 21.L.229.157; 21.L.229.166; 21.L.229.169; 21.L.229.172; 21.L.229.175; 21.L.229.240; 21.L.229.244; 21.L.230.228; 21.L.230.229; 21.L.230.230; 21.L.230.231; 21.L.230.236; 21.L.230.237; 21.L.230.238; 21.L.230.239; 21.L.230.154; 21.L.230.157; 21.L.230.166; 21.L.230.169; 21.L.230.172; 21.L.230.175; 21.L.230.240; 21.L.230.244; 21.L.231.228; 21.L.231.229; 21.L.231.230; 21.L.231.231; 21.L.231.236; 21.L.231.237; 21.L.231.238; 21X.231.239; 21X.231154; 21.L.231.157; 21.L.231.166; 21.L.231.169; 21.L.231.172; 21.L.231.175; 21.L.231.240; 21.L.231.244; 21.L.236.228; 21.L.236.229; 21.L.236.230; 21X.236.231; 21X.236.236; 21X.236.237; 21X.236.238; 21X.236.239; 21X.236.154; 21X.236.157; 21X.236.166; 21X.236.169; 21X.236.172; 21X.236.175; 21X.236.240; 21X.236.244; 21X.237.228; 21X.237.229; 21X.237.230; 21X.237.231; 21X.237.236; 21X.237.237; 21X.237.238; 21X.237.239; 21X.237.154; 21X.237.157; 21X.237.166; 21X.237.169; 21X.237.172; 21X.237.175; 21X.237.240; 21X.237.244; 21X.238.228; 21X.238.229; 21X.238.230; 21X.238.231; 21X.238.236; 21X.238.237; 21X.238.238; 21X.238.239; 21X.238.154; 21X.238.157; 21X.238.166; 21X.238.169; 21X.238.172; 21X.238.175; 21X.238.240; 21X.238.244; 21X.239.228; 21X.239.229; 21X.239.230; 21X.239.231; 21X.239.236; 21X.239.237; 21X.239.238; 21X.239.239; 21X.239.154; 21X.239.157; 21X.239.166; 21X.239.169; 21X.239.172; 21X.239.175; 21X.239.240; 21X.239.244; 21X.154.228; 21X.154.229; 21X.154.230; 21X.154.231; 21X.154.236; 21X.154.237; 21X.154.238; 21X.154.239; 21X.154.154; 21X.154.157; 21X.154.166; 21X.154.169; 21X.154.172; 21X.154.175; 21X.154.240; 21X.154.244; 21X.157.228; 21X.157.229; 21X.157.230; 21X.157.231; 21X.157.236; 21X.157.237; 21X.157.238; 21X.157.239; 21X.157.154; 21X.157.157; 21X.157.166; 21X.157.169; 21X.157.172; 21X.157.175; 21X.157.240; 21X.157.244; 21.L.166.228; 21X.166.229; 21X.166.230; 21X.166.231; 21X.166.236; 21X.166.237; 21X.166.238; 21X.166.239; 21X.166.154; 21X.166.157; 21X.166.166; 21X.166.169; 21X.166.172; 21X.166.175; 21X.166.240; 21X.166.244; 21X.169.228; 21X.169.229; 21X.169.230; 21X.169.231; 21X.169.236; 21X.169.237; 21X.169.238; 21X.169.239; 21X.169.154; 21X.169.157; 21X.169.166; 21X.169.169; 21X.169.172; 21X.169.175; 21X.169.240; 21X.169.244; 21X.172.228; 21X.172.229; 21X.172.230; 21.L.172.231; 21X.172.236; 21X.172.237; 21X.172.238; 21X172.239; 21X172154; 21X172157; 21X172166; 21X172169; 21X172172; 21X172175; 21X172.240; 21X172.244; 21X175.228; 21X175.229; 21X175.230; 21X175.231; 21X175.236; 21X175.237; 21X175.238; 21X175.239; 21X175154; 21X175157; 21X175166; 21X175169; 21X175172; 21X175175; 21X175.240; 21X175.244; 21X.240.228; 21X.240.229; 21X.240.230; 21X.240.231; 21X.240.236; 21.L.24Q.237; 21X.240.238; 21X.240.239; 21X.240154; 21X.240.157; 21X.240166; 21X.240169; 21.L.240.172; 21X.240175; 21X.240.240; 21X.240.244; 21X.244.228; 21X.244.229; 21X.244.230; 21X.244.231; 21X.244.236; 21X.244.237; 21X.244.238; 21X.244.239; 21X.244154; 21X.244157; 21X.244166; 21X.244169; 21X.244.172; 21.L.244175; 21X.244.240; 21X.244.244;

Prodrugs of 21.0

21.O.228.228; 21.O.228.229; 21.O.228.230; 21.O.228.231; 21.O.228.236; 21.O.228.237; 21.O.228.238; 21.O.228.239; 21.O.228154; 21.O.228157; 21.O.228.166; 21.O.228.169; 21.O.228.172; 21.O.228175; 21.O.228.240; 21.O.228.244; 21.O.229.228; 21.O.229.229; 21.O.229.230; 21.O.229.231; 21.O.229.236; 21.O.229.237; 21.O.229.238; 21.O.229.239; 21.O.229.154; 21.O.229157; 21.O.229166; 21.O.229.169; 21.O.229.172; 21.O.229.175; 21.O.229.240; 21.O.229.244; 21.O.230.228; 21.O.230.229; 21.O.230.230; 21.O.230.231; 21.O.230.236; 21.O.230.237; 21.O.230.238; 21.O.230.239; 21.O.230.154; 21.O.230.157; 21.O.230.166; 21.O.230.169; 21.O.230.172; 21.O.230.175; 21.O.230.240; 21.O.230.244; 21.O.231.228; 21.O.231.229; 21.O.231.230; 21.O.231.231; 21.O.231.236; 21.O.231.237; 21.O.231.238; 21.O.231.239; 21.O.231.154; 21.O.231.157; 21.O.231.166; 21.O.231.169; 21.O.231.172; 21.O.231.175; 21.O.231.240; 21.O.231.244; 21.O.236.228; 21.O.236.229; 21.O.236.230; 21.O.236.231; 21.O.236.236; 21.O.236.237; 21.O.236.238; 21.O.236.239; 21.O.236.154; 21.O.236.157; 21.O.236.166; 21.O.236.169; 21.O.236.172; 21.O.236.175; 21.O.236.240; 21.O.236.244; 21.O.237.228; 21.O.237.229; 21.O.237.230; 21.O.237.231; 21.O.237.236; 21.O.237.237; 21.O.237.238; 21.O.237.239; 21.O.237.154; 21.O.237.157; 21.O.237.166; 21.O.237.169; 21.O.237.172; 21.O.237.175; 21.O.237.240; 21.O.237.244; 21.O.238.228; 21.O.238.229; 21.O.238.230; 21.O.238.231; 21.O.238.236; 21.O.238.237; 21.O.238.238; 21.O.238.239; 21.O.238.154; 21.O.238.157; 21.O.238.166; 21.O.238.169; 21.O.238.172; 21.O.238.175; 21.O.238.240; 21.O.238.244; 21.O.239.228; 21.O.239.229; 21.O.239.230; 21.O.239.231; 21.O.239.236; 21.O.239.237; 21.O.239.238; 21.O.239.239; 21.O.239.154; 21.O.239.157; 21.O.239.166; 21.O.239.169; 21.O.239.172; 21.O.239.175; 21.O.239.240; 21.O.239.244; 21.O.154.228; 21.O.154.229; 21.O.154.230; 21.O.154.231; 21.O.154.236; 21.O.154.237; 21.O.154.238; 21.O.154.239; 21.O.154.154; 21.O.154.157; 21.O.154.166; 21.O.154.169; 21.O.154.172; 21.O.154.175; 21.O.154.24Q; 21.O.154.244; 21.O.157.228; 21.O.157.229; 21.O.157.230; 21.O.157.231; 21.O.157.236; 21.O.157.237; 21.O.157.238; 21.O.157.239; 21.O.157.154; 21.O.157.157; 21.O.157.166; 21.O.157.169; 21.O.157.172; 21.O.157.175; 21.O.157.240; 21.O.157.244; 21.O.166.228; 21.O.166.229; 21.O.166.230; 21.O.166.231; 21.O.166.236; 21.O.166.237; 21.O.166.238; 21.O.166.239; 21.O.166.154; 21.O.166.157; 21.O.166.166; 21.O.166.169; 21.O.166.172; 21.O.166.175; 21.O.166.240; 21.O.166.244; 21.O.169.228; 21.O.169.229; 21.O.169.230; 21.0.169.231; 21.O.169.236; 21.O.169.237; 21.O.169.238; 21.O.169.239; 21.O.169.154; 21.O.169.157; 21.O.169.166; 21.O.169.169; 21.O.169.172; 21.O.169.175; 21.O.169.240; 21.O.169.244; 21.O.172.228; 21.O.172.229; 21.O.172.230; 21.O.172.231; 21.O.172.236; 21.O.172.237; 21.O.172.238; 21.O.172.239; 21.O.172.154; 21.O.172.157; 21.O.172.166; 21.O.172.169; 21.O.172.172; 21.O.172.175; 21.O.172.240; 21.O.172.244; 21.O.175.228; 21.O.175.229; 21.O.175.230; 21.O.175.231; 21.O.175.236; 21.O.175.237; 21.O.175.238; 21.O.175.239; 21.O.175.154; 21.O.175.157; 21.O.175.166; 21.O.175.169; 21.O.175.172; 21.O.175.175; 21.O.175.240; 21.O.175.244; 21.O.240.228; 21.O.240.229; 21.O.240.230; 21.O.240.231; 21.O.240.236; 21.O.240.237; 21.O.240.238; 21.O.240.239; 21.O.240.154; 21.O.240.157; 21.O.240.166; 21.O.240.169; 21.O.240.172; 21.O.240.175; 21.O.240.240; 21.O.240.244; 21.O.244.228; 21.O.244.229; 21.O.244.230; 21.O.244.231; 21.O.244.236; 21.O.244.237; 21.O.244.238; 21.O.244.239; 21.O.244.154; 21.O.244.157; 21.O.244.166; 21.O.244.169; 21.O.244.172; 21.O.244.175; 21.O.244.240; 21.O.244.244;

Prodrugs of 21.P 21.P.228.228; 21.P.228.229; 21.P.228.230; 21.P.228.231; 21.P.228.236; 21.P.228.237; 21.P.228.238; 21.P.228.239; 21.P.228.154; 21.P.228.157; 21.P.228.166; 21.P.228.169; 21.P.228.172; 21.P.228.175; 21.P.228.240; 21.P.228.244; 21.P.229.228; 21.P.229.229; 21.P.229.230; 21.P.229.231; 21.P.229.236; 21.P.229.237; 21.P.229.238; 21.P.229.239; 21.P.229.154; 21.P.229.157; 21.P.229.166; 21.P.229.169; 21.P.229.172; 21.P.229.175; 21.P.229.240; 21.P.229.244; 21.P.230.228; 21.P.230.229; 21.P.230.230; 21.P.230.231; 21.P.230.236; 21.P.230.237; 21.P.230.238; 21.P.230.239; 21.P.230.154; 21.P.230.157; 21.P.230.166; 21.P.230.169; 21.P.230.172; 21.P.230.175; 21.P.230.240; 21.P.230.244; 21.P.231.228; 21.P.231.229; 21.P.231.230; 21.P.231.231; 21.P.231.236; 21.P.231.237; 21.P.231.238; 21.P.231.239; 21.P.231.154; 21.P.231.157; 21.P.231.166; 21.P.231.169; 21.P.231.172; 21.P.231.175; 21.P.231.240; 21.P.231.244; 21.P.236.228; 21.P.236.229; 21.P.236.230; 21.P.236.231; 21.P.236.236; 21.P.236.237; 21.P.236.238; 21.P.236.239; 21.P.236.154; 21.P.236.157; 21.P.236.166; 21.P.236.169; 21.P.236.172; 21.P.236.175; 21.P.236.240; 21.P.236.244; 21.P.237.228; 21.P.237.229; 21.P.237.230; 21.P.237.231; 21.P.237.236; 21.P.237.237; 21.P.237.238; 21.P.237.239; 21.P.237.154; 21.P.237.157; 21.P.237.166; 21.P.237.169; 21.P.237.172; 21.P.237.175; 21.P.237.240; 21.P.237.244; 21.P.238.228; 21.P.238.229; 21.P.238.230; 21.P.238.231; 21.P.238.236; 21.P.238.237; 21.P.238.238; 21.P.238.239; 21.P.238.154; 21.P.238.157; 21.P.238.166; 21.P.238.169; 21.P.238.172; 21.P.238.175; 21.P.238.240; 21.P.238.244; 21.P.239.228; 21.P.239.229; 21.P.239.230; 21.P.239.231; 21.P.239.236; 21.P.239.237; 21.P.239.238; 21.P.239.239; 21.P.239.154; 21.P.239.157; 21.P.239.166; 21.P.239.169; 21.P.239.172; 21.P.239.175; 21.P.239.240; 21.P.239.244; 21.P.154.228; 21.P.154.229; 21.P.154.230; 21.P.154.231; 21.P.154.236; 21.P.154.237; 21.P.154.238; 21.P.154.239; 21.P.154.154; 21.P.154.157; 21.P.154.166; 21.P.154.169; 21.P.154.172; 21.P.154.175; 21.P.154.240; 21.P.154.244; 21.P.157.228; 21.P.157.229; 21.P.157.230; 21.P.157.231; 21.P.157.236; 21.P.157.237; 21.P.157.238; 21.P.157.239; 21.P.157.154; 21.P.157.157; 21.P.157.166; 21.P.157.169; 21.P.157.172; 21.P.157.175; 21.P.157.240; 21.P.157.244; 21.P.166.228; 21.P.166.229; 21.P.166.230; 21.P.166.231; 21.P.166.236; 21.P.166.237; 21.P.166.238; 21.P.166.239; 21.P.166.154; 21.P.166.157; 21.P.166.166; 21.P.166.169; 21.P.166.172; 21.P.166.175; 21.P.166.240; 21.P.166.244; 21.P.169.228; 21.P.169.229; 21.P.169.230; 21.P.169.231; 21.P.169.236; 21.P.169.237; 21.P.169.238; 21.P.169.239; 21.P.169.154; 21.P.169.157; 21.P.169.166; 21.P.169.169; 21.P.169.172; 21.P.169.175; 21.P.169.240; 21.P.169.244; 21.P.172.228; 21.P.172.229; 21.P.172.230; 21.P.172.231; 21.P.172.236; 21.P.172.237; 21.P.172.238; 21.P.172.239; 21.P.172.154; 21.P.172.157; 21.P.172.166; 21.P.172.169; 21.P.172.172; 21.P.172.175; 21.P.172.240; 21.P.172.244; 21.P.175.228; 21.P.175.229; 21.P.175.230; 21.P.175.231; 21.P.175.236; 21.P.175.237; 21.P.175.238; 21.P.175.239; 21.P.175.154; 21.P.175.157; 21.P.175.166; 21.P.175.169; 21.P.175.172; 21.P.175.175; 21.P.175.240; 21.P.175.244; 21.P.240.228; 21.P.240.229; 21.P.240.230; 21.P.240.231; 21.P.240.236; 21.P.240.237; 21.P.240.238; 21.P.240.239; 21.P.240.154; 21.P.240.157; 21.P.240.166; 21.P.240.169; 21.P.240.172; 21.P.240.175; 21.P.240.240; 21.P.240.244; 21.P.244.228; 21.P.244.229; 21.P.244.230; 21.P.244.231; 21.P.244.236; 21.P.244.237; 21.P.244.238; 21.P.244.239; 21.P.244.154; 21.P.244.157; 21.P.244.166; 21.P.244.169; 21.P.244.172; 21.P.244.175; 21.P.244.240; 21.P.244.244;

Prodrugs of 21.U 21.U.228.228; 21.U.228.229; 21.U.228.230; 21.U.228.231; 21.U.228.236; 21.U.228.237; 21.U.228.238; 21.U.228.239; 21.U.228.154; 21.U.228.157; 21.U.228.166; 21.U.228.169; 21.U.228.172; 21.U.228.175; 21.U.228.240; 21.U.228.244; 21.U.229.228; 21.U.229.229; 21.U.229.230; 21.U.229.231; 21.U.229.236; 21.U.229.237; 21.U.229.238; 21.U.229.239; 21.U.229.154; 21.U.229.157; 21.U.229.166; 21.U.229.169; 21.U.229.172; 21.U.229.175; 21.U.229.240; 21.U.229.244; 21.U.230.228; 21.U.230.229; 21.U.230.230; 21.U.230.231; 21.U.230.236; 21.U.230.237; 21.U.230.238; 21.U.230.239; 21.U.230.154; 21.U.230.157; 21.U.230.166; 21.U.230.169; 21.U.230.172; 21.U.230.175; 21.U.230.240; 21.U.23Q.244; 21.U.231.228; 21.U.231.229; 21.U.231.230; 21.U.231.231; 21.U.231.236; 21.U.231.237; 21.U.231.238; 21.U.231.239; 21.U.231.154; 21.U.231.157; 21.U.231.166; 21.U.231.169; 21.U.231.172; 21.U.231.175; 21.U.231.240; 21.U.231.244; 21.U.236.228; 21.U.236.229; 21.U.236.230; 21.U.236.231; 21.U.236-236; 21.U.236.237; 21.U.236.238; 21.U.236.239; 21.U.236.154; 21.U.236.157; 21.U.236.166; 21.U.236.169; 21.U.236.172; 21.U.236.175; 21.U.236.240; 21.U.236.244; 21.U.237.228; 21.U.237.229; 21.U.237.230; 21.U.237.231; 21.U.237.236; 21.U.237.237; 21.U.237.238; 21.U.237.239; 21.U.237.154; 21.U.237.157; 21.U.237.166; 21.U.237.169; 21.U.237.172; 21.U.237.175; 21.U.237.240; 21.U.237.244; 21.U.238.228; 21.U.238.229; 21.U.238.230; 21.U.238.231; 21.U.238.236; 21.U.238.237; 21.U.238.238; 21.U.238.239; 21.U.238.154; 21.U.238.157; 21.U.238.166; 21.U.238.169; 21.U.238.172; 21.U.238.175; 21.U.238.240; 21.U.238.244; 21.U..239.228; 21.U.239.229; 21.U.239.230; 21.U.239.231; 21.U.239.236; 21.U.239.237; 21.U.239.238; 21.U.239.239; 21.U.239.154; 21.U.239.157; 21.U..239.166; 21.U.239.169; 21.U.239.172; 21.U.239.175; 21.U.239.240; 21.U.239.244; 21.U.154.228; 21.U.154.229; 21.U.154.230; 21.U.154.231; 21.U.154.236; 21.U.154.237; 21.U.154.238; 21.U.154.239; 21.U.154.154; 21.U.154.157; 21.U.154.166; 21.U.154.169; 21.U.154.172; 21.U.154.175; 21.U.154.240; 21.U.154.244; 21.U.157.228; 21.U.157.229; 21.U.157.230; 21.U.157.231; 21.U.157.236; 21. U.157.237; 21.U.157.238; 21.U.157.239; 21.U.157.154; 21.U.157.157; 21.U.157.166; 21.U.157.169; 21.U.157.172; 21.U.157.175; 21.U.157.240; 21.U.157.244; 21.U.166.228; 21.U.166.229; 21.U.166.230; 21.U.166.231; 21.U.166.236; 21.U.166.237; 21.U.166.238; 21.U.166.239; 21.U.166.154; 21.U.166.157; 21.U.166.166; 21.U.166.169; 21..U.166.172; 21.U.166.175; 21.U.166.240; 21.U.166.244; 21.U.169.228; 21.U.169.229; 21.U.169.230; 21.U.169.231; 21.U.169.236; 21.U.169.237; 21.U.169.238; 21.U.169.239; 21.U.169.154; 21.U.169.157; 21.U.169.166; 21.U.169.169; 21.U.169.172; 21.U.169.175; 21.U.169.240; 21.U.169.244; 21.U.172.228; 21.U.172.229; 21.U.172.230; 21.U.172.231; 21.U .172.236; 21.U.172.237; 21.U.172.238; 21.U.172.239; 21.U.172.154; 21.U.172.157; 21.U.172.166; 21..U ^'.172.169; 21.U.172.172; 21.U.172.175; 21.U.172.240; 21.U.172.244; 21.IJ.175.228; 21.U.175.229; 21.U.175.230; 21.U.175.231; 21.U.175.236; 21.U.175.237; 21.U.175.238; 21.U.175.239; 21.U.175.154; 21.U.175.157; 21.U.175.166; 21.U.175.169; 21.U.175.172; 21.U.175.175; 21.U.175.240; 21.U.175.244; 21.U.240.228; 21.U.240.229; 21.U.240.230; 21.U.240.231; 21.U.240.236; 21.U.240.237; 21.U.240.238; 21.U.240.239; 21.U.240.154; 21.U.240.157; 21.U.240.166; 21.U.240.169; 21.U.240.172; 21.U.240.175; 21.U.240.240; 21.U.240.244; 21.U.244.228; 21.U.244.229; 21.U.244.230; 21.U.244.231; 21.U.244.236; 21.U.244.237; 21.U.244.238; 21.U.244.239; 21.U.244.154; 21.U.244.157; 21.U.244.166; 21.U.244.169; 21.U.244.172; 21.U.244.175; 21.U.244.240; 21.U.244.244;

Prodrugs of 21.CD

21.CD.228.228; 21.CD.228.229; 21.CD.228.230; 21.CD.228.231; 21.CD.228.236; 21.CD.228.237; 21.CD.228.238; 21.CD.228.239; 21.CD.228.154; 21.CD.228.157; 21.CD.228.166; 21.CD.228.169; 21.CD.228.172; 21.CD.228.175; 21.CD.228.240; 21.CD.228.244; 21.CD.229.228; 21.CD.229.229; 21.CD.229.230; 21.CD.229.231; 21.CD.229.236; 21.CD.229.237; 21.CD.229.238; 21.CD.229.239; 21.CD.229.154; 21.CD.229.157; 21.CD.229.166; 21.CD.229.169; 21.CD.229.172; 21.CD.229.175; 21.CD.229.240; 21.CD.229.2U; 21.CD.230.228; 21.CD.230.229; 21.CD.230.230; 21.CD.230.231; 21.CD.230.236; 21.CD.23Q.237; 21.CD.230.238; 21.CD.230.239; 21.CD.230.154; 21.CD.230.157; 21.CD.230.166; 21.CD.230.169; 21.CD.230.172; 21.CP.230.175; 21.CD.230.240; 21.CD.230.244; 21.CD.231.228; 21. CD..231.229; 21.CD.231.230; 21.CD.231.231; 21.CD.231.236; 21.CD.231.237; 21.CD.231.238; 21.CD.231.239; 21.CD.231.154; 21.CD.231.157; 21.CD.231.166; 21.CD.231.169; 21.CD.231.172; 21.CD.231.175; 21.CD.231.240; 21.CD.231.244; 21.CD.236.228; 21.CD.236.229; 21.CD.236.230; 21. CD.236.231; 21.CD.236.236; 21.CD.236.237; 21.CD.236.238; 21.CD.236.239; 21.CD.236.154; 21.CD.236.157; 21.CD.236.166; 21.CD.236.169; 21.CD.236.172; 21.CD.236.175; 21.CD.236.240; 21.CD.236.244; 21.CD.237.228; 21.CD.237.229; 21.CD.237.230; 21.CD.237.231; 21.CD.237.236; 21.CD.237.237; 21.CD.237.238; 21.CD.237.239; 21.CD.237.154; 21.CD.237.157; 21.CD.237.166; 21.CD.237.169; 21.CD.237.172; 21.CD.237.175; 21.CD.237.240; 21.CD.237.244; 21.CD.238.228; 21.CD.238.229; 21.CD.238.230; 21.CD.238.231; 21.CD.238.236; 21.CD.238.237; 21.CD.238.238; 21.CD.238.239; 21.CD.238.154; 21.CD.238.157; 21.CD.238.166; 21.CD.238.169; 21.CD.238.172; 21.CD.238.175; 21.CD.238.240; 21.CD.238.244; 21.CD.239.228; 21.CD.239.229; 21.CD.239.230; 21.CD.239.231; 21.CD.239.236; 21.CD.239.237; 21.CD.239.238; 21.CD.239.239; 21.CD.239.154; 21.CD.239.157; 21.CD.239.166; 21.CD.239.169; 21. CD.239.172; 21.CD.239.175; 21.CD.239.240; 21.CD.239.244; 21.CD.154.228; 21.CD.154.229; 21.CD.154.230; 21.CD.154.231; 21.CD.154.236; 21.CD.154.237; 21.CD.154.238; 21.CD.154.239; 21.CD.154.154; 21.CD.154.157; 21.CD.154.166; 21.CD.154.169; 21.CD.154.172; 21.CD.154.175; 21.CD.154.240; 21.CD.154.244; 21.CD.157.228; 21.CD.157.229; 21.CD.157.230; 21.CD.157.231; 21.CD.157.236; 21.CD.157.237; 21.CD.157.238; 21.CD.157.239; 21.CD.157.154; 21.CD.157.157; 21.CD.157.166; 21.CD.157.169; 21.CD.157.172; 21.CD.157.175; 21.CD.157.240; 21.CD.157.244; 21.CD.166.228; 21.CD.166.229; 21.CD.166.230; 21.CD.166.231; 21.CD.166.236; 21.CD.166.237; 21.CD.166.238; 21.CD.166.239; 21.CD.166.154; 21.CD.166.157; 21.CD.166.166; 21.CD.166.169; 21. CD.166.172; 21.CD.166.175; 21.CD.166.240; 21.CD.166.244; 21.CD.169.228; 21.CD.169.229; 21.CD.169.230; 21.CD.169.231; 21.CD.169.236; 21.CD.169.237; 21.CD.169.238; 21.CD.169.239; 21.CD.169.154; 21.CD.169.157; 21.CD.169.166; 21.CD.169.169; 21.CD.169.172; 21.CD.169.175; 21.CD.169.240; 21.CD.169.244; 21.CD.172.228; 21. CD.172229; 21.CD.172.230; 21.CD.172.231; 21. CO.172.236; 21.CLU72.237; 21.CD.172.238; 21. CD.172.239; 21.CD.172.154; 21. CO.172.157; 21.CP.172.166; 21. CD.172.169; 21. CD.172.172; 21.CD.172.175; 21.CD.172.240; 21.CD.172.244; 21.CD.175.228; 21.CD.175.229; 21.CD.175.230; 21.CD.175.231; 21.CD.175.236; 21.CD.175.237; 21.CD.175.238; 21.CD.175.239; 21.CD.175.154; 21.CD.175.157; 21.CD.175.166; 21.CD.175.169; 21.CD.175.172; 21.CD.175.175; 21.CD.175.240; 21.CD.175.244; 21.CD.240.228; 21.CD.240.229; 21.CD.240.230; 21.CD.240.231; 21.CD.240.236; 21.CD.240.237; 21.CD.240.238; 21.CU240.239; 21.CD.240.154; 21.CD.240.157; 21.CD.240.166; 21.CD.240.169; 21. CD.2AQ.172; 21.CD.240.175; 21.CD.240.240; 21.CD.240.244; 21.CD.244.228; 21.CD.244.229; 21.CD.244.230; 21.CD.244.231; 21.CD.244.236; 21.CD.244.237; 21.CD.244.238; 21.CD.244.239; 21.CD.244.154; 21.CD.244.157; 21.CD.244.166; 21.CD.244.169; 21.CD.244.172; 21.CD.244.175; 21.CD.244.240; 21.CD.244.244;

Prodrugs of 21.EB

21.EB.228.228; 21.EB.228.229; 21.EB.228.230; 21.EB.228.231; 21.EB.228.236; 21.EB.228.237; 21.EB.228.238; 21.EB.228.239; 21.EB.228.154; 21.EB.228.157; 21.EB.228.166; 21.EB.228.169; 21.EB.228.172; 21.EB.228.175; 21. EB.228.240; 21.EB.228.244; 21.EB.229.228; 21.EB.229.229; 21.EB.229.230; 21.EB.229.231; 21.EB.229.236; 21.EB.229.237; 21.EB.229.238; 21.EB.229.239; 21.EB.229.154; 21.EB.229.157; 21.EB.229.166; 21.EB.229.169; 21.EB.229.172; 21.EB.229.175; 21.EB.229.240; 21.EB.229.244; 21.EB .230.228; 21.EB.230.229; 21.EB.230.230; 21.EB.230.231; 21.EB.230.236; 21.EB.230.237; 21.EB.230.238; 21.EB.230.239; 21.EB.230.154; 21.EB.230.157; 21.EB.230.166; 21.EB.230.169; 21.EB.230.172; 21.EB.230.175; 21.EB.230.240; 21.EB.230.244; 21.EB.231.228; 21.EB.231.229; 21.EB.231.230; 21.EB.231.231; 21.EB.231.236; 21.EB.231.237; 21.EB.231.238; 21.EB.231.239; 21.EB.231.154; 21..EB .231.157; 21.EB.231.166; 21.EB.231.169; 21.EB.231.172; 21.EB.231.175; 21.EB.231.240; 21.EB.231.244; 21.EB.236.228; 21.EB.236.229; 21.EB.236.230; 21.EB.236.231; 21.EB.236.236; 21.EB.236.237; 21.EB.236.238; 21.EB.236.239; 21.EB .236.154; 21.EB.236.157; 21.EB.236.166; 21.EB.236.169; 21.EB.236.172; 21.EB.236.175; 21.EB.236.240; 21.EB.236.244; 21.EB.237.228; 21.EB.237.229; 21.EB.237.230; 21.EB.237.231; 21. ΕB.237236; 21.EB.237.237; 21.EB.237.238; 21.EB.237.239; 21.EB.237.154; 21.EB.237.157; 21.EB.237.166; 21.EB.237.169; 21.EB.237.172; 21.EB.237.175; 21.EB.237.240; 21.EB.237.244; 21.EB.238.228; 21.EB.238.229; 21.EB.238.230; 21.EB.238.231; 21.EB.238.236; 21.EB.238.237; 21.EB.238.238; 21.EB.238.239; 21.EB.238.154; 21.EB.238.157; 21.EB.238.166; 21.EB.238.169; 21.EB.238.172; 21.EB.238.175; 21.EB.238.240; 21.EB.238.244; 21.EB.239.228; 21.EB.239.229; 21.EB.239.230; 21.EB.239.231; 21.EB.239.236; 21.EB.239.237; 21.EB.239.238; 21. EB.239.239; 21.EB.239.154; 21.EB.239.157; 21.EB.239.166; 21.EB.239.169; 21.EB.239.172; 21.EB.239.175; 21.EB.239.240; 21.EB.239.244; 21.EB.154.228; 21.EB.154.229; 21.EB.154.230; 21.EB.154.231; 21.EB.154.236; 21.EB.154.237; 21.EB.154.238; 21.EB.154.239; 21.EB.154.154; 21.EB.154.157; 21.EB.154.166; 21.EB.154.169; 21.EB.154.172; 21.EB.154.175; 21. EB.154.240; 21. EB.154.244; 21.EB.157.228; 21.EB.157.229; 21.EB.157.230; 21.EB.157.231; 21.EB.157.236; 21.EB.157.237; 21.EB.157.238; 21.EB.157.239; 21.EB.157.154; 21.EB.157.157; 21.EB.157.166; 21.EB.157.169; 21.EB.157.172; 21.EB.157.175; 21.EB.157.240; 21.EB.157.244; 21.EB.166.228; 21.EB.166.229; 21.EB.166.230; 21.EB.166.231; 21.EB.166.236; 21.EB.166.237; 21.EB.166.238; 21.EB.166.239; 21.EB.166.154; 21.EB.166.157; 21.EB.166.166; 21.EB.166.169; 21.EB.166.172; 21.EB.166.175; 21.EB.166.240; 21.EB.166.244; 21.EB.169.228; 21.EB.169.229; 21.EB.169.230; 21.EB.169.231; 21.EB.169.236; 21.EB.169.237; 21.EB.169.238; 21.EB.169.239; 21.EB.169.154; 21.EB.169.157; 21.EB.169.166; 21.EB.169.169; 21.EB.169.172; 21.EB.169.175; 21.EB.169.240; 21.EB.169.244; 21.EB.172.228; 21.EB.172.229; 21.EB.172.230; 21.EB.172.231; 21..EB.172.236; 21.EB.172.237; 21.EB.172.238; 21.EB.172.239; 21.EB.172.154; 21.EB.172.157; 21.EB.172.166; 21.EB.172.169; 21.EB.172.172; 21.EB.172.175; 21.EB.172.240; 21.EB.172.244; 21.EB.175.228; 21.EB.175.229; 21.EB.175.230; 21.EB.175.231; 21.EB.175.236; 21.EB.175.237; 21.EB.175.238; 21.EB.175.239; 21.EB.175.154; 21.EB.175.157; 21.EB.175.166; 21.EB.175.169; 21.EB.175.172; 21.EB.175.175; 21.EB.175.240; 21.EB.175.244; 21.EB.240.228; 21.EB.240.229; 21.EB.240.230; 21.EB.240.231; 21.EB.240.236; 21.EB.240.237; 21.EB.240.238; 21.EB.240.239; 21.EB.240.154; 21.EB.240.157; 21.EB.240.166; 21.EB.240.169; 21.EB.240.172; 21.EB.240.175; 21.EB.240.240; 21.EB.240.244; 21.EB.244.228; 21. EB.244.229; 21.EB.244.230; 21.EB.244.231; 21. EB .244.236; 21.EB.244.237; 21.EB.244.238; 21.EB.244.239; 21.EB.244.154; 21.EB.244.157; 21.EB.244.166; 21.EB.244.169; 21.EB.244.172; 21.EB.244.175; 21.EB.244.240; 21.EB.244.244;

Prodrugs of 22.B

22.B.228.228; 22.B.228.229; 22.B.228.230; 22.B.228.231; 22.B.228.236; 22.B.228.237; 22.B.228.238; 22.B.228.239; 22.B.228.154; 22.B.228.157; 22.B.228.166; 22.B.228.169; 22.B.228.172; 22.B.228.175; 22.B.228.240; 22.B.228.244; 22.B.229.228; 22.B.229.229; 22.B.229.230; 22.B.229.231; 22.B.229.236; 22.B.229.237; 22.B.229.238; 22.B.229.239; 22.B.229.154; 22.B.229.157; 22.B.229.166; 22.B.229.169; 22.B.229.172; 22.B.229.175; 22.B.229.240; 22.B.229.244; 22.B.230.228; 22.B.230.229; 22.B.230.230; 22.B.230.231; 22.B.230.236; 22.B.230.237; 22.B.230.238; 22.B.230.239; 22.B.230.154; 22.B.230.157; 22.B.230.166; 22.B.230.169; 22.B.230.172; 22.B.230.175; 22.B.230.240; 22.B.230.244; 22.B.231.228; 22.B.231.229; 22.B.231.230; 22.B.231.231; 22.B.231.236; 22.B.231.237; 22.B.231.238; 22.B.231.239; 22.B.231.154; 22.B.231.157; 22.B.231.166; 22.B.231.169; 22.B.231.172; 22.B.231.175; 22.B.231.240; 22.B.231.244; 22.B.236.228; 22.B.236.229; 22.B.236.230; 22.B.236.231; 22.B.236.236; 22.B.236.237; 22.B.236.238; 22.B.236.239; 22.B.236.154; 22.B.236.157; 22.B.236.166; 22.B.236.169; 22.B.236.172; 22.B.236.175; 22.B.236.240; 22.B.236.244; 22.B.237.228; 22.B.237.229; 22.B.237.230; 22.B.237.231; 22.B.237.236; 22.B.237.237; 22.B.237.238; 22.B.237.239; 22.B.237.154; 22.B.237.157; 22.B.237.166; 22.B.237.169; 22.B.237.172; 22.B.237.175; 22.B.237.240; 22.B.237.244; 22.B.238.228; 22.B.238.229; 22.B.238.230; 22.B.238.231; 22.B.238.236; 22.B.238.237; 22.B.238.238; 22.B.238.239; 22.B.238.154; 22.B.238.157; 22.B.238.166; 22.B.238.169; 22.B.238.172; 22.B.238.175; 22.B.238.240; 22.B.238.244; 22.B.239.228; 22.B.239.229; 22.B.239.230; 22.B.239.231; 22.B.239.236; 22.B.239.237; 22.B.239.238; 22.B.239.239; 22.B.239.154; 22.B.239.157; 22.B.239.166; 22.B.239.169; 22.B.239.172; 22.B.239.175; 22.B.239.240; 22.B.239.244; 22.B.154.228; 22.B.154.229; 22.B.154.230; 22.B.154.231; 22.B.154.236; 22.B.154.237; 22.B.154.238; 22.B.154.239; 22.B.154.154; 22.B.154.157; 22.B.154.166; 22.B.154.169; 22.B.154.172; 22.B.154.175; 22.B.154.240; 22.B.154.244; 22.B.157.228; 22.B.157.229; 22.B.157.230; 22.B.157.231; 22.B.157.236; 22.B.157.237; 22.B.157.238; 22.B.157.239; 22.B.157.154; 22.B.157.157; 22.B.157.166; 22.B.157.169; 22.B.157.172; 22.B.157.175; 22.B.157.240; 22.B.157.244; 22.B.166.228; 22.B.166.229; 22.B.166.230; 22.B.166.231; 22.B.166.236; 22.B.166.237; 22.B.166.238; 22.B.166.239; 22.B.166.154; 22.B.166.157; 22.B.166.166; 22.B.166.169; 22.B.166.172; 22.B.166.175; 22.B.166.240; 22.B.166.244; 22.B.169.228; 22.B.169.229; 22.B.169.230; 22.B.169.231; 22.B.169.236; 22.B.169.237; 22.B.169.238; 22.B.169.239; 22.B.169.154; 22.B.169.157; 22.B.169.166; 22.B.169.169; 22.B.169.172; 22.B.169.175; 22.B.169.240; 22.B.169.244; 22.B.172.228; 22.BΪ72.229; 22.B.172.230; 22.B.172.231; 22.B.172.236; 22.B.172.237; 22.B.172.238; 22.B.172.239; 22.B.172.154; 22.B.172.157; 22.B.172.166; 22.B.172.169; 22.B.172.172; 22.B.172.175; 22.B.172.240; 22.B.172.244; 22.B.175.228; 22.B.175.229; 22.B.175.230; 22.B.175.231; 22.B.175.236; 22.B.175.237; 22.B.175.238; 22.B.175.239; 22.B.175.154; 22.B.175.157; 22.B.175.166; 22.B.175.169; 22.B.175.172; 22.B.175.175; 22.B.175.240; 22.B.175.244; 22.B.240.228; 22.B.240.229; 22.B.240.230; 22.B.240.231; 22.B.240.236; 22.B.24Q.237; 22.B.240.238; 22.B.240.239; 22.B.240.154; 22.B.240.157; 22.B.240.166; 22.B.240.169; 22.B.240.172; 22.B.240.175; 22.B.240.240; 22.B.240.244; 22.B.244.228; 22.B.244.229; 22.B.244.230; 22.B.244.231; 22.B.244.236; 22.B.244.237; 22.B.244.238; 22.B.244.239; 22.B.244.154; 22.B.244.157; 22.B.244.166; 22.B.244.169; 22.B.244.172; 22.B.244.175; 22.B.244.240; 22.B.244.244;

Prodrugs of 22.D

22.D.228.228; 22.D.228.229; 22.D.228.230; 22.D.228.231; 22.D.228.236; 22.D.228.237; 22.D.228.238; 22.D.228.239; 22.D.228.154; 22.D.228.157; 22.D.228.166; 22.D.228.169; 22.D.228.172; 22.D.228.175; 22.D.228.240; 22.D.228.244; 22.D.229.228; 22.D.229.229; 22.D.229.230; 22.D.229.231; 22.D.229.236; 22.D.229.237; 22.D.229.238; 22.D.229.239; 22.D.229.154; 22.D.229.157; 22.D.229.166; 22.D.229.169; 22.D.229.172; 22.D.229.175; 22.D.229.240; 22.D.229.244; 22.D.230.228; 22.D.230.229; 22.D.230.230; 22.D.230.231; 22.D.230.236; 22.D.230.237; 22.D.230.238; 22.D.230.239; 22.D.230.154; 22.D.230.157; 22.D.230.166; 22.D.230.169; 22.D.230.172; 22.D.230.175; 22.D.230.240; 22.D.230.244; 22.D.231.228; 22.D.231.229; 22.D.231.230; 22.D.231.231; 22.D.231.236; 22.D.231.237; 22.D.231.238; 22.D.231.239; 22.D.231.154; 22.D.231.157; 22.D.231.166; 22.D.231.169; 22.D.231.172; 22.D.231.175; 22.D.231.240; 22.D.231.244; 22.D.236.228; 22.D.236.229; 22.D.236.230; 22.D.236.231; 22.D.236.236; 22.D.236.237; 22.D.236.238; 22.D.236.239; 22.D.236.154; 22.D.236.157; 22.D.236.166; 22.D.236.169; 22.D.236.172; 22.D.236.175; 22.D.236.240; 22.D.236.244; 22.D.237.228; 22.D.237.229; 22.D.237.230; 22.D.237.231; 22.D.237.236; 22.D.237.237; 22.D.237.238; 22.D.237.239; 22.D.237.154; 22.D.237.157; 22.D.237.166; 22.D.237.169; 22.D.237.172; 22.D.237.175; 22.D.237.240; 22.D.237.244; 22.D.238.228; 22.D.238.229; 22.D.238.230; 22.D.238.231; 22.D.238.236; 22.D.238.237; 22.D.238.238; 22.D.238.239; 22.D.238.154; 22.D.238.157; 22.D.238.166; 22.D.238.169; 22.D.238.172; 22.D.238.175; 22.D.238.240; 22.D.238.244; 22.D.239.228; 22.D.239.229; 22.D.239.230; 22.D.239.231; 22.D.239.236; 22.D.239.237; 22.D.239.238; 22.D.239.239; 22.D.239.154; 22.D.239.157; 22.D.239.166; 22.D.239.169; 22.D.239.172; 22.D.239.175; 22.D.239.24Q; 22.D.239.244; 22.D.154.228; 22.D.154.229; 22.D.154.230; 22.D.154.231; 22.D.154.236; 22.D.154.237; 22.D.154.238; 22.D.154.239; 22.D.154.154; 22.D.154.157; 22.D.154.166; 22.D.154.169; 22.D.154.172; 22.D.154.175; 22.D.154.24Q; 22.D.154.244; 22.D.157.228; 22.D.157.229; 22.D.157.230; 22.D.157.231; 22.D.157.236; 22.D.157.237; 22.D.157.238; 22.D.157.239; 22.D.157.154; 22.D.157.157; 22.D.157.166; 22.D.157.169; 22.D.157.172; 22.D.157.175; 22.D.157.240; 22.D.157.244; 22.D.166.228; 22.D.166.229; 22.D.166.230; 22.D.166.231; 22.D.166.236; 22.D.166.237; 22.D.166.238; 22.D.166.239; 22.D.166.154; 22.D.166.157; 22.D.166.166; 22.D.166.169; 22.D.166.172; 22.D.166.175; 22.D.166.240; 22.D.166.244; 22.D.169.228; 22.D.169.229; 22.D.169.230; 22.D.169.231; 22.U169.236; 22.D.169.237; 22.D.169.238; 22.D.169.239; 22.D.169.154; 22.D.169.157; 22.D.169.166; 22.D.169.169; 22.D.169.172; 22.D.169.175; 22.D.169.240; 22.D.169.244; 22.D.172.228; 22.D.172.229; 22.D.172.230; 22.D.172.231; 22.D.172.236; 22.D.172.237; 22.D.172.238; 22.D.172.239; 22.D.172.154; 22.D.172.157; 22.D.172.166; 22.D.172.169; 22.D.172.172; 22.D.172.175; 22.D.172.240; 22.D.172.244; 22.D.175.228; 22.D.175.229; 22.D.175.230; 22.D.175.231; 22.D.175.236; 22.P.175.237; 22.D.175.238; 22.D.175.239; 22.D.175.154; 22.D.175.157; 22.D.175.166; 22.D.175.169; 22.D.175.172; 22.D.175.175; 22.D.175.240; 22.D.175.244; 22.D.240.228; 22.D.240.229; 22.D.240.230; 22.D.240.231; 22.D.240.236; 22.D.240.237; 22.D.24Q.238; 22.D.240.239; 22.D.240.154; 22.D.240.157; 22.D.240.166; 22.D.240.169; 22.D.240.172; 22.D.240.175; 22.D.240.240; 22.D.240.244; 22.D.244.228; 22.D.244.229; 22.D.244.230; 22.D.244.231; 22.D.244.236; 22.D.244.237; 22.D.244.238; 22.ID.244.239; 22.D.244.154; 22.D.244.157; 22.D.244.166; 22.D.244.169; 22.D.244.172; 22.D.244.175; 22.D.244.240; 22.D.244.244;

Prodrugs of 22.AB

22.AB.228.228; 22.AB.228.229; 22.AB.228.230; 22.AB.228.231; 22.AB.228.236; 22.AB.228.237; 22.AB.228.238; 22.AB.228.239; 22.AB.228.154; 22.AB.228.157; 22.AB.228.166; 22.AB.228.169; 22.AB.228.172; 22.AB.228.175; 22.AB.228.240; 22.AB.228.244; 22.AB.229.228; 22.AB.229.229; 22.AB.229.230; 22.AB.229.231; 22.AB.229.236; 22.AB.229.237; 22.AB.229.238; 22.AB.229.239; 22.AB.229.154; 22.AB.229.157; 22.AB.229.166; 22.AB.229.169; 22.AB.229.172; 22.AB.229.175; 22.AB.229.240; 22.AB.229.244; 22.AB.230.228; 22. AB.230.229; 22.AB.230.230; 22.AB.230.231; 22.AB.230.236; 22.AB.230.237; 22.AB.230.238; 22.AB.230.239; 22.AB.230.154; 22.AB.23Q.157; 22.AB.23Q.166; 22.AB.230.169; 22.AB.230.172; 22.AB.230.175; 22.AB.230.240; 22.AB.230.244; 22.AB.231.228; 22.AB.231.229; 22.AB.231.230; 22.AB.231.231; 22. AB .231.236; 22.AB.231.237; 22. AB .231.238; 22.AB.231.239; 22.AB.231.154; 22.AB.231.157; 22.AB.231.166; 22.AB.231.169; 22.AB.231.172; 22.AB.231.175; 22.AB.231.240; 22.AB.231.244; 22.AB.236.228; 22.AB.236.229; 22.AB.236.230; 22.AB.236.231; 22.AB.236.236; 22.AB.236.237; 22.AB.236.238; 22.AB.236.239; 22.AB.236.154; 22.AB.236.157; 22.AB.236.166; 22.AB.236.169; 22.AB.236.172; 22.AB.236.175; 22.AB.236.240; 22.AB.236.244; 22.AB.237.228; 22. AB.237.229; 22.AB.237.230; 22.AB.237.231; 22.AB.237.236; 22.AB.237.237; 22.AB.237.238; 22.AB.237.239; 22.AB.237.154; 22.AB.237.157; 22.AB.237.166; 22.AB.237.169; 22.AB.237.172; 22.AB.237.175; 22.AB.237.240; 22.AB.237.244; 22. AB.238.228; 22.AB.238.229; 22.AB.238.230; 22.AB.238.231; 22.AB.238.236; 22.AB.238.237; 22.AB.238.238; 22.AB.238.239; 22.AB.238.154; 22.AB.238.157; 22.AB.238.166; 22.AB.238.169; 22.AB.238.172; 22.AB.238.175; 22.AB.238.240; 22.AB.238.244; 22.AB.239.228; 22.AB.239.229; 22.AB.239.230; 22.AB.239.231; 22.AB.239.236; 22.AB.239.237; 22.AB.239.238; 22.AB.239.239; 22.AB.239.154; 22.AB.239.157; 22.AB.239.166; 22.AB.239.169; 22.AB.239.172; 22.AB.239.175; 22. AB.239.240; 22.AB.239.244; 22.AB.154.228; 22.AB.154.229; 22.AB.154.230; 22.AB.154.231; 22.AB.154.236; 22.AB.154.237; 22.AB.154.238; 22.AB.154.239; 22.AB.154.154; 22.AB.154.157; 22.AB.154.166; 22.AB.154.169; 22.AB.154.172; 22.AB.154.175; 22.AB.154.240; 22.AB.154.244; 22.AB.157.228; 22.AB.157.229; 22.AB.157.230; 22.AB.157.231; 22.AB.157.236; 22.AB.157.237; 22.AB.157.238; 22.AB.157.239; 22.AB.157.154; 22.AB.157.157; 22.AB.157.166; 22.AB.157.169; 22.AB.157.172; 22.AB.157.175; 22.AB.157.240; 22.AB.157.244; 22.AB.166.228; 22.AB.166.229; 22.AB.166.230; 22.AB.166.231; 22.AB.166.236; 22.AB.166.237; 22.AB.166.238; 22.AB.166.239; 22.AB.166.154; 22.AB.166.157; 22.AB.166.166; 22.AB.166.169; 22.AB.166.172; 22.AB.166.175; 22.AB.166.240; 22.AB.166.244; 22. AB.169.228; 22.AB.169.229; 22.AB.169.230; 22.AB.169.231; 22.AB.169.236; 22.AB.169.237; 22.AB.169.238; 22.AB.169.239; 22.AB.169.154; 22.AB.169.157; 22.AB.169.166; 22.AB.169.169; 22.AB.169.172; 22.AB.169.175; 22.AB.169.240; 22.AB.169.244; 22.AB.172.228; 22.AB.172.229; 22.AB.172.230; 22.AB.172.231; 22.AB.172.236; 22.AB.172.237; 22.AB.172.238; 22.AB.172.239; 22.AB.172.154; 22.AB.172.157; 22.AB.172.166; 22.AB.172.169; 22.AB.172.172; 22.AB.172.175; 22.AB.172.240; 22.AB.172.244; 22. AB.175.228; 22.AB.175.229; 22.AB.175.230; 22.AB.175.231; 22.AB.175.236; 22.AB.175.237; 22.AB.175.238; 22.AB.175.239; 22.AB.175.154; 22.AB.175.157; 22.AB.175.166; 22.AB.175.169; 22.AB.175.172; 22.AB.175.175; 22.AB.175.240; 22. AB.175.244; 22.AB.240.228; 22.AB.240.229; 22.AB.240.230; 22.AB.240.231; 22.AB.240.236; 22.AB.240.237; 22.AB.240.238; 22.AB.240.239; 22.AB.240.154; 22.AB.240.157; 22.AB.240.166; 22.AB.240.169; 22.AB.240.172; 22.AB.240.175; 22.AB.240.240; 22.AB.240.244; 22.AB.244.228; 22.AB.244.229; 22.AB.244.230; 22.AB.244.231; 22.AB.244.236; 22.AB.244.237; 22.AB.244.238; 22.AB.244.239; 22.AB.244.154; 22.AB.244.157; 22.AB.244.166; 22.AB.244.169; 22.AB.244.172; 22.AB.244.175; 22.AB.244.240; 22.AB.244.244;

Prodrugs of 22.BI

22.BI.228.228; 22.BL228.229; 22.BI.228.230; 22.BI.228.231; 22.BI.228.236; 22.BI.228.237; 22.BI.228.238; 22.BI.228.239; 22.BI.228.154; 22.BI.228.157; 22.BI.228.166; 22.BI.228.169; 22.BI.228.172; 22.BI.228.175; 22.BL228.240; 22.BI.228.244; 22.BI.229.228; 22.BI.229.229; 22.BI.229.230; 22.BI.229.231; 22.BI.229.236; 22.BI.229.237; 22.BI.229.238; 22.BI.229.239; 22.BI.229.154; 22.BI.229.157; 22.BI.229.166; 22.BI.229.169; 22.BI.229.172; 22.BI.229.175; 22.BI.229.240; 22.BI.229.244; 22.BI.230.228; 22.BI.230.229; 22.BI.230.230; 22.BI.230.231; 22.BI.230.236; 22.BI.23Q.237; 22.BI.230.238; 22.BI.230.239; 22.BI.230.154; 22.BI.230.157; 22.BI.230.166; 22.BI.230.169; 22.BI.230.172; 22.BI.230.175; 22.BI.230.240; 22.BI.230.244; 22.BI.231.228; 22.BI.231.229; 22.BI.231.230; 22.BI.231.231; 22.BI.231.236; 22.BI.231.237; 22.BI.231.238; 22.BI.231.239; 22.BI.231.154; 22.BI.231.157; 22.BI.231.166; 22.BI.231.169; 22.BI.231.172; 22.BI.231.175; 22.BI.231.240; 22.BI.231.244; 22.BI.236.228; 22.BI.236.229; 22.BI.236.230; 22.BI.236.231; 22.BI.236.236; 22.BI.236.237; 22.BI.236.238; 22.BI.236.239; 22.BI.236.154; 22.BI.236.157; 22.BI.236.166; 22.BI.236.169; 22.BI.236.172; 22.BI.236.175; 22.BI.236.240; 22.BI.236.244; 22.BI.237.228; 22.BI.237.229; 22.BI.237.230; 22.BI.237.231; 22.BI.237.236; 22.BI.237.237; 22.BI.237.238; 22.BI.237.239; 22.BI.237.154; 22.BI.237.157; 22.BI.237.166; 22.BI.237.169; 22.BI.237.172; 22.BI.237.175; 22.BI.237.240; 22.BI.237.244; 22.BI.238.228; 22.BI.238.229; 22.BI.238.230; 22.BI.238.231; 22.BI.238.236; 22.BI.238.237; 22.BI.238.238; 22.BI.238.239; 22.BI.238.154; 22.BI.238.157; 22.BL238.166; 22.BL238.169; 22.BI.238.172; 22.BI.238.175; 22.BI.238.240; 22.BI.238.244; 22.BI.239.228; 22.BI.239.229; 22.BI.239.230; 22.BI.239.231; 22.BI.239.236; 22.BI.239.237; 22.BI.239.238; 22.BI.239.239; 22.BI.239.154; 22.BI.239.157; 22.BI.239.166; 22.BI.239.169; 22.BI.239.172; 22.BI.239.175; 22.BI.239.240; 22.BI.239.244; 22.BI.154.228; 22.BI.154.229; 22.BI.154.230; 22.BI.154.231; 22.BI.154.236; 22.BI.154.237; 22.BI.154.238; 22.BI.154.239; 22.BI.154.154; 22.BI.154.157; 22.BI.154.166; 22.BI.154.169; 22.BI.154.172; 22.BI.154.175; 22.BI.154.240; 22.BI.154.244; 22.BI.157.228; 22.BI.157.229; 22.BI.157.230; 22.BI.157.231; 22.BI.157.236; 22.BI.157.237; 22.BI.157.238; 22.BI.157.239; 22.BI.157.154; 22.BI.157.157; 22.BI.157.166; 22.BI.157.169; 22.BI.157.172; 22.BI.157.175; 22.BI.157.24Q; 22.BI.157.244; 22.BI.166.228; 22.BI.166.229; 22.BI.166.230; 22.BI.166.231; 22.BI.166.236; 22.BI.166.237; 22.BI.166.238; 22.BI.166.239; 22.BI.166.154; 22.BI.166.157; 22.BI.166.166; 22.BI.166.169; 22.BI.166-172; 22.BI.166.175; 22.BI.166.240; 22.BI.166.244; 22.BI.169.228; 22.BI.169.229; 22.BI.169.230; 22.BI.169.231; 22.BI.169.236; 22.BI.169.237; 22.BI.169.238; 22.BI.169.239; 22.BI.169.154; 22.BI.169.157; 22.BI.169.166; 22.BL169.169; 22.BI.169.172; 22.BI.169.175; 22.BI.169.240; 22.BI.169.244; 22.BI.172.228; 22.BL172.229; 22.BL172.230; 22.BI.172.231; 22.BI.172.236; 22.BI.172.237; 22.BI.172.238; 22.BI.172.239; 22.BI.172.154; 22.BI.172.157; 22.BI.172.166; 22.BI.172.169; 22.BI.172.172; 22.BI.172.175; 22.BI.172.240; 22.BI.172.244; 22.BI.175.228; 22.BI.175.229; 22.BI.175.230; 22.BI.175.231; 22.BI.175.236; 22.BI.175.237; 22.BI.175.238; 22.BI.175.239; 22.BI.175.154; 22.BI.175.157; 22.BI.175.166; 22.BI.175.169; 22.BI.175.172; 22.BI.175.175; 22.BI.175.240; 2231.175.2U; 22.BI.240.228; 22.BI.240.229; 22.BI.240.230; 22.BI.240.231; 22.BI.240.236; 22.BI.240.237; 22.BI.240.238; 22.BI.240.239; 22.BI.24Q.154; 22.BI.240.157; 22.BI.240.166; 22.BI.240.169; 22.BI.240.172; 22.BI.240.175; 22.BI.240.240; 22.BI.240.244; 22.BI.244.228; 22.BI.244.229; 22.BI.244.230; 22.BI.244.231; 22.BI.244.236; 22.BI.244.237; 22.BI.244.238; 22.BI.244.239; 22.BI.244.154; 22.BI.244.157; 22.BI.244.166; 22.BI.244.169; 22.BI.244.172; 22.BI.244.175; 22.BI.244.240; 22.BI.244.244; Prodrugs of22.1

22.1.228.228; 22.1.228.229; 22.1.228.230; 22.1.228.231; 22.1.228.236; 22.1.228.237; 22.1.228.238; 22.1.228.239; 22.1.228.154; 22.1.228.157; 22.1.228.166; 22.1.228.169; 22.1.228.172; 22.1.228.175; 22.1.228.240; 22.1.228.244; 22.1.229.228; 22.1.229.229; 22.1.229.230; 22.1.229.231; 22.1.229.236; 22.1.229.237; 22.1.229.238; 22.1.229.239; 22.1.229.154; 22.1.229.157; 22.1.229.166; 22.1.229.169; 22.1.229.172; 22.1.229.175; 22.1.229.240; 22.1.229.244; 22.1.230.228; 22.1.230.229; 22.1.230.230;22.1.230.231; 22.1.230.236; 22.1.230.237; 22.1.230.238; 22.1.230.239; 22.1.230.154; 22.1.230.157; 22.1.230.166; 22.1.230.169; 22.1.230.172; 22.1.230.175; 22.1.230.240; 22.1.230.244; 22.1.231.228; 22.1.231.229; 22.1.231.230; 22.1.231.231; 22.1.231.236; 22.1.231.237; 22.1.231.238; 22.1.231.239; 22.1.231.154; 22.1.231.157; 22.1.231.166; 22.1.231.169; 22.1.231.172; 22.1.231.175; 22.1.231.240; 22.1.231.244; 22.1.236.228; 22.1.236.229; 22.1.236.230; 22.1.236.231; 22.1.236.236; 22.1.236.237; 22.1.236.238; 22.1.236.239; 22.1.236.154; 22.1.236.157; 22.1.236.166; 22.1.236.169; 22.1.236.172; 22.1.236.175; 22.1.236.240; 22.1.236.244; 22.1.237.228; 22.1.237.229; 22.1.237.230; 22.1.237.231; 22.1.237.236; 22.1.237.237; 22.1.237.238; 22.1.237.239; 22.1.237.154; 22.1.237.157; 22.1.237.166; 22.1.237.169; 22.1.237.172; 22.1.237.175; 22.1.237.240; 22.1.237.244; 22.1.238.228; 22.1.238.229; 22.1.238.230; 22.1.238.231; 22.1.238.236; 22.1.238.237; 22.1.238.238; 22.1.238.239; 22.1.238.154; 22.1.238.157; 22.1.238.166; 22.1.238.169; 22.1.238.172; 22.1.238.175; 22.1.238.240; 22.1.238.244; 22.1.239.228; 22.1.239.229; 22.1.239.230; 22.1.239.231; 22.1.239.236; 22.1.239.237; 22.1.239.238; 22.1.239.239; 22.1.239.154; 22.1.239.157; 22.1.239.166; 22.1.239.169; 22.1.239.172; 22.1.239.175; 22.1.239.240; 22.1.239.244; 22.1.154.228; 22.1.154.229; 22.1.154.230; 22.1.154.231; 22.1.154.236; 22.1.154.237; 22.1.154.238; 22.1.154.239; 22.1.154.154; 22.1.154.157; 22.1.154.166; 22.1.154.169; 22.1.154.172; 22.1.154.175; 22.1.154.240; 22.1.154.244; 22.1.157.228; 22.1.157.229; 22.1.157.230; 22.1.157.231; 22.1.157.236; 22.1.157.237; 22.1.157.238; 22.1.157.239; 22.1.157.154; 22.1.157.157; 22.1.157.166; 22.1.157.169; 22.1.157.172; 22.1.157.175; 22.1.157.240; 22.1.157.244; 22.1.166.228; 22.1.166.229; 22.1.166.230; 22.1.166.231; 22.1.166.236; 22.1.166.237; 22.1.166.238; 22.1.166.239; 22.1.166.154; 22.1.166.157; 22.1.166.166; 22.1.166.169; 22.1.166.172; 22.1.166.175; 22.1.166.240; 22.1.166.244; 22.1.169.228; 22.1.169.229; 22.1.169.230; 22.1.169.231; 22.1.169.236; 22.1.169.237; 22.1.169.238; 22.1.169.239; 22.1.169.154; 22.1.169.157; 22.1.169.166; 22.1.169.169; 22.1.169.172; 22.1.169.175; 22.1.169.240; 22.1.169.244; 22.1.172.228; 22.1.172.229; 22.1.172.230; 22.1.172.231; 22.1.172.236; 22.1.172.237; 22.1.172.238; 22.1.172.239; 22.1.172.154; 22.1.172.157; 22.1.172.166; 22.1.172.169; 22.1.172.172; 22.1.172.175; 22.1.172.240; 22.1.172.244; 22.1.175.228; 22.1.175.229; 22.1.175.230; 22.1.175.231; 22.1.175.236; 22.1.175.237; 22.1.175.238; 22.1.175.239; 22.1.175.154; 22.1.175.157; 22.1.175.166; 22.1.175.169; 22.1.175.172; 22.1.175.175; 22.1.175.240; 22.1.175.244; 22.1.240.228; 22.1.240.229; 22.1.240.230; 22.1.240.231; 22.1.240.236; 22.1.240.237; 22.1.240.238; 22.1.240.239; 22.1.240.154; 22.1.240.157; 22.1.240.166; 22.1.240.169; 22.1.240.172; 22.1.240.175; 22.1.240.240; 22.1.240.244; 22.1.244.228; 22.1.244.229; 22.1.244.230; 22.1.244.231; 22.1.244.236; 22.1.244.237; 22.1.244.238; 22.1.244.239; 22.1.244.154; 22.1.244.157; 22.1.244.166; 22.1.244.169; 22.1.244.172; 22.1.244.175; 22.1.244.240; 22.1.244.244;

Prodrugs of22.T 22.J.228.228; 22.J.228.229; 22.J.228.230; 22.J.228.231; 22.J.228.236; 22.J.228.237; 22.J.228.238; 22J.228.239; 22J.228.154; 22J.228.157; 22.J.228.166; 22.J.228.169; 22J.228.172;22.J.228.175;22J.228.240;22J.228.244;22J.229.228;22.J.229.229; 22J.229.230; 22J.229.231; 22J.229.236; 22J.229.237; 22J.229.238; 22J.229.239; 22J.229.154; 22J.229.157; 22J.229.166; 22J.229.169; 22J.229.172; 22J.229.175; 22J.229.240; 22J.229.244; 22J.230.228; 22J.230.229; 22J.230.230; 22J.230.231; 22J.230.236; 22J.230.237; 22J.230.238; 22J.230.239; 22J.230.154; 22J.230.157; 22J.230.166; 22J.230.169; 22J.230.172; 22J.230.175; 22J.230.240; 22J.230.244; 22J.231.228; 22J.231.229; 22.J.231.230; 22J.231.231; 22J.231.236; 22J.231.237; 22J.231.238; 22J.231.239; 22J.231.154; 22J.231.157; 22J.231.166; 22J.231.169; 22J.231.172; 22J.231.175; 22J.231.240; 22J.231.244; 22J.236.228; 22J.236.229; 22J.236.230; 22J.236.231; 22J.236.236; 22J.236.237; 22J.236.238; 22J.236.239; 22J.236.154; 22J.236.157; 22J.236.166; 22J.236.169; 22J.236.172; 22.J.236.175; 22J.236.240; 22J.236.244; 22J.237.228; 22J.237.229; 22J.237.230; 22J.237.231; 22J.237.236; 22.J.237.237; 22J.237.238; 22J.237.239; 22J.237.154; 22J.237.157; 22J.237.166; 22J.237.169; 22J.237.172; 22J.237.175; 22.J.237.240; 22J.237.244; 22J.238.228; 22.J.238.229; 22J.238.230; 22J.238.231; 22.J.238.236; 22J.238.237; 22J.238.238; 22.J.238.239; 22J.238.154; 22J.238.157; 22J.238.166; 22J.238.169; 22J.238.172; 22J.238.175;22J.238.240; 22J.238.244;22J.239.228;22J.239.229; 22J.239.230; 22J.239.231; 22J.239.236; 22J.239.237; 22J.239.238; 22.J.239.239; 22J.239.154; 22J.239.157; 22.J.239.166; 22J.239.169; 22J.239.172; 22J.239.175; 22J.239.240; 22J.239.244; 22.J.154.228; 22J.154.229; 22J.154.230; 22.J.154.231; 22J.154.236; 22J.154.237; 22.J.154.238; 22J.154.239; 22J.154.154; 22J.154.157; 22.J.154.166; 22J.154.169; 22J.154.172; 22J.154.175; 22J.154.240; 22J.154.244; 22J.157.228; 22J.157.229; 22J.157.230; 22J.157.231; 22J.157.236; 22J.157.237; 22J.157.238; 22J.157.239; 22J.157.154; 22J.157.157; 22J.157.166; 22J.157.169; 22J.157.172; 22J.157.175; 22J.157.240; 22J.157.244; 22J.166.228; 22J.166.229; 22.J.166.230; 22J.166.231; 22J.166.236; 22J.166.237; 22J.166.238; 22J.166.239; 22.J.166.154; 22J.166.157; 22J.166.166; 22J.166.169; 22J.166.172; 22J.166.175; 22J.166.240; 22J.166.244; 22J.169.228; 22J.169.229; 22J.169.230; 22J.169.231; 22J.169.236; 22J.169.237; 22J.169.238; 22J.169.239; 22J.169.154; 22J.169.157; 22J.169.166; 22J.169.169; 22J.169.172; 22J.169.175; 22J.169.240; 22J.169.244; 22J.172.228; 22J.172.229; 22J.172.230; 22J.172.231; 22J.172.236; 22J.172.237; 22J.172.238; 22J.172.239; 22.J.172.154; 22J.172.157; 22J.172.166; 22J.172.169; 22J.172.172;22J.172.175; 22J.172.240; 22J.172.244;22J.175.228; 22J.175.229; 22.J.175.230; 22J.175.231; 22.J.175.236; 22J.175.237; 22J.175.238; 22J.175.239; 22.J.175.154; 22J.175.157; 22.J.175.166; 22J.175.169; 22J.175.172; 22J.175.175; 22.J.175.240; 22J.175.244; 22J.240.228; 22J.240.229; 22J.240.230; 22J.240.231; 22J.240.236; 22J.240.237; 22.J.240.238; 22J.240.239; 22J.24Q.154; 22J.240.157; 22J.240.166; 22J.240.169; 22.J.240.172; 22J.240.175; 22J.240.240; 22J.240.244; 22J.244.228; 22.J.244.229; 22.J.244.230; 22J.244.231; 22.J.244.236; 22J.244.237; 22J.244.238; 22J.244.239; 22J.244.154; 22J.244.157; 22J.244.166; 22J.244.169; 22J.244.172; 22.J.244.175; 22.J.244.240; 22J.244.244;

Prodrugs of22.L 22.L.228.228; 22.L.228.229; 22.L.228.230; 22.L.228.231; 22.L.228.236; 22.L.228.237; 22.L.228.238; 22.L.228.239; 22.L.228.154; 22.L.228.157; 22.L.228.166; 22.L.228.169; 22.L.228.172; 22.L.228.175; 22.L.228.24Q; 22.L.228.244; 22.L.229.228; 22.L.229.229; 22.L.229.230; 22.L.229.231; 22.L.229.236; 22.L.229.237; 22.L.229.238; 22.L.229.239; 22.L.229.154; 22.L.229.157; 22.L.229.166; 22.L.229.169; 22.L.229.172; 22.L.229.175; 22.L.229.240; 22.L.229.244; 22.L.230-228; 22.L.230.229; 22.L.230.230; 22.L.230.231; 22.L.230.236; 22.L.230.237; 22.L.230.238; 22.L.230-239; 22.L.230.154; 22.L.230.157; 22.L.230.166; 22.L.230-169; 22.L.230.172; 22.L.230.175; 22.L.230.240; 22.L.230.244; 22.L.231.228; 22.L.231.229; 22.L.231.230; 22.L.231.231; 22.L.231.236; 22.L.231.237; 22.L.231.238; 22.L.231.239; 22.L.231.154; 22.L.231.157; 22.L.231.166; 22.L.231.169; 22.L.231.172; 22.L.231.175; 22.L.231.240; 22.L.231.244; 22.L.236.228; 22.L.236.229; 22.L.236.230; 22.L.236.231; 22.L.236.236; 22.L.236.237; 22.L.236.238; 22.L.236.239; 22.L.236.154; 22.L.236.157; 22.L.236.166; 22.L.236.169; 22.L.236.172; 22.L.236.175; 22.L.236.240; 22.L.236.244; 22.L.237.228; 22.L.237.229; 22.L.237.230; 22.L.237.231; 22.L.237.236; 22.L.237.237; 22.L.237.238; 22.L.237.239; 22.L.237.154; 22.L.237.157; 22.L.237.166; 22.L.237.169; 22.L.237.172; 22.L.237.175; 22.L.237.240; 22.L.237.244; 22.L.238.228; 22.L.238.229; 22.L.238.230; 22.L.238.231; 22.L.238.236; 22.L.238.237; 22.L.238.238; 22.L.238.239; 22.L.238.154; 22.L.238.157; 22.L.238.166; 22.L.238.169; 22.L.238.172; 22.L.238.175; 22.L.238.240; 22.L.238.244; 22.L.239.228; 22.L.239.229; 22.L.239.230; 22.L.239.231; 22.L.239.236; 22.L.239.237; 22.L.239.238; 22.L.239.239; 22.L.239.154; 22.L.239.157; 22.L.239.166; 22.L.239.169; 22.L.239.172; 22.L.239.175; 22.L.239.240; 22.L.239.244; 22.L.154.228; 22.L.154.229; 22.L.154.230; 22.L.154.231; 22.L.154.236; 22.L.154.237; 22.L.154.238; 22.L.154.239; 22.L.154.154; 22.L.154.157; 22.L.154.166; 22.L.154.169; 22.L.154.172; 22.L.154.175; 22.L.154.240; 22.L.154.244; 22.L.157.228; 22.L.157.229; 22.L.157.230; 22.L.157.231; 22.L.157.236; 22.L.157.237; 22.L.157.238; 22.L.157.239; 22.L.157.154; 22.L.157.157; 22.L.157.166; 22.L.157.169; 22.L.157.172; 22.L.157.175; 22.L.157.240; 22.L.157.244; 22.L.166.228; 22.L.166.229; 22.L.166.230; 22.L.166.231; 22.L.166.236; 22.L.166.237; 22.L.166.238; 22.L.166.239; 22.L.166.154; 22.L.166.157; 22.L.166.166; 22.L.166.169; 22.L.166.172; 22.L.166.175; 22.L.166.240; 22.L.166.244; 22.L.169.228; 22.L.169.229; 22.L.169.230; 22.L.169.231; 22.L.169.236; 22.L.169.237; 22.L.169.238; 22.L.169.239; 22.L.169.154; 22.L.169.157; 22.L.169.166; 22.L.169.169; 22.L.169.172; 22.L.169.175; 22.L.169.240; 22.L.169.244; 22.L.172.228; 22.L.172.229; 22.L.172.230; 22.L.172.231; 22.L.172.236; 22.L.172.237; 22.L.172.238; 22.L.172.239; 22.L.172.154; 22.L.172.157; 22.L.172.166; 22.L.172.169; 22.L.172.172; 22.L.172.175; 22.L.172.240; 22.L.172.244; 22.L.175.228; 22.L.175.229; 22.L.175.230; 22.L.175.231; 22.L.175.236; 22.L.175.237; 22.L.175.238; 22.L.175.239; 22.L.175.154; 22.L.175.157; 22.L.175.166; 22.L.175.169; 22.L.175.172; 22.L.175.175; 22.L.175.240; 22.L.175.244; 22.L.240.228; 22.L.240.229; 22.L.240.230; 22.L.240.231; 22.L.240.236; 22.L.240.237; 22.L.240.238; 22.L.240.239; 22.L.240.154; 22.L.240.157; 22.L.240.166; 22.L.240.169; 22.L.240.172; 22.L.240.175; 22.L.240.240; 22.L.240.244; 22.L.244.228; 22.L.244.229; 22.L.244.230; 22.L.244.231; 22.L.244.236; 22.L.244.237; 22.L.244.238; 22.L.244.239; 22.L.244.154; 22.L.244.157; 22.L.244.166; 22.L.244.169; 22.L.244.172; 22.L.244.175; 22.L.244.240; 22.L.244.244;

Prodrugs of 22.O 22.O.228.228; 22.O.228.229; 22.O.228.230; 22.O.228.231; 22.O.228.236; 22.O.228.237; 22,.O.228.238; 22,,0.228.239; 22,.O.228.154; 22. O.228.157; 22.O.228.166; 22,.O.228.169; 22,O.228.172; 22,.O.228.175;22. .0.228.240; 22.O.228.244; 22,.O.229.228; 22,O.229.229; 22,.O.229.230; 22. O.229.231; 22.O.229.236; 22,.O.229.237; 22,O.229.238; 22,.O.229.239; 22. O.229.154; 22.O.229.157; 22,.O.229.166; 22,.O.229.169; 22,.O.229.172; 22. •O.229.175; 22.O.229.240; 22,,0.229.244; 22,,0.230.228; 22,•O.230.229;22. O.230.230; 22.O.230.231; 22,,0.230.236; 22,,0.230.237; 22,.O.230.238;22. .0.230.239; 22.O.230.154; 22,.0.230.157; 22,,0.230.166;22,.O.230.169; 22, O.230.172; 22.O.230.175; 22,.0.230.240; 22,,0.230.244; 22,.O.231.228; 22. O.231.229; 22.O.231.230; 22.O.231.231; 22.O.231.236;22.O.231.237;22, O.231.238; 22.0.231.239; 22.O.231.154; 22.O.231.157; 22.O.231.166;22, O.231.169; 22.0.231.172; 22..O.231.175; 22.0.231.240; 22.O.231.244; 22, .O.236.228; 22.O.236.229; 22,0.236.230; 22.O.236.231; 22.O.236.236; 22, .O.236.237; 22.O.236.238; 22.O.236.239; 22.O.236.154;22.O.236.157;22, O.236.166; 22.O.236.169; 22.O.236.172; 22.O.236.175; 22.O.236.240;22, .O.236.244; 22.O.237.228; 22.O.237.229; 22.O.237.230; 22.O.237.231;22, .O.237.236; 22.O.237.237; 22•O.237.238; 22.O.237.239; 22.O.237.154; 22, .O.237.157; 22.O.237.166; 22.O.237.169; 22.O.237.172; 22.O.237.175; 22, .0.237.240; 22.O.237.244; 22.O.238.228; 22.O.238.229; 22.O.238.230; 22, .O.238.231; 22.O.238.236; 22.O.238.237; 22.O.238.238; 22.O.238.239; 22, .O.238.154; 22.O.238.157; 22.O.238.166; 22.O.238.169; 22.O.238.172; 22, .O.238.175; 22.O.238.240; 22.O.238.244; 22.O.239.228; 22.0.239.229; 22, .0.239.230; 22.O.239.231; 22,0.239.236; 22.O.239.237; 22.O.239.238; 22, O.239.239; 22.O.239.154; 22.O.239.157; 22.O.239.166; 22.O.239.169; 22, .O.239.172; 22.O.239.175; 22,0.239.240; 22.O.239.244; 22.O.154.228; 22, O.154.229; 22.O.154.230; 22.O.154.231; 22.O.154.236; 22.O.154.237; 22, .O.154.238; 22.O.154.239; 22.O.154.154; 22.O.154.157; 22.O.154.166; 22, .O.154.169; 22.O.154.172; 22,.O.154.175; 22,,0.154.240; 22,.O.154.244; 22. .O.157.228; 22.O.157.229; 22,0.157.230; 22,.O.157.231; 22,.O.157.236; 22. .O.157.237; 22.O.157.238; 22,.O.157.239; 22,.O.157.154; 22,.O.157.157; 22. O.157.166; 22.O.157.169; 22,,0.157.172; 22,.O.157.175; 22,.O.157.240; 22. •O.157.244; 22.O.166.228; 22,O.166.229; 22,.0.166.230; 22,.O.166.231; 22. O.166.236; 22.O.166.237; 22,.O.166.238; 22,,0.166.239; 22,.O.166.154; 22. O.166.157; 22.O.166.166; 22,O.166.169; 22,.O.166.172; 22,•O.166.175; 22. .0.166.240; 22.O.166.244; 22,O.169.228; 22,.O.169.229;22,•O.169.230; 22. O.169.231; 22.O.169.236; 22,.O.169.237; 22,.O.169.238; 22,.O.169.239; 22. .O.169.154; 22.O.169.157; 22,O.169.166; 22,O.169.169; 22,.O.169.172;22. O.169.175; 22.O.169.240; 22..O.169.244; 22,O.172.228; 22,•O.172.229; 22. O.172.230; 22.O.172.231; 22..O.172.236; 22,O.172.237; 22,.O.172.238; 22. O.172.239; 22.O.172.154; 22,.O.172.157; 22.O.172.166; 22,•O.172.169; 22. O.172.172; 22.O.172.175; 22.O.172.240; 22.O.172.244; 22..O.175.228; 22. O.175.229; 22.O.175.230; 22.O.175.231; 22.O.175.236; 22..O.175.237; 22. O.175.238; 22.O.175.239; 22,.O.175.154; 22,O.175.157; 22,.O.175.166; 22, .O.175.169; 22.O.175.172; 22,.O.175.175; 22,.0.175.240; 22,•O.175.244; 22. .0.240.228; 22.O.240.229; 22,O.240.230; 22,.0.240.231; 22,.O.240.236; 22. O.240.237; 22.O.240.238; 22.O.240.239; 22.O.240.154; 22.O.240.157; 22.O.240.166; 22.O.240.169; 22.O.24Q.172; 22.O.240.175; 22.O.24Q.240; 22.O.240.244; 22.O.244.228; 22.O.244.229; 22.O.244.230; 22.O.244.231; 22.O.244.236; 22.O.244.237; 22.O.244.238; 22.O.244.239; 22.O.244.154; 22.O.244.157; 22.O.244.166; 22.O.244.169; 22.O.244.172; 22.O.244.175; 22.O.244.240; 22.O.244.244;

Prodrugs of 22.P

22.P.228.228; 22.P.228.229; 22.P.228.230; 22.P.228.231; 22.P.228.236; 22.P.228.237; 22.P.228.238; 22.P.228.239; 22.P.228.154; 22.P.228.157; 22.P.228.166; 22.P.228.169; 22.P.228.172; 22.P.228.175; 22.P.228.240; 22.P.228.244; 22.P.229.228; 22.P.229.229; 22.P.229.230; 22.P.229.231; 22.P.229.236; 22.P.229.237; 22.P.229.238; 22.P.229.239; 22.P.229.154; 22.P.229.157; 22.P.229.166; 22.P.229.169; 22.P.229.172; 22.P.229.175; 22.P.229.240; 22.P.229.244; 22.P.23Q.228; 22.P.230.229; 22.P.230.230; 22.P.230.231; 22.P.230.236; 22.P.230.237; 22.P.230.238; 22.P.230.239; 22.P.230.154; 22.P.23Q.157; 22.P.230.166; 22.P.23Q.169; 22.P.230.172; 22.P.230.175; 22.P.230.240; 22.P.230.244; 22.P.231.228; 22.P.231.229; 22.P.231.230; 22.P.231.231; 22.P.231.236; 22.P.231.237; 22.P.231.238; 22.P.231.239; 22.P.231.154; 22.P.231.157; 22.P.231.166; 22.P.231.169; 22.P.231.172; 22.P.231.175; 22.P.231.240; 22.P.231.244; 22.P.236.228; 22.P.236.229; 22.P.236.230; 22.P.236.231; 22.P.236.236; 22.P.236.237; 22.P.236.238; 22.P.236.239; 22.P.236.154; 22.P.236.157; 22.P.236.166; 22.P.236.169; 22.P.236.172; 22.P.236.175; 22.P.236.240; 22.P.236.244; 22.P.237.228; 22.P.237.229; 22.P.237.230; 22.P.237.231; 22.P.237.236; 22.P.237.237; 22.P.237.238; 22.P.237.239; 22.P.237.154; 22.P.237.157; 22.P.237.166; 22.P.237.169; 22.P.237.172; 22.P.237.175; 22.P.237.240; 22.P.237.244; 22.P.238.228; 22.P.238.229; 22.P.238.230; 22.P.238.231; 22.P.238.236; 22.P.238.237; 22.P.238.238; 22.P.238.239; 22.P.238.154; 22.P.238.157; 22.P.238.166; 22.P.238.169; 22.P.238.172; 22.P.238.175; 22.P.238.24Q; 22.P.238.244; 22.P.239.228; 22.P.239.229; 22.P.239.230; 22.P.239.231; 22.P.239.236; 22.P.239.237; 22.P.239.238; 22.P.239.239; 22.P.239.154; 22.P.239.157; 22.P.239.166; 22.P.239.169; 22.P.239.172; 22.P.239.175; 22.P.239.240; 22.P.239.244; 22.P.154.228; 22.P.154.229; 22.P.154.230; 22.P.154.231; 22.P.154.236; 22.P.154.237; 22.P.154.238; 22.P.154.239; 22.P.154.154; 22.P.154.157; 22.P.154.166; 22.P.154.169; 22.P.154.172; 22.P.154.175; 22.P.154.240; 22.P.154.244; 22.P.157.228; 22.P.157.229; 22.P.157.230; 22.P.157.231; 22.P.157.236; 22.P.157.237; 22.P.157.238; 22.P.157.239; 22.P.157.154; 22.P.157.157; 22.P.157.166; 22.P.157.169; 22.P.157.172; 22.P.157.175; 22.P.157.240; 22.P.157.244; 22.P.166.228; 22.P.166.229; 22.P.166.230; 22.P.166.231; 22.P.166.236; 22.P.166.237; 22.P.166.238; 22.P.166.239; 22.P.166.154; 22.P.166.157; 22.P.166.166; 22.P.166.169; 22.P.166.172; 22.P.166.175; 22.P.166.240; 22.P.166.244; 22.P.169.228; 22.P.169.229; 22.P.169.230; 22.P.169.231; 22.P.169.236; 22.P.169.237; 22.P.169.238; 22.P.169.239; 22.P.169.154; 22.P.169.157; 22.P.169.166; 22.P.169.169; 22.P.169.172; 22.P.169.175; 22.P.169.240; 22.P.169.244; 22.P.172.228; 22.P.172.229; 22.P.172.230; 22.P.172.231; 22.P.172.236; 22.P.172.237; 22.P.172.238; 22.P.172.239; 22.P.172.154; 22.P.172.157; 22.P.172.166; 22.P.172.169; 22.P.172.172; 22.P.172.175; 22.P.172.240; 22.P.172.244; 22.P.175.228; 22.P.175.229; 22.P.175.23Q; 22.P.175.231; 22.P.175.236; 22.P.175.237; 22.P.175.238; 22.P.175.239; 22.P.175.154; 22.P.175.157; 22.P.175.166; 22.P.175.169; 22.P.175.172; 22.P.175.175; 22.P.175.240; 22.P.175.244; 22.P.240.228; 22.P.240.229; 22.P.240.230; 22.P.240.231; 22.P.240.236; 22.P.240.237; 22.P.240.238; 22.P.240.239; 22.P.240.154; 22.P.240.157; 22.P.240.166; 22.P.240.169; 22.P.240.172; 22.P.240.175; 22.P.240.240; 22.P.240.244; 22.P.244.228; 22.P.244.229; 22.P.244.230; 22.P.244.231; 22.P.244.236; 22.P.244.237; 22.P.244.238; 22.P.244.239; 22.P.244.154; 22.P.244.157; 22.P.244.166; 22.P.244.169; 22.P.244.172; 22.P.244.175; 22.P.244.240; 22.P.244.244;

Prodrugs of 22.U

22.U.228.228; 22.U.228.229; 22.U.228.230; 22.U.228.231; 22.U.228.236; 22.U.228.237; 22.U.228.238; 22.U.228.239; 22.U.228.154; 22.U.228.157; 22.U.228.166; 22.U.228.169; 22.U.228.172; 22.U.228.175; 22.U.228.240; 22.U.228.244; 22.U.229.228; 22.U.229.229; 22.U.229.230; 22.U.229.231; 22.U.229.236; 22.U.229.237; 22.U.229.238; 22.U.229.239; 22.U.229.154; 22.U.229.157; 22.U.229.166; 22.U.229.169; 22.U.229.172; 22.U.229.175; 22.U.229.240; 22.U.229.244; 22.U.230.228; 22.U.230.229; 22.U.230.230; 22.U.230.231; 22.U.230.236; 22.U.230.237; 22.U.230.238; 22.U.230.239; 22.U.230.154; 22.U.230.157; 22.U.230.166; 22.U.230.169; 22.U.230.172; 22.U.230.175; 22.U.230.240; 22.U.230.244; 22.U.231.228; 22.U.231.229; 22.U.231.230; 22.U.231.231; 22.U.231.236; 22.U.231.237; 22.U.231.238; 22.U.231.239; 22.U.231.154; 22.U.231.157; 22.U.231.166; 22.U.231.169; 22.U.231.172; 22.U.231.175; 22.U.231.240; 22.U.231.244; 22.U.236.228; 22.U.236.229; 22.U.236.230; 22.U.236.231; 22.U.236.236; 22.U.236.237; 22.U.236.238; 22.U.236.239; 22.U.236.154; 22.U.236.157; 22.U.236.166; 22.U.236.169; 22.U.236.172; 22.U.236.175; 22.U.236.240; 22.U.236.244; 22.U.237.228; 22.U.237.229; 22.U.237.230; 22.U.237.231; 22.U.237.236; 22.U.237.237; 22.U.237.238; 22.U.237.239; 22.U.237.154; 22.U.237.157; 22.U.237.166; 22.U.237.169; 22.U.237.172; 22.U.237.175; 22.U.237.240; 22.U.237.244; 22.U.238.228; 22.U.238.229; 22.U.238.230; 22.U.238.231; 22.U.238.236; 22.U.238.237; 22.U.238.238; 22.U.238.239; 22.U.238.154; 22.U.238.157; 22.U.238.166; 22.U.238.169; 22.U.238.172; 22.U.238.175; 22.U.238.240; 22.U.238.244; 22.U.239.228; 22.U.239.229; 22.U.239.230; 22.U.239.231; 22.U.239.236; 22.U.239.237; 22.U.239.238; 22.U.239.239; 22.U.239.154; 22.U.239.157; 22.U.239.166; 22.U.239.169; 22.U.239.172; 22.U.239.175; 22.U.239.240; 22.U.239.244; 22.U.154.228; 22.U.154.229; 22.U.154.230; 22.U.154.231; 22.U.154.236; 22.U.154.237; 22.U.154.238; 22.U.154.239; 22.U.154.154; 22.U.154.157; 22.U.154.166; 22.U.154.169; 22.U.154.172; 22.U.154.175; 22.U.154.240; 22.U.154.244; 22.U.157.228; 22.U.157.229; 22.U.157.230; 22.U.157.231; 22.U.157.236; 22.U.157.237; 22.U.157.238; 22.U.157.239; 22.U.157.154; 22.U.157.157; 22.U.157.166; 22.U.157.169; 22.U.157.172; 22.U.157.175; 22.U.157.240; 22.U.157.244; 22.U.166.228; 22.U.166.229; 22.U.166.230; 22.U.166.231; 22.U.166.236; 22.U.166.237; 22.U.166.238; 22.U.166.239; 22.U.166.154; 22.U.166.157; 22.U.166.166; 22.U.166.169; 22.U.166.172; 22.U.166.175; 22.U.166.240; 22.U.166.244; 22.U.169.228; 22.U.169.229; 22.U.169.230; 22.U.169.231; 22.U.169.236; 22.U.169.237; 22.U.169.238; 22.U.169.239; 22.U.169.154; 22.U.169.157; 22. U.169.166; 22.U.169.169; 22.U.169.172; 22.U.169.175; 22.U.169.240; 22.U.169.244; 22.U.172.228; 22.U.172.229; 22.U.172.230; 22.U.172.231; 22.U.172.236; 22.U.172.237; 22.U.172.238; 22.U.172.239; 22.U.172.154; 22.U.172.157; 22.U.172.166; 22.U.172.169; 22.U.172.172; 22.U.172.175; 22.U.172.240; 22.U.172.244; 22.U.175.228; 22.U.175.229; 22.U.175.23Q; 22.U.175.231; 22.U.175.236; 22.U.175.237; 22.U.175.238; 22.U.175.239; 22.U.175.154; 22.U.175.157; 22.U.175.166; 22.U.175.169; 22.U.175.172; 22.U.175.175; 22.U.175.240; 22.U.175.244; 22.U.240.228; 22.U.240.229; 22.U.240.230; 22.U.240.231; 22.U.240.236; 22.U.240.237; 22.U.240.238; 22.U.240.239; 22.U.240.154; 22.U.240.157; 22.U.240.166; 22.U.240.169; 22.U.240.172; 22.U.240.175; 22.U.240.240; 22.U.240.244; 22.U.244.228; 22.U.244.229; 22.U.244.230; 22.U.244.231; 22.U.244.236; 22.U.244.237; 22.U.244.238; 22.U.244.239; 22.U.244.154; 22.U.244.157; 22.U.244.166; 22.U.244.169; 22.U.244.172; 22.U.244.175; 22.U.244.240; 22.U.244.244;

Prodrugs of 22.CD

22.CD.228.228; 22.CD.228.229; 22.CD.228.230; 22.CD.228.231; 22.CD.228.236; 22.CD.228.237; 22.CD.228.238; 22.CD.228.239; 22.CD.228.154; 22.CD.228.157; 22.CD.228.166; 22.CD.228.169; 22.CD.228.172; 22.CD.228.175; 22.CD.228.240; 22.CD.228.244; 22.CD.229.228; 22.CD.229.229; 22.CD.229.230; 22.CD.229.231; 22.CD.229.236; 22.CD.229.237; 22.CD.229.238; 22.CD.229.239; 22.CD.229.154; 22.CD.229.157; 22.CD.229.166; 22.CU229.169; 22.CD.229.172; 22.CD.229.175; 22.CD.229.240; 22.CD.229.244; 22.CD.230.228; 22.CD.230.229; 22.CD.230.230; 22.CD.230.231; 22.CD.230.236; 22.CD.230.237; 22.CD.230.238; 22.CD.230.239; 22.CD.230.154; 22.CD.230.157; 22.CD.230.166; 22.CD.230.169; 22.CD.230.172; 22.CD.230.175; 22.CD.230.240; 22.CD.230.244; 22.CD.231.228; 22.CD.231.229; 22.CD.231.230; 22.CD.231.231; 22.CD.231.236; 22.CD.231.237; 22.CD.231.238; 22.CD.231.239; 22.CD.231.154; 22.CD.231.157; 22.CD.231.166; 22.CD.231.169; 22.CD.231.172; 22.CD.231.175; 22.CD.231.240; 22.CD.231.244; 22.CD.236.228; 22.CD.236.229; 22.CD.236.230; 22.CD.236.231; 22.CD.236.236; 22.CD.236.237; 22.CD.236.238; 22.CD.236.239; 22.CD.236.154; 22.CD.236.157; 22.CD.236.166; 22.CD.236.169; 22.CD.236.172; 22.CD.236.175; 22.CD.236.240; 22.CD.236.244; 22.CD.237.228; 22.CD.237.229; 22.CD.237.230; 22.CD.237.231; 22.CD.237.236; 22.CD.237.237; 22.CD.237.238; 22.CD.237.239; 22.CD.237.154; 22.CD.237.157; 22.CD.237.166; 22.CD.237.169; 22.CD.237.172; 22.CD.237.175; 22.CD.237.240; 22.CD.237.244; 22.CD.238.228; 22.CD.238.229; 22.CD.238.230; 22.CD.238.231; 22.CD.238.236; 22.CD.238.237; 22.CD.238.238; 22.CD.238.239; 22.CD.238.154; 22.CD.238.157; 22.CD.238.166; 22.CD.238.169; 22.CD.238.172; 22.CD.238.175; 22.CD.238.240; 22.CD.238.244; 22.CD.239.228; 22.CD.239.229; 22.CD.239.230; 22.CD.239.231; 22.CD.239.236; 22.CD.239.237; 22.CD.239.238; 22.CD.239.239; 22.CD.239.154; 22.CD.239.157; 22.CD.239.166; 22.CD.239.169; 22.CD.239.172; 22.CD.239.175; 22.CD.239.240; 22.CD.239.244; 22.CD.154.228; 22.CD.154.229; 22.CD.154.230; 22.CD.154.231; 22.CD.154.236; 22.CD.154.237; 22.CD.154.238; 22.CD.154.239; 22.CD.154.154; 22.CD.154.157; 22.CD.154.166; 22.CD.154.169; 22.CD.154.172; 22.CD.154.175; 22.CD.154.240; 22.CD.154.244; 22.CD.157.228; 22.CD.157.229; 22.CD.157.230; 22.CD.157.231; 22.CD.157.236; 22.CD.157.237; 22.CD.157.238; 22.CD.157.239; 22.CD.157.154; 22.CD.157.157; 22.CD.157.166; 22.CD.157.169; 22.CD.157.172; 22.CD.157.175; 22.CD.157.240; 22.CD.157.244; 22.CD.166.228; 22.CD.166.229; 22.CD.166.230; 22.CD.166.231; 22.CD.166.236; 22.CD.166.237; 22.CD.166.238; 22.CD.166.239; 22.CD.166.154; 22.CD.166.157; 22.CD.166.166; 22.CD.166.169; 22.CD.166.172; 22.CD.166.175; 22.CD.166.240; 22.CD.166.244; 22.CD.169.228; 22.CD.169.229; 22.CD.169.230; 22.CD.169.231; 22.CD.169.236; 22.CD.169.237; 22.CD.169.238; 22.CD.169.239; 22.CD.169.154; 22.CD.169.157; 22.CD.169.166; 22.CD.169.169; 22.CD.169.172; 22.CD.169.175; 22.CD.169.240; 22.CD.169.244; 22.CD.172.228; 22.CD.172.229; 22.CD.172.230; 22.CD.172.231; 22.CD.172.236; 22.CD.172.237; 22.CD.172.238; 22.CD.172.239; 22.CD.172.154; 22.CD.172.157; 22.C.D.172.166; 22.CD.172.169; 22.CD.172.172; 22.CD.172.175; 22.CD.172.240; 22.CD.172.244; 22.CD.175.228; 22.CD.175.229; 22.CD.175.230; 22.CD.175.231; 22.CD.175.236; 22.CD.175.237; 22.CD.175.238; 22.CD.175.239; 22.CD.175.154; 22.CD.175.157; 22.CD.175.166; 22.CD.175.169; 22.CD.175.172; 22.CD.175.175; 22.CD.175.240; 22.CD.175.244; 22.CD.240.228; 22.CD.240.229; 22.CD.240.230; 22.CD.240.231; 22.CD.240.236; 22.CD.240.237; 22.CD.240.238; 22.CD.240.239; 22.CD.240.154; 22.CD.240.157; 22.CD.240.166; 22.CD.240.169; 22.CD.240.172; 22.CD.240.175; 22.CD.240.240; 22.CD.240.244; 22.CD.244.228; 22.CD.244.229; 22.CD.244.230; 22.CD.244.231; 22.CD.244.236; 22.CD.244.237; 22.CD.244.238; 22.CD.244.239; 22.CD.244.154; 22.CD.244.157; 22.CD.244.166; 22.CD.244.169; 22.CD.244.172; 22.CD.244.175; 22.CD.244.240; 22.CD.244.244;

Prodrugs of 22.EB

22.EB.228.228; 22.EB.228.229; 22.EB.228.230; 22.EB.228.231; 22.EB.228.236; 22.EB.228.237; 22.EB.228.238; 22.EB.228.239; 22.EB.228.154; 22.EB.228.157; 22.EB.228.166; 22.EB.228.169; 22.EB.228.172; 22.EB.228.175; 22.EB.228.240; 22.EB.228.244; 22.EB.229.228; 22.EB.229.229; 22.EB.229.230; 22.EB.229.231; 22.EB.229.236; 22.EB.229.237; 22.EB.229.238; 22.EB.229.239; 22.EB.229.154; 22.EB.229.157; 22.EB.229.166; 22.EB.229.169; 22.EB.229.172; 22.EB.229.175; 22.EB.229.240; 22.EB.229.244; 22.EB.230.228; 22.EB.230.229; 22.EB.230.230; 22.EB.230.231; 22.EB.230.236; 22.EB.230.237; 22.EB.230.238; 22.EB.230.239; 22.EB.230.154; 22.EB.230.157; 22.EB.23Q.166; 22.EB.230.169; 22.EB.230.172; 22.EB.230.175; 22.EB.230.240; 22.EB.230.244; 22.EB.231.228; 22.EB.231.229; 22.EB.231.230; 22.EB.231.231; 22.EB.231.236; 22.EB.231.237; 22.EB.231.238; 22.EB.231.239; 22.EB.231.154; 22.EB.231.157; 22.EB.231.166; 22.EB.231.169; 22.EB.231.172; 22.EB.231.175; 22.EB.231.240; 22.EB .231.244; 22.EB.236.228; 22.EB.236.229; 22.EB.236.230; 22.EB.236.231; 22.EB.236.236; 22.EB.236.237; 22.EB.236.238; 22.EB.236.239; 22.EB.236.154; 22.EB.236.157; 22.EB.236.166; 22.EB.236.169; 22.EB.236.172; 22.EB.236.175; 22.EB.236.240; 22.EB.236.244; 22.EB.237.228; 22.EB.237.229; 22.EB.237.230; 22.EB.237.231; 22.EB.237.236; 22.EB.237.237; 22.EB.237.238; 22.EB.237.239; 22.EB.237.154; 22.EB.237.157; 22.EB.237.166; 22.EB.237.169; 22.EB.237.172; 22.EB.237.175; 22.EB.237.240; 22.EB.237.244; 22.EB.238.228; 22.EB.238.229; 22.EB.238.230; 22.EB.238.231; 22.EB.238.236; 22.EB.238.237; 22.EB.238.238; 22.EB.238.239; 22.EB.238.154; 22.EB.238.157; 22.EB.238.166; 22.EB.238.169; 22.EB.238.172; 22.EB.238.175; 22.EB.238.240; 22.EB.238.244; 22.EB.239.228; 22.EB .239.229; 22.EB.239.230; 22.EB.239.231; 22.EB.239.236; 22.EB.239.237; 22.EB.239.238; 22.EB.239.239; 22.EB.239.154; 22.EB.239.157; 22.EB.239.166; 22.EB.239.169; 22.EB.239.172; 22.EB.239.175; 22.EB.239.240; 22.EB.239.244; 22.EB.154.228; 22.EB.154.229; 22.EB.154.230; 22.EB.154.231; 22.EB.154.236; 22.EB.154.237; 22.EB.154.238; 22.EB.154.239; 22.EB.154.154; 22.EB.154.157; 22.EB.154.166; 22.EB.154.169; 22.EB.154.172; 22.EB.154.175; 22.EB.154.240; 22.EB.154.244; 22.EB.157.228; 22.EB.157.229; 22.EB.157.230; 22.EB.157.231; 22.EB.157.236; 22.EB.157.237; 22.EB.157.238; 22.EB.157.239; 22.EB.157.154; 22.EB.157.157; 22.EB.157.166; 22.EB.157.169; 22.EB.157.172; 22.EB.157.175; 22.EB.157.240; 22.EB.157.244; 22.EB.166.228; 22.EB.166.229; 22.EB.166.230; 22.EB.166.231; 22.EB.166.236; 22.EB.166.237; 22.EB.166.238; 22.EB.166.239; 22.EB.166.154; 22.EB.166.157; 22.EB.166.166; 22.EB.166.169; 22.EB.166.172; 22.EB.166.175; 22.EB.166.240; 22.EB.166.244; 22.EB.169.228; 22.EB.169.229; 22.EB.169.230; 22.EB.169.231; 22.EB.169.236; 22.EB.169.237; 22.EB.169.238; 22.EB.169.239; 22.EB.169.154; 22.EB.169.157; 22.EB.169.166; 22.EB.169.169; 22.EB.169.172; 22.EB.169.175; 22.EB.169.240; 22.EB.169.244; 22.EB.172.228; 22.EB.172.229; 22.EB.172.230; 22.EB.172.231; 22.EB.172.236; 22.EB.172.237; 22.EB.172.238; 22.EB.172.239; 22.EB.172.154; 22.EB.172.157; 22.EB.172.166; 22.EB.172.169; 22.EB.172.172; 22.EB.172.175; 22.EB.172.240; 22.EB.172.244; 22.EB.175.228; 22.EB.175.229; 22.EB.175.230; 22.EB.175.231; 22.EB.175.236; 22.EB.175.237; 22.EB.175.238; 22.EB.175.239; 22.EB.175.154; 22.EB.175.157; 22.EB.175.166; 22.EB.175.169; 22.EB.175.172; 22.EB.175.175; 22.EB.175.240; 22.EB.175.244; 22.EB.240.228; 22.EB.240.229; 22.EB.240.230; 22.EB.240.231; 22.EB.240.236; 22.EB.240.237; 22.EB.240.238; 22.EB.240.239; 22.EB .240.154; 22.EB.240.157; 22.EB.240.166; 22.EB.240.169; 22.EB.240.172; 22.EB.240.175; 22.EB.240.240; 22.EB.240.244; 22.EB.244.228; 22.EB.244.229; 22.EB.244.230; 22.EB.244.231; 22.EB.244.236; 22.EB.244.237; 22.EB.244.238; 22.EB.244.239; 22.EB.244.154; 22.EB.244.157; 22.EB.244.166; 22.EB.244.169; 22.EB.244.172; 22.EB.244.175; 22.EB.244.240; 22.EB.244.244.

Prodrugs of 23.B

23.B.228.228; 23.B.228.229; 23.B.228.230; 23.B.228.231; 23.B.228.236; 23.B.228.237; 23.B.228.238; 23.B.228.239; 23.B.228.154; 23.B.228.157; 23.B.228.166; 23.B.228.169; 23.B.228.172; 23.B.228.175; 23.B.228.240; 23.B.228.244; 23.B.229.228; 23.B.229.229; 23.B.229.230; 23.B.229.231; 23.B.229.236; 23.B.229.237; 23.B.229.238; 23.B.229.239; 23.B.229.154; 23.B.229.157; 23.B.229.166; 23.B.229.169; 23.B.229.172; 23.B.229.175; 23.B.229.240; 23.B.229.244; 23.B.230.228; 23.B.230.229; 23.B.230.230; 23.B.230.231; 23.B.230.236; 23.B.230.237; 23.B.230.238; 23.B.230.239; 23.B.230.154; 23.B.230.157; 23.B.230.166; 23.B.230.169; 23.B.230.172; 23.B.230.175; 23.B.230.240; 23.B.230.244; 23.B.231.228; 23.B.231.229; 23.B.231.230; 23.B.231.231; 23.B.231.236; 23.B.231.237; 23.B.231.238; 23.B.231.239; 23.B.231.154; 23.B.231.157; 23.B.231.166; 23.B.231.169; 23.B.231.172; 23.B.231.175; 23.B.231.240; 23.B.231.244; 23.B.236.228; 23.B.236.229; 23.B.236.230; 23.B.236.231; 23.B.236.236; 23.B.236.237; 23.B.236.238; 23.B.236.239; 23.B.236.154; 23.B.236.157; 23.B.236.166; 23.B.236.169; 23.B.236.172; 23.B.236.175; 23.B.236.240; 23.B.236.244; 23.B.237.228; 23.B.237.229; 23.B.237.230; 23.B.237.231; 23.B.237.236; 23.B.237.237; 23.B.237.238; 23.B.237.239; 23.B.237.154; 23.B.237.157; 23.B.237.166; 23.B.237.169; 23.B.237.172; 23.B.237.175; 23.B.237.240; 23.B.237.244; 23.B.238.228; 23.B.238.229; 23.B.238.230; 23.B.238.231; 23.B.238.236; 23.B.238.237; 23.B.238.238; 23.B.238.239; 23.B.238.154; 23.B.238.157; 23.B.238.166; 23.B.238.169; 23.B.238.172; 23.B.238.175; 23.B.238.240; 23.B.238.244; 23.B.239.228; 23.B.239.229; 23.B.239.230; 23.B.239.231; 23.B.239.236; 23.B.239.237; 23.B.239.238; 23.B.239.239; 23.B.239.154; 23.B.239.157; 23.B.239.166; 23.B.239.169; 23.B.239.172; 23.B.239.175; 23.B.239.240; 23.B.239.244; 23.B.154.228; 23.B.154.229; 23.B.154.230; 23.B.154.231; 23.B.154.236; 23.B.154.237; 23.B.154.238; 23.B.154.239; 23.B.154.154; 23.B.154.157; 23.B.154.166; 23.B.154.169; 23.B.154.172; 23.B.154.175; 23.B.154.240; 23.B.154.244; 23.B.157.228; 23.B.157.229; 23.B.157.230; 23.B.157.231; 23.B.157.236; 23.B.157.237; 23.B.157.238; 23.B.157.239; 23.B.157.154; 23.B.157.157; 23.B.157.166; 23.B.157.169; 23.B.157.172; 23.B.157.175; 23.B.157.24Q; 23.B.157.244; 23.B.166.228; 23.B.166.229; 23.B.166.230; 23.B.166.231; 23.B.166.236; 23.B.166.237; 23.B.166.238; 23.B.166.239; 23.B.166.154; 23.B.166.157; 23.B.166.166; 23.B.166.169; 23.B.166.172; 23.B.166.175; 23.B.166.240; 23.B.166.244; 23.B.169.228; 23.B.169.229; 23.B.169.230; 23.B.169.231; 23.B.169.236; 23.B.169.237; 23.B.169.238; 23.B.169.239; 23.B.169.154; 23.B.169.157; 23.B.169.166; 23.B.169.169; 23.B.169.172; 23.B.169.175; 23.B.169.240; 23.B.169.244; 23.B.172.228; 23.B.172.229; 23.B.172.230; 23.B.172.231; 23.B.172.236; 23.B.172.237; 23-B.172.238; 23.B.172.239; 23.B.172.154; 23.B.172.157; 23.B.172.166; 23.B.172.169; 23.B.172.172; 23.B.172.175; 23.B.172.240; 23.B.172.244; 23.B.175.228; 23.B.175.229; 23.B.175.230; 23.B.175.231; 23.B.175.236; 23.B.175.237; 23.B.175.238; 23.B.175.239; 23.B.175.154; 23.B.175.157; 23.B.175.166; 23.B.175.169; 23.B.175.172; 23.B.175.175; 23.B.175.240; 23.B.175.244; 23.B.240.228; 23.B.240.229; 23.B.24Q.230; 23.B.240.231; 23.B.240.236; 23.B.240-237; 23.B.240.238; 23.B.240.239; 23.B.240.154; 23.B.240.157; 23.B.240.166; 23.B.240.169; 23.B.240.172; 23.B.240.175; 23.B.240.240; 23.B.240.244; 23.B.244.228; 23.B.244.229; 23.B.244.230; 23.B.244.231; 23.B.244.236; 23.B.244.237; 23.B.244.238; 23.B.244.239; 23.B.244.154; 23.B.244.157; 23.B.244.166; 23.B.244.169; 23.B.244.172; 23.B.244.175; 23.B.244.240; 23.B.244.244;

Prodrugs of 23.D

23.D.228.228; 23.D.228.229; 23.D.228.230; 23.D.228.231; 23.D.228.236; 23.D.228.237; 23.D.228.238; 23.D.228.239; 23.D.228.154; 23.D.228.157; 23.D.228.166; 23.D.228.169; 23.D.228.172; 23.D.228.175; 23.D.228.240; 23.D.228.244; 23.D.229.228; 23.D.229.229; 23.D.229.230; 23.D.229.231; 23.D.229.236; 23.D.229.237; 23.D.229.238; 23.D.229.239; 23.D.229.154; 23.D.229.157; 23.D.229.166; 23.D.229.169; 23.D.229.172; 23.D.229.175; 23.D.229.240; 23.D.229.244; 23.D.230.228; 23.D.230.229; 23.D.230.230; 23.D.230.231; 23.D.230.236; 23.D.23Q.237; 23.D.230.238; 23.D.230.239; 23.D.230.154; 23.D.230.157; 23.D.230.166; 23.D.230.169; 23.D.230.172; 23.D.230.175; 23.D.230.240; 23.D.230.244; 23.D.231.228; 23.D.231.229; 23.D.231.230; 23.D.231.231; 23.D.231.236; 23.D.231.237; 23.D.231.238; 23.D.231.239; 23.D.231.154; 23.D.231.157; 23.D.231.166; 23.D.231.169; 23.D.231.172; 23.D.231.175; 23.D.231.240; 23.D.231.244; 23.D.236.228; 23.D.236.229; 23.D.236.230; 23.D.236.231; 23.D.236.236; 23.D.236.237; 23.D.236.238; 23.D.236.239; 23.D.236.154; 23.D.236.157; 23.D.236.166; 23.D.236.169; 23.D.236.172; 23.P.236.175; 23.D.236.240; 23.D.236.244; 23.D.237.228; 23.D.237.229; 23.D.237.230; 23.D.237.231; 23.D.237.236; 23.D.237.237; 23.D.237.238; 23.D.237.239; 23.D.237.154; 23.D.237.157; 23.D.237.166; 23.D.237.169; 23.D.237.172; 23.D.237.175; 23.D.237.240; 23.D.237.244; 23.D.238.228; 23.D.238.229; 23.D.238.230; 23.D.238.231; 23.D.238.236; 23.D.238.237; 23.D.238.238; 23.D.238.239; 23.D.238.154; 23.D.238.157; 23.D.238.166; 23.D.238.169; 23.D.238.172; 23.D.238.175; 23.D.238.240; 23.D.238.244; 23.D.239.228; 23.D.239.229; 23.D.239.230; 23.D.239.231; 23.D.239.236; 23.D.239.237; 23.D.239.238; 23.D.239.239; 23.D.239.154; 23.D.239.157; 23.D.239.166; 23.D.239.169; 23.D.239.172; 23.D.239.175; 23.D.239.240; 23.D.239.244; 23.D.154.228; 23.D.154.229; 23.D.154.230; 23.D.154.231; 23.D.154.236; 23.D.154.237; 23.D.154.238; 23.D.154.239; 23.D.154.154; 23.D.154.157; 23.D.154.166; 23.D.154.169; 23.D.154.172; 23.D.154.175; 23.D.154.240; 23.D.154.244; 23.D.157.228; 23.D.157.229; 23.D.157.230; 23.D.157.231; 23.D.157.236; 23.D.157.237; 23.D.157.238; 23.D.157.239; 23.D.157.154; 23.D.157.157; 23.D.157.166; 23.D.157.169; 23.D.157.172; 23.D.157.175; 23.D.157.240; 23.D.157.244; 23.D.166.228; 23.D.166.229; 23.D.166.230; 23.D.166.231; 23.D.166.236; 23.D.166.237; 23.D.166.238; 23.D.166.239; 23.D.166.154; 23.D.166.157; 23.D.166.166; 23.D.166.169; 23.D.166.172; 23.D.166.175; 23.D.166.240; 23.D.166.244; 23.D.169.228; 23.D.169.229; 23.D.169.230; 23.D.169.231; 23.D.169.236; 23.D.169.237; 23.D.169.238; 23.D.169.239; 23.D.169.154; 23.O.169.157; 23.D.169.166; 23.D.169.169; 23.D.169.172; 23.D.169.175; 23.D.169.240; 23.D.169.244; 23.D.172.228; 23.D.172.229; 23.D.172.230; 23.D.172.231; 23.D.172.236; 23.D.172.237; 23.D.172.238; 23.D.172.239; 23.D.172.154; 23.D.172.157; 23.D.172.166; 23.D.172.169; 23.D.172.172; 23.D.172.175; 23.D.172.240; 23.D.172.244; 23.D.175.228; 23.D.175.229; 23.D.175.230; 23.D.175.231; 23.D.175.236; 23.D.175.237; 23.D.175.238; 23.D.175.239; 23.D.175.154; 23.D.175.157; 23.D.175.166; 23.D.175.169; 23.D.175.172; 23.D.175.175; 23.D.175.240; 23.D.175.244; 23.D.240.228; 23.D.240.229; 23.D.240.230; 23.D.240.231; 23.D.240.236; 23.D.240.237; 23.D.240.238; 23.D.240.239; 23.D.240.154; 23.D.240.157; 23.D.240.166; 23.D.240.169; 23.D.240.172; 23.D.240.175; 23.D.240.240; 23.D.240.244; 23.D.244.228; 23.D.244.229; 23.D.244.230; 23.D.244.231; 23.D.244.236; 23.D.244.237; 23.D.244.238; 23.D.244.239; 23.D.244.154; 23.D.244.157; 23.D.244.166; 23.D.244.169; 23.D.244.172; 23.D.244.175; 23.D.244.240; 23.D.244.244;

Prodrugs of 23.AB

23.AB.228.228; 23.AB.228.229; 23.AB.228.230; 23.AB.228.231; 23.AB.228.236; 23.AB.228.237; 23.AB.228.238; 23.AB.228.239; 23.AB.228.154; 23.AB.228.157; 23.AB.228.166; 23.AB.228.169; 23.AB.228.172; 23. AB.228.175; 23.AB.228.240; 23.AB.228.244; 23.AB.229.228; 23.AB.229.229; 23.AB.229.230; 23.AB.229.231; 23.AB.229.236; 23.AB.229.237; 23.AB.229.238; 23.AB.229.239; 23.AB.229.154; 23.AB.229.157; 23.AB.229.166; 23.AB.229.169; 23. AB.229.172; 23.AB.229.175; 23.AB.229.240; 23.AB.229.244; 23.AB.230.228; 23.AB.230.229; 23.AB.230.230; 23.AB.230.231; 23.AB.230.236; 23.AB.230.237; 23.AB.230.238; 23.AB.230.239; 23.AB.230.154; 23.AB.230.157; 23.AB.230.166; 23.AB.230.169; 23.AB.230.172; 23.AB.230.175; 23.AB.230.240; 23.AB.230.244; 23.AB.231.228; 23.AB.231.229; 23.AB.231.230; 23.AB.231.231; 23.AB.231.236; 23.AB.231.237; 23.AB.231.238; 23.AB.231.239; 23.AB.231.154; 23.AB.231.157; 23. AB.231.166; 23.AB.231.169; 23.AB.231.172; 23.AB.231.175; 23.AB.231.240; 23.AB.231.244; 23.AB.236.228; 23.AB.236.229; 23.AB.236.230; 23.AB.236.231; 23.AB.236.236; 23.AB.236.237; 23.AB.236.238; 23.AB.236.239; 23.AB.236.154; 23.AB.236.157; 23.AB.236.166; 23.AB.236.169; 23.AB.236.172; 23.AB.236.175; 23.AB.236.240; 23. AB.236.244; 23.AB.237.228; 23.AB .237.229; 23.AB.237.230; 23.AB.237.231; 23.AB.237.236; 23.AB.237.237; 23.AB.237.238; 23.AB.237.239; 23.AB.237.154; 23.AB.237.157; 23.AB.237.166; 23.AB.237.169; 23.AB.237.172; 23.AB.237.175; 23.AB.237.240; 23.AB.237.244; 23.AB.238.228; 23.AB.238.229; 23.AB.238.230; 23.AB.238.231; 23.AB.238.236; 23.AB.238.237; 23.AB.238.238; 23.AB.238.239; 23.AB.238.154; 23.AB.238.157; 23.AB.238.166; 23.AB.238.169; 23. AB.238.172; 23.AB.238.175; 23.AB.238.240; 23.AB.238.244; 23.AB.239.228; 23.AB.239.229; 23. AB.239.230; 23.AB.239.231; 23.AB.239.236; 23.AB.239.237; 23.AB.239.238; 23.AB.239.239; 23.AB.239.154; 23.AB.239.157; 23.AB.239.166; 23. AB.239.169; 23.AB.239.172; 23.AB.239.175; 23.AB.239.240; 23.AB.239.244; 23.AB.154.228; 23.AB.154.229; 23.AB.154.230; 23.AB.154.231; 23.AB.154.236; 23.AB.154.237; 23.AB.154.238; 23.AB.154.239; 23.AB.154.154; 23.AB.154.157; 23.AB.154.166; 23.AB.154.169; 23.AB.154.172; 23.AB.154.175; 23.AB.154.240; 23.AB.154.244; 23.AB.157.228; 23.AB.157.229; 23.AB.157.230; 23.AB.157.231; 23.AB.157.236; 23.AB.157.237; 23.AB.157.238; 23.AB.157.239; 23.AB.157.154; 23.AB.157.157; 23.AB.157.166; 23.AB.157.169; 23.AB.157.172; 23.AB.157.175; 23.AB.157.240; 23.AB.157.244; 23.AB.166.228; 23.AB.166.229; 23.AB.166.230; 23.AB.166.231; 23.AB.166.236; 23.AB.166.237; 23.AB.166.238; 23.AB.166.239; 23.AB.166.154; 23.AB.166.157; 23.AB.166.166; 23.AB.166.169; 23.AB.166.172; 23.AB.166.175; 23.AB.166.240; 23.AB.166.244; 23.AB.169.228; 23.AB.169.229; 23.AB.169.230; 23.AB.169.231; 23.AB.169.236; 23.AB.169.237; 23.AB.169.238; 23.AB.169.239; 23.AB.169.154; 23.AB.169.157; 23.AB.169.166; 23.AB.169.169; 23.AB.169.172; 23.AB.169.175; 23.AB.169.240; 23.AB.169.244; 23.AB.172.228; 23.AB.172.229; 23.AB.172.230; 23.AB.172.231; 23.AB.172.236; 23.AB.172.237; 23.AB.172.238; 23.AB.172.239; 23.AB.172.154; 23.AB.172.157; 23.AB.172.166; 23.AB.172.169; 23.AB.172.172; 23.AB.172.175; 23.AB.172.240; 23.AB.172.244; 23.AB.175.228; 23.AB.175.229; 23.AB.175.230; 23.AB.175.231; 23.AB.175.236; 23.AB.175.237; 23.AB.175.238; 23.AB.175.239; 23.AB.175.154; 23.AB.175.157; 23.AB.175.166; 23.AB.175.169; 23.AB.175.172; 23.AB.175.175; 23.AB.175.24Q; 23.AB.175.244; 23.AB.240.228; 23.AB.240.229; 23.AB.240.230; 23.AB.240.231; 23.AB.240.236; 23.AB.240.237; 23.AB.240.238; 23.AB.240.239; 23.AB.240.154; 23.AB.240.157; 23.AB.240.166; 23.AB.240.169; 23.AB.240.172; 23.AB.240.175; 23.AB.240.240; 23.AB.240.244; 23.AB.244.228; 23.AB.244.229; 23.AB.244.230; 23.AB.244.231; 23.AB.244.236; 23.AB.244.237; 23.AB.244.238; 23.AB.244.239; 23.AB.244.154; 23.AB.244.157; 23.AB.244.166; 23.AB.244.169; 23.AB.244.172; 23.AB.244.175; 23.AB.244.240; 23.AB.244.244;

Prodrugs of 23.BI

23.BI.228.228; 23.BI.228.229; 23.BI.228.230; 23.BI.228.231; 23.BI.228.236; 23.BI.228.237; 23.BI.228.238; 23.BI.228.239; 23.BI.228.154; 23.BI.228.157; 23.BI.228.166; 23.BL228.169; 23.BI.228.172; 23.BI.228.175; 23.BI.228.240; 23.BI.228.244; 23.BI.229.228; 23.BI.229.229; 23.BI.229.230; 23.BI.229.231; 23.BI.229.236; 23.BI.229.237; 23.BI.229.238; 23.BI.229.239; 23.BI.229.154; 23.BI.229.157; 23.BI.229.166; 23.BI.229.169; 23.BI.229.172; 23.BI.229.175; 23.BI.229.240; 23.BI.229.244; 23.BI.230.228; 23.BI.230.229; 23.BI.230.230; 23.BL230.231; 23.BI 230.236; 23.BI.230.237; 23..BI.230.238; 23.BI.230.239; 23.BI.230.154; 23.BI 230.157; 23.BI.230.166; 23,.BI.230.169; 23.BI.230.172; 23.BI.230.175; 23.BI 230.240; 23.BI.230.244; 23,.BI.231.228; 23.BI.231.229; 23.BI.231.230; 23.BI.231.231; 23.BI.231.236;23..BI.231.237;23.BI.231.238; 23.BI.231.239; 23.BI.231.154; 23.BI.231.157; 23,.BI.231.166; 23.BI.231.169; 23.BI.231.172; 23.BI 231.175; 23.BI.231.240; 23,.BI.231.244; 23.BI.236.228; 23.BI.236.229; 23.BI 236.230; 23.BI.236.231; 23,.BI.236.236; 23.BI.236.237; 23.BI.236.238; 23.BI 236.239; 23.BI.236.154; 23,.BI.236.157; 23.BI.236.166; 23.BI.236.169; 23.BI 236.172; 23.BI.236.175; 23.BI.236.240; 23.BI.236.244; 23.BI.237.228; 23.BI ,237.229; 23.BI.237.230; 23,.BI.237.231; 23.BI.237.236; 23.BI.237.237; 23.BI ,237.238; 23.BI.237.239; 23.BI.237.154; 23.BI.237.157; 23.BI.237.166; 23.BI 237.169; 23.BI.237.172;23,.BI.237.175;23.BI.237.240; 23.BI.237.244; 23.BI 238.228; 23.BI.238.229; 23,.BI.238.230; 23.BI.238.231; 23.BI.238.236; 23.BI ,238.237; 23.BI.238.238; 23.BI.238.239; 23.BI.238.154; 23.BI.238.157; 23.BI ,238.166; 23.BI.238.169; 23.BI.238.172; 23.BI.238.175; 23.BI.238.240; 23.BI ,238.244; 23.BI.239.228; 23.BI.239.229; 23.BI.239.230; 23.BI.239.231; 23.BI ,239.236; 23.BI.239.237; 23.BI.239.238; 23.BI.239.239; 23.BI.239.154; 23.BI .239.157; 23.BI.239.166; 23.BI.239.169; 23.BI.239.172; 23.BI.239.175; 23.BI .239.240; 23.BI.239.244; 23.BI.154.228; 23.BI.154.229; 23.BI.154.230; 23.BI ,154.231; 23.BI.154.236;23.BI.154.237; 23.BI.154.238; 23.BI.154.239; 23.BI ,154.154; 23.BI.154.157; 23.BI.154.166; 23.BI154.169; 23.BI.154.172; 23.BI ,154.175; 23.BI.154.240; 23.BI.154.244; 23.BI.157.228; 23.BI.157.229; 23.BI ,157.230; 23.BI.157.231; 23.BI.157.236; 23.BI.157.237; 23.BI.157.238; 23.BI ,157.239; 23.BI.157.154; 23.BI.157.157; 23.BI.157.166; 23.BI.157.169; 23.BI ,157.172; 23.BI.157.175; 23.BI.157.240; 23.BI.157.244; 23.BI.166.228; 23.BI ,166.229; 23.BI.166.230; 23.BI.166.231; 23.BI.166.236; 23.BI.166.237; 23.BI ,166.238; 23.BI.166.239; 23.BI.166.154; 23.BI.166.157; 23.BI.166.166; 23.BI ,166.169; 23.BI.166.172; 23.BI.166.175; 23.BI.166.240; 23.BI166.244; 23.BI 169.228; 23.BI.169.229; 23.BI.169.230; 23.BI.169.231; 23.BI.169.236; 23.BI 169.237; 23.BI.169.238; 23.BI.169.239; 23.BI.169.154; 23.BI.169.157; 23.BI 169.166; 23.BI.169.169; 23.BI.169.172; 23.BI.169.175; 23.BI.169.240; 23.BI 169.244; 23.BI.172.228; 23.BI.172.229; 23.BI.172.230; 23.BI.172.231; 23.BI 172.236; 23.BI.172.237; 23.BI.172.238; 23.BI.172.239; 23.BI.172.154; 23.BI 172.157; 23.BI.172.166; 23.BI.172.169; 23.BI.172.172; 23.BI.172.175; 23.BI ,172.240; 23.BI.172.244; 23.BI.175.228; 23.BI.175.229; 23.BI.175.230; 23.BI ,175.231; 23.BI.175.236; 23.BI.175.237; 23.BI.175.238; 23.BI.175.239; 23.BI 175.154; 23.BI.175.157; 23.BI.175.166; 23.BI.175.169; 23.BI.175.172; 23.BI 175.175; 23.BI.175.240; 23.BI.175.244; 23.BI.240.228; 23.BI.240.229; 23.BI ,240.230; 23.BI.240.231; 23.BI.240.236; 23.BI.240.237; 23.BI.240.238; 23.BI ,240.239; 23.BI.240.154; 23.BI.240.157; 23.BI.240.166; 23.BI.240.169; 23.BI ,240.172; 23.BI.240.175; 23.BI.240.240; 23.BI.240.244; 23.BI.244.228; 23.BI ,244.229; 23.BI.244.230; 23.BI.244.231; 23.BI.244.236; 23.BI.244.237; 23.BI ,244.238; 23.BI.244.239; 23.BI.244.154; 23.BI.244.157; 23.BI.244.166; 23.BL244.169; 23.BI.244.172; 23.BI.244.175; 23.BI.244.240; 23.BI.244.244;

Prodrugs of 23.1

23.1.228.228; 23.1.228.229; 23.1.228.230; 23.1.228.231; 23.1.228.236; 23.1.228.237; 23.1.228.238; 23.1.228.239; 23.1.228.154; 23.1.228.157; 23.1.228.166; 23.1.228.169; 23.1.228.172; 23.1.228.175; 23.1.228.240; 23.1.228.244; 23.1.229.228; 23.1.229.229; 23.1.229.230; 23.1.229.231; 23.1.229.236; 23.1.229.237; 23.1.229.238; 23.1.229.239; 23.1.229.154; 23.1.229.157; 23.1.229.166; 23.1.229.169; 23.1.229.172; 23.1.229.175; 23.1.229.240; 23.1.229.244; 23.1.230.228; 23.1.230.229; 23.1.230.230; 23.1.230.231; 23.1.230.236; 23.1.230.237; 23.1.230.238; 23.1.230.239; 23.1.230.154; 23.1.230.157; 23.1.230.166; 23.1.230.169; 23.1.230.172; 23.1.230.175; 23.1.230.240; 23.1.230.244; 23.1.231.228; 23.1.231.229; 23.1.231.230; 23.1.231.231; 23.1.231.236; 23.1.231.237; 23.1.231.238; 23.1.231.239; 23.1.231.154; 23.1.231.157; 23.1.231.166; 23.1.231.169; 23.1.231.172; 23.1.231.175; 23.1.231.240; 23.1.231.244; 23.1.236.228; 23.1.236.229; 23.1.236.230; 23.1.236.231; 23.1.236.236; 23.1.236.237; 23.1.236.238; 23.1.236.239; 23.1.236.154; 23.1.236.157; 23.1.236.166; 23.1.236.169; 23.1.236.172; 23.1.236.175; 23.1.236.240; 23.1.236.244; 23.1.237.228; 23.1.237.229; 23.1.237.230; 23.1.237.231; 23.1.237.236; 23.1.237.237; 23.1.237.238; 23.1.237.239; 23.1.237.154; 23.1.237.157; 23.1.237.166; 23.1.237.169; 23.1.237.172; 23.1.237.175; 23.1.237.240; 23.1.237.244; 23.1.238.228; 23.1.238.229; 23.1.238.230; 23.1.238.231; 23.1.238.236; 23.1.238.237; 23.1.238.238; 23.1.238.239; 23.1.238.154; 23.1.238.157; 23.1.238.166; 23.1.238.169; 23.1.238.172; 23.1.238.175; 23.1.238.240; 23.1.238.244; 23.1.239.228; 23.1.239.229; 23.1.239.230; 23.1.239.231; 23.1.239.236; 23.1.239.237; 23.1.239.238; 23.1.239.239; 23.1.239.154; 23.1.239.157; 23.1.239.166; 23.1.239.169; 23.1.239.172; 23.1.239.175; 23.1.239.240; 23.1.239.244; 23.1.154.228; 23.1.154.229; 23.1.154.230; 23.1.154.231; 23.1.154.236; 23.1.154.237; 23.1.154.238; 23.1.154.239; 23.1.154.154; 23.1.154.157; 23.1.154.166; 23.1.154.169; 23.1.154.172; 23.1.154.175; 23.1.154.240; 23.1.154.244; 23.1.157.228; 23.1.157.229; 23.1.157.230; 23.1.157.231; 23.1.157.236; 23.1.157.237; 23.1.157.238; 23.1.157.239; 23.1.157.154; 23.1.157.157; 23.1.157.166; 23.1.157.169; 23.1.157.172; 23.1.157.175; 23.1.157.240; 23.1.157.244; 23.1.166.228; 23.1.166.229; 23.1.166.230; 23.1.166.231; 23.1.166.236; 23.1.166.237; 23.1.166.238; 23.1.166.239; 23.1.166.154; 23.1.166.157; 23.1.166.166; 23.1.166.169; 23.1.166.172; 23.1.166.175; 23.1.166.240; 23.1.166.244; 23.1.169.228; 23.1.169.229; 23.1.169.230; 23.1.169.231; 23.1.169.236; 23.1.169.237; 23.1.169.238; 231169.239; 23.1.169.154; 23.1.169.157; 23.1.169.166; 23.1.169.169; 23.1.169.172; 23.1.169.175; 23.1.169.240; 23.1.169.244; 23.1.172.228; 23.1.172.229; 23.1.172.230; 23.1.172.231; 23.1.172.236; 23.1.172.237; 23.1.172.238; 23.1.172.239; 23.1.172.154; 23.1.172.157; 23.1.172.166; 23.1.172.169; 23.1.172.172; 23.1.172.175; 23.1.172.240; 23.1.172.244; 23.1.175.228; 23.1.175.229; 23.1.175.230; 23.1.175.231; 23.1.175.236; 23.1.175.237; 23.1.175.238; 23.1.175.239; 23.1.175.154; 23.1.175.157; 23.1.175.166; 23.1.175.169; 23.1.175.172; 23.1.175.175; 23.1.175.240; 23.1.175.244; 23.1.240.228; 23.1.240-229; 23.1.240.230; 23.1.240.231; 23.1.240.236; 23.1.240.237; 23.1.240.238; 23.1.240.239; 23.1.240.154; 23.1.240.157; 23.1.240.166; 23.1.240.169; 23.1.240.172; 23.1.240.175; 23.1.240.240; 23.1.240.244; 23.1.244.228; 23.1.244.229; 23.1.244.230; 23.1.244.231; 23.1.244.236; 23.1.244.237; 23.1.244.238;23.1.244.239; 23.1.244.154; 23.1.244.157; 23.1.244.166; 23.1.244.169; 23.1.244.172; 23.1.244.175; 23.1.244.240; 23.1.244.244;

Prodrugs of23.T

23.J.228.228; 23.J.228.229; 23.J.228.230;23.J.228.231; 23.J.228.236; 23.J.228.237; 23.J.228.238;23.J.228.239;23.J.228.154;23.J.228.157;23.J.228.166;23.J.228.169; 23.J.228.172; 23.J.228.175; 23.J.228.240; 23.J.228.244; 23.J.229.228; 23.J.229.229; 23.J.229.230; 23.J.229.231; 23.J.229.236; 23.J.229.237; 23.J.229.238; 23.J.229.239; 23.J.229.154;23.J.229.157;23.J.229.166;23.J.229.169;23.J.229.172;23.J.229.175; 23.J.229.240; 23.J.229.244; 23J.230.228; 23.J.230.229; 23.J.230.230; 23.J.23Q.231; 23.J.230.236; 23.J.230.237; 23.J.230.238; 23.J.230.239; 23.J.230.154; 23.J.230.157; 23.J.230.166; 23.J.230.169; 23.J.230.172; 23.J.230.175; 23.J.230.240; 23.J.230.244; 23.J.231.228; 23.J.231.229; 23.J.231.230; 23.J.231.231; 23.J.231.236; 23.J.231.237; 23.J.231.238; 23.J.231.239; 23.J.231.154; 23.J.231.157; 23.J.231.166; 23J.231.169; 23J.231.172; 23J.231.175; 23J.231.240; 23.J.231.244; 23J.236.228; 23J.236.229; 23J.236.230; 23J.236.231; 23J.236.236; 23J.236.237; 23J.236.238; 23J.236.239; 23J.236.154; 23J.236.157; 23.J.236.166; 23J.236.169; 23J.236.172; 23J.236.175; 23J.236.240; 23J.236.244; 23J.237.228; 23J.237.229; 23J.237.230; 23J.237.231; 23J.237.236; 23J.237.237; 23J.237.238;23J.237.239;23J.237.154;23J.237.157; 23J.237.166; 23J.237.169; 23J.237.172; 23J.237.175; 23J.237.240; 23J.237.244; 23J.238.228; 23J.238.229; 23.J.238.23Q; 23J.238.231; 23J.238.236; 23J.238.237; 23J.238.238;23J.238.239; 23J.238.154;23J.238.157;23J.238.166;23J.238.169; 23J.238.172; 23J.238.175; 23J.238.240; 23J.238.244; 23J.239.228; 23J.239.229; 23J.239.230; 23J.239.231; 23J.239.236; 23J.239.237; 23J.239.238; 23.J.239.239; 23J.239.154; 23J.239.157; 23J.239.166; 23J.239.169; 23J.239.172; 23J.239.175; 23.J.239.240; 23J.239.244; 23J.154.228; 23J.154.229; 23.J.154.230; 23J.154.231; 23J.154.236; 23.J.154.237; 23J.154.238; 23J.154.239; 23J.154.154; 23J.154.157; 23J.154.166; 23J.154.169; 23J.154.172; 23J.154.175; 23.J.154.24Q; 23.J.154.244; 23J.157.228; 23J.157.229; 23J.157.230; 23.J.157.231; 23J.157.236; 23J.157.237; 23J.157.238; 23J.157.239; 23J.157.154; 23J.157.157; 23.J.157.166; 23J.157.169; 23J.157.172; 23J.157.175; 23J.157.24Q; 23J.157.244; 23J.166.228; 23J.166.229; 23J.166.230;23J.166.231;23.J.166.236; 23J.166.237;23J.166.238;23J.166.239; 23.J.166.154; 23J.166.157; 23J.166.166; 23J.166.169; 23J.166.172; 23J.166.175; 23J.166.240; 23J.166.244; 23J.169.228; 23J.169.229; 23J.169.230; 23J.169.231; 23.J.169.236;23J.169.237; 23J.169.238;23J.169.239;23J.169.154;23J.169.157; 23J.169.166; 23J.169.169; 23J.169.172; 23J.169.175; 23J.169.240; 23J.169.244; 23J.172.228; 23J.172.229; 23J.172.230; 23J.172.231; 23J.172.236; 23J.172.237; 23J.172.238; 23.J.172.239; 23.J.172.154; 23J.172.157; 23J.172.166; 23J.172.169; 23J.172.172; 23J.172.175; 23J.172.240; 23J.172.244; 23J.175.228; 23J.175.229; 23J.175.230; 23J.175.231; 23J.175.236; 23J.175.237; 23J.175.238; 23J.175.239; 23.J.175.154; 23J.175.157; 23J.175.166; 23.J.175.169; 23J.175.172; 23J.175.175; 23.J.175.240; 23J.175.244; 23J.240.228; 23J.240.229; 23J.240.230; 23J.240.231; 23J.240.236; 23J.240.237; 23J.240.238; 23J.240.239; 23J.240.154; 23J.240.157; 23J.240.166; 23J.240.169; 23J.240.172; 23J.240.175; 23J.240.240; 23J.240.244; 23J.244.228; 23J.244.229;23J.244.230; 23J.244.231; 23J.244.236; 23J.244.237; 23.J.244.238; 23.J.244.239; 23.J.244.154; 23J.244.157; 23.J.244.166; 23.J.244.169; 23.J.244.172; 23.J.244.175; 23.J.244.240; 23J.244.244;

Prodrugs of 23.L

23.L.228.228; 23.L.228.229; 23.L.228.230; 23.L.228.231; 23.L.228.236; 23.L.228.237; 23.L.228.238; 23.L.228.239; 23.L.228.154; 23.L.228.157; 23.L.228.166; 23.L.228.169; 23.L.228.172; 23.L.228.175; 23.L.228.240; 23.L.228.244; 23.L.229.228; 23.L.229.229; 23.L.229.230; 23.L.229.231; 23.L.229.236; 23.L.229.237; 23.L.229.238; 23.L.229.239; 23.L.229.154; 23.L.229.157; 23.L.229.166; 23.L.229.169; 23.L.229.172; 23.L.229.175; 23.L.229.24Q; 23.L.229.244; 23.L.230.228; 23.L.230.229; 23.L.230.230; 23.L.230.231; 23.L.230.236; 23.L.230.237; 23.L.230.238; 23.L.230.239; 23.L.230.154; 23.L.230.157; 23.L.230.166; 23.L.230.169; 23.L.230.172; 23.L.230.175; 23.L.230.240; 23.L.230.244; 23.L.231.228; 23.L.231.229; 23.L.231.230; 23.L.231.231; 23.L.231.236; 23.L.231.237; 23.L.231.238; 23.L.231.239; 23.L.231.154; 23.L.231.157; 23.L.231.166; 23.L.231.169; 23.L.231.172; 23.L.231.175; 23.L.231.240; 23.L.231.244; 23.L.236.228; 23.L.236.229; 23.L.236.230; 23.L.236.231; 23.L.236.236; 23.L.236.237; 23.L.236.238; 23.L.236.239; 23.L.236.154; 23.L.236.157; 23.L.236.166; 23.L.236.169; 23.L.236.172; 23.L.236.175; 23.L.236.240; 23.L.236.244; 23.L.237.228; 23.L.237.229; 23.L.237.230; 23.L.237.231; 23.L.237.236; 23.L.237.237; 23.L.237.238; 23.L.237.239; 23.L.237.154; 23.L.237.157; 23.L.237.166; 23.L.237.169; 23.L.237.172; 23.L.237.175; 23.L.237.240; 23.L.237.244; 23.L.238.228; 23.L.238.229; 23.L.238.230; 23.L.238.231; 23.L.238.236; 23.L.238.237; 23.L.238.238; 23.L.238.239; 23.L.238.154; 23.L.238.157; 23.L.238.166; 23.L.238.169; 23.L.238.172; 23.L.238.175; 23.L.238.240; 23.L.238.244; 23.L.239.228; 23.L.239.229; 23.L.239.230; 23.L.239.231; 23.L.239.236; 23.L.239.237; 23.L.239.238; 23.L.239.239; 23.L.239.154; 23.L.239.157; 23.L.239.166; 23.L.239.169; 23.L.239.172; 23.L.239.175; 23.L.239.240; 23.L.239.244; 23.L.154.228; 23.L.154.229; 23.L.154.230; 23.L.154.231; 23.L.154.236; 23.L.154.237; 23.L.154.238; 23.L.154.239; 23.L.154.154; 23.L.154.157; 23.L.154.166; 23.L.154.169; 23.L.154.172; 23.L.154.175; 23.L.154.240; 23.L.154.244; 23.L.157.228; 23.L.157.229; 23.L.157.230; 23.L.157.231; 23.L.157.236; 23.L.157.237; 23.L.157.238; 23.L.157.239; 23.L.157.154; 23.L.157.157; 23.L.157.166; 23.L.157.169; 23.L.157.172; 23. L.157.175; 23.L.157.240; 23.L.157.244; 23.L.166.228; 23.L.166.229; 23X166.230; 23.L.166.231; 23.L.166.236; 23X.166.237; 23X166.238; 23X166.239; 23X166154; 23.^~L166.157; 23X166166; 23X166169; 23X166172; 23X166175; 23X166.240; 23X166.244; 23X169.228; 23X169.229; 23X169.230; 23X169.231; 23X169.236; 23X169.237; 23X169.238; 23X169.239; 23X169154; 23X169157; 23X169166; 23X169169; 23X169172; 23X169175; 23X169.240; 23X169.244; 23X172.228; 23X172.229; 23X172.230; 23X172.231; 23X172.236; 23X172.237; 23X172.238; 23X172.239; 23X172154; 23X172157; 23X172166; 23X172169; 23X172172; 23X172175; 23X172.240; 23X172.244; 23X175.228; 23X175.229; 23X175.230; 23X175.231; 23X175.236; 23X175.237; 23X175.238; 23X175.239; 23X175154; 23X175157; 23X175166; 23X175169; 23X175172; 23X175175; 23X175.240; 23X175.244; 23X.240.228; 23X.240.229; 23X.240.230; 23X.240.231; 23X.240.236; 23X.240.237; 23X.240.238; 23X.240.239; 23X.240154; 23X.240157; 23X.240166; 23X.240169; 23X.240172; 23X.240175; 23X.240.240; 23X.240.244; 23X.244.228; 23X.244.229; 23X.244.230; 23X.244.231; 23X.244.236; 23.L.244.237; 23.L.244.238; 23.L.244.239; 23.L.244.154; 23.L.244.157; 23.L.244.166; 23.L.244.169; 23.L.244.172; 23.L.244.175; 23.L.244.24Q; 23.L.244.244;

Prodrugs of 23.O

23.O.228.228; 23.O.228.229; 23.O.228.230; 23.O.228.231; 23.O.228.236; 23.O.228.237; 23.O.228.238; 23.O.228.239; 23.O.228.154; 23.O.228.157; 23.O.228.166; 23.O.228.169; 23.O.228.172; 23.O.228.175; 23.O.228.240; 23.O.228.244; 23.O.229.228; 23.O.229.229; 23.O.229.230; 23.O.229.231; 23.O.229.236; 23.O.229.237; 23.O-229.238; 23.O.229.239; 23.O.229.154; 23.O.229.157; 23.O.229.166; 23.O.229.169; 23.O.229.172; 23.O.229.175; 23.O.229.240; 23.O.229.244; 23.O.230.228; 23.O.230.229; 23.O.230.230; 23.O.230.231; 23.O.230.236; 23.O.23Q.237; 23.O.230.238; 23.O.230.239; 23.O.230.154; 23.O.230.157; 23.O.230.166; 23.O.230.169; 23.O.230.172; 23.O.230.175; 23.Q.230.240; 23.O.23Q.244; 23.O.231.228; 23.O.231.229; 23.O.231.230; 23.O.231.231; 23.Q.231.236; 23.O.231.237; 23.O.231.238; 23.O.231.239; 23.O.231.154; 23.O.231.157; 23.O.231.166; 23.O.231.169; 23.0.231.172; 23.O.231.175; 23.O.231.240; 23.O.231.244; 23.O.236.228; 23.O.236.229; 23.O.236.230; 23.O.236.231; 23.O.236.236; 23.O.236.237; 23.O.236.238; 23.O.236.239; 23.O.236.154; 23.O.236.157; 23.O.236.166; 23.O.236.169; 23.O.236.172; 23.O.236.175; 23.O.236.240; 23.O.236.244; 23.O.237.228; 23.O.237.229; 23.O.237.230; 23.O.237.231; 23.O.237.236; 23.O.237.237; 23.O.237.238; 23.O.237.239; 23.O.237.154; 23.O.237.157; 23.O.237.166; 23.O.237.169; 23.O.237.172; 23.O.237.175; 23.O.237.240; 23.O.237.244; 23.Q.238.228; 23.O.238.229; 23.O.238.230; 23.O.238.231; 23.O.238.236; 23.O.238.237; 23.O.238.238; 23.O.238.239; 23.O.238.154; 23.O.238.157; 23.O.238.166; 23.O.238.169; 23.O.238.172; 23.O.238.175; 23.O.238.240; 23.O.238.244; 23.O-239.228; 23.O.239.229; 23.O.239.230; 23.O.239.231; 23.O.239.236; 23.O.239.237; 23.O.239.238; 23.O.239.239; 23.O.239.154; 23.O.239.157; 23.O-239.166; 23.O.239.169; 23.O.239.172; 23.O.239.175; 23.O.239.24Q; 23.O.239.244; 23.O.154.228; 23.O.154.229; 23.O.154.230; 23.O.154.231; 23.O.154.236; 23.O.154.237; 23.O.154.238; 23.O.154.239; 23.O.154.154; 23.O.154.157; 23.O.154.166; 23.O.154.169; 23.O.154.172; 23.O.154.175; 23.O.154.240; 23.O.154.244; 23.O.157.228; 23.O.157.229; 23.O.157.230; 23.O.157.231; 23.O.157.236; 23.O.157.237; 23.O.157.238; 23.O.157.239; 23.O.157.154; 23.O.157.157; 23.O.157.166; 23.O.157.169; 23.O.157.172; 23.O.157.175; 23.O.157.240; 23.O.157.244; 23.O.166.228; 23.O.166.229; 23.O.166.230; 23.O.166.231; 23.O.166.236; 23.O.166.237; 23.O.166.238; 23.O.166.239; 23.O.166.154; 23.O.166.157; 23.O.166.166; 23.O.166.169; 23.O.166.172; 23.O.166.175; 23.O.166.240; 23.O.166.244; 23.O.169.228; 23.O.169.229; 23.O.169.230; 23.O.169.231; 23.O.169.236; 23.O.169.237; 23.O.169.238; 23.O.169.239; 23.O.169.154; 23.O.169.157; 23.O.169.166; 23.O.169.169; 23.O.169.172; 23.O.169.175; 23.O.169.240; 23.O.169.244; 23.O.172.228; 23.O.172.229; 23.O.172.230; 23.O.172.231; 23.O.172.236; 23.O.172.237; 23.O.172.238; 23.O.172.239; 23.O.172.154; 23.O.172.157; 23.O.172.166; 23.O.172.169; 23.O.172.172; 23.O.172.175; 23.O.172.240; 23.O.172.244; 23.O.175.228; 23.O.175.229; 23.O.175.230; 23.O.175.231; 23.O.175.236; 23.O.175.237; 23.O.175.238; 23.O.175.239; 23.O.175.154; 23.O.175.157; 23.O.175.166; 23.O.175.169; 23.O.175.172; 23.O.175.175; 23.O.175.240; 23.O.175.244; 23.O.240.228; 23.O.240.229; 23.O.24Q.230; 23.O.240.231; 23.O.240.236; 23.O.240.237; 23.O.240.238; 23.O.240.239; 23.O.240.154; 23.O.240.157; 23.O.240.166; 23.O.240.169; 23.O.240.172; 23.O.240.175; 23.O.240.240; 23.O.240.244; 23.O.244.228; 23.O.244.229; 23.O.244.230; 23.O.244.231; 23.O.244.236; 23.O.244.237; 23.O.244.238; 23.O.244.239; 23.O.244.154; 23.O.244.157; 23.O.244.166; 23.O.244.169; 23.O.244.172; 23.O.244.175; 23.O.244.240; 23.O.244.244;

Prodrugs of 23.P

23.P.228.228; 23.P.228.229; 23.P.228.230; 23.P.228.231; 23.P.228.236; 23.P.228.237; 23.P.228.238; 23.P.228.239; 23.P.228.154; 23.P.228.157; 23.P.228.166; 23.P.228.169; 23.P.228.172; 23.P.228.175; 23.P.228.240; 23.P.228.244; 23.P.229.228; 23.P.229.229; 23.P.229.230; 23.P.229.231; 23.P.229.236; 23.P.229.237; 23.P.229.238; 23.P.229.239; 23.P.229.154; 23.P.229.157; 23.P.229.166; 23.P.229.169; 23.P.229.172; 23.P.229.175; 23.P.229.240; 23.P.229.244; 23.P.230.228; 23.P.230.229; 23.P.230.230; 23.P.230.231; 23.P.230.236; 23.P.230.237; 23.P.230.238; 23.P.230.239; 23.P.230.154; 23.P.230.157; 23.P.230.166; 23.P.230.169; 23.P.230.172; 23.P.230.175; 23.P.230.240; 23.P.230.244; 23.P.231.228; 23.P.231.229; 23.P.231.230; 23.P.231.231; 23.P.231.236; 23.P.231.237; 23.P.231.238; 23.P.231.239; 23.P.231.154; 23.P.231.157; 23.P.231.166; 23.P.231.169; 23.P.231.172; 23.P.231.175; 23.P.231.240; 23.P.231.244; 23.P.236.228; 23.P.236.229; 23.P.236.230; 23.P.236.231; 23.P.236.236; 23.P.236.237; 23.P.236.238; 23.P.236.239; 23.P.236.154; 23.P.236.157; 23.P.236.166; 23.P.236.169; 23.P.236-172; 23.P.236.175; 23.P.236.240; 23.P.236.244; 23.P.237.228; 23.P.237.229; 23.P.237.230; 23.P.237.231; 23.P.237.236; 23.P.237.237; 23.P.237.238; 23.P.237.239; 23.P.237.154; 23.P.237.157; 23.P.237.166; 23.P.237.169; 23.P.237.172; 23.P.237.175; 23.P.237.240; 23.P.237.244; 23.P.238.228; 23.P.238.229; 23.P.238.230; 23.P.238.231; 23.P.238.236; 23.P.238.237; 23.P.238.238; 23.P.238.239; 23.P.238.154; 23.P.238.157; 23.P.238.166; 23.P.238.169; 23.P.238.172; 23.P.238.175; 23.P.238.240; 23.P.238.244; 23.P.239.228; 23.P.239.229; 23.P.239.230; 23.P.239.231; 23.P.239.236; 23.P.239.237; 23.P.239.238; 23.P.239.239; 23.P.239.154; 23.P.239.157; 23.P.239.166; 23.P.239.169; 23.P.239.172; 23.P.239.175; 23.P.239.240; 23.P.239.244; 23.P.154.228; 23.P.154.229; 23.P.154.230; 23.P.154.231; 23.P.154.236; 23.P.154.237; 23.P.154.238; 23.P.154.239; 23.P.154.154; 23.P.154.157; 23.P.154.166; 23.P.154.169; 23.P.154.172; 23.P.154.175; 23.P.154.240; 23.P.154.244; 23.P.157.228; 23.P.157.229; 23.P.157.230; 23.P.157.231; 23.P.157.236; 23.P.157.237; 23.P.157.238; 23.P.157.239; 23.P.157.154; 23.P.157.157; 23.P.157.166; 23.P.157.169; 23.P.157.172; 23.P.157.175; 23.P.157.240; 23.P.157.244; 23.P.166.228; 23.P.166.229; 23.P.166.230; 23.P.166.231; 23.P.166.236; 23.P.166.237; 23.P.166.238; 23.P.166.239; 23.P.166.154; 23.P.166.157; 23.P.166.166; 23.P.166.169; 23.P.166.172; 23.P.166.175; 23.P.166.240; 23.P.166.244; 23.P.169.228; 23.P.169.229; 23.P.169.230; 23.P.169.231; 23.P.169.236; 23.P.169.237; 23.P.169.238; 23.P.169.239; 23.P.169.154; 23.P.169.157; 23.P.169.166; 23.P.169.169; 23.P.169.172; 23.P.169.175; 23.P.169.240; 23.P.169.244; 23.P.172.228; 23.P.172.229; 23.P.172.230; 23.P.172.231; 23.P.172.236; 23.P.172.237; 23.P.172.238; 23.P.172.239; 23.P.172.154; 23.P.172.157; 23.P.172.166; 23.P.172.169; 23.P.172.172; 23.P.172.175; 23.P.172.240; 23.P.172.244; 23.P.175.228; 23.P.175.229; 23.P.175.230; 23.P.175.231; 23.P.175.236; 23.P.175.237; 23.P.175.238; 23.P.175.239; 23.P.175.154; 23.P.175.157; 23.P.175.166; 23.P.175.169; 23.P.175.172; 23.P.175.175; 23.P.175.240; 23.P.175.244; 23.P.240.228; 23.P.240.229; 23.P.240.230; 23.P.240.231; 23.P.240.236; 23.P.240.237; 23.P.240.238; 23.P.240.239; 23.P.240.154; 23.P.240.157; 23.P.240.166; 23.P.240.169; 23.P.240.172; 23.P.240.175; 23.P.240.240; 23.P.240.244; 23.P.244.228; 23.P.244.229; 23.P.244.230; 23.P.244.231; 23.P.244.236; 23.P.244.237; 23.P.244.238; 23.P.244.239; 23.P.244.154; 23.P.244.157; 23.P.244.166; 23.P.244.169; 23.P.244.172; 23.P.244.175; 23.P.244.240; 23.P.244.244;

Prodrugs of 23.U

23.U.228.228; 23.U.228.229; 23.U.228.230; 23.U.228.231; 23.U.228.236; 23.U.228.237; 23.U.228.238; 23.U.228.239; 23.U.228.154; 23.U.228.157; 23.U.228.166; 23.U.228.169; 23.U.228.172; 23.U.228.175; 23.U.228.240; 23.U.228.244; 23.U.229.228; 23.U.229.229; 23.U.229.230; 23.U.229.231; 23.U.229.236; 23.U.229.237; 23.U.229.238; 23.U.229.239; 23.U.229.154; 23.U.229.157; 23.U.229.166; 23.U.229.169; 23.U.229.172; 23.U.229.175; 23.U.229.240; 23.U.229.244; 23.U.230.228; 23.U.230.229; 23.U.230.230; 23.U.230.231; 23.U.230.236; 23.U.230.237; 23.U.230.238; 23.U.230.239; 23.U.230.154; 23.U.23Q.157; 23.U.230.166; 23.U.230.169; 23.U.230.172; 23.U.230.175; 23.U.230.240; 23.U.230.244; 23.U.231.228; 23.U.231.229; 23.U.231.230; 23.U.231.231; 23.U.231.236; 23.U. ,231..237; 23.U.231.238; 23.U.231.239; 23.U.231.154; 23.U.231.157; 23.U.231.166; 23.U. ,231..169; 23.U.231.172; 23.U.231.175; 23.U.231.240; 23.U.231.244; 23.U.236.228; 23.U.236.229; 23.U.236.230; 23.U.236.231; 23.U.236.236; 23.U.236.237; 23.U.236.238; 23.U.236.239; 23.U.236.154; 23.U.236.157; 23.U.236.166; 23.U.236.169; 23.U.236.172; 23.U.236.175; 23.U.236.24Q; 23.U.236.244; 23.U.237.228; 23.U.237.229; 23.U.237.230; 23.U.237.231; 23.U.237.236; 23.U.237.237; 23.U.237.238; 23.U.237.239; 23.U.237.154; 23.U.237.157; 23.U.237.166; 23.U.237.169; 23.U.237.172; 23.U.237.175; 23.U.237.240; 23.U.237.244; 23.U.238.228; 23.U.238.229; 23.U.238.230; 23.U.238.231; 23.U.238.236; 23.U.238.237; 23.U.238.238; 23.U.238.239; 23.U-238.154; 23.U.238.157; 23.U.238.166; 23.U.238.169; 23.U.238.172; 23.U.238.175; 23.U.238.240; 23.U.238.244; 23.U.239.228; 23.U.239.229; 23.U.239.230; 23.U.239.231; 23.U.239.236; 23.U.239.237; 23.U.239.238; 23.U.239.239; 23.U.239.154; 23.U.239.157; 23.U.239.166; 23.U. ,239. ,169; 23.U.239.172; 23.U.239.175; 23.U.239.240; 23.U.239.244; 23.U.154.228; 23.U.154.229; 23.U.154.230; 23.U.154.231; 23.U.154.236; 23.U.154.237; 23.U.154.238; 23.U.154.239; 23.U.154.154; 23.U.154.157; 23.U.154.166; 23.U.154.169; 23.U.154.172; 23.U.154.175; 23.U.154.240; 23.U.154.244; 23.U.157.228; 23.U.157.229; 23.U.157.230; 23.U.157.231; 23.U.157.236; 23.U.157.237; 23.U.157.238; 23.U.157.239; 23.U.157.154; 23.U.157.157; 23.U.157.166; 23.U.157.169; 23.U.157.172; 23.U.157.175; 23.U.157.240; 23.U.157.244; 23.U.166.228; 23.U.166.229; 23.U.166.230; 23.U.166.231; 23.U.166.236; 23.U.166.237; 23.U.166.238; 23.U.166.239; 23.U.166.154; 23.U.166.157; 23.U.166.166; 23.U.166.169; 23.U.166.172; 23.U.166175; 23.U.166.240; 23.U.166.244; 23.U.169.228; 23.U.169.229; 23.U.169.230; 23.U.169.231; 23.U.169.236; 23.U.169.237; 23.U.169.238; 23.U.169.239; 23.U.169.154; 23.U.169.157; 23.U.169.166; 23.U.169.169; 23.U.169.172; 23.U.169.175; 23.U.169.240; 23.U.169.244; 23.U.172.228; 23.U.172.229; 23.U.172.230; 23.IJ.172.231; 23.U.172.236; 23.U.172.237; 23.U.172.238; 23.U.172.239; 23.U.172.154; 23.U.172.157; 23.U.172.166; 23.U.172.169; 23.U.172.172; 23.U.172.175; 23.U.172.240; 23.U.172.244; 23.U.175.228; 23.U.175.229; 23.U.175.230; 23.U.175.231; 23.U.175.236; 23.U.175.237; 23.U.175.238; 23.U.175.239; 23.U.175.154; 23.U.175.157; 23.U.175.166; 23.U.175.169; 23.U.175.172; 23.U.175.175; 23.U.175.240; 23.U.175.244; 23.U.240.228; 23.U.240.229; 23.U.240.230; 23.U.240.231; 23.U.240.236; 23.U.240.237; 23.U.24Q.238; 23.U.240.239; 23.U.240.154; 23.U.240.157; 23.U.240.166; 23.U.240.169; 23.U.240.172; 23.U.240.175; 23.U.24Q.240; 23.U.240.244; 23.U.244.228; 23.U.244.229; 23.U.244.230; 23.U.244.231; 23.U.244.236; 23.U.244.237; 23.U-244.238; 23.U.244.239; 23.U.244.154; 23.U.244.157; 23.U.244.166; 23.U.244.169; 23.U.244.172; 23.U.244.175; 23.U.244.240; 23.U.244.244;

Prodrugs of 23.CD

23.CD.228.228; 23.CD.228.229; 23.CD.228.230; 23.CD.228.231; 23.CD.228.236; 23.CD.228.237; 23.CD.228.238; 23.CD.228.239; 23.CD.228.154; 23.CD.228.157; 23.CD.228.166; 23.CD.228.169; 23.CD.228.172; 23.CD.228.175; 23.CD.228.240; 23.CD.228.244; 23.CD.229.228; 23.CD.229.229; 23.CD.229.230; 23.CD.229.231; 23.CD.229.236; 23.CD.229.237; 23.CD.229.238; 23.CD.229.239; 23. CD.22915k, 23.CD.229.157; 23.CD.229.166; 23.CD.229.169; 23.CD.229.172; 23.CD.229.175; 23.CD.229.240; 23.CD.229.244; 23.CD.230.228; 23.CD.230.229; 23.CD.230.230; 23.CD.230.231; 23.CD.230.236; 23.CD.230.237; 23.CD.230.238; 23.CD.230.239; 23.CD.230.154; 23.CD.230.157; 23.CD.230.166; 23.CD.230.169; 23.CD.230.172; 23.CD.230.175; 23.CD.230.240; 23.CD.230.244; 23.CD.231.228; 23. CD.231.229; 23.CD.231.230; 23.CU231.231; 23.CD.231.236; 23.CD.231.237; 23.CD.231.238; 23.CD.231.239; 23.CD.231.154; 23-CD.231.157; 23.CD.231.166; 23.CD.231.169; 23.CD.231.172; 23. CD.231.175; 23.CD.231.240; 23.CD.231.244; 23.CD.236.228; 23.CD.236.229; 23.CD.236.230; 23.CD.236.231; 23.CD.236.236; 23.CD.236.237; 23.CD.236.238; 23.CD.236.239; 23.CD.236.154; 23.CD.236.157; 23.CD.236.166; 23.CD.236.169; 23.CD.236.172; 23.CD.236.175; 23.CD.236.240; 23.CD.236.244; 23.CD.237.228; 23.CD.237.229; 23.CD.237.230; 23.CD.237.231; 23.CD.237.236; 23.CD.237.237; 23.CD.237.238; 23.CD.237.239; 23.CD.237.154; 23.CD.237.157; 23.CD.237.166; 23.CD.237.169; 23.CD.237.172; 23.CD.237.175; 23.CD.237.240; 23.CD.237.244; 23.CD.238.228; 23.CD.238.229; 23.CD.238.230; 23.CD.238.231; 23.CD.238.236; 23.CD.238.237; 23.CD.238.238; 23.CD.238.239; 23.CD.238.154; 23.CD.238.157; 23.CD.238.166; 23.CD.238.169; 23.CD.238.172; 23.CD.238.175; 23.CD.238.240; 23.CD.238.244; 23.CD.239.228; 23.CD.239.229; 23.CD.239.230; 23.CD.239.231; 23.CD.239.236; 23.CD.239.237; 23.CD.239.238; 23.CD.239.239; 23.CD.239.154; 23.CD.239.157; 23.CD.239.166; 23.CD.239.169; 23.CD.239.172; 23.CD.239.175; 23.CD.239.240; 23.CD.239.244; 23.CD.154.228; 23.CD.154.229; 23.CD.154.230; 23.CD.154.231; 23.CD.154.236; 23.CD.154.237; 23.CD.154.238; 23.CD.154.239; 23.CD.154.154; 23.CD.154.157; 23.CD.154.166; 23.CD.154.169; 23.CD.154.172; 23.CD.154.175; 23.CD.154.240; 23.CD.154.244; 23.CD.157.228; 23.CD.157.229; 23.CD.157.230; 23.CD.157.231; 23.CD.157.236; 23.CD.157.237; 23.CD.157.238; 23.CD.T57.239; 23.CD.157.154; 23.CD.157.157; 23.CD.157.166; 23.CD.157.169; 23.CD.157.172; 23.CD.157.175; 23.CD.157.240; 23. CD.157.24.4;,' 23.CD.166.228; 23.CD.166.229; 23.CD.166.230; 23.CD.166.231; 23.CD.166.236; 23.CD.166.237; 23.CD.166.238; 23. CD.166.239; 23.CD.166.154; 23.CD.166.157; 23.CD.166.166; 23.CD.166.169; 23.CD.166.172; 23.CD.166.175; 23.CD.166.240; 23.CD.166.244; 23.CD.169.228; 23.CD.169.229; 23.CD.169.230; 23.CD.169.231; 23.CD.169.236; 23.CD.169.237; 23.CU169.238; 23.CD.169.239; 23.CD.169.154; 23.CD.169.157; 23.CD.169.166; 23.CD.169.169; 23.CD.169.172; 23.CD.169.175; 23.CD.169.240; 23.CD.169.244; 23.CD.172.228; 23.CD.172.229; 23.CD.172.230; 23.CD.172.231; 23.CD.172.236; 23.CD.172.237; 23.CD.172.238; 23.CD.172.239; 23.CD.172.154; 23.CD.172.157; 23.CD.172.166; 23.CD.172.169; 23.CD.172.172; 23.CD.172.175; 23.CD.172.240; 23.CD.172.244; 23.CD.175.228; 23.CD.175.229; 23.CD.175.230; 23.CD.175.231; 23.CD.175.236; 23.CD.175.237; 23.CD.175.238; 23.CD.175.239; 23.CD.175.154; 23.CD.175.157; 23.CD.175.166; 23.CD.175.169; 23.CD.175.172; 23.CD.175.175; 23.CD.175.240; 23.CD.175.244; 23.CD.240.228; 23.CD.240.229; 23.CD.240.230; 23.CD.240.231; 23.CD.24Q.236; 23.CD.24Q.237; 23.CD.240.238; 23.CD.240.239; 23.CD.240.154; 23.CD.240.157; 23.CD.240.166; 23.CD.240.169; 23.CD.240.172; 23.CD.240.175; 23.CD.240-240; 23.CD.240.244; 23.CD.244.228; 23.CD.244.229; 23.CD.244.230; 23.CD.244.231; 23.CD.244.236; 23.CD.244.237; 23.CD.244.238; 23.CD.244.239; 23.CD.244.154; 23.CD.244.157; 23.CD.244.166; 23.CD.244.169; 23.CD.244.172; 23.CD.244.175; 23.CD.244.240; 23.CD.244.244;

Prodrugs of 23.EB

23.EB.228.228; 23.EB.228.229; 23.EB.228.230; 23.EB.228.231; 23.EB.228.236; 23.EB.228.237; 23.EB.228.238; 23. EB.228.239; 23.EB.228.154; 23.EB.228.157; 23.EB.228.166; 23.EB.228.169; 23. EB.228.172; 23.EB.228.175; 23.EB.228.240; 23.EB.228.244; 23.EB.229.228; 23.EB.229.229; 23. EB.229.230; 23.EB.229.231; 23.EB.229.236; 23.EB.229.237; 23.EB.229.238; 23.EB.229.239; 23.EB.229.154; 23.EB.229.157; 23.EB.229.166; 23.EB.229.169; 23.EB.229.172; 23.EB.229.175; 23.EB.229.240; 23.EB.229.244; 23.EB.230.228; 23.EB.230.229; 23.EB.230.230; 23.EB.230.231; 23.EB.230.236; 23.EB.230.237; 23.EB.230.238; 23.EB.230.239; 23.EB.230.154; 23.EB.230.157; 23.EB.230.166; 23.EB.23Q.169; 23.EB.230.172; 23.EB.230.175; 23.EB.230.240; 23.EB.230.244; 23.EB.231.228; 23.EB.231.229; 23.EB.231.230; 23.EB.231.231; 23.EB.231.236; 23.EB.231.237; 23.EB.231.238; 23.EB.231.239; 23.EB.231.154; 23.EB.231.157; 23.EB.231.166; 23.EB.231.169; 23.EB.231.172; 23.EB.231.175; 23.EB.231.240; 23.EB.231.244; 23.EB.236.228; 23.EB.236.229; 23.EB.236.230; 23.EB.236.231; 23.EB.236.236; 23.EB.236.237; 23.EB.236.238; 23.EB.236.239; 23.EB.236.154; 23.EB.236.157; 23.EB.236.166; 23.EB.236.169; 23.EB.236.172; 23.EB.236.175; 23.EB.236.240; 23.EB.236.244; 23.EB.237.228; 23.EB.237.229; 23.EB.237.230; 23.EB.237.231; 23.EB.237.236; 23.EB.237.237; 23.EB.237.238; 23.EB.237.239; 23.EB.237.154; 23.EB.237.157; 23.EB.237.166; 23. EB.237.169; 23.EB.237.172; 23.EB.237.175; 23. EB.237.240; 23.EB.237.244; 23.EB.238.228; 23.EB.238.229; 23.EB.238.230; 23.EB.238.231; 23.EB.238.236; 23.EB.238.237; 23.EB.238.238; 23.EB.238.239; 23.EB.238.154; 23.EB.238.157; 23.EB.238.166; 23.EB.238.169; 23.EB.238.172; 23.EB.238.175; 23.EB.238.240; 23.EB.238.244; 23.EB.239.228; 23.EB.239.229; 23.EB.239.230; 23.EB.239.231; 23.EB.239.236;23.EB.239.237; 23.EB.239.238; 23.EB.239.239; 23.EB.239.154; 23.EB.239.157; 23.EB.239.166; 23.EB.239.169; 23.EB.239.172; 23.EB.239.175; 23.EB.239.240;23.EB.239.244;23.EB.154.228; 23.EB.154.229; 23.EB.154.230; 23.EB.154.231; 23.EB.154.236; 23.EB.154.237; 23.EB.154.238; 23.EB.154.239; 23.EB.154.154; 23.EB.154.157; 23.EB.154.166; 23.EB.154.169; 23.EB.154.172; 23.EB.154.175; 23.EB.154.240; 23.EB.154.244; 23.EB.157.228; 23.EB.157.229; 23.EB.157.23Q; 23.EB.157.231; 23.EB.157.236; 23.EB.157.237; 23.EB.157.238; 23.EB.157.239; 23.EB.157.154; 23.EB.157.157; 23.EB.157.166; 23.EB.157.169; 23.EB.157.172; 23.EB.157.175; 23.EB.157.240; 23.EB.157.244; 23.EB.166.228; 23.EB.166.229; 23.EB.166.230; 23.EB.166.231; 23.EB.166.236; 23.EB.166.237;23.EB.166.238;23.EB.166.239;23.EB.166.154; 23.EB.166.157; 23.EB.166.166; 23.EB.166.169; 23.EB.166.172; 23.EB.166.175; 23.EB.166.240; 23.EB.166.244; 23.EB.169.228; 23.EB.169.229; 23.EB.169.230; 23.EB.169.231; 23.EB.169.236; 23.EB.169.237; 23.EB.169.238; 23.EB.169.239; 23.EB.169.154; 23.EB.169.157; 23.EB.169.166; 23.EB.169.169; 23.EB.169.172; 23.EB.169.175; 23.EB.169.240; 23.EB.169.244; 23.EB.172.228; 23.EB.172.229; 23.EB.172.230; 23.EB.172.231; 23.EB.172.236; 23.EB.172.237; 23.EB.172.238; 23.EB.172.239; 23.EB.172.154; 23.EB.172.157; 23.EB.172.166; 23.EB.172.169; 23.EB.172.172; 23.EB.172.175; 23.EB.172.240;23.EB.172.244; 23.EB.175.228; 23.EB.175.229; 23.EB.175.230; 23.EB.175.231; 23.EB.175.236; 23.EB.175.237; 23.EB.175.238; 23.EB.175.239; 23.EB.175.154; 23.EB.175.157; 23.EB.175.166; 23.EB.175.169; 23.EB.175.172; 23.EB.175.175; 23.EB.175.240; 23.EB.175.244; 23.EB.240.228; 23.EB.240.229; 23.EB.240.230; 23.EB.240.231; 23.EB.240.236; 23.EB.240.237; 23.EB.240.238; 23.EB.240.239; 23.EB.240.154; 23.EB.240.157; 23.EB.240.166; 23.EB.240.169; 23.EB.240.172; 23.EB.24Q.175; 23.EB.240.240; 23.EB.240.244; 23.EB.244.228; 23.EB.244.229; 23.EB.244.230; 23.EB.244.231; 23.EB.244.236; 23.EB.244.237; 23.EB.244.238;23.EB-244.239;23.EB.244.154; 23.EB.244.157; 23.EB.244.166; 23.EB.244.169; 23.EB.244.172; 23.EB.244.175; 23.EB.244.240; 23.EB.244.244;

Prodrugs of24.B

24.B.228.228; 24.B.228.229; 24.B.228.230; 24.B.228.231; 24.B.228.236; 24.B.228.237; 24.B.228.238; 24.B.228.239; 24.B.228.154; 24.B.228.157; 24.B.228.166; 24.B.228.169; 24.B.228.172; 24.B.228.175; 24.B.228.240; 24.B.228.244; 24.B.229.228; 24.B.229.229; 24.B.229.230; 24.B.229.231; 24.B.229.236; 24.B.229.237; 24.B.229.238; 24.B.229.239; 24.B.229.154; 24.B.229.157; 24.B.229.166; 24.B.229.169; 24.B.229.172; 24.B.229.175; 24.B.229.240; 24.B.229.244; 24.B.230.228; 24.B.230.229; 24.B.230.230; 24.B.230.231; 24.B.230.236; 24.B.230.237; 24.B.230.238; 24.B.230.239; 24.B.230.154; 24.B.230.157; 24.B.230.166; 24.B.230.169; 24.B.230.172; 24.B.230.175; 24.B.230.240; 24.B.230.244; 24.B.231.228; 24.B.231.229; 24.B.231.230; 24.B.231.231; 24.B.231.236; 24.B.231.237; 24.B.231.238; 24.B.231.239; 24.B.231.154; 24.B.231.157; 24.B.231.166; 24.B.231.169; 24.B.231.172; 24.B.231.175; 24.B.231.240; 24.B.231.244; 24.B.236.228; 24.B.236.229; 24.B.236.230; 24.B.236.231; 24.B.236.236; 24.B.236.237; 24.B.236.238; 24.B.236.239; 24.B.236.154; 24.B.236.157; 24.B.236.166; 24.B.236.169; 24.B.236.172; 24.B.236.175; 24.B.236.240; 24.B.236.244; 24.B.237.228; 24.B.237.229; 24.B.237.230; 24.B.237.231; 24.B.237.236; 24.B.237.237; 24.B.237.238; 24.B.237.239; 24.B.237.154; 24.B.237.157; 24.B.237.166; 24.B.237.169; 24.B.237.172; 24.B.237.175; 24.B.237.240; 24.B.237.244; 24.B.238.228; 24.B.238.229; 24.B.238.230; 24.B.238.231; 24.B.238.236; 24.B.238.237; 24.B.238.238; 24.B.238.239; 24.B.238.154; 24.B.238.157; 24.B.238.166; 24.B.238.169; 24.B.238.172; 24.B.238.175; 24.B.238.240; 24.B.238.244; 24.B.239.228; 24.B.239.229; 24.B.239.230; 24.B.239.231; 24.B.239.236; 24.B.239.237; 24.B.239.238; 24.B.239.239; 24.B.239.154; 24.B.239.157; 24.B.239.166; 24.B.239.169; 24.B.239.172; 24.B.239.175; 24.B.239.240; 24.B.239.244; 24.B.154.228; 24.B.154.229; 24.B.154.230; 24.B.154.231; 24.B.154.236; 24.B.154.237; 24.B.154.238; 24.B.154.239; 24.B.154.154; 24.B.154.157; 24.B.154.166; 24.B.154.169; 24.B.154.172; 24.B.154.175; 24.B.154.240; 24.B.154.244; 24.B.157.228; 24.B.157.229; 24.B.157.230; 24.B.157.231; 24.B.157.236; 24.B.157.237; 24.B.157.238; 24.B.157.239; 24.B.157.154; 24.B.157.157; 24.B.157.166; 24.B.157.169; 24.B.157.172; 24.B.157.175; 24.B.157.240; 24.B.157.244; 24.B.166.228; 24.B.166.229; 24.B.166.230; 24.B.166.231; 24.B.166.236; 24.B.166.237; 24.B.166.238; 24.B.166.239; 24.B.166.154; 24.B.166.157; 24.B.166.166; 24.B.166.169; 24.B.166.172; 24.B.166.175; 24.B.166.240; 24.B.166.244; 24.B.169.228; 24.B.169.229; 24.B.169.230; 24.B.169.231; 24.B.169.236; 24.B.169.237; 24.B.169.238; 24.B.169.239; 24.B.169.154; 24.B.169.157; 24.B.169.166; 24.B.169.169; 24.B.169.172; 24.B.169.175; 24.B.169.240; 24.B.169.244; 24.B.172.228; 24.B.172.229; 24.B.172.230; 24.B.172.231; 24.B.172.236; 24.B.172.237; 24.B.172.238; 24.B.172.239; 24.B.172.154; 24.B.172.157; 24.B.172.166; 24.B.172.169; 24.B.172.172; 24.B.172.175; 24.B.172.240; 24.B.172.244; 24.B.175.228; 24.B.175.229; 24.B.175.23Q; 24.B.175.231; 24.B.175.236; 24.B.175.237; 24.B.175.238; 24.B.175.239; 24.B.175.154; 24.B.175.157; 24.B.175.166; 24.B.175.169; 24.B.175.172; 24.B.175.175; 24.B.175.240; 24.B.175.244; 24.B.240.228; 24.B.240.229; 24.B.240.230; 24.B.240.231; 24.B.240.236; 24.B.240.237; 24.B.240.238; 24.B.240.239; 24.B.240.154; 24.B.24Q.157; 24.B.24Q.166; 24.B.240.169; 24.B.240.172; 24.B.240.175; 24.B.240.240; 24.B.240.244; 24.B.244.228; 24.B.244.229; 24.B.244.230; 24.B.244.231; 24.B.244.236; 24.B.244.237; 24.B.244.238; 24.B.244.239; 24.B.244.154; 24.B.244.157; 24.B.244.166; 24.B.244.169; 24.B.244.172; 24.B.244.175; 24.B.244.240; 24.B.244.244;

Prodrugs of 24.D

24.D.228.228; 24.D.228.229; 24.D.228.230; 24.D.228.231; 24.D.228.236; 24.D.228.237; 24.D.228.238; 24.D.228.239; 24.D.228.154; 24.D.228.157; 24.D.228.166; 24.D.228.169; 24.U228.172; 24.D.228.175; 24.D.228.240; 24.D.228.244; 24.D.229.228; 24.D.229.229; 24.D.229.230; 24.D.229.231; 24.D.229.236; 24.D.229.237; 24.D.229.238; 24.D.229.239; 24.D.229.154; 24.D.229.157; 24.D.229.166; 24.D.229.169; 24.D.229.172; 24.D.229.175; 24.D.229.240; 24.D.229.244; 24.D.230.228; 24.D.230.229; 24.D.230.230; 24.D.230.231; 24.D.230.236; 24.D.230.237; 24.D.230.238; 24.D.230.239; 24.D.230.154; 24.D.230.157; 24.D.230.166; 24.D.230.169; 24.D.230.172; 24.D.230.175; 24.D.230.240; 24.D.230.244; 24.D.231.228; 24.D.231.229; 24.D.231.230; 24.D.231.231; 24.D.231.236; 24.D.231.237; 24.D.231.238; 24.D.231.239; 24.D.231.154; 24.D.231.157; 24.D.231.166; 24.D.231.169; 24.D.231.172; 24.D.231.175; 24.D.231.240; 24.D.231.244; 24.D.236.228; 24.D.236.229; 24.D.236.230; 24.D.236.231; 24.D.236.236; 24.D.236.237; 24.D.236.238; 24.D.236.239; 24.D.236.154; 24.D.236.157; 24.D.236.166; 24.D.236.169; 24.D.236.172; 24.D.236.175; 24.D.236.240; 24.D.236.244; 24.D.237.228; 24.D.237.229; 24.D.237.230; 24.D.237.231; 24.D.237.236; 24.D.237.237; 24.D.237.238; 24.D.237.239; 24.D.237.154; 24.D.237.157; 24.D.237.166; 24.D.237.169; 24.D.237.172; 24.D.237.175; 24.D.237.240; 24.D.237.244; 24.D.238.228; 24.D.238.229; 24.D.238.230; 24.D.238.231; 24.D.238.236; 24.D.238.237; 24.D.238.238; 24.D.238.239; 24.D.238.154; 24.D.238.157; 24.D.238.166; 24.D.238.169; 24.D.238.172; 24.D.238.175; 24.D.238.240; 24.D.238.244; 24.D.239.228; 24.D.239.229; 24.D.239.230; 24.D.239.231; 24.D.239.236; 24.D.239.237; 24.D.239.238; 24.D.239.239; 24.D.239.154; 24.D.239.157; 24.D.239.166; 24.D.239.169; 24.D.239.172; 24.D.239.175; 24.D.239.240; 24.D.239.244; 24.D.154.228; 24.D.154.229; 24.D.154.230; 24.D.154.231; 24.D.154.236; 24.D.154.237; 24.D.154.238; 24.D.154.239; 24.D.154.154; 24.D.154.157; 24.D.154.166; 24.D.154.169; 24.D.154.172; 24.D.154.175; 24.D.154.240; 24.D.154.244; 24.D.157.228; 24.D.157.229; 24.D.157.230; 24.D.157.231; 24.D.157.236; 24.D.157.237; 24.D.157.238; 24.D.157.239; 24.D.157.154; 24.D.157.157; 24.D.157.166; 24.D.157.169; 24.D.157.172; 24.D.157.175; 24.D.157.240; 24.D.157.244; 24.D.166.228; 24.D.166.229; 24.D.166.230; 24.D.166.231; 24.D.166.236; 24.D.166.237; 24.D.166.238; 24.D.166.239; 24.D.166.154; 24.D.166.157; 24.D.166.166; 24.D.166.169; 24.D.166.172; 24.D.166.175; 24.D.166.240; 24.D.166.244; 24.D.169.228; 24.D.169.229; 24.D.169.230; 24.D.169.231; 24.D.169.236; 24.D.169.237; 24.D.169.238; 24.D.169.239; 24.D.169.154; 24.D.169.157; 24.D.169.166; 24.D.169.169; 24.D.169.172; 24.D.169.175; 24.D.169.240; 24.U169.244; 24.D.172.228; 24.D.172.229; 24.D.172.230; 24.D.172.231; 24.D.172.236; 24.D.172.237; 24.D.172.238; 24.D.172.239; 24.D.172.154; 24.D.172.157; 24.D.172.166; 24.D.172.169; 24.D.172.172; 24.D.172.175; 24.D.172.240; 24.D.172.244; 24.D.175.228; 24.D.175.229; 24.D.175.230; 24.D.175.231; 24.D.175.236; 24.D.175.237; 24.D.175.238; 24.D.175.239; 24.D.175.154; 24.D.175.157; 24.D.175.166; 24.D.175.169; 24.D.175.172; 24.D.175.175; 24.D.175.240; 24.D.175.244; 24.D.240.228; 24.D.240.229; 24.D.240.230; 24.D.240.231; 24.D.240.236; 24.D.240.237; 24.D.240.238; 24.D.240.239; 24.D.240.154; 24.D.240.157; 24.D.240.166; 24.D.240.169; 24.D.240.172; 24.D.240.175; 24.D.240.240; 24.D.240.244; 24.D.244.228; 24.D.244.229; 24.D.244.230; 24.D.244.231; 24.D.244.236; 24.D.244.237; 24.D.244.238; 24.D.244.239; 24.D.244.154; 24.D.244.157; 24.D.244.166; 24.D.244.169; 24.D.244.172; 24.D.244.175; 24.D.244.240; 24.D.244.244;

Prodrugs of 24.AB

24.AB.228.228; 24.AB.228.229; 24.AB.228.230; 24.AB.228.231; 24.AB.228.236; 24.AB.228.237; 24.AB.228.238; 24.AB.228.239; 24.AB.228.154; 24.AB.228.157; 24.AB.228.166; 24.AB.228.169; 24.AB.228.172; 24.AB.228.175; 24.AB.228.240; 24.AB.228.244; 24.AB.229.228; 24.AB.229.229; 24.AB.229.230; 24.AB.229.231; 24.AB.229.236; 24.AB.229.237; 24. AB.229.238; 24.AB.229.239; 24. AB.229..154; 24.AB.229.157; 24.AB.229.166; 24.AB.229.169; 24.AB.229.172; 24.AB.229.175; 24.AB.229.240; 24.AB.229.244; 24.AB.230.228; 24.AB.230.229; 24.AB.230.230; 24.AB.230.231; 24.AB.230.236; 24.AB.23Q.237; 24.AB.230.238; 24.AB.230.239; 24.AB.230.154; 24.AB.230.157; 24.AB.230.166; 24.AB.230.169; 24.AB.230.172; 24.AB.230.175; 24.AB.230.240; 24. AB.230.244; 24.AB.231.228; 24. AB .231.229; 24.AB.231.230; 24.AB.231.231; 24.AB.231.236; 24.AB.231.237; 24.AB.231.238; 24.AB.231.239; 24.AB.231.154; 24.AB.231.157; 24.AB.231.166; 24.AB.231.169; 24.AB.231.172; 24.AB.231.175; 24.AB.231.240; 24.AB.231.244; 24.AB.236.228; 24.AB.236.229; 24.AB.236.230; 24.AB.236.231; 24.AB.236.236; 24.AB.236.237; 24.AB.236.238; 24.AB.236.239; 24.AB.236.154; 24.AB.236.157; 24.AB.236.166; 24.AB.236.169; 24.AB.236.172; 24.AB.236.175; 24.AB.236.240; 24.AB.236.244; 24.AB.237.228; 24. AB.237.229; 24.AB.237.230; 24.AB.237.231; 24.AB.237.236; 24.AB.237.237; 24.AB.237.238; 24.AB.237.239; 24.AB.237.154; 24.AB.237.157; 24.AB.237.166; 24.AB.237.169; 24.AB.237.172; 24.AB.237.175; 24.AB.237.24Q; 24.AB.237.244; 24. AB .238.228; 24.AB.238.229; 24.AB.238.230; 24.AB.238.231; 24.AB.238.236; 24.AB.238.237; 24.AB.238.238; 24.AB.238.239; 24.AB.238.154; 24.AB.238.157; 24.AB.238.166; 24.AB.238.169; 24.AB.238.172; 24.AB.238.175; 24.AB.238.240; 24.AB.238.244; 24. AB .239.228; 24.AB.239.229; 24.AB.239.230; 24.AB.239.231; 24. AB.239.236; 24.AB.239.237; 24.AB.239.238; 24. AB.239.239; 24.AB.239.154; 24.AB.239.157; 24.AB.239.166; 24.AB.239.169; 24.AB.239.172; 24.AB.239.175; 24.AB.239.240; 24.AB.239.244; 24.AB.154.228; 24.AB.154.229; 24.AB.154.230; 24.AB.154.231; 24.AB.154.236; 24.AB.154.237; 24.AB.154.238; 24.AB.154.239; 24.AB.154.154; 24.AB.154.157; 24.AB.154.166; 24.AB.154.169; 24.AB.154.172; 24.AB.154.175; 24.AB.154.24Q; 24.AB.154.244; 24.AB.157.228; 24.AB.157.229; 24.AB.157.230; 24.AB.157.231; 24.AB.157.236; 24.AB.157.237; 24.AB.157.238; 24.AB.157.239; 24.AB.157.154; 24.AB-157.157; 24.AB.157.166; 24.AB.157.169; 24.AB.157.172; 24.AB.157.175; 24.AB.157.240; 24.AB.157.244; 24.AB.166.228; 24.AB.166.229; 24.AB.166.23Q; 24.AB.166-231; 24.AB.166.236; 24.AB.166.237; 24.AB.166.238; 24.AB.166.239; 24.AB.166.154; 24.AB.166.157; 24.AB.166.166; 24.AB.166.169; 24.AB.166.172; 24.AB.166.175; 24.AB.166.240; 24.AB.166.244; 24.AB.169.228; 24.AB.169.229; 24.AB.169.230; 24.AB.169.231; 24.AB.169.236; 24.AB.169.237; 24.AB.169.238; 24.AB.169.239; 24.AB.169.154; 24.AB.169.157; 24.AB.169.166; 24.AB.169.169; 24.AB.169.172; 24.AB.169.175; 24.AB.169.240; 24.AB.169.244; 24.AB.172.228; 24.AB.172.229; 24.AB.172.230; 24.AB.172.231; 24.AB.172.236; 24.AB.172.237; 24.AB.172.238; 24.AB.172.239; 24.AB.172.154; 24.AB.172.157; 24.AB.172.166; 24.AB.172.169; 24.AB.172.172; 24.AB.172.175; 24.AB.172.240; 24.AB.172.244; 24.AB.175.228; 24.AB.175.229; 24.AB.175.230; 24.AB.175.231; 24.AB.175.236; 24.AB.175.237; 24.AB.175.238; 24.AB.175.239; 24.AB.175.154; 24.AB.175.157; 24.AB.175.166; 24.AB.175.169; 24.AB.175.172; 24.AB.175.175; 24. AB.175.240; 24.AB.175.244; 24.AB.240.228; 24.AB.240.229; 24.AB.240.230; 24.AB.240.231; 24.AB.240.236; 24.AB.240.237; 24.AB.240.238; 24.AB.240.239; 24.AB.240.154; 24.AB.240.157; 24.AB.240.166; 24.AB.240.169; 24. AB.240.172; 24.AB.240.175; 24.AB.240.240; 24.AB.240.244; 24.AB.244.228; 24.AB.244.229; 24.AB.244.230; 24.AB.244.231; 24.AB.244.236; 24.AB.244.237; 24.AB.244.238; 24.AB.244.239; 24.AB.244.154; 24.AB.244.157; 24.AB.244.166; 24.AB.244.169; 24.AB.244.172; 24.AB.244.175; 24. AB.244.240; 24.AB.244.244;

Prodrugs of 24.BI

24.BI.228.228; 24.BI.228.229; 24.BI.228.230; 24.BI.228.231; 24.BI.228.236; 24.BI.228.237; 24.BI.228.238; 24.BL228.239; 24.BI.228.154; 24.BI.228.157; 24.BI.228.166; 24.BI.228.169; 24.BI.228.172; 24.BI.228.175; 24.BI.228.240; 24.BI.228.244; 24.BI.229.228; 24.BI.229.229; 24.BI.229.230; 24.BI.229.231; 24.BI.229.236; 24.BI.229.237; 24.BI.229.238; 24.BI.229.239; 24.BI.229.154; 24.BI.229.157; 24.BI.229.166; 24.BI.229.169; 24.BI.229.172; 24.BI.229.175; 24.BI.229.240; 24.BI.229.244; 24.BI.230.228; 24.BI.230.229; 24.BI.230.230; 24.BI.230.231; 24.BI.230.236; 24.BI.230.237; 24.BI.23Q.238; 24.BI.230.239; 24.BI.230.154; 24.BI.23Q.157; 24.BL230.166; 24.BI.230.169; 24.BI.230.172; 24.BI.230.175; 24.BI.230.240; 24.BI.230.244; 24.BI.231.228; 24.BI.231.229; 24.BI.231.230; 24.BI.231.231; 24.BI.231.236; 24.BI.231.237; 24.BI.231.238; 24.BI.231.239; 24.BI.231.154; 24.BI.231.157; 24.BI.231.166; 24.BI.231.169; 24.BI.231.172; 24.BI.231.175; 24.BI.231.240; 24.BI.231.244; 24.BI.236.228; 24.BI.236.229; 24.BI.236.230; 24.BI.236.231; 24.BI.236.236; 24.BI.236.237; 24.BI.236.238; 24.BI.236.239; 24.BI.236.154; 24.BI.236.157; 24.BI.236.166; 24.BI.236.169; 24.BI.236.172; 24.BI.236.175; 24.BL236.240; 24.BI.236.244; 24.BI.237.228; 24.BI.237.229; 24.BI.237.230; 24.BI.237.231; 24.BI.237.236; 24.BI.237.237; 24.BI.237.238; 24.BI.237.239; 24.BI.237.154; 24.BI.237.157; 24.BI.237.166; 24.BI.237.169; 24.BI.237.172; 24.BI.237.175; 24.BI.237.240; 24.BI.237.244; 24.BI.238.228; 24.BI.238.229; 24.BI.238.230; 24.BI.238.231; 24.BI.238.236; 24.BI.238.237; 24.BL238.238; 24.BI.238.239; 24.BI.238.154; 24.BI.238.157; 24.BI.238.166; 24.BI.238.169; 24.BI.238.172; 24.BI.238.175; 24.BI.238.240; 24.BI.238.244; 24.BI.239.228; 24.BI.239.229; 24.BI.239.230; 24.BI.239.231; 24.BI.239.236; 24.BI.239.237; 24.BI.239.238; 24.BI.239.239; 24.BI.239.154; 24.BI.239.157; 24.BI.239.166; 24.BI.239.169; 24.BI.239.172; 24.BI.239.175; 24.BI.239.240; 24.BI.239.244; 24.BI.154.228; 24.BI.154.229; 24.BI.154.230; 24.BI.154.231; 24.BI.154.236; 24.BI.154.237; 24.BI.154.238; 24.BI.154.239; 24.BI.154.154; 24.BI.154.157; 24.BI.154.166; 24.BI.154.169; 24.BI.154.172; 24.BI.154.175; 24.BI.154.240; 24.BI.154.244; 24.BI.157.228; 24.BI.157.229; 24.BI.157.230; 24.BI.157.231; 24.BI.157.236; 24.BI.157.237; 24.BI.157.238; 24.BI.157.239; 24.BI.157.154; 24.BI.157.157; 24.BI.157.166; 24.BI.157.169; 24.BI.157.172; 24.BI.157.175; 24.BI.157.240; 24.BI.157.244; 24.BI.166.228; 24.BI.166.229; 24.BI.166.230; 24.BI.166.231; 24.BI.166.236; 24.BI.166.237; 24.BI.166.238; 24.BI.166.239; 24.BI.166.154; 24.BI.166.157; 24.BI.166.166; 24.BI.166.169; 24.BI.166.172; 24.BI.166.175; 24.BI.166.240; 24.BL166.244; 24.BI.169.228; 24.BI.169.229; 24.BI.169.230; 24.BI.169.231; 24.BI.169.236; 24.BI.169.237; 24.BI.169.238; 24.BI.169.239; 24.BI.169.154; 24.BI.169.157; 24.BI.169.166; 24.BI.169.169; 24.BI.169.172; 24.BI.169.175; 24.BI.169.240; 24.BI.169.244; 24.BI.172.228; 24.BI.172.229; 24.BI.172.230; 24.BI.172.231; 24.BI.172.236; 24.BI.172.237; 24.BI.172.238; 24.BI.172.239; 24.BI.172.154; 24.BI.172.157; 24.BI.172.166; 24÷BI.Y72.169; 24.BI.172.172; 24.BI.172.175; 24.BL172.240; 24.BI.172.244; 24.BL175.228; 24.BI.175.229; 24.BI.175.230; 24.BI.175.231; 24.BI.175.236; 24.BI.175.237; 24.BI.175.238; 24.BI.175.239; 24.BI.175.154; 24.BI.175.157; 24.BI.175.166; 24.BI.175.169; 24.BI.175.172; 24.BI.175.175; 24.BI.175.240; 24.BI.175.244; 24.BI.240.228; 24.BI.240.229; 24.BI.240.230; 24.BI.240.231; 24.BI.240.236; 24.BI.240.237; 24.BI.240.238; 24.BI.240.239; 24.BI.240.154; 24.BI.240.157; 24.BI.240.166; 24.BI.240.169; 24.BI.240.172; 24.BI.240.175; 24.BI.240.240; 24.BI.240.244; 24.BI.244.228; 24.BI.244.229; 24.BI.244.23Q; 24.BI.244.231; 24.BI.244.236; 24.BI.244.237; 24.BI.244.238; 24.BI.244.239; 24.BI.244.154; 24.BI.244.157; 24.BI.244.166; 24.BI.244.169; 24.BI.244.172; 24.BI.244.175; 24.BI.244.240; 24.BI.244.244;

Prodrugs of 24.1

24.1.228.228; 24.1.228.229; 24.1.228.230; 24.1.228.231; 24.1.228.236; 24.1.228.237; 24.1.228.238; 24.1.228.239; 24.1.228.154; 24.1.228.157; 24.1.228.166; 24.1.228.169; 24.1.228.172; 24.1.228.175; 24.1.228.240; 24.1.228.244; 24.1.229.228; 24.1.229.229; 24.1.229.230; 24.1.229.231; 24.1.229.236; 24.1.229.237; 24.1.229.238; 24.1.229.239; 24.1.229.154; 24.1.229.157; 24.1.229.166; 24.1.229.169; 24.1.229.172; 24.1.229.175; 24.1.229.240; 24.1.229.244; 24.1.230.228; 24.1.230.229; 24.1.230.230; 24.1.230-231; 24.1.230.236; 24.1.230.237; 24.1.230.238; 24.1.230.239; 24.1.230.154; 24.1.230.157; 24.1.230.166; 24.1.230.169; 24.1.230.172; 24.1.230.175; 24.1.230.240; 24.1.230.244; 24.1.231.228; 24.1.231.229; 24.1.231.230; 24.1.231.231; 24.1.231.236; 24.1.231.237; 24.1.231.238; 24.1.231.239; 24.1.231.154; 24.1.231.157; 24.1.231.166; 24.1.231.169; 24.1.231.172; 24.1.231.175; 24.1.231.240; 24.1.231.244; 24.1.236.228; 24.1.236.229; 24.1.236.230; 24.1.236.231; 24.1.236.236; 24.1.236.237; 24.1.236.238; 24.1.236.239; 24.1.236.154; 24.1.236.157; 24.1.236.166; 24.1.236.169; 24.1.236.172; 24.1.236.175; 24.1.236.240; 24.1.236.244; 24.1.237.228; 24.1.237.229; 24.1.237.230; 24.1.237.231; 24.1.237.236; 24.1.237.237; 24.1.237.238; 24.1.237.239; 24.1.237.154; 24.1.237.157; 24.1.237.166; 24.1.237.169; 24.1.237.172; 24.1.237.175; 24.1.237.240; 24.1.237.244; 24.1.238.228; 24.1.238.229; 24.1.238.230; 24.1.238.231; 24.1.238.236; 24.1.238.237; 24.1.238.238; 24.1.238.239; 24.1.238.154; 24.1.238.157; 24.1.238.166; 24.1.238.169; 24.1.238.172; 24.1.238.175; 24.1.238.240; 24.1.238.244; 24.1.239.228; 24.1.239.229; 24.1.239.230; 24.1.239.231; 24.1.239.236; 24.1.239.237; 24.1.239.238; 24.1.239.239; 24.1.239.154; 24.1.239.157; 24.1.239.166; 24.1.239.169; 24.1.239.172; 24.1.239.175; 24.1.239.240; 24.1.239.244; 24.1.154.228; 24.1.154.229; 24.1.154.230; 24.1.154.231; 24.1.154.236; 24.1.154.237; 24.1.154.238; 24.1.154.239; 24.1.154.154; 24.1.154.157; 24.1.154.166; 24.1.154.169; 24.1.154.172; 24.1.154.175; 24.1.154.240; 24.1.154.244; 24.1.157.228; 24.1.157.229; 24.1.157.230; 24.1.157.231; 24.1.157.236; 24.1.157.237; 24.1.157.238; 24.1.157.239; 24.1.157.154; 24.1.157.157; 24.1.157.166; 24.1.157.169; 24.1.157.172; 24.1.157.175; 24.1.157.240; 24.1.157.244; 24.1.166.228; 24.1.166.229; 24.1.166.230; 24.1.166.231; 24.1.166.236; 24.1.166.237; 24.1.166.238; 24.1.166.239; 24.1.166.154; 24.1.166.157; 24.1.166.166; 24.1.166.169; 24.1.166.172; 24.1.166.175; 24.1.166.240; 24.1.166.244; 24.1.169.228; 24.1.169.229; 24.1.169.230; 24.1.169.231; 24.1.169.236; 24.1.169.237; 24.1.169.238; 24.1.169.239; 24.1.169.154; 24.1.169.157; 24.1.169.166; 24.1.169.169; 24.1.169.172; 24.1.169.175; 24.1.169.240; 24.1.169.244; 24.1.172.228; 24.1.172.229; 24.1.172.230; 24.1.172.231; 24.1.172.236; 24.1.172.237; 24.1.172.238; 24.1.172.239; 24.1.172.154; 24.1.172.157; 24.1.172.166; 24.1.172.169; 24.1.172.172; 24.1.172.175; 24.1.172.240; 24.1.172.244; 24.1.175.228; 24.1.175.229; 24.1.175.230;24.1.175.231;24.1.175.236;24.1.175.237;24.1.175.238;24.1.175.239; 24.1.175.154; 24.1.175.157; 24.1.175.166; 24.1.175.169; 24.1.175.172; 24.1.175.175; 24.1.175.240; 24.1.175.244; 24.1.240.228; 24.1.240.229; 24.1.240.230; 24.1.240.231; 24.1.240.236; 24.1.240.237; 24.1.240.238; 24.1.240.239; 24.1.240.154; 24.1.240.157; 24.1.240.166; 24.1.240.169; 24.1.240.172; 24.1.240.175; 24.1.240.240; 24.1.240.244; 24.1.244.228; 24.1.244.229; 24.1.244.230; 24.1.244.231; 24.1.244.236; 24.1.244.237; 24.1.244.238; 24.1.244.239; 24.1.244.154; 24.1.244.157; 24.1.244.166; 24.1.244.169; 24.1.244.172; 24.1.244.175; 24.1.244.240; 24.1.244.244;

Prodrugs of24.T

24.J.228.228; 24.J.228.229; 24.J.228.230; 24.J.228.231; 24.J.228.236; 24.J.228.237; 24.J.228.238; 24.J.228.239;24.J.228.154;24.J.228.157;24.J.228.166;24.J.228.169; 24.J.228.172; 24.J.228.175; 24.J.228.240; 24.J.228.244; 24.J.229.228; 24.J.229.229; 24.J.229.230; 24.J.229.231;24.J.229.236;24.J.229.237;24.J.229.238;24.J.229.239; 24.J.229.154; 24.J.229.157; 24.J.229.166; 24.J.229.169; 24.J.229.172; 24.J.229.175; 24.J.229.240; 24.J.229.244; 24.J.230.228; 24.J.230.229; 24.J.230.230; 24.J.230.231; 24.J.230.236; 24.J.230.237; 24.J.230.238; 24.J.230.239; 24.J.230.154; 24.J.230.157; 24.J.230.166; 24J.^'230.169; 24.J.230.172; 24.J.230.175; 24.J.230.240; 24.J.230.244; 24.J.231.228; 24.J.231.229; 24.J.231.230; 24J.231.231; 24.J.231.236; 24.J.231.237; 24.J.231.238; 24.J.231.239; 24.J.231.154; 24.J.231.157; 24.J.231.166; 24.J.231.169; 24.J.231.172; 24.J.231.175; 24.J.231.240; 24.J.231.244; 24.J.236.228; 24.J.236.229; 24.J.236.230; 24.J.236.231; 24.J.236.236; 24.J.236.237; 24.J.236.238; 24.J.236.239; 24.J.236.154; 24.J.236.157; 24.J.236.166; 24.J.236.169; 24.J.236.172; 24.J.236.175; 24.J.236.240; 24.J.236.244; 24.J.237.228; 24.J.237.229; 24.J.237.230; 24.J.237.231; 24.J.237.236; 24.J.237.237;24.J.237.238;24J.237.239; 24.J.237.154;24J.237.157; 24J.237.166; 24.J.237.169; 24J.237.172; 24.J.237.175; 24.J.237.24Q; 24.J.237.244; 24J.238.228; 24J.238.229; 24J.238.230;24J.238.231; 24J.238.236; 24J.238.237; 24J.238.238; 24J.238.239; 24J.238.154; 24.J.238.157; 24J.238.166; 24.J.238.169; 24.J.238.172; 24J.238.175; 24J.238.240; 24J.238.244; 24.J.239.228; 24J.239.229; 24J.239.230; 24J.239.231; 24.J.239.236; 24J.239.237; 24J.239.238; 24J.239.239; 24J.239.154; 24J.239.157; 24J.239.166; 24J.239.169; 24J.239.172; 24J.239.175; 24J.239.240; 24J.239.244; 24J.154.228; 24J.154.229; 24J.154.230; 24J.154.231; 24J.154.236; 24J.154.237; 24J.154.238; 24.J.154.239; 24J.154.154; 24J.154.157; 24.J.154.166; 24J.154.169; 24J.154.172; 24J.154.175; 24.J.154.240; 24J.154.244; 24J.157.228; 24J.157.229; 24J.157.230; 24J.157.231; 24J.157.236; 24.J.157.237; 24J.157.238; 24J.157.239; 24J.157.154; 24J.157.157; 24J.157.166; 24J.157.169; 24.J.157.172; 24J.157.175; 24J.157.240; 24J.157.244; 24J.166.228; 24.J.166.229; 24J.166.230;24J.166.231; 24J.166.236; 24.J.166.237; 24J.166.238;24J.166.239; 24J.166.154; 24J.166.157; 24J.166.166; 24J.166.169; 24J.166.172; 24J.166.175; 24J.166.240;24J.166.244; 24.J.169.228;24J.169.229; 24J.169.230; 24J.169.231; 24J.169.236; 24J.169.237; 24J.169.238; 24.J.169.239; 24J.169.154; 24J.169.157; 24J.169.166; 24J.169.169;24J.169.172;24J.169.175;24J.169.240;24.J.169.244; 24J.172.228; 24.J.172.229; 24J.172.230; 24J.172.231; 24J.172.236; 24J.172.237; 24J.172.238; 24J.172.239; 24J.172.154; 24.J.172.157; 24J.172.166; 24J.172.169; 24.J.172.172; 24J.172.175; 24J.172.240; 24J.172.244; 24J.175.228; 24J.175.229; 24.J.175.230; 24.J.175.231; 24.J.175.236; 24.J.175.237; 24.J.175.238; 24.J.175.239; 24.J.175.154; 24.J.175.157; 24.J.175.166; 24.J.175.169; 24.J.175.172; 24.J.175.175; 24.J.175.240; 24.J.175.244; 24.J.240.228; 24.J.240.229; 24.J.240.230; 24J.240.231; 24.J.240.236; 24.J.240.237; 24.J.240.238; 24.J.240.239; 24.J.240.154; 24.J.240.157; 24.J.240.166; 24.J.240.169; 24.J.240.172; 24J.240.175; 24.J.240.240; 24.J.240.244; 24.J.244.228; 24.J.244.229; 24.J.244.230; 24J.244.231; 24J.244.236; 24J.244.237; 24.J.244.238; 24J.244.239; 24J.244.154; 24.J.244.157; 24J.244.166; 24J.244.169; 24J.244.172; 24J.244.175; 24J.244.240; 24J.244.244;

Prodrugs of 24.L

24.L.228.228; 24.L.228.229; 24.L.228.230; 24.L.228.231; 24.L.228.236; 24.L.228.237; 24.L.228.238; 24.L.228.239; 24.L.228.154; 24.L.228.157; 24.L.228.166; 24.L.228.169; 24.L.228.172; 24.L.228.175; 24.L.228.240; 24.L.228.244; 24.L.229.228; 24.L.229.229; 24.L.229.230; 24.L.229.231; 24.L.229.236; 24.L.229.237; 24.L.229.238; 24.L.229.239; 24.L.229.154; 24.L.229.157; 24.L.229.166; 24.L.229.169; 24.L.229.172; 24.L.229.175; 24.L.229.240; 24.L.229.244; 24.L.230.228; 24.L.230.229; 24.L.230.230; 24.L.230.231; 24.L.230.236; 24.L.230.237; 24.L.230.238; 24.L.230.239; 24.L.230.154; 24.L.230.157; 24.L.230.166; 24.L.230.169; 24.L.230.172; 24.L.230.175; 24.L.230.240; 24.L.230.244; 24.L.231.228; 24.L.231.229; 24.L.231.230; 24.L.231.231; 24.L.231.236; 24.L.231.237; 24.L.231.238; 24.L.231.239; 24.L.231.154; 24.L.231.157; 24.L.231.166; 24.L.231.169; 24.L.231.172; 24.L.231.175; 24.L.231.240; 24.L.231.244; 24.L.236.228; 24.L.236.229; 24.L.236.230; 24.L.236.231; 24.L.236.236; 24.L.236.237; 24.L.236.238; 24.L.236.239; 24X.236.154; 24.L.236.157; 24.L.236.166; 24.L.236.169; 24.L.236.172; 24.L.236.175; 24.L.236.240; 24.L.236.244; 24.L.237.228; 24.L.237.229; 24.L.237.230; 24.L.237.231; 24.L.237.236; 24.L.237.237; 24.L.237.238; 24.L.237.239; 24.L.237.154; 24.L.237.157; 24.L.237.166; 24.L.237.169; 24.L.237.172; 24.L.237.175; 24.L.237.240; 24.L.237.244; 24.L.238.228; 24.L.238.229; 24.L.238.230; 24.L.238.231; 24.L.238.236; 24.L.238.237; 24.L.238.238; 24.L.238.239; 24.L.238.154; 24.L.238.157; 24.L.238.166; 24.L.238.169; 24.L.238.172; 24.L.238.175; 24.L.238.240; 24.L.238.244; 24.L.239.228; 24.L.239.229; 24.L.239.230; 24.L.239.231; 24.L.239.236; 24.L.239.237; 24.L.239.238; 24.L.239.239; 24.L.239.154; 24.L.239.157; 24.L.239.166; 24.L.239.169; 24.L.239.172; 24.L.239.175; 24.L.239.240; 24.L.239.244; 24.L.154.228; 24.L.154.229; 24.L.154.230; 24.L.154.231; 24.L.154.236; 24.L.154.237; 24.L.154.238; 24.L.154.239; 24.L.154.154; 24.L.154.157; 24.L.154.166; 24.L.154.169; 24.L.154.172; 24.L.154.175; 24.L.154.240; 24.L.154.244; 24.L.157.228; 24.L.157.229; 24.L.157.230; 24.L.157.231; 24.L.157.236; 24.L.157.237; 24.L.157.238; 24.L.157.239; 24.L.157.154; 24.L.157.157; 24.L.157.166; 24.L.157.169; 24.L.157.172; 24.L.157.175; 24.L.157.240; 24.L.157.244; 24.L.166.228; 24.L.166.229; 24.L.166.230; 24.L.166.231; 24.L.166.236; 24.L.166.237; 24.L.166.238; 24.L.166.239; 24.L.166.154; 24.L.166.157; 24.L.166.166; 24.L.166.169; 24.L.166.172; 24.L.166.175; 24.L.166.240; 24.L.166.244; 24.L.169.228; 24.L.169.229; 24.L.169.230; 24.L.169.231; 24.L.169.236; 24.L.169.237; 24.L.169.238; 24.L.169.239; 24.L.169.154; 24.L.169.157; 24.L.169.166; 24.L.169.169; 24.L.169.172; 24.L.169.175; 24.L.169.240; 24.L.169.244; 24.L.172.228; 24.L.172.229; 24.L.172.230; 24.L.172.231; 24.L.172.236; 24.L.172.237; 24.L.172.238; 24.L.172.239; 24.L.172.154; 24.L.172.157; 24.L.172.166; 24.L.172.169; 24.L.172.172; 24.L.172.175; 24.L.172.240; 24.L.172.244; 24.L.175.228; 24.L.175.229; 24.L.175.230; 24.L.175.231; 24.L.175.236; 24.L.175.237; 24.L.175.238; 24.L.175.239; 24.L.175.154; 24.L.175.157; 24.L.175.166; 24.L.175.169; 24.L.175.172; 24.L.175.175; 24.L.175.240; 24.L.175.244; 24.L.24Q.228; 24.L.240.229; 24.L.240.230; 24.L.240.231; 24.L.240.236; 24.L.240.237; 24.L.240.238; 24.L.240.239; 24.L.240.154; 24.L.24Q.157; 24.L.240.166; 24.L.240.169; 24.L.240.172; 24.L.240.175; 24.L.240.240; 24.L.240.244; 24.L.244.228; 24.L.244.229; 24.L.244.230; 24.L.244.231; 24.L.244.236; 24.L.244.237; 24.L.244.238; 24.L.244.239; 24.L.244.154; 24.L.244.157; 24.L.244.166; 24.L.244.169; 24.L.244.172; 24.L.244.175; 24.L.244.240; 24.L.244.244;

Prodrugs of 24.O

24.O.228.228; 24.O.228.229; 24.O.228.230; 24.O.228.231; 24.O.228.236; 24.0.228.237; 24.O.228.238; 24.O.228.239; 24.O.228.154; 24.O.228.157; 24.O.228.166; 24.O.228.169; 24.O.228.172; 24.O.228.175; 24.O.228.240; 24.O.228.244; 24.O.229.228; 24.O.229.229; 24.O.229.230; 24.O.229.231; 24.O.229.236; 24.O.229.237; 24.O.229.238; 24.O.229.239; 24.O.229.154; 24.O.229.157; 24.O.229.166; 24.O.229.169; 24.O.229.172; 24.O.229.175; 24.O.229.240; 24.O.229.244; 24.O.230.228; 24.O.230-229; 24.O.230.230; 24.O.230.231; 24.Q.230.236; 24.O.230.237; 24.O.230.238; 24.O.230.239; 24.O.230.154; 24.O.230.157; 24.O.230.166; 24.O.230.169; 24.O.230.172; 24.O.23Q.175; 24.O.230.240; 24.O.230.244; 24.O.231.228; 24.O.231.229; 24.O.231.230; 24.O.231.231; 24.O.231.236; 24.O.231.237; 24.O.231.238; 24.O.231.239; 24.O.231.154; 24.O.231.157; 24.O.231.166; 24.O.231.169; 24.O.231.172; 24.O.231.175; 24.O.231.240; 24.O.231.244; 24.O-236.228; 24.O.236.229; 24.O-236.230; 24.O.236.231; 24.O.236.236; 24.O.236.237; 24.O.236.238; 24.O.236.239; 24.O-236.154; 24.O.236.157; 24.O.236.166; 24.O.236.169; 24.O-236.172; 24.O.236.175; 24.O.236.24Q; 24.O.236.244; 24.O.237.228; 24.O.237.229; 24.O.237.230; 24.O.237.231; 24.O.237.236; 24.O.237.237; 24.O-237.238; 24.O.237.239; 24.O.237.154; 24.O.237.157; 24.O.237.166; 24.O.237.169; 24.O.237.172; 24.O.237.175; 24.O.237.240; 24.O.237.244; 24.O.238.228; 24.O.238.229; 24.O.238.230; 24.O.238.231; 24.O.238.236; 24.O.238.237; 24.O.238.238; 24.O.238.239; 24.O.238.154; 24.O.238.157; 24.O.238.166; 24.O.238.169; 24.O.238.172; 24.O.238.175; 24.O.238.240; 24.O.238.244; 24.O.239.228; 24.O.239.229; 24.O.239.230; 24.O.239.231; 24.O.239.236; 24.O.239.237; 24.O.239.238; 24.O.239.239; 24.O.239.154; 24.O.239.157; 24.O.239.166; 24.O.239.169; 24.O.239.172; 24.O.239.175; 24.O.239.240; 24.O.239.244; 24.O.154.228; 24.O.154.229; 24.O.154.230; 24.O.154.231; 24.O.154.236; 24.O.154.237; 24.O.154.238; 24.O.154.239; 24.O.154.154; 24.O.154.157; 24.O.154.166; 24.O.154.169; 24.O.154.172; 24.O.154.175; 24.O.154.240; 24.O.154.244; 24.O.157.228; 24.O.157.229; 24.O.157.230; 24.O.157.231; 24.O.157.236; 24.O.157.237; 24.O.157.238; 24.O.157.239; 24.O.157.154; 24.O.157.157; 24.O.157.166; 24.O.157.169; 24.O.157.172; 24.O.157.175; 24.O-157.240; 24.O.157.244; 24.O.166.228; 24.O.166.229; 24.O.166.230; 24.O.166.231; 24.O.166.236; 24.O.166.237; 24.O.166.238; 24.O.166.239; 24.O.166.154; 24.O.166.157; 24.O.166.166; 24.O.166.169; 24.O.166.172; 24.O.166.175; 24.O.166.240; 24.O.166.244; 24.O.169.228; 24.O.169.229; 24.O.169.230; 24.O.169.231; 24.O.169.236; 24.O.169.237; 24.O.169.238; 24.O.169.239; 24.O.169.154; 24.O.169.157; 24.O.169.166; 24.O.169.169; 24.O.169.172; 24.O.169.175; 24.O.169.240; 24.O.169.244; 24.O.172.228; 24.O.172.229; 24.O.172.230; 24.O.172.231; 24.O.172.236; 24.O.172.237; 24.O.172.238; 24.O.172.239; 24.O.172.154; 24.O.172.157; 24.O.172.166; 24.O.172.169; 24.O.172.172; 24.O.172.175; 24.O.172.240; 24.O.172.244; 24.O.175.228; 24.O.175.229; 24.O.175.230; 24.O.175.231; 24.O.175.236; 24.O.175.237; 24.O.175.238; 24.O.175.239; 24.O.175.154; 24.O.175.157; 24.O.175.166; 24.O.175.169; 24.O.175.172; 24.O.175.175; 24.O.175.240; 24.O.175.244; 24.O.240.228; 24.O.240.229; 24.O.240-230; 24.O.240.231; 24.O.240.236; 24.O.240.237; 24.O.240.238; 24.O.24Q.239; 24.O.240.154; 24.O.240.157; 24.O.240.166; 24.O.240.169; 24.O.240.172; 24.O.240.175; 24.O.240.240; 24.O.240.244; 24.O.244.228; 24.O.244.229; 24.O.244.230; 24.O.244.231; 24.O.244.236; 24.O.244.237; 24.O.244.238; 24.O.244.239; 24.O.244.154; 24.O.244.157; 24.O.244.166; 24.O.244.169; 24.O.244.172; 24.O.244.175; 24.O.244.240; 24.O.244.244;

Prodrugs of 24.P

24.P.228.228; 24.P.228.229; 24.P.228.230; 24.P.228.231; 24.P.228.236; 24.P.228.237; 24.P.228.238; 24.P.228.239; 24.P.228.154; 24.P.228.157; 24.P.228.166; 24.P.228.169; 24.P.228.172; 24.P.228.175; 24.P.228.240; 24.P.228.244; 24.P.229.228; 24.P.229.229; 24.P.229.230; 24.P.229.231; 24.P.229.236; 24.P.229.237; 24.P.229.238; 24.P.229.239; 24.P.229.154; 24.P.229.157; 24.P.229.166; 24.P.229.169; 24.P.229.172; 24.P.229.175; 24.P.229.240; 24.P.229.244; 24.P.230.228; 24.P.230.229; 24.P.230.230; 24.P.230.231; 24.P.230.236; 24.P.230.237; 24.P.230.238; 24.P.230.239; 24.P.230.154; 24.P.230.157; 24.P.230.166; 24.P.230.169; 24.P.230.172; 24.P.230.175; 24.P.230.240; 24.P.230.244; 24.P.231.228; 24.P.231.229; 24.P.231.230; 24.P.231.231; 24.P.231.236; 24.P.231.237; 24.P.231.238; 24.P.231.239; 24.P.231.154; 24.P.231.157; 24.P.231.166; 24.P.231.169; 24.P.231.172; 24.P.231.175; 24.P.231.240; 24.P.231.244; 24.P.236.228; 24.P.236.229; 24.P.236.230; 24.P.236.231; 24.P.236.236; 24.P.236.237; 24.P.236.238; 24.P.236.239; 24.P.236.154; 24.P.236.157; 24.P.236.166; 24.P.236.169; 24.P.236.172; 24.P.236.175; 24.P.236.240; 24.P.236.244; 24.P.237.228; 24.P.237.229; 24.P.237.230; 24.P.237.231; 24.P.237.236; 24.P.237.237; 24.P.237.238; 24.P.237.239; 24.P.237.154; 24.P.237.157; 24.P.237.166; 24.P.237.169; 24.P.237.172; 24.P.237.175; 24.P.237.240; 24.P.237.244; 24.P.238.228; 24.P.238.229; 24.P.238.230; 24.P.238.231; 24.P.238.236; 24.P.238.237; 24.P.238.238; 24.P.238.239; 24.P.238.154; 24.P.238.157; 24.P.238.166; 24.P.238.169; 24.P.238.172; 24.P.238.175; 24.P.238.240; 24.P.238.244; 24.P.239.228; 24.P.239.229; 24.P.239.230; 24.P.239.231; 24.P.239.236; 24.P.239.237; 24.P.239.238; 24.P.239.239; 24.P.239.154; 24.P.239.157; 24.P.239.166; 24.P.239.169; 24.P.239.172; 24.P.239.175; 24.P.239.240; 24.P.239.244; 24.P.154.228; 24.P.154.229; 24.P.154.230; 24.P.154.231; 24.P.154.236; 24.P.154.237; 24.P.154.238; 24.P.154.239; 24.P.154.154; 24.P.154.157; 24.P.154.166; 24.P.154.169; 24.P.154.172; 24.P.154.175; 24.P.154.240; 24.P.154.244; 24.P.157.228; 24.P.157.229; 24.P.157.230; 24.P.157.231; 24.P.157.236; 24.P.157.237; 24.P.157.238; 24.P.157.239; 24.P.157.154; 24.P.157.157; 24.P.157.166; 24.P.157.169; 24.P.157.172; 24.P.157.175; 24.P.157.240; 24.P.157.244; 24.P.166.228; 24.P.166.229; 24.P.166.230; 24.P.166.231; 24.P.166.236; 24.P.166.237; 24.P.166.238; 24.P.166.239; 24.P.166.154; 24.P.166.157; 24.P.166.166; 24.P.166.169; 24.P.166.172; 24.P.166.175; 24.P.166.240; 24.P.166.244; 24.P.169.228; 24.P.169.229; 24.P.169.230; 24.P.169.231; 24.P.169.236; 24.P.169.237; 24.P.169.238; 24.P.169.239; 24.P.169.154; 24.P.169.157; 24.P.169.166; 24.P.169.169; 24.P.169.172; 24.P.169.175; 24.P.169.240; 24.P.169.244; 24.P.172.228; 24.P.172.229; 24.P.172.230; 24.P.172.231; 24.P.172.236; 24.P.172.237; 24.P.172.238; 24.P.172.239; 24.P.172.154; 24.P.172.157; 24.P.172.166; 24.P.172.169; 24.P.172.172; 24.P.172.175; 24.P.172.240; 24.P.172.244; 24.P.175.228; 24.P.175.229; 24.P.175.230; 24.P.175.231; 24.P.175.236; 24.P.175.237; 24.P.175.238; 24.P.175.239; 24.P.175.154; 24.P.175.157; 24.P.175.166; 24.P.175.169; 24.P.175.172; 24.P.175.175; 24.P.175.240; 24.P.175.244; 24.P.240.228; 24.P.240.229; 24.P.240.230; 24.P.240.231; 24.P.240.236; 24.P.240.237; 24.P.240.238; 24.P.240.239; 24.P.240.154; 24.P.240.157; 24.P.240.166; 24.P.240.169; 24.P.240.172; 24.P.240.175; 24.P.240.240; 24.P.240.244; 24.P.244.228; 24.P.244.229; 24.P.244.230; 24.P.244.231; 24.P.244.236; 24.P.244.237; 24.P.244.238; 24.P.244.239; 24.P.244.154; 24.P.244.157; 24.P.244.166; 24.P.244.169; 24.P.244.172; 24.P.244.175; 24.P.244.240; 24.P.244.244;

Prodrugs of 24.U

24.U.228.228; 24.U.228.229; 24.U.228.230; 24.U.228.231; 24.U.228.236; 24.U.228.237; 24.U.228.238; 24.U.228.239; 24.U.228.154; 24.U.228.157; 24.U.228.166; 24.U.228.169; 24.U.228.172; 24.U.228.175; 24.U.228.240; 24.U.228.244; 24.U.229.228; 24.U.229.229; 24.U.229.230; 24.U.229.231; 24.U.229.236; 24.U.229.237; 24.U.229.238; 24.U.229.239; 24.U.229.154; 24.U.229.157; 24.U.229.166; 24.U.229.169; 24.U.229.172; 24.U.229.175; 24.U.229.240; 24.U.229.244; 24.U.23Q.228; 24.U.230.229; 24.U.230.230; 24.U.230.231; 24.U.230.236; 24.U.230.237; 24.U.230.238; 24.U.230.239; 24.U.230.154; 24.U.230.157; 24.U.230.166; 24.U.230.169; 24.U.230.172; 24.U.230.175; 24.U.230.240; 24.U.230.244; 24.U.231.228; 24.U.231.229; 24.U.231.230; 24.U.231.231; 24.U.231.236; 24.U.231.237; 24.U.231.238; 24.U.231.239; 24.U.231.154; 24.U.231.157; 24.U.231.166; 24.U.231.169; 24.U.231.172; 24.U.231.175; 24.U.231.240; 24.U.231.244; 24.U.236.228; 24.U.236.229; 24.U.236.230; 24.U.236.231; 24.U.236.236; 24.U.236.237; 24.U.236.238; 24.U.236.239; 24.U.236.154; 24.U.236.157; 24.U.236.166; 24.U.236.169; 24.U.236.172; 24.U.236.175; 24.U.236.240; 24.U.236.244; 24.U.237.228; 24.U.237.229; 24.U.237.230; 24.U.237.231; 24.U.237.236; 24.U.237.237; 24.U.237.238; 24.U.237.239; 24.U.237.154; 24.U.237.157; 24.U.237.166; 24.U.237.169; 24.U.237.172; 24.U.237.175; 24.U.237.240; 24.U.237.244; 24.U.238.228; 24.U.238.229; 24.U.238.230; 24.U.238.231; 24.U.238.236; 24.U.238.237; 24.U.238.238; 24.U.238.239; 24.U.238.154; 24.U.238.157; 24.U.238.166; 24.U.238.169; 24.U.238.172; 24.U.238.175; 24.U.238.240; 24.U.238.244; 24.U.239.228; 24.U.239.229; 24.U.239.230; 24.U.239.231; 24.U.239.236; 24.U.239.237; 24.U.239.238; 24.U.239.239; 24.U.239.154; 24.U.239.157; 24.U.239.166; 24.U.239.169; 24.U.239.172; 24.U.239.175; 24.U.239.240; 24.U.239.244; 24.U.154.228; 24.U.154.229; 24.U.154.230; 24.U.154.231; 24.U.154.236; 24.U.154.237; 24.U.154.238; 24.U.154.239; 24.U.154.154; 24.U.154.157; 24.U.154.166; 24.U.154.169; 24.U.154.172; 24.U.154.175; 24.U.154.240; 24.U.154.244; 24.U.157.228; 24.U.157.229; 24.U.157.230; 24.U.157.231; 24.U.157.236; 24.U.157.237; 24.U.157.238; 24.U.157.239; 24.U.157.154; 24.U.157.157; 24.U.157.166; 24.U.157.169; 24.U.157.172; 24.U.157.175; 24.U.157.24Q; 24.U.157.244; 24.U.166.228; 24.U.166.229; 24.U.166.230; 24.U.166.231; 24.U.166.236; 24.U.166.237; 24.U.166.238; 24.U.166.239; 24.U.166.154; 24.U.166.157; 24.U.166.166; 24.U.166.169; 24.U.166.172; 24.U.166.175; 24.U.166.240; 24.U.166.244; 24.U.169.228; 24.U.169.229; 24.U.169.230; 24.U.169.231; 24.U.169.236; 24.U.169.237; 24.IJ.169.238; 24.U.169.239; 24.U.169.154; 24.U.169.157; 24.U.169.166; 24.U.169.169; 24.U.169.172; 24.U.169.175; 24.U.169.240; 24.U.169.244; 24.U.172.228; 24.U.172.229; 24.U.172.230; 24.U.172.231; 24.U.172.236; 24.U.172.237; 24.U.172.238; 24.U.172.239; 24.U.172.154; 24.U.172.157; 24.U.172.166; 24.U.172.169; 24.U.172.172; 24.U.172.175; 24.U.172.240; 24.U.172.244; 24.U.175.228; 24.U.175.229; 24.U.175.230; 24.U.175.231; 24.U.175.236; 24.U.175.237; 24.U.175.238; 24.U.175.239; 24.U.175.154; 24.U.175.157; 24.U.175.166; 24.U.175.169; 24.U.175.172; 24.U.175.175; 24.U.175.24Q; 24.U.175.244; 24.U.240.228; 24.U.240.229; 24.U.240.230; 24.U.240.231; 24.U.240.236; 24.U.240.237; 24.U.240.238; 24.U.240.239; 24.U.240.154; 24.U.240.157; 24.U.240.166; 24.U.240.169; 24.U.240.172; 24.U.240.175; 24.U.240.240; 24.U.240.244; 24.U.244.228; 24.U.244.229; 24.U.244.230; 24.U.244.231; 24.U.244.236; 24.U.244.237; 24.U.244.238; 24.U.244.239; 24.U.244.154; 24.U.244.157; 24.U.244.166; 24.U-244.169; 24.U.244.172; 24.U.244.175; 24.U.244.240; 24.U.244.244;

Prodrugs of 24.CD

24.CP.228.228; 24.CD.228.229; 24.CD.228.230; 24.CD.228.231; 24.CD.228.236; 24.CD.228.237; 24.CD.228.238; 24.CD.228-239; 24.CD.228.154; 24.CD.228.157; 24.CD.228.166; 24.CD.228.169; 24.CD.228.172; 24.CP.228.175; 24.CD.228.240; 24.CD.228.244; 24.CD.229.228; 24.CD.229.229; 24.CD.229.230; 24.CD.229.231; 24.CD.229.236; 24.CD.229.237; 24.CD.229.238; 24.CD.229.239; 24.CD.229.154; 24.CD.229.157; 24.CD.229.166; 24.CD.229.169; 24.CP.229.172; 24.CP.229.175; 24.CP.229.240; 24.CP.229.244; 24.CP.230.228; 24.CP.230.229; 24.CP.230.230; 24.CP.230.231; 24.CP.230.236; 24.CP.230.237; 24.CP.230.238; 24.CP.230.239; 24.CP.230.154; 24.CP.230.157; 24.CP.230.166; 24.CP.230.169; 24.CP.230.172; 24.CP.230.175; 24.CP.230.240; 24.CP.230.244; 24.CP.231.228; 24.CP.231.229; 24.CP.231.230; 24.CP.231.231; 24.CP.231.236; 24.CP.231.237; 24.CP.231.238; 24.CP.231.239; 24.CP.231.154; 24.CP.231.157; 24.CP.231.166; 24.CP.231.169; 24.CP.231.172; 24.CP.231.175; 24.CP.231.240; 24.CP.231.244; 24.CP.236.228; 24.CP.236.229; 24.CP.236.230; 24.CP.236.231; 24.CP.236.236; 24.CP.236.237; 24.CP.236.238; 24.CP.236.239; 24.CP.236.154; 24.CP.236.157; 24.CP.236.166; 24.CP.236.169; 24.CP.236.172; 24.CP.236.175; 24.CP.236.240; 24.CP.236.244; 24.CP.237.228; 24.CP.237.229; 24.CP.237.230; 24.CP.237.231; 24.CP.237.236; 24.CP.237.237; 24.CP.237.238; 24.CP.237.239; 24.CP.237.154; 24.CP.237.157; 24.CP.237.166; 24.CP.237.169; 24.CP.237.172; 24.CP.237.175; 24.CP.237.240; 24.CP.237.244; 24.CP.238.228; 24.CP.238.229; 24.CP.238.230; 24.CP.238.231; 24.CP.238.236; 24.CP.238.237; 24.CP.238.238; 24.CP.238.239; 24.CP.238.154; 24.CP.238.157; 24.CP.238.166; 24.CP.238.169; 24.CP.238.172; 24.CP.238.175; 24.CD.238.240; 24.CD.238.244; 24.CD.239.228; 24.CD.239.229; 24.CD.239.230; 24.CD.239.231; 24.CD.239.236; 24.CD.239.237; 24.CD.239.238; 24.CD.239.239; 24.CD.239.154; 24.CD.239.157; 24.CD.239.166; 24.CD.239.169; 24.CD.239.172; 24.CD.239.175; 24.CD.239.240; 24.CD.239.244; 24.CD.154.228; 24.CD.154.229; 24.CD.154.230; 24.CD.154.231; 24.CD.154.236; 24.CD.154.237; 24.CD.154.238; 24.CD.154.239; 24.CD.154.154; 24.CD.154.157; 24.CD.154.166; 24.CD.154.169; 24.CD.154.172; 24.CD.154.175; 24.CD.154.240; 24.CD.154.244; 24.CD.157.228; 24.CD.157.229; 24.CD.157.230; 24.CD.157.231; 24.CD.157.236; 24.CD.157.237; 24.CD.157.238; 24.CD.157.239; 24.CD.157.154; 24.CD.157.157; 24.CD.157.166; 24.CD.157.169; 24.CD.157.172; 24.CD.157.175; 24.CD.157.240; 24.CD.157.244; 24.CD.166.228; 24.CD.166.229; 24.CD.166.230; 24.CD.166.231; 24.CD.166.236; 24.CD.166.237; 24.CD.166.238; 24.CD.166.239; 24.CD.166.154; 24.CD.166.157; 24.CD.166.166; 24.CD.166.169; 24.CD.166.172; 24.CD.166.175; 24.CD.166.240; 24.CD.166.244; 24.CD.169.228; 24.CD.169.229; 24.CD.169.230; 24.CD.169.231; 24.CD.169.236; 24.CD.169.237; 24.CD.169.238; 24.CD.169.239; 24.CD.169.154; 24.CD.169.157; 24.CD.169.166; 24.CD.169.169; 24.CD.169.172; 24.CD.169.175; 24.CD.169.240; 24.CD.169.244; 24.CD.172.228; 24.CD.172.229; 24.CD.172.230; 24.CD.172.231; 24.CD.172.236; 24.CD.172.237; 24.CD.172.238; 24.CD.172.239; 24.CD.172.154; 24.CD.172.157; 24.CD.172.166; 24.CD.172.169; 24.CD.172.172; 24.CD.172.175; 24.CD.172.240; 24.CD.172.244; 24.CD.175.228; 24.CD.175.229; 24.CD.175.230; 24.CD.175.231; 24.CD.175.236; 24.CD.175.237; 24.CD.175.238; 24.CD.175.239; 24.CD.175.154; 24.CD.175.157; 24.CD.175.166; 24.CD.175.169; 24.CD.175.172; 24.CD.175.175; 24.CD.175.240; 24.CD.175.244; 24.CD.240.228; 24.CD.240.229; 24.CD.240.230; 24.CD.240.231; 24.CD.240.236; 24.CD.240.237; 24.CD.24Q.238; 24.CD.240.239; 24.CD.240.154; 24.CD.240.157; 24.CD.240.166; 24.CD.240.169; 24.CD.240.172; 24.CD.240.175; 24.CD.24Q.240; 24.CD.240.244; 24.CD.244.228; 24.CD.244.229; 24.CD.244.230; 24.CD.244.231; 24.CD.244.236; 24.CD.244.237; 24.CD.244.238; 24.CD.244.239; 24.CD.244.154; 24.CD.244.157; 24.CD.244.166; 24.CD.244.169; 24.CD.244.172; 24.CD.244.175; 24.CD.244.240; 24.CD.244.244;

Prodrugs of 24.EB

24.EB.228.228; 24.EB.228.229; 24.EB.228.230; 24.EB.228.231; 24.EB.228.236; 24.EB.228.237; 24.EB.228.238; 24.EB.228.239; 24.EB.228.154; 24.EB.228.157; 24.EB.228.166; 24.EB.228.169; 24.EB.228.172; 24.EB.228.175; 24.EB.228.240; 24.EB.228.244; 24.EB.229.228; 24.EB.229.229; 24.EB.229.230; 24.EB.229.231; 24.EB.229.236; 24.EB.229.237; 24.EB.229.238; 24.EB.229.239; 24.EB.229.154; 24.EB.229.157; 24.EB.229.166; 24.EB.229.169; 24.EB.229.172; 24. EB .229.175; 24.EB.229.240; 24.EB.229.244; 24.EB.230.228; 24.EB.23Q.229; 24.EB.230.230; 24.EB.230.231; 24.EB.230.236; 24.EB.230.237; 24.EB.230.238; 24.EB.230.239; 24.EB.230.154; 24.EB.230.157; 24.EB.230.166; 24.EB.230.169; 24.EB.230.172; 24.EB.230.175; 24.EB.230.240; 24.EB.230.244; 24.EB.231.228; 24.EB.231.229; 24.EB.231.230; 24.EB.231.231; 24.EB.231.236; 24.EB.231.237; 24.EB.231.238; 24.EB.231.239; 24.EB.231.154; 24.EB.231.157; 24.EB.231.166; 24.EB.231.169; 24.EB.231.172; 24.EB.231.175; 24.EB.231.240; 24.EB.231.244; 24.EB.236.228; 24.EB.236.229; 24.EB.236.230; 24.EB.236.231; 24.EB.236.236; 24.EB.236.237; 24.EB.236.238; 24.EB.236.239; 24.EB.236.154; 24.EB.236.157; 24.EB.236.166; 24.EB.236.169; 24.EB.236.172; 24.EB.236.175; 24.EB.236.240; 24.EB.236.244; 24.EB.237.228; 24.EB.237.229; 24.EB.237.230; 24.EB.237.231; 24.EB.237.236; 24.EB.237.237; 24.EB.237.238; 24.EB.237.239; 24.EB.237.154; 24.EB.237.157; 24.EB.237.166; 24.EB.237.169; 24.EB.237.172; 24.EB.237.175; 24.EB.237.240; 24.EB.237.244; 24.EB.238.228; 24.EB.238.229; 24.EB.238.23Q; 24.EB.238.231; 24.EB.238.236; 24.EB.238.237; 24.EB.238.238; 24.EB.238.239; 24. EB.238.154; 24.EB.238.157; 24.EB.238.166; 24.EB.238.169; 24.EB.238.172; 24.EB.238.175; 24.EB.238.240; 24.EB.238.244; 24.EB.239.228; 24.EB.239.229; 24. EB.239.230; 24.EB.239.231; 24.EB.239.236; 24.EB.239.237; 24.EB.239.238; 24.EB.239.239; 24.EB.239.154; 24.EB.239.157; 24. EB.239.166; 24.EB.239.169; 24.EB.239.172; 24.EB.239.175; 24.EB.239.240; 24.EB.239.244; 24.EB.154.228; 24.EB.154.229; 24.EB.154.230; 24.EB.154.231; 24.EB.154.236; 24.EB.154.237; 24.EB.154.238; 24.EB.154.239; 24.EB.154.154; 24.EB.154.157; 24.EB.154.166; 24.EB.154.169; 24.EB.154.172; 24.EB.154.175; 24.EB.154.240; 24.EB.154.244; 24.EB.157.228; 24.EB.157.229; 24.EB.157.230; 24.EB.157.231; 24.EB.157.236; 24.EB.157.237; 24.EB.157.238; 24.EB.157.239; 24.EB.157.154; 24.EB.157.157; 24.EB.157.166; 24.EB.157.169; 24.EB.157.172; 24.EB.157.175; 24.EB.157.240; 24.EB.157.244; 24.EB.166.228; 24.EB.166.229; 24.EB.166.230; 24.EB.166.231; 24.EB.166.236; 24.EB.166.237; 24.EB.166.238; 24.EB.166.239; 24.EB.166.154; 24.EB.166.157; 24.EB.166.166; 24.EB.166.169; 24.EB.166.172; 24.EB.166.175; 24.EB.166.240; 24.EB.166.244; 24.EB.169.228; 24.EB.169.229; 24.EB.169.230; 24.EB.169.231; 24.EB.169.236; 24.EB.169.237; 24.EB.169.238; 24.EB.169.239; 24.EB.169.154; 24.EB.169.157; 24.EB.169.166; 24.EB.169.169; 24.EB.169.172; 24.EB.169.175; 24.EB.169.240; 24.EB.169.244; 24.EB.172.228; 24.EB.172.229; 24.EB.172.230; 24.EB.172.231; 24.EB.172.236; 24.EB.172.237; 24.EB.172.238; 24.EB.172.239; 24.EB.172.154; 24.EB.172.157; 24.EB.172.166; 24.EB.172.169; 24.EB.172.172; 24.EB.172.175; 24.EB.172.240; 24.EB.172.244; 24.EB.175.228; 24.EB.175.229; 24.EB.175.23Q; 24.EB.175.231; 24.EB.175.236; 24.EB.175.237; 24.EB.175.238; 24.EB.175.239; 24.EB.175.154; 24.EB.175.157; 24.EB.175.166; 24.EB.175.169; 24.EB.175.172; 24.EB.175.175; 24.EB.175.240; 24.EB.175.244; 24.EB.240.228; 24.EB.240.229; 24.EB.240.230; 24.EB.240.231; 24.EB.240.236; 24.EB.240.237; 24.EB.240.238; 24.EB.240.239; 24.EB.240.154; 24.EB.240.157; 24.EB.240-166; 24.EB.240.169; 24.EB.240.172; 24.EB.240.175; 24.EB.240.240; 24.EB.240.244; 24.EB.244.228; 24.EB.244.229; 24.EB.244.230; 24.EB.244.231; 24.EB.244.236; 24.EB.244.237; 24.EB.244.238; 24.EB.244.239; 24.EB.244.154; 24.EB.244.157; 24.EB.244.166; 24. EB.244.169; 24.EB.244.172; 24.EB.244.175; 24.EB.244.240; 24.EB.244.244.

[0200] This application specifically excludes compounds disclosed in WO 2005/042556 and WO 2005/044835. General Synthetic Methods

[0201] The compounds of the embodiments can be prepared from readily available starting materials using the following general methods and procedures. [0202] Many such techniques are well known in the art, such as those elaborated in "Compendium of Organic Synthetic Methods" (John Wiley & Sons, New York), Vol. 1, Ian T. Harrison and Shuyen Harrison, 1971; Vol. 2, Ian T. Harrison and Shuyen Harrison, 1974; Vol. 3, Louis S. Hegedus and Leroy Wade, 1977; Vol. 4, Leroy G. Wade, jr., 1980; Vol. 5, Leroy G. Wade, Jr., 1984; and Vol. 6, Michael B. Smith; as well as March, J., "Advanced Organic Chemistry, Third Edition", (John Wiley & Sons, New York, 1985), "Comprehensive Organic Synthesis. Selectivity, Strategy & Efficiency in Modern Organic Chemistry. In 9 Volumes", Barry M. Trost, Editor-in-Chief (Pergamon Press, New York, 1993 printing). It will be appreciated that where typical or preferred process conditions (i.e., reaction temperatures, times, mole ratios of reactants, solvents, pressures, etc.) are given, other process conditions can also be used unless otherwise stated. Optimum reaction conditions may vary with the particular reactants or solvent used, but such conditions can be determined by one skilled in the art by routine optimization procedures.

[0203] Additionally, as will be apparent to those skilled in the art, conventional protecting groups may be necessary to prevent certain functional groups from undergoing undesired reactions. Suitable protecting groups for various functional groups as well as suitable conditions for protecting and deprotecting particular functional groups are well known in the art. For example, numerous protecting groups are described in T. W. Greene and G. M. Wuts, Protecting Groups in Organic Synthesis, Third Edition, Wiley, New York, 1999, and references cited therein.

[0204] Furthermore, the compounds of the embodiments contain one or more chiral centers. Accordingly, if desired, such compounds can be prepared or isolated as pure stereoisomers, i.e., as individual enantiomers or diastereomers, or as stereoisomer-enriched mixtures. AU such stereoisomers (and enriched mixtures) are included within the scope of the embodiments, unless otherwise indicated. Pure stereoisomers (or enriched mixtures) may be prepared using, for example, optically active starting materials or stereoselective reagents well- known in the art. Alternatively, racemic mixtures of such compounds can be separated using, for example, chiral column chromatography, chiral resolving agents and the like.

[0205] The starting materials for the following reactions are generally known compounds or can be prepared by known procedures or obvious modifications thereof. For example, many of the starting materials are available from commercial suppliers such as Aldrich Chemical Co. (Milwaukee, Wisconsin, USA), Bachem (Torrance, California, USA), Emka-Chemce or Sigma (St. Louis, Missouri, USA). Others may be prepared by procedures, or obvious modifications thereof, described in standard reference texts such as Fieser and Fieser's Reagents for Organic Synthesis, Volumes 1-15 (John Wiley and Sons, 1991), Rodd's Chemistry of Carbon Compounds, Volumes 1-5 and Supplemental (Elsevier Science Publishers, 1989), Organic Reactions, Volumes 1-40 (John Wiley and Sons, 1991), March's Advanced Organic Chemistry, (John Wiley and Sons, 4* Edition), and Larock's Comprehensive Organic Transformations (VCH Publishers Inc., 1989). Specifically, the compounds of the embodiments may be prepared by various methods known in the art of organic chemistry in general and nucleoside and nucleotide analogue synthesis in particular. General reviews of the preparation of nucleoside and nucleotide analogues include 1) Michelson A.M. "The Chemistry of Nucleosides and Nucleotides," Academic Press, New York, 1963; 2) Goodman L. "Basic Principles in Nucleic Acid Chemistry " Academic Press, New York, 1974, vol. 1, Ch. 2; and 3) "Synthetic Procedures in Nucleic Acid Chemistry," Eds. Zorbach W. & Tipson R., Wiley, New York, 1973, vol. 1 & 2.

[0206] In each of the exemplary Schemes herein, it may be advantageous to separate reaction products from one another and/or from starting materials. The desired products of each step or series of steps is separated and/or purified (hereinafter separated) to the desired degree of homogeneity by the techniques common in the art. Typically such separations involve multiphase extraction, crystallization from a solvent or solvent mixture, distillation, sublimation, or chromatography. Chromatography can involve any number of methods including, for example, size exclusion or ion exchange chromatography, high, medium, or low pressure liquid chromatography, small scale and preparative thin or thick layer chromatography, as well as techniques of small scale thin layer and flash chromatography.

[0207] Another class of separation methods involves treatment of a mixture with a reagent selected to bind to or render otherwise separable a desired product, unreacted starting material, reaction by product, or the like. Such reagents include adsorbents or absorbents such as activated carbon, molecular sieves, ion exchange media, or the like. Alternatively, the reagents can be acids in the case of a basic material, bases in the case of an acidic material, binding reagents such as antibodies, binding proteins, selective chelators such as crown ethers, liquid/liquid ion extraction reagents (LIX), or the like.

[0208] Selection of appropriate methods of separation depends on the nature of the materials involved. For example, boiling point, and molecular weight in distillation and sublimation, presence or absence of polar functional groups in chromatography, stability of materials in acidic and basic media in multiphase extraction, and the like. One skilled in the art will apply techniques most likely to achieve the desired separation.

[0209] All literature and patent citations above are hereby expressly incorporated by reference at the locations of their citation. Specifically cited sections or pages of the above cited works are incorporated by reference with specificity. The invention has been described in detail sufficient to allow one of ordinary skill in the art to make and use the subject matter of the following Embodiments. It is apparent that certain modifications of the methods and compositions of the following Embodiments can be made within the scope and spirit of the invention.

[0210] Dialkyl phosphonates may be prepared according to the methods of: Quast et al (1974) Synthesis 490; Stowell et al (1990) Tetrahedron Lett. 3261; US Patent No. 5,663,159, all of which are herein incorporated by reference in their entirety.

[0211] In general, synthesis of phosphonate esters is achieved by coupling a nucleophile amine or alcohol with the corresponding activated phosphonate electrophilic precursor. For example, chlorophosphonate addition on to 5'- hydroxy of nucleoside is a well known method for preparation of nucleoside phosphate monoesters. The activated precursor can be prepared by several well known methods. Chlorophosphonates useful for synthesis of the prodrugs are prepared from the substituted- 1,3 -propanediol (Wissner, et al, (1992) J Med Chem. 35:1650, herein incorporated by reference in its entirety). Chlorophosphonates are made by oxidation of the corresponding chlorophospholanes (Anderson, et al, (1984) J Org. Chem. 49:1304, herein incorporated by reference in its entirety) which are obtained by reaction of the substituted diol with phosphorus trichloride. Alternatively, the chlorophosphonate agent is made by treating substituted-l,3-diols with phosphorusoxychloride (Patois, et al, (1990) J Chem. Soc. Perkin Trans. I, 1577, herein incorporated by reference in its entirety). Chlorophosphonate species may also be generated in situ from corresponding cyclic phosphites (Silverburg, et al., (1996) Tetrahedron Lett., 31:111-11 '4, herein incorporated by reference in its entirety), which in turn can be either made from chlorophospholane or phosphoramidate intermediate. Phosphoroflouridate intermediate prepared either from pyrophosphate or phosphoric acid may also act as precursor in preparation of cyclic prodrugs (Watanabe et al., (1988) Tetrahedron Lett., 29:5763-66, herein incorporated by reference in its entirety). Caution: fluorophosphonate compounds may be highly toxic!

[0212] Phosphonate prodrugs of the present embodiments may also be prepared from the precursor free acid by Mitsunobu reactions (Mitsunobu, (1981) Synthesis, 1; Campbell, (1992) J. Org. Chem., 52:6331, herein incorporated by reference in its entirety), and other acid coupling reagents including, but not limited to, carbodiimides (Alexander, et al, (1994) Collect. Czech. Chem. Commun. 59:1853; Casara, et al, (1992) Bioorg. Med. Chem. Lett., 2:145; Ohashi, et al, (1988) Tetrahedron Lett., 29:1189, all of which are herein incorporated by reference in their entirety), and benzotriazolyloxytris- (dimethylamino)phosphonium salts (Campagne, et al, (1993) Tetrahedron Lett., 34:6743, herein incorporated by reference in its entirety). [0213] Aryl halides undergo Ni⁺² catalyzed reaction with phosphite derivatives to give aryl phosphonate containing compounds (Balthazar, et al (1980) J Org. Chem. 45:5425, herein incorporated by reference in its entirety). Phosphonates may also be prepared from the chlorophosphonate in the presence of a palladium catalyst using aromatic triflates (Petrakis, et al, (1987) J. Am. Chem. 5Oc.109:2831; Lu, et al, (1987) Synthesis, 726, all of which are herein incorporated by reference in their entirety). In another method, aryl phosphonate esters are prepared from aryl phosphates under anionic rearrangement conditions (Melvin (1981) Tetrahedron Lett. 22:3375; Casteel, et al, (1991) Synthesis, 691, herein incorporated by reference in its entirety). N-Alkoxy aryl salts with alkali metal derivatives of cyclic alkyl phosphonate provide general synthesis for heteroaryl-2-phosphonate linkers (Redmore (197O) J. Org. Chem. 35:4114, herein incorporated by reference in its entirety). These above mentioned methods can also be extended to compounds where the W⁵ group is a heterocycle. Cyclic- 1,3-propanyl prodrugs of phosphonates are also synthesized from phosphonic diacids and substituted propane- 1, 3 -diols using a coupling reagent such as 1,3- dicyclohexylcarbodiimide (DCC) in presence of a base (e.g., pyridine). Other carbodiimide based coupling agents like 1,3-disopropylcarbodiimide or water soluble reagent, l-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDCI) can also be utilized for the synthesis of cyclic phosphonate prodrugs. [0214] The carbamoyl group may be formed by reaction of a hydroxy group according to the methods known in the art, including the teachings of Ellis, US 2002/0103378 Al and Hajima, US Patent No. 6,018,049, all of which are herein incorporated by reference in their entirety.

[0215] Additional detailed descriptions for preparing the phosphate prodrugs of the present embodiments can be found in Arimilli, et al. International Patent Application WO 03/090690, which is incorporated herein by reference in its entirety.

Scheme 1001

[0216] Scheme 1001 shows the interconversions of certain phosphonate compounds: acids -P(O)(OH)₂; mono-esters -P(O)(OR^sl)(OH); and diesters - P(O)(OR^sl)₂ in which the R^sl groups are independently selected, and defined herein before, and the phosphorus is attached through a carbon moiety (link, i.e. linker), which is attached to the rest of the molecule, e.g. drug or drug intermediate (R). The R^sl groups attached to the phosphonate esters in Scheme 1001 may be changed using established chemical transformations. The interconversions may be carried out in the precursor compounds or the final products using the methods described below. The methods employed for a given phosphonate transformation depend on the nature of the substituent R^sl. The preparation and hydrolysis of phosphonate esters is described in Organic Phosphorus Compounds, G. M. Kosolapoff, L. Maeir, eds, Wiley, 1976, p. 9ff. [0217] The conversion of a phosphonate diester 27.1 into the corresponding phosphonate monoester 27.2 (Scheme 1001, Reaction 1) can be accomplished by a number of methods. For example, the ester 27.1 in which R^sl is an arylalkyl group such as benzyl, can be converted into the monoester compound 27.2 by reaction with a tertiary organic base such as diazabicyclooctane (DABCO) or quinuclidine, as described in J Org. Chem., 1995, 60:2946. The reaction is performed in an inert hydrocarbon solvent such as toluene or xylene, at about 110°C The conversion of the diester 27.1 in which R¹ is an aryl group such as phenyl, or an alkenyl group such as allyl, into the monoester 27.2 can be effected by treatment of the ester 27.1 with a base such as aqueous sodium hydroxide in acetonitrile or lithium hydroxide in aqueous tetrahydrofuran. Phosphonate diesters 27.2 in which one of the groups R^sl is arylalkyl, such as benzyl, and the other is alkyl, can be converted into the monoesters 27.2 in which R^sl is alkyl, by hydrogenation, for example using a palladium on carbon catalyst. Phosphonate diesters in which both of the groups R^sl are alkenyl, such as allyl, can be converted into the monoester 27.2 in which R^sl is alkenyl, by treatment with chlorotris(triphenylphosphine)rhodium (Wilkinson's catalyst) in aqueous ethanol at reflux, optionally in the presence of diazabicyclooctane, for example by using the procedure described in J Org. Chem., 38:3224 1973 for the cleavage of allyl carboxylates.

[0218] The conversion of a phosphonate diester 27.1 or a phosphonate monoester 27.2 into the corresponding phosphonic acid 27.3 (Scheme 1001, Reactions 2 and 3) can be effected by reaction of the diester or the monoester with trimethylsilyl bromide, as described in J Chem. Soc, Chem. Comm., 739, 1979. The reaction is conducted in an inert solvent such as, for example, dichloromethane, optionally in the presence of a silylating agent such as bis(trimethylsilyl)trifluoroacetamide, at ambient temperature. A phosphonate monoester 27.2 in which R^sl is arylalkyl such as benzyl, can be converted into the corresponding phosphonic acid 27.3 by hydrogenation over a palladium catalyst, or by treatment with hydrogen chloride in an ethereal solvent such as dioxane. A phosphonate monoester 27.2 in which R^sl is alkenyl such as, for example, allyl, can be converted into the phosphonic acid 27.3 by reaction with Wilkinson's catalyst in an aqueous organic solvent, for example in 15% aqueous acetonitrile, or in aqueous ethanol, for example using the procedure described in HeIv. Chim. Acta., 68:618, 1985. Palladium catalyzed hydrogenolysis of phosphonate esters 27.1 in which R^sl is benzyl is described in J Org. Chem., 24:434, 1959. Platinum-catalyzed hydrogenolysis of phosphonate esters 27.1 in which R^sl is phenyl is described in J Amer. Chem. Soc, 78:2336, 1956. [0219] The conversion of a phosphonate monoester 27.2 into a phosphonate diester 27.1 (Scheme 1001, Reaction 4) in which the newly introduced R^sl group is alkyl, arylalkyl, or haloalkyl such as chloroethyl, can be effected by a number of reactions in which the substrate 27.2 is reacted with a hydroxy compound R^s OH, in the presence of a coupling agent. Suitable coupling agents are those employed for the preparation of carboxylate esters, and include a carbodiimide such as dicyclohexylcarbodiimide, in which case the reaction is preferably conducted in a basic organic solvent such as pyridine, or (benzotriazol-1- yloxy)tripyrrolidinophosphonium hexafluorophosphate (PYBOP, Sigma), in which case the reaction is performed in a polar solvent such as dimethylformamide, in the presence of a tertiary organic base such as diisopropylethylamine, or Aldrithiol-2 (Aldrich) in which case the reaction is conducted in a basic solvent such as pyridine, in the presence of a triaryl phosphine such as triphenylphosphine. Alternatively, the conversion of the phosphonate monoester 27.1 to the diester 27.1 can be effected by the use of the Mitsunobu reaction. The substrate is reacted with the hydroxy compound R¹OH, in the presence of diethyl azodicarboxylate and a triarylphosphine such as triphenyl phosphine. Alternatively, the phosphonate monoester 27.2 can be transformed into the phosphonate diester 27.1, in which the introduced R^sl group is alkenyl or arylalkyl, by reaction of the monoester with the halide R^slBr, in which R^sl is as alkenyl or arylalkyl. The alkylation reaction is conducted in a polar organic solvent such as dimethylformamide or acetonitrile, in the presence of a base such as cesium carbonate. Alternatively, the phosphonate monoester can be transformed into the phosphonate diester in a two step procedure. In the first step, the phosphonate monoester 27.2 is transformed into the chloro analog - P(O)(OR^sl)Cl by reaction with thionyl chloride or oxalyl chloride and the like, as described in Organic Phosphorus Compounds, G. M. Kosolapoff, L. Maeir, eds, Wiley, 1976, p. 17, and the thus-obtained product -P(O)(OR^sl)Cl is then reacted with the hydroxy compound R^slOH, in the presence of a base such as triethylamine, to afford the phosphonate diester 27.1. [0220] A phosphonic acid -P(O)(OH)₂ can be transformed into a phosphonate monoester -P(O)(OR^sl)(OH) (Scheme 1001, Reaction 5) by means of the methods described above of for the preparation of the phosphonate diester - P(O)(OR^sl)₂27.1, except that only one molar proportion of the component R^slOH or R^slBr is employed.

[0221] A phosphonic acid -P(O)(OH)₂27.3 can be transformed into a phosphonate diester -P(O)(OR^sl)₂ 27.1 (Scheme 1, Reaction 6) by a coupling reaction with the hydroxy compound R^slOH, in the presence of a coupling agent such as Aldrithiol-2 (Aldrich) and triphenylphosphine. The reaction is conducted in a basic solvent such as pyridine. Alternatively, phosphonic acids 27.3 can be transformed into phosphonic esters 27.1 in which R^sl is aryl, such as phenyl, by means of a coupling reaction employing, for example, phenol and dicyclohexylcarbodiimide in pyridine at about 7O°C. Alternatively, phosphonic acids 27.3 can be transformed into phosphonic esters 27.1 in which R^sl is alkenyl, by means of an alkylation reaction. The phosphonic acid is reacted with the alkenyl bromide R^slBr in a polar organic solvent such as acetonitrile solution at reflux temperature, in the presence of a base such as cesium carbonate, to afford the phosphonic ester 27.1..

Carboalkoxy-substituted phosphonate bisamidates, monoamidates, diesters and monoesters:

[0222] A number of methods are available for the conversion of phosphonic acids into amidates and esters. In one group of methods, the phosphonic acid is either converted into an isolated activated intermediate such as a phosphoryl chloride, or the phosphonic acid is activated in situ for reaction with an amine or a hydroxy compound.

[0223] The conversion of phosphonic acids into phosphoryl chlorides is accomplished by reaction with thionyl chloride, for example as described in J. Gen. Chem. USSR, 1983, 53, 480, Zh. Obschei Khim., 1958, 28, 1063, or J. Org. Chem., 1994, 59, 6144, or by reaction with oxalyl chloride, as described in J. Am. Chem. Soc, 1994, 116, 3251, or J. Org. Chem., 1994, 59, 6144, or by reaction with phosphorus pentachloride, as described in J. Org. Chem., 2001, 66, 329, or in J. Med. Chem., 1995, 38, 1372. The resultant phosphoryl chlorides are then reacted with amines or hydroxy compounds in the presence of a base to afford the amidate or ester products.

[0224] Phosphonic acids are converted into activated imidazolyl derivatives by reaction with carbonyl diimidazole, as described in J. Chem. Soc, Chem. Comm., 1991, 312, or Nucleosides Nucleotides 2000, 19, 1885. Activated sulfonyloxy derivatives are obtained by the reaction of phosphonic acids with trichloromethylsulfonyl chloride, as described in J. Med. Chem. 1995, 38, 4958, or with triisopropylbenzenesulfonyl chloride, as described in Tet. Lett., 1996, 7857, or Bioorg. Med. Chem. Lett., 1998, 8, 663. The activated sulfonyloxy derivatives are then reacted with amines or hydroxy compounds to afford amidates or esters.

[0225] Alternatively, the phosphonic acid and the amine or hydroxy reactant are combined in the presence of a diimide coupling agent. The preparation of phosphonic amidates and esters by means of coupling reactions in the presence of dicyclohexyl carbodiimide is described, for example, in J. Chem. Soc, Chem. Comm., 1991, 312, or J. Med. Chem., 1980, 23, 1299 or Coll. Czech. Chem. Comm., 1987, 52, 2792. The use of ethyl dimethylaminopropyl carbodiimide for activation and coupling of phosphonic acids is described in Tet. Lett., 2001, 42, 8841, or Nucleosides Nucleotides, 2000, 19, 1885.

[0226] A number of additional coupling reagents have been described for the preparation of amidates and esters from phosphonic acids. The agents include Aldrithiol-2, and PYBOP and BOP, as described in J. Org. Chem., 1995, 60, 5214, and J. Med. Chem., 1997, 40, 3842, mesitylene-2-sulfonyl-3-nitro- 1,2,4- triazole (MSNT), as described in J. Med. Chem., 1996, 39, 4958, diphenylphosphoryl azide, as described in J. Org. Chem., 1984, 49, 1158, 1- (2,4,6-triisopropylbenzenesulfonyl-3-nitro-l,2,4-triazole (TPSNT) as described in Bioorg. Med. Chem. Lett., 1998, 8, 1013, bromotris(dimethylamino)phosphonium hexafluorophosphate (BroP), as described in Tet. Lett., 1996, 37, 3997, 2-chloro-5,5-dimethyl-2-oxo- 1,3,2- dioxaphosphinane, as described in Nucleosides Nucleotides 1995, 14, 871, and diphenyl chlorophosphate, as described in J. Med. Chem., 1988, 31, 1305. [0227] Phosphonic acids are converted into amidates and esters by means of the Mitsonobu reaction, in which the phosphonic acid and the amine or hydroxy reactant are combined in the presence of a triaryl phosphine and a dialkyl azodicarboxylate. The procedure is described in Org. Lett., 2001, 3, 643, or J. Med. Chem., 1997, 40, 3842.

[0228] Phosphonic esters are also obtained by the reaction between phosphonic acids and halo compounds, in the presence of a suitable base. The method is described, for example, in Anal. Chem., 1987, 59, 1056, or J. Chem. Soc. Perkin Trans., I, 1993, 19, 2303, or J. Med. Chem., 1995, 38, 1372, or Tet. Lett., 2002, 43, 1161.

[0229] Schemes 1 - 4 illustrate the conversion of phosphonate esters and phosphonic acids into carboalkoxy-substituted phosphorobisamidates (Scheme 1), phosphoroamidates (Scheme 2), phosphonate monoesters (Scheme 3) and phosphonate diesters, (Scheme 4).

[0230] Scheme 1 illustrates various methods for the conversion of phosphonate diesters 1.1 into phosphorobisamidates 1.5. The diester 1.1, prepared as described previously, is hydrolyzed, either to the monoester 1.2 or to the phosphonic acid 1.6. The methods employed for these transformations are described above. The monoester 1.2 is converted into the monoamidate 1.3 by reaction with an aminoester 1.9, in which the group R^s2 is H or alkyl, the group R^s4 is an alkylene moiety such as, for example, CHCH₃, CHPr¹, CH(CH₂Ph), CH₂CH(CH₃) and the like, or a group present in natural or modified aminoacids, and the group R^s5 is alkyl. The reactants are combined in the presence of a coupling agent such as a carbodiimide, for example dicyclohexyl carbodiimide, as described in J. Am. Chem. Soc, 1957, 79, 3575, optionally in the presence of an activating agent such as hydroxybenztriazole, to yield the amidate product 1.3. The amidate-forming reaction is also effected in the presence of coupling agents such as BOP, as described in J. Org. Chem., 1995, 60, 5214, Aldrithiol, PYBOP and similar coupling agents used for the preparation of amides and esters. Alternatively, the reactants 1.2 and 1.9 are transformed into the monoamidate 1.3 by means of a Mitsonobu reaction. The preparation of amidates by means of the Mitsonobu reaction is described in J. Med. Chem., 1995, 38, 2742. Equimolar amounts of the reactants are combined in an inert solvent such as tetrahydrofuran in the presence of a triaryl phosphine and a dialkyl azodicarboxylate. The thus- obtained monoamidate ester 1.3 is then transformed into amidate phosphonic acid 1.4. The conditions used for the hydrolysis reaction depend on the nature of the R^sl group, as described previously. The phosphonic acid amidate 1.4 is then reacted with an aminoester 1.9, as described above, to yield the bisamidate product 1.5, in which the amino substituents are the same or different. [0231] An example of this procedure is shown in Scheme 1, Example 1. In this procedure, a dibenzyl phosphonate 1.14 is reacted with diazabicyclooctane (DABCO) in toluene at reflux, as described in J. Org. Chem., 1995, 60, 2946, to afford the monobenzyl phosphonate 1.15. The product is then reacted with equimolar amounts of ethyl alaninate 1.16 and dicyclohexyl carbodiimide in pyridine, to yield the amidate product 1.17. The benzyl group is then removed, for example by hydrogenolysis over a palladium catalyst, to give the monoacid product 1.18. This compound is then reacted in a Mitsonobu reaction with ethyl leucinate 1.19, triphenyl phosphine and diethylazodicarboxylate, as described in J. Med. Chem., 1995, 38, 2742, to produce the bisamidate product 1.20. [0232] Using the above procedures, but employing, in place of ethyl leucinate 1.19 or ethyl alaninate 1.16, different aminoesters 1.9, the corresponding products 1.5 are obtained.

[0233] Alternatively, the phosphonic acid 1.6 is converted into the bisamidate 1.5 by use of the coupling reactions described above. The reaction is performed in one step, in which case the nitrogen-related substituents present in the product 1.5 are the same, or in two steps, in which case the nitrogen-related substituents can be different.

[0234] An example of the method is shown in Scheme 1, Example 2. In this procedure, a phosphonic acid 1.6 is reacted in pyridine solution with excess ethyl phenylalaninate 1.21 and dicyclohexylcarbodiimide, for example as described in J. Chem. Soc, Chem. Comm., 1991, 1063, to give the bisamidate product 1.22. [0235] Using the above procedures, but employing, in place of ethyl phenylalaninate, different aminoesters 1.9, the corresponding products 1.5 are obtained.

[0236] As a further alternative, the phosphonic acid 1.6 is converted into the mono or bis-activated derivative 1.7, in which Lv is a leaving group such as chloro, imidazolyl, triisopropylbenzenesulfonyloxy etc. The conversion of phosphonic acids into chlorides 1.7 (Lv = Cl) is effected by reaction with thionyl chloride or oxalyl chloride and the like, as described in Organic Phosphorus Compounds, G. M. Kosolapoff, L. Maeir, eds, Wiley, 1976, p. 17. The conversion of phosphonic acids into monoimidazolides 1.7 (Lv = imidazolyl) is described in J. Med. Chem., 2002, 45, 1284 and in J. Chem. Soc. Chem. Comm., 1991, 312. Alternatively, the phosphonic acid is activated by reaction with triisopropylbenzenesulfonyl chloride, as described in Nucleosides and Nucleotides, 2000, 10, 1885. The activated product is then reacted with the aminoester 1.9, in the presence of a base, to give the bisamidate 1.5. The reaction is performed in one step, in which case the nitrogen substituents present in the product 1.5 are the same, or in two steps, via the intermediate 1.11, in which case the nitrogen substituents can be different.

[0237] Examples of these methods are shown in Scheme 1, Examples 3 and 5. In the procedure illustrated in Scheme 1, Example 3, a phosphonic acid 1.6 is reacted with ten molar equivalents of thionyl chloride, as described in Zh. Obschei Khim., 1958, 28, 1063, to give the dichloro compound 1.23. The product is then reacted at reflux temperature in a polar aprotic solvent such as acetonitrile, and in the presence of a base such as triethylamine, with butyl serinate 1.24 to afford the bisamidate product 1.25.

[0238] Using the above procedures, but employing, in place of butyl serinate 1.24, different aminoesters 1.9, the corresponding products 1.5 are obtained. [0239] In the procedure illustrated in Scheme 1, Example 5, the phosphonic acid 1.6 is reacted, as described in J. Chem. Soc. Chem. Comm., 1991, 312, with carbonyl diimidazole to give the imidazolide 1.32. The product is then reacted in acetonitrile solution at ambient temperature, with one molar equivalent of ethyl alaninate 1.33 to yield the monodisplacement product 1.34. The latter compound is then reacted with carbonyl diimidazole to produce the activated intermediate 1.35, and the product is then reacted, under the same conditions, with ethyl N- methylalaninate 1.33a to give the bisamidate product 1.36. [0240] Using the above procedures, but employing, in place of ethyl alaninate 1.33 or ethyl N-methylalaninate 1.33a, different aminoesters 1.9, the corresponding products 1.5 are obtained.

[0241] The intermediate monoamidate 1.3 is also prepared from the monoester 1.2 by first converting the monoester into the activated derivative 1.8 in which Lv is a leaving group such as halo, imidazolyl etc, using the procedures described above. The product 1.8 is then reacted with an aminoester 1.9 in the presence of a base such as pyridine, to give an intermediate monoamidate product 1.3. The latter compound is then converted, by removal of the R^sl group and coupling of the product with the aminoester 1.9, as described above, into the bisamidate 1.5. [0242] An example of this procedure, in which the phosphonic acid is activated by conversion to the chloro derivative 1.26, is shown in Scheme 1, Example 4. In this procedure, the phosphonic monobenzyl ester 1.15 is reacted, in dichloromethane, with thionyl chloride, as described in Tet. Let., 1994, 35, 4097, to afford the phosphoryl chloride 1.26. The product is then reacted in acetonitrile solution at ambient temperature with one molar equivalent of ethyl 3-amino-2- methylpropionate 1.27 to yield the monoamidate product 1.28. The latter compound is hydrogenated in ethyl acetate over a 5% palladium on carbon catalyst to produce the monoacid product 1.29. The product is subjected to a Mitsonobu coupling procedure, with equimolar amounts of butyl alaninate 1.30, triphenylphosphine, diethylazodicarboxylate and triethylamine in tetrahydrofuran, to give the bisamidate product 1.31.

[0243] Using the above procedures, but employing, in place of ethyl 3-amino- 2-methylpropionate 1.27 or butyl alaninate 1.30, different aminoesters 1.9, the corresponding products 1.5 are obtained.

[0244] The activated phosphonic acid derivative 1.7 is also converted into the bisamidate 1.5 via the diamino compound 1.10. The conversion of activated phosphonic acid derivatives such as phosphoryl chlorides into the corresponding amino analogs 1.10, by reaction with ammonia, is described in Organic Phosphorus Compounds, G. M. Kosolapoff, L. Maeir, eds, Wiley, 1976. The diamino compound 1.10 is then reacted at elevated temperature with a haloester 1.12, in a polar organic solvent such as dimethylformamide, in the presence of a base such as dimethylaminopyridine or potassium carbonate, to yield the bisamidate 1.5.

[0245] An example of this procedure is shown in Scheme 1, Example 6. In this method, a dichlorophosphonate 1.23 is reacted with ammonia to afford the diamide 1.37. The reaction is performed in aqueous, aqueous alcoholic or alcoholic solution, at reflux temperature. The resulting diamino compound is then reacted with two molar equivalents of ethyl 2-bromo-3-methylbutyrate 1.38, in a polar organic solvent such as N-methylpyrrolidinone at ca. 150°C, in the presence of a base such as potassium carbonate, and optionally in the presence of a catalytic amount of potassium iodide, to afford the bisamidate product 1.39. [0246] Using the above procedures, but employing, in place of ethyl 2-bromo- 3-methylbutyrate 1.38, different lialoesters 1.12 the corresponding products 1.5 are obtained.

[0247] The procedures shown in Scheme 1 are also applicable to the preparation of bisamidates in which the aminoester moiety incorporates different functional groups. Scheme 1, Example 7 illustrates the preparation of bisamidates derived from tyrosine. In this procedure, the monoimidazolide 1.32 is reacted with propyl tyrosinate 1.40, as described in Example 5, to yield the monoamidate 1.41. The product is reacted with carbonyl diimidazole to give the imidazolide 1.42, and this material is reacted with a further molar equivalent of propyl tyrosinate to produce the bisamidate product 1.43. [0248] Using the above procedures, but employing, in place of propyl tyrosinate 1.40, different aminoesters 1.9, the corresponding products 1.5 are obtained. The aminoesters employed in the two stages of the above procedure can be the same or different, so that bisamidates with the same or different amino substituents are prepared.

[0249] Scheme 2 illustrates methods for the preparation of phosphonate monoamidates. In one procedure, a phosphonate monoester 1.1 is converted, as described in Scheme 1, into the activated derivative 1.8. This compound is then reacted, as described above, with an aminoester 1.9, in the presence of a base, to afford the monoamidate product 2.1.

[0250] The procedure is illustrated in Scheme 2, Example 1. In this method, a monophenyl phosphonate 2.7 is reacted with, for example, thionyl chloride, as described in J. Gen. Chem. USSR., 1983, 32, 367, to give the chloro product 2.8. The product is then reacted, as described in Scheme 1, with ethyl alaninate 2.9, to yield the amidate 2.10.

[0251] Using the above procedures, but employing, in place of ethyl alaninate 2.9, different aminoesters 1.9, the corresponding products 2.1 are obtained. [0252] Alternatively, the phosphonate monoester 1.1 is coupled, as described in • Scheme 1, with an aminoester 1.9 to produce the amidate 2.1. If necessary, the R^sl substituent is then altered, by initial cleavage to afford the phosphonic acid 2.2. The procedures for this transformation depend on the nature of the R^sl group, and are described above. The phosphonic acid is then transformed into the ester amidate product 2.3, by reaction with the hydroxy compound R^s3OH, in which the group R^s3 is aryl, heteroaryl, alkyl, cycloalkyl, haloalkyl etc, using the same coupling procedures (carbodiimide, Aldrithiol-2, PYBOP, Mitsonobu reaction etc) described in Scheme 1 for the coupling of amines and phosphonic acids.

Scheme 1

[0253] Examples of this method are shown in Scheme 2, Examples and 2 and 3. In the sequence shown in Example 2, a monobenzyl phosphonate 2.11 is transformed by reaction with ethyl alaninate, using one of the methods described above, into the monoamidate 2.12. The benzyl group is then removed by catalytic hydrogenation in ethyl acetate solution over a 5% palladium on carbon catalyst, to afford the phosphonic acid amidate 2.13. The product is then reacted in dichloromethane solution at ambient temperature with equimolar amounts of l-(dimethylaminopropyl)-3-ethylcarbodiimide and trifluoroethanol 2.14, for example as described in Tet. Lett., 2001, 42, 8841, to yield the amidate ester 2.15.

[0254] In the sequence shown in Scheme 2, Example 3, the monoamidate 2.13 is coupled, in tetrahydrofuran solution at ambient temperature, with equimolar amounts of dicyclohexyl carbodiimide and 4-hydroxy-N-methylpiperidine 2.16, to produce the amidate ester product 2.17.

[0255] Using the above procedures, but employing, in place of the ethyl alaninate product 2.12 different monoacids 2.2, and in place of trifluoroethanol 2.14 or 4-hydroxy-N-methylpiperidine 2.16, different hydroxy compounds R^s3OH, the corresponding products 2.3 are obtained. [0256] Alternatively, the activated phosphonate ester 1.8 is reacted with ammonia to yield the amidate 2.4. The product is then reacted, as described in Scheme 1, with a haloester 2.5, in the presence of a base, to produce the amidate product 2.6. If appropriate, the nature of the R^sI group is changed, using the procedures described above, to give the product 2.3. The method is illustrated in Scheme 2, Example 4. In this sequence, the monophenyl phosphoryl chloride 2.18 is reacted, as described in Scheme 1, with ammonia, to yield the amino product 2.19. This material is then reacted in N-methylpyrrolidinone solution at 170°C with butyl 2-bromo-3-phenylpropionate 2.20 and potassium carbonate, to afford the amidate product 2.21.

[0257] Using these procedures, but employing, in place of butyl 2-bromo-3- phenylpropionate 2.20, different haloesters 2.5, the corresponding products 2.6 are obtained.

[0258] The monoamidate products 2.3 are also prepared from the doubly activated phosphonate derivatives 1.7. In this procedure, examples of which are described in Synlett, 1998, 1, 73, the intermediate 1.7 is reacted with a limited amount of the aminoester 1.9 to give the mono-displacement product 1.11. The latter compound is then reacted with the hydroxy compound R³OH in a polar organic solvent such as dimethylformamide, in the presence of a base such as diisopropylethylamine, to yield the monoamidate ester 2.3. [0259] The method is illustrated in Scheme 2, Example 5. In this method, the phosphoryl dichloride 2.22 is reacted in dichloromethane solution with one molar equivalent of ethyl N-methyl tyrosinate 2.23 and dimethylaminopyridine, to generate the monoamidate 2.24. The product is then reacted with phenol 2.25 in dimethylformamide containing potassium carbonate, to yield the ester amidate product 2.26.

[0260] Using these procedures, but employing, in place of ethyl N-methyl tyrosinate 2.23 or phenol 2.25, the aminoesters 1.9 and/or the hydroxy compounds R^s3OH, the corresponding products 2.3 are obtained.

Scheme 2

Scheme 2 Example 4

Scheme 2 Example 5

[0261] Scheme 3 illustrates methods for the preparation of carboalkoxy- substituted phosphonate diesters in which one of the ester groups incorporates a carboalkoxy substituent.

[0262] In one procedure, a phosphonate monoester 1.1, prepared as described above, is coupled, using one of the methods described above, with a hydroxyester 3.1, in which the groups R^s4 and R^s5 are as described in Scheme 1. For example, equimolar amounts of the reactants are coupled in the presence of a carbodiimide such as dicyclohexyl carbodiimide, as described in Aust. J. Chem., 1963, 609, optionally in the presence of dimethylaminopyridine, as described in Tet, 1999, 55, 12997. The reaction is conducted in an inert solvent at ambient temperature. [0263] The procedure is illustrated in Scheme 3, Example 1. In this method, a monophenyl phosphonate 3.9 is coupled, in dichloromethane solution in the presence of dicyclohexyl carbodiimide, with ethyl 3-hydroxy-2-methylpropionate 3.10 to yield the phosphonate mixed diester 3.11.

[0264] Using this procedure, but employing, in place of ethyl 3-hydroxy-2- methylpropionate 3.10, different hydroxyesters 3.1, the corresponding products 3.2 are obtained.

[0265] The conversion of a phosphonate monoester 1.1 into a mixed diester 3.2 is also accomplished by means of a Mitsonobu coupling reaction with the hydroxyester 3.1, as described in Org. Lett., 2001, 643. In this method, the reactants 1.1 and 3.1 are combined in a polar solvent such as tetrahydrofuran, in the presence of a triarylphosphine and a dialkyl azodicarboxylate, to give the mixed diester 3.2. The R^sl substituent is varied by cleavage, using the methods described previously, to afford the monoacid product 3.3. The product is then coupled, for example using methods described above, with the hydroxy compound R^s3OH, to give the diester product 3.4.

[0266] The procedure is illustrated in Scheme 3, Example 2. In this method, a monoallyl phosphonate 3.12 is coupled in tetrahydrofuran solution, in the presence of triphenylphosphine and diethylazodicarboxylate, with ethyl lactate 3.13 to give the mixed diester 3.14. The product is reacted with tris(triphenylphosphine) rhodium chloride (Wilkinson catalyst) in acetonitrile, as described previously, to remove the allyl group and produce the monoacid product 3.15. The latter compound is then coupled, in pyridine solution at ambient temperature, in the presence of dicyclohexyl carbodiimide, with one molar equivalent of 3-hydroxypyridine 3.16 to yield the mixed diester 3.17. [0267] Using the above procedures, but employing, in place of the ethyl lactate 3.13 or 3-hydroxypyridine, a different hydroxyester 3.1 and/or a different hydroxy compound R^s3OH, the corresponding products 3.4 are obtained. [0268] The mixed diesters 3.2 are also obtained from the monoesters 1.1 via the intermediacy of the activated monoesters 3.5. In this procedure, the monoester 1.1 is converted into the activated compound 3.5 by reaction with, for example, phosphorus pentachloride, as described in J. Org. Chem., 2001, 66, 329, or with thionyl chloride or oxalyl chloride (Lv = Cl), or with triisopropylbenzenesulfonyl chloride in pyridine, as described in Nucleosides and Nucleotides, 2000, 19, 1885, or with carbonyl diimidazole, as described in J. Med. Chem., 2002, 45, 1284. The resultant activated monoester is then reacted with the hydroxyester 3.1, as described above, to yield the mixed diester 3.2.

[0269] The procedure is illustrated in Scheme 3, Example 3. In this sequence, a monophenyl phosphonate 3.9 is reacted, in acetonitrile solution at 70°C, with ten equivalents of thionyl chloride, so as to produce the phosphoryl chloride 3.19. The product is then reacted with ethyl 4-carbamoyl-2-hydroxybutyrate 3.20 in dichloromethane containing triethylamine, to give the mixed diester 3.21. [0270] Using the above procedures, but employing, in place of ethyl 4- carbamoyl-2-hydroxybutyrate 3.20, different hydroxyesters 3.1, the corresponding products 3.2 are obtained.

[0271] The mixed phosphonate diesters are also obtained by an alternative route for incorporation of the R^s3O group into intermediates 3.3 in which the hydroxyester moiety is already incorporated. In this procedure, the monoacid intermediate 3.3 is converted into the activated derivative 3.6 in which Lv is a leaving group such as chloro, imidazole, and the like, as previously described.

The activated intermediate is then reacted with the hydroxy compound R^s3OH, in the presence of a base, to yield the mixed diester product 3.4.

[0272] The method is illustrated in Scheme 3, Example 4. In this sequence, the phosphonate monoacid 3.22 is reacted with trichloromethanesulfonyl chloride in tetrahydrofuran containing collidine, as described in J. Med. Chem., 1995, 38,

4648, to produce the trichloromethanesulfonyloxy product 3.23. This compound is reacted with 3-(morpholinomethyl)phenol 3.24 in dichloromethane containing triethylamine, to yield the mixed diester product 3.25.

[0273] Using the above procedures, but employing, in place of with

3-(morpholinomethyl)phenol 3.24, different carbinols R^s3OH, the corresponding products 3.4 are obtained.

[0274] The phosphonate esters 3.4 are also obtained by means of alkylation reactions performed on the monoesters 1.1. The reaction between the monoacid

1.1 and the haloester 3.7 is performed in a polar solvent in the presence of a base such as diisopropylethylamine, as described in Anal. Chem., 1987, 59, 1056, or triethylamine, as described in J. Med. Chem., 1995, 38, 1372, or in a non-polar¹ solvent such as benzene, in the presence of 18-crown-6, as described in Syn.

Comm., 1995, 25, 3565.

[0275] The method is illustrated in Scheme 3, Example 5. In this procedure, the monoacid 3.26 is reacted with ethyl 2-bromo-3-phenylpropionate 3.27 and diisopropylethylamine in dimethylformamide at 8O°C to afford the mixed diester product 3.28.

[0276] Using the above procedure, but employing, in place of ethyl 2-bromo-3- phenylpropionate 3.27, different haloesters 3.7, the corresponding products 3.4 are obtained. Scheme 3

3.22 3.23 3.25

Scheme 3 Example 5

)CO₂Et

3.26 3.28

[0277] Scheme 4 illustrates methods for the preparation of phosphonate diesters in which both the ester substituents incorporate carboalkoxy groups.

[0278] The compounds are prepared directly or indirectly from the phosphonic acids 1.6. In one alternative, the phosphonic acid is coupled with the hydroxyester 4.2, using the conditions described previously in Schemes 1 - 3, such as coupling reactions using dicyclohexyl carbodiimide or similar reagents, or under the conditions of the Mitsonobu reaction, to afford the diester product

4.3 in which the ester substituents are identical.

[0279] This method is illustrated in Scheme 4, Example 1. In this procedure, the phosphonic acid 1.6 is reacted with three molar equivalents of butyl lactate

4.5 in the presence of Aldrithiol-2 and triphenyl phosphine in pyridine at ca.

70°C, to afford the diester 4.6.

[0280] Using the above procedure, but employing, in place of butyl lactate 4.5, different hydroxyesters 4.2, the corresponding products 4.3 are obtained.

[0281] Alternatively, the diesters 4.3 are obtained by alkylation of the phosphonic acid 1.6 with a haloester 4.1. The alkylation reaction is performed as described in Scheme 3 for the preparation of the esters 3.4.

[0282] This method is illustrated in Scheme 4, Example 2. In this procedure, the phosphonic acid 1.6 is reacted with excess ethyl 3-bromo-2-methylpropionate

4.7 and diisopropylethylamine in dimethylformamide at ca. 80°C, as described in

Anal. Chem., 1987, 59, 1056, to produce the diester 4.8. [0283] Using the above procedure, but employing, in place of ethyl 3-bromo-2- methylpropionate 4.7, different haloesters 4.1, the corresponding products 4.3 are obtained.

[0284] The diesters 4.3 are also obtained by displacement reactions of activated derivatives 1.7 of the phosphonic acid with the hydroxyesters 4.2. The displacement reaction is performed in a polar solvent in the presence of a suitable base, as described in Scheme 3. The displacement reaction is performed in the presence of an excess of the hydroxyester, to afford the diester product 4.3 in which the ester substituents are identical, or sequentially with limited amounts of different hydroxyesters, to prepare diesters 4.3 in which the ester substituents are different.

[0285] The methods are illustrated in Scheme 4, Examples 3 and 4. As shown in Example 3, the phosphoryl dichloride 2.22 is reacted with three molar equivalents of ethyl 3-hydroxy-2-(hydroxymethyl)propionate 4.9 in tetrahydrofuran containing potassium carbonate, to obtain the diester product

4.10.

[0286] Using the above procedure, but employing, in place of ethyl 3-hydroxy-

2-(hydroxymethyl)propionate 4.9, different hydroxyesters 4.2, the corresponding products 4.3 are obtained.

[0287] Scheme 4, Example 4 depicts the displacement reaction between equimolar amounts of the phosphoryl dichloride 2.22 and ethyl 2-methyl-3- hydroxypropionate 4.11, to yield the monoester product 4.12. The reaction is conducted in acetonitrile at 7O°C in the presence of diisopropylethylamine. The product 4.12 is then reacted, under the same conditions, with one molar equivalent of ethyl lactate 4.13, to give the diester product 4.14.

[0288] Using the above procedures, but employing, in place of ethyl 2-methyl-

3-hydroxypropionate 4.11 and ethyl lactate 4.13, sequential reactions with different hydroxyesters 4.2, the corresponding products 4.3 are obtained. Scheme 4

1.7 4.4 Scheme 4 Example 1

1.6 4.6 Scheme 4 Example 2

1.6 4.8 Scheme 4 Example 3

Scheme 4 Example 4

2.22 4.12 4.14 Scheme 1002

[0100] Amino alkyl phosphonate compounds 8G9:

are a generic representative of compounds 811, 813, 814, 816 and 818. Some methods to prepare embodiments of 809 are shown in Scheme 1002. Commercial amino phosphonic acid 810 was protected as carbamate 811. The phosphonic acid 811 was converted to phosphonate 812 upon treatment with ROH in the presence of DCC or other conventional coupling reagents. Coupling of phosphonic acid 811 with esters of amino acid 820 provided bisamidate 817. Conversion of acid 811 to bisphenyl phosphonate followed by hydrolysis gave mono-phosphonic acid 814 (Cbz = C₆H₅CH₂C(O)-), which was then transformed to mono-phosphonic amidate 815. Carbamates 813, 816 and 818 were converted to their corresponding amines upon hydrogenation. Compounds 811, 813, 814, 816 and 818 are useful intermediates to form the phosphonate compounds of the embodiments.

[0289] Following the similar procedures, replacement of amino acid esters 820 with lactates 821 (Scheme 1003) provides mono-phosphonic lactates 823. Lactates 823 are useful intermediates to form the phosphonate compounds of the embodiments. Scheme 1003

Example 1

[0290] To a solution of 2-aminoethylphosphonic acid (1.26 g, 10.1 mmol) in 2N NaOH (10.1 mL, 20.2 mmol) was added benzyl chloroformate (1.7 mL, 12.1 mmol). After the reaction mixture was stirred for 2 d at room temperature, the mixture was partitioned between Et₂O and water. The aqueous phase was acidified with 6N HCl until pH=2. The resulting colorless solid was dissolved in MeOH (75 mL) and treated with Dowex 50WX8-200 (7 g). After the mixture was stirred for 30 minutes, it was filtered and evaporated under reduced pressure to give carbamate 28 (2.37 g, 91%) as a colorless solid (Scheme 1005). [0291] To a solution of carbamate 28 (2.35 g, 9.1 mmol) in pyridine (40 niL) was added phenol (8.53 g, 90.6 mmol) and 1,3-dicyclohexylcarbodiimide (7.47 g, 36.2 mmol). After the reaction mixture was warmed to 70⁰C and stirred for 5 h, the mixture was diluted with CH₃CN and filtered. The filtrate was concentrated under reduced pressure and diluted with EtOAc. The organic phase was washed with sat. NH₄Cl, sat. NaHCO₃, and brine, then dried over Na₂SO₄, filtered, and evaporated under reduced pressure. The crude product was chromatographed on silica gel twice (eluting 40-60% EtOAc/hexane) to give phosphonate 29 (2.13 g, 57%) as a colorless solid.

[0292] To a solution of phosphonate 29 (262 mg, 0.637 mmol) in iPrOH (5 mL) was added TFA (0.05 mL, 0.637 mmol) and 10% Pd/C (26 mg). After the reaction mixture was stirred under H₂ atmosphere (balloon) for 1 h, the mixture was filtered through Celite. The filtrate was evaporated under reduced pressure to give amine 30 (249 mg, 100%) as a colorless oil (Scheme 1005). [0293] The strategies available for synthesis of the core of the prodrug compounds of the embodiments include for example: [0294] The strategies available for synthesis of the core of the prodrug compounds of the embodiments include for example:

General Synthesis of 2' -C-Branched Nucleosides [0295] 2 '-C-Branched ribonucleosides of Formula I:

wherein T, Y, and A⁰ are as defined above, can be prepared by one of the following general methods.

Convergent approach: Glycosylation ofNucleobase with Appropriately Modified Sugar [0296] The key starting material of this process is an appropriately substituted sugar with 2'-OH and 2'-H with the appropriate leaving group, for example, an acyl group or a chloro, bromo, fluoro or iodo group at the 1 -position. The sugar can be purchased or can be prepared by any known means including standard epimerization, substitution, oxidation and/or reduction techniques. For example, commercially available 1,3,5- tri-O-benzoyl-α-D-ribofuranose (Pfanstiel Laboratories, Inc.) can be used. The substituted sugar can then be oxidized with the appropriate oxidizing agent in a compatible solvent at a suitable temperature to yield the 2 '-modified sugar. Possible oxidizing agents are, for example, Dess- Martin periodine reagent, Ac₂O+ DCC in DMSO, Swern oxidation (DMSO, oxalyl chloride, triethylamine), Jones reagent (a mixture of chromic acid and sulfuric acid), Collins 's reagent (dipyridine Cr(VI) oxide, Corey's reagent (pyridinium chlorochromate), pyridinium dichromate, acid dichromate, potassium permanganate, MnO₂, ruthenium tetraoxide, phase transfer catalysts such as chromic acid or permanganate supported on a polymer, Cl₂-pyridine, H₂O₂- ammonium molybdate, NaBrO₂-CAN, NaOCl in HOAc, copper chromite, copper oxide, Raney nickel, palladium acetate, Meerwin-Pondorf-Verley reagent (aluminum t-butoxide with another ketone) and N-bromosuccinimide. [0297] Coupling of an organometallic carbon nucleophile, such as a Grignard reagent, an organolithium, lithium dialkylcopper or SiMe₄ in TBAF with the ketone with the appropriate non-protic solvent at a suitable temperature, yields the 2'-methyl sugar. For example, CH₃MgBr/TiCl₄ or CH₃MgBr/CeCl₃ can be used as described in Wolfe et al. 1997. J. Org. Chem. 62: 1754-1759. The methylated sugar can be optionally protected with a suitable protecting group, preferably with an acyl, substituted alkyl or silyl group, by methods well known to those skilled in the art, as taught by Greene et al. Protective Groups in Organic Synthesis, John Wiley and Sons, Second Edition, 1991.

[0298] The optionally protected sugar can then be coupled to the purine base by methods well known to those skilled in the art, as taught by Townsend Chemistry of Nucleosides and Nucleotides, Plenum Press, 1994. For example, an acylated sugar can be coupled to a silylated base with a Lewis acid, such as tin tetrachloride, titanium tetrachloride or trimethylsilyltriflate in the appropriate solvent at a suitable temperature. Alternatively, a halo-sugar can be coupled to a silylated base with the presence of trimethylsilyltriflate. [0299] In addition to the above, the 2'-C-substituted sugars used in the synthetic methods described herein are well known in the art and are described, for example, by Sommadossi, et al.¹⁰ and by Carrol, et al.¹¹' ¹² all of which are incorporated herein by reference in their entirety.

[0300] Scheme 1 below describes the alternative synthesis of a protected sugar that is useful for coupling to the bases described herein.

SCHEME 1

where Ph is phenyl and X is a suitable leaving group such as halo.

[0301] Formation of sugar a in Scheme 1, above, is accomplished as described by Mandal, S.B., et al, Synth. Commun,, 1993, 9, page 1239, starting from commercial D-ribose. Protection of the hydroxyl groups to form sugar b is described in Witty, D.R., et al, Tet. Lett., 1990, 31, page 4787. Sugar c and d are prepared using the method of Ning, J. et al, Carbohydr. Res., 2001, 330, page 165, and methods described herein. Sugar e is prepared by using a modification of the Grignard reaction with CH₃MgBr or other appropriate organometallic as described herein (with no titanium/cerium needed). Finally the halogenated sugar (X = halo) used in the subsequent coupling reaction is prepared using the same protection method as used in to make sugar b above. The halogenation is . described in Seela, U.S. Patent No. 6,211,158.

[0302] Subsequently, any of the described nucleosides can be deprotected by methods well known to those skilled in the art, as taught by Greene et al Protective Groups in Organic Synthesis, Jon Wiley and Sons, Second Edition, 1991. [0303] An alternative approach to making protected sugars useful for coupling to heterocyclic bases is detailed in Scheme_, 2 below.

Scheme 2

[0304] In Scheme 2, methylation of the hydroxyl group of compound 1 proceeds via conventional methodology to provide for compound 2. The 2, 3 and 5 hydroxyl groups of the compound 2 are each protected with 2,4-dichlorobenzyl groups to provide for compound 3. Selective deprotection of the 2-(2',4'- dichlorobenzyl) group on compound 3 proceeds via contact with stannous chloride in a suitable solvent such as methylene chloride, chloroform, and the like at reduced temperatures, e.g., ~ 0 to 5°C, until reaction completion, e.g., 24-72 hours. Oxidation of the 2-hydroxyl group proceeds as described herein to provide for compound 7. Methylation also proceeds as described herein to provide for compound 8.

Linear Approach: Modification of a pre-formed nucleoside [0305] The key starting material for this process is an appropriately substituted nucleoside with a 2'-OH and 2'-H. The nucleoside can be purchased or can be prepared by any known means including standard coupling techniques. The nucleoside can be optionally protected with suitable protecting groups, preferably with acyl, substituted alkyl or silyl groups, by methods well known to those skilled in the art, as taught by Greene et al. Protective Groups in Organic Synthesis, John Wiley and Sons, Second Edition, 1991. [0306] The appropriately protected nucleoside can then be oxidized with the appropriate oxidizing agent in a compatible solvent at a suitable temperature to yield the 2'-modified sugar. Possible oxidizing agents are, for example, Dess- Martin periodine reagent, Ac₂O+ DCC in DMSO, Swern oxidation (DMSO, oxalyl chloride, triethylamine), Jones reagent (a mixture of chromic acid and sulfuric acid), Collins' s reagent (dipyridine Cr(VI) oxide, Corey's reagent (pyridinium chlorochromate), pyridinium dichromate, acid dichromate, potassium permanganate, MnO₂ ruthenium tetroxide, phase transfer catalysts such as chromic acid or permanganate supported on a polymer, Cl₂-pyridine, H₂O₂- ammonium molybdate, NaBrO₂-CAN, NaOCl in HOAc, copper chromite, copper oxide, Raney nickel, palladium acetate, Meerwin-Pondorf-Verley reagent (aluminum t-butoxide with another ketone) and N-bromosuccinimide. [0307] Coupling of an organometallic carbon nucleophile, such as a Grignard reagent, an organolithium, lithium dialkylcopper or CH₃SiMe₃ in TBAF with the ketone with the appropriate non-protic solvent at a suitable temperature, yields the alkyl substituted nucleoside. Isolation of the appropriate isomer is conducted as needed.

[0308] Subsequently, the nucleoside can be deprotected by methods well known to those skilled in the art, as taught by Greene et al. Protective Groups in Organic Synthesis, John Wiley and Sons, Second Edition, 1991. [0309] In one embodiment, the D-enantiomers are preferred. However, L- enantiomers are also contemplated to be useful herein. The L-enantiomers corresponding to the compounds of the embodiments can be prepared following the same foregoing general methods, beginning with the corresponding L-sugar or nucleoside as starting material. In a particular embodiment, the 2'-C-branched ribonucleoside is desired.

[0310] The compounds of the embodiments may be prepared by various methods known in the art of organic chemistry in general and nucleoside and nucleotide analogue synthesis in particular. The starting materials for the syntheses are either readily available from commercial sources or are known or may be prepared by techniques known in the art. General reviews of the preparation of nucleoside and nucleotide analogues are included in the following:

Michelson A.M. "The Chemistry of Nucleosides and Nucleotides " Academic Press, New York, 1963.

Goodman L. "Basic Principles in Nucleic Acid Chemistry," Academic Press, New York, 1974, vol. 1, Ch. 2.

"Synthetic Procedures in Nucleic Acid Chemistry " Eds. Zorbach W. & Tipson R., Wiley, New York, 1973, vol. 1 & 2.

[0311] The 5-substituted acetylenyl-pyrrolo[2,3-d]pyrimidinyl nucleoside derivatives of the present embodiments can be synthesized using the methods depicted in Scheme 3 below.

[0312] . A convergent approach for preparing the pyrrolo[2,3-d]pyrimidinyl nucleosides is shown in Scheme 3 below. First commercially available .4-chloropyrrolo[2,3-d]pyrimidine 11 is halogenated at the 5-position (compound 12) using well known methods, for example, the halogenation method described in A. Gangjee et at., J. Med. Chem. (2003) 46, 591. Intermediate compound 12 may be isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like. Alternatively, compound 12 may be isolated and used in the next step without further purification. [0313] 5-(Substituted alkynyl)-4-chloropyrrolo[2,3-d]pyrimidine 13 is prepared using Sonigashira conditions as described in A. Gangjee et al, (J. Med. Chem. (2003) 46, 591) to yield compound 13. Intermediate compound 13 may be isolated- and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like. Alternatively compound 13 may be isolated and used in the next step without further purification. [0314] Compound 13 is coupled to protected 2-methyl substituted sugar 8 (the 11,12 synthesis of which is described above and by Carroll, et al, ) using conditions well known in the art. For example, l-O-methyl-3,5-bis-(9-(2,4- dichlorophenylmethyl)-2'-C-methyl-β-D-ribofuranoside 8 is dissolved in a dry inert solvent, such as dichloromethane, chloroform, carbon tetrachloride and the like, and then the solution is cooled to about 0°C. Afterwards, an excess of HBr or other appropriate reagent, in acetic acid, is added drop wise. This reaction is run for typically at about 0°C for about 1 hour or at ambient temperature for about 2.5 hours or until substantially complete as determined by conventional techniques such as tic. The resulting brominated sugar mixture is isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like. Alternatively this intermediate may be isolated and used in the next step without further purification. The resulting brominated sugar mixture is co-evaporated, preferably with dry toluene, dissolved in a suitable inert diluent such as dry acetonitrile and stirred with the sodium salt of compound 13 at room temperature over night. The sodium salt of compound 13 is prepared in an inert atmosphere by suspending compound 13 in a dry inert solvent such as, acetonitrile and the like, with NaH dispersed in oil. The reaction is run for about 2 to about 24 hours at a temperature of about 0 to about 4O°C. Finally compound 15 is isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like. Alternatively, this intermediate may be isolated and used in the next step without further purification.

[0315] Deprotection of compound 15 using standard methods affords compound 16, which is, in some cases, converted to the 4-amino derivative (compound 17) using methods well known in the art. For example, compound 16 is added to liquid ammonia at about -8O°C and is warmed to about 80°C for about 24 to about 48 hours. Compound 17 is isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like.

Scheme 3

where Z is as defined herein and DCB is 2,4-dichlorobenzyl.

[0316] In an alternative approach, the l-[5-(substituted alkynyl)- 4-aminopyrrolo[2,3-d]pyrimidine]-2'-C-methyl-β-D-ribofuranoside compounds can be prepared using the method illustrated in Scheme 4 below. [0317] Compound 12, prepared as described above is coupled to the protected sugar 8, using the techniques described for the preparation of compound 15 in Scheme 3 above to provide for compound 19. Deprotection of compound 19, using standard methods, provides compound 20.

[0318] From compound 20, the l-[5-(substituted alkynyl)-4-amino-pyrrolo[2,3- d]pyrimidine]-2'-C-methyl-β-D-ribofuranoside compounds can be prepared by first converting the 4-chloro group to an amino group, using the technique described for the preparation of compound 17 from compound 16 in scheme 3 above to provide for compound 21, followed by coupling using Sonigashira conditions as described in A. Gangjee et al, (J. Med. Chem. (2003) 46, 591) to form the substituted alkynyl derivative, compound 17. [0319] In some cases the l-[5-(substituted alkynyl)-4-amino-pyrrolo[2,3- dJpyrimidine]-2'-C-methyl-β-D-ribofuranoside compounds can be prepared from compound 20 by first converting the 5-iodo group to the the 5-substituted alkynyl derivative (compound 16), followed by conversion of the 4-chloro group to the amine (compound 17). The methods for each of these transformations are detailed above.

Scheme 4

17 where Z and DCB are as described above.

[0320] The 5-nitropyrrolo[2,3-d]pyrimidinyl nucleoside derivatives of the present embodiments can be synthesized using the methods depicted in Scheme 5 below.

[0321] A convergent approach for preparing the pyrrolo[2,3-d]pyrimidinyl nucleosides is shown in Scheme 3 below. First commercially available 4-chloropyrrolo[2,3-d]pyrimidine, compound 11, is coupled to protected 2- methyl substituted sugar 8 (the synthesis of which is described above and by Carrol, et al., ⁿ'ⁿ) using conditions well known in the art to provide for compound 52. For example, l-O-methyl-3,5-bis-O-(2_s4-dichlorophenylmethyl)- 2'-C-methyl-D-ribofuranoside 8 is dissolved in a dry inert solvent, such as dichloromethane, chloroform, carbon tetrachloride and the like, and then the solution is cooled to about O°C. Afterwards, an excess of HBr or other appropriate reagent, in acetic acid, is added drop wise. This reaction is typically run about 1 to about 4 hours at temperature at about 0 to about 25 °C, or until substantially complete as determined by conventional techniques such as TLC. The resulting brominated sugar mixture is isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like. Alternatively this intermediate may be isolated and used in the next step without further purification. The resulting brominated sugar mixture is co- evaporated, preferably with dry toluene, dissolved in a suitable inert diluent such as dry acetonitrile and stirred with the sodium salt of compound 11 at room temperature over night. The sodium salt of compound 11 is prepared in an inert atmosphere by suspending compound 11 in a dry inert solvent such as, acetonitrile and the like, with NaH dispersed in oil. The reaction is run for about 2 to about 24 hours at a temperature of about 0 to about 4O°C. Finally, compound 12 is isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like. Alternatively, this intermediate may be isolated and used in the next step without further purification.

[0322] The hydroxyl protecting groups of compound 52 are removed using standard methods to afford compound 53, which is then animated using methods well known in the art. For example, compound 53 is added to liquid ammonia at about -8O°C and is warmed to about 80°C for about 24 to about 48 hours to provide for compound 54 which can be isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like or, alternatively, used in the next step without purification and/or isolation.

[0323] The hydroxy groups of compound 54 are then protected by acetylation with an excess of acetyl chloride in acetic acid using conventional techniques to provide for compound 55 which can be isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like or, alternatively, used in the next step without purification and/or isolation. Scheme 5

where DCB is 2,4-dichlorobenzyl and Ac is acetyl

[0324] Nitration of compound 55 again occurs under conventional conditions using a mixture of nitric acid (HNO₃), and sulfuric acid (H₂SO₄), in dichloromethane which provides for compound 56 which can be isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like or, alternatively, used in the next step without purification and/or isolation.

[0325] Finally, the acetyl protecting groups on compound 56 are removed under conventional conditions to provide for the 5-nitro derivative, compound 57. This compound can be isolated and purified using standard techniques such as chromatography, precipitation, crystallization, filtration, and the like. [0326] Preparation of compounds where W, W¹ or W² is other than hydrogen, using the compounds prepared in the Schemes above as the starting materials, can be accomplished using the methods described in the following reviews of prodrug preparation:

1) Cooperwood, J. S. et al, "Nucleoside and Nucleotide prodrugs, " in Ed(s) Chu, C. K. Recent Advances in Nucleosides (2002), 92-147.

2) Zemlicka, J. et al. , Biochimica et Biophysica Acta (2002), 158(2-3), 276- 286.

3) Wagner, C. et al, Medicinal Research Reviews (2002), 20(6), 417-451.

4) Meier, C. et al, Synlett (1998), (3), 233-242.

[0327] For example, conversion of the 5 '-hydroxy 1 group of the l-[5- (substituted alkynyl)-4-amino-pyrrolo[2,3-d]pyrimidine]-2'-C-methyl-β-D- ribofuranoside compounds to a phospho, diphospho or triphospho-analog can prepared using the methods describe in D.W. Hutchinson, (Ed. Leroy b. Townsend) "The Synthesis, reaction and Properties of Nucleoside Mono-, Di-, Tri-, and tertaphosphate and Nucleosides with Changes in the Phosphoryl Residue, " Chemistry of Nucleosides and Nucleotides, Plenum Press, (1991) 2. [0328] The preparation of amino acid esters on the ribofuranoside can be accomplished as shown in Scheme 6 below:

SCHEME 6

[0329] The desired Boc-protected amino acid and N,N'-carbonyldiimidazole are dissolved in an inert solvent such as THF. The reaction mixture is held between about 20 and about 40°C for about 0.5 to 24 hours. A solution containing an slight excess of the desired nucleoside in an inert solvent such as DMF, is added to the Boc-protected amino acid mixture and is heated at about 40 to about 8O°C for about 2 to about 24 hours. A mixture of structural isomers is isolated and separated using conventional techniques such as evaporation, precipitation, filtration, crystallization, chromatography and the like. [0330] The desired ester is then acidified using, for example, 1 : 1 v/v TFA/DCM solution for about 0.1 to about 1 hour about 20 and about 40°C and evaporated. The residue is dissolved in water and held at about 0 to about 3O⁰C for about 2 to about 24 hours. The mixture can be separated and the desired product isolated by RP-HPLC using standard techniques and conditions. [0331] While the scheme above demonstrates the production of deazapurine prodrugs, this process can be used on any desired nucleoside compound. Likewise, the amino acid may be protected with any protective group appropriate to the reaction conditions. These protective groups are well known in the art.

SCHEME 7

where T is as defined above.

[0332] Compound 1 is dissolved in a dry solvent, such as pyridine, and a silylhalide, such as tert-butylchlorodiphenylsilane, is added to form a protecting group at the 5 '-position on the sugar. Any protecting group which can be directed to the 5 '-position and can be removed orthongally to the final desired 3'- ester can be used. This reaction is run for about 4 to 24 hours at a temperature of about 10 to 40 °C. The desired acyl chloride is added to the protected nucleoside, compound 30, and stirred for about 4 to about 24 hours to form compound 31. Which can be isolated and purified using standard techniques such as isolation, crystallization, extraction, filtration, chromatography and the like. Compound 32 is prepared by removing the protecting group at the 5 '-position. This can be accomplished by reacting Compound 30 with a IM solution of tetrabutylammonium fluoride in THF. The final product is isolated and purified using standard techniques such as isolation, crystallization, extraction, filtration, chromatography and the like.

[0333] While the scheme above demonstrates the production of deazapurine prodrugs, this process can be used on any desired nucleoside compound

UTILITY, TESTING, AND ADMINISTRATION

Utility

[0334] The present embodiments provides novel compounds possessing antiviral activity, including hepatitis C virus. The compounds of the embodiments inhibit viral replication by inhibiting the enzymes involved in replication, including RNA dependent RNA polymerase. They may also inhibit other enzymes utilized in the activity or proliferation of viruses in the flaviviridae family, such as HCV.

[0335] The compounds of the present embodiments can also be used as prodrug nucleosides. As such they are taken up into the cells and can be intracellularly phosphorylated by kinases to the triphosphate and are then inhibitors of the polymerase (NS5b) and/or act as chain-terminators.

[0336] Compounds of the embodiments may be used alone or in combination with other compounds to treat viruses.

Administration and Pharmaceutical Composition

[0337] In general, the compounds of the embodiments will be administered in a therapeutically effective amount by any of the accepted modes of administration for agents that serve similar utilities. The actual amount of the compound of the embodiments, i.e., the active ingredient, will depend upon numerous factors such as the severity of the disease to be treated, the age and relative health of the subject, the potency of the compound used, the route and form of administration, and other factors. The drug can be administered more than once a day, preferably once or twice a day.

[0338] Therapeutically effective amounts of compounds of Formula I may range from about 0.05 to about 50 mg per kilogram body weight of the recipient per day; preferably about 0.01-25 mg/kg/day, more preferably from about 0.5 to about 10 mg/kg/day. Thus, for administration to about 70 kg person, the dosage range would most preferably be about 35-70 mg per day. [0339] In general, compounds of the embodiments will be administered as pharmaceutical compositions by any one of the following routes: oral, systemic (e.g., transdermal, intranasal or by suppository), or parenteral (e.g., intramuscular, intravenous or subcutaneous) administration. The preferred manner of administration is oral using a convenient daily dosage regimen that can be adjusted according to the degree of affliction. Compositions can take the form of tablets, pills, capsules, semisolids, powders, sustained release formulations, solutions, suspensions, elixirs, aerosols, or any other appropriate compositions. Another preferred manner for administering compounds of the embodiments is inhalation. This is an effective method for delivering a therapeutic agent directly to the respiratory tract (see U. S. Patent 5,607,915).

[0340] The choice of formulation depends on various factors such as the mode of drug administration and bioavailability of the drug substance. For delivery via inhalation the compound can be formulated as liquid solution, suspensions, aerosol propellants or dry powder and loaded into a suitable dispenser for administration. There are several types of pharmaceutical inhalation devices- nebulizer inhalers, metered dose inhalers (MDI) and dry powder inhalers (DPI). Nebulizer devices produce a stream of high velocity air that causes the therapeutic agents (which are formulated in a liquid form) to spray as a mist that is carried into the patient's respiratory tract. MDPs typically are formulation packaged with a compressed gas. Upon actuation, the device discharges a measured amount of therapeutic agent by compressed gas, thus affording a reliable method of administering a set amount of agent. DPI dispenses therapeutic agents in the form of a free flowing powder that can be dispersed in the patient's inspiratory air-stream during breathing by the device. In order to achieve a free flowing powder, the therapeutic agent is formulated with an excipient such as lactose. A measured amount of the therapeutic agent is stored in a capsule form and is dispensed with each actuation.

[0341] Recently, pharmaceutical formulations have been developed especially for drugs that show poor bioavailability based upon the principle that - bioavailability can be increased by increasing the surface area i.e., decreasing particle size. For example, U.S. Pat. No. 4,107,288 describes a pharmaceutical formulation having particles in the size range from 10 to 1,000 nm in which the active material is supported on a crosslinked matrix of macromolecules. U.S. Patent No. 5,145,684 describes the production of a pharmaceutical formulation in which the drug substance is pulverized to nanoparticles (average particle size of 400 nm) in the presence of a surface modifier and then dispersed in a liquid medium to give a pharmaceutical formulation that exhibits remarkably high bioavailability.

[0342] The compositions are comprised of in general, a compound of Formula I in combination with at least one pharmaceutically acceptable excipient. Acceptable excipients are non-toxic, aid administration, and do not adversely affect the therapeutic benefit of the compound of Formula I. Such excipient may be any solid, liquid, semi-solid or, in the case of an aerosol composition, gaseous excipient that is generally available to one of skill in the art. [0343] Solid pharmaceutical excipients include starch, cellulose, talc, glucose, lactose, sucrose, gelatin, malt, rice, flour, chalk, silica gel, magnesium stearate, sodium stearate, glycerol monostearate, sodium chloride, dried skim milk and the like. Liquid and semisolid excipients may be selected from glycerol, propylene glycol, water, ethanol and various oils, including those of petroleum, animal, vegetable or synthetic origin, e.g., peanut oil, soybean oil, mineral oil, sesame oil, etc. Preferred liquid carriers, particularly for injectable solutions, include water, saline, aqueous dextrose, and glycols.

[0344] Compressed gases may be used to disperse a compound of the embodiments in aerosol form. Inert gases suitable for this purpose are nitrogen, carbon dioxide, etc. Other suitable pharmaceutical excipients and their formulations are described in Remington's Pharmaceutical Sciences, edited by E. W. Martin (Mack Publishing Company, 18th ed., 1990). [0345] The amount of the compound in a formulation can vary within the full range employed by those skilled in the art. Typically, the formulation will contain, on a weight percent (wt%) basis, from about 0.01-99.99 wt% of a compound of Formula I based on the total formulation, with the balance being one or more suitable pharmaceutical excipients. Preferably, the compound is present at a level of about 1-80 wt%. Representative pharmaceutical formulations containing a compound of Formula I are described below. [0346] Additionally, the present embodiments are directed to a pharmaceutical composition comprising a therapeutically effective amount of a compound of the present embodiments in combination with a therapeutically effective amount of another active agent against RNA-dependent RNA virus and, in particular, against HCV. Agents active against HCV include, but are not limited to, ribavirin, levovirin, viramidine, thymosin alpha- 1, an inhibitor of HCV NS3 serine protease, interferon-α, pegylated interferon-α (peginterferon-α), a combination of interferon-α and ribavirin, a combination of peginterferon-α and ribavirin, a combination of interferon-α and levovirin, and a combination of peginterferon-α and levovirin. Interferon-α includes, but is not limited to, recombinant interferon-α2a (such as Roferon interferon available from Hoffman- LaRoche, Nutley, NJ), interferon-α2b (such as Intron-A interferon available from Schering Corp., Kenilworth, New Jersey, USA), a consensus interferon, and a purified interferon-α product. For a discussion of ribavirin and its activity against HCV, see J.O. Saunders and S.A. Raybuck, "Inosine Monophosphate Dehydrogenase: Consideration of Structure, Kinetics and Therapeutic Potential," Ann. Rep. Med Chem., 35:201-210 (2000).

Biological Examples

Example 1. Anti-Hepatitis C Activity

[0347] Compounds can exhibit anti-hepatitis C activity by inhibiting HCV polymerase, by inhibiting other enzymes needed in the replication cycle, or by other pathways. A number of assays have been published to assess these activities. A general method that assesses the gross increase of HCV virus in culture is disclosed in U.S. Patent No. 5,738,985 to Miles et al In vitro assays have been reported in Ferrari et al JnI ofVir., 73:1649-1654, 1999; Ishii et al, Hepatology, 29:1227-1235, 1999; Lohmann et al, JnI of Bio. Chem., 274:10807- 10815, 1999; and Yamashita et al, JnI of Bio. Chem., 273:15479-15486, 1998. [0348] WO 97/12033, filed on September 27, 1996, by Emory University, listing C. Hagedorn and A. Reinoldus as inventors, which claims priority to United States Provisional Patent Application.Serial No. 60/004,383, filed on September 1995, describes an HCV polymerase assay that can be used to evaluate the activity of the compounds described herein. Another HCV polymerase assay has been reported by Bartholomeusz, et al, Hepatitis C Virus (HCV) RNA polymerase assay using cloned HCV non-structural proteins; Antiviral Therapy 1996:l(Supp 4) 18-24.

[0349] Screens that measure reductions in kinase activity from HCV drugs are disclosed in U.S. Patent No. 6,030,785, to Katze et al, U.S. Patent No. 6,228,576, Delvecchio, and U.S. Patent No. 5,759,795 to Jubin et al Screens that measure the protease inhibiting activity of proposed HCV drugs are disclosed in U.S. Patent No. 5,861,267 to Su et al, U.S. Patent No. 5,739,002 to De Francesco et al, and U.S. Patent No. 5,597,691 to Houghton et al

Example 2. Replicon Assay

[0350] A cell line, ET (Huh-lucubineo-ET) is used for screening of compounds of the present embodiments for HCV RNA dependent RNA polymerase. The ET cell line is stably transfected with RNA transcripts harboring a I₃8₉luc-ubi- neo/NS3-37ET; replicon with firefly luciferase-ubiquitin-neomycin phosphotransferase fusion protein and EMCV-IRES driven NS3-5B polyprotein containing the cell culture adaptive mutations (E1202G; T1280I; Kl 846T) (Krieger at al, 2001 and unpublished). The ET cells are grown in DMEM, supplemented with 10% fetal calf serum, 2 mM Glutamine, Penicillin (100 IU/mL)/Streptomycin (100 μg/mL), Ix nonessential amino acids, and 250 μg/mL G418 ("Geneticin"). They are all available through Life Technologies (Bethesda, MD). The cells are plated at 0.5-1.0 xlO⁴ cells/well in the 96 well plates and incubated for 24 hrs before adding nucleoside analogs. Then the compounds were added to the cells to achieve a final concentration of 50 or 100 μM, or whatever concentration is desired. For these determinations, 6 dilutions of each compound are used. Compounds are typically diluted 3 fold to span a concentration range of 250 fold. Luciferase activity will be measured 48-72 hours later by adding a lysis buffer and the substrate (Catalog number Glo-lysis buffer E2661 and Bright-Glo leuciferase system E2620 Promega, Madison, WI). Cells should not be too confluent during the assay. Percent inhibition of replication will be plotted relative to no compound control. Under the same condition, cytotoxicity of the compounds will be determined using cell proliferation reagent, WST-I (Roche, Germany). IC₅₀ and TC₅₀ values are calculated by fitting %inhibition at each concentration to the following equation, where b is Hill's coefficient:

% Inhibition = 100%/[(IC50/[l])^b +1]

Example 3. Cloning and expression of recombinant HCV-NS 5b

[0351] The coding sequence of NS 5b protein is cloned by PCR from pFKI₃₈₉luc/NS3-3'/ET as described by Lohmann, V., et al. (1999) Science 285,

110-113 using the primers shown on page 266 of WO 2005/012288, herein incorporated by reference in its entirety.

[0352] The cloned fragment is missing the C terminus 21 amino acid residues.

The cloned fragment is inserted into an IPTG-inducible expression plasmid that provides an epitope tag (His)6 at the carboxy terminus of the protein.

[0353] The recombinant enzyme is expressed in XL-I cells and after induction of expression, the protein is purified using affinity chromatography on a nickel-

NTA column. Storage condition is 10 mM Tris-HCl pH 7.5, 50 niM NaCl, 0.1 mM EDTA, 1 mM DTT, 20% glycerol at -20 °C.

Example 4. HCV-NS5b Enzyme Assay [0354] The polymerase activity is assayed by measuring incorporation of radiolabeled UTP into a RNA product using a biotinylated, heteropolymeric template, which includes a portion of the HCV genome. Typically, the assay mixture (50 μL) contains 10 mM Tris-HCl (pH 7.5), 5 mM MgCl₂, 0.2 mM EDTA, 10 mM KCl, 1 unit/μL RNAsin, 1 mM DTT, 10 μM each of NTP, including [³H]-UTP, and 10 ng/μL heteropolynieric template. Test compounds are initially dissolved in 100% DMSO and farther diluted in aqueous buffer containing 5% DMSO. Typically, compounds are tested at concentrations between 1 nM and 100 μM. Reactions are started with addition of enzyme and allowed to continue at 37°C for 2 hours. Reactions are quenched with 8 μL of 100 mM EDTA and reaction mixtures (30 μL) are transferred to streptavidin- coated scintillation proximity microtiter plates (FlashPlates) and incubated at 4°C overnight. Incorporation of radioactivity is determined by scintillation counting.

Formulation Examples

[0355] The following are representative pharmaceutical formulations containing a compound of the present embodiments.

Example 1: Tablet formulation

[0356] The following ingredients are mixed intimately and pressed into single scored tablets.

Quantity per

Ingredient tablet, mg compound of the embodiments 400 cornstarch 50 croscarmellose sodium 25 lactose 120 magnesium stearate 5

Example 2: Capsule formulation [0357] The following ingredients are mixed intimately and loaded into a hard-shell gelatin capsule.

Quantity per

Ingredient ^ capsule, mg compound of the embodiments 200 lactose, spray-dried 148 magnesium stearate 2 Example 3: Suspension formulation

[0358] The following ingredients are mixed to form a suspension for oral administration.

Example 4: Injectable formulation

[0359] The following ingredients are mixed to form an injectable formulation.

Example 5: Suppository formulation

[0360] A suppository of total weight 2.5 g is prepared by mixing the compound of the embodiments with Witepsol® H- 15 (triglycerides of saturated vegetable fatty acid; Riches-Nelson, Inc., New York), and has the following composition:

[0361] One skilled in the art will recognize that the above Examples are for exemplification only and should in no way limit the scope of the invention. Modifications of the compositions and methods described herein or referred to, herein, will be apparent to one skilled in the art, without departing from the scope of the invention.

Claims

WHAT IS CLAIMED IS:

1. A compound of Formula I:

wherein

Y is selected from the group consisting of a bond, -CH₂- or -O-; each of A⁰ is independently selected from A¹, A² or W³ with the proviso that the compound of Formula I includes at least one A¹; A¹ Is:

A² is:

Y² is independently a bond, O, N(R^x), N(O)(R^x), N(OR*), N(O)(OR"), N(N(R^x)( R^x)), -S(O)_m2-, or -S(O)_m2-S(O)_m2-;

R² is independently H, R¹, R³ or R⁴ wherein each R⁴ is independently substituted with O to 3 R groups, or taken together at a carbon atom, two R groups form a ring of 3 to 8 carbons and the ring may be substituted with O to 3 R³ groups;

W⁶ is W³ independently substituted with 1, 2, or 3 A³ groups; A³ is:

Y¹ is independently O, S, N(R^x), N(O)(R^x), N(OR^x), N(O)(OR^x), or N(N(R^x)(

R^x));

W³ is W⁴ or W⁵;

W⁴ is R⁵, -C(Y¹)R⁵, -C(Y¹)W⁵, -SO₂R⁵, or -SO₂W⁵;

W is carbocycle or heterocycle wherein W⁵ is independently substituted with 0 to 3 R² groups;

R⁵ is R⁴ wherein each R⁴ is substituted with 0 to 3 R³ groups;

R⁴ is an alkyl of 1 to 18 carbon atoms, alkenyl of 2 to 18 carbon atoms, or alkynyl of 2 to 18 carbon atoms;

R^x is independently H, R¹, W³, a protecting group, or the formula:

R¹ is independently H or an alkyl of 1 to 18 carbon atoms;

R^y is independently H, W³, R² or a protecting group;

R³ is R^3a, R^3b, R^3c or R^3d, provided that when R³ is bonded to a heteroatom, then R³ is R^3c or R^3d;

R^3a is F, Cl, Br, I, -CN, N₃ or -NO₂;

R^3b is Y¹;

R^3c is -R^x, -N(R^x)(R^x), -SR^x, -S(O)R^x, -S(O)₂R^x, -S(O)(OR^x), -S(O)₂(OR^x), -OC(Y¹)R^x -OC(Y¹)OR^x, -OC(Y¹)N(R^x)(R^x) ), -SC(Y¹)R^x, -SC(Y¹)OR^x, -SC(Y¹)(N(R^x)(R^x)), -N(R^x)C(Y¹)R^x, -N(R^x)C(Y¹)OR^x, or -N(R^x)C(Y¹)(N (R^x)) ;

R^3d is -C(Y¹)R^x, -C(Y¹)OR^x or -C(Y¹) (N(R^x)(R^x)); ml a, ml c, and mid are independently O or 1; m2 is 0, 1 or 2; ml 2a is 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; ml 2b is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; ml 2c is 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12; and

T is selected from the group consisting of a) -C≡C-Z, where Z is selected from the group consisting of i) tri(Ci-C₄)alkylsilyl. -C(O)NZ¹Z², alkoxyalkyl, lieteroaryl, and substituted heteroaryl, and phenyl substituted with 1 to 3 substituents selected from the group consisting of alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, aminoacyl, amidino, amino, substituted amino, carboxyl, carboxyl ester, cyano, cycloalkyl, substituted cycloalkyl, cycloalkoxy, substituted cycloalkoxy, guanidino, halo, heteroaryl, substituted heteroaryl, hydrazino, hydroxyl, nitro, thiol, and -S(O)_mZ ; wherein Z¹ and Z² are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, amino, substituted amino, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic provided that only one of Z and Z is amino or substituted amino, and further wherein Z¹ and Z², together with the nitrogen atom pendant thereto, form a heterocyclic or substituted heterocyclic;

Z³ is selected from the group consisting of alkyl, substituted alkyl, amino, substituted amino, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic; and m is an integer equal to 0, 1 or 2; ii) -C(O)OZ¹⁴ , where Z¹⁴ is hydrogen, alkyl or substituted alkyl; b) -CH=CH-Q², where Q² is selected from hydrogen or cis-methoxy; c) -C(O)H; d) -CH=NNHZ¹⁵, where Z¹⁵ is H or alkyl; e) -CH=N(OZ¹⁵), where Z¹⁵ is as defined above; f) -CH(OZ¹⁶)₂, where Z¹⁶ is (C₃ - C₆)alkyl; g) -B(OZ¹⁵)₂, where Z¹⁵ is as defined above; and h) -NO₂; and pharmaceutically acceptable salts or partial salts thereof; wherein A⁰ is a prodrug moiety; provided that the prodrug moiety is not selected from the group consisting of acyl, oxyacyl, phosphonate, phosphate esters, phosphate, phosphonamidate, phosphorodiamidate, phosphor amidate monoester, cyclic phosphoramidate, cyclic phosphorodiamidate, phosphoramidate diester, and -C(O)CHR^fNH₂, a prodrug of the formula:

a prodrug of the formula:

wherein R^e is selected from the group consisting of alkyl, substutituted alkyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclic and substituted heterocyclic;

R^f is selected from the group consisiting of hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted hetereoaryl, heterocyclic, substituted heterocyclic, and a sidechain of an amino acid; and

R^g is hydrogen or alkyl.

2. A compound according to Claim 1, wherein T is -C≡C-Z and Z is selected from the group consisting of tri(Ci-C4)alkylsilyl, -C(O)NZ¹Z², alkoxyalkyl, heteroaryl, substituted heteroaryl, phenyl and phenyl substituted with 1 to 3 substituents, wherein the 1-3 substituents are selected from the group consisting of alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, acyl, acylamino, acyloxy, aminoacyl, amidino, amino, substituted amino, carboxyl, carboxyl ester, cyano, cycloalkyl, substituted cycloalkyl, cycloalkoxy, substituted cycloalkoxy, guanidino, halo, heteroaryl, substituted heteroaryl, hydrazino, hydroxyl, nitro, thiol, and -S(O)_mZ³; wherein R¹ and R² are independently selected from the group consisting of hydrogen, alkyl, substituted alkyl, amino, substituted amino, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic provided that only one of Z and Z² is amino or substituted amino, and further wherein Z¹ and Z², together with the nitrogen atom pendant thereto, form a heterocyclic or substituted heterocyclic;

Z³ is selected from the group consisting of alkyl, substituted alkyl, amino, substituted amino, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic; and m is an integer equal to 0, 1 or 2; or a pharmaceutically acceptable salt thereof.

3. The compound according to Claim 2, wherein Z is selected from the group consisting of -C(O)NH₂, -Si(CH₃)₃, pyrid-2-yl, 4-methoxyphenyl, and - CH(OCH₂CH₃)₂.

4. The compound according to Claim 1, wherein T is -C≡C-Z, Z is -C(O)OZ¹⁴, and Z¹⁴ is H or alkyl.

5. The compound according to Claim 4, wherein Z is methyl or ethyl.

6. The compound according to Claim 1, wherein T is -CH=CH-Q², wherein Q² is selected from hydrogen or cis-methoxy.

7. The compound according to Claim 1, wherein T is -C(=O)H.

8. The compound according to Claim 1, wherein T is -CH=NNHZ¹⁵ wherein Z¹⁵ is independently selected from the group consisting of hydrogen and alkyl.

9. The compound according to Claim 1, wherein T is -CH=N(OZ¹⁵) wherein Z¹⁵ is independently selected from the group consisting of hydrogen and alkyl.

10. The compound according to Claim I, wherein T is -CH(OZ¹⁶)₂ wherein Z ,1¹6⁰ is independently (C₃-C₆)alkyl.

11. The compound according to Claim 1 , wherein T is -B(OZ¹⁵)₂, wherein Z¹⁵ is independently selected from the group consisting of hydrogen and alkyl.

12. The compound of any one of Claims 1 to 11, wherein A¹ is of the formula:

13. The compound of Claim 12, wherein A¹ is of the formula:

14. The compound of Claim 13, wherein A¹ is of the formula:

15. The compound of Claim 14, wherein A¹ is of the formula:

wherein W^5a is a carbocycle independently substituted with 0 or 1 R² groups.

16. The compound of Claim 15, wherein ml 2a is 1.

17. The compound of any one of Claims 1 to 11, wherein A³ is of the formula:

18. The compound of Claim 17, wherein A³ is of the formula:

19. The compound of Claim 18, wherein A³ is of the formula:

wherein Y^1a is O or S; and Y^2a . is O, N(R^x) or S.

20. The compound of Claim 19, wherein A³ is of the formula:

wherein Y^2b is O orN(R^x).

21. The compound of Claim 20, wherein A is of the formula:

22. The compound of Claim 20, wherein A³ is of the formula:

wherein ml 2d is 1, 2, 3, 4, 5, 6, 7 or 8.

23. The compound of Claim 22, wherein A³ is of the formula:

24. The compound of Claim 23, wherein ml2d is 1.

25. The compound of any one of Claims 1 to 11, wherein A³ is of the formula:

26. The compound of Claim 25, wherein A³ is of the formula:

27. The compound of Claim 26, wherein W⁵ is a carbocycle.

28. The compound of Claim 27, wherein A³ is of the formula:

29. The compound of Claim 28, wherein W⁵ is phenyl.

30. The compound of Claim 25, wherein ml 2b is 1.

31. The compound of Claim 30, wherein A³ is of the formula:

wherein Y^la is O or S; and Y^2a is O, N(R^x) or S.

32. The compound of Claim 31 , wherein A³ is of the formula:

wherein Y²Ms O or N(R^x).

33. The compound of Claim 32, wherein A³ is of the formula:

wherein ml 2d is 1, 2, 3, 4, 5, 6, 7 or 8.

34. The compound of Claim 33, wherein R¹ is H.

35. The compound of Claim 33 , wherein ml 2 d is 1.

36. The compound of Claim 33, wherein A³ is of the formula:

37. The compound of Claim 36, wherein A³ is of the formula:

38. The compound of Claim 37, wherein A³ is of the formula:

39. The compound of any one of Claims 1 to 11, wherein R^x is of the formula:

40. The compound of Claim 39, wherein R^x is of the formula:

wherein Y^la is O or S; and Y^2c is O, N(R^y) or S.

41. The compound of Claim 40, wherein R^x is of the formula:

wherein Y^la is O or S; and Y^2d is O or N(R^y).

42. The compound of Claim 41 , wherein R^x is of the formula:

43. The compound of Claim 42, wherein R^x is of the formula:

44. The compound of any one of Claims 1 to 11 , wherein R^x is of the formula:

45. The compound of Claim 44, wherein A³ is of the formula:

46. The compound of any one of Claims 1 to 11, wherein A is of the formula:

and

R^x is of the formula:

47. The compound of Claim 46, wherein A³ is of the formula:

wherein Y^la is O or S; and Y^2a is O₃ N(R²) or S.

48. The compound of Claim 47, wherein A³ is of the formula:

Y^2b is O or N(R²); and Y^2c is O, N(R^y) or S.

49. The compound of Claim 48, wherein A³ is of the formula:

wherein Y^2d is O or N(R^y); and ml2d is 1, 2, 3, 4, 5, 6, 7 or 8.

50. The compound of Claim 49, wherein A³ is of the formula:

51. The compound of Claim 50, wherein A³ is of the formula:

52. The compound of Claim 51 , wherein A³ is of the formula:

53. The compound of any one of Claims 1 to 11 , wherein A is of the formula:

R^x is of the formula:

54. The compound of Claim 53, wherein A is of the formula:

wherein Y^la is O or S; and Y^2a is O, N(R²) or S.

55. The compound of Claim 54, wherein A is of the formula:

wherein Y^2b is O or N(R²); and Y^2c is O, N(R^y) or S.

56. The compound of Claim 55, wherein A is of the. formula:

wherein Y^2d is O or N(R^y); and ml2d is I, 2, 3, 4, 5, 6, 7 or 8.

57. The compound of Claim 56, wherein A³ is of the formula:

58. The compound of Claim 57, wherein A³ is of the formula:

59. The compound of any one of Claims 1 to 11, wherein A is of the formula:

A , 3 is of the formula:

60. The compound of Claim 59, wherein A¹ is of the formula:

A is of the formula:

and

R^x is of the formula:

61. The compound of Claim 60, wherein A¹ is of the formula:

A is of the formula:

wherein Y^ia is O or S; and Y^/a is O, N(R^Z) or S,

62. The compound of Claim 61, wherein A is of the formula:

wherein W^5a is a carbocycle independently substituted with 0 or 1 R² groups; and A³ is of the formula:

63. The compound of Claim 62, wherein A¹ is of the formula:

A³ is of the fonnula:

wherein Y^2d is O or N(R^y); and ml2d is 1, 2, 3, 4, 5, 6, 7 or 8.

64. The compound of Claim 63, wherein A¹ is of the formula:

65. The compound of Claim 63, wherein A¹ is of the formula:

66. The compound of any one of Claims 1 to 11, wherein A¹ is of the formula:

A is of the formula:

67. The compound of Claim 66, wherein A¹ is of the formula:

A³ is of the formula:

R^x is of the formula:

68. The compound of Claim 67, wherein A¹ is of the formula:

A³ is of the formula:

wherein Y^la is O or S; and Y^2a is O, N(R²) or S.

69. The compound of Claim 68, wherein A¹ is of the formula:

W^3a is a carbocycle independently substituted with 0 or 1 R^z groups; A³ is of the formula:

wherein Y^2b is O or N(R²); and Y^2c is O, N(R^y) or S.

70. The compound of Claim 69, wherein A³ is of the formula:

71. The compound of Claim70, wherein A¹ is of the formula:

wherein W^5a is a carbocycle or heterocycle substituted with 0 or 1 R² groups; and A³ is of the formula:

and further wherein Y^la is O or S; Y^2b is O or N(R²); Y^2d is O or N(R^y); and mlld x^'s 1, 2, 3, 4, 5, 6, 7 or 8.

72. The compound of Claim 7I, wherein Y •2²b⁰ is O and W is phenyl.

73. The compound of Claim 72, wherein A is of the formula:

74. The compound of Claim 71 , wherein A is of the formula:

75. The compound of Claim 71, wherein A¹ is of the formula:

•

76. The compound of any one of Claims 1 to 11, wherein A² is of the formula:

77. The compound of Claim 76, wherein A² is of the formula:

78. THe compound of Claim 77, wherein ml 2b is 1.

79. The compound of Claim 77, where ml 2b is 0; Y² is a bond and W⁵ is W^5b wherein W^5b is a carbocycle or heterocycle optionally substituted with 1, 2, or 3 R² groups.

80. The compound of Claim 77, wherein A² is of the formula:

and W⁵ is a carbocycle or heterocycle where W^5a is optionally and independently substituted with 1, 2, or 3 R groups.

81. The compound of Claim 80, wherein ml 2a is 1.

82. The compound of Claim 80, wherein A² is selected from the group consisting of phenyl, substituted phenyl, benzyl, substituted benzyl, pyridyl, and substituted pyridyl.

83. The compound of any one of Claims 1 to 11 , wherein A is of the formula:

84. The compound of Claim 83, wherein A² is of the formula:

85. The compound of Claim 84, wherein ml 2b is 1.

86. A pharmaceutical composition comprising a pharmaceutically acceptable diluent and a therapeutically effective amount of a compound or a mixture of one or more of such compounds of Claim 1-85.

87. The pharmaceutical composition according to Claim 86, wherein said composition further comprises a therapeutically effective amount of one or more agents active against HCV.

88. The pharmaceutical composition according to Claim 87, wherein said one or more agents is/are selected from the group consisting of ribavirin, levovirin, thymosin alpha-1, an inhibitor of NS3 serine protease, inhibitor of inosine monophosphate dehydrogenase, interferon-alpha, and pegylated interferon-alpha, either alone or in combination with ribavirin, or levovirin.

89. The pharmaceutical composition according to Claim 88, wherein said one or more agents is/are interferon-alpha or pegylated interferon-alpha alone or in combination with ribavirin, or levovirin.

90. A method for treating and/or inhibiting a viral infection in a mammal which infection is mediated at least in part by a virus in the flaviviridae family of viruses which method comprise administering to said mammal, that has been diagnosed with said viral infection or is at risk of developing said viral infection, a pharmaceutical composition according to Claim 86.

91. The method according to Claim 90 wherein said virus is hepatitis C virus.

92. The method according to Claim 91 wherein said pharmaceutical composition further comprises a therapeutically effective amount of one or more agents active against HCV.

93. The method according to Claim 92 wherein said one or more agents is/are selected from the group consisting of ribavirin, levovirin, viramidine, thymosin alpha- 1, an inhibitor of NS3 serine protease, inhibitor of inosine monophosphate dehydrogenase, interferon-alpha, and pegylated interferon-alpha, alone or in combination with ribavirin or levovirin.

94. The method according to Claim 93 wherein said one or more agents is/are interferon-alpha or pegylated interferon-alpha alone or in combination with ribavirin or levovirin.

95. A use of a compound according to any of Claims 1-85 in the manufacture of a medicament for treating and/or inhibiting a viral infection in a mammal which infection is mediated at least in part by a virus in the flaviviridae family of viruses.

96. The use according to Claim 95 wherein said virus is hepatitis C virus.

97. The use according to Claim 95 wherein said pharmaceutical composition further comprises a therapeutically effective amount of one or more agents active against HCV.

98. The use according to Claim 97 wherein said one or more agents is/are selected from the group consisting of ribavirin, levovirin, viramidine, thymosin alpha- 1, an inhibitor of NS3 serine protease, inhibitor of inosine monophosphate dehydrogenase, interferon-alpha, and pegylated interferon-alpha, alone or in combination with ribavirin or levovirin.

99. The use according to Claim 98 wherein said one or more agents is/are interferon-alpha or pegylated interferon-alpha alone or in combination with ribavirin or levovirin.