SARS-CoV-2 Lambda variant
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The SARS-CoV-2 Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19.[1] It was first detected in Peru in December 2020.[1] On 14 June 2021, the World Health Organization (WHO) named it Lambda variant[1] and designated it as a variant of interest.[2] It has spread to at least 30 countries[3] around the world and may be more resistant to COVID-19 vaccines compared to other strains.[4][5] It is also suggested that the Lambda variant is more infectious than the Alpha or Gamma variant.[4]
Mutations
The Lambda genome has the following amino acid mutations, all of which are in the virus's spike protein code: G75V, T76I, Δ246-252, L452Q, F490S, D614G and T859N.[6]
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Amino acid mutations of SARS-CoV-2 Lambda variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[7]
![Amino acid mutations of SARS-CoV-2 Lambda variant plotted on a genome map of SARS-CoV-2 with a focus on the spike.[7]](http://upload.wikimedia.org/wikipedia/commons/thumb/3/3a/SARS-CoV-2_Lambda_variant.svg/7315px-SARS-CoV-2_Lambda_variant.svg.png)
History
First samples of the Lambda variant were detected in Peru in December 2020 and by April 2021, over eighty percent of new cases of COVID-19 in Peru were from the new variant.[1][8]
By June 2021, the Lambda variant had begun to spread through South America and was detected in twenty-nine countries in total, especially in Argentina, Chile and Ecuador.[8][9] The WHO designated the Lambda variant as a "variant of interest" on 14 June 2021.[1] In mid-June 2021, 90.6% of new COVID-19 cases in Arequipa and 78.1% of new cases in Cusco were the Lambda variant according to the Peruvian Ministry of Health.[10]
On 6 July Australia reported its first case of the Lambda variant in an overseas traveller who had been in a New South Wales quarantine hotel in April.[11]
Statistics
| Cases by country (Updated as of 15 July 2021) GISAID[12] | ||
|---|---|---|
| Country | Confirmed cases | Last reported case |
| Chile | 1022 | 29 June 2021 |
| USA | 705 | 2 July 2021 |
| Peru | 571 | 30 May 2021 |
| Mexico | 139 | 30 June 2021 |
| Germany | 101 | 5 July 2021 |
| Argentina | 92 | 24 June 2021 |
| Spain | 76 | 29 June 2021 |
| Ecuador | 68 | 23 June 2021 |
| Israel | 25 | 09 May 2021 |
| France | 21 | 29 June 2021 |
| Colombia | 20 | 04 June 2021 |
| Italy | 11 | 26 June 2021 |
| Switzerland | 11 | 7 July 2021 |
| Saint Kitts and Nevis | 10 | 06 June 2021 |
| Egypt | 8 | 02 May 2021 |
| Canada | 7 | 21 June 2021 |
| United Kingdom | 7 | 18 June 2021 |
| Brazil | 5 | 21 June 2021 |
| Denmark | 5 | 9 July 2021 |
| Poland | 4 | 27 June 2021 |
| Belgium | 2 | 24 June 2021 |
| Netherlands | 2 | 21 June 2021 |
| Aruba | 2 | 02 June 2021 |
| Portugal | 2 | 10 June 2021 |
| Australia | 1 | 03 April 2021 |
| Curacao | 1 | 17 February 2021 |
| Czech Republic | 1 | 02 June 2021 |
| Turkey | 1 | 07 May 2021 |
| Uruguay | 1 | 15 April 2021 |
| Bolivia | 1 | 02 June 2021 |
| World (30 countries) | Total: 2,914 | Total as of 15 July 2021 |
See also
References
- ^ a b c d e "Tracking SARS-CoV-2 variants". World Health Organization. Retrieved 2021-06-17.
{{cite web}}: CS1 maint: url-status (link) - ^ "Tracking SARS-CoV-2 variants". who.int. World Health Organization.
{{cite web}}: CS1 maint: url-status (link) Updated frequently. - ^ "Covid 19 coronavirus: Ultra-contagious Lambda variant detected in Australia". New Zealand Herald. 6 July 2021.
- ^ a b "COVID-19: Lambda variant may be more resistant to vaccines than other strains". World Is One News. 6 July 2021.
- ^ "Lambda variant: What is the new strain of Covid detected in the UK?". The Independent. 6 July 2021.
- ^ Robertson, Sally (27 June 2021). "Lambda lineage of SARS-CoV-2 has potential to become variant of concern". news-medical.net. Retrieved 2021-07-05.
The Lambda variant also contained a novel deletion (Δ246-252) and multiple nonsynonymous mutations (G75V, T76I, L452Q, F490S, D614G, and T859N) in the gene that encodes the viral spike protein.
- ^ "Spike Variants: Lambda variant, aka B.1.1.1". covdb.stanford.edu. Stanford University Coronavirus Antiviral & Resistance Database. 1 July 2021. Retrieved 2021-07-05.
- ^ a b "WHO reports on Lambda: the new variant of COVID-19 that is affecting South America". Entrepreneur. 2021-06-17. Retrieved 2021-06-17.
{{cite web}}: CS1 maint: url-status (link) - ^ Mendez, Rich (2021-06-16). "WHO says delta Covid variant has now spread to 80 countries and it keeps mutating". CNBC. Retrieved 2021-06-17.
{{cite web}}: CS1 maint: url-status (link) - ^ Acosta, Sebastián (2021-06-16). "Coronavirus en Perú | Minsa: El 90,6 % de los contagios en Arequipa se deben a la variante Lambda". RPP (in Spanish). Retrieved 17 June 2021.
- ^ "Covid-19 Australia: Strain more transmissible than Delta hits Australia". News.com.au. 6 July 2021.
- ^ "GISAID - hCov19 Variants". www.gisaid.org. Retrieved 2021-07-02.