WO2014207212A1

WO2014207212A1 - Connecting piece for closed, drip-free and secure transfer of fluids

Info

Publication number: WO2014207212A1
Application number: PCT/EP2014/063721
Authority: WO
Inventors: Max Bichlmaier; Andreas Eursch; Oliver BUCH; Tuomo Nikula; Siegfried FÖRG
Original assignee: Gbn Systems Gmbh
Priority date: 2013-06-28
Filing date: 2014-06-27
Publication date: 2014-12-31

Abstract

The invention relates to a connecting piece for drip-free and secure transfer of fluids, comprising a sealing device for sealing the connecting piece, and a cannula arranged in the connecting piece, wherein the cannula and the sealing device are moveable relative to one another between two positions. In a first position, the cannula penetrates the sealing device such that the tip of the cannula protrudes out of the sealing device, and in a second position the cannula is withdrawn behind the sealing device. The connecting piece is configured in such a way that it can be coupled to a further corresponding connecting piece to create a drip-free and secure connection system, and the cannula has a closed tip and an opening that is offset from the tip.

Description

Connector for sealed, drip-free and safe transfer of fluids

The invention relates to a connector suitable for use in the medical field for the closed, drip-free and secure transfer of fluids, and a device comprising two connectors, in which leakage and contamination of a fluid is prevented both with interconnected connectors and after the connection pieces have been disconnected can be.

In the manufacture and administration of medicaments, parent substances and manufactured medicaments must be transferred between various devices, such as containers, dosing and mixing devices, and devices for administration, such as syringes or catheters. If the substances pose a health risk to the people around them, contact or contamination must always be avoided. This applies in particular to hazardous substances, including acids and radioactive substances, such as radioactive isotope-labeled drugs or compounds, whose production, due to their temporal variability, can occur only near the site of administration and relatively quickly before administration.

On the other hand, in order to ensure a high product quality, it is necessary to avoid contamination of medicines and the starting substances in the preparation and also after the production, such as in the transfer to facilities for dosing, storage and administration, as well as in the administration itself.

Various devices are known in the prior art, which are used in the manual, semi-automatic or fully automated production for transfer, dosing, mixing and administering, inter alia, hazardous drugs, especially toxic or radioactive substances containing compounds or compounds. For example, so-called luer locks are used to connect open hoses or hoses, catheters or needles, which can optionally be locked with an additional stopcock or lid. Although hoses provided with luer-lock components can be bolted together or with catheters, needles, etc., so that a tight connection can be made and inadvertent release can be precluded Disadvantage that when separating the interconnected components drops and people come into contact with it, which involves risks with hazardous substances. Also, it may come to contamination of the substances from the outside.

Furthermore, the use of a septum and a needle for metering and transferring substances is known in the art. The disadvantage, however, is that the piercing of the needle into the septum can trigger an overpressure and a drop formation and that after removal of the needle from a container provided with the septum optionally drops escape from the needle and can come into contact with persons. Furthermore, there is a risk of injury due to the usually sharp tip of the needle.

As a common connection between hoses for the transfer of primarily gaseous fluids further couplings are known, which open automatically when inserting a counterpart and close automatically when removing the counterpart. However, usually only the pressurized side is closed and there is no protection against dripping. In addition, contamination by contact with the outside of the separate hose or pipe sections is possible.

The said devices also provide some protection against contamination of the substances handled thereby, which is insufficient to ensure high product quality.

Furthermore, in the prior art EP2012868 A a connection piece for the closed, drip-free and secure transfer of fluids is known, which has an opening and a closure device for closing the opening and for producing a sealed connection with another connection piece for the transfer of a fluid is arranged between the connecting pieces, wherein the connecting piece inside a displaceable needle holder provided with a line section, so that the line section can be advanced through the opening of the connector, with a pawl which is pivotally mounted about an axis and by means of a spring in a the forward movement of the needle holder locking position is held, so that advancement of the needle holder is prevented when the connector of the further is separated, while pivoting the pawl against the bias of the spring when mating with the other connector, the pawl can be disengaged from the needle holder.

It is the object of the present invention to provide a connector for transferring fluids, with which contamination of the outer surfaces of the connector or the environment and in particular of persons by a fluid which is supplied into the connector or transferred to a further connector coupled thereto, both during the period of fluid communication of the fitting with a complementary fitting and during or after the separation of the fluid connection can be avoided.

This object is achieved by a connecting piece with the features according to claim 1, a connecting device having the features according to claim 31 and a corresponding method having the features according to claim 38. Preferred embodiments of the invention are specified in the subclaims.

According to the invention, there is provided a fitting for closed, drip-free and secure transfer of fluids comprising a closure means closing the fitting and a cannula disposed in the fitting, the cannula and closure means being movable relative to each other between two positions, wherein in a first Position the cannula penetrates the closure device, so that the tip of the cannula protrudes from the closure device, and in a second position, the cannula is withdrawn behind the closure device, wherein the connection piece is configured so that it with a corresponding further connection piece for producing a drip-free and secure connection device can be coupled.

The fluids may in particular be dangerous, radioactive or harmful gases or liquids. The liquids or gases may be of any kind and include any chemical or pharmaceutical or medicinal substances. With the connecting piece according to the invention, a drip-proof and stable connection between fluid lines can be provided in connection with a corresponding further fitting piece fitting together, wherein no drops remain on open surfaces of the connecting pieces, in particular the closing device, in particular during the separation process of the connecting pieces. The avoidance of drops on the open surfaces of the fittings is, in one embodiment, ensured in particular by an opening offset from the tip of the cannula, which prevents a drop from remaining on an open surface, in particular at the closure means, since the opening of the cannula is already behind Closure device of the connector is withdrawn when the tip of the cannula is pulled out of the closure device, which may result in an open-ended cannula for the retention of a fluid residue on the closure device.

The fitting may be used with a variety of fluids, particularly liquids or gases. The dimensions of the cannula and the conduit are chosen according to the intended flow rates. Accordingly, the dimensions of the remaining components of the fitting are determined. The cannula may for example have a diameter of 0.1 mm, 0.25 mm, 0.5 mm, 1 mm, 2.5 mm, 5 mm, 1 cm, 2.5 cm, 5 cm or a value in the range between the indicated values.

In addition, the closure means is disposed on the fitting and the fitting is sealed so that in a position in which the cannula is withdrawn behind the closure means of the fitting in which it is disposed, no drops of the fluid from the cannula or generally from the interior of the connector to the outside can escape.

According to one embodiment, the closure device comprises a platelet, a membrane or a septum made of a material which can be penetrated by the cannula and automatically closes again after retraction of the cannula.

The platelet, membrane or septum may be formed of a material suitable for a closure device which will provide the desired seal and preferably have the property of having repeated puncturing Close tightly with a cannula and then retract. Suitable materials are elastomers, such as rubber, rubber, silicone, elastic plastics including Teflon. The tightness can be ensured even after a repeated puncture with a cannula at pressures of several bar, in particular 1, 3, 5, and up to 7 bar in the cannula, without drops of fluid from the cannula reach the outside of the closure device of the connector can, in which it is arranged. The tightness of the closure device depends, among other things, on its length. A suitable closure means may comprise a platelet, a membrane or a septum having a length of 0.5 mm to 4 mm or more and preferably of a length of between 1 and 3 mm.

According to a further embodiment, the closure device in the connection piece in a radial direction with respect to a direction of passage of the cannula through the closure device is at least partially pressurized and compressed over its circumference.

The closure device may have the shape of a round or angular disk whose diameter is slightly larger than a correspondingly shaped round or angular receptacle or holder in the connecting piece and thus has an oversize, so that exerted on the closure device in the installed state in the connector, a radial pressure which compresses the material of the closure device, whereby the tightness of the closure device, in particular at the points which are pierced with the cannula (in particular the central region), is increased. The diameter of the closure device in the uncompressed state may be 5%, 10%, 20%, 50%> or even 100% larger than the inner diameter of the corresponding receptacle in the fitting. Preferably, the excess is between 5% and 15%. The receptacle may be a part of the connector and be formed in one piece with this. A radial pressure can also be exerted by the inclusion on the closure device.

According to another embodiment, the closure device has a convex surface facing the outside of the connection piece, through which the cannula emerges from the closure device. The convex surface directed towards the outside of the connection piece has the advantage that when the closure device is separated from a corresponding plane or also convex surface of a closure device of a further connection piece to which the connection piece is coupled, the formation of a negative pressure between the closure devices due to mutual adherence the closure means or due to the retraction of the cannula tip is avoided, which may otherwise result in retention of a fluid residue and dripping on the outside of the closure device during retraction of the cannula result. The convex surface may be caused by the radial compression of the material of the closure device when inserted into a corresponding receptacle with a smaller inner diameter than the outer diameter of the closure device, or the closure device may be provided with a convex surface without radial compression during its manufacture.

According to another embodiment, the closure device can also be formed by a mechanical closure device, which works on the principle of a central closure or focal plane shutter.

According to yet another embodiment, the connector comprises a housing surrounding at least a portion of the cannula, at the proximal end of which the closure device is disposed, the housing being movably disposed in the fitting and configured to pivot between a first position in which the Retracted tip of the cannula of the closure device is located inside the housing, and a second position in which the cannula penetrates the closure device and protrudes outwardly from the housing, can be moved.

The housing may have an elongated elongated shape with a square, in particular square cross section, a round shape with a circular cross section or any other suitable shape, which may correspond at least in some places on the inside and the inside diameter of a corresponding receptacle in the connector, so that Housing is at least partially positively received in the receptacle and at least partially held and guided by the inner walls of the receptacle of the connector. An opening for the exit of the cannula from the housing may be provided at the rear of the housing inside the connector, wherein the opening and the housing may be sealed relative to the cannula, so that no substances that possibly escape from the cannula can pass from the housing into the interior of the connection piece or to the outside of the connection piece.

According to a further embodiment, the tip of the cannula has a radially symmetrical shape and is closed. A cannula of radially symmetrical shape has the advantage of damaging the occlusion device less or not at all when penetrating compared to other shapes of tips, in particular ground tips, so that the closure device retains its tightness even after a large number of punctures of cannulas. An advantage of a symmetrical cannula is also that it centers centrally through the closure device. On the other hand, a cannula with a lateral cut tends to laterally offset because it follows the cut as it passes through the septum.

A tip-closed cannula with a lateral opening also has the advantage that when the cannula is withdrawn by the closure device, no fluid droplets escape from the tip and are stripped off the closure device, which is the case with cannulas having an opening at the tip can be and can be attributed to a negative pressure between two adjoining closure devices, which arises in particular when retracting the tip of the closure means and causes the outside of the closure device is contaminated. In the case of a side-opening cannula, as the needle tip exits the occlusion device, it is behind the obturator so that the outside can not be contaminated when the cannula tip is withdrawn from the obturator. The opening in the cannula is located a distance from the tip of the cannula which corresponds at least to the length of the closure means. However, the distance may be greater, for example 3, 4, 5 mm, 1 cm or 2 cm or more.

In yet another embodiment, the fitting includes a conduit connected to the cannula and a control device for controlling a flow of fluid through the conduit.

With the aid of the control device, a flow of a fluid through the line can be permitted or blocked. Preferably, the control device is configured and coupled to a locking device on the connector that the flow of a fluid through the line is only allowed, ie the control device is at least partially open when the cannula is advanced through both locking devices of the coupled connectors and connected to the line in the other connector and then the locking device has been opened.

According to yet another embodiment, the control device is movably mounted on the fitting and may be displaced between two or more positions, wherein in a first position the flow of fluid through the conduit is permitted, in a second position the flow of the fluid through the conduit is blocked and in a third position blocks the flow of fluid through the conduit and increases the volume of the conduit between the cannula and the position of the regulator along the conduit relative to the second position.

According to one embodiment, the control device is arranged on the connection piece so that it can be displaced in a position blocking the flow through the line along the line, so that the volume in the line between the position of the control device on the line and one end of the line in Connection piece is enlarged or reduced.

Increasing the volume in the conduit between the cannula and the position of the control device on the conduit in the connector can cause when the flow through the cannula or conduit in the other connector to which the connector is coupled and with its cannula or conduit Cannula or line of the connector is also locked, that in the line and the connected cannula, a negative pressure is generated, which prevents a fluid, which is located in the conduit or cannula, can escape from the cannula. The generation of the negative pressure is particularly important before retraction of the cannula by the locking means of the coupled fittings, since, especially during retraction of the cannula by the closure means, droplets of fluid can escape from the cannula and be retained at the closure means, so that the exterior get the connection piece. According to yet another embodiment, the control device comprises a bolt whose ends are received in guides in the connector and whose position relative to the line can be changed and can be brought by moving in the first, second or third position that the inner cross section by squeezing the line varies and thus the flow through the line can be controlled. The control device according to this embodiment is particularly suitable in connection with flexible lines, in which the line cross-section can be reduced or varied by squeezing.

The bolt may in particular be provided with a roller about its axis, which is brought into contact with the conduit and with which the diameter of the conduit can be varied. The roller allows the pin to slide along the line, with the roller unwinding on the line while reducing or preventing flow through the line.

In yet another embodiment, the fitting is movably disposed in an outer housing, the fitting moving between a first position in which the fitting is substantially inserted into the outer housing and a second position in which the fitting is advanced out of the outer housing can be, and the connector comprises at least a portion of a locking device which is configured so that the movement of the connector from the second position to the first position is permitted only when the locking device is unlocked, and is otherwise locked. The outer housing may be formed as a handle for the connector or also form part of a device in which the connector is integrated or installed.

In another embodiment, the control device is coupled to the outer housing and may be actuated by moving the fitting relative to the outer housing. This relative movement can be controlled by the locking device described above, in particular locked or released.

The control device may in particular be coupled to the outer housing in such a way that it passes through the connection piece and on both sides of the connection piece on External housing is attached or stored. It is also conceivable to provide guides in the outer housing, in which the ends of the control device projecting from the connecting piece are guided, wherein the guides are designed such that they move the control device perpendicular to the direction of extension of the line and perpendicular to the relative direction of movement between the connecting piece and allow the outer housing.

According to one embodiment, the fitting may include a control device or shut-off device for controlling the flow through the cannula or conduit that includes or is a valve, such as a check valve, a two-way or three-way valve or other valve.

According to a further embodiment, the connecting piece has a device for generating a negative pressure in the cannula and / or in the conduit. The device may have a body connected to the cannula or the conduit, the volume of which can be increased to produce the negative pressure. The device is preferably used to generate a negative pressure in the cannula or the conduit, so that the risk of leakage of a fluid from the cannula is avoided, in particular when disconnecting the connector from a further connector coupled thereto. For example, the device for generating a negative pressure in the cannula and / or in the conduit could be formed by a membrane or a septum or have a membrane or a septum. The device for generating a negative pressure may also be a pump.

In yet another embodiment, the fitting includes at least a portion of a locking device that is configured so that relative movement between the locking device and the cannula is permitted only when the locking device is unlocked and otherwise locked. The locking device can also be arranged on the movable housing of the connection piece or on the outer housing and block or unlock a relative movement between the housing and the cannula or the connection piece.

The locking device prevents the closure device, when the connector or the housing is not coupled with another connector, but separated therefrom, is pushed back over the cannula, so that the tip of the cannula from the closure device and thus protrudes from the connector, which entails the risk of leakage of fluid from the cannula or injury to persons through the tip.

The locking device may be adapted to be unlocked by another fitting or a corresponding element formed thereon, such as a nose or protrusion, upon assembly of the fittings, for example by inserting one fitting into the other. In addition, the locking device can be arranged so that after its unlocking by the other connector, for example, in a continued insertion process into the connector, establishes a lock with the other connector, so that the coupled connectors or coupled to the other connector housing can not be separated from each other when the locking device is unlocked and the cannula can be pushed over the cannula by the closure device of the connector or the closure device.

According to a further embodiment, the locking device comprises a linearly movable element and a rotatable element, which are arranged and interact with each other so that the linearly movable element can be displaced or displaced into at least a first position in which rotation of the rotatable element is permitted and the linearly movable element can be displaced or displaced into at least one second position in which rotation of the rotatable element is blocked by the linearly movable element in at least one direction. The linearly movable element may have the shape of a straight or curved rod. Similarly, the rotatable member may also be in the form of a straight or curved rod.

The locking device may be arranged in such a manner on the connection piece, in particular on the housing thereof, that it can be actuated from the outside only by a corresponding element on the other connection piece, such as a nose arranged thereon, and not otherwise readily from the outside of the connection piece accessible and can not be accidentally unlocked.

According to a further embodiment, the rotatable element is set up, in which the connector formed corresponding element, such as a nose, engage, so that the connecting piece and the other connector are coupled together. The element may be the same element on the other connection piece with which the locking device is actuated on the connection piece. The locking can be effected by the linear element of the locking device is placed in a further, possibly further inside the connector lying third position when joining the fittings from the first position in which rotation of the rotatable member is permitted, with a proximal to the outside the fitting directed end of the rotatable member is pivoted about the formed on the other connector corresponding element and the fittings are locked together.

According to another embodiment, the proximal, directed to the outside of the connector end of the rotatable member may be configured and in particular fork-shaped, that it can engage in a corresponding rotatable element of a locking device on the other connector, for example, may have a corresponding pin.

In yet another embodiment, the linearly movable member and the rotatable member are arranged and configured such that the corresponding member formed on the other connector moves the linearly movable member in coupling the connectors to the third position, the linear member pivoting the rotatable member, so that it engages in the formed on the other connector corresponding element to couple the housing of the connector with the other connector.

The locking device may be arranged on the connecting piece or on the movable housing of the connecting piece or on the outer housing. At the connection piece, the movable housing of the connector or the outer housing and a plurality of corresponding locking devices or parts thereof may be arranged. For example, a locking devices or a part thereof may be provided, which locks a displacement of the outer housing relative to the connector and releases when coupling the fittings, while the fittings locked together, as described above in connection with the outer housing. The connecting piece may also comprise one or more filters, in particular sterile filters or bubble separators, according to embodiments. These may be arranged along the conduit, the cannula or between the conduit and the cannula.

Further provided is a connector for drip-free and secure transfer of fluids comprising a closure means closing the fitting and a conduit coupled to the closure means for transmitting a fluid disposed in the fitting, the fitting being configured to mate with another Connector according to the invention, which may be formed according to one of the embodiments described above, can be coupled to produce a drip-free and secure connection.

According to one embodiment, the closure device is a platelet, a membrane or a septum made of a material that can be penetrated by the cannula and automatically closes again after retraction of the cannula. The shutter means may correspond to the above-described shutter means of the first connector according to the above-described embodiments and may have the same construction and the same characteristics.

According to a further embodiment, the closure device in the connection piece in a radial direction with respect to a direction of passage of the cannula through the closure device is at least partially pressurized and compressed over its circumference. As to the compression, the shutter may correspond to the above-described shutter of the first connector according to the above-described embodiments and may have the same construction and the same characteristics.

According to yet another embodiment, the closure device has a convex surface facing the outside of the fitting, through which the cannula enters the closure means. Regarding the convexity of the closure device, the closure device may correspond to the above-described closure device of the first fitting according to the above-described embodiments and may have the same construction and the same characteristics. According to yet another embodiment, the closure means is movably mounted in the fitting and biased with an elastic member towards a proximal end of the fitting. By means of the elastic element, a uniform pressure between the adjoining closure devices of two interconnected fittings can be achieved, whereby manufacturing tolerances can be compensated and also an increase in security against contamination can be achieved by an exiting between the closure devices fluid.

The elastic element may be a coil spring, a leaf spring or a compact body formed of an elastomer.

According to another embodiment, the connection piece has a control device with which a flow of a fluid through the line can be regulated.

According to another embodiment, the control device is movably mounted on the fitting and may be moved between a plurality of positions wherein in a first position the flow of fluid through the conduit is permitted, in a second position the flow of fluid through the conduit is blocked and in a third position the flow of fluid through the conduit is blocked and the volume of the conduit between the proximal end of the conduit in the fitting and the position of the control apparatus on the conduit is increased relative to the second position.

According to a further embodiment, the control device is arranged on the connection piece so that it can be displaced in a position blocking the flow through the line along the line, so that the volume in the line between the position of the control device on the line and one end of the line in the connection piece is increased or decreased.

According to yet another embodiment, the control device comprises a bolt whose ends are received in guides in the fitting and whose position relative to the conduit can be changed so that the inner cross section varies by squeezing the conduit and thus controlling the flow through the conduit can. The control device may correspond to the above-described control device of the first connector according to the above-described embodiments and may have the same construction and the same characteristics.

According to a further embodiment, the connecting piece has a device for generating a negative pressure in the cannula and in the conduit. The device may have a body connected to the cannula or the conduit, the volume of which can be increased to produce the negative pressure. The device preferably serves to generate a negative pressure in the cannula or the line, so that the risk of leakage of a fluid from the cannula is avoided, in particular when separating the connection piece from a further connection piece coupled thereto.

According to another embodiment, the connector is movably disposed in an outer housing, wherein the connector between a first position in which the connector is inserted substantially into the outer housing, and a second position in which the connector is advanced from the outer housing, are moved can, and the connector comprises at least a portion of a locking device which is configured so that the movement of the connector from the second position to the first position is permitted only when the locking device is unlocked, and otherwise locked.

The outer case may correspond to the above-described outer case of the first connector according to the above-described embodiments and may have the same structure and characteristics.

In one embodiment, the control device is coupled to the outer housing and actuated by moving the fitting relative to the outer housing.

According to yet another embodiment, the locking device comprises a linearly movable element and a rotatable element which interact with one another in such a way that the linearly movable element can be displaced into at least a first position in which rotation of the rotatable element is permitted, and linearly movable element can be placed in at least a second position in which rotation of the rotatable member is locked in at least one direction. The linearly movable element may have the shape of a straight or curved rod. Similarly, the rotatable member may also be in the form of a straight or curved rod.

According to one embodiment, the rotatable element is adapted to engage in a locking element of the further connection piece, so that the connection piece and the further connection piece are releasably coupled to one another.

The locking device may at least partially correspond to the above-described locking device on the first connecting piece and have the same structure and the same properties.

Further, the rotatable elements of the locking devices may be adapted to the fittings so as to engage each other when the fittings are coupled together. For this purpose, one of the rotatable elements of the locking devices may be fork-shaped at the terminals at its proximal end facing the other terminal, while the other rotatable element is constructed to have a pin into which the cable-shaped end is coupled the connection pieces engages. Moreover, when the rotatable members are engaged with each other at the time of assembling the fittings or just before, the displacement of the linear member of one of the locking devices and the simultaneous pivoting of both the rotatable members occur so that the relative movements between the outer housings and the respective fitting and also the control devices are simultaneously released ,

In addition, at least one of the rotatable elements of the locking devices is arranged so that the simultaneous rotation of the rotatable elements in the assembly of the fittings, the fittings are locked together, for example, a hook of one of the rotatable elements in the other connector or in a corresponding element at this , such as a nose or a projection engages. Further provided is a connection device for drip-free and secure transfer of fluids with two connection pieces which can be coupled to one another, one of which has the connection piece according to the invention, which can optionally be configured according to one of the above-mentioned embodiments, and the other is a further connection piece, which according to one of can be configured above embodiments.

The connection means allows the fittings to have no contamination by a fluid transferred through the fittings during their coupling and also after their separation on the surfaces facing the outside. Avoidance of contamination of outer surfaces of the fittings can be guaranteed even at high pressures in the pipes of the fittings of up to 3, 5 or 7 bar.

According to one embodiment, the connecting device may comprise an elastic element on or in at least one of the connecting pieces, wherein in the coupled state of the connecting pieces the closing means of the connecting pieces are pressurized by the elastic element in the direction of the passage of the cannula and held against one another.

By applying a pressure between the closure means of the fittings, leakage of a fluid from the connection means between the closure means can be effectively avoided.

According to another embodiment, the connecting device comprises that in the coupled state of the connecting pieces, the cannula of one of the connecting pieces traverses the closing means of both connecting pieces and is connected to the line in the other connecting piece.

According to a further embodiment, the connecting device may comprise, in the coupled state of the connecting pieces, a protruding housing section of one connecting piece, at the proximal end of which the closing device is movably arranged, in a receptacle of the other connecting piece, in which the closing device of FIG another connection piece is arranged, is received positively.

As a result, it can be ensured that a coupling can only take place between mutually compatible connecting pieces. In addition, it is ensured that the release of provided on the fittings locking devices only when assembling compatible connectors by appropriately arranged components or parts, whereby an undesirable leakage of the cannula from the connector and leakage of fluids from the non-coupled connector can be avoided.

According to yet another embodiment, the connecting device comprises that the connecting pieces are respectively arranged in an outer housing and both connecting pieces have locking devices which prevent a movement of the connecting pieces in relation to the respective outer housing in which they are arranged in the separated state of the connecting pieces Locking devices are set up so that they are unlocked simultaneously when joining the fittings.

According to one embodiment, the connecting device may also include that the connecting pieces are coupled to the respective outer housing in such a way that, when the locking devices are unlocked, a displacement of the outer housings relative to the respective connecting piece arranged therein is permitted, and in the assembly of the connecting pieces control devices in both connecting pieces be displaced simultaneously in the displacement of locked positions in positions in which a flow of a fluid through the conduits and the cannula of the fittings is allowed.

Thereby, it can be ensured that the inflow of a fluid from the line into the fitting and the cannula is released only when a fitting is coupled to a fitting compatible therewith, and moreover, a connection between the fittings has been made through the cannula.

According to yet another embodiment, the connecting device may comprise that, when the connecting pieces of the connecting device are pulled apart, the outer housings are removed from one another, while the proximal ends of the connecting pieces are removed from one another. By the displacement of the outer housing in relation to the respective fitting in which they are arranged, the control devices of both fittings simultaneously remain in a second position, from a first position in which the flow of a fluid through the conduit is permitted the flow of fluid through the conduit is blocked and then brought to a third position in which the flow of fluid through the conduit is blocked and the volume of the conduits between the regulators connected by the conduits and the cannula is increased.

By blocking the conduits in both fittings and then increasing the volumes in the conduits in the fittings, a vacuum can be created between the controls in the interconnected fittings to prevent leakage of fluid from the conduit or cannula. This is particularly important in the separation of the fittings and the retraction of the cannula by the closure devices in one of the fittings of particular importance. This can prevent a fluid from getting out of one of the fittings to the outside.

According to a further embodiment, the connecting device has a device for generating a negative pressure in the cannulas and in the lines. The device may have a body connected to one of the cannulas or conduits, the volume of which may be increased to produce the negative pressure. The device is preferably used to generate a negative pressure in the cannulas or the lines, so that the risk of leakage of a fluid from the cannula, in particular when separating the connecting pieces from each other, is avoided.

Furthermore, a method for producing a fluid line between a connecting piece according to the invention, which may be configured according to one of the above-mentioned embodiments, and a further connecting piece, which may also be formed according to one of the embodiments given above.

The method makes it possible to couple two compatible connecting pieces with each other and to produce a closed, drip-free and secure fluid line between the connecting pieces, wherein a discharge of a fluid and a contamination of Au ßenflächen the fittings during the transmission of a fluid through the line and the disconnection of the line can be avoided.

The method comprises unlocking a locking device on one of the connecting pieces by the other connecting piece when assembling the connecting pieces and then displacing the closing devices of both connecting pieces via the cannula of one of the connecting pieces during assembly of the connecting pieces.

By the necessary unlocking of the locking device, which prevents the displacement of the closure device of the connector, in which the cannula is located, or the displacement of the cannula itself, it is ensured that leakage of the cannula from the connector is only possible when the connectors coupled together are.

According to one embodiment, the joining together of the connecting pieces comprises the insertion of a proximal housing section of one of the connecting pieces into a corresponding receptacle of the other connecting piece, wherein the closing devices which are located in the receptacle of the one connecting piece and at or in the proximal end of the housing section of the other connecting piece be pressed against each other.

By pressing the closure devices together, leakage of a fluid from one of the connecting pieces and thus contamination of the outer surfaces of the closure devices and the connecting pieces can be avoided.

According to another embodiment, the method comprises the simultaneous unlocking of control devices on the two fittings for controlling the flow of fluid through the cannulas and conduits in the fittings through the respective other fitting upon assembly of the fittings after the cannula penetrates the closure means at both fittings and a line connection between the fittings has been made.

The simultaneous unlocking of the control devices on the two connecting pieces ensures that, for the first time, fluid or additional fluid, if the connecting piece has already been used, does not enter the cannula until the two connecting pieces have been fitted together. are coupled together.

The simultaneous unlocking of the control devices on the two fittings may further include the release of relative movement between the fittings and the respective outer casings in which the fittings are located, as well as simultaneously locking the fittings together to couple them.

According to another embodiment, the method comprises generating a negative pressure in one of the cannulas or conduits prior to decoupling the fittings. The generation of a negative pressure is used to generate a negative pressure in the cannulas and lines, so that the risk of leakage of a fluid cannulas and lines is avoided, especially when disconnecting the fittings.

According to another embodiment, the method in the decoupling of the connecting pieces on the moving apart of the outer housing, in which the connecting pieces are arranged. When the outer casings move apart, the proximal ends of the connecting pieces remain coupled to one another causing displacement of the outer casings relative to the respective terminals in which they are arranged, whereby the control devices of both terminals preferably simultaneously from a first position in which Flow of a fluid through the line is admitted, in a second position in which the flow of fluid through the line is blocked and then placed in a third position, in which the flow of fluid through the line blocked and the volume of the lines in Region between the connected by the lines and the cannula control devices is increased.

Closing the control devices and then displacing the control devices in the closed state of the conduits increases the volume in the interconnected conduits and cannulas of the fittings in the portion between the control devices, thereby creating a negative pressure in the conduit and cannula which prevents it in that fluid can escape from the cannula, whereby the closure means or surfaces of the closure means located on the outside of the fittings could become contaminated. In one embodiment, the method includes releasing the latch between the fittings once the control devices are in the third position while simultaneously inhibiting relative movement between the fittings and the respective outer casing.

Finally, according to another embodiment, the method may include retracting both occlusion devices via the cannula and disabling the movement of the fitting relative to the closure device once the cannula is withdrawn behind the closure device and releasing the lock between the fittings.

Further features, advantages and features of the present invention will be explained below with reference to an exemplary embodiment of the connector according to the invention as well as a two-connector connecting device with reference to the accompanying drawings, in which

Fig. 1a - c shows diagrammatically two connecting pieces according to an embodiment in a separate state in a view from below (a), in a view from the side (b) and in a view from above (c);

FIGS. 2a-c show the connecting pieces according to the embodiment shown in FIGS. 1a-c in a first connected state in a view from below (a), in a view from the side (b) and in a view from above (c) ;

FIGS. 3a-c show the fittings according to the embodiment shown in FIG. 1 in a second connected state in a view from below (a), in a view from the side (b) and in a view from above (c); and

4a-c, the interconnected fittings according to that shown in Fig. 1

Embodiment in a fully connected state in a view from below (a), in a view from the side (b) and in a view from above (c) shows. In the following, two mutually compatible connecting pieces 1, 3 according to an embodiment will be described with reference to FIGS. 1 to 4. The connecting pieces shown in the figures are shown schematically, wherein the construction of the essential components of the connecting pieces 1, 3 and arranged on the connecting pieces 1, 3 locking means 5, 6, 7 are shown. The figures show the fittings in various states in the course of their coupling.

The first connector 1 in Fig. 1 comprises a body 9 with a receptacle 11 formed therein, in which a movable housing 13 is arranged. In the connector 1 is a fixed mounted cannula 15 with a symmetrical, closed tip 17 which extends into the housing 13. The cannula 15 has below the tip 17 an opening (not shown) through which a fluid, such as a liquid, can escape. The fluid may be supplied through a first conduit 19 coupled to the first cannula 15 and exiting the first connector 1 at the distal end. A first closure device 21, such as a plate, a membrane or a septum, which closes the housing 13, is arranged on the front side thereof.

In Fig. 1, the movable housing 13 is shown in a first position, in which the first closure device 21 is located in the vicinity of the proximal end of the first connector 1. In this position, the tip 17 of the first cannula 15 is retracted inside the housing 13 behind the first closure device 21.

The first connector 1 is movably arranged in a first outer housing 22, in which it is at least partially positively received. The first connection piece 1 can be moved between a first position, in which the first connection piece 1 protrudes from the first outer housing 22, and a second position, in which the first connection piece 1 is inserted substantially into the first outer housing 22 (in FIG c). In FIGS. 1a-c, 2a-c, 3a-c, the first connection piece 1 is in the first position. At the distal end of the first connection piece 1, a spring 20 is arranged in the direction of a rear wall of the first outer housing 22.

In particular, Fig. Lc shows the mounted on the housing 13 first locking device 5 of the first connector 1. The first locking device 5 has a linearly movable Element 23 and a rotatable element 25 on. The rotatable about a pin 26 element 25 is provided at one end with a pin 27 which extends in Fig. Lc in the plane and is guided in an angled guide or slide track 29 of the first connector 1. The angled guide or slide track 29 comprises a first section extending obliquely in relation to the direction of movement between the housing 13 and the first connecting piece 1 and a second section running parallel to the direction of movement between the housing 13 and the first connecting piece 1. If the bolt 27 is located in the obliquely extending first section of the slide track 29, as shown in FIG. 1 a-c, the bolt 27 prevents the housing 13 from being pushed into the connector 1. The linearly movable element 23 prevents in the position shown in Fig. La - c rotation of the rotatable member 25 and is held by a spring 31 in the locked position. Only when the linearly movable member 23 is pushed against the spring force in the first connector 1, as shown in Fig. 2 c, the rotation of the rotatable member 25 is allowed, the further advancement of the linearly movable member 23 into the interior of the connector 1 of this is pivoted out of the locking position, so that the bolt 27 along the parallel to the direction of movement between the housing 13 and the first connector 1 extending second portion of the slide track 29 and thus the housing 13 are moved into the connector 1 and the cannula 15 can penetrate the closure device 21, as can be seen in Figs. 3b and c.

The second locking device 6 of the first connection piece 1, which is mounted on an inner side of the first connection piece 1, has a similar construction to the first locking device 5. The second locking device 6 also has a linearly movable element 33 and a rotatable element 35. The element 35 rotatable about a bolt 36 is provided at one end with a bolt 37, which extends in FIG. 1 a into the plane of the drawing and is guided in a slide track 39 of the first outer housing 22, which in the embodiment shown in FIG shown position of the bolt 37 prevents the first connector 1 can be pushed into the first outer housing 22. The linearly movable element 33, which is held in a proximal position by a spring 40, prevents rotation of the rotatable element 35 in the position shown in FIG. 1a. Only when the linearly movable element 33 is pushed in a distal direction of the first connection piece 1 As can be seen in Fig. 3a, the rotation of the rotatable member 35 becomes released, which is pivoted in a further advancement of the linearly movable member 33 in a distal direction of the connector 1 from the locking position, as can be seen in Fig. 4a, so that the bolt 37 along the link path 39 and thus the connector 1 in the Outer housing 22 can be moved. The element 35 rotatable about the bolt 36 has, at the other end facing the proximal end of the first connector 1, a fork-shaped portion 42 which is adapted to form a pin or bolt-shaped portion 44 at the end of a rotatable element of the second connector 3 intervene.

In addition, the first connection piece 1 comprises a first control device 41 with which the flow through the first line 19 can be regulated and, in particular, released or blocked. The first control device 41 comprises a bolt 43 which extends through the first connection piece 1 perpendicular to the first line 19 (in FIG. 1a, c perpendicular to the plane of the drawing). The ends of the bolt 43 are guided in guides 45 in opposite walls of the first connector 1 in such a way that the bolt 43 can be displaced parallel to the first line 19 according to the course of the guides 45 in the rear portion of the first connector 1, wherein in this Section the first line 19 is pinched by the pin 43 so that a flow through the first line 19 is not permitted, as shown in Fig. La, c. Towards the end of the conduit 19 in the front portion of the first connector 1, the guides 45 of the bolt 43 extend obliquely to the first conduit 19 so that the distance of the bolt 43 from the conduit 19 increases and in the end position of this portion a flow through the first Line 19 is allowed. The first line 19 is no longer squeezed in the end position of the front section. The ends of the bolt 43 passing through the first connector 1 are also fixed or received in lateral walls of the first outer housing 22 facing the corresponding side walls of the first connector 1. The bolt 43 is received in longitudinal openings in the side walls of the outer housing 22, so that a movement of the bolt 43 is allowed perpendicular to the line 19 and the bolt 43 of the predetermined by the guides 45 in the front portion of the first connector 1 movement in which the Distance from the first line 19 increases, can follow.

During a movement of the first outer housing 22 in relation to the first connection piece 1 the bolt 43 is moved together with the first outer housing 22, so that it moves along the first conduit 19 and according to the direction of movement of the flow through the first conduit 19 is opened or locked.

The second connecting piece 3 shown on the right-hand side in the figures has a construction that is complementary to the first connecting piece 1 and matches the first connecting piece 1 in a plurality of components.

The second connection piece 3 comprises at its proximal end a fixed housing section 113 projecting from the second connection piece 3 and extending from the second connection piece 3, in which a second closure means 121, such as a plate, a membrane or a septum, in a socket 116 is arranged, which closes the housing portion 113. The socket 116, in which the closure device 121 is received, is movably arranged in the section 113 and is pressed by a spring 123 against the front proximal end of the housing section 113. In the second connector 3 is a fixed second conduit 119, which emerges with its rear end from the second connector 3. In the direction of the proximal end of the housing section 113, the second line 119 opens into a receptacle 117, which is arranged in or on the socket 116 in front of the second closing device 121. The housing 117 has the receptacle 11 in the first connector 1 corresponding cross-sectional dimensions, so that the housing portion 113 when coupling the second connector 3 with the first connector 1 in the receptacle 11 of the first connection piece 1 can be introduced, wherein the first closure device 21 of the first connection piece 1 and the second closure device 121 of the second connection piece 3 abut against each other, as can be seen in FIGS. 2b to 4b. By the spring 123, the closure means 21 and 121 are pressed against each other with a defined pressure.

Similar to the first connection piece 1, the second connection piece 3 is also movably arranged in a second outer housing 122, in which it is accommodated at least partially in a form-fitting manner. The second connection piece 3 can project between a first position (in FIGS. 1 to 3), in which the second connection piece 3 protrudes from the second outer housing 22, and a second position in which the second connector 3 is substantially inserted into the second outer housing 122 (FIG. 4). At the distal end of the second connecting piece 3, a spring 120 is arranged in the direction of a rear wall of the second outer housing 122. Both outer housing 22 and 122 are ergonomically designed so that they are good and comfortable to grip and the fingers during assembly of the outer housing 22 and 122 have a good grip.

The second connection piece 3 comprises a third locking device 7 similar to the second locking device 6 of the first connection piece 1, which is mounted on an inner side of the second connection piece 3. The third locking device 7 also has a linearly movable element 133 and a rotatable element 135. The rotatable element 135 is provided at one end with a bolt 137 which extends in Fig. La in the plane of the drawing and is guided in an angled guide or slide track 139 of the second outer housing 122, in the in Fig. 1 a - c shown Position of the bolt 137 prevents the connector 3 can be pushed into the outer housing 122. The linearly movable member 133, which is held by a spring (not shown) in a proximal position, prevents rotation of the rotatable member 135. Only when the linearly movable member 133 is pushed in a distal direction of the second fitting 3 does rotation become the rotatable member 135 is released and the rotatable member 135 is pivoted in assembling the fittings 1, 3 by the forked portion 42 of the rotatable member 35 of the first connector 1 from the locking position, so that the bolt 137 along the guide rail 139 and thus the second connector 3 can be moved into the second outer housing 122.

The second connection piece 3 has a control device 141 corresponding to the first connection piece 1, with which the flow through the second line 119 can be regulated and, in particular, released or blocked. The control device 141 comprises a bolt 143, which extends through the second connection piece 3 perpendicular to the line 119 (in FIGS. 1a and 1c perpendicular to the plane of the drawing). The ends of the bolt 143 are guided in guides 145 in opposite side walls of the second connector 3 in such a manner that the bolt 143 can be displaced parallel to the second conduit 119 according to the course of the guides 145 in the rear portion of the connector 3, wherein in this section due to the position of the guides 145, the second line 119th is squeezed by the bolt 143, so that the diameter of the second conduit 119 is reduced and a flow is not allowed. Towards the end of the conduit 119 in the front section of the second connector 3, the guides 145 for the bolt 143 extend in such a way that the distance of the bolt 143 from the conduit 19 increases and a flow through the second conduit 119 is permitted. The ends of the bolt 143 passing through the second fitting 3 are also supported or received in the side walls of the second outer housing 122 opposite to the side walls of the second fitting 3. In a movement of the second outer housing 122 relative to the second connector 3, the bolt 143 is taken from the second outer housing 122 and moved together with it, so that it moves along the second conduit 119 and the flow through the second conduit 119 according to the direction of movement or opened is locked. The bolt 143 is mounted in the walls of the second outer housing 122 so that it can move perpendicular to the second conduit 119 to allow the movement of the bolt 143 in the guides 145 in the front gate of the second connector 3, in which the distance of the Bolzens 143 enlarged from the second line.

For coupling the first connector 1 to the second connector 3, the housing portion 113 of the second connector 3 is inserted into the receptacle 11 of the first connector 1, as shown in Fig. 2. The closure devices 21 and 121 of the connecting pieces 1 and 3 seal off the connecting pieces 1 and 3. In this position of the connecting pieces 1 and 3, the first and the second control device 41, 141 are closed, so that a fluid does not enter the receptacle 117 or the cannula 15 from the first conduit 19 into the cannula 15 or out of the second conduit 119 can.

When the housing portion 113 of the second connector 3 is advanced into the receptacle 11 of the first connector 1, the linearly movable member 23 of the locking device 5 is pushed by a nose 147 at the proximal end of the housing portion 113 inside the first connector 1 and thereby the rotatable element 25 of the first locking device 5 pivoted and unlocked, so that the housing 13 of the first connector 1 can be pushed back into the receptacle 11 of the first connector 1, as shown in Fig. 3 a - c. In this case, the cannula 15 penetrates the first closure device 21 of the first connection piece 1 and then the adjoining thereto second closure means 121 of the second connector 3 and enters the receptacle 117 of the second connector 3. In this case, the fluid connection between the first conduit 19 and the second conduit 119 is closed. The closure devices 21, 121 are pressed together by the spring 123.

At the same time, during advancement of the linearly movable element 23 of the first locking device 5, the rotatable element 25 of the first locking device 5 engages with a hook 146 at its proximal end into the nose 147 at the proximal end of the housing section 113 of the second connecting piece 3, so that the connecting pieces 1 , 3 are locked together and can not be separated. This position is shown in Fig. 3c.

Upon continued pushing together of the first and second connecting pieces 1, 3, the linearly movable element 33 of the second locking device 6 is pushed into the interior of the first connecting piece 1 by a second lug 149 on the housing section 113, which is arranged distally with respect to the first lug 147 , and thereby unlocks the rotatable member 35. The rotatable member 35 then engages with its fork-shaped portion 42 at the proximal end in the pin-shaped proximal portion 44 on the rotatable member 135 of the third locking means 7 of the second connector 3, wherein both rotatable elements 35 and 135 by pushing together the fittings 1, 3 simultaneously pivoted while the bolts 37 and 137 are brought in the angled guide tracks 39 and 139 on the outer housings 22 and 122 in the portions of the guide tracks 39 and 139 which are parallel to the direction of displacement of the first connector 1 and the second connector 3 in the first outer housing 22 and the second outer housing 122 extend and in which the bolts 37 and 137 can be moved parallel to the first line 19 and the second line 119, so that the first connector 1 and the second connector 3 in the outer housing 22nd or 122 can be pushed. Immediately before the rotatable member 35 engages with its proximal end in the rotatable member 135 of the third locking means 7 of the second connector 3, the rotatable member 135 of the third locking means 7 is unlocked by the rotatable member 35, the linearly movable member 133 pushes back against the spring , When pivoting the rotatable element 35, the proximal end, which is the fork-shaped proximal portion 42 and beyond a hookförmi gene portion, locked with its hook-shaped portion on the second nose 149 on the housing portion 113, so that the first connector 1 and the second connector 3 are coupled together.

Once the first fitting 1 and the second fitting 3 are pushed into their respective outer casings 22, 122, the first and second control devices 41, 141 and in particular the bolts 43, 143 are carried along by the first and second outer casings 22, 122 and along the guides or guide tracks 45, 145 guided in the positions in the first connector 1 and in the second connector 3, in which the flow through the first line 19 and second line 119 is allowed. This condition is shown in FIG. On the first outer housing 22 and the second outer housing 122 corresponding interlocking locking devices 151 and 153 are provided, which lock the first and the second outer housing 22 and 122 together. After locking in this position, fluid can be transferred from the first conduit 19 to the second conduit 119 without the risk of droplets escaping from the fittings 1, 3.

To separate the first line 19 from the second line 119, the above-described processes and processes are run in the opposite direction.

First, the latch 151, 153 between the first outer housing 22 and the second outer housing 122 is released. When removing the first and second outer housing 22, 122 from each other, they move relative to the terminals 1 and 3 arranged therein, which are further locked together, so that the bolts 43 and 143 corresponding to the guides 45 in the first connector 1 and the Guides 145 in the second connector 3 are simultaneously brought from the first position in which a flow through the first conduit 19 and second conduit 119 is permitted, in a second position in which the first conduit 19 and the second conduit 119 through the Bolt 43 and 143 is crushed, so that a flow through the lines 19 and 119 is no longer permitted. The squeezing of the lines 19 and 119 is also caused by the springs 20 and 120, which push out the first connector 1 and the second connector 3 from the first outer housing 22 and the second outer housing 122 and thus the bolts 43 and 143 in which lead the flow through the lines 19 and 119 blocking position. By further moving apart the outer housing 22 or 122, while the first connector 1 and the second connector 3 remain locked together, the bolts 43 and 143 are brought into a third position in which the volume in the through the cannula 15 with each other connected lines 19 and 119 between the control devices 41, 141 and between the bolts 43, 143 was increased in relation to the second position. This results in the lines 19 and 119 and the associated cannula 15, a negative pressure, the outlet of a fluid from the cannula 15 through the first closure means 21 and the second closure means 121, in particular when retracting the closure means 21, 121 of the cannula 15 prevented.

The fittings 1, 3 are now in the most extended position from the first and second outer casings 22, 122 and are locked in these positions (this position is shown in Figs. 3a-c). In a further removal of the first and second outer housing 22, 122 from each other, the connecting pieces 1, 3 are taken and also separated from each other. In this case, the housing 13, which is coupled by the first locking device 5 with the housing portion 113 of the second connector 3, pulled out of the first connector 1, wherein the cannula 15 is retracted by the second closure means 121 and then by the first closure means 21 or the closure devices 21 and 121 are pulled out via the cannula 15 (this position is shown in FIGS. 2a-c).

Since the first control device 41 and the second control device 141 are closed and in the position on the first line 19 and second line 119, in which the volume in the lines 19, 119 is increased, is in the lines 19, 119 and in the cannula 15 when retracting the cannula 15, a negative pressure, which prevents fluid droplets remaining on the adjoining closure means 21 and 121, between which a negative pressure can also occur when the tip 17 of the cannula 15 in particular withdrawn from the second closure means 121 becomes.

The retention of fluid droplets on the abutting closure devices 21 and 121 is additionally avoided by the cannula 15, in which the opening not in the top 17, but set back from the side. This causes the opening in the tip 17 to be already behind the first shutter 21 in the housing 13 when the tip 17 is withdrawn from the second shutter 121.

The avoidance of adhesion of fluid droplets to the adjoining closure devices 21 or 121 is also supported by the fact that the outer surface of at least one of the closure devices 21 and 121 has a convex surface.

After retracting the cannula 15 behind the first closure device 21 into the interior of the housing 13 (or pulling out the first closure device 21 in front of the tip 17 of the cannula 15), the housing 13 reaches the position in which the housing 13 is maximally extended from the first connection piece is. The locking between the first locking device 5 and the projection on the housing section 113 is now released and at the same time the housing 13 is locked to the first connector 1. The first and second connecting pieces 1, 3 are now separated from each other. At the same time, the cannula 15 is withdrawn behind the first closure device 21, so that escape of fluid droplets from the first connection piece 1 can be avoided. An escape of fluid droplets from the second connector 3 is now prevented.

Many modifications may be made to the embodiment shown and described without departing from the scope of the following claims.

Reference numerals:

1 first connection piece

3 second connection piece

5 first locking device

6 second locking device

7 third locking device

9 body

11 recording

13 housing

15 first cannula

17 tip

19 first line

20 spring

21 first closure device

22 first outer housing

23 linearly movable element

25 rotatable element

26 bolts

27 bolts

29 Guided tour or slide track

31 spring

33 linearly movable element

35 rotatable element

36 bolts

37 bolts

39 leadership

40 spring

41 first control device

42 fork-shaped section

43 bolts

44 Pin or bolt-shaped section

45 tours

113 protruding housing section

116 version

117 recording

119 second line

120 spring

121 second closure device

122 outer casing

123 spring

133 linearly movable element

135 rotatable element

137 bolts

141 control device

143 bolts

145 tours Hook nose nose locking latch

Claims

claims

A fitting (1) for drip-free and secure transfer of fluids with a closure device (21) which closes the connection piece (1) and a cannula (15) arranged in the connection piece (1), the cannula (15) and the closure means (21) are movable relative to each other between two positions, wherein in a first position, the cannula (15) penetrates the closure device (21), so that the tip (17) of the cannula (15) protrudes from the closure device (21), and in a second position, the cannula (15) is retracted behind the closure means (21), the attachment (1) being configured to be coupled to a corresponding further fitting (3) for establishing a drip-free and secure connection means and the cannula (15) has a closed tip (17) and an opening offset from the tip (17).

2. Connection piece (1) according to claim 1, characterized in that it comprises a housing (13) surrounding at least part of the cannula (15), at the proximal end of which the closure device (21) is arranged, wherein the housing (13) is movable is arranged in the connection piece (1) and is configured such that it is located between a first position, in which the tip (17) of the cannula (15) of the closure device (21) is retracted inside the housing (13), and a second Position in which the cannula (15) passes through the closure device (21) and protrudes outwardly from the housing (13), can be moved.

3. Connector (1) according to any one of claims 1 or 2, characterized in that it comprises a device for generating a negative pressure in the cannula (15).

4. fitting (1) according to one of claims 1 to 3, characterized in that the connecting piece (1) with a cannula (15) connected to the line (19) and a control device (41), with a flow of a fluid through the line (19) can be controlled.

5. fitting (1) according to claim 4, characterized in that the control device (41) is movably disposed on the connecting piece (1) and can be moved between a plurality of positions, wherein in a first position, the flow of a fluid through the conduit (19). in a second position the flow of fluid through the conduit (19) is blocked and in a third position the flow of the fluid through the conduit (19) is blocked and the volume of the conduit (19) between the cannula (15) and the position the control device (41) on the line (19) is enlarged in relation to the second position.

6. fitting (1) according to claim 4 or 5, characterized in that the control device (41) is arranged on the connecting piece (1) that they in a flow through the line (19) blocking position along the line (19). can be offset so that the volume in the line (19) between the position of the control device (41) on the line (19) and one end of the line (19) in the connecting piece (1) is increased or decreased.

7. fitting (1) according to one of claims 4 to 6, characterized in that the Re- gelungsvorrichtung (41) has a bolt (43) whose ends are received in guides (45) in the connection piece (1) and whose position relative to the line (19) can be changed so that the inner cross section by squeezing the line (19 ) and thus the flow through the conduit (19) can be controlled.

8. Connecting piece (1) according to one of claims 1 to 7, characterized in that the connecting piece (1) is movably arranged in an outer housing (22), wherein the connecting piece (1) between a first position in which the connecting piece (1 ) is substantially inserted into the outer housing (22), and a second position in which the connecting piece (1) from the outer housing (22) is advanced, can be moved, and that the connecting piece (1) at least part of a locking device ( 6) configured such that movement of the fitting (1) from the second position to the first position is permitted only when the locking device (6) is unlocked and otherwise locked.

9. fitting (1) according to claim 8 in combination with one of claims 4 to 7,

characterized in that the control device (41) is coupled to the outer housing (22) and actuated by moving the fitting (1) relative to the outer housing (22).

A fitting (1) according to any one of claims 1 to 9, characterized in that it comprises at least part of a locking device (5) which is configured so that the relative movement between the closure means (21) and the cannula (15) is only allowed when the locking device (5) is unlocked, and otherwise locked.

11. Connector (1) according to claim 10, characterized in that the locking Vor- direction (5) has a linearly movable element (23) and a rotatable element (25), which are arranged and interact with each other, that the linearly movable element (23) can be set in at least a first position in which a rotation of the rotatable member (25) is permitted, and the linearly movable member (23) can be set in at least a second position in which rotation of the rotatable member (25) is locked in at least one direction.

12. Connecting piece (1) according to claim 11, characterized in that the rotatable element (25) is adapted to engage in a locking element of the further connecting piece (3), so that the connecting piece (1) and the further connecting piece (3) coupled together are.

The fitting (1) according to claim 12, characterized in that the linearly movable member (23) and the rotatable member (25) are arranged so that the locking member holds the linearly movable member (23) in the second position while simultaneously the rotatable member (25) engages the locking member to couple the terminals (1, 3) together.

14. Connection piece (1) according to one of claims 1 to 13, characterized in that the closure device (21) comprises a plate, a membrane or a septum of a material which can be penetrated by the cannula (15) and after the Retracting the cannula (15) automatically closes again.

15. Connecting piece (1) according to one of claims 1 to 14, characterized in that the closure device (21) in the connecting piece (1) in a radial direction with respect to a direction of passage of the cannula (15) through the closure device (21) at least partially is pressurized and compressed over its circumference.

16. Connecting piece (1) according to one of claims 1 to 15, characterized in that the closure device (21) has a to the outside of the connecting piece (1) directed convex surface through which the cannula (15) from the closure device (21) emerges ,

17. Connector (3) for drip-free and secure transfer of fluids with a closure device (121), which closes the connector (3), and one in the connector (3) coupled to the closure device (121) line (119) for transmitting a Fluid, wherein the fitting (3) is configured to be coupled to another fitting (1) according to any one of claims 1 to 16 for producing a drip-free and secure connection.

18. A fitting (3) according to claim 17, characterized in that the closure means (121) comprises a plate, membrane or septum of a material which can be penetrated by the cannula (15) and after withdrawal of the cannula (12). 15) automatically closes again.

19. Connecting piece (3) according to claim 17 or 18, characterized in that the closure device (121) in the connecting piece (3) in a radial direction with respect to a direction of passage of the cannula (15) through the closure device (121) at least partially along its circumference pressurized and compressed.

20. Connecting piece (3) according to one of claims 17 to 19, characterized in that the Closing device (121) has a directed to the outside of the connector (3) convex surface through which the cannula (15) enters the closure device (121).

21. Connector (3) according to any one of claims 17 to 20, characterized in that the closure device (121) is movably arranged in the connecting piece (3) and is biased with an elastic element in the direction of a proximal end of the connecting piece (3).

22. Connector (3) according to any one of claims 17 to 21, characterized in that the connecting piece (3) has a control device (141), with which a flow of a fluid through the conduit (119) can be controlled.

A fitting (3) according to claim 22, characterized in that the control device (141) is movably mounted on the fitting (3) and can be moved between several positions, wherein in a first position the flow of a fluid through the pipe (119) in a second position the flow of the fluid through the conduit (119) is blocked and in a third position the flow of the fluid through the conduit (119) is blocked and the volume of the conduit (119) between the proximal end of the conduit (119) in the connecting piece (3) and the position of the control device (141) on the line (119) is increased in relation to the second position.

24. Connecting piece (3) according to claim 22 or 23, characterized in that the regulating device (141) is arranged on the connecting piece (3) in such a way that it blocks the flow through the line (119) position along the line (119). can be offset, so that the volume in the line (119) between the position of the control device (141) on the line (119) and one end of the line (119) in the connector (3) is increased or decreased.

25. Connecting piece (3) according to one of claims 22 to 24, characterized in that the control device (141) has a bolt (143) whose ends are received in guides (145) in the connecting piece (3) and its position in relation to Line (119) can be changed so that the inner cross section by squeezing the conduit (119) varies and thus the flow through the conduit (119) can be controlled.

26. Connecting piece (3) according to one of claims 17 to 25, characterized in that the connecting piece (3) is movably arranged in an outer housing (122), wherein the connecting piece (3) between a first position in which the connecting piece (3 ) is substantially inserted into the outer housing (122), and a second position in which the connector (3) is advanced from the outer housing (122) can be moved, and that the connector (3) at least part of a locking device ( 7) configured such that movement of the fitting (3) from the second position to the first position is permitted only when the locking device (7) is unlocked and otherwise locked.

27. A fitting (3) according to claim 26 in combination with any one of claims 22 to 25, characterized in that the control device (141) is coupled to the outer housing (122) and moved by moving the fitting (3) relative to the outer housing (122 ) is pressed.

A fitting (3) according to claim 26 or 27, characterized in that the locking device (7) comprises a linearly movable element (133) and a rotatable element (135) interacting with each other such that the linearly movable element (133) in at least a first position can be displaced in which rotation of the rotatable (135) element is permitted, and the linearly movable element (133) can be displaced into at least a second position, in which rotation of the rotatable element (135) at least in one direction is blocked.

29. Connecting piece (3) according to claim 28, characterized in that the rotatable element (135) is adapted to engage in a locking element of the further connecting piece (1), so that the connecting piece (3) and the further connecting piece (1) releasably with each other are coupled.

30. Connector (3) according to any one of claims 17 to 29, characterized in that it comprises a device for generating a negative pressure in the conduit.

31. Connecting device for non-drip and secure transfer of fluids with two interconnectable fittings (1, 3), wherein one of the fittings (1, 3) a fitting (1) according to any one of claims 1 to 16, 30 and the other connector (3 ) has a connection piece (3) according to one of claims 17 to 30.

32. Connecting device according to claim 31, characterized in that in the coupled state of the connecting pieces (1, 3) the closure means (21, 121) of the connecting pieces (1, 3) by an elastic element at least one of the connecting pieces (1, 3) in the direction the passage of the cannula (15) are pressurized and held against each other.

33. Connecting device according to claim 31 or 32, characterized in that, in the coupled state of the connecting pieces (1, 3), the cannula (15) of one of the connecting pieces (1) passes through the locking devices (21, 121) of both connecting pieces (1, 3) and with the Device (119) in the other connector (3) is connected.

34. Connecting device according to one of claims 31 to 33, characterized in that in the coupled state of the connecting pieces (1, 3) a protruding housing portion (113) of a connecting piece (3), at the proximal end of the closure device (121) is arranged to be movable , in a receptacle (11) of the other connection piece (1), in which the closure device (21) of the other connection piece (1) is arranged, is received in a form-fitting manner.

35. Connecting device according to one of claims 31 to 34, characterized in that the connecting pieces (1, 3) in each case in an outer housing (22, 122) are arranged and both connecting pieces (1, 3) locking means, which movement of the connecting pieces (1). 1, 3) in relation to the respective outer housing (22, 122) in which they are arranged, in the separated state of the connecting pieces (1, 3) prevent, wherein the locking means are arranged so that they are in the assembly of the connecting pieces (1, 3 ) are unlocked at the same time.

36. Connecting device according to claim 35, characterized in that the connecting pieces (1, 3) with the respective outer housing (22, 122) are coupled such that when unlocked locking means a displacement of the outer housing (22, 122) relative to the respective connecting piece (1 3), which is arranged therein, and in assembling the connecting pieces (1, 3) control devices (41, 141) in both connecting pieces (1, 3) are simultaneously displaced from locked positions into positions during displacement in which a flow of a fluid through the conduits (19, 119) and the cannula (15) of the fittings (1, 3) is permitted.

37. Connecting device according to claim 35 or 36, characterized in that when pulling together the connecting pieces (1, 3) of the connecting device the outer housing (22, 122) are removed from each other while the proximal ends of the connecting pieces (1, 3) remain coupled together and by the displacement of the outer housing (22, 122) relative to the respective Connecting piece (1, 3) in which they are arranged, the control devices (41, 141) of both connecting pieces (1, 3) simultaneously from a first position in which the flow of a fluid through the conduit (19, 119) is allowed, in a second position in which the flow of the fluid through the conduit (19, 119) is blocked and then brought into a third position, in the flow of the fluid through the conduit (19, 119) locked and the volume of the lines ( 19, 119) between the through the lines (19, 119) and the cannula (15) connected control devices (41, 141) is increased.

38. A method for producing a fluid line between a connection piece (1) according to one of claims 1 to 16, 30 and a connecting piece (3) according to one of claims 17 to 30, comprising the step of unlocking the locking device (5) of one of the connecting pieces (1 , 3) by the other connecting piece (3, 1) during assembly of the connecting pieces (1, 3) and the step of shifting both closure devices (21, 121) of both connecting pieces (1, 3) via the cannula (15).

39. The method according to claim 38, characterized in that the joining together of the connecting pieces (1, 3) comprises the insertion of a proximal housing section (113) of one of the connecting pieces (3) into a corresponding receptacle (11) of the other connecting piece (1), wherein both closure devices (21, 121) are pressed against each other.

40. The method according to claim 38 or 39, characterized in that it the simultaneous unlocking of control devices (41, 141) on the two connecting pieces (1, 3) for Controlling the flow of a fluid during assembly of the connecting pieces (1, 3) after the cannula (15) has penetrated the closure means (21, 121) on both connecting pieces (1, 3).

41. The method according to any one of claims 38 to 40, characterized in that it comprises the pulling apart of outer housings (22, 122), in which the connecting pieces (1, 3) are arranged, during decoupling of the connecting pieces (1, 3) the outer housings (22, 122) are removed from each other while the proximal ends of the fittings (1, 3) remain coupled with each other, thereby displacing the outer housings (22, 122) relative to the respective fitting (1, 3), in the are arranged, causes control devices (41, 141) of both connectors (1, 3) simultaneously from a first position in which the flow of a fluid through the conduit (19, 119) is permitted, to a second position, in the the flow of fluid through the conduit (19, 119) is blocked and then brought to a third position, in which flow of the fluid through the conduit (19, 119) is blocked and the volume of the conduits (19, 119) between is increased by the control devices (41, 141) connected by the lines (19, 119) and the cannula (15).

A method according to claim 41, characterized in that it comprises the release of the lock between the connecting pieces (1, 3) as soon as the control devices (41, 141) are in the third position, while a relative movement between the connecting pieces (1 , 3) and the respective outer housing (22, 122) is locked.